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  • Books  (53)
  • E-Books: Biomedical and Life Sciences (AWI only)  (53)
  • Cham :Springer Nature Switzerland :  (53)
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  • 1
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Food science. ; Agriculture. ; Economic geography. ; Botany. ; Environmental management. ; Food Science. ; Agriculture. ; Economic Geography. ; Plant Science. ; Environmental Management.
    Description / Table of Contents: Chapter 1: Saffron and Tulasi -- Chapter 2: Aniseed, Shallot and Caraway -- Chapter 3: European Fill and Indian Dill -- Chapter 4: Poppy Seed.-Chapter 5: Star Anise and Japanese Star Anise -- Chapter 6: Sage -- Chapter 7: Savory and Tarragon -- Chapter 8: Thyme -- Chapter 9: Calamus or Sweet Flag -- Chapter 10: Horse Radish, Long Pepper or Pipli, Galangal -- Chapter 11:Quality Control.
    Abstract: This book is a compendium of rare and unique spices, which have been least researched but hold immense economic potential on a global scale. They are Aniseed, Shallot, Saffron, Caraway or Siah Zira, European or Indian Dill, Poppy, Star Anise and Japanese Star Anise, Sage, Savory, Tarragon, Thyme, Calamus or Sweet Flag, Horse Radish, Galangal, and Long Pepper or Pipli. Some of these are seed spices and others, like Saffron, are grown in the hills of Jammu and Srinagar, India and have varied uses, ranging from being very popular food flavorants to being used for religious purposes. Even within India, the country of the origin for most of the spices listed, many Indians are simply unaware of their immense economic potential. This is also the case with other countries, like Iran, where some spices, like Saffron, is widely used as a food flavorant. The book aims to be a unique compendium of these rare and unique spices to primarily enable researchers to tap into their great economic potential and, on a wider scale, help developmental agencies to tap into their immense potential in global spice trade. The book provides a cross-sectoral multi-scale assessment of developmental possibilities, globally, for rare and unique spices of immense economic importance. .
    Type of Medium: Online Resource
    Pages: IX, 141 p. 5 illus., 4 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031202490
    DDC: 641.3
    Language: English
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  • 2
    Keywords: Agriculture. ; Soil science. ; Microbial ecology. ; Agriculture. ; Soil Science. ; Microbial Ecology.
    Description / Table of Contents: Chapter 1 The perpetual battle of bacteria and phages -- Chapter 2 Orchestration of the plant microbiome for enhanced agriculture -- Chapter 3 Plant growth promoting rhizobacteria to mitigate biotic and abiotic stress in plants -- Chapter 4 Ecology and mechanisms of plant growth promoting rhizobacteria.-Chapter 5 Diversity and evolution of nitrogen fixing bacteria -- Chapter 6 Encapsulation of biofertilizers, biopesticides and biocontrol agents -- Chapter 7 Induced systematic resistance and plant immunity -- Chapter 8 Microbial elicitors for priming plant defense mechanisms -- Chapter 9 Microbial mitigation of abiotic stress in crops -- Chapter 10 Microbial alleviation of abiotic and biotic stresses in rice -- Chapter 11 Nutritional biofortification of crops by microbes -- Chapter 12 Microbial rejuvenation of soils for sustainable agriculture -- Chapter 13 Microbial remediation of agricultural residues -- Chapter 14 The biotechnological story of microbial genes from soil to transgenic plants -- Chapter 15 Microbial biosurfactants in the green agricultural technology -- Chapter 16 Role of microbes in the synthesis of industrial products from lignocellulosic materials.
    Abstract: In the context of rising adverse effects of climate change on agriculture, there is a need for advanced methods and practices to manage soils for production of food and energy. This book presents the latest advances in microbial processes that control plant growth, with focus on genomic tools, microbial interactions with the plant and soils habitats, mobilization of plant nutrients, agricultural waste management, biodegradation, bioremediation, carbon sequestration, land reclamation, plant growth promotion, suppression of plant pathogens, induced systemic resistance and tolerance against biotic and abiotic stresses.
    Type of Medium: Online Resource
    Pages: XV, 458 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031241819
    Series Statement: Sustainable Agriculture Reviews, 60
    DDC: 630
    Language: English
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  • 3
    Keywords: Cytology. ; Virology. ; Neurosciences. ; Cancer. ; Stem cells. ; Sports medicine. ; Cell Biology. ; Virology. ; Neuroscience. ; Cancer Biology. ; Stem Cell Biology. ; Sports Medicine.
    Description / Table of Contents: Monkeypox and Sexually Transmitted Diseases -- Clinical Manifestations of Monkeypox -- Laboratory Diagnosis for Monkeypox: Clinical Practice and Important Points to Be Recognized -- Regulatory Mechanisms of Muscle Mass: The Critical Role of Resistance Training in Children and Adolescent -- HSF1 and Its Role in Huntington's Disease Pathology -- Leveraging Tissue Engineering for Skin Cancer Models -- Application of Drug Repurposing-Based Precision Medicine Platform for Leukaemia Patient Treatment -- Stem Cell-Derived Extracellular Vesicles as a Potential Therapeutic Tool for Eye Diseases: From Benchtop to Bedside -- Cannabinoids as Prospective Anti-Cancer Drugs: Mechanism of Action in Healthy and Cancer Cells -- Direct Reprogramming of Somatic Cells into Induced β-Cells: An Overview.
    Abstract: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of Springer Nature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the 19th volume of a continuing series.
    Type of Medium: Online Resource
    Pages: VIII, 194 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031284205
    Series Statement: Cell Biology and Translational Medicine, 1410
    DDC: 571.6
    Language: English
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  • 4
    Keywords: Medical sciences. ; Statistics . ; Health Sciences. ; Applied Statistics.
    Description / Table of Contents: Preface -- Chapter 1: Regression Analysis -- Chapter 2: Cox Regressions -- Chapter 3: Accelerated Failure Time Models -- Chapter 4: Simple Dataset with Event as Outcome and Treatment as Predictor -- Chapter 5: Simple Dataset with Death as Outcome and Treatment Modality, Cholesterol, and Age as Predictors -- Chapter 6: Glioma Brain Cancer -- Chapter 7: Linoleic Acid for Colonic Carcinoma -- Chapter 8: The Effect on Survival of Maintained Chemotherapy with Acute Myelogenous Leucemia -- Chapter 9: Eighty Four Month Parallel Group Mortality Study -- Chapter 10: The Effect on Survival from Stages 1 and 2 Histiocytic Lymphoma -- Chapter 11: Survival of 64 Lymphoma Patients with or without B Symptoms -- Chapter 12: Effect on Time-to-Event of Group Membership -- Chapter 13: The Effect on Survival of Group Membership -- Chapter 14: Deaths from Carcinoma after Exposure to Carcinogens in Rats -- Chapter 15: Effect of Group Membership on Survival -- Chapter 16: Multiple Variables Regression Study of 2421 Stroke Patients Assessed for Time to Second Stroke -- Chapter 17: Hypothesized 55 Patient Study of Effect of Treatment Modality on Survival -- Chapter 18: One Year Follow-up Study with Many Censored Patients -- Chapter 19: Alcohol Relapse after Detox Program Treated with or without Personal Coach -- Chapter 20: Alcohol Relapse after Detox Program with 3 Predictors -- Chapter 21: Ayurvedic Therapy for Human Immunodeficiency Virus -- Chapter 22: Time to Event other Than Cox -- Chapter 23: Abstracts of the Chapters 1 to 22.
    Abstract: An important novel menu for Survival Analysis entitled Accelerated Failure Time (AFT) models has been published by IBM (international Businesss Machines) in its SPSS statistical software update of 2023. Unlike the traditional Cox regressions that work with hazards, which are the ratio of deaths and non-deaths in a sample, it works with risk of death, which is the proportion of deaths in the same sample. The latter approach may provide better sensitivity of testing, but has been seldom applied, because with computers risks are tricky and hazards because they are odds are fine. This was underscored in 1997 by Keiding and colleague statisticians from Copenhagen University who showed better-sensitive goodness of fit and null-hypothesis tests with AFT than with Cox survival tests. So far, a controlled study of a representative sample of clinical Kaplan Meier assessments, where the sensitivity of Cox regression is systematically tested against that of AFT modeling, has not been accomplished. This edition is the first textbook and tutorial of AFT modeling both for medical and healthcare students and for professionals. Each chapter can be studied as a standalone, and, using, real as well as hypothesized data, it tests the performance of the novel methodology against traditional Cox regressions. Step by step analyses of over 20 data files stored at Supplementary Files at Springer Interlink are included for self-assessment. We should add that the authors are well qualified in their field. Professor Zwinderman is past-president of the International Society of Biostatistics (2012-2015) and Professor Cleophas is past-president of the American College of Angiology (2000-2002). From their expertise they should be able to make adequate selections of modern data analysis methods for the benefit of physicians, students, and investigators. The authors have been working and publishing together for 25 years and their research can be characterized as a continued effort to demonstrate that clinical data analysis is not mathematics but rather a discipline at the interface of biology and mathematics.
    Type of Medium: Online Resource
    Pages: XIV, 224 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031316326
    DDC: 610
    Language: English
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  • 5
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Botany. ; Agriculture. ; Biomolecules. ; Physical biochemistry. ; Macromolecules. ; Plant Science. ; Agriculture. ; Structural Biology.
    Description / Table of Contents: 1. Introduction -- 2. Floral morphology and phenology -- 3. Pollen grain morphology, viability, and insect visitation -- 4. The phenology of Rubus glaucus Benth. characterized by the BBCH scale -- 5.Propagation and cultivation -- 6.Fruit and chromosome number -- 7.Post-harvest physiology and nutritional facts -- 8.Genetic diversity -- 9.Breeding programs -- 10.Morphological diversity -- 11.Rubus glaucus and climate change.
    Abstract: The current book focuses on Mora de Castilla (Rubus glaucus Benth.). It explores aspects, such as origin, phenology, propagation, floral and fruit morphology, arthropod visitors, pollination mechanisms, propagation methods, chromosome number, fruit development, breeding, morphological diversity, and the impact of climate change. It includes novel data about plant phenology, flowering, insect visitors, seed germination, fruit morphology, and allometric relationships. This work includes an in-depth review of the most recently published information on the topic. Mora de Castilla is an economically important fruit crop from the Andes. It has been crossed with other Rubus species due to its high yield and everbearing habit. Currently, it is an economically important plant. It has been hybridized with other Rubus species producing new and better-quality hybrids This book contains numerous photographs selected by the author to provide the reader with detailed information about the plant´s morphological features and arthropod visitors. .
    Type of Medium: Online Resource
    Pages: XVIII, 178 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031317507
    DDC: 580
    Language: English
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  • 6
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Botany. ; Ecology . ; Biodiversity. ; Biotic communities. ; Population biology. ; Plant Science. ; Ecology. ; Biodiversity. ; Community and Population Ecology.
    Description / Table of Contents: 1 -- Introduction -- 2. Southern tropical and subtropical rainforests -- 3. Multi-faced southern seasonal tropics 3.1 Heterogeneity of the savanna biomes: a southern perspective -- 4. Southern mediterranean: an extratropical plant marvel -- 5. Dry face of the ‘wet hemisphere’: southern deserts and semideserts -- 6. Austral temperate forests: a biome-classification conundrum -- 7. Southern ‘steppes’ and other grassy oddballs -- 8. The biomes of the coldest corners of the World -- 9. Synthesis: A New Global Zonobiome System -- 10. Further Challenges and Research Agenda -- References.
    Abstract: This is the first comprehensive and critical evaluation of the biome (large-scale, functional biotic communities) patterns in the Southern Hemisphere. Revising the Heinrich Walter's zonobiome system for the Southern Hemisphere appeared as necessary because of the bioclimatic imbalance between the Hemispheres. This revision resulted in formulation of a new zonobiome system, considering the geographic peculiarities of both Hemispheres, hence creating a new, powerful tool of global nature-resource survey and conservation. The system has a potential to attract the interest of the global climate modeling community as the concept of biome (and associated hierarchical system) has a strong functional focus. All zonal biomes of the Southern Hemisphere are featured, and the major challenges we face in understanding their origins, structure, and functioning are discussed. The book contains a wealth of original data resulting from collation of bioclimatic data and vegetation mapping.
    Type of Medium: Online Resource
    Pages: XIV, 219 p. 71 illus., 69 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031267390
    Series Statement: Biome Ecology, 1
    DDC: 580
    Language: English
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  • 7
    Keywords: Biomedical engineering. ; Surgery, Plastic. ; Biomechanics. ; Otorhinolaryngology. ; Biomedical Engineering and Bioengineering. ; Medical and Health Technologies. ; Plastic Surgery. ; Biomechanical Analysis and Modeling. ; Otorhinolaryngology.
    Description / Table of Contents: Non-Surgical Aesthetic Procedures of the Face -- Aesthetic Surgical Augmentation of the Upper Face and Cheeks -- Aesthetic Surgical Augmentation of the Nose and Lower Face -- Surgical Reconstruction of Craniofacial Malformations -- Reconstructive Facial Surgery: Burns, Trauma, Oncoplastic Repair -- Future Directions for Surgical Advancements -- Cosmetic & Reconstructive Facial Plastic Surgery Related Simulation & Optimization Efforts -- Biomechanics of Facial Plastic Surgery Applications -- Applications of Artificial Intelligence, Machine Learning, and Deep Learning on Facial Plastic Surgeries -- Robotics Applications in Facial Plastic Surgeries -- Engineering Psychology of Facial Plastic Surgery Patients -- Technological Improvements in Facial Plastic, Head and Neck Procedures.
    Abstract: Cosmetic and Reconstructive Facial Plastic Surgery: Medical and Biomedical Engineering and Science Concepts provides an extensive overview of the most recent technological advancements in facial plastic and reconstructive surgeries and head and neck surgery through a thorough review of the literature in biomedical engineering, technology, and medicine. Coverage includes the most recent engineering and computing techniques, such as robotics, biomechanics, artificial intelligence (AI), deep learning (DL), machine learning (ML), and optimization, as well as the medical and surgical aspects of medical and scientific methods, surgical and non-surgical procedure types, complications, patient care, and psychological factors. This book will be a valuable introduction to concepts and advances for otorhinolaryngology, biomedical researchers, academics, and students. Offers extensive coverage and ideas for furthering advancements and research; Provides a broad introduction to the subject; Explores the most recent engineering and computing techniques.
    Type of Medium: Online Resource
    Pages: IX, 398 p. 152 illus., 145 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031311680
    DDC: 610.28
    Language: English
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  • 8
    Keywords: Biology. ; Biological Sciences.
    Description / Table of Contents: 1. Genetic Manipulation in medicinal plants for enhancement of Plant Bioactive compounds -- 2. Exploring endophytes for in vitro synthesis of bioactive compounds in medicinal and aromatic plants -- 3. Omics approaches to study the biosynthesis of bioactive compounds in Medicinal and Aromatic Plant -- 4. Phytochemical diversity and biological activity of basil (Ocimum L.) : Secondary metabolites produced in vitro -- 5. In silico screening – An effective option in exploring Plant metabolites as Biopharmaceutics -- 6.Extreme water-stress on metabolite and elemental accumulation in Plectranthus amboinicus, an aroma-medicinal plant -- 7. RNA Interference (RNAi): A Genetic Tool to Manipulate Plant Secondary Metabolite Pathways -- 8. CRISPR/ Cas 9: Novel Techniques for Enhancing Bioactive Compound Production in Medicinal Plants -- 9. New insights for the production of medicinal plant materials: Ex vitro and in vitro propagation -- 10. Conventional approaches toward production of secondary plant metabolites -- 11. Novel secondary metabolites in tea and their biological role in communicable and non communicable human diseases -- 12. Regulation of Photochemical properties of Hawthorn: a Crataegus species -- 13. Hairy Root Cultures—A Versatile Tool of Secondary Metabolites Production -- 14. Herbosomes: An advanced delivery system for phytoconstituents -- 15. Medicinal flora of the trans Himalayan cold deserts of Ladakh, India -- 16. The medicinal potential and application of in vitro techniques in the improvement of Galega officinalis: An overview -- 17. Influence of biotic and abiotic elicitors on bioactive compounds production in medicinal plants -- 18. Aeroponic and Hydroponics system for medicinal herb.
    Abstract: Plant bioactive compounds are plant-based natural products that display a variety of pharmacological applications. These bioactive compounds are important as medicines, pigments and flavorings since most of the pharmaceutical industries are highly dependent on medicinal plants and their extraction. The types and concentrations of bioactive compounds produced by plants are determined by the species, genotype, physiology, developmental stage and environmental factors during growth, determining the physiological adaptive responses employed by various plant taxonomic groups in coping with the stress and defensive stimuli. In the past two decades there has been a renewed interest in the study of conventional aspects such as elicitors and biotic and abiotic stress factors that influence secondary metabolism during in vitro and in vivo growth of plants. the application of molecular biology tools and techniques are facilitating increased understanding of the signaling processes and pathways involved in the bioactive compounds production in subcellular, cellular, organ and whole plant systems during in vivo and in vitro growth, with application in the metabolic engineering of biosynthetic pathways intermediates. Biosynthesis and Manipulation of Bioactive compounds in Medicinal and Aromatic Plants provides a comprehensive introduction and review of the state-of-the-art biotechnological tools used in enhancement of bioactive compounds in medicinal and aromatic plants. Readers will find a systematic overview of techniques such as Omics, Crisper /Cas9 and RNAi to enhance plant bioactive contents including various in vitro techniques, hairy root culture and transgenic technology to enhance plant bioactive contents using plant tissue culture approaches. The chapters provide an overview of the role of induced mutation, biotic and abiotic stress to increase the bioactive contents in plants, plus the role of endophytes to enhance the contents of plant bioactive compounds and standard operating procedures using hydroponics system of cultivation for significant enhancement of bioactive compounds. This book serves as a single source for researchers working in plant secondary metabolites and the pharmaceutical industry.
