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  • E-Books: Biomedical and Life Sciences (AWI only)  (58)
  • Singapore :Springer Nature Singapore :  (58)
  • De Gruyter
  • MDPI - Multidisciplinary Digital Publishing Institute
  • RAND Corporation
  • 615  (45)
  • 636.089  (13)
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  • Books  (58)
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  • E-Books: Biomedical and Life Sciences (AWI only)  (58)
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  • 1
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Cardiology. ; Therapeutics. ; Heart Surgery. ; Pharmacology. ; Cardiology. ; Therapeutics. ; Cardiac Surgery.
    Description / Table of Contents: Coronary Artery Disease: From Mechanism to Clinical Practice -- Evidence in guidelines for treatment of coronary artery disease -- Revascularization For Coronary Artery Disease: Principle And Challenges -- Antithrombotic drugs: pharmacology and perspectives -- Lipid modifying drugs: pharmacology and perspectives -- Anti-hypertensive drugs: pharmacology and perspectives -- Pharmaceutical treatment for Heart failure -- Drug discovery for coronary artery disease.
    Abstract: This book provides an overview of the etiology of coronary artery disease and focuses on the main therapies and drug interventions currently available. It highlights drug pharmacology and therapeutic challenges, with a special emphasis on the underlying principles of available therapeutics and the on-going development of drugs for coronary artery disease. The book is divided into eight chapters, the first of which describes the classical mechanism of coronary artery disease and its clinical presentations. Chapter 2 lists the principles of and related evidence on the prevention and treatment of coronary artery disease. This includes diet and lifestyle management, and guidelines for the treatment of acute coronary syndrome and stable coronary artery disease. In turn, Chapter 3 describes revascularization treatments, covering percutaneous coronary interventions, coronary artery bypass grafts and thrombolysis. This chapter also addresses the main therapeutic challenges. The following chapters provide an overview of three major categories of coronary artery disease drugs, which target thrombosis (Chapter 4), lipid metabolism (Chapter 5), and hypertension (Chapter 6). Heart failure constitutes the major health burden in the late stage of coronary artery disease; accordingly, current heart failure therapeutics and related drug pharmacology are described in Chapter 7. In closing, Chapter 8 provides a summary of on-going clinical trials for coronary artery disease drug development and discusses a number of promising areas in which intensive research into new therapeutics is being pursued. Given its scope, the book will be of interest to clinicians, medical students and research scientists, as well as to pharmaceutical professionals who are seeking new therapies and drugs for coronary artery disease and related disorders.
    Type of Medium: Online Resource
    Pages: IX, 339 p. 7 illus., 4 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811525179
    Series Statement: Advances in Experimental Medicine and Biology, 1177
    DDC: 615
    Language: English
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  • 2
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Pharmacology. ; Pharmaceutics.
    Description / Table of Contents: 1 Principles of pharmaceutical analysis in drug stability and chemical kinetics -- 2 Guidelines for drug stability and stability testing -- 3 Chemical kinetics and its applications in drug stability -- 4 Methods and protocols for drug stability studies -- 5 Physical basis of degradation of pharmaceutical products -- 6 Role of microbiological degradation on drug stability -- 7 Role of decomposition on drug stability -- 8 Role of catalysis in drug stability -- 9 Analytical techniques for the assessment of drug stability -- 10 Stability of pharmaceutical products -- 11 Role of kinetic models in drug stability -- 12 Stability studies of vaccines -- 13 Stability studies of proteinous compounds -- 14 Stability studies of extemporaneous pharmaceutical products -- 15 Stability studies of parenteral products -- 16 Stability studies of solid dosage forms.
    Abstract: This book comprehensively reviews drug stability and chemical kinetics: how external factors can influence the stability of drugs, and the reaction rates that trigger these effects. Explaining the important theoretical concepts of drug stability and chemical kinetics, and providing numerous examples in the form of illustrations, tables and calculations, the book helps readers gain a better understanding of the rates of reactions, order of reactions, types of degradation and how to prevent it, as well as types of stability studies. It also offers insights into the importance of the rate at which the drug is degraded and/or decomposed under various external and internal conditions, including temperature, pH, humidity and light. This book is intended for researchers, PhD students and scientists working in the field of pharmacy, pharmacology, pharmaceutical chemistry, medicinal chemistry and biopharmaceutics. .
    Type of Medium: Online Resource
    Pages: XIV, 284 p. 22 illus., 13 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811564260
    DDC: 615
    Language: English
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  • 3
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Nutrition   . ; Food science. ; Pharmacology. ; Nutrition. ; Food Science.
    Description / Table of Contents: 1 Preface -- 2 Effects of Nutrients/nutrition on Toxicants/toxicity -- 3 Effects of Xenobiotics on Nutrition -- 4 Effects of Antinutritional Factors on the Digestibility, Bioavailability and Quality of Protein -- 5 Natural Toxicants Originating from Food/Diet -- 6 Food contaminants -- 7 Food additives -- 8 Food contact materials -- 9 Genetically modified food -- 10 Tolerable upper limits of nutrients -- 11 Risk assessment and Risk-benefit assessment -- 12 Nutrients/Nutrition and Drug Interaction -- 13 Phytochemicals and Health -- 14 Adverse Effects of Phytochemicals.
    Abstract: This book provides a broad overview of the chemicals in food that have the potential to induce adverse health effects. Nutritional Toxicology is an interaction of nutrition, toxicology, biochemistry and food science, etc. Its main research scope involves the effects of nutrients on metabolisms of toxicants and their mechanisms, the interaction of the toxicants and contaminants originated from diet with nutrients and nutrition process, the adverse health outcome of nutrients excess, as well as methodology of research and related food and nutrition regulation process. Also the risk assessment of toxicants and contaminants in foods, and risk benefit assessment of nutrients (dietary supplementation) has become an emerging topic. This book provides novel and provocative insights into the fields of nutrition, food science and toxicology. It also offers a state-of-the-art report on recent discoveries concerning nutritional toxicology and where the field is going. It mainly focuses on advances made over the past 20 years. It will benefit graduate students, researchers and food and nutrition related regulation parties.
    Type of Medium: Online Resource
    Pages: X, 384 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811908729
    DDC: 615
    Language: English
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  • 4
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Pharmacy. ; Bioinformatics. ; Pharmacology. ; Pharmacy. ; Bioinformatics.
    Description / Table of Contents: Chapter 1. 'Network Target' Theory and Network Pharmacology -- Chapter 2. Application of Network Pharmacology Based on Artificial Intelligence Algorithm in Drug R & D -- Chapter 3. Commonly used Network Pharmacology Database -- Chapter 4. Commonly used Network Pharmacology Software -- Chapter 5. Network Pharmacology and TCM Modernization Case Studies -- Chapter 6. Network Pharmacology and Modern Drug R & D Cases -- Chapter 7. Drug-based Network Pharmacology Practice Process -- Chapter 8. Disease-based Network Pharmacology Practice Process -- Chapter 9. Drug-disease-based Network Pharmacology Practice Process.
    Abstract: This book introduces “network pharmacology” as an emerging frontier subject of systematic drug research in the era of artificial intelligence and big data. Network Pharmacology is an original subject of fusion system biology, bioinformatics, network science and other related disciplines. It emphasizes on starting from the overall perspective of the system level and biological networks, the analysis of the laws of molecular association between drugs and their treatment objects, reveals the systematic pharmacological mechanisms of drugs, and guides the research and development of new drugs and clinical diagnosis and treatment. After it was proposed, network pharmacology has been paid attention by researchers, and it has been rapidly developed and widely used. In order to systematically reveal the biological basis of diagnosis and treatment in traditional Chinese medicine and modern medicine, we proposed a new concept of "network target" for the first time, which has become the core theory of "network pharmacology". The core principle of a network target is to construct a biological network that can be used to decipher complex diseases. The network is then used as the therapeutic target, to which multicomponent remedies are applied. This book mainly includes four parts: 1) The concept and theory of network pharmacology; 2) Common analysis methods, databases and software in network pharmacological research; 3) Typical cases of traditional Chinese medicine modernization and modern drug research based on network pharmacology; 4) Network pharmacology practice process based on drugs and diseases.
    Type of Medium: Online Resource
    Pages: XVII, 468 p. 163 illus., 119 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811607530
    DDC: 615
    Language: English
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  • 5
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Midwifery. ; Public health. ; Pharmacology. ; Midwifery. ; Public Health.
    Description / Table of Contents: Part I Environmental Harmful Factors -- 1 Introduction to Environmental Harmful Factors -- Part II Female Reproductive Processes and Diseases -- 2 Introduction of Female Reproductive Processes and Reproductive Diseases -- Part III Effects of Environmental Factors on Reproductive Process -- 3 The Influence of Environmental Factors on Ovarian Function, Follicular Genesis, and Oocyte Quality -- 4 Effects of environment and lifestyle factors on premature ovarian failure -- 5 Effects of Environment and Lifestyle Factors on Anovulatory Disorder -- 6 Effects of Cigarette Smoking on Preimplantation Embryo Development -- 7 Toxicical effects of BPDE on dysfunctions of female trophoblast cells -- 8 The Roles of Stress-Induced Immune Response in Female Reproduction -- 9 Effects of Environmental EDCs on Oocyte Quality, Embryo Development and the Outcome in Human IVF Process -- Part IV Effects of Environmental Factors on Reproductive Diseases -- 10 Effects of environmental endocrine-disrupting chemicals on female reproductive health -- 11 Definition and Multiple Factors of Recurrent Spontaneous Abortion -- 12 The Variations of Metabolic Detoxification Enzymes Lead to Recurrent Miscarriage and their Diagnosis Strategy -- Part V Effects of Environmental Factors on Fertility Preservation -- 13 The Effects of Negative Elements in Environment and Cancer on Female Reproductive System.
    Abstract: This book will focus on the harmful effect of environmental toxins on female reproductive health. Reproduction is the basis of the continuation of human beings, and environment is the basis of human survival. However, environmental pollution has become a potential risk factor for human reproductive health, which not only leads to many chronic diseases, but also causes certain harm to reproductive health. Compared to male reproduction, female reproductive process is more complex, the reproductive system is more fragile, and is more vulnerable to be damaged. The aim of this book is to review the research progress, to address the challenges, and to stimulate the development in the direction of environment and female reproductive health.
    Type of Medium: Online Resource
    Pages: XI, 313 p. 13 illus., 10 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813341876
    Series Statement: Advances in Experimental Medicine and Biology, 1300
    DDC: 615
    Language: English
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  • 6
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Veterinary medicine. ; Animal biotechnology. ; Nanobiotechnology. ; Veterinary Science. ; Animal Biotechnology. ; Nanobiotechnology.