    Type of Medium: Online Resource
    Pages: VIII, 431 p. 64 illus., 55 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031352218
    Series Statement: Food Bioactive Ingredients,
    DDC: 570
    Language: English
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  • 9
    Keywords: Stem cells. ; Regenerative medicine. ; Cytology. ; Cancer. ; Inflammation. ; Epigenetics. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering. ; Cell Biology. ; Cancer Biology. ; Inflammation. ; Epigenetics.
    Description / Table of Contents: Endothelialization and Inflammatory Reactions After Intracardiac Device Implantation -- Articular Cartilage Regeneration in Veterinary Medicine -- Adult Stem Cell Therapy as Regenerative Medicine for End-Stage Liver Disease -- An Affordable Approach of Mesenchymal Stem Cell Therapy in Treating Perianal Fistula Treatment -- Virus, Exosome, and MicroRNA: New Insights into Autophagy -- Epitranscriptomics Changes the Play: m6A RNA Modifications in Apoptosis -- The Fingerprints of Biomedical Science in Internal Medicine -- Mesenchymal Stem Cell-Derived Extracellular Vesicles: Progress and Remaining Hurdles in Developing Regulatory Compliant Quality Control Assays -- Pharmacological Effects of Caffeic Acid and Its Derivatives in Cancer: New Targeted Compounds for the Mitochondria -- Systematically Assessing Natural Compounds' Wound Healing Potential with Spheroid and Scratch Assays.
    Abstract: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of Springer Nature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the 17th volume of a continuing series.
    Type of Medium: Online Resource
    Pages: VIII, 248 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031205149
    Series Statement: Cell Biology and Translational Medicine, 1401
    DDC: 571.6
    Language: English
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  • 10
    Keywords: Medicine Research. ; Biology Research. ; Analytical chemistry. ; Toxicology. ; Biomedical Research. ; Analytical Chemistry. ; Toxicology.
    Description / Table of Contents: Microplastic research publications from 1991 to 2020 -- Characterization and toxicology of microplastics in soils, water and air -- Coral feeding behavior on microplastics -- Microplastics remediation in the aqueous environment -- Removal of environmental microplastics by advanced oxidation processes -- Techniques for removal and degradation of microplastics -- Occurrence and removal of microplastics in wastewater treatment plants -- Microplastic souces, transport, exposure, analysis and removal -- Airborne microplastics in outdoor and indoor environments -- Nanoplastic sources, characterization, ecological impact, remediation and policies -- Microplastics in soil-plant systems.
    Abstract: Microplastics and nanoplastics have been recently found in most environmental media and in living organisms, thus representing a serious health concern of yet poorly known adverse consequences. This book summarizes recent findings on the sources, behavior, transformation, toxicity and remediation of microplastics, with focus on soils, water, wastewater, air, soils, plants and corals. Advanced methods for sampling, characterization, removal and degradation of microplastics.
    Type of Medium: Online Resource
    Pages: VIII, 282 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031363511
    Series Statement: Environmental Chemistry for a Sustainable World, 73
    DDC: 610.72
    Language: English
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  • 11
    Keywords: Plant biotechnology. ; Nanobiotechnology. ; Plant molecular biology. ; Agricultural biotechnology. ; Agricultural genome mapping. ; Plant Biotechnology. ; Nanobiotechnology. ; Plant Molecular Biology. ; Agricultural Biotechnology. ; Agricultural Genetics.
    Description / Table of Contents: Preface -- Foreword -- Acknowledgment -- 1. Nanoscience, Nanotechnology and Engineered Nanomaterials - An Introduction -- 2.Nanomaterials and Plant Biomolecules – Basics of Interactions -- 3.Nanomaterials and Phytonanobiotechnology -- 4. CNMs and CDs in Plant Growth 5.Nanofertilizers in Agriculture -- 6.Pesticides and Crop Protection -- 7.Nanotechnology and Crop Management -- 8. Targeted Delivery of Nanopesticides -- 9. Nanopesticides in Agriculture: Some Examples -- 10. Revelance of Nanopesticides and Nanofertilizers in Sustainable Agriculture -- 11. Nano-enabled Agrotechnology: Current Status -- 12. Nano-agro-biotechnology Prospects -- 13. Future Aspects -- Index.
    Abstract: Nanofertilizers and nanopesticides increase crop efficiency because of a several-fold increase in the surface-to-volume ratio of nano-forms of nutrients and their suitability to foliar application. The potential agricultural benefits of these nanomaterials, their modes of action, and the fate of nanomaterials in the soil are all discussed. This book uses a multidisciplinary approach and highlights the expertise of the authors in the fields of materials science, nanotechnology, nanobiosensors, and agricultural research. It describes the details of nanoscale synthesis of materials for targeted delivery; in vitro, in vivo, and field trials experimentation; how to use digital technology for specific solutions including Big Data to create predictive mathematical modelling; along with the core knowledge of plant systems and their biosphere to improve crop yields. Also, the book discusses future perspectives and challenges of nanomaterials in agricultural applications. In summary, this book discusses agricultural nanobiotechnology with its main emphasis on understanding the interactions of nanoscale materials of pesticides and fertilizers. It also covers their application to improve the quality and increase crop yield with a minimum use of the active ingredients attached to the nanocarriers.
    Type of Medium: Online Resource
    Pages: XIV, 187 p. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031413339
    Series Statement: Nanotechnology in the Life Sciences,
    DDC: 631.52
    Language: English
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  • 12
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Applied ecology. ; Human ecology Study and teaching. ; Biology. ; Applied Ecology. ; Environmental Studies. ; Biological Sciences.
    Description / Table of Contents: Part I. Pantheism, Ecology, and Cosmology. Different Perspectives and Traditions -- Chapter 1. Brief History of the Organism and the Relationship between the Whole and its Parts -- Chapter 2. Stoic Pantheism and Environmental Ethics in Pliny the Elder -- Chapter 3. The Presence of God in Creation: The Medieval Motifs of Ontological Continuity, Light and Sympathy for Creatures -- Chapter 4. Nature, Venustas, and Harmony -- Chapter 5. Spinoza: Ecosystemic Consequences of the Intersections between Pantheism, Panentheism, and Aacosmism -- Chapter 6. Schleiermacherean Panentheism and Ecology -- Chapter 7. Rumi and Tagore on Being-with-Nature -- Chapter 8. The Withdrawal of God and Man as Co-creator in Hans Jonas’ Cosmogonic Conjecture -- Chapter 9. Hans Jonas And Pantheism: On Ecology and the Problematic Relationship between God, World, and Man -- Chapter 10. The Evolutionary Process Leading up to the Anthropocene as Seen Through Pierre Teilhard de Chardin’s Cosmic Christology -- Chapter 11. Influences of the Spinozian Philosophy in the Environmental Activism of Arne Naess -- Part II. Current Ecological Concerns and Cosmologies: Exploring Pantheism -- Chapter 12. Raimon Panikkar’s Sacred Secularity: An Advaita Interpretation to Understand the Sacredness of Nature -- Chapter 13. Spinozism and Native Americans on Pantheism and Panentheism -- Chapter 14. Ground of Being: The panentheism of Paul Tillich, Earth Care, and Intercultural Dialogue -- Chapter 15. God, Home, and Thinking in the Place: What kind of pantheism did Thoreau Endorse? -- Chapter 16. Genesis 1 as Ecosophy -- Chapter 17. Panentheism in Christian Ecotheology -- Chapter 18. Theism Versus Pancomprehensions -- Chapter 19. The Hidden Theology in the New Naturalisms -- Chapter 20. Towards a Speculative Ecology. Monads, Habits, and the Non-otherness of the World -- Chapter 21. Anthropocene Narratives and New Cosmologies -- Chapter 22. System as Paradigm for a New World View -- Part III. From Pantheism to Ethics and Politics -- Chapter 23. Pantheism: Destruction of Boundaries? -- Chapter 24. Intrinsic Values, Pantheism, and Ecology: Where Does Value Come From? -- Chapter 25. Humans are Humus: An Analysis of Boff’s Panentheistic Ecotheology in the Framework of the Biocultural Ethic -- Chapter 26. On the Compatibility Between Panentheism and Fragmentation: An Experimental Ecofeminist Loosening of the “in” in Allingottlehre -- Chapter 27. Hossein Nasr on the Environmental Crisis -- Chapter 28. Francis Hallé’s Project for a Large Primary Forest in Western Europe and a New Understanding of Our Relationship with the Biosphere.
    Abstract: Environmental ethics arises from the harmfulness of human beings with respect to non-human species and, more generally, to the environment. A common starting point for environmental ethics is that human beings are responsible for damaging nature. The famous four laws of ecology express this guilt on the part of human beings, who very often voluntarily violate the behavioral indications that emerge from nature itself. Eco-theology suggests when humans destroy the natural world, we are wounding God. Such an idea implies a possible coincidence of God with the natural world. From this assumption, various questions emerge: what is the kind of coincidence between God and the natural world? Are God and the ecosystem coextensive? If so, are we re-sacralizing the natural world and grounding intrinsic values in theological postulates and statements? These questions lead us to reconsider the cosmological assumptions that ground our environmental judgements. This book will focus on the cosmological assumptions of pantheism, discussing the symmetrical (or asymmetrical) relationships between God and the finite ways in which God manifests Godself. This book is divided into three parts: first, the question of pantheism is approached from different traditions and with a special focus on the main thinkers, from Greek Stoicism to the present day. Second, current ecological concerns are considered in relation to pantheistic cosmology: from the discussion of the different “pan-conceptions” to the problem of evil, to Anthropocene. Finally, the book will focus on ethical issues in the field of the current environmental crisis with a huge connection with the pantheistic cosmologies. This book is oriented to a wide public, interested in environmental issues and looking for an approach from different cultures and traditions. Evidently, due to its “academic” nature, this book is intended for researchers interested in eco-theology and the relationship between pantheism and ecology.
    Type of Medium: Online Resource
    Pages: XXI, 366 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031400407
    Series Statement: Ecology and Ethics, 6
    DDC: 333.9516
    Language: English
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  • 13
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Biotic communities. ; Population biology. ; Bioclimatology. ; Landscape ecology. ; Urban ecology (Biology). ; Community and Population Ecology. ; Climate Change Ecology. ; Landscape Ecology. ; Urban Ecology.
    Description / Table of Contents: Chapter. 1. Introduction -- Chapter. 2. Life Processes -- Chapter. 3. Environmental Analysis -- Chapter. 4. Population Ecology -- Chapter. 5. Community Ecology -- Chapter. 6. Landscape Ecology and Conservation Biology -- Chapter. 7. Forest Ecosystems -- Chapter. 8. Lake Ecosystems -- Chapter. 9. Stream Ecosystems -- Chapter. 10. Wetland Ecosystems -- Chapter. 11. Marine Ecosystems -- Chapter. 12. Agroecosystems -- Chapter. 13. Ecological Models -- Chapter. 14. Atmospheric Influences, Global Warming, and Climate Change -- Chapter. 15. Tropical Ecology and Deforestation -- Chapter. 16. The Challenges of Human Population Growth -- Epilogue -- Study Questions -- Glossary of Terms -- References -- Index.
    Abstract: The goal of this book is to convey the rich perspectives, principles, and enchantment of ecology to a broad audience of students and lifelong learners. The book is based on the belief that the science of ecology is best understood by examining familiar ecosystems from the natural world and weaving fresh insights and ecological concepts into an ecosystems framework to reveal the patterns, processes, and interactions that are the foundation of sustainable living systems in our biosphere. In the spirit of that teaching philosophy, the core of this book focuses on specific ecosystems that are familiar to most of us (e.g., forests, wetlands, streams, lakes, and the like). Taken as a whole, the chapters of this text are intended to provide a conceptual framework and an intellectual pathway for understanding and interpreting the ecology of the biosphere using elements of population, community, ecosystem, and landscape ecology. Equipped with this toolkit of ecological literacy, readers and students will hopefully be better prepared to make personal, business, and civic or governmental decisions that are consistent with a healthy and sustainable Earth.
    Type of Medium: Online Resource
    Pages: XIII, 284 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031452598
    DDC: 577.82
    Language: English
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  • 14
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Medicine Research. ; Biology Research. ; Anatomy. ; Information visualization. ; Biophysics. ; Biomedical Research. ; Anatomy. ; Data and Information Visualization. ; Bioanalysis and Bioimaging.
    Description / Table of Contents: Chapter 1. The Importance of Integrating the Visual Arts into the Medical Curriculum -- Chapter 2. Using Medical Illustration to Improve Understanding of Endometriosis -- Chapter 3. Editorial Medical and Scientific Illustration -- Chapter 4. Current Approaches in Narrative Medical Visualization -- Chapter 5. Animation for Science Communication: A Description of the Production Process and Contexts for Using Science Animation -- Chapter 6. Effect of the Rings: A Visual Story Design Comparing Three Chemical Characters -- Chapter 7. Diabetes Year One, Random Fluctuations and Mental Goblins: Auto-Ethnographic Pathographies and Medical Comics -- Chapter 8. Playing with Science: Games as a Medium of Science Communication -- Chapter 9. Increasing Microbiology Literacy about the Public Health Threat of Antimicrobial Resistance Through Art-Science Interactions -- Chapter 10. Collaged Creatures: Using Collage Art Practice and Posthuman Ethics to Discuss Bioengineering Hybrids.
    Abstract: This edited book explores the breadth of approaches undertaken by scientists, artists and communicators in their crucial role making science accessible, engaging and impactful. Contemporary approaches in science illustration and visualization include a variety of creative methodologies that are valuable for effective communication, teaching, learning and professional practice. These range in method from anatomical drawings used in medical curricula, to 2D animations and editorial illustrations available in the public realm. They also include unexpected approaches such as the use of tabletop board games, comics and collage in understanding our bodies, emergent health threats and cutting-edge science developments. If you are a scientist seeking to enhance your ability to communicate your research or an artist interested in biomedical visualization, this volume serves as an introduction to contemporary approaches in science illustration and communication. By understanding the creative methods and techniques employed in this field, we can collectively work towards fostering a deeper appreciation of art in science, and continue to captivate and inspire audiences worldwide. .
    Type of Medium: Online Resource
    Pages: XVI, 252 p. 158 illus., 140 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031416521
    Series Statement: Biomedical Visualization, 4
    DDC: 610.72
    Language: English
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  • 15
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Plant anatomy. ; Plants Development. ; Plant physiology. ; Plant ecology. ; Plant diseases. ; Plants Reproduction. ; Plant Anatomy and Morphology. ; Plant Development. ; Plant Physiology. ; Plant Ecology. ; Plant Pathology. ; Plant Reproduction.
    Description / Table of Contents: Abstract -- Resumen -- Introduction -- Material and Methods -- History of the genus -- Morphology -- Habit, sheaths, ligules and blades -- Inflorescences Spikelets -- Texture and ornamentation of the upper anthecium -- Foliar anatomy -- Chromosome numbers -- Phylogeny and evolution -- Geographic distribution -- Taxonomic treatment -- Key of sections and ungrouped species.-Species -- Excluded species -- Acknowledgments -- List of taxa -- Literature cited -- List of exsicatta -- Index of local names -- Index of scientific names.
    Abstract: This work will be volume 124 in the Flora Neotropica Monograph book Series, Lawrence M. Kelly (Editor-in-Chief). Flora Neotropica volumes provide taxonomic treatments of plant groups or families growing in the Americas between the Tropic of Cancer and the Tropic of Capricorn. This monograph on Panicum (Poaceae), known as panicgrass, was written by the world-leading authority on this plant group. A total of one genus and 63 species are described. It also includes information on conservation, phylogenetic relationships, taxonomic history, ecology, cytology, and anatomy, among other topics. This is the first comprehensive volume on this topic since the 1920s and is lavishly illustrated with line drawings, black and white photographs, and distribution maps.
    Type of Medium: Online Resource
    Pages: XLVII, 293 p. 79 illus., 3 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031337680
    Series Statement: Flora Neotropica, 124
    DDC: 571.32
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Biotechnology. ; Plant genetics. ; Environmental policy. ; Biotechnology. ; Plant Genetics. ; Environmental Policy.
    Abstract: This book is a translation of an original French edition. The translation was done with the help of artificial intelligence. A subsequent human revision was done primarily in terms of content, so that the book will read stylistically differently from a conventional translation. The evolution of genome’s modification by genetic engineering was characterized by a major technological breakthrough with the discovery of CRISPR in 2012. A distinction is now made between first-generation biotechnologies developed in the 20th century and current second-generation biotechnologies, NGT or New Genomic Techniques, including genome editing. How do we consider these genomic modifications compared to those that occur spontaneously in nature? What are the applications of these techniques in the fields of plants, animals, and human health? What prospects in terms of development and independence for countries and at least what regulations are in force on the different continents? The book questions what GMOs are, genome editing products and the place of genomic transformations today and tomorrow in our societies. It tries to give some geostrategic and regulatory benchmarks on biotech products in order to better understand the current issues.