    Description / Table of Contents: Chapter 1_Introduction -- Chapter 2_Application of ultrasonography in bovine reproduction -- Chapter 3_Infrared thermal imaging and its application in animal reproduction. -Chapter 4_Technological advancements for early pregnancy diagnosis in cattle and buffaloes -- Chapter 5_Bull sperm selection for assisted reproduction -- Chapter 6_Nano purification of semen: A novel technique for enrichment of superior quality spermatozoa. -Chapter 7_Sperm transcriptome sequencing for predicting bull Fertility-Concepts, facts and future directions -- Chapter 8_Semen proteomics and metabolomics: Emerging tools for discovering fertility markers -- Chapter 9_Spermatogonial stem cells: Their use in fertility restoration -- Chapter 10_Multiple Ovulation and Embryo Transfer in Livestock Production -- Chapter 11_Ovum pick-up and in vitro embryo production in bovine -- Chapter 12_Milestones and recent developments in farm animal cloning -- Chapter 13_Advances and applications of transgenesis in farm animals -- Chapter 14_Offspring sex pre-selection in mammals: An Update -- Chapter 15_Genomic selection of bovines for fertility -- Chapter 16_Prospects of Stem Cells in Fertility Management in Bovine -- Chapter 17_Conclusion.
    Abstract: This book details the frontier technologies in the area of bovine reproduction. It describes the importance and significance of different technologies for improving reproduction efficiency in bovines. The book delineates the advancements in the technologies that are currently in use for faster multiplication of elite germ plasm including multiple ovulation and embryo transfer, ovum-pick-up, in vitro fertilization and embryo production, and semen sexing. Other emerging technologies, having potential for improving reproductive efficiency in bovines, including stem cells are also discussed with special reference to spermatogonial stem cells. Simple but effective tools having a great scope for day-to-day application in bovine farms for effective reproductive management like ultrasonography and thermal imaging are also covered in this book. The chapters on sperm transcriptomics, proteomics, metabolomics provide current developments in these areas and use of integrated approach for identification of fertility biomarkers. The chapters also describe technological advancements for early pregnancy diagnosis and offspring sex pre-selection in bovines. Additionally, this book discusses different sperm selection procedures including application of nanotechnology to obtain superior spermatozoa for assisted reproduction. Futuristic technologies including genomic selection and transgenesis are also discussed in detail. Finally, the book also elucidates a comprehensive description of challenges perceived with bovine reproduction and how effectively these technologies can help in improving fertility in bovines.
    Type of Medium: Online Resource
    Pages: X, 341 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811930720
    DDC: 636.089
    Language: English
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  • 7
    Keywords: Pharmacology. ; Nanobiotechnology. ; Biomedical engineering. ; Drug delivery systems. ; Pharmaceutical chemistry. ; Pharmacology. ; Nanobiotechnology. ; Biomedical Engineering and Bioengineering. ; Drug Delivery. ; Pharmaceutics.
    Description / Table of Contents: Chapter 1. An introduction to respiratory diseases and an emerging need for efficient drug delivery systems -- Chapter 2. Inflammatory respiratory diseases: Correlation between Lung cancer and CoVid-19 -- Chapter 3. Advancements in translational respiratory research using nanotechnology -- Chapter 4. Chemical moieties as advanced therapeutics for targeting respiratory disorders -- Chapter 5. Phytochemicals and their nanoformulations targeted for pulmonary diseases -- Chapter 6. Nanocarriers: an advanced and highly effective approach for targeting chronic lung diseases -- Chapter 7. Vesicular drug delivery systems in respiratory diseases -- Chapter 8. Nanoparticles in chronic respiratory diseases -- Chapter 9. Applications of nanotechnology in pulmonary disease diagnosis -- Chapter 10. Nanotechnology in pulmonary disease diagnosis -- Chapter 11. Recent trends in Nanomedicine for diagnosis and treatment of pulmonary diseases -- Chapter 12. Strategies for enhanced drug targeting to inflamed lungs: Novel perspectives -- Chapter 13. Solid-Lipid Nanocarriers (SLN’s) based drug delivery for treating various pulmonary diseases -- Chapter 14. Microparticles, microspheres and microemulsions as pulmonary drug delivery systems for the treatment of respiratory diseases -- Chapter 15. Microparticles, microspheres and microemulsions in respiratory diseases -- Chapter 16. Advanced drug delivery systems targeting the immune system at cellular level in chronic respiratory diseases -- Chapter 17. Targeted Micellar Systems for Pulmonary Disease Intervention -- Chapter 18. Polymeric and inorganic nanoparticles targeting chronic respiratory diseases -- Chapter 19. Mucoadhesive drug delivery system in chronic respiratory diseases -- Chapter 20. Liposomal Drug Delivery: Therapeutic Applications in Chronic Respiratory Diseases -- Chapter 21. Biologics and vaccines for nasal and pulmonary drug delivery -- Chapter 22. Drug delivery systems for respiratory infections -- Chapter 23. Cell and Gene Therapies for Chronic Inflammatory Lung Diseases - Emerging Technological Trends and Advancements in Respiratory Medicine -- Chapter 24. Targeting biofilms in respiratory diseases using novel drug delivery systems -- Chapter 25. Advanced nanomaterials for drug delivery in chronic respiratory disorders -- Chapter 26. Emerging technological trends and advancements in respiratory medicine -- Chapter 27. Pulmonary pharmacokinetics and Biophysics -- Chapter 28. Clinical trials on novel advanced drugs for chronic respiratory disorders.
    Abstract: This book describes the growing clinical and healthcare relevance of nano-therapeutics in treating respiratory diseases. It begins with a brief introduction on the different types of nanoparticles in respiratory disease conditions. It further discusses the current trends in understanding the disease pathology using different in vitro and in vivo models, which are important towards the onsite clinical applications and development of new therapeutics. The book includes exciting topics such as formulation of these nanoparticles, targeting various organelles etc. It also describes the future prospects and challenges in the field. Different chapters are written by researchers actively working in the area of pulmonary diseases. This book is designed to address the requirements of both beginners and specialized scientists involved in pulmonary research. The contents include basic concepts followed by advanced state-of-art monitoring and treatment of diseases. The book is meant for researchers and industry experts in nanotechnology, pharmaceutical sciences and drug design.
    Type of Medium: Online Resource
    Pages: X, 655 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811643927
    DDC: 615
    Language: English
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  • 8
    Keywords: Pharmacology. ; Cancer. ; Cancer Treatment. ; Pharmacology. ; Cancers. ; Cancer Therapy.
    Description / Table of Contents: Chapter 1_Introduction to Cancer -- Chapter 2_Effect of anticancer treatment approches on gut microbiota -- Chapter 3_Synbiotic: A promising approach for the treatment of cancer -- Chapter 4_Correlation between ROS and Synbiotics for effective treatment of cancer -- Chapter 5_Influence of synbiotics on inflammation and immune microenvironment for the treatment of cancer -- Chapter 6_Synbiotics in colorectal cancer -- Chapter 7_Synbiotics in cervical cancer -- Chapter 8_Synbiotics in prostate cancer -- Chapter 9_Synbiotics in gastric cancer -- Chapter 10_Synbiotics in lung cancer -- Chapter 11_Synbiotics in small cell pancretatic cancer -- Chapter 12_Synbiotics in breast cancer -- Chapter 13_Synbiotics in hepatocellular carcinoma -- Chapter 14_Synbiotics in ovarian cancer -- Chapter 15_Regulatory issues of synbiotics in cancer.
    Abstract: This book illustrates the significance of probiotics and prebiotics for the management of various types of cancers. The up-to-date chapters provide recent information about the effect of anticancer treatment approaches on gut microbiota, the correlation between ROS and synbiotics for effective cancer treatment, and the influence of synbiotics on inflammation and immune microenvironment for cancer treatment. It also describes the regulatory issues about synbiotics in the management of cancer. This book is an essential resource for scientists working in the field of cancer, pharmaceutical & clinical sciences, and cancer clinicians. This book is also very useful for undergraduate and postgraduate students of Pharmacy and Biotechnology and medical researchers, mainly working in microbiology, immunology, and cancer biology.
    Type of Medium: Online Resource
    Pages: XVII, 340 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811975509
    DDC: 615
    Language: English
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  • 9
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Nanobiotechnology. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery. ; Nanobiotechnology.
    Description / Table of Contents: Part 1. Pharmaceutical Innovation and Research -- Chapter 1. Innovation in stabilization of biopharmaceuticals -- Chapter 2. Concepts in pharmacogenomics: tools and applications -- Chapter 3. Pharmacogenetics–a new approach for the selection of the right drug -- Chapter 4. Meeting the unmet challenges of pharmaceutical research using artificial intelligence -- Chapter 5. Pharmaceutical innovation and research in ayurved -- Chapter 6. Ayurveda intervention in perimenopausal syndrome -- Part 2. Drug Discovery and Development -- Chapter 7. Innovative strategies in drug discovery and pharmacoinformatics -- Chapter 8. Advances in peptide synthesis -- Chapter 9. Peptidomimetics in Medicinal Chemistry: The Art of Transforming Peptides to Drugs -- Chapter 10. Diverse Pharmacological Activities of 4-aminoquinoline and its Derivatives -- Chapter 11. Thiourea catalysts for synthesis of active pharmaceutical ingredients -- Chapter 12. The Chemistry and Pharmacology of Mandarin Orange -- Chapter 13. Recent progress in the pharmacology of phytoestrogens: emerging neuromodulators for treating anxiety and depression -- Chapter 14. Next-generation cell-based therapies to combat metastaticbrain tumor -- Chapter 15. Pharmacokinetics and Pharmacodynamics: Fundamentals and Role(s) in Drug Discovery and Development -- Chapter 16. An update on pharmacokinetic models -- Chapter 17. Pharmacodynamics: Basics and Applications in Drug Research -- Part 3. Drug Delivery and Nanotechnology -- Chapter 18. Technological innovations in pharmaceutical drug nanocrystals -- Chapter 19. Fixed Dose Combinations: Innovations and Research -- Chapter 20. Significance of Intranasal Drug Delivery Systems: Recent Trends and Clinical Investigations in Brain Disorders -- Chapter 21. Current challenges and nanotechnology-based pharmaceutical approaches for the treatment and control of visceral leishmaniasis -- Chapter 22. Polymeric Nanoparticles-based Drug Delivery Systems for Anticancer Therapy. Chapter 23. Carbon nanotubes: a review of toxicity and applicability in biomedical applications -- Chapter 24. Recent trends in topical herbal nanotherapeutics for psoriasis -- Part 4. Pharmaceutical Microbiology -- Chapter 25. Antibiotics: past, present, future, and clinical pipeline -- Chapter 26. Innovative strategies to tackle antimicrobial resistance -- Chapter 27. Molecular and mechanistic insights of yeast flocculation -- Chapter 28. Management of hepatitis virus C: current and future treatments -- Chapter 29. Tuberculosis: experimental models, innovations and challenges -- Chapter 30. Targeting outer membrane to tackle multi-drug resistant bacterial pathogens -- Chapter 31. Diphtheria-A Paradigmatic Vaccine Preventable Toxigenic Disease with Changing Epidemiology -- Chapter 32. Emerging and re-emerging infections: an overview.
    Abstract: This book covers several important aspects of pharmaceutical research and innovations. It presents important topics on drug delivery, novel microsponge, nanocrystals, polymeric nanoparticles, peptide synthesis, biopharmaceuticals, pharmacodynamics, yeast flocculation, neuromodulators, innovative drug discovery, pharmacoinformatics, aminoquinoline, thiourea crystals for API synthesis, FDCs and formulations research, ayurveda and natural products, and innovations to militate anti-microbial resistance (AMR). A chapter is devoted to the applications of Artificial Intelligence and Machine Learning in diverse sectors of the pharmaceutical industry, including drug discovery and development, drug repurposing, and improving pharmaceutical productivity. The book also reviews the role of pharmacogenomics and pharmacogenetics in drug development and precision medicine. Further, the book presents an updated summary of recent advances in the fields of nanomedicines and nano-based drug delivery systems. This book is useful to pharmaceutical sciences students, researchers, educators, and professionals in the pharmaceutical industry to understand the intricacies of new drug research and innovations.
    Type of Medium: Online Resource
    Pages: XXI, 770 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819923021
    DDC: 615
    Language: English
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  • 10
    Keywords: Pharmacology. ; Nanobiotechnology. ; Drug delivery systems. ; Pharmacology. ; Nanobiotechnology. ; Drug Delivery.
    Description / Table of Contents: Ch 1 Introduction to block co-polymers -- Ch 2 Role of block co-polymers in drug delivery -- Ch 3 Role of block co-polymers in enhancement of poor solubility of drugs -- Ch 4 Synthesis and Self–assembly of block copolymers -- Ch 5 Role of block co-polymers in treatment of brain disorders -- Ch 6 Role of block co-polymers in treatment of neurodegenerative disorders -- Ch 7 Role of block co-polymers in colon cancer -- Ch 8 Role of block co-polymers in lung cancer -- Ch 9 Role of block co-polymers in IBD -- Ch 10 Role of block co-polymers in vaccine -- Ch 11 Role of block co-polymers in treatment of GIT disorders -- Ch 12 Role of block co-polymers in topical drug delivery -- Ch 13 Role of block co-polymers in targeted drug delivery -- Ch 14 Role of block co-polymers in ocular drug delivery -- Ch 15 Role of block co-polymeric micelles in drug delivery -- Ch 16 Applications of block co-polymers as Stimuli Responsive Copolymers -- Ch 17 Patented block co-polymers for various Therapeutics Applications.
    Abstract: This book focuses on current advancements in the field of block copolymers and covers design, concept, and various therapeutic applications in the drug delivery. It also reviews the use of block copolymers in drug delivery applications from the development of sustained release products to smart polymeric delivery systems such as stimuli-responsive polymeric systems, for example, thermosensitive, redox-sensitive, photo-sensitive, and enzyme-sensitive. The book further discusses the nano assemblies from amphiphilic block copolymers as nanomedicine platforms for diagnosis and therapy due to their relatively small size, high drug loading capacity, controlled drug release, in vivo stability, and prolonged blood circulation. The chapters also review the various patents and ongoing clinical trials on the applications, covering several important new concepts and findings in the field of block copolymers. The book is aimed at researchers, academicians, and industrial scientists involved in the development of drug-delivery systems based on polymers.
    Type of Medium: Online Resource
    Pages: XVII, 429 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819969173
    DDC: 615
    Language: English
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  • 11
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Nanobiotechnology. ; Nanomedicine. ; Pharmacology. ; Nanobiotechnology. ; Nanomedicine and Nanotoxicology.
    Description / Table of Contents: Chapter 1. Macroporous cryogel-based systems for water treatment applications and Safety: nanocomposite-based cryogels and bacteria-based bioreactors -- Chapter 2. One dimensional Semiconducting Nanomaterials: Toxicity and Clinical Applications -- Chapter 3. Prospects of Safe use of Nanomaterials in Biomedicalapplications -- Chapter 4. Hyaluronic acid-based nanotechnologies for delivery and treatment -- Chapter 5. Theranostics nanomaterials for safe cancer treatment -- Chapter 6. Cardiovascular safety assessment of new chemical entities: current perspective and emerging technologies -- Chapter 7. Toxicology of pharmaceutical products during drug development -- Chapter 8. Safety and Risk assessment of food items -- Chapter 9. Non toxic Natural products as regulators of tumour suppressor gene function -- Chapter 10. Advancements in the safety of Plant medicine: Back to nature -- Chapter 11. Chemicals and their interaction in the aquaculture system -- Chapter 12. Zebrafish as a biomedical model to define developmental origins of chemical toxicity -- Chapter 13. Green synthesis of non toxic nanoparticles -- Chapter 14. Synthesis, characterisation and safety of titanium oxide nanoparticles -- Chapter 15. Characterisation of non toxic nanomaterials for biological applications -- Chapter 16. Toxicity assessment of nanoparticle -- Chapter 17. Safety of nanoparticles: emphasis on antimicrobial properties -- Chapter 18. Quantum dots for imaging and its safety -- Chapter 19. Genotoxicity evaluation of nanosized materia -- Chapter 20. Scaffoldmaterials and toxicity -- Chapter 21 Biological Safety and Cellular interactions of nanoparticles -- Chapter 22. Role of artificial intelligence in the toxicity prediction of drugs -- Chapter 23. Chemicals and rodent models for the safety study of alzheimer’s disease -- Chapter 24. Mitochondria-targeted liposomal delivery in Parkinson's disease: safety concerns -- Chapter 25. Routes of Nano-drug Administration and Nano-based drug delivery system and toxicity -- Chapter 26. Green Synthesised silver nanoparticles phytotoxicity and applications in agriculture: An overview -- Chapter 27 status of safety concerns of microplastic detection strategies -- Chapter 28. Impact of insecticides on man and environment.
    Abstract: This book covers the recent trends on the biological applications of nanomaterials, methods for their preparation, and techniques for their characterization. Further, the book examines the fundamentals of nanotoxicity, methods to assess the toxicity of engineered nanomaterials, approaches to reduce toxicity during synthesis. It also provides an overview of the state of the art in the application of Artificial intelligence-based methodologies for evaluation of toxicity of drugs and nanoparticles. The book further discusses nanocarrier design, routes of various nanoparticle administration, nano based drug delivery systems, and the toxicity challenges associated with each drug delivery method. It presents the latest advances in the interaction of nanoparticles with the cellular environment and assess nanotoxicity of these engineered nanoparticles. The book also explores the comparative and mechanistic genotoxicity assessment of the nanomaterials. This book is useful source of information for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, and drugs.
    Type of Medium: Online Resource
    Pages: XVIII, 768 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811978340
    DDC: 615
    Language: English
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  • 12
    Keywords: Pharmacology. ; Medicinal chemistry. ; Pharmaceutical chemistry. ; Biotechnology. ; Biochemical engineering. ; Pharmacology. ; Medicinal Chemistry. ; Pharmaceutics. ; Biotechnology. ; Bioprocess Engineering.
    Description / Table of Contents: Preface -- General principles of chirality -- Quantitative methods of analysing chirality drugs - Chirality and pharmacokinetics -- Drugs regulating the function of peripheral nervous system -- In silico search for chiral drug compounds.
    Abstract: The book is devoted to an important aspect of pharmacology and pharmaceutical chemistry, i.e. the significance of stereoisomerism of drugs for their biological effect from the point of view of their pharmacokinetics, pharmacodynamics and toxicology. The authors review the landmarks in the development of stereochemistry and stereopharmacology. Present-day IUPAC terminology is discussed; general issues of stereoisomerism are considered including separation of racemic mixtures and asymmetric synthesis of isomers, methods of quantifying the isomers of a drug in biological material. The authors put special emphasis on general problems of the influence of stereoisomerism on pharmacological and adverse effects of drugs. A classification of drugs based on stereochemical properties of their isomers is proposed. Possibilities of interaction of stereoisomers in racemic mixtures are discussed. A considerable portion of the book is devoted to pharmacological action of the main groups of drugs whose structure includes asymmetric atoms (that is, drugs with several isomers). Detailed attention is paid to advisability of developing single isomer drugs and to the specifics of their study at the stage of preclinical and clinical trials.
    Type of Medium: Online Resource
    Pages: XI, 207 p. 174 illus., 6 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811923203
    Series Statement: Progress in Drug Research, 76
    DDC: 615
    Language: English
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  • 13
    Keywords: Veterinary medicine. ; Epidemiology. ; Public health. ; Veterinary Science. ; Epidemiology. ; Public Health.
    Description / Table of Contents: Chapter 1-Veterinary Public Health -- Chapter 2-Zoonoses -- Chapter 3- Epidemiology -- Chapter 4- Ecological concepts -- Chapter 5- Causation of disease -- Chapter 6-Agent, Host and Environmental Factors -- Chapter 7-Disease Transmission -- Chapter 8-Disease Distribution in Population -- Chapter 9-Data in Epidemiology -- Chapter 10-Measures of Disease -- Chapter 11-Strategies of Epidemiology -- Chapter 12-Sampling Techniques -- Chapter 13-Measurement of Causal association -- Chapter 14-Investigation of an outbreak -- Chapter 15-Diagnostic test and its evaluation -- Chapter 16-Surveillance -- Chapter 17- Prevention, Control and Eradication -- Chapter 18-Economics of Disease -- Chapter 19-World Organization for Animal Health (WOAH) -- Chapter 20-Food borne infection & intoxication -- Chapter 21-Investigation of Foodborne outbreak – Source attribution -- Chapter 22-Viral infections-Norwalk -- Chapter 23-Hepatitis A -- Chapter 24-Hepatitis E -- Chapter 25-Rota virus -- Chapter 26-PRIONS/BSE -- Chapter 27-Viruses occasionally reported as foodborne -- Chapter 28- Foodborne Bacterial Infections-Salmonellosis -- Chapter 29-Escherchia coli -- Chapter 30-Klebsiella -- Chapter 31-Aeromonas hydrophila -- Chapter 32-Staphylococcus spp -- Chapter 33-Streptococcus suis -- Chapter 34-Clostridium perfringens -- Chapter 35-Botulism -- Chapter 36-Campylobacteria -- Chapter 37-L. monocytogenes -- Chapter 38-Bacillus cereus -- Chapter 39-Food borne parasites -- Chapter 40-One Health.
    Abstract: This book introduces and reviews the essential principles of Veterinary Public Health, Zoonoses, One Health, principles and applications of epidemiology in studying infectious diseases including foodborne infections and intoxications.The initial chapters discuss the concept and principal functions of Veterinary Public Health. The book further covers the impacts of Veterinary Public Health on human Health particularly in management of zoonoses. The following section discusses theapplication of epidemiology in the study of outbreaks, epidemic, pandemics and their prevention and control strategies. It helps understanding the factors associated with disease causation transmission and spread and also investigate the emergence of antimicrobial resistance. The chapter on foodborne illnesses illustrates how the knowledge of epidemiology is applied in the study of diseases in community, spread of causative agents from farm to fork. The definition, cause, symptoms, management, control and prevention of foodborne infection and intoxication are dealt with. The last chapter introduces the concept, objectives, and definition of One Health and discusses the advancements made and challenges in One Health around endemic and emerging zoonotic diseases. .