    Type of Medium: Online Resource
    Pages: XXI, 157 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031382376
    DDC: 660.6
    Language: English
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  • 17
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Cancer Treatment. ; Cancer. ; Tumors Immunological aspects. ; Stem cells. ; Oncology. ; Cancer Therapy. ; Cancer Biology. ; Tumour Immunology. ; Cancer Stem Cells. ; Oncology.
    Description / Table of Contents: Cancer: A Complex Problem Requiring Interdisciplinary Research -- Tumor Immunology and Immunotherapy -- New Approaches Targeting Immuno-oncology and Tumor Microenvironment -- Tumor Infiltrating Lymphocytes as Markers of the Antitumor Therapy Efficacy: Myth or Reality? -- Recent Innovative Approaches to Intensify the Efficacy and Safety of CAR-T Cell Therapy in Cancers -- An Updated Focus on Immune Checkpoint Inhibitors and Tubulointerstitial Nephritis -- Cancer Stem Cell as a Target for Immunotherapeutic Approach -- Immunological Properties of Manipulated Hematopoietic Stem Cell Grafts -- Recent Development of Quinoline Derivatives as Anticancer Agents: 2015-2022 -- Antitumor Immunotherapy: Effect of COVID-19 in Cancer Patients -- The Use of Immunotherapy in Cancer Patients with Autoimmune Diseases -- The Effects of Low-dose Non-ionizing and Ionizing Radiation on Wound Healing and Cancer -- How Is Cancer Under the Sea? Hyperbaric Oxygen Therapy in Cancer -- Interventional Oncology Techniques: A Primer for Non-Users -- Future Perspectives of Phytochemicals in Cancer Therapy -- Integrated Palliative Cancer Care: From an Interdisciplinary Perspective -- Correction to: Cancer: A Complex Problem Requiring Interdisciplinary Research.
    Abstract: Cancer treatment is a challenging issue, while the treatment modalities have extended from traditional surgery, chemotherapy, and radiation therapy to new therapeutic approaches, including targeted therapy, immunotherapy, stem cell transplantation, and hormone therapy. Therefore, an interdisciplinary approach is needed to find a better therapeutic protocols in order to increase the prognosis and quality of life of patients with cancer. The second volume of the “Interdisciplinary Cancer Research” series, entitled “Cancer Treatment: An Interdisciplinary Approach” publishes comprehensive volumes on different cancer treatment modalities and presents the most updated and peer-reviewed articles on cancer therapy. This interdisciplinary series is of special value to researchers and practitioners working on cell biology, immunology, hematology, biochemistry, genetics, oncology and related fields. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for researchers and clinicians who wish to extend their knowledge on cancer treatment.
    Type of Medium: Online Resource
    Pages: XIII, 426 p. 67 illus., 60 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031439834
    Series Statement: Interdisciplinary Cancer Research, 2
    DDC: 616.994
    Language: English
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  • 18
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Cancer. ; Cancer Treatment. ; Tumors Immunological aspects. ; Immunotherapy. ; Cancer Genetic aspects. ; Stem cells. ; Cancer Biology. ; Cancer Therapy. ; Tumour Immunology. ; Immunotherapy. ; Cancer Genetics and Genomics. ; Cancer Stem Cells.
    Description / Table of Contents: Interdisciplinary Approach in Hepatobiliary Cancers -- Liver Cancer: Interdisciplinary Approach -- The Immune System in Liver Cancer: From Beginning to Progression -- The Tumor Microenvironment in Hepatocellular Carcinoma -- Metabolic Alterations of Hepatocellular Cancer Stem Cells -- Τhe Role of Senescence in NASH-related HCC -- Regulators of Genetic Risk for the Progression of Non-alcoholic Fatty Liver Disease to Hepatocellular Carcinoma: Reconstruction of Transcriptional Network and Signature-Based Metabolic Profiling -- Tumor Microenvironment and Immunotherapy in Advanced Biliary Tract Cancers -- Fibrosis and Immunotherapy in Hepatocellular Carcinoma -- Liver Cancer and the Curative Potential of Nanomedicine -- Locoregional Therapies for Hepatocellular Carcinoma -- Drug Resistance in Hepatocellular Carcinoma -- Liver Stereotactic Body Radiotherapy.
    Abstract: Hepatobiliary cancers, including hepatocellular carcinoma and biliary tract cancers, have high rate of mortality and low survival rate. The third volume of the “Interdisciplinary Cancer Research” series, entitled “Hepatobiliary Cancers: An Interdisciplinary Approach” publishes comprehensive volumes on mechanisms of hepatobiliary cancers and therapeutic modalities and presents the most updated and peer-reviewed chapters on hepatobiliary cancers. This interdisciplinary series is of special value to researchers working on cell biology, immunology, biochemistry, genetics, and practitioners working on oncology and gastroenterology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for researchers, oncologists, and gastroenterologists who wish to extend their knowledge on hepatobiliary cancers.
    Type of Medium: Online Resource
    Pages: XI, 365 p. 22 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031445286
    Series Statement: Interdisciplinary Cancer Research, 3
    DDC: 571.978
    Language: English
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  • 19
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Cancer. ; Cancer Treatment. ; Oncology. ; Immunotherapy. ; Tumors Immunological aspects. ; Nanomedicine. ; Cancer Biology. ; Cancer Therapy. ; Oncology. ; Immunotherapy. ; Tumour Immunology. ; Cancer Nanotechnology.
    Description / Table of Contents: Interdisciplinary Approach in Gastrointestinal Cancers -- Gastrointestinal Cancers: What Is the Real Board of Microenvironment and the Role of Microbiota-Immunity Axis -- Epithelial-Mesenchymal Transition in Gastrointestinal Cancer: From a Basic to a Clinical Approach -- Metabolomics of Gastrointestinal Cancers -- Deregulation of Immune System in Gastric Cancer Development, How Immune Nutrition Might Restore the Functions of Immune Cells -- Helicobacter pylori Virulence Factors, Pathogenicity, and Gastric Cancer -- Gastric Cancer and Helicobacter pylori -- Role of Neuromodulators in Regulation of the Tumor Microenvironment of Gastric and Colorectal Cancers -- The Role of Tumor Microenvironment in Colon Cancer -- Unraveling the Esophageal Cancer Tumor Microenvironment: Insights and Novel Immunotherapeutic Strategies -- The Interplay Between Immunity and Gut Microbiota in Colon Cancer -- Immunotherapy in Gastrointestinal Cancer Focusing on CAR-T Cell Therapy -- Development of Biocompatible Nanocarriers for the Treatment of Colorectal Cancer -- Challenges of Onco-therapeutics in Early Onset Colorectal Cancer -- Unintentional Weight Loss and Malnutrition After Esophageal Cancer and Treatment -- Current Clinical Landscape of Immunotherapeutic Approaches in Pancreatic Cancer Treatment. The Tumor Microenvironment in Pancreatic Cancer and Challenges to Immunotherapy. .
    Abstract: Gastrointestinal cancers are among the most prevalent malignancies worldwide, with high rate of global cancer incidence and cancer-related death. Gastrointestinal cancers include esophageal cancer, gastric cancer, colorectal cancer, pancreatic cancer, and liver cancer, which all, except the last one, are covered in this volume. The fourth volume of the “Interdisciplinary Cancer Research” series, entitled “Gastrointestinal Cancers: An Interdisciplinary Approach” publishes comprehensive volumes on mechanisms of gastrointestinal cancers and novel immunotherapy opportunities and presents the most updated and peer-reviewed chapters on gastrointestinal cancers therapy. This interdisciplinary series is of special value to researchers working on cell biology, immunology, biochemistry, genetics, and practitioners working on oncology and gastroenterology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for researchers, oncologists, and gastroenterologists who wish to extend their knowledge on gastrointestinal cancers.
    Type of Medium: Online Resource
    Pages: XI, 404 p. 22 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031483714
    Series Statement: Interdisciplinary Cancer Research, 4
    DDC: 571.978
    Language: English
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    Keywords: Introduced organisms. ; Botany. ; Plant ecology. ; Biodiversity. ; Population biology. ; Environment. ; Invasive Species. ; Plant Science. ; Plant Ecology. ; Biodiversity. ; Population Dynamics. ; Environmental Sciences.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. How to use the Field Manual? -- Chapter 3. Species’ Profile.
    Abstract: The book “Field Manual on Alien Flora of Kashmir Himalaya: Casual, Naturalised and Invasive Plants” has been prepared with two main goals in mind: (i) to promote awareness on the threats of invasive alien plants to biodiversity, ecology and environment, and (ii) to encourage research on, and management of, the alien plants. The Manual contains concise information on the taxonomy, ecology, invasion status, impacts, distribution and illustrated photo-plates of the alien plant species of Kashmir Himalaya, India. The Manual has three chapters: Chapter-I provides a general introduction to the discipline of invasion ecology. Chapter-II guides the readers on how to use the Manual, including brief information on the study region, methods, definitions and terminology used. Chapter-III comprises the bulk of this Manual, providing profile of 100 alien plant species with scientific information on the botanical, english and local names, taxonomic characters, ecological traits, current invasion status (casual, naturalised and invasive), impacts, native range, species’ distribution-map in Kashmir Himalaya and coloured illustrations that will aid in field identification. It is hoped that the Manual will increase awareness on the threats posed by plant invasions among all the stakeholders - researchers, land managers, policy makers, environmentalists, naturalists, citizen-scientists, students, and the general public. It will also help in promoting research, formulating policies and planning management actions to deal with invasive alien species.
    Type of Medium: Online Resource
    Pages: XVI, 226 p. 204 illus., 203 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031338472
    Series Statement: Invading Nature - Springer Series in Invasion Ecology, 15
    DDC: 578.62
    Language: English
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  • 21
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Evolution (Biology). ; Psychology. ; Model theory. ; Evolutionary Biology. ; Evolutionary Theory. ; Behavioral Sciences and Psychology. ; Model Theory.
    Description / Table of Contents: 1 On the majortransitions -- 1.1 Introduction -- 1.2 Symmetry and symmetry-breaking -- 1.3 Resources -- 1.4 Cognition in non ergodic systems -- 1.5 Theprebiotic`bigbang' -- 1.6 Biological`recombination transparency' -- 1.7 A simple application -- 1.8 Specialization and cooperation: multiple workspaces -- 1.9 Discussion -- 1.10 Mathematical Appendix -- 1.11 References -- 2 On the Extended Evolutionary Synthesis -- 2.1 Introduction -- 2.2 First notions -- 2.3 The basic theory -- 2.4 Examples -- 2.5 More theory:selection pressureas shadowprice -- 2.6 Extending the models -- 2.7 Discussion -- 2.8 Mathematical Appendix -- 2.9 References -- 3O On regulation -- 3.1 Introduction -- 3.2 Theory -- 3.3 Applications -- 3.4 Discussion -- 3.5 Mathematical Appendix -- 3.6 References -- 4 Punctuated regulation as an evolutionary mechanism -- 4.1 Introduction -- 4.2 Fisher Zeros reconsidered -- 4.3 Extinction I:Simple noise-induced transitions -- 4.4 Extinction II: More complicatednoise-induced transitions -- 4.5 Extinction III: Environmental shadow price -- 4.6 Discussion -- 4.7 Mathematical Appendix -- 4.8 References -- 5 Institutional dynamics under selection pressure and uncertainty -- 5.1 Introduction -- 5.2 A Rate Distortion Theorem model of control -- 5.3 Selection pressure dynamics -- 5.4 Destabilization by delay -- 5.5 Extending the Data Rate Theorem -- 5.6 Moving on -- 5.7 Reconsideringcognition\textit{AnSich -- 5.8 Changingtheviewpoint -- 5.9 Discussion -- 5. References -- 6O n`Speciation':Fragmentsizeininformationsystemphasetransitions -- 6.1 Introduction -- 6.2`Simple'phasetransition -- 6.3 Phasetransitionsinnetworksofinformation-exchangemodules -- 6.4 Discussion -- 6.5 MathematicalAppendix:`Biological'renormalizations -- 6.6 References -- 7 Adaptingcognitionmodelstobiomolecularcondensatedynamics -- 7.1 Introduction -- 7.2 Resources -- 7.3 Cognition -- 7.4 PhasetransitionsI:Fisherzeros -- 7.5 Cognitive`reactionrate' -- 7.6 PhasetransitionsII:Signaltransductionandnoise -- 7.7 Discussion -- 7.8 MathematicalAppendix:Groupoids -- 7.9 References -- 8 EvolutionaryExaptation:Sharedinterbrainactivityinsocialcommunication -- 8.1 Introduction -- 8.2 Correlation -- 8.3 Cognition -- 8.4 Dynamics -- 8.5 Cognitionrate -- 8.6 Anexample -- 8.7 Cooperation:Multipleworkspaces -- 8.8 Networktopologyisimportant -- 8.9 Timeandresourceconstraintsareimportant -- 8.10 Furthertheoreticaldevelopment -- 8.11 Discussion -- 8.12 MathematicalAppendix -- 8.13 References -- 9 Afterward.
    Abstract: From the ‘punctuated equilibrium' of Eldrege and Gould, through Lewontin's ‘triple helix' and the various visions and revisions of the Extended Evolutionary Synthesis (EES) of Laland and others, both data and theory have demanded an opening-up of the 1950's Evolutionary Synthesis that so firmly wedded evolutionary theory to the mathematics of gene frequency analysis. It can, however, be argued that a single deep and comprehensive mathematical theory may simply not be possible for the almost infinite varieties of evolutionary process active at and across the full range of scales of biological, social, institutional, and cultural phenomena. Indeed, the case history of 'meme theory' should have raised a red flag that narrow gene-centered models of evolutionary process may indeed have serious limitations. What is attempted here is less grand, but still broader than a gene-centered analysis. Following the instruction of Maturana and Varela that all living systems are cognitive, in a certain sense, and that living as a process is a process of cognition, the asymptotic limit theorems of information and control theories that bound all cognition provide a basis for constructing an only modestly deep but wider-ranging series of probability models that might be converted into useful statistical tools for the analysis of observational and experimental data related to evolutionary process. The line of argument in this series of interrelated essays proves to be surprisingly direct.
    Type of Medium: Online Resource
    Pages: XX, 162 p. 40 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031298790
    Series Statement: SpringerBriefs in Evolutionary Biology,
    DDC: 576.8
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Human physiology. ; Physiology. ; Proteins . ; Cytology. ; Human Physiology. ; Animal Physiology. ; Protein Biochemistry. ; Cell Biology.
    Description / Table of Contents: The Endocannabinoid System in Caenorhabditis Elegans -- Inherited Ventricular Arrhythmia in Zebrafish: Genetic Models and Phenotyping Tools -- The Biochemistry & Physiology of a Disintegrin and Metalloproteinases (ADAMs and ADAM-TSs) in Human Pathologies -- A Review: Uses of Chitosan in Pharmaceutical Forms -- Cell-to-Cell Crosstalk: A New Insight into Pulmonary Hypertension. .
    Abstract: The Endocannabinoid System in Caenorhabditis elegans Rubén Estrada-Valencia, María Eduarda de Lima, Aline Colonnello, Edgar Rangel-López, Nariani Rocha Saraiva, Daiana Silva de Ávila, Michael Aschner, and Abel Santamaría Inherited Ventricular Arrhythmia in Zebrafish: Genetic Models and Phenotyping Tools Ewa Sieliwonczyk, Vladimir V. Matchkov, Bert Vandendriessche, Maaike Alaerts, Jeroen Bakkers, Bart Loeys, and Dorien Schepers The Biochemistry and Physiology of a Disintegrin and Metalloproteinases (ADAMs and ADAM-TSs) in Human Pathologies Deepti Sharma and Nikhlesh K. Singh A Review: Uses of Chitosan in Pharmaceutical Forms Olimpia Daniela Frenț, Laura Vicaș, Tunde Jurca, Stefania Ciocan, Narcis Duteanu, Annamaria Pallag, Mariana Muresan, Eleonora Marian, Adina Negrea, and Otilia Micle Cell-to-Cell Crosstalk: A New Insight into Pulmonary Hypertension Yan Zhang and Yun Wang.
    Type of Medium: Online Resource
    Pages: V, 179 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031242045
    Series Statement: Reviews of Physiology, Biochemistry and Pharmacology, 184
    DDC: 612
    Language: English
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  • 23
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Agriculture. ; Environmental management. ; Food science. ; Ecology . ; Soil science. ; Agriculture. ; Environmental Management. ; Food Science. ; Ecology. ; Soil Science.
    Description / Table of Contents: Chapter 1: Introduction -- Chapter 2: History, origin, and geographical distribution of subterranean crops -- Chapter 3:What are the precise aspects of crop management, post-harvest technology, and key points of storage of subterranean crops? -- Chapter 4: A catalogue of field equipment used in the cultivation of subterranean crops -- Chapter 5: Subterranean crops and Starches -- Chapter 6: The role of post-harvest technology and value addition in subterranean crops -- Chapter 7: Global economic potential for value addition in subterranean crops -- Chapter 8: The role of bioprocessing in protein-enriched animal feed -- Chapter 9: Biotechnological potential and interventions in subterranean crops and some thoughts on the future course of research in these crops. .