    Type of Medium: Online Resource
    Pages: XXIX, 424 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811978005
    DDC: 636.089
    Language: English
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  • 14
    Keywords: Pharmacology. ; Clinical medicine Research. ; Medicine Research. ; Biology Research. ; Pharmacology. ; Clinical Research. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. Potentiality of Probiotics in Inactivation of Tetrodotoxin -- Chapter 2. Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics -- Chapter 3. Plant based Bioactive compounds in Cancer Therapeutics -- Chapter 4. Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics -- Chapter 5. Probiotics as efficacious therapeutic option for treating gut-related diseases: molecular and immunobiological perspectives -- Chapter 6. The progressive development of probiotics, prebiotics, synbiotics research, and its multipurpose use in the ornamental fishery -- Chapter 7. The commercial perspective of probiotics, and bioremediating components in aquaculture pond management: A Case Study -- Chapter 8. Prebiotics as promising therapeutics for treating gut-related disorders : Biochemical and Molecular Perspectives -- Chapter 9. Prebiotics and Probiotics as Functional Foods: Prospect and Promises in Metabolic Diseases. Chapter 10. Implications of probiotics and prebiotics on immune functions -- Chapter 11. Recent Trends in Natural Medicines and Nutraceuticals Research -- Chapter 12. Nutraceuticals-are alternative to modern medicines- Chapter 13. Socio-Economic Study of Prospective of probiotic, prebiotic and synbiotic for sustainable development of aquaculture in Indian Sunderban -- Chapter 14. Drosophila melanogaster as an in-vivo model for the investigation of host microbiota interaction -- Chapter 15. Prospectives of Prebiotics, Probiotics and Synbiotics for Sustainable Development of Aquaculture.
    Abstract: The book titled ‘Prebiotics, Probiotics and Nutraceuticals’ is expected to direct many emerging research pathwaysneed at local and global levels for nutrition and food supplements for developing immunity for healthy life. This volume incorporates sixteen seminal papers on issue based research and their practical applications covering latest information and progress on different area of nutritional supplement research fight against disease. The book highlights the frontier issues and applications in nutritional biotechnology with wide coverage of the themes like Potentiality of Probiotics in Inactivation of Tetrodotoxin, Therapeutic Strategy for the Deterrence of COVID-19 with Relevance to Probiotics and Prospectives of Prebiotics, Probiotics and Synbiotics for Sustainable Development in Aquaculture.Plant based Bioactive compounds in Cancer Therapeutics, Recent Trends in Natural Medicines and Nutraceuticals Research, Probiotics as efficacious therapeutic option for treating gut-related diseases: molecular and immune-biological perspectives, The progressive development of probiotics, prebiotics, synbiotics research, and its multipurpose use in the ornamental fishery, The commercial perspective of probiotics, and bioremediating components in aquaculture pond management: A Case Study andPrebiotics as promising therapeutics for treating gut-related disorders : Biochemical and Molecular Perspectives. Prebiotics and Probiotics as Functional Foods: Prospect and Promises in Metabolic Diseases, Implications of probiotics and prebiotics on immune functions. Recent Trends in Natural Medicines and Nutraceuticals Research, Nutraceuticals are alternative to modern medicines, Socio-Economic Study of Prospective of probiotic, prebiotic and synbiotic for sustainable development of aquaculture in Indian Sunderban. This book will be very useful for the scholars, biotechnologists, agricultural scientists, nutritionist, medical doctors, researchers, teachers and students in the emerging field of biotechnology.
    Type of Medium: Online Resource
    Pages: XVI, 340 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811689901
    DDC: 615
    Language: English
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  • 15
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Veterinary medicine. ; Animal biotechnology. ; Diagnosis. ; Animal culture. ; Veterinary Science. ; Animal Biotechnology. ; Diagnosis. ; Animal Science.
    Description / Table of Contents: Chapter 1_Introduction -- Chapter 2_Reproduction efficiency in bovine: Trend and targets -- Chapter 3_Advancing puberty and sexual maturity: Recent developments -- Chapter 4_Automation in estrus detection -- Chapter 5_Salivary fern pattern and microRNAs for estrus detection -- Chapter 6_Timed AI and estrus synchronization in bovine animals: Advancements in protocols -- Chapter 7_Uterine infection in bovines -- Chapter 8_Endometrial TLRs and post-partum uterine infection in bovine -- Chapter 9_Nutritional strategies to improve bovine reproduction -- Chapter 10_Advances in understanding the mechanism of MRP in bovine -- Chapter 11_Metabolic hormones: Influence on gonadal functions and fertility in bovine -- Chapter 12_Recent developments in semen cryopreservation and frozen semen quality control -- Chapter 13_Advanced in vitro sperm function tests for fertility prediction -- Chapter 14_Sperm transcriptome sequencing for bovine fertility prediction: Lesson learned -- Chapter 15_Post-translational modifications in spermatozoa and fertility -- Chapter 16_Epigenetic bearing on fertility in bovine -- Chapter 17_Conclusion.
    Abstract: This book provides updated information on the current concepts in bovine reproduction. It describes the complex issues associated with fertility and infertility in bovines and suggests strategies for achieving high reproductive efficiency. It discusses topics related to the fertility trend in bovines, estrus detection, controlled breeding, postpartum uterine health, uterine infections, and its therapeutic management. The essential roles of metabolic hormones on gonadal functions and fertility are also covered. Additionally, the book presents new insights in maternal recognition of pregnancy in bovines and suggest nutritional strategies to improve reproductive efficiency. The chapters on male fertility provide current information on semen cryopreservation, sperm quality assessment and measures to improve sperm fertility. A special chapter on intricacies in buffalo semen cryopreservation and measures to improve the quality of cryopreserved sperm is also included in this book. Lastly, the book introduces the immunobiological roles of anti-microbial peptides during sperm transport in reproductive tract and epigenetic bearing on fertility. This book is an invaluable resource for veterinary scientists, students and practitioners to understand the current developments in bovine reproduction for improving reproductive efficiency.
    Type of Medium: Online Resource
    Pages: X, 342 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811901164
    DDC: 636.089
    Language: English
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  • 16
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Botanical chemistry. ; Bioorganic chemistry. ; Pharmacology. ; Plant Biochemistry. ; Bioorganic Chemistry.
    Description / Table of Contents: Chapter 1. Introduction of diabetes melitus and future prospects of natural products on diabetes melitus -- Chapter 2. Anoverview of hypoglycemic modern drugs -- Chapter 3. An overview of hypoglycemic biological drugs -- Chapter 4. An overview of hypoglycemic traditionaldrugs -- Chapter 5. Glycosides from natural sources in the treatment of diabetes mellitus -- Chapter 6. Isolation and Structure Elucidation of Hypoglycemic Compounds -- Chapter 7. Structural Characterization and Health Effects of Polysaccharides from Momordica charantia on Diabetes Mellitus -- Chapter 8. Effects of polysaccharides on reducing blood glucose based on gut microbiota alteration -- Chapter 9. An Overview of Polysaccharides and the influencefactors of Hypoglycemic Activity -- Chapter 10. Plant Secondary Metabolites with α-Glucosidase Inhibitory Activity. - Chapter 11. Rhinacanthin-C and Its Potential to Control Diabetes Mellitus -- Chapter 12. Regeneration of beta cells by inhibition of pro-apoptotic proteins through phytocompound in STZ induced diabetic albino wistar rats-invivo and insilico approach. - Chapter 13. Nitrogenous Compounds from Plant Origin in Management of -- Chapter 14. Plant Alkaloids with Antidiabetic Potential -- Chapter 15. The role of Alkaloids in the Management of Diabetes Mellitus -- Chapter 16. Traditional Indian Herbs for the Management of Diabetes Mellitus and their Herb-Drug Interaction Potentials: An Evidence-Based Review -- Chapter 17. Role of Micronutrients and Trace elements in Diabetes mellitus: A Review.
    Abstract: The purpose of this book is to introduce the classified chemical components of hypoglycemic compounds in natural products, summarize the recent research progress of natural products with hypoglycemic activity in the past 20 years, and provide the original analysis and development opinions of relevant scholars. Hypoglycemic compounds are to target diabetes mellitus, an important public health problem, one of four priority noncommunicable diseases (NCDs) targeted for action by world leaders. Diabetes mellitus is a common endocrine and metabolic disease, which not only causes physiological damage to patients' kidneys, cardiovascular and cerebrovascular vessels, peripheral blood vessels, nerves and eyes, but also causes mental and psychological pressure to patients. Due to the evidence that traditional medicine and natural herbal formula have advantages in treating diabetes, natural products with hypoglycemic activity have been studied extensively in recent years and have been accepted by many scholars all over the world. This book focuses on the progress on the study of the structure, hypoglycemic activities, structure-activity relationships and mechanism of a wide range of polysaccharides, flavonoids, saponins, alkaloids, terpenoids, polyphenols and other constituents. It will help students and researchers to understand current approaches and progress in the treatment of diabetes with natural products, which may also be beneficial to develop new hypoglycemic drugs.
    Type of Medium: Online Resource
    Pages: VIII, 307 p. 85 illus., 16 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811587917
    DDC: 615
    Language: English
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  • 17
    Keywords: Pharmacology. ; Medical microbiology. ; Medicinal chemistry. ; Pharmacovigilance. ; Pharmacology. ; Medical Microbiology. ; Medicinal Chemistry. ; Drug Safety and Pharmacovigilance.