    Abstract: Tropical root and tuber crops form an important group of food crops for millions of people (about one-fifth of the world population), especially those living in the tropical and sub-tropical zones. Tuber crops are the third important food crops after cereals and grain legumes. The carbohydrates synthesized in the leaves and stored in the form of starch in the underground roots and tubers, which are not only for food, but also a raw material for several industries. Among the many tuber crops available, only a few have been domesticated and widely cultivated for edible and industrial purposes. This book addresses the principal issues connected with selected tuber and root crops, their origin, global distribution, cultivation details, and their global commercial potential, vis-à-vis the end products made out of them (value addition). Among the crops, sweet potato, cassava, yams, colocasia, west Indian arrowroot, asparagus, safed musli, Indian Bread root and gloria superba will be discussed. From various projections, it is evident that by the year 2050 the world population will face a serious food shortage, if current trends in cereals consumption is taken intoaccount. That is why root and tuber crops assume great importance. Contrary to the high-fertility soils, which are a requirement for principal cereals like rice and wheat, root and tuber crops can grow quite well in poor soils, under varying climatic conditions. .
    Type of Medium: Online Resource
    Pages: XII, 131 p. 8 illus., 7 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031296468
    DDC: 630
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Pharmacology. ; Pharmacy. ; Career education. ; Pharmacology. ; Pharmacy. ; Career Skills.
    Description / Table of Contents: Fellowship 101 -- The First Professional Year (P1) -- The Second Professional Year (P2) -- The Third Professional Year (P3) -- The Fourth Professional Year (P4) -- Midyear Applications, Interviews, and Receptions -- Transitioning from Student to Fellow -- Navigating the Virtual Landscape.
    Abstract: For many Doctor of Pharmacy (PharmD) candidates, post-graduate training is a highly prestigious and sought after experience that can further one’s pre-existing education. Some of these post-graduate training opportunities include but are not limited to pharmacy residencies, pharmaceutical industry fellowships, and PhD/Masters programs. There is a large gap in the current Doctor of Pharmacy curriculum about pharmaceutical industry fellowship programs and potential pharmaceutical industry opportunities. Through the eyes of current industry fellows and professionals, this book serves as a resource to learn more about fellowship opportunities and their respective application processes. In addition, this manual aims to provide a clear and concise roadmap to achieving a career in industry through a fellowship program. Whether you are a current student pharmacist, post-graduate pharmacy trainee (pharmacy resident), or industry professional, this manual addresses the current landscape of industry fellowship programs, an overview of industry opportunities, and a glimpse into what being a fellow entails. Readers of this book can expect to gain: An overview of pharmaceutical industry fellowship programs and opportunities Helpful advice and insight from current fellows and industry professionals A streamlined pathway to navigating the fellowship application process An understanding of the journey from being a student, to achieving a fellowship, to becoming an industry professional This book bridges the gap in education surrounding pharmaceutical industry fellowships and pharmacy careers in industry and increases access to first-hand information and real-world perspectives of current professionals to provide a firm foundation for those interested in pursuing a career in industry or learning more about fellowship programs.
    Type of Medium: Online Resource
    Pages: XIX, 92 p. 4 illus., 3 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031357879
    Series Statement: SpringerBriefs in Pharmaceutical Science & Drug Development,
    DDC: 615
    Language: English
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  • 25
    Keywords: Cancer. ; Oncology. ; Medical screening. ; Cancer Treatment. ; Tumor markers. ; Cancer Biology. ; Oncology. ; Cancer Screening. ; Cancer Therapy. ; Tumour Biomarkers.
    Description / Table of Contents: Chapter 1. Introduction: The Application of AI in Precision Oncology: Tailoring Diagnosis, Treatment, and the Monitoring of Disease Progression to the Patient -- Part I. Artificial Intelligence for Screening, Diagnosis, Monitoring in Precision Oncology -- Chapter 2. Application of AI in Novel Biomarkers Detection that Induce Drug Resistance, Enhance Treatment Regimens and Advancing Precision Oncology -- Chapter 3. Use of Artificial Intelligence in Implementing Mainstream Precision Medicine to Improve Traditional Symptom-driven Practice of Medicine: Allowing Early Interventions and Tailoring better-personalized Cancer Treatments -- Chapter 4. AI as a Novel Approach for Exploring ccfNAs in Personalized Clinical Diagnosis and Prognosis: Providing Insight into the Decision-Making in Precision Oncology -- Chapter 5. AI-Enhanced Digital Pathology and Radiogenomics in Precision Oncology -- Part II. Artificial Intelligence and Omics in Precision Oncology -- Chapter 6. Epigenetics Analysis Using Artificial Intelligence in the Era of Precision Oncology -- Chapter 7. Association of Metabolomics with AI in Precision Oncology: Emerging Perspectives for More Effective Cancer Care -- Chapter 8. Artificial Intelligence Application to Microbiomics Data for Improved Clinical Decision Making in Precision Oncology -- Part III. Artificial Intelligence in Cancer Therapy and the Clinical Applications -- Chapter 9. AI and Nanotechnology in Realizing the Goal of Precision Medicine: Tailoring the Best Treatment for Personalized Cancer Treatment -- Chapter 10. Artificial Intelligence-Based Medical Devices Revolution in Cancer Screening: Impact into Clinical Practice -- Chapter 11. Intelligent Drug Design and Use for Cancer Treatment: The Roles of AI and Precision Oncology in Targeting Patient-Specific Splicing Profiles -- Chapter 12. Applying Artificial Intelligence Prediction Tools for Advancing Precision Oncology in Immunotherapy: Future Perspectives in Personalized Care -- Chapter 13. Employing AI-Powered Decision Support Systems in Recommending the Most Effective Therapeutic Approaches for Individual Cancer Patients: Maximizing Therapeutic Efficacy -- Chapter 14. AI-Pathway Companion in Clinical Decision Support: Enabling Personalized and Standardized Care Along Care Pathways in Oncology -- Chapter 15. AI Tools Offering Cancer Clinical Applications for Risk Predictor, Early Detection, Diagnosis, and Accurate Prognosis: Perspectives in Personalised Care -- Chapter 16. Conclusion and Insights into the Future of AI in Precision Oncology.
    Abstract: This book highlights the use of artificial intelligence (AI), big data and precision oncology for medical decision making in cancer screening, diagnosis, prognosis and treatment. Precision oncology has long been thought of as ideal for the management and treatment of cancer. This strategy promises to revolutionize the treatment, control, and prevention of cancer by tailoring tests, treatments and predictions to specific individuals or population groups. In order to accomplish these goals, vast amounts of patient or population group specific data needs to be integrated and analysed to be able to identify key patterns or features which can be used to define or characterize the disease or the response to the disease in these individuals. These patterns or features can be as varied as molecular patterns or features in medical images. This level of data analysis and integration can only be achieved through the use of AI. The book is divided into three parts starting with a section on the use of artificial intelligence for screening, diagnosis and monitoring in precision oncology. The second part: Artificial intelligence and Omics in precision oncology, highlights the use of AI and epigenetics, metabolomics, microbiomics in precision oncology. The third part covers artificial intelligence in cancer therapy and its clinical applications. It also highlights the use of AI tools for risk prediction, early detection, diagnosis and accurate prognosis. This book, written by experts in the field from academia and industry, will appeal to cancer researchers, clinical oncologists, pathologists, medical students, academic teaching staff and medical residents interested in cancer research as well as those specialising as clinical oncologists.
    Type of Medium: Online Resource
    Pages: XIV, 315 p. 64 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031215063
    DDC: 571.978
    Language: English
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    Keywords: Virology. ; Medicine Research. ; Biology Research. ; Virology. ; Biomedical Research.
    Description / Table of Contents: 1. RNAi: The Mosquito Defense System Against Damage Due to Arbovirus Infection -- 2. A First-hand Account of the Progression of Flavivirus Molecular Biology -- 3. Sindbis Virus: Studies of Alphavirus Pathogenesis -- 4. Mechanisms of Tick-borne Virus Transmission -- 5. The Use of Humanized Mice to Understand Arbovirus Pathogenesis -- 6. Molecular Biology of Arboviruses -- 7. Mosquito-Virus-Environment Interactions -- 8. A Brief Historical Overview of the Discovery of Arboviruses in the USSR and Russia -- 9. The History of the Emergence of La Crosse Encephalitis Virus in the Driftless Area of the United States: A Mosquito Runs Through It! -- 10. “It Isn’t Going to Reach Here”: Venezuelan Equine Encephalitis in Texas, 1971 -- 11. History of Arbovirology in Canada -- 12. Arbovirus Discovery in the British Empire: India and Africa, c. 1880-1960 -- 13. History of Arbovirology in Japan -- 14. Ockelbo Disease in Sweden: Unraveling the Epidemiology, Ecology, and Evolution of Sindbis Virus -- 15. Human Arboviruses in Eastern, South-Eastern, and Southern Asia: A Brief History of Their Isolation and Characteristics -- 16. History of Arbovirus Research in Kenya -- 17. Vector Studies in the Amazon Basin Region of Peru -- 18. Zika Virus Studies in West Africa -- 19. Hemorrhagic Fevers -- 20. Chronicles of Hantaviruses: Virus Discovery to Vaccine Candidates -- 21. A History of Tick-Borne Encephalitis and Its Virus -- 22. Kyasanur Forest Disease -- 23. The Discovery of Insect-Specific Viruses in Australia: Mossies, Old Mates, and New Methods.
    Abstract: These books bring together a panel of expert arbovirologists who recall the history of arbovirology from very personal perspectives. In these timely volumes, the authors describe seminal moments in their experiences in the field and how they integrated these findings with lab studies to further clarify the ecology and epidemiology of diverse arboviruses. Authors identify the most pressing questions that remain to be answered, providing a basis for current research and a stimulus to engage those entering the field. Over the last 20 years a generational gap has developed between the giants of arbovirus research and discovery and the new generation. This gap developed due to an ebbing of training and investment in passing the scepter to the next generation, leading to a lack of continuity among the generations that threatens to derail the rich history of virus discovery, field epidemiology and understanding of the richness of diversity that surrounds us. This lack of continuity may have immediate and disastrous consequences for public health when yet to be discovered arboviruses emerge. The purpose of these books is to bridge this gap by providing a historical context for the work being done today and provide continuity between the generations. To this end, the books provide a narrative of the thrill of scientific discovery and excitement of field adventures and lab studies of that generation -- essential reading for every arbovirologist, and highly recommended for all virologists and public health officials, as well as those students considering future research options. Volume I consists of the personal reflections of arbovirologists who played a significant role in the advancement of arbovirology across the globe. Volume II transitions to descriptions of region-specific and virus family-specific perspectives of arbovirology, as well as recollections of the early events of molecular advances and pathogenesis studies.
    Type of Medium: Online Resource
    Pages: XX, 530 p. 171 illus., 121 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031220036
    DDC: 579.2
    Language: English
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    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Human physiology. ; Endocrine glands. ; Metabolism. ; Neurosciences. ; Human Physiology. ; Endocrine System. ; Metabolism. ; Neuroscience.
    Description / Table of Contents: Patch Clamp: The First Four Decades of a Technique That Revolutionized Electrophysiology and Beyond -- Roles of Intramolecular Interactions in the Regulation of TRP Channels -- The Emerging Pro-Algesic Profile of Transient Receptor Potential Vanilloid Type 4 -- Role of Oxytocin in Different Neuropsychiatric, Neurodegenerative, and Neurodevelopmental Disorders -- Role of Distinct Fat Depots in Metabolic Regulation and Pathological Implications -- Autocrine, Paracrine, and Endocrine Signals That Can Alter Alveolar Macrophages Function.
    Abstract: Patch Clamp: The First Four Decades of a Technique That Revolutionized Electrophysiology and Beyond Davide Lovisolo Roles of Intramolecular Interactions in the Regulation of TRP Channels Ruiqi Cai and Xing-Zhen Chen The Emerging Pro-Algesic Profile of Transient Receptor Potential Vanilloid Type 4 John P. M. White, Mario Cibelli, Istvan Nagy, Bernd Nilius, and James Graham McGeown Role of Oxytocin in Different Neuropsychiatric, Neurodegenerative, and Neurodevelopmental Disorders Aya A. Ghazy, Omar A. Soliman, Aya I. Elbahnasi, Aya Y. Alawy, Amira Ma Mansour, and Mennatallah A. Gowayed Role of Distinct Fat Depots in Metabolic Regulation and Pathological Implications Bijayashree Sahu, Ojas Tikoo, Benudhara Pati, Unmod Senapati, and Naresh C. Bal Autocrine, Paracrine, and Endocrine Signals That Can Alter Alveolar Macrophages Function Yue Yang and Yun Wang.
    Type of Medium: Online Resource
    Pages: VII, 198 p. 24 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031256288
    Series Statement: Reviews of Physiology, Biochemistry and Pharmacology, 186
    DDC: 612
    Language: English
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    Cham :Springer Nature Switzerland :
    Keywords: Biologicals. ; Biopharmaceutics. ; Pharmaceutical chemistry. ; Pharmacy. ; Biologics. ; Pharmaceutics. ; Pharmacy.
    Description / Table of Contents: Biopharmaceutical Landscape -- Regulatory Pathways Impacting Biopharmaceuticals -- Differences in CMC Regulatory Compliance: Biopharmaceuticals Versus Chemical Drugs -- Risk Management of the Minimum CMC Regulatory Compliance Continuum -- Ever-Present Threat of Adventitious Agent Contamination -- Starting Materials for Manufacturing the Biopharmaceutical Drug Substance -- Upstream Production of the Biopharmaceutical Drug Substance -- Downstream Purification of the Biopharmaceutical Drug Substance -- Manufacturing the Biopharmaceutical Drug Product -- Complex Process-Related Impurity Profiles -- Seemingly Endless Biomolecular Structural Variants -- Indispensable Potency (Biological Activity) -- Biopharmaceutical Critical Quality Attributes -- The Art of Setting Biopharmaceutical Specifications – Release and Shelf-Life -- The Challenge of Demonstrating Biopharmaceutical Product Comparability -- Strategic CMC-Focused Interactions with Regulatory Authorities.
    Abstract: Each year for the past three years, there have been about 50 new molecular medicines approved by the United States Food & Drug Administration (FDA), of which approximately 25% were new biopharmaceuticals. Over 200 recombinant proteins, monoclonal antibodies, antibody drug conjugates, fusion proteins, and Fab fragments are now in the marketplace in both the United States of America (USA) and European Union (EU). There are also now over 60 biosimilars available for all major classes of recombinant proteins and monoclonal antibodies. In addition, gene therapies using genetically engineered viruses and genetically engineered cells are now in the marketplace, and continually growing. This degree of change is reflected in the over 400 CMC regulatory compliance references listed in this book that were either issued or updated since the release of the third edition. Deficiencies in biopharmaceutical CMC regulatory compliance rarely result in termination of a product, but in can readily cause months if not years of delay in initiating clinical trials, or advancing clinical development stages, or even market approval. In summary, this book: Updates real-world CMC deficiency examples with current examples; Addresses current FDA and EMA requirements and expectations for CMC regulatory compliance; Now includes CMC regulatory compliance for the new gene-based biopharmaceuticals.
    Type of Medium: Online Resource
    Pages: XXXV, 573 p. 1 illus. , online resource.
    Edition: 4th ed. 2023.
    ISBN: 9783031319099
    DDC: 615.7
    Language: English
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    Cham :Springer Nature Switzerland :
    Keywords: Pharmaceutical chemistry. ; Pharmacology. ; Pharmacy. ; Pharmacovigilance. ; Pharmaceutics. ; Pharmacology. ; Pharmacy. ; Drug Safety and Pharmacovigilance.
    Description / Table of Contents: Part I: Physical properties of solids -- Part II: Mixing -- Rapid Mixer Granulator -- Fluid bed processing technology -- Drying -- Compression -- Pan coating -- Size reduction -- Part III: Mixing and filtration -- Scale-up of liquid mixing process -- Manufacturing process of nanoparticles -- Scale-up of nanoparticle manufacturing process -- Part 4: Manufacturing and scale-up of biotechnology-derived products. .
    Abstract: The book offers a comprehensive overview of the unit operations involved in the manufacturing process of solid and liquid dosage forms, along with the scale-up of each operation. This book is a valuable resource for professionals working in the pharmaceutical industry and researchers seeking to develop a comprehensive understanding of the various aspects of the manufacturing process. The book is divided into four sections, covering a range of topics. Section I provide readers with a comprehensive understanding of the basic principles behind the manufacturing process of solid and liquid dosage forms. Section II covers the different unit operations involved in the production of solid dosage forms, including mixing, granulation, drying, compression, coating, and size reduction. This section includes case studies to provide readers with practical insights into the scale-up principles involved in the manufacturing process. Section III focuses on the manufacturing and scale-up of liquid formulations, covering topics such as mixing, filtration, and scale-up of liquid mixing process. This section offers a comprehensive understanding of the various aspects of the manufacturing process, including the challenges and opportunities associated with the scale-up of liquid formulations. Finally, Section IV includes two chapters that describe the manufacturing and scale-up of advanced drug delivery systems, including the manufacturing and scale-up of nanoparticles and biotechnology-derived products. This section provides readers with insights into the development of innovative drug delivery systems and the challenges involved in their scale-up. Overall, the book is an essential guide for professionals and researchers seeking a deeper understanding of the manufacturing process. The case studies and practical examples offer valuable insights into the challenges and opportunities involved in the scale-up process, making it an indispensable resource for those involved in the pharmaceutical industry. Only book that is dedicated to pharmaceutical process engineering and scale-up; Contain numerous case studies for easy reference; Covers solid, liquid, and advanced dosage forms.
    Type of Medium: Online Resource
    Pages: XX, 218 p. 49 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031313806
    Series Statement: AAPS Introductions in the Pharmaceutical Sciences, 13
    DDC: 615.19
    Language: English
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    Cham :Springer Nature Switzerland :
    Keywords: Cancer. ; Cancer Treatment. ; Stem cells. ; Cytology. ; Medical genetics. ; Immunology. ; Cancer Biology. ; Cancer Therapy. ; Cancer Stem Cells. ; Cell Biology. ; Medical Genetics. ; Immunology.
    Description / Table of Contents: Interdisciplinary Approaches in Cancer Research -- Role of Immune Cells in the Tumor Microenvironment -- Spatial Transcriptomic Approaches for Understanding the Tumor Microenvironment (TME) -- Role of Mesenchymal Stem/Stromal Cells in Cancer Development -- Cancer-associated Fibroblasts and Their Role in Cancer Progression -- The Role of Tumoroids in Cancer Research -- Myokines Expression in Cancer Cachexia -- Epigenetics in Cancer Biology -- Epigenetic Regulation of Cancer by Natural Touch: Phytochemicals and Epigenetic Regulation -- Telomerase Reverse Transcriptase in Humans: From Biology to Cancer Immunity -- Molecular Mechanisms of Metal-induced Carcinogenesis -- Epi-drugs Targeting RNA Dynamics in Cancer -- Oncologic Emergencies: Pathophysiology, Diagnosis, and Initial Management -- Malignancies in Inborn Errors of Immunity -- Hematopoietic Stem Cell Transplantation in Patients with Inborn Errors of Immunity and Malignancy -- Personalized Immuno-oncology with Immunodeficiency Mouse Models -- Allergy and Cancer: New Perspectives -- Depression and Cancer: the Inflammatory Bridge -- Impact of Cancer-Related Sarcopenia on Systemic Immune Status -- Surveillance of Subclinical Cardiovascular Complications in Childhood Cancer Survivors: Exercise as a Diagnostic and Therapeutic Modality.
    Abstract: Cancer is a major public health concern and one of the leading causes of death. There is no simple solution for this complex disease, therefore interdisciplinary approaches might help to find solutions to many unanswered questions and challenges about cancer. The rapid flow of interdisciplinary research in cancer during recent years has increased our understanding of the nature of cancers. Such interdisciplinary approaches could be helpful for both the diagnosis and the development of more effective therapeutic strategies. The “Interdisciplinary Cancer Research” series publishes comprehensive volumes on different cancers and presents the most updated and peer-reviewed articles on human cancers. Over the past decade, increased cancer research has greatly improved our understanding of the nature of cancerous cells which has led to the development of more effective therapeutic strategies to treat cancers. This interdisciplinary series is of special value to researchers and practitioners working on cell biology, immunology, hematology, biochemistry, genetics, oncology and related fields. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN).
    Type of Medium: Online Resource
    Pages: XI, 611 p. 31 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031324581
    Series Statement: Interdisciplinary Cancer Research, 1
    DDC: 571.978
    Language: English
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    Keywords: Biomedical engineering. ; Biotechnology. ; Agricultural biotechnology. ; Sustainability. ; Industrial microbiology. ; Biomedical Engineering and Bioengineering. ; Biotechnology. ; Agricultural Biotechnology. ; Sustainability. ; Industrial Microbiology.
    Description / Table of Contents: Part 1: Food and sustainable agriculture -- Chapter 1. Mycotoxin Occurrence and Risk Assessment in Infants and Young Children (IYC) Formulated Foods in Southwest Nigeria -- Chapter 2. In vitro antifungal activity of Bauhinia monandra (kurz) leaf extracts against fungal pathogens isolated from spoilt Musa paradisiaca l -- Chapter 3. Effect of Aspergillus fumigatus MT899185 phytase addition on the nutritional and phytate content of formulated cowpea-based poultry feed -- Chapter 4. Histology, Condition Factor, and DNA Analysis of Clarias gariepinus (Burchell, 1822) Exposed to MC-LR -- Chapter 5. Morphological trait variation and correlation analysis in landraces of southern Nigerian fluted pumpkin (Telfairia occidentalis Hook. F.) -- Part 2: Climate change and the environment -- Chapter 6. Comparative Analysis of the Trophic status, Length-Weight Relationship, Gastrosomatic Index and Bioaccumulation of Trace Metals in Wild and Captive Clarias gariepinus -- Chapter 7. Occurrence and Characteristics of Microplastics in the Surface Water and Sediment of Lagos Lagoon, Nigeria -- Chapter 8. Assessment of the Effectiveness of Chlorination for Drinking Water Treatment -- Part 3: Health pandemic and biotechnology -- Chapter 9. Lack of Association of CYP2C9:c.430C〉T and SCN1A:c.3184A〉G polymorphisms with Epilepsy risk or Drug-resistance in Childhood Epilepsy Syndromes in Lagos State, Nigeria -- Chapter 10. Computational Approaches Towards Prevention And Surveillance of Lassa Fever In Developing Countries -- Chapter 11. Antibacterial Efficacy of Thymus vulgaris Essential Oil Against Extended Spectrum Betalactamase - Producing Escherichia Coli In Urinary Tract Infections -- Chapter 12. Antibacterial efficacy of Syzygium aromaticum essential oil against extended spectrum Betalactamase -producing Escherichia Coli in urinary tract infections -- Chapter 13. Growth And Haemato-Biochemical Responses Of All-Male Tilapia, Oreochromis niloticus To Diets Containing Fermented Cassava Leaf Meal -- Chapter 14. Implication of age-demography of Mycobacterium tuberculosis infection among HIV seropositive and seronegative individuals -- Chapter 15. Comparative phytochemical contents and antioxidant activities of Tapinanthus cordifolius and Irvingia wombolu leaf extracts -- Chapter 16. The central metabolism model of Anopheles gambiae: a tool for understanding malaria vector biology -- Part 4: Biotechnology For Sustainable Economy -- Chapter 17. Plant Microbiome Engineering: Principles, Methods, and Current Trends -- Chapter 18. Water Purification Potentials of Crustacean Chitosan -- Part 5: Industrial Biotechnology and SDGS -- Chapter 19. Omics and Mutagenesis: Molecular Optimization Strategies For Strain Improvement In Biosurfactants Production -- Chapter 20. Comparison Of Two Extraction Methods To Obtain Quality Genomic DNA From Eggplants (Solanum Sp.).
    Abstract: Biotechnological Approaches to Sustainable Development Goals presents selected contributions from the 2022 International Biotechnology Conference Exhibition and Workshop (IBCEW) that cover techniques, current trends, and cutting-edge biotechnological tools for achieving sustainable development goals (SDGs). The authors explore recent advances that solve challenges related to sustainable agriculture, climate change, prevention and control of pandemics, biotechnology for a sustainable economy, and biotechnological industries and SDGs. The IBCEW aims to share knowledge, experiences, and ideas among scientists, academics, students, industry representatives, and other professionals interested in biotechnology and attaining SDGs for development in Nigeria, Africa, and globally. Examines health and environmental sustainability challenges in Africa and globally; Introduces biotechnological tools for achieving sustainable development goals; Includes contributions from scientists, academics, and industry representatives.
    Type of Medium: Online Resource
    Pages: XIX, 318 p. 61 illus., 50 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031333705
    DDC: 610.28
    Language: English
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    Cham :Springer Nature Switzerland :
    Keywords: Biodiversity. ; Agriculture. ; Soil science. ; Pollution. ; Sustainability. ; Food science. ; Biodiversity. ; Agriculture. ; Soil Science. ; Pollution. ; Sustainability. ; Food Science.
    Description / Table of Contents: Chapter 1: Introduction -- Chapter 2: Agrobiodiversity -- Chapter 3: Biodiversity of the Pedosphere -- Chapter 4: Chemosynthesis-based community biodiversity -- Chapter 5: What are the threats to biodiversity? Its conservation and sustainability. .
    Abstract: This book begins with the principal subject of biodiversity in agriculture. The onslaught of highly soil extractive chemical farming, euphemistically called the “green revolution”, has taken a heavy toll on soil biodiversity, hence, soil sustenance. Agrobiodiversity is a key resource for humanity. All of the food requirements humanity depends on are met by agrobiodiversity. Similarly, fodder fiber, firewood, and many other basic needs of humankind are also met by agrobiodiversity. The book puts forward ideas on how we are to develop a sustainable future, to provide a healthy and thriving environment for humanity by protecting, conserving, and augmenting agrobiodiversity. The pedosphere, the outermost layer of the Earth, composed of soil and subject to soil formation processes, is an integral component of biosphere, lying on the interface of the atmosphere, hydrosphere, and lithosphere and a lot more complex in its physicochemical and biological characteristics and functioning and quite distinguishable from that of the above soil-surface terrestrial and aquatic ecosystems. The biotic component of the pedosphere comprises a rich biodiversity of living species, dominated by microorganisms. This book considers and discusses the influences of soil formation processes. This book will be of interest to those engaged in researching biodiversity, agriculture, and crop science.
    Type of Medium: Online Resource
    Pages: XIII, 100 p. 6 illus., 4 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031442520
    DDC: 333.95
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    Keywords: Biology. ; Anatomy. ; Developmental biology. ; Biological Sciences. ; Anatomy. ; Developmental Biology and Stem Cells.
    Description / Table of Contents: 1 Carotid Body: The Primary Peripheral Arterial Chemoreceptor -- 2 History and Recent Progress in Carotid Body Studies -- 3 General Morphology of the Mammalian Carotid Body -- 4 Structural Plasticity of Carotid Bodies -- 5 Mechanisms of Chemosensory Transduction at the Carotid Body -- 6 Neurochemical Anatomy of the Mammalian Carotid Body -- 7 Neurochemical Plasticity of Carotid Bodies -- 8 Carotid Body Dysfunction and Mechanisms of Disease -- 9 Stem Cell Niche in the Mammalian Carotid Body -- 10 Carotid Body and Cell Therapy -- 11 The Carotid Body: a Tiny Structure with Many Roles.
    Abstract: This new volume of the book series Advances in Anatomy, Embryology and Cell Biology provides a complete and exhaustive overview of the morphofunctional organization of the mammalian carotid body, a polymodal chemosensory organ responsible for the maintenance of blood gas homeostasis. The authors review the state of the art of the neurochemical anatomy of carotid body´s cell populations with a special reference to their structural and neurochemical plasticity. The essential role of this organ in the generation, progression and maintenance of cardiorespiratory and metabolic diseases in humans and other mammals is presented. Finally, the book summarizes current knowledge on the stem cell niche in the mammalian carotid body and discusses its contribution to replacement cell therapy and other potential applications in translational research. This book represents an essential reading for physiologists, anatomists, cell, and developmental biologists, as well as physicians, veterinarians, and biomedical researchers.
    Type of Medium: Online Resource
    Pages: XIV, 165 p. 47 illus., 42 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031447570
    Series Statement: Advances in Anatomy, Embryology and Cell Biology, 237
    DDC: 570
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    Cham :Springer Nature Switzerland :
    Keywords: Nanobiotechnology. ; Medicinal chemistry. ; Catalysis. ; Nanobiotechnology. ; Medicinal Chemistry. ; Catalysis.
    Description / Table of Contents: Chapter 1 Nano cerium oxide in medicine, agriculture and the industry -- Chapter 2 Synthesis and sensing applications of peroxidase-mimic nanozyme -- Chapter 3 Nanozymes for glucose sensing and diabetes management -- Chapter 4 Nanozymes for bioimaging and disease diagnostics -- Chapter 5 Nanozymes for improving anticancer therapy -- Chapter 6 Enzyme-based nanomedicine for cancer therapy -- Chapter 7. Synthesis of two-dimensional metal, metal oxide and metal hydroxide nanomaterials for biosensing -- Chapter 8 Biological applications of nanozymes.
    Abstract: This book reviews the latest advances and biomedical applications of nanozymes, which are artificial nanomaterials exhibiting enzymatic properties similar to natural enzymes, but with less limitations than natural enzymes. Nanozymes display advantages such as facile synthesis, easy surface modification, improved stability, higher catalytic power, and target-specific binding. Nanozymes containing metals, metal oxides, carbon, and metal sulfide are actually used for cancer therapy, biomolecules sensing, bioimaging, disease diagnostics and diabetes management. The book discloses underlying mechanisms, concepts, recent trends, constraints, and prospects for nanomedicine using nanozymes.
    Type of Medium: Online Resource
    Pages: XV, 212 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031205811
    Series Statement: Environmental Chemistry for a Sustainable World, 72
    DDC: 620.5
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    Keywords: Food science. ; Agricultural biotechnology. ; Agriculture Economic aspects. ; Nanotechnology. ; Food Engineering. ; Agricultural Biotechnology. ; Agricultural Economics. ; Nanoengineering.
    Description / Table of Contents: Technical Correctness of Sprayer Nozzles for Pesticides Application in Bosnia and Herzegovina -- Determination of Water Extractable Chloride in the Greenhouse Soil and Minimizing Interferences Caused by the Presence of the Iron Ions -- Detection of Blueberry Latent Virus on Highbush Blueberries in Montenegro -- Leaf Diseases of Wild Barley (Hordeum spontaneum) in Bingöl University Campus, Turkey -- The Effect of Biofertilization on Potato Yield Components -- Effects of Mulching and Irrigation on Antioxidant Activity and Antimicrobial Properties of Basil (Ocimum basilicum L.) -- Impact of Climate Change on the Soil Water Balance Components in the Area of Sanski Most (Bosnia and Herzegovina).
    Abstract: This book gathers the proceedings of the 32nd Scientific-Experts Conference of Agriculture and Food Industry, held on December 1-2, 2022, in Sarajevo, Bosnia and Herzegovina. It reports on the application of molecular, nano- and engineering technologies for food sciences, and plant and animal production. It discusses important agricultural economics and social and environmental issues, proposings some answers to current and future challenges. The chapters reflect the special focus of this conference edition, which was on discussing strategies for developing a more resilient and sustainable agrifood systems. Offering a timely snapshot of cutting-edge and multidisciplinary research and methods, this book addresses researchers, professionals, and stakeholders in the broad field of agriculture and food sciences, biotechnology, and bio- and nanoengineering. .
    Type of Medium: Online Resource
    Pages: X, 424 p. 93 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031474675
    Series Statement: Lecture Notes in Bioengineering,
    DDC: 664
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    Keywords: Cytology. ; Stem cells. ; Regenerative medicine. ; Molecular biology. ; Epigenetics. ; Cell Biology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering. ; Molecular Biology. ; Epigenetics.
    Description / Table of Contents: Mitochondrial Permeability Transition in Stem Cells, Development, and Disease -- HSF1, Aging, and Neurodegeneration -- Pathophysiology of Spinal Cord Injury and Tissue Engineering Approach for Its Neuronal Regeneration: Current Status and Future Prospects -- Application of Biocompatible Scaffolds in Stem-Cell-Based Dental Tissue Engineering -- Therapeutic Perspectives for the Clinical Application of Umbilical Cord Hematopoietic and Mesenchymal Stem Cells: Overcoming Complications Arising After Allogeneic Hematopoietic Stem Cell Transplantation -- Advanced Nanotechnology Approaches as Emerging Tools in Cellular-Based Technologies -- Generation of a Beta-Cell Transplant Animal Model of Diabetes Using CRISPR Technology -- The Link Between Heat Shock Proteins, Renin-Angiotensin System, and the Coagulation Cascade in the Pathogenesis of the Coronavirus-19 Disease -- Aptamer-Based Tumor-Targeted Diagnosis and Drug Delivery -- Heat Shock Proteins: Central Players in Oncological and Immuno-Oncological Tracks.
    Abstract: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of Springer Nature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the 18th volume of a continuing series.
    Type of Medium: Online Resource
    Pages: VIII, 207 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031284243
    Series Statement: Cell Biology and Translational Medicine, 1409
    DDC: 571.6
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    Keywords: Paleoecology. ; Paleontology . ; Bioinformatics. ; Archaeology. ; Earth sciences. ; Paleoecology. ; Paleontology. ; Computational and Systems Biology. ; Archaeology. ; Earth Sciences.
    Description / Table of Contents: Chapter1. Introduction to Indian Late Cretaceous-Early Palaeocene Microbiota from the Deccan Intertrappean Beds of the Chhindwara District, Madhya Pradesh, India -- Chapter 2. Historical Background of Late Cretaceous-Early Palaeocene Microbiotic Assemblages from the Deccan Intertrappean Beds of the Chhindwara District, Madhya Pradesh, India -- Chapter 3. Geology and Stratigraphy of Microbiota-Bearing Deccan Intertrappean Beds of the Chhindwara District, Madhya Pradesh, India -- Chapter 4. Indian Late Cretaceous-Early Palaeocene Deccan Microbiota from Chhindwara District, Madhya Pradesh: Systematic Studies -- Chapter 5 Palaeoecological and Palaeoenvironmental Implications of the Cretaceous-Palaeogene Microbiota-Bearing Deccan Intertrappean beds of the Chhindwara District, Madhya Pradesh, India -- Chapter 6. Palaeobiogeographical Implications of Late Cretaceous-Early Palaeocene Microbiota from the Deccan Intertrappean beds of the Chhhindwara District, Madhya Pradesh, India.