    Description / Table of Contents: Chapter 1. Global Approach for Drug Discovery and Development from Indian Traditional Medicine -- Chapter 2. Bioactive Natural Leads TargetingCancer Cell Metabolism -- Chapter 3. Omics Technologies and Development of Anti-diabetic Therapies from Prospective Natural Products -- Chapter 4. Amaryllidaceae Alkaloids as Anti-inflammatory Agents Targeting Cholinergic Anti-inflammatory Pathway: Mechanisms and Prospects -- Chapter 5. Neurodegenerative Diseases and Small Molecule Protein Chaperone Activator of Natural Origin -- Chapter 6. Role of Phytomolecules on the Basic Biology of Aging -- Chapter 7. Role of phytomedicine in alleviating oxidative stress mediated vascular complications in diabetes -- Chapter 8. Plant Based -Secretase (BACE-1) Inhibitors: A Mechanistic Approach to Encounter Alzheimer's Disorder -- Chapter 9. Bioactive Compounds of Mangroves as Potent Drug and in Nanoparticle Synthesis - Play a Pivotal Role in Combating Human Pathogens. Chapter 10. Medicinal Plants: A Rich Source of Bioactive Molecules Used in Drug Development -- Chapter 11. Cell-based Assays in Natural Product-based Drug Discovery -- Chapter 12. Allelochemicals: An Emerging Tool for Weed Management -- Chapter 13. Secondary Metabolites of Higher Plants as Green Preservatives of Herbal Raw Materials and Their Active Principles During Postharvest Processing -- Chapter 14. Importance of Chromatography Techniques in Phytomedicine Research -- Chapter 15. Reverse Pharmacology – A Tool for Drug Discovery From Traditional Medicine -- Chapter 16. Role of Modern Biological Techniques in Evidence-Based Validation of Ayurvedic Herbometallic Preparations -- Chapter 17. HPTLC Fingerprinting analysis of Phytoconstituents from Indigenous Medicinal Plants -- Chapter 18. Climate Change,Geographical Location and Other Allied Triggering Factors Modulate the Standardization and Characterization of Traditional Medicinal Plants: AChallenges and Prospect for Phyto-Drug Development -- Chapter 19. Molecular Docking Studies of Plant-Derived Bioactive Compounds: A Comprehensive in silico Standardization Approach -- Chapter 20. Standardization and Quality Evaluation of Botanicals with Special Reference to Marker Components -- Chapter 21. Analytical Standardization of Haridra Formulation by UV-VIS Spectrophotometry and RP-HPLC -- Chapter 22. Ethnobotanical survey: the foundation to evidence based validation of medicinal plants -- Chapter 23. Phytotherapeutics: The Rising Role of Drug Transporters in Herb-Drug Interactions with Botanical Supplements -- Chapter 24. An Insight into Herb Interactions: Clinical Evidence Based Overview -- Chapter 25. Pharmacovigilance of Herbal Medicines: An Overview -- Chapter 26. Herbal Drugs: Efficacy, Toxicity and Safety Issues -- Chapter 27. Herbal Drug Patenting -- Chapter 28. Safety and Regulatory Issues on Traditional Medicine Entrusted Drug Discovery -- Chapter 29. Pharmacovigilance of Herbal Medicine: An Evolving Discipline -- Chapter 30. Toxicity Studies Related to Medicinal Plants -- Chapter 31. Herb-Drug Interactions -- Chapter 32. Plant Based Traditional Herbal Contraceptive Use in India: Safety and Regulatory Issues -- Chapter 33. Traditional Medicine Stability and Pharmacokinetic Issue -- Chapter 34. Pharmacovigilance: Methods in developing the safety and acceptability of traditional medicines -- Chapter 35. Zoopharmacognosy (Plant-Animal Interaction) -- Chapter 36. Significance of Stability and Pharmacokinetic issues in Traditional Medicine -- Chapter 37. Pharmaceutical Formulations Development Based on the Polymers Obtained from Edible Plants: An Excellent Approach for the Betterment in Health Care Services -- Chapter 38. Evaluation of bioactivity of green nanoparticles synthesized from traditionally used medicinal plants: a review -- Chapter 39. Physicochemical, Micromeritics, Biomedical and Pharmaceutical Applications of Assam Bora Rice Starch -- Chapter 40. Natural Excipients in Pharmaceutical Formulations -- Chapter 41. A Wonder Plant Withania: Pharmacological and Chemical Perspectives -- Chapter 42. Immunomodulators and Phyto Drugs -- Chapter 43. Combined Effects of Plant Extracts on Ovarian Cell Functioning -- Chapter 44. Pterocarpussantalinus: A Wonder Gift of Nature -- Chapter 45. Phytochemicals And Investigations On Traditionally Used Medicinal Mushrooms -- Chapter 46. A Review On Investigational Studies Of Marine Macroalgae Spogomorpha Indica L -- Chapter 47. Validation of Traditional Claim of Oxalis debilis Kunth., An Ethnomedicinal Plant from North-eastern Region of India -- Chapter 48. Traditional Herbal Medicine Practiced in Plateau-Fringe and Rarh Districts of West Bengal, India -- Chapter 49. Pharmacology and Mechanisms of Natural Medicine in Treatment of Type 2 Diabetes Mellitus -- Chapter 50. Indian Traditional Herbs and Alzheimer’s Disease: Integrating Ethnobotany and Phytotherapy. .
    Abstract: The demand for traditional medicines, herbal health products, herbal pharmaceuticals, nutraceuticals, food supplements and herbal cosmetics etc. is increasing globally due to the growing recognition of these products as mainly non-toxic, having lesser side effects, better compatibility with physiological flora, and availability at affordable prices. In the last century, medical science has made incredible advances all over the globe. In spite of global reorganization and a very sound history of traditional uses, the promotion of traditional medicine faces a number of challenges around the globe, primarily in developed nations. Regulation and safety is the high concern for the promotion of traditional medicine. Quality issues and quality control, pharmacogivilane, scientific investigation and validation, intellectual property rights, and biopiracy are some key issues that restrain the advancement of traditional medicine around the globe. This book contains diverse and unique chapters, explaining in detail various subsections like phytomolecule, drug discovery and modern techniques, standardization and validation of traditional medicine, and medicinal plants, safety and regulatory issue of traditional medicine, pharmaceutical excipients from nature, plants for future. The contents of the book will be useful for the academicians, researchers and people working in the area of traditional medicine. .
    Type of Medium: Online Resource
    Pages: XII, 1151 p. 378 illus., 125 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811581274
    DDC: 615
    Language: English
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  • 18
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Natural products. ; Botany. ; Ethnology. ; Pharmacology. ; Natural Products. ; Plant Science. ; Ethnography.
    Description / Table of Contents: 1. Introduction to Western Himalayas -- 2. Achillea millefolium L., Common Yarrow -- 3. Arisaema jacquemontii Blume, Jacquemont's Cobra Lily -- 4. Species of Arnebia genus found in the western Himalayas -- 5. Species of the Berberis genus found in the western Himalayas -- 6. Dactylorhiza hatagirea (D.Don) Soo – Himalayan Marsh Orchid -- 7. Fritillaria roylei Hook.f.: Himalayan Fritillary -- 8. Gentiana kurroo Royle: Himalayan Gentian -- 9. Habenaria intermedia D.Don and Habenaria edgeworthii Hook., f. ex Collett.: The Western Himalayan medicinal Plants -- 10. Humulus lupulus L.: Beer plant -- 11. Inula racemosa Hook. f. – Puskarmool: Its ethnobotanical uses, phytochemicals and pharmacological activities -- 12. Juniperus recurva Buch.-Ham. ex D.Don and Juniperus squamata D. Don: Himalayan Juniper -- 13. Lancea tibetica Hook.f. & Thomson: Ethnobotany, phytochemistry and pharmacology -- 14. Malaxis muscifera (Lindley) O. Kuntze. and Malaxis acuminata D. Don.: Jeevak -- 15. Picrorhiza kurroa Royle ex Benth.: Kutki -- 16. Species of the genus Polygonatum found in the Western Himalayas -- 17. Species of the genus Rhodiola found in the Western Himalayas -- 18. Saussurea lappa C.B. Clarke: Kushta/Kut -- 19. Saussurea lappa C.B. Clarke: Kushta/Kut -- 20. Species of the genus Selinum found in the western Himalayas -- 21. Swertia chirayita (Roxb. ex Flem.): Chirayata/Chiretta -- 22. Taxus wallichiana Zucc.: The Himalayan yew -- 23. Tribulus terrestris L.: Gokshur /Gokharu -- 24. Species the Genus Viola found in Western Himalayas.
    Abstract: This book presents a comprehensive guide to traditional immunity-boosting medicinal plants of the Himalayas, their traditional uses, phytochemistry, pharmacology, diversity, conversation, biotechnology, toxicology, as well as future prospective. All the chapters cover the latest advances in ethnobotany, phytochemistry, biochemistry, and biotechnology. The book offers a valuable asset for researchers and graduate students of chemistry, botany, biotechnology, microbiology, and the pharmaceutical sciences. The main purpose of the present book is to draw on the rich culture, folklore, and biodiversity of immunity-boosting medicinal plants of the Western Himalayas, with particular emphasis on the Indian Trans-Himalayan and Western Himalayan region. All the plants included in the present book are extensively used by the local tribes and people for their health-promoting properties from ancient times. This book will be a substantial contribution to the knowledge of the region and the country. Also, the book will be very useful to scientists, graduates, and undergraduates, along with researchers in the fields of natural products, herbal medicines, ethnobotany, pharmacology, chemistry, and biology. Further, it is an equally significant resource for a person working in different traditional medicinal systems; doctors (especially those engaged in Ayurveda, Chinese traditional medicinal system, Amchi, and allopathy); the pharmaceutical industry (for drug design and synthesis); biochemistry and biotechnology sciences; and the agricultural sciences. .
    Type of Medium: Online Resource
    Pages: XIX, 609 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811995019
    DDC: 615
    Language: English
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  • 19
    Keywords: Pharmacology. ; Pharmacy. ; Biotechnology. ; Pharmacology. ; Pharmacy. ; Biotechnology.
    Description / Table of Contents: 1 Antiviral Drugs Against Herpesviruses -- 2 An Update on Antiretroviral Therapy -- 3 Structural Insights to Human Immunodeficiency Virus (HIV-1) Targets and their Inhibition -- 4 LEDGINs, Inhibitors of the Interaction between HIV-1 Integrase and LEDGF/p75, are Potent Antivirals with a Potential to Cure HIV Infection -- 5 Moving Fast Towards Hepatitis B Virus Elimination -- 6 Discovery and Development of Antiviral Therapies for Chronic Hepatitis C Virus Infection -- 7 Phytoconstituents as Lead Compounds for Anti-dengue Drug Discovery -- 8 Anti-influenza Drug Discovery and Development: Targeting the Virus and its Host by all -- 9 Search, Identification and Design of Effective Antiviral Drugs against Pandemic Human Coronaviruses -- 10 Peptide Based Antiviral Drugs -- 11 Covalent Antiviral Agents -- 12 Safe-in-Man Broad Spectrum Antiviral Agents -- 13 Exploiting Ubiquitin ligases for Induced Target Degradation as an Antiviral Strategy. .
    Abstract: This book summarizes state-of-the-art antiviral drug design and discovery approaches starting from natural products to de novo design, and provides a timely update on recently approved antiviral drugs and compounds in advanced clinical development. Special attention is paid to viral infections with a high impact on the world population or highly relevant from the public health perspective (HIV, hepatitis C, influenza virus, etc.). In these chapters, limitations associated with adverse effects and emergence of drug resistance are discussed in detail. In addition to classical antiviral strategies, chapters will be dedicated to discuss the non-classical drug development strategies to block viral infection, for instance, allosteric inhibitors, covalent antiviral agents, or antiviral compounds targeting protein–protein interactions. Finally, current prospects for producing broad-spectrum antiviral inhibitors will be also addressed. The book is distinctive in providing the most recent update in the rapidly evolving field of antiviral therapeutics. Authoritative reviews are written by international scientists well known for their contributions in their topics of research, which makes this book suitable for researchers not only within the antiviral research community but also attractive to a broad audience in the drug discovery field. This book covers molecular structures and biochemical mechanisms mediating the antiviral effects, while discussing various ligand design strategies, which include traditional medicinal chemistry, computational chemistry, and chemical biology approaches. The book provides a comprehensive review of antiviral drug discovery and development approaches, particularly focusing on current innovations and future trends.
    Type of Medium: Online Resource
    Pages: XI, 357 p. 142 illus., 64 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811602672
    Series Statement: Advances in Experimental Medicine and Biology, 1322
    DDC: 615
    Language: English
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  • 20
    Keywords: Pharmacology. ; Food science. ; Medicinal chemistry. ; Pharmacology. ; Food Science. ; Medicinal Chemistry.
    Description / Table of Contents: 1 Zingiber officinale - Its Ethanobotanical Uses, Phytochemistry and Pharmacology -- 2 An Insight in to the Phytochemistry, Traditional uses and Pharmacology of Ziziphus spina-christi (L) Willd. (Sidr): An Edible wild plant of Arabian Peninsula -- 3 Traditional Uses, Phytochemistry and Pharmacological Profile of Salvadora persica Linn -- 4 Phytochemistry, Pharmacology and Applications of Ocimum sanctum (Tulsi) -- 5 Nigella sativa: Its Ethnobotany, Phytochemistry and Pharmacology -- 6 A Review on Ethnomedicinal, Phytochemistry and Pharmacological Activities of Rumex hastatus D. Don -- 7 Chemical Composition and Biological Uses of Crocus sativus L.(Saffron) -- 8 Positive Health Benefits of Saponins from Edible Legumes: Phytochemistry and Pharmacology -- 9 Taraxcum officinale: The Esculent Dandelion as Herbal Medicine -- 10 Arctium lappa: A Review on its Phytochemistry and Pharmacology -- 12 Cichorium intybus: A Comprehensive Review on its Pharmacological Activity and Phytochemistry -- 13 Phytochemical and Pharmacological Properties of Picrorhiza kurroa -- 14 Lady's Purse (Capsella bursa-pastoris L.)-Current perspective on its ethanopharmacological, therapeutic potential and phytochemistry -- 15 Ethnopharmaology, Phytochemistry and Biological Activities of Achillea millefolium: A Comprehensive Review -- 16 A Review on Traditional Uses, Phytochemistry and Pharmacological Activities of Verbascum thapsus -- 17 Acorus calamus - A Review on Its Phytochemical and Pharmacological Profile.