    Abstract: This book describes the microbiota of the intertrappean beds in the Chhindwara District, Madhya Pradesh, India. In this work, special emphasis is placed on the microbiota from the Late Cretaceous-Early Palaeocene transition of the central Narmada River region. Recently, the intertrappean beds of the Eastern Deccan Volcanic Province (one of the subprovinces of the Deccan Volcanic Province) have received considerable attention, which resulted in the addition of some significant biotic assemblages to the existing record from the Dindori-Chhindwara area of the province. The biotic assemblages include charophytes, ostracods, foraminiferans, fishes, frogs, lizards, turtles, crocodiles, and mammals. In spite of the recent discoveries, the known fossil record of the Late Cretaceous-Early Palaeocene biota of India is not sufficient and thus does not permit us to speculate on the possible impact of environmental changes triggered by the Deccan volcanic lava flows on the contemporary biota and to precisely document their palaeoecologic, palaeoenvironmental and palaeobiogeographic implications. The recent biotic reports from the intertrappean beds exposed in the Chhindwara region of the Eastern Deccan Volcanic Province clearly indicate that these beds have a vast potential in terms of fossil content, which could reveal new and dissimilar biotic remains when compared to the Western Deccan Volcanic Province. The record of diverse accumulations of freshwater charophytes, brackish to freshwater ostracods, and planktic foraminiferal and fish assemblages from the intertrappean beds of Jhilmili and adjacent areas of Early Danian (P1a) age and lying just north of Chhindwara town and in the heart of peninsular India has intriguing implications for defining the age limits of the basaltic flows. The occurrence of non-marine taxa, for example, algae, molluscs, and vertebrates, associated with brackish water ostracods in the nearby Singpur and Mohgaon Kalan localities of the Chhindwara region, has also raised concerns about the sedimentary environments of these intertrappean beds. The new finds (presented in this book) prove useful for the better understanding of the palaeoecology and palaeoenvironment of the biota and also throw light on various paleobiogeographic models proposed for the northward drifting Indian plate. The microbiotic assemblages of the intertrappean beds of the eastern Deccan volcanic province at District Chhindwara, Madhya Pradesh are documented in this book. The microbiota of the central Narmada River region, the charophytes, ostracods, planktic foraminifera, and fishes, receive special attention in this study.
    Type of Medium: Online Resource
    Pages: XXIII, 274 p. 55 illus., 36 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031288555
    Series Statement: Topics in Geobiology ; 54
    DDC: 560.45
    Language: English
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    Cham :Springer Nature Switzerland :
    Keywords: Molecular biology. ; Cytology. ; Immunology. ; Cancer. ; Pathology. ; Neurosciences. ; Molecular Biology. ; Cell Biology. ; Immunology. ; Cancer Biology. ; Pathology. ; Neuroscience.
    Description / Table of Contents: SECTION 1: Molecular pathology of immune, inflammatory, and hemostatic disorders -- Immune responses at host barriers and their importance in systemic autoimmune diseases -- Statins and hemostasis: therapeutic potential based on clinical evidence -- Effects of adrenergic receptor stimulation on human hemostasis: A systematic review -- α1-adrenergic stimulation increases platelet adhesion to endothelial cells mediated by TRPC6 -- Physical Activity, Burnout, and Engagement in Latin American Students of Higher Education during the COVID-19 Pandemic -- Small plastics, big inflammatory problems -- Impact of a community-based pelvic floor kinesic rehabilitation program on the quality of life of Chilean adult women with urinary incontinence -- SECTION 2: Molecular pathology of endocrine and muscular disorders -- Iodine intake based on a survey from a cohort of women at their third trimester of pregnancy from the Bosque County Chile -- Appraisal of the neuroprotective effect of dexmedetomidine: a meta-analysis -- Bile acids alter the autophagy and mitogenesis in skeletal muscle cells -- Upregulation of CCL5/RANTES gene expression in the diaphragm of mice with cholestatic liver disease -- Differential fibrotic response of muscle fibroblasts, myoblasts, and myotubes to cholic and deoxycholic acids -- BMAL1 regulates glucokinase expression through E-box elements in vitro -- SECTION 3: Molecular pathology of cancer: determinants and potential therapies -- Correlation between endoglin and malignant phenotype in human melanoma cells: analysis of hsa-mir-214 and hsa-mir-370 in cells and their extracellular vesicles -- Increase in Frequency of Myeloid-Derived Suppressor Cells in the Bone Marrow of Myeloproliferative Neoplasm: Potential Implications in Myelofibrosis -- The “Ins and Outs” of prostate specific membrane antigen (PSMA) as specific target in prostate cancer therapy -- Transforming Growth Factor-β1 in Cancer Immunology: opportunities for immunotherapy.
    Abstract: The present work corresponds to a compilation of independent contributions in the fields of endocrinology, immunity, cancer, neurobiology, and myology. Revision of current advances as well as novel findings in the form of original articles are presented in a balanced fashion. The book has been divided into three sections in line with the main subject: Molecular pathology of immune, inflammatory, and hemostatic disorders; Molecular pathology of endocrine and muscular disorders; and Molecular pathology of cancer: determinants and potential therapies. In the first section, contributing authors take the reader through the molecular pathology of immune responses, inflammation, and hemostasis, by collating an update on systemic autoimmune diseases, the therapeutic potential of statins in hemostasis, the effects of adrenergic stimulation on coagulation, the emerging field of physical burnout due to the mobility restrictions in response to the 2020 SARS-CoV-2 pandemic imposed worldwide, and the success of community-oriented muscular kinesic rehabilitation. The second section presents engaging results from a survey of iodine intake through the diet of pregnant females, an appraisal of the neuroprotective effect of dexmedetomidine, novel evidence on muscle physiopathology, describing the upregulation of CCL5/RANTES during cholestatic liver disease, the fibrotic response emerging in response to cholic and deoxycholic acids, and the altering effects of bile acids in autophagy and mitogenesis. In the third section, a comprehensive revision of cancer literature is offered with an emphasis on melanoma, myeloid-derived suppressor cells, microRNA-based diagnostic approaches, and new avenues for cancer immunotherapy. Altogether, these individual contributions offer a comprehensive and up-to-date outlook of the current state in the field of molecular pathology. Chapter 14 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: XVIII, 330 p. 72 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031261633
    Series Statement: Advances in Experimental Medicine and Biology, 1408
    DDC: 572
    Language: English
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  • 39
    Keywords: Agriculture. ; Nutrition   . ; Animal biotechnology. ; Agriculture. ; Nutrition. ; Animal Biotechnology.
    Description / Table of Contents: Chapter 1. Reproductive biotechnologies applied to the female sheep and goat -- Chapter 2. Oogenesis and folliculogenesis -- Chapter 3 Proteomics of animal viruses -- Chapter 4. Influence of the ovarian reserve and oocyte quality on livestock fertility -- Chapter 5. Metabolomics of food systems -- Chapter 6. Phytobioactive compounds on ovarian functions in mammals -- Chapter 7. Buffalo embryo production.
    Abstract: The dependency on animal biotechnology in livestock industries has been increased in the recent past. The livestock production research has witnessed remarkable developments on biotechnological methods to produce the elite animal breeds. The global animal food requirement has been steadily increasing, and animal production needs to be increased as per the global needs. This book covers various aspects of animal biotechnology such as, reproductive biotechnologies in sheep and goats, oogenesis and folliculogenesis and ovarian disorders. This book focusses the discussion on proteomics and metabolomics, and separate chapters were dedicated to discuss these topics. The proteomics studies of animal viruses were discussed in this book, and this would be helpful to understand animal viral pathogenesis. The applications of metabolomics in livestock were discussed with focus on data analysis, identification of unknown compounds. The purpose of this book is to provide the recent research trends, and convert all this information to usable guide to professionals, researchers and students who are working the research area of animal biotechnology. .
    Type of Medium: Online Resource
    Pages: XV, 322 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031216305
    Series Statement: Sustainable Agriculture Reviews, 59
    DDC: 630
    Language: English
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  • 40
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Biology. ; Biological Sciences.
    Description / Table of Contents: (1) Should I Eat Meat? -- (2) Meat and the Environment: How Livestock are Taking a Big Bite Out of Our Planet -- (3) An Ethical Dilemma: To Meat or Not to Meat? -- (4) Meat and Nutrition: Will Eating Less Meat Make Me Healthier? -- (5) Staying Alive: Is a Meat-Free Diet Safer? -- (6) Plant-based Meat: Building Meat from Plants -- (7) Biotech Meat: Growing Meat from Cells -- (8) Bug Meat: Assembling Meat from Insects -- (9) The Past is the Future: Tofu and Tempeh Rejuvenated -- (10) Future Foods: Diet 2050.
    Abstract: Reducing the amount of meat in our diet would have major environmental benefits, including reducing greenhouse gas emissions, pollution, deforestation, and biodiversity loss. Moreover, it would have wide-ranging ethical benefits by decreasing the huge number of livestock animals confined and killed each year for food. For consumers, there may also be health benefits from a meat-less diet, provided it was carefully planned. Advances in modern science and technology, including plant-based, microbial, lab-grown, and insect meats, are revolutionizing the food industry and making it easier for consumers worldwide to maintain a meat-less diet. In Meat Less: The Next Food Revolution I outline my own journey as a food scientist who became a vegetarian in solidarity with my daughter. In writing this book I take the viewpoint that there are no easy answers and that everyone must make the decision to eat meat or not based on their own values. The first chapters examine the impact of meat consumption on the environment, human health, and animal welfare, including the important questions of how much does eating meat really contribute to greenhouse gas emissions, pollution, and biodiversity loss, what are the ethical implications of raising and killing animals for food, and the impact of reducing meat consumption on human nutrition and health. I then discuss some of the new technologies that are being developed to create alternatives to meat, including plant-based meat, cultured (lab-grown) meat, microbial meat, and insect meat. I present the science behind these new technologies and their potential for making a difference to climate change and human health. In the final chapter, I discuss why I remain a vegetarian and have decided to dedicate the rest of my scientific career to finding sustainable and healthy alternatives to meat, presenting my vision of the human diet in 2050.
    Type of Medium: Online Resource
    Pages: XVII, 251 p. 70 illus., 66 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031239618
    Series Statement: Copernicus Books, Sparking Curiosity and Explaining the World,
    DDC: 570
    Language: English
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  • 41
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Pharmacology. ; Pharmaceutics.
    Description / Table of Contents: Preface -- Abbreviations -- Chapter 1 – Why you need this book and why I wrote it -- Chapter 2 – What you need to do before you write a grant -- Chapter 3 – The idea -- Chapter 4 – Go solo or collaborate? -- Chapter 5 – What the entrepreneur needs to know -- Chapter 6 – The grant package -- Chapter 7 – The main event – writing it -- Chapter 8 – Edit / Polish / Shine / Repeat -- Chapter 9 – Are you ready to submit it? -- Chapter 10 - Post submission steps to win the grant -- Afterthoughts -- Index -- About the Author.
    Abstract: As an academic or a small business owner, you will need to write grants at some point in your career. Writing them though is not enough, what you also need to know is how to win grants. Much has been written about writing grants, the mysterious special ability called ‘grantsmanship’, so it occurred to me that there is a need to come at this differently and spill the beans. The difficulty in getting a grant, in particular an NIH grant like an R01 in the USA is often described, it is competitive and gets tougher every year. Your proposal therefore must stand out, it must connect with the reviewers. This is true for all types of grants, give the reviewer what they want always. But also, you need to connect to the program officer, the committee that ultimately makes funding decisions and you must take care of a myriad of other details outside of the main event which is describing the “science”. This means you cannot rely on just out-writing the competition, it is more than that as you have to out-think, out-strategize and out-schmooze them. If you have been continually funded for decades that is terrific, but if you want to keep being funded there is no guarantee what got you there will keep you there. What was a hot technology 4-5 years ago is not the new thing anymore, you will need to do something different, but what? You therefore need to not only think about writing great grants, you need to put it into practice and win them. Having written and won grants from the NIH and DOD over the past 17 years (and longer by the time you read this) I possess a valuable perspective. Each grant and study section will be different. Whether a big or small grant it does not seem to make a difference the reviewers will critique your efforts, they may not like it, they may reject your ideas or they may love it. You have some small degree of control until the proposal leaves your hands or more correctly you click ‘submit’. You will need to differentiate your grant from the hundreds of others in many ways, but you cannot change who you are, your history so how you describe yourself and team will also have an impact. You could spend hundreds of hours on your proposal or just a day and the outcome might still be the same. This small book is a summary of my own personal experiences and will provide some advice that will help you learn how to do a better job of winning grants. This book is written by a scientist who writes the grants and develops commercial products; Provides a unique perspective on what you need to write better grants; Teaches you how to continually win grants; This book provides examples from the authors own grant applications; The reader will be inspired to start a company to win small business grants.
    Type of Medium: Online Resource
    Pages: XIX, 106 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031275166
    Series Statement: AAPS Introductions in the Pharmaceutical Sciences, 17
    DDC: 615
    Language: English
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  • 42
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Agricultural genome mapping. ; Agronomy. ; Plant genetics. ; Agricultural Genetics. ; Agronomy. ; Plant Genetics.
    Description / Table of Contents: Part I. Molecular Genetics -- Chapter 1. Introduction to genetics -- Chapter. 2. DNA as hereditary material -- Chapter. 3. Central Dogma of Molecular Biology -- Chapter. 4. Applications of molecular biology in agriculture -- Part. II. Mendelian Genetics -- Chapter. 5. DNA, Genes, Cells and Mendelian Genetics -- Chapter. 6. Gene interactions -- Chapter. 7. Sex-linked inheritance -- Chapter. 8. Gene linkage -- Chapter. 9. Extranuclear inheritance -- Chapter. 10. Chromosomal mutations -- Part. III. Population Management -- Chapter. 11. Population genetics -- Chapter. 12. Quantitative Genetics -- Chapter. 13. Heterosis -- Chapter. 14. Population management and Genetic Improvement.
    Abstract: Readers will find in this book a comprehensive text on the intersection of genetic and agriculture, addressing the different levels at which DNA is studied for agricultural purposes. The different subdivisions of genetics (molecular, Mendelian, quantitative and populations) are all discussed in the light of agriculture research and practice. Agricultural Genetics aims to be a support for advanced and undergraduate students taking courses on biology, genetics and breeding applied to agriculture, both for plant sciences and animal sciences.
    Type of Medium: Online Resource
    Pages: X, 210 p. 110 illus., 68 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031371929
    DDC: 631.5233
    Language: English
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  • 43
    Keywords: Medicine Research. ; Biology Research. ; Medical education. ; Materials Microscopy. ; Anatomy. ; Cytology. ; Education Data processing. ; Biomedical Research. ; Medical Education. ; Microscopy. ; Anatomy. ; Cell Biology. ; Computers and Education.
    Description / Table of Contents: Part I. Advances in Microscopy for Visualization, Education and Healthcare Practice -- Chapter 1. Visualizing the Invisible: Microscopy and How It Affects Our Understanding of Cells and Tissues -- Chapter 2. Morphometric Image Analysis and Its Applications in Biomedicine Using Different Microscopy Modes -- Chapter 3. The Shift in Power from Conventional to Digital and Virtual Microscopy -- Chapter 4. How Visualizations Have Revolutionized Taxonomy: From Macroscopic, to Microscopic, to Genetic -- Chapter 5. Bright New World: Principles of Fluorescence and Applications in Spectroscopy and Microscopy -- Chapter 6. An Introduction to Particle Tracking Techniques with Applications in Biomedical Research -- Chapter 7. An Exploration of the Practice of CT Modalities to Evaluate Anterior Cranial Deformities in Craniosynostosis -- Part II. Anatomical and Cell Biology Education -- Chapter 8. The Use of Biomedical Imaging in Visuospatial Teaching of Anatomy -- Chapter 9. Ultrasound Imaging for Musculoskeletal Research -- Chapter 10. Skill Acquisition in Histology Education.
    Abstract: This edited book has a strong focus on advances in microscopy that straddles research, medical education and clinical practice. These advances include the shift in power from conventional to digital microscopy. The first section of this book covers imaging techniques and morphometric image analysis with its applications in biomedicine using different microscopy modes. Chapters highlight the rich development of fluorescence methods and technologies; particle tracking techniques with applications in biomedical research and nanomedicine; the way in which visualizations have revolutionized taxonomy from gross anatomy to genetics; and the psychology of perception and how it affects our understanding of cells and tissues. The book’s first section concludes by exploring the use of CT modalities to evaluate anterior deformities in craniosynostosis. In the second section of the book, chapters on anatomical and cell biology education explore the history of anatomical models and their use in educational settings. This includes examples in 3D printing and functional human anatomical models that can be created using easily available resources and the use of biomedical imaging in visuospatial teaching of anatomy; the novel use of ultrasound in medical education and practice; and skill acquisition in histology education using a flowchart called a ‘decision tree’. This book will appeal to histologists, microscopists, cell biologists, clinicians and those involved in anatomical education and biomedical visualization, as well as students in those respective fields.
    Type of Medium: Online Resource
    Pages: XIV, 228 p. 107 illus., 94 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031368509
    Series Statement: Biomedical Visualization, 2
    DDC: 610.72
    Language: English
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  • 44
    Keywords: Cytology. ; Stem cells. ; Cancer. ; Biophysics. ; Pharmacology. ; Regenerative medicine. ; Cell Biology. ; Stem Cell Biology. ; Cancer Biology. ; Biophysics. ; Pharmacology. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: Direct Cardiac Reprogramming: Current Status and Future Prospects -- Stem Cell-Based Therapeutic Approaches in Genetic Diseases -- Gene Therapeutic Delivery to the Salivary Glands -- Cancer Stem Cells and Their Therapeutic Usage -- Rafting on the Plasma Membrane: Lipid Rafts in Signaling and Disease -- Sounding a New Era in Biomechanics with Acoustic Force Spectroscopy -- Drug Therapeutics Delivery to the Salivary Glands: Intraglandular and Intraductal Injections -- Negative-Pressure Wound Therapy: What We Know and What We Need to Know -- Vitamin A Deficiency, COVID-19, and Rhino-Orbital Mycormycosis (Black Fungus): An Analytical Perspective -- Treatment Strategies for Multiple Myeloma Treatment and the Role of High-Throughput Screening for Precision Cancer Therapy. .
    Abstract: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of Springer Nature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the 20th volume of a continuing series.
    Type of Medium: Online Resource
    Pages: VIII, 189 p. 18 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031416880
    Series Statement: Cell Biology and Translational Medicine, 1436
    DDC: 571.6
    Language: English
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  • 45
    Keywords: Biology. ; Human ecology Study and teaching. ; Biological Sciences. ; Environmental Studies.
    Description / Table of Contents: Chapter 1: An Introduction to Small Island Developing States and Building Resilience to Climate Change in the Caribbean -- Chapter 2: Principles of Systemic Resilience to Climate Change in Small Island Developing States -- Chapter 3: Nature-based Solutions for Building Resilience in Small Island Developing States in the Caribbean -- Chapter 4: Assessment of the Effectiveness of Nature-based Solutions for Land Restoration in St. Kitts and Nevis -- Chapter 5: Building Resilience for Caribbean Nations: Showstoppers and Opportunities from Economics and Governance.
    Abstract: This book summarizes approaches that integrate the environmental, economic, and physical domains with the values, and needs of the population are necessary to develop sustainable strategies that will enhance the resilience of small islands, within the context of inter-island differences in geology, ecology, societal attitudes, governance, and human and economic resources. The impacts of coastal damage and flooding are predicted to worsen during this century due to rising sea levels and increases in the frequency and intensity of storms. The usual approach to coastal protection in Small Island Developing States (SIDS) in the Caribbean is to view both the hazards and the solutions from the “Ocean Side” perspective and to react with “hard” engineering solutions. These structural engineering approaches prevent damage and disruptions to services associated with predictable events but leave communities vulnerable to future events that do not follow historical trends. Furthermore, engineered structures do not adequately address the systemic nature of climate change nor account for compounding threats (e.g., coincidence of hurricane season and global pandemics). To move from this traditional strategy for managing risks from coastal hazards, we need to consider a portfolio of solutions that enhance island protection and community resilience. Nature-Based Solutions (NBS) are gaining attention as practical and cost-effective approaches for mitigating climate-based stressors. However, deployment of NBS strategies requires spatial coordination within the context of “ridge to reef” or integrated water resource management (IWRM) approaches that include the creation of conditions for social acceptance, equity, effective governance, and financial incentives.
    Type of Medium: Online Resource
    Pages: XIV, 95 p. 28 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031373763
    Series Statement: Environmental Contamination Remediation and Management,
    DDC: 570
    Language: English
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  • 46
    Keywords: Medical care. ; Medicine Research. ; Biology Research. ; Artificial intelligence. ; Biotechnology. ; Public health. ; Health Care. ; Biomedical Research. ; Artificial Intelligence. ; Biotechnology. ; Public Health.
    Description / Table of Contents: Society 5.0: Realizing Next Generation Healthcare -- Health informatics applications in healthcare and society 5.0 -- Society 5.0 and quality multidisciplinary care for malignant solid tumors in low- and middle-income settings -- Technological Innovations and the Advancement of Preventive Healthcare for Society 5.0 -- Internet of Things in Society 5.0 and the Democratization of Healthcare -- Merging CyberSpace with Physical Space to Improve Cervical Cancer Management and Women’s Health in Low-Middle-Income Countries -- AI Enhanced Drug discovery and the achievement of next generation human-centered health system -- The role of digital twinning, the next generation of EMR/EHR, in healthcare in a society 5.0: collecting patient data from birth to the grave -- Integration of Cyber-Physical Systems in the Advancement of Society 5.0 Healthcare Management -- Transformation of the healthcare ecosystem in the era of Society 5.0 -- Healthcare transformation using Blockchain technology in the Era of Society 5.0 -- Society 5.0 Healthcare: Ethics, Legal Rights, Human Rights, Safety and Security -- Way forward for Society 5.0 and Next Generation Healthcare.
    Abstract: This book analyses the ability of technological advancements to represent, enhance, and empower multidisciplinarity in the context of Society 5.0. and next generation medicine. New technologies allow patients to communicate with medical personnel anytime, anywhere and shape the terrain of healthcare ecosystem at an unprecedented rate. Five main trends become apparent in this process: Hybrid care models combining virtual and in-person services, digitization of healthcare specialties, increased Artificial intelligence (AI) adoption, health systems moving to the cloud and advanced precision medicine. In its chapters the book dissects the important roles for technologies in areas such as digital twinning, big data, Internet of Things, AI, cyber-physical systems, blockchain technology to lead the healthcare digitalization envisioned in Society 5.0. Throughout the book the authors discuss how to incorporate these new technologies legally, ethically, safely, and securely and in keeping with the highest standards of human rights. It also advocates for the need for careful oversight and mindful allocation of resources and energy for sustainable development. This book, written by experts in the field from academia and industry, will appeal to researchers, healthcare professionals, policy makers, teachers and students interested in the ways healthcare is reorganized based on digital transformation efforts and the rethinking of care, including technologies.
    Type of Medium: Online Resource
    Pages: VI, 298 p. 57 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031364617
    DDC: 610.73
    Language: English
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  • 47
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Botany. ; Environmental management. ; Environmental geography. ; Social sciences. ; Sustainability. ; Plant Science. ; Environmental Management. ; Integrated Geography. ; Society. ; Sustainability.
    Description / Table of Contents: Introduction -- Review of Literature -- Data Base and Methodology -- India’s Forest Cover, Forest policies and Acts and Impact of Governance on Forest Cover -- Institutions & Enforcement at Local Level -- Forest Dependency and Forest Governance in South Bengal and North Bengal Forest Divisions -- Conclusions and Policy Recommendations.
    Abstract: This book addresses quantitative assessment of forest governance and how local-level institutions work in governing efficient ways of forest resource management so that sustainable development of forest is ensured. The research is done at the micro-level as well as macro-level in India. The research presented here focuses on forest governance and institutions in the two forest divisions of West Bengal say South Bengal and North Bengal. The research covers 36 villages, 844 households, 10 Gram panchayat, 12 Beat offices, and 36 Forest protection Committees in West Bengal and also studies different local-level institutions like local communities/households; Joint Forest Management Committees (JFMC)/Forest Protection Committees (FPCs); Community Forest Management groups; Van Panchayats; Village Councils (schedule VI area) and Biodiversity Management Committees; Eco-development committees, NGOs and Self-Help Groups, and Panchayati Raj Institutions (PRIs). Chapters also address various issues like monitoring, enforcement, rule of law, transparency, accountability, participation, control of corruption, government effectiveness, regulatory quality, and sustainable livelihood in connection with the study of forest governance. This research is associated with different sectors like agricultural sector, forestry sector, informal sectors and rural development, etc., and involved multi-stakeholders. Particular attention is given on the policy-oriented research which is the cornerstone of SDG of 16. Developmental practitioners, government implementation agencies, researchers in environmental science and social science, and policymakers find this book appealing. .
    Type of Medium: Online Resource
    Pages: XIV, 231 p. 48 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031347467
    DDC: 580
    Language: English
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  • 48
    Keywords: Botany. ; Agriculture Economic aspects. ; Alternative medicine. ; Pharmacology. ; Agronomy. ; Agriculture. ; Plant Science. ; Agricultural Economics. ; Complementary and Alternative Medicine. ; Pharmacology. ; Agronomy. ; Agriculture.
    Description / Table of Contents: 1. Khikeya Semy*, Ruokuonuo Kuotsu -- Ethnobotanical study of medicinal herbs used by the Naga tribals of Eastern Himalayas -- khikeyasemy@gmail.com -- 2. Ahirrao YA1, Patil MV2 and DA Patil3* -- Ethnomedicinal Use-reports of Seeds As Tapped From Herbal Vendors In North Maharashtra (India) -- dapatil_10aug@yahoo.com -- 3. Pious Soris Tresina, Murugeswaran Santhiya Selvam, Vallinayagam Sornalakshmi and Veerababu Ramasamy Mohan -- Ethnobotanical Study of Medicinal Plants Used by Traditional Healers in Grizzled Squirrel Wildlife Sanctuary -- vrmohanvoc@gmail.com -- 4. Jayalekshmi C V 1† , Reshma K Ramesh 1† , Vijai M 2† & Suresh V* -- Ethnomedicinal Plants used by Irula Tribal Settlement of Attappady in Palakkad District Kerala, India -- 5. Jayalekshmi C V 1† , Reshma S 2† & Suresh V* -- Folk Medicine Of Chittur Taluk In Palakkad District, -- 6. R. Manikandan 1 , S.P. Nithya, R. Mehala Devi -- Checklist Flora of Sunderdhunga Valley, Western Himalaya, with Emphasis on Ethno-Medicinal Plants -- 7. Pinki Gogoi, Pyonim Lungphi, A.P. Das & Ayam Victor Singh * -- Phytomedicines Used In Respiratory Diseases By Traditional Healers Of Lakhimpur & Dhemaji Districts Of Assam, India -- 8. Lydia Yeptho*, T. Ajungla -- Understanding phytomedicinal gastronomic culture of the Nagas in Nagaland, India -- 9. Ritee Basu, Sukanya Dasgupta, Spoorthy N Babu, Ayesha Noor* -- Medicinal Plants in the Indian Traditional Medicine and Current Practices -- 10. Rajeev Ranjan Kumar, Jaidev Chauhan, Vijay Kant Purohit and Pratti Prasad -- Conservation of RET Medicinal and Aromatic plants, for their Appraisal in Traditional Medicines and Current practices in Indian Himalayan Region -- 11. Neva Chaudhary 1* , Suresh K. Ghimire 2 and Ram P. Chaudhary -- Traditional Amchi Medicinal Practice in trans-Himalayas of Nepal: Conservation and Bioprospecting -- 12. Salman Majeed 1* , Muhammad Zafar 1 , Mushtaq Ahmad 1,2 , Shazia Sultana 1 , Muhammad Fethi, Ozdemir 3 , Omer Kilic 4 , Ghulam Yaseen 5 , Nabila 1 -- Appraisal of Medicinal Plants Diversity Inhabited in Deserts Areas -- 13. Karma Yeshi, Phurpa Wangchuk -- Bush Medicinal Plants of the Australian Wet Tropics and Their Biodiscovery Potential -- 14. Kausar Rashid1*, Sufiya Rashid1, Aijaz Hassan Ganie2, Irshad A. Nawchoo1, Mudasir A. Tantry3, Anzar A. Khuroo4 -- Trillium govanianum, a promising endemic medicinal herb of the Himalaya -- 15. K. Abirami, P. Revathi, K. Thenmozhi* and K. Sowndhararajan -- Comprehensive Review on Wild Basil Genus Orthosiphon of Lamiaceae -- 16. T. Soumya, P. R. Jayasree and P. R. Manish Kumar -- Zingiberaceae plants – a cornucopia of promising chemotherapeuticals for cancer cure -- 17. Nikita Patel and Ramar Krishnamurthy -- Moringa oleifera Accessions: Perspectives and application as nutraceuticals and phytomedicines -- 18. Sreeja Puthanpura Sasidharanc, Xuefei Yanga,b, Karuppusamy Arunachalama,b* -- An overview of ethnobotany, phytochemicals and pharmacological properties of Ficus species -- 19. Sunil Kumar 1 , Bikarma Singh 2,3 -- Phytochemistry and pharmacology of Catharanthus roseus (L.) G. Don and Rauvolfia serpentina (L.) Benth. ex Kurz -- 20. Naveen Dhingra* 1 , Shaligram Sharma 2 , Pratima Kumari 3 and Anand Kar 4 -- Resilience Activity of Glycyrrhiza glabra in Relation to Cancer: Chemistry and Mechanism -- 21. Reshmi Chembrammal 1 *, Aswathi Pokkadath 2 and John Ernest Thoppil 3 -- Strobilanthes: A plethora of phytomedicine -- 22. Sonia Mol Joseph* And Amala Dev A.R -- Annonaceae: Tropical medicinal plants with potential anticancer compounds: An overview -- 23. Suman Thamburaj † , Chayanika Sarma † , Anju Mariam Johnson † , Akhila Etikala † and Suresh Kumar Kalakandan* -- Biocolorant from Anisochilus carnosus: A natural food preservative -- 24. Azhagu Saravana Babu. P 1 , Vajiha Aafrin. B 2 , Sagorika Goyali 1 , Geethika. M 1 , Sugumari.V 1 , M. Sukumar -- Therapeutic properties of Nardostachys jatamansi and its applications in Post Chemotherapy induced hair loss in cancer patients -- 25. Marney Pascoli Cereda -- Phototherapeutic potential of cassava (Manihot esculenta, Crantz). -- 26. Saranya Surendran and *Raju Ramasubbu -- Phytochemistry and Pharmacological studies of Indian Cinnamomum Schaeff. -- 27. Silvy Mathew, Reshma Rajan -- Medicinal properties and population studies on Sarcostigma kleinii Wight &Arn. -- 28. Anjana Krishnan1, Jomy Joseph2 and Sudha Kalyanikutty1*, -- The Utility of Natural Mucilage from the Medicinal plant, ‘Patha’ (Cyclea peltata) as an Alternative for Solidifying Agent in Cell Growth Media -- 29. S. N. Preethamol 1 * and John E Thoppil 2 -- Secondary metabolites in Ophiorrhiza brunonis Wight &Arn. (Rubiaceae): A lead towards its anticancer potential -- 30. Kajal Chakraborty -- Marine macroalgae as a treasure house of bioactive compounds and nutraceuticals -- 31. Kapish Kapoor †1* , Priyal Jain †2 Joohee Pradhan †1* -- Plant metabolites as new leads to herbal drug discovery: Approaches and Challenges -- 32. Mudasir Maqbool 1 , Kitika Shenmar 2 , Ansab Akther 3 , Reyaz Hassan Mir 2 , Adil Farooq Wali 4* , Roohi Mohi-ud-din 5* -- Biochanin A Chemistry, Structural Modifications, and Therapeutic Applications: An Update -- 33. Biswajit Patra 1 , Nibedita Das 2 , Mohammad Zaki Shamim 3 , Tapan Kumar Mohanta 4, Bishwambhar Mishra 4 , Yugal Kishore Mohanta 5* -- Dietary Natural Polyphenols Against Bacterial and Fungal Infections: An Emerging Gravity in Health care and Food industry -- 34. Joohee Pradhan 1 * Purnima Paliwal 2† Sunita Panchawat 1† Rohini Trivedi 3† , and Devshree Gayakwad 4† -- Phyto-constituents as Potential Leads for the Development of Novel Antiepileptic Drugs -- 35. Hitesh Chopra 1 , Shabana Bibi 2 , Yugal Kishore Mohanta 3 , Sony Kumari 3 , Atif Amin Baig 4* -- Role of Polyphenols in Cardiovascular diseases -- 36. Alankar Shrivastava -- Steam Distillation: Principle And Applications For The Extraction Of Essential Oils From Plants -- 37. Durga Prasad Barik -- Factors Influencing Agrobacterium-Mediated Transformation Efficiency In Plants – A Case Study -- 38. Dr T V Binu, C B Athira -- Evaluation Of Medicinal Planttager With Reference To Its Substitute -- 39. Shipra Jha1, Shilpi Yadev2 -- Biotechnology: Production of Natural Bioactive Compounds from Leguminous Plants & Disease Management -- 40. Pawan Mulani*, Dr.Sweta S.Koka, Anirudh Padiyar, Dr. R.K. Maheshwari, Dr. G.N. Darwhekar -- Novel Ecofriendly Method Of Extraction For Fixed Oils Using Solvent Action Of Solid Solubilizers -- 41. 1Yasotha Jeyaram, 2Priya Prasannan, 1Arjun Pandian, 2*Ramasubbu Raju -- Conservation attempts of woody medicinal plants of India by Biotechnological tools -- 42. M.V Lakshmi, S. Jeyaraj, and T.S Swapna -- Conservation of endangered medicinal plants by in-vitro propagation methods -- 43. Nadia Iqbal 1* , Sidra Nisar Ahmed 2 , Urooj subhan 1 , Nageen Arif 1 , Humaira Saleem 1 , Farah Deeba 1 -- Application of biotechnology to produce plant-derived biologically important compounds -- 44. Mehmet Zeki Kocak 1 * , Mustafa Güven Kaysim 2 -- Appraisal of Medicinal Plants for Pharmacological Properties -- 45. Yuhong Zheng 1 , Xin Shi 2 , Li Fu 3* -- Pharmacological properties and tissue culture method of endangered medicinal plants -- 46. Morvarid Noormohammadi 1 , Farzad Shidfar 2* -- Natural compounds with pharmacological properties in clinical trials -- 47. Aswathi Pokkadath1, Reshmi Chembrammal2, and John Ernest Thoppil3 -- Phytopharmacological aspects of the genus Terminalia -- 48. Priyanka Soni 1 , Md. Sajid Ghufran 2 and Govinda Rao Duddukuri 3 * -- Anticancer potential of plant-derived compounds: An overview of their epigenetic mode of action -- 49. Nikita Kale -- Treatment of Cancer Using Combination of Herbal & Novel Drug Delivery System -- 50. Nisha Sam Nirmala* 1 , Navina Bala Krishnan 1 , Vaishnavi Vivekanandan 1 , Krishnaraj Thirugnanasambantham -- Anti-Inflammatory Potential Of Lead Compounds And Their Derivatives From Medicinal Plants -- 51. Tanima Bhattacharya a,b# , Debashrita Das c# , Hitesh Chopra d , Atif Amin Baig* e -- Alzheimer disease treatment using natural foods: A perspective overview -- 52. Anjali Saharan 1 , Harkiran Nehra 2 , Chander Parkash 3 , Rakesh Kumar Sindhu 4 , Inderjeet Verma 3 -- Natural products used for the treatment of an autoimmune disorder -- 53. Cristina M. Pérez Zamora 1,2*† , Carola A. Torres 1,2*† and Ana M. Gonzalez 3 -- Strategies to improve antimicrobial activity of natural products: approaches and challenges -- 54. Sinimol Thekkekkoottumughath Peethambaran1* -- Plants Described In Ayurveda With Immunomodulatory Potential -- 55. B Sumithra 1*, Sanjeeb Kumar Mandal 1, B Bishwambhar Mishra 1, Mounika KVSSN 1, Caleb Joel Raj J 1, Aishwarya CVS 1. -- Plant-derived drugs for Alzheimer’s and other neurological disorders -- 56. Afroze Naveed Basha 1 , Ramya Subramanian 2 , Kandeepan Chithan 1 , Gopinath Gurulingam, Vincent 3 , Karthigeyan Murugesan 3 , Ananthavalli Ramachandran 3 , Sivakumar Pethanan 3 , Mani, Panagal 4 , Chella Perumal Palanisamy 5* , Jayakumararaj Ramaraj 6* -- Properties and mechanism of antimicrobial agents from plant derived essential oils -- 57. Thomson Alex 1 , Alankar Shrivastava 2* , Damanpreet Kaur Lang 3 , Rakhi Khabiya 4, Sweta S. Koka 4 , Yasmin Sultana 1* -- Nanotechnological Modus Operandi For The Delivery Of Cytotoxic Phytochemicals -- 58. a Arun John and b Rinu Elizabeth Roy -- Plant Based Green Nano Particles In Cancer Diagnosis And Chemotherapy -- 59. Jeyanthi Palanivelu, R. Sai Nandhini, Kalpana Shree S, Phalguni Maity, G.S.Madhumathi, Anindita Bhar , Jeyanthi Palanivelu* -- Use Of Nanoparticles In Cancer Therapy Using Plant Resources -- 60. Md. Sajid Ghufran 1* , Priyanka Soni 2 and Govinda Rao Duddukuri 3 -- The global concern for cancer emergence and its prevention: A systematic unveiling of the present scenario -- 61. Shaikh Ajij Ahmed Makbul 1,* Sayeedur Rahman 2 -- Regularly used poisonous medicinal pl.