    Abstract: The book provides essential information on some of the promising edible medicinal plants and how these possess both nutritional as well as therapeutic value. The significance of the edible plants in traditional medicine and the importance of the distribution of their chemical constituents are discussed systematically concerning the role of these plants in ethnomedicine in different regions of the world. The current volume deals with the individual plants' phytochemical and pharmacological properties, emphasizing human health. The title would demonstrate the value of natural edible plants and introduce readers to state-of-the-art developments and trends in omics-driven research. This book is a single-source scientific reference to explore the specific factors that contribute to these potential health benefits and discuss how to maximize those potential benefits. Chemists, food technologists, pharmacologists, phytochemists, and all professionals involved with quality control and standardization will find in this book a valuable and updated basis for their work.
    Type of Medium: Online Resource
    Pages: IX, 522 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811649592
    DDC: 615
    Language: English
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  • 21
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Medicine Research. ; Biology Research. ; Biomaterials. ; Pharmacy. ; Biomedical engineering. ; Pharmacology. ; Biomedical Research. ; Biomaterials. ; Pharmacy. ; Translational Research. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: Chapter 1. Marine biopolymers for oral delivery of drug -- Chapter 2. Marine polymer based nanocarriers for drug delivery application -- Chapter 3. Alginate: A promising biopolymer in drug delivery system -- Chapter 4. Chitosan Based Nanocomposite as Targeted drug delivery Carrier -- Chapter 5. Marine Biopolymer Based Oral In situ Gel: Drug Delivery Applications -- Chapter 6. Marine biopolymers for transdermal drug delivery -- Chapter 7. Marine polysaccharides for skin drug delivery: hydrogels and microneedles solutions -- Chapter 8. Marine collagen: promising biomaterial in delivery of therapeutics for cancer therapy -- Chapter 9. Chitosan based gel for ocular drug delivery. Chapter 10. Marine based biopolymers for central nervous system drug delivery -- Chapter 11. Marine Biopolymers Based Anticancer Drug Delivery Systems -- Chapter 12. Marine-Derived polysaccharides: prospects for future pharmaceuticals and drug delivery systems.
    Abstract: This book is focused on marine based biomedical carriers for delivery of therapeutics. Marine biomaterials and bio-based carriers show wide applications in pharmaceutical as well as biomedical fields for delivery of small and large molecules. Biomaterial-based composites, scaffolds or matrix systems are promising systems for controlled and prolonged release of drug in target site and control the premature release of drugs or bioactive compounds. This book discusses the targeted delivery of drugs and therapeutic applications. It also describes the use of marine biopolymers in cancer therapy. Different chapters describe the tissue engineering techniques to develop these carriers. The marine biomaterial-based systems are widely used for tissue engineering, and biomedical imaging. This book is meant for industry experts, students and researchers in the area of pharmaceutical sciences, biomedical engineering and material science and pharmacology.
    Type of Medium: Online Resource
    Pages: X, 453 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811647871
    DDC: 615
    Language: English
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  • 22
    Keywords: Pharmacology. ; Natural products. ; Nanobiotechnology. ; Bioinformatics. ; Diseases Causes and theories of causation. ; Molecular biology. ; Pharmacology. ; Natural Products. ; Nanobiotechnology. ; Bioinformatics. ; Pathogenesis. ; Molecular Biology.
    Description / Table of Contents: 1. COVID-19: An overview of virology, mutations, pathology, epidemiology, diagnosis, preventions and treatments -- 2. The recent development of therapeutic strategies against COVID-19 -- 3. Plant immunoenhancers: Promising ethnopharmacological candidates for anti-SARS-CoV-2 activity -- 4. Herbal formulations in fighting against the SARS-CoV-2 infection -- 5. Rejuvenation of traditional medicine in the 21st century against SARS-CoV-2 -- 6. Traditional herbal medicines and their active constituents in combating SARS-CoV-2 infection -- 7. Antiviral phytocompounds against animal-to-human transmittable SARS-CoV-2 -- 8. Plants-derived bioactive compounds as potential ACE-2 inhibitors against SARS-CoV-2 infection -- 9. Insights into in silico methods to explore plant bioactive substances in combating SARS-CoV-2 -- 10. Dietary plants, spices and fruits in curbing SARS-CoV-2 virulence -- 11. Therapeutic potential of selected medicinal plants for neurological disorders after the infection of COVID-19 -- 12. Glycyrrhizae Radix et Rhizoma (Gan Cao) for the management of COVID-19 -- 13. COVID-19-induced kidney disease: Ethnopharmacological intervention to ameliorate kidney damage and improve kidney function -- 14. Phytochemicals and nutraceuticals targeting SARS-CoV-2: An in silico analysis -- 15. Therapeutic and prophylactic effects of plant derivatives against SARS-CoV-2 -- 16. Therapeutic potential of essential oils against SARS-CoV-2 infection -- 17. Antiviral properties of South Indian plants against SARS-CoV-2 -- 18. Immune-boosting plants used in Turkish folk medicine and their potential against COVID-19 -- 19. A comparison study of medicinal plants used against SARS-CoV-2 and those recommended against malaria in Africa -- 20. Exploring the potential antiviral properties of Nigella sativa L. against SARS-CoV-2: Mechanisms and prospects -- .
    Abstract: This book presents a complete overview of COVID-19 and provides a series of in-depth analyses of the literature and a comprehensive discussion and perspectives on promising anti-SARS-CoV-2 agents based on the system of ethnopharmacology, which covers Chinese medicine, traditional medicines of India and Africa, Turkish folk medicine, essential oils, and some well-known medicinal plants. In this book, the current status of therapeutic strategies against COVID-19 was summarized and a perspective of potential options for the future was proposed. Based on ethnopharmacology, some well-established traditional herbal formulations and bioactive compounds with anti-virus activity were repurposed for managing COVID-19 and post-illness, including neurological disorders and kidney illness. Using drug discovery tools, promising immune enhancers were explored from phytochemicals against SARS-CoV-2. Nutraceuticals from dietary plants, spices, and fruits with anti-virus and antioxidant activities were recommended to prevent infection or severe illness caused by emerging variants. With the aid of systems pharmacology, researchers have gained insights into possible molecular mechanisms of anti-SARS-CoV-2 activity and have predicted a range of candidate compounds from medicinal plants to combat COVID-19. This book explores the current knowledge of drug discovery and ethnopharmacology for managing coronavirus diseases. The content proved the anti-SARS-CoV-2 activity from natural products and traditional herbal medicines. It contributes to the management of global public health and fits the goal of establishing “Good Health and Well-Being,” which is one of “The Sustainable Development Goals (SDGs) 2030".
    Type of Medium: Online Resource
    Pages: IX, 590 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819936649
    DDC: 615
    Language: English
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  • 23
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Veterinary medicine. ; Animal biotechnology. ; Veterinary Science. ; Animal Biotechnology.
    Description / Table of Contents: Chapter 1_Introduction to sperm sexing -- Chapter 2_Semen and sperm characteristics of farm animals -- Chapter 3_Conventional methods of sperm sexing -- Chapter 4_ Sperm sexing using flow cytometry: Principles and applications -- Chapter 5_Recent advances and challenges in the development of novel sperm sexing methods -- Chapter 6_Semen extenders for preservation of sorted semen -- Chapter 7_Commercial and ethical aspects of sperm sexing.
    Abstract: This book presents basic principles and discusses the state-of-the-art methods of sperm sexing in livestock. It reviews the challenges and critical opinions on the conventional sperm sexing methods and characteristic features of spermatozoa of farm animals which could help to develop novel methods of sperm sexing. The book also presents principles and applications of flow cytometry for sperm separation. The chapters of the book elucidate methods and difficulties in developing sperm sexing methods. Notably, it covers recent research on immunological and nanotechnology-based sperm sexing methods. The book also provides information on the development of semen extenders. Towards the end, the book examines ethical and commercial aspects of sperm sexing. It is an ideal reference book for students, researchers and professionals working towards improving livestock production.
    Type of Medium: Online Resource
    Pages: XV, 112 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811917905
    DDC: 636.089
    Language: English
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  • 24
    Keywords: Pharmacology. ; Pharmacy. ; Alternative medicine. ; Pharmacovigilance. ; Medicinal chemistry. ; Pharmacology. ; Pharmacy. ; Complementary and Alternative Medicine. ; Drug Safety and Pharmacovigilance. ; Medicinal Chemistry.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Measuring Herb-drug interaction and Synergy -- Chapter 3. Herb-Herb and Food-drug interactions -- Chapter 4. Pharmacokinetic interactions in synergistic herb-drug combinations -- Chapter 5. Antagonistic Herb-drug interactions -- Chapter 6. Synergistic Herb-drug interactions against bacteria -- Chapter 7. Synergistic herb-drug interactions against tuberculosis -- Chapter 8. Synergistic herb-drug interactions against viral diseases -- Chapter 9. Synergistic herb interactions with cardiovascular drugs -- Chapter 10. Synergistic herb interactions with anticancer drugs -- Chapter 11. Synergistic herb interactions with antidiabetic drugs -- Chapter 12. Synergistic herb-drug interactions against obesity -- Chapter 13. Synergistic Herb-Drug Interactions in Neurological Disorders -- Chapter 14. Synergistic Herb-drug interactions with antifungal and antiparasitic agents -- Chapter 15. Computational methods to study herb-drug interactions -- Chapter 16. Regulations and guidelines involving synergistic plant-drug interactions -- Chapter 17. Clinical trials on synergistic herb-drug interactions -- Chapter 18. QFuture prospects on synergistic herb-drug interactions -- Chapter 19. Conclusion.
    Abstract: Plant extracts or their pure natural constituents have been used traditionally for thousands of years for treating diseases with considerable success in India and other Asian countries. In addition, they have also been used as complements or supplements with conventional medicine. This book discusses the latest research in the application of combination therapy, namely herbs and drugs, in the treatment of a range of communicable and non-communicable diseases to achieve a synergistic effect. This synergy may help in reducing the amount of drug, its toxicity, side effects, and development of resistance as well as improve its efficacy. The book also discusses the pharmacodynamic and pharmacokinetic parameters, experimental tools to determine the impact of combination, computational approaches to identify synergy, statistical analysis of data, and clinical and regulatory issues. The book is useful for researchers in the fields of pharmacology, pharmacy and medicinal chemistry and those working in pharmaceutical and nutraceutical industries. This book could open up new strategies to focus on multiple targets to combat complex diseases unlike the single targeted drugs that are being currently marketed by the pharmaceuticals industries.
    Type of Medium: Online Resource
    Pages: XV, 276 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811951251
    DDC: 615
    Language: English
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  • 25
    Keywords: Pharmacology. ; Medicine Research. ; Biology Research. ; Medical genetics. ; Pharmacology. ; Biomedical Research. ; Medical Genetics.
    Description / Table of Contents: Chapter 1. Introduction and Principles of Pharmacogenomics and Precision medicine -- Chapter 2. Pharmacogenomics in Cardiovascular Diseases -- Chapter 3. Pharmacogenomics of Antitumor Chemotherapeutic Agents -- Chapter 4. Pharmacogenomics of Antitumor Targeted Agent and Immunotherapy -- Chapter 5. Pharmacogenomics of Immunosuppressant -- Chapter 6. Pharmacogenomics of Psychiatric drugs -- Chapter 7. Pharmacogenomics of Anti-Infective Agents -- Chapter 8. Pharmacogenomics of Antithrombotic drugs -- Chapter 9. Pharmacogenomics in Therapeutic Drug Monitoring -- Chapter 10. Pharmacomicrobiomics -- Chapter 11. Genotyping technology in Pharmacogenomics -- Chapter 12. The Ethical, Legal and Regulatory Issues Associated with Pharmacogenomics -- Chapter 13. Cost-effectiveness of pharmacogenetic-guided treatment -- Chapter 14. Application of pharmacogenomics in drug discovery and development -- Chapter 15. Barriers and Solutions in Clinical Implementation of Pharmacogenomics for Personalized Precision Medicine.
    Abstract: This book provides an introduction to the principles of pharmacogenomics and precision medicine, followed by the pharmacogenomics aspects of major therapeutic areas such as cardiovascular disease, cancer, organ transplantation, psychiatry, infection, antithrombotic drugs. It also includes genotyping technology and therapeutic drug monitoring in Pharmacogenomics; ethical, Legal and Regulatory Issues; cost-effectiveness of pharmacogenetics-guided treatment; application of pharmacogenomics in drug discovery and development and clinical Implementation of Pharmacogenomics for Personalized Precision Medicine. The contributors of Pharmacogenomics in Precision Medicine come from a team of experts, including professors from academic institutions and practitioner from hospital. It will give an in-depth overview of the current state of pharmacogenomics in drug therapy for all health care professionals and graduate students in the era of precision medicine.
    Type of Medium: Online Resource
    Pages: VIII, 289 p. 33 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811538957
    DDC: 615
    Language: English
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  • 26
    Keywords: Pharmacology. ; Therapeutics. ; Internal medicine. ; Fungi. ; Mycology. ; Microbiology. ; Medical microbiology. ; Pharmacology. ; Therapeutics. ; Internal Medicine. ; Fungi. ; Medical Microbiology.
    Description / Table of Contents: Chapter 1. Mushrooms as Promising Therapeutic Resources: Review and Future Perspectives -- Chapter 2. Medicinal Mushrooms for Respiratory Health -- Chapter 3. Therapeutic and Prophylactic Potential of Medicinal Mushrooms in COVID-19 -- Chapter 4. Influences of Edible Mushrooms on Dynamic and Diversity of Gut Microbiota -- Chapter 5. Mushrooms – From Traditional Remedies to the Modern Therapeutics -- Chapter 6. Biopharmaceutical Potential of Ophiocordyceps sinensis for Human Health -- Chapter 7. Anticancer Potential of Ganoderma lucidum and İts Relevant Modes of Action -- Chapter 8. Cognitive Enhancing Effects of Medicinal Mushrooms: A Potential Neuroprotective Implication in Dementias -- Chapter 9. Potential of Medicinal Mushrooms in Human Health and Welfare: An Overview -- Chapter 10. Mycotherapeutics Reduce Nephrotoxicity and Renal Diseases -- Chapter 11. Proteomic Research on the Therapeutic Properties of Medicinal Mushrooms -- Chapter 12. Cordyceps militaris (L.): Medicinal aspects in terms of ethnobotanical and pharmacological perspectives -- Chapter 13. Mycotherapeutics Affecting Dopaminergic Neurotransmission to Exert Neuroprotection -- Chapter 14. Biological Activities of Some Edible Mushrooms -- Chapter 15. Nephroprotective Effects of Four Ganoderma Species -- Chapter 16. Mechanisms Involved in Edible Mushrooms' Health Beneficial Effects -- Chapter 17. Mycotherapy (Medicinal Mushrooms) as a Potential Treatment for Epilepsy -- Chapter 18. Natural vs. Synthetic Psilocybin: The Same or Completely Different? -- Chapter 19. Preventative and Curative Properties of Reishi and Maitake Mushrooms in Cancer.
    Abstract: The book presents new and novel perceptions about ailments alleviating the effects of several mushroom species. Also, the book highlights the curative role of medicinal mushrooms on some peripheral and central diseases. Various chapters in the book (primarily reviews) have been dedicated to providing the therapeutic efficacy of mushrooms against respiratory illnesses, gut microbiota, COVID-19, dementia, epilepsy, mental ailments, cancers, cardiovascular, kidney-related diseases, and other common pathologies. Thus, medicinal mushrooms are current and future consumable healthcare products that usually exhibit nourishing properties and possess prophylactic and therapeutic values with minimal adverse effects and contraindications. The book focuses on Sustainable Development Goal (SDG 3) to promote healthy lives and well-being for all. Medical, pharmacy, nursing, and CAM (complementary and alternative medicine) students, practitioners, scholars, researchers, other healthcare professionals, and general readers are this book’s potential audience. The book can be adopted as a textbook for undergraduate and graduate courses so that the therapeutic potential of mushrooms can reach a wider audience. This book strives to create a new resource for the future use of medicinal mushrooms in various disorders. .
    Type of Medium: Online Resource
    Pages: XX, 509 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811995507
    DDC: 615
    Language: English
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  • 27
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Gynecology . ; Environmental health. ; Pharmacology. ; Gynecology. ; Environmental Health.
    Description / Table of Contents: Preface -- Environmental Exposure Measurements and Evaluations -- Prenatal Smoke Exposure and Child Health -- Prenatal Pesticide Exposure and Child Health -- Prenatal Metal Exposure and Child Health -- Prenatal Stress and Child Health -- The Special Vulnerabilities of Child to Environmental Hazards -- Early-life Environmental Influences on Growth -- Early-life Environmental Influences on Neural Development -- Early-life Environmental Influences on Allergic Diseases -- Early-life Social and Economic Adversities on Health -- Endocrine Disrupting Chemical Exposure and Later-onset Diseases -- Paternal Specific Exposure and Child Health -- Molecular Mechanism of Early-life Chemical Exposure Induced Harmful Effects -- Transgenerational Effects on Developmental Origins of Diseases.
    Abstract: This book offers valuable insights into the latest concepts and findings from epidemiologic, clinical and basic studies in the burgeoning area of early-life environmental exposure and diseases. The book is divided into five parts, starting with an overview of environmental exposure measurement and evaluation, followed by a review of the effects of exposure to various substances like tobacco smoke, pesticides and metals as well as stress on offspring’s health. It then discusses the developmental origins of a range of childhood diseases that affect growth, neural development and the immune system, and highlights the importance of longitudinal studies that measure exposure at potentially sensitive time points during childhood. It also provides up-to-date evidence of the intergenerational/transgenerational effects of early-life environmental exposure, especially via genetic and epigenetic pathways. Allowing readers to gain a thorough understanding of the predominating aspects of early-life environmental exposure and diseases, the book also provides a basis for developing environmental and health policies that could have wide and long-term impacts on human health. .
    Type of Medium: Online Resource
    Pages: XVI, 239 p. 22 illus., 17 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811537974
    DDC: 615
    Language: English
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  • 28
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Clinical biochemistry. ; Medicinal chemistry. ; Pharmacy. ; Pharmacology. ; Medical Biochemistry. ; Medicinal Chemistry. ; Pharmacy.
    Description / Table of Contents: Chapter 1. Coleus forskohlii – A multipurpose medicinal plant -- Chapter 2. Botany of Coleus forskohlii -- Chapter 3. Traditional Medicinal Uses and Pharmacognosy of Coleus forskohlii -- Chapter 4. Chemistry of Coleus forskohlii Briq. -- Chapter 5. Pharmacology of Coleus forskohlii and Forskolin -- Chapter 6. Micropropagation of Coleus forskohlii -- Chapter 7. In Vitro Production of Forskolin -- Chapter 8. Assessment of Coleus forskohlii Genetic Diversity Using Molecular Markers -- Chapter 9. Endophytes for the enhanced growth of Coleus forskohlii and enhanced production of Forskolin -- Chapter 10. Propagation Methods of Coleus forskohlii -- Chapter 11. Success stories and Trade and Commerce of Coleus forskohlii.
    Abstract: This monograph compiles updated information about forskolin, a labdane diterpene that is produced by the Coleus plant. Forskolin has a large number of practical uses and the book delves into the various aspects of this chemical. It includes topics such as the botanical source of forskolin and the cultivation of Coleus forskohlii, source. It also covers the biosynthetic pathways in natural sources and also through different biotechnological applications. Chapters include the potential and products in the Forskolin market. The book also covers the methods for enhanced production of forskolin from natural sources and through tissue culture methods for improvement of the plant for higher content of forskolin. It discusses the role of endophytes in the production of forskolin. The book is useful for students and researchers in the field of botany, pharmacology and biochemistry. It also serves scientists in various pharmaceutical industries.
    Type of Medium: Online Resource
    Pages: XI, 177 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811965210
    DDC: 615
    Language: English
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  • 29
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Medicinal chemistry. ; Polymers. ; Biotechnology. ; Pharmacology. ; Medicinal Chemistry. ; Polymers. ; Biotechnology.
    Description / Table of Contents: Chapter 1. Interpenetrating Polymer Network in Microparticulate Systems: Drug Delivery and Biomedical Application -- Chapter 2. Interpenetrating Polymer Network (IPN) Nanoparticles for Drug Delivery Applications -- Chapter 3. Fabrication Technology of Chitosan-Based IPN: Drug Delivery Application -- Chapter 4. Alginate based Interpenetrating Network Carriers for Biomedical Applications -- Chapter 5. pH Sensed Interpenetrating Polymeric Network: Application in drug delivery -- Chapter 6. IPN Dendrimers in Drug Delivery -- Chapter 7. BioproteinBased IPN Nanoparticles as Potential Vehicles for Anticancer Drug Delivery: Fabrication Technology -- Chapter 8. Semi-IPN systems for drug delivery -- Chapter 9. IPN Systems for Cancer Therapy -- Chapter 10. Semi-interpenetrating networks based on (meth)acrylate, itaconic acid and poly(vinyl pyrrolidone) hydrogels for biomedical applications -- Chapter 11. Biomedical Applications of Interpenetrating Polymer Network Gels -- Chapter 12. Bio-Nanocomposite IPN for Biomedical Application.-.