    Abstract: This book focuses on natural products, in particular medicinal plants and their derived products, as an indispensable source of bioactive molecules that serve as either drug candidates or lead compounds for drug design and discovery . There are several advantages for plant-derived therapeutics, including wide availability, diverse pharmacological actions, and a generally good profile of safety and tolerability. Over the recent years, there have been numerous reports from clinical studies testifying the efficacy and safety of medicinal plants and phytochemicals in treating human diseases. A plethora of basic studies has also unraveled molecular mechanisms underlying the health benefits of herbal medicines. Nevertheless, issues such as identification of bioactive ingredients, standardization of the products, and drug interactions remain to be systematically documented. Bioprospecting of Tropical Medicinal Plants represents a comprehensive analysis of natural products, mainly medicinal plants and phytochemicals. It includes detailed medicinal properties and pharmacological action from in vitro models to clinical trials. The goal is to present the readers a carefully curated collection of plant-derived natural products and their underlying molecular mechanisms.
    Type of Medium: Online Resource
    Pages: XVII, 1544 p. 150 illus., 132 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031287800
    DDC: 580
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Philosophy of mind. ; Neurosciences. ; Psychiatry. ; Cognitive psychology. ; Philosophy of Mind. ; Neuroscience. ; Psychiatry. ; Cognitive Psychology.
    Description / Table of Contents: Introduction -- The Subjective Experience: a brief review -- Two mentalistic portraits: the book and its content -- Workings of the mind: consciousness and the unconscious -- The unfolding of Life: the genetic endowment -- The evolutionary archetypes: values and needs -- One of the line: values and needs -- Affective connectedness: the qualia web -- Talking to the stars: the quanta web -- Putting it all together -- Some closing reflections -- References.
    Abstract: This book presents a systematic exploration of the subjective experience, keeping the investigation for the most part within a subjective first person perspective through the use of “vignettes” as sources of data. It also uses incorporates a ‘"third person” objective approach when that is relevant. The goal of Journeys in the Mind is to capture and convey the operations of the mind: both the shared blueprints common to the elaboration of subjective knowledge as well as the immense fishnet of personalized variables that operate in each mental phase-space and act upon the blueprints to continuously recategorize them into sets of coherent, dynamic outcomes, or mental landscapes. Dr. Sanguineti's meditative perspective holds the promise to enrich the way we understand the workings of the human mind. .
    Type of Medium: Online Resource
    Pages: XIII, 121 p. 4 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031297359
    DDC: 128.2
    Language: English
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  • 50
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Agriculture. ; Soil science. ; Sedimentology. ; Conservation biology. ; Ecology . ; Environmental management. ; Agriculture. ; Soil Science. ; Sedimentology. ; Conservation Biology. ; Environmental Management.
    Description / Table of Contents: Chapter 1: Soil And Water Management -- Chapter 2: Water Erosion -- Chapter 3: Modeling Water Erosion -- Chapter 4: Wind Erosion -- Chapter 5: Wind Erosion Modeling -- Chapter 6: Tillage Erosion -- Chapter 7: Tillage Systems -- Chapter 8: Cropping Systems -- Chapter 9: Crop Residue Management -- Chapter 10: Cover Crops -- Chapter 11: Perennial Plants And Soil Management -- Chapter 12: Soil Amendments -- Chapter 13: Mechanical Structures And Engineering Techniques -- Chapter 14: Restoration And Management Of Degraded Soils -- Chapter 15: Soil Fertility Management -- Chapter 16: Nutrient Erosion And Hypoxia Of Aquatic Ecosystems -- Chapter 17: Soil Water Management -- Chapter 18: Management Of Grazing Lands -- Chapter 19: Soil Management And Carbon Dynamics -- Chapter 20: One Health -- Chapter 21: Soil Resilience -- Chapter 22: Food, Water, And Climate -- Chapter 23: The Way Forward.
    Abstract: This updated and expanded second edition textbook, describes all main aspects of soil management, to address the serious problems of soil erosion and the attendant environmental pollution. The global high demands for food, fiber, feed, and fuel put a constant strain on the environment, which can only be mitigated by soil conservation. This edition incorporates new concepts and provides an up-to-date review of soil management principles and practices. The authors also added new chapters on cover crops, crop residues, soil water management, nutrient management, perennials in crop rotations and organic amendments. All practices have a clear perspective on addressing soil erosion, physical and chemical problems, carbon dynamics and sequestration as well as non-point source pollution. The restorative nature of many practices, also consider water conservation as a main pillar of sustaining a healthy soil. This textbook is valuable for students and professionals in soil science, agronomy, agricultural engineering, hydrology, and management of natural resources.
    Type of Medium: Online Resource
    Pages: XXII, 611 p. 181 illus., 95 illus. in color. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9783031303418
    DDC: 630
    Language: English
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  • 51
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Medicine Research. ; Biology Research. ; Medical education. ; Anatomy. ; Education Data processing. ; Biomedical Research. ; Medical Education. ; Anatomy. ; Computers and Education.
    Description / Table of Contents: Part I. History of Medical Illustration, Graphic Medicine, Humanizing Healthcare and Equitable Visualizations -- Chapter 1. Drawn Together: Merging the Worlds of Health and Comics Through Graphic Medicine -- Chapter 2. Medical Graphics and Graphic Medicine -- Chapter 3. Decolonising Visual Narratives in Global Health: The Case for Equitable and Ethical Imagery Use -- Chapter 4. Medical Illustration in Anatomy -- Chapter 5. Valuing Creativity in Biomedical Science Education: A Reflective Narrative -- Chapter 6. Biomedical Visualization in Embryology Education: A Scoping Review -- Chapter 7. A Framework for the Design, Production, and Evaluation of Scientific Visualizations -- Part II. Anatomical and Cell Biology Education -- Chapter 8. Palpation: The Art of Felt Anatomy -- Chapter 9. Teaching Histology with Analogies -- Chapter 10. Using the Hands for Learning Anatomy -- Chapter 11. Corporeal Pedagogy: Visualizing Anatomy Through Art, Archaeology and Medicine.
    Abstract: This book contains subjects by authors with a fresh, exciting and extensive focus within the medical humanities, offering the reader chapters which include the history of medical illustration, Graphic Medicine as a vehicle for the expression of humanistic dimensions of healthcare, equitable and ethical medical illustrations, as well as novel, art-based approaches in anatomical education. Authors consider the role of visual narratives in medical and scientific illustration, the unique affordances of the comics medium, the history of comics as a form of medical and scientific visualization, and the role of comics as didactic tools and as vehicles for the expression of the humanistic dimensions of healthcare. A chapter considers ethical and equitable implications in global healthcare practice, and highlights the work currently being undertaken to address inappropriate and problematic depictions of people in global health visualizations. This will inform the reader of emerging and current thinking about visual communication and the use of images in the public domain, as well as in the healthcare and education sectors. Novel approaches in anatomical education include the benefits of three-dimensional anatomy models made of felt, visual analogies as a method to enhance students’ learning of histology, the use of the hands for learning anatomy, and visualizing anatomy through art, archaeology and medicine. This book will appeal to readers who have an interest in the medical humanities, Graphic Medicine, and ethical medical and anatomical illustrations. These include academic and non-academic readers, medical students, medical educators, clinicians, health-care workers, as well as policy makers.
    Type of Medium: Online Resource
    Pages: XIV, 249 p. 88 illus., 81 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031390357
    Series Statement: Biomedical Visualization, 3
    DDC: 610.72
    Language: English
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  • 52
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Agriculture. ; Sustainability. ; Biotic communities. ; Landscape ecology. ; Ecology . ; Agriculture. ; Sustainability. ; Ecosystems. ; Landscape Ecology. ; Ecology.
    Description / Table of Contents: Part I: System definitions -- Chapter 1: Introduction: why agroecology, why systems, why now? -- Chapter 2: Systems approach: analysis, design and modelling -- Chapter 3: Structure, functions and diversity of agroecosystems -- Part II: Analysis-oriented approaches -- Chapter 4: Categorising diversity through rural household typologies -- Chapter 5: Production functions and factors in agroecosystems -- Chapter 6: Landscape structure, functions and biodiversity -- Chapter 7: Spatial heterogeneity in agroecosystems -- Part III: Design-oriented approaches -- Chapter 8: Evaluation and indicators in the design of agroecosystems -- Chapter 9: Trade-offs around production and livelihood decisions -- Chapter 10: Pathways for agroecological transitions.
    Abstract: As agroecology gains momentum in the international research-for-development arena, there is an urgent need for methods and tools to support the co-design and evaluation of agroecological systems and their transitions. The social and ecological complexity of agroecosystems, their dynamics, uncertainties and sustainability, calls for an holistic, systemic approach to agroecology, which leads to questions such as: how do we deal with heterogeneity, landscapes, biodiversity or learning processes in agroecosystems analysis? How do we categorize diversity or analyse trade-offs in social-ecological interactions? How do we conceptualize, co-design and monitor agroecological transitions? This book sets out to answer these questions by building on the valuable ‘classics’ in agroecology. The book presents a systems perspective that underpins a combination of methodologies, ranging from participatory tools and field observations to mathematical simulation modelling. Researchers, advanced students and transdisciplinary practitioners will find in this book insights and methods to design research and (co-) innovation processes to foster agroecological transitions.
    Type of Medium: Online Resource
    Pages: XX, 393 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031429392
    DDC: 630
    Language: English
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  • 53
    Keywords: Biomolecules. ; Physical biochemistry. ; Macromolecules. ; Molecular biology. ; Biophysics. ; Proteins . ; Bioinformatics. ; Structural Biology. ; Molecular Biology. ; Molecular Biophysics. ; Protein Biochemistry. ; Biophysics. ; Bioinformatics.
    Description / Table of Contents: 1 Papain-Like cysteine protease (PLpro) -- 2 3C-Like protease (3CLpro) -- 3 RNA-dependent RNA polymerase (RdRp) -- 4 RNA-helicase -- 5 RNA-helicase binding with [RdRp, NSP7, NSP8a, NSP8b, pRNA, tRNA, ADP-Mg2+, ATP-Mg2+] -- 6 RNA-helicase binding with [ADP-Mg2+, ATP-Mg2+, and RNA] -- 7 Spike (S) glycoprotein -- 8 Spike (S) glycoprotein D614G mutant -- 9 Spike (S) glycoprotein N501Y mutant -- 10 Spike (S) glycoprotein N165A-and-N234A mutant -- 11 SARS (SARS-CoV-1) -- 12 MERS-coronavirus (MERS) -- 13 Human-ACE2, human-L6, human-L6R, human-nAChRs -- 14 PLpro binding with 12 compounds -- 15 3CLpro binding with N3/Lopinavir/Ritonavir -- 16 3CLpro dimer binding with 7 HIV-inhibitors and Others -- 17 Spike RBDs binding with 50 drugs -- 18 Human ACE2 ectodomain binding with 78 drugs -- 19 Spike-and-ACE2 binding with 100 drugs -- 20 Envelope protein (E-protein) -- 21 Membrane glycoprotein (M-protein) -- 22 Nucleocapsid phosphoprotein (N-protein) -- 23 SARS-CoV-2 RNA genome -- 24 NSP7, NSP8, NSP9, NSP10, NSP16, NSP14 -- 25 NSP15 -- 26 Other mutants -- 27 Vaccines and Drugs -- 28 Pandemic Mathematical Models, Epidemiology and Virus Origins -- A Mathematical Optimization Algorithms and Free Energy Calculations -- References -- Index.
    Abstract: COVID-19 has brought us extensive research databases in the fields of biophysics, biology, and bioinformatics. To extract valuable structural bioinformatic information of SARS-CoV-2 structural and nonstructural proteins, it is necessary to work with large-scale datasets of molecular dynamics (MD) trajectories that need to be optimized. This monograph serves as a comprehensive guide to optimization-based MD studies of the molecular structures of SARS-CoV-2 proteins and RNA. The book begins by performing local optimization, taking into account the three-body movement and optimizing the noncovalent bonds of each molecular structure. The optimized structures reach a transition state that offers the best stability and lowest energy. The optimization process utilizes a hybrid strategy that combines mathematical optimization with various local search algorithms. This approach significantly reduces data volume while eliminating irrelevant bioinformatics data. To gain a thorough understanding of molecular stability and the mechanism of action, it is essential to consider not only static NMR, X-ray, or cryo-EM structures but also dynamic information obtained through MD or Quantum Mechanics/Molecular Mechanics (QM/MM) simulations. These simulations capture the internal motions and dynamic processes of molecules. Furthermore, for each protein, the structural bioinformatics obtained from the optimized structure is validated by analyzing large-scale MD trajectory databases, which are openly and freely available online. The analysis includes key structural bioinformatics aspects such as salt bridge electrostatic interactions, hydrogen bonds, van der Waals interactions, and hydrophobic interactions specific to each SARS-CoV-2 molecular structure. The book also delves into discussions on drugs, vaccines, and the origins of the virus. Additionally, pandemic mathematical models, including those incorporating time delays, are explored. This book is particularly valuable for professionals working in practical computing roles within computational biochemistry, computational biophysics, optimization and molecular dynamics, structural bioinformatics, biological mathematics, and related fields. It serves as an accessible introduction to these disciplines and is also an excellent teaching resource for students.
    Type of Medium: Online Resource
    Pages: XX, 953 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031367731
    Series Statement: Springer Series in Biophysics, 23
    DDC: 572.8
    Language: English
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