    Abstract: The book focuses on novel interpenetrating polymer network (IPN)/semi-IPN technologies for drug delivery and biomedical applications. The dynamism of the design and development of interpenetrating network polymers is based on their ability to provide free volume for the easy encapsulation of drugs in the three-dimensional network structure obtained by cross-linking two or more polymer networks. Natural polymer-based IPNs can deliver drugs at a controlled rate over an extended period of time, while novel IPNs ensure better mechanical strength and sustained/ controlled drug-delivery properties. This book presents an overview of the use of this technology to fabricate nanomedicine, hydrogels, nanoparticles, and microparticles, thereby unlocking IPN’s potential in the area of drug delivery and biomedical engineering. It also discusses applications of IPN systems in cancer therapy and tissue engineering, and describes the various IPN systems and their wide usage and applications in drug delivery.
    Type of Medium: Online Resource
    Pages: XII, 337 p. 59 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811502835
    DDC: 615
    Language: English
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  • 30
    Keywords: Pharmacology. ; Human physiology. ; Nanotechnology. ; Biology Technique. ; Pharmacology. ; Human Physiology. ; Nanotechnology. ; Experimental Organisms.
    Description / Table of Contents: Chapter 1. Nanotechnology : Application in biology and medicine -- Chapter 2. Biological activities of nanoparticles and mechanism of action -- Chapter 3. Application of nanoparticles in Drug delivery -- Chapter 4. Antimicrobial activity of metallic nanoparticles using prokaryotic model organisms -- Chapter 5. Modelling nanoparticles parameters for antibacterial activities -- Chapter 6. Saccharomyces cerevisiae as model organism to study biological activities of nanoparticles -- Chapter 7. Investigation of Biological activities of Nanoparticles using Cell Lines -- Chapter 8. Caenorhabditis elegans: a model organism to decipher biological activities of nanoparticles -- Chapter 9. Zebra fish model system to investigate biological activities of nanoparticles -- Chapter 10. Drosophila melanogaster - A model organism to understand biological activities of nanoparticles -- Chapter 11. Understanding the biological activities of nanoparticles using murine models -- Chapter 12. Insecticidal activity nanoparticles and mechanism of action -- Chapter 13. Routes of Exposures and Toxicity of Nanoparticles -- Chapter 14. Toxicological evaluation of nanoparticles using prokaryotic model organisms -- Chapter 15. Evaluation of Toxicity Nanoparticles using Cell lines -- Chapter 16. Saccharomyces cerevisiae : Model organism to evaluate nanoparticles toxicity -- Chapter 17. Caenorhabditis elegans: Evaluation of nanoparticle toxicity -- Chapter 18. Zebra fish: A laboratory model to evaluate Nanoparticle Toxicity -- Chapter 19. Evaluation of toxicity of nanoparticles using Brine Shrimp -- Chapter 20. Drosophila Model to Decipher the Toxicity of Nanoparticles -- Chapter 21. Murine models to understand the toxicity of nanoparticles -- Chapter 22. Challenges and future perspectives of Nanotoxicology.
    Abstract: This book provides a comprehensive overview of state-of-the-art applications of nanotechnology in biology and medicine, as well as model organisms that can help us understand the biological activity and associated toxicity of nanoparticles, and devise strategies to minimize toxicity and enhance therapies. Thanks to their high surface-to-volume ratio, nanoparticles are characterized by excellent biocompatibility and bioavailability, a high therapeutic index, and relatively low toxicity, which has led to their widespread application in the early diagnosis of diseases, comprehensive monitoring of disease progression, and improved therapeutics. The book also explores nanoparticle-based insecticides and their mechanisms of action, and provides a comparative analysis of the various model organisms that are used to understand the biological properties of nanoparticles. Further, it describes various in-vivo models that yield important insights into nanomaterial-mediated toxicity, promoting the optimal utilization of nanoparticles. In closing, the book discusses future perspectives and regulatory issues concerning the use of nanomaterials in translational research.
    Type of Medium: Online Resource
    Pages: XIII, 466 p. 64 illus., 55 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811517020
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Bioinformatics. ; Proteins. ; Pharmacology. ; Computational and Systems Biology. ; Proteins.
    Description / Table of Contents: 1 Computational Approaches in Drug Discovery and Design -- 2 Molecular Modeling of Proteins: Methods, Recent Advances and Future Prospects -- 3 Cavity/Binding Site Prediction Approaches, and their Applications -- 4 Role of ADMET Tools in Current Scenario; Application and Limitations -- 5 Database Resources for Drug Discovery -- 6 Molecular Docking and Structure-Based Drug Design -- 7 Molecular Dynamics Simulation of Protein and Protein-Ligand Complexes -- 8 Computational Approaches for Drug Target Identification -- 9 Computational Screening Techniques for Lead Design and Development -- 10 Advances in Pharmacophore Modeling and its Role in Drug Designing -- 11 In Silico Designing of Vaccines: Methods, Tools and Their Limitations -- 12 Machine learning Approaches to Rational Drug Design. .
    Abstract: This book provides up-to-date information on bioinformatics tools for the discovery and development of new drug molecules. It discusses a range of computational applications, including three-dimensional modeling of protein structures, protein-ligand docking, and molecular dynamics simulation of protein-ligand complexes for identifying desirable drug candidates. It also explores computational approaches for identifying potential drug targets and for pharmacophore modeling. Moreover, it presents structure- and ligand-based drug design tools to optimize known drugs and guide the design of new molecules. The book also describes methods for identifying small-molecule binding pockets in proteins, and summarizes the databases used to explore the essential properties of drugs, drug-like small molecules and their targets. In addition, the book highlights various tools to predict the absorption, distribution, metabolism, excretion (ADME) and toxicity (T) of potential drug candidates. Lastly, it reviews in silico tools that can facilitate vaccine design and discusses their limitations.
    Type of Medium: Online Resource
    Pages: XIII, 306 p. 80 illus., 54 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811568152
    DDC: 615
    Language: English
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  • 32
    Keywords: Veterinary medicine. ; Physiology. ; Cardiovascular system. ; Reproduction. ; Veterinary Science. ; Animal Physiology. ; Cardiovascular Physiology. ; Reproductive Physiology.
    Description / Table of Contents: Section 1: Introduction -- Chapter 1.1. Veterinary physiology - past, present and future perspective -- Chapter 1.2. Cellular and molecular physiology -- Chapter 1.3. Action potential -- Section 2: Hematology and Immune System -- Chapter 2.1. Hematology -- Chapter 2.2. Immune system -- Section 3: Cardiovascular, Respiratory and Excretory System -- Chapter 3.1. Cardiovascular system -- Chapter 3.2. Physiology of respiration -- Chapter 3.3. Fluid and electrolyte balance -- Chapter 3.4. Excretory physiology -- Section 4: Neuro-muscular System and Special Senses -- Chapter 4.1. Muscular system -- Chapter 4.2. Nervous system -- Chapter 4.3. Special senses -- Section 5: Digestive System -- Chapter 5.1. Physiology of digestion -- Chapter 5.2. Ruminant digestion -- Section 6: Endocrine System -- Chapter 6.1. General endocrinology and hormones of hypothalamus and pituitary -- Chapter 6.2. Hormonal regulation of metabolism, water, and minerals -- Chapter 6.3. Hormones of gonads and non-classical endocrine organs -- Section 7: Reproductive System -- Chapter 7.1. Development of sex organs -- Chapter 7.2. Functional morphology of the male reproductive system -- Chapter 7.3. Spermatogenesis and Semen -- Chapter 7.4. Functional morphology of the female reproductive system -- Chapter 7.5. Female reproductive physiology -- Chapter 7.6. Fertilisation, gestation and parturition -- Chapter 7.7. Assisted reproductive technologies in farm animals -- Section 8: Lactation Physiology -- Chapter 8. Lactation physiology -- Section 9: Physiology of Growth and Behaviour -- Chapter 9.1. Physiology of growth -- Chapter 9.2. Physiology of animal behaviour -- Section 10: Environment and Thermoregulation -- Chapter 10.1. Environmental physiology and thermoregulation in farm animals -- Chapter 10.2. Thermoregulation in birds.
    Abstract: This textbook explores the fundamental qualitative and quantitative aspects of veterinary physiology. It presents the morphological description of the organs, tissues, and cells involved in the physiological system with species variation. The book provide the most up-to-date information and in depth knowledge in animal physiology. The book addresses a broad range of topics, including the physiology of digestion in, monogastric animals, ruminants, and birds, and cardio vascular and respiratory system in different animals. The chapters contain a wealth of information on the areas related to the endocrine system, excretory system, body fluid homeostasis, hematology, male and female reproductive systems, coordination of body functions, and regulation of brain functions and sense organs. Further, this book acquaints students with advanced topics like immune system, assisted reproductive technology, ovarian dynamics, environmental physiology and thermoregulation, and behavioral physiology. This textbook contains clear illustrations including graphical abstracts and study questions for each chaptermaking this book a valuable learning resource for veterinary sciences and veterinary medicine students.Further to attract students and create interest in them, interesting facts related to animal physiology have also been highlighted in form of “Know more widges”.
    Type of Medium: Online Resource
    Pages: XXIII, 803 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811994104
    DDC: 636.089
    Language: English
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  • 33
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Veterinary medicine. ; Biotechnology. ; Food science. ; Nutrition   . ; Veterinary Science. ; Biotechnology. ; Food Science. ; Nutrition.
    Description / Table of Contents: Chapter 1. Brief History of Animal Nutrition -- Chapter 2. Relationship of Soil, Water, Air, Solar Energy, Plant and Animals -- Chapter 3. Chemicals of Life and Chemical Reactions in the Animal Cells -- Chapter 4. Partitioning of Foods -- Chapter 5. Water -- Chapter 6. Carbohydrates -- Chapter 7. Proteins and Other Nitrogenous Substances of Nutritional Significance -- Chapter 8. Lipids -- Chapter 9. Mineral Nutrition -- Chapter 10. Vitamins -- Chapter 11. Enzymes -- Chapter 12. Hormones in Nutrition -- Chapter 13. Use of Feed Additives on Livestock Production -- Chapter 14. Digestion, Absorption and Metabolism of Nutrients -- Chapter 15. Feeding Processes -- Chapter 16. Energy Partitioning -- Chapter 17. Clinical and Therapeutic Nutrition.-.
    Abstract: The book provides comprehensive information about the different aspects of veterinary nutrition in tropical countries.The introductory chapter discuss the importance of nutrition, feeds and feeding of balanced and optimum feeds specifically required for the sustenance of life .The second chapter, discusses briefly the history of research in animal nutrition.The book further talks about the relationship between the environment and nutrition in animals; the chemical composition of plants and animals; and the various sources of feed for animals. It provides details on the different phases of life cycle in animals, and the effect of nutrition on the performance. Various Nutrients and its importance in livestock nutritionand production has been illustrated in details. Various nutrients such as water, carbohydrate, protein, fats, vitamins, minerals etc are individually dealt in a separate chapter. The digestive system,digestion and metabolism of carbohydrates, protein and fats in ruminant and non ruminant livestock have been illustrated. A dedicated chapter fully describes the activity of enzymes which are directly involved in nutrition. Also this book deals with the harmful components of animal feed which are found mainly in the unconventional feeds. The books also provide chapters like partitioning of feed& energy and also the therapeutic and clinical nutrition which are very importantfor the under graduate & post graduate students and researchers of animal nutrition and livestock production and management. This book is useful for researchers, undergraduate and post graduate students studying veterinary sciences, animal husbandry, zoology and biochemistry.
    Type of Medium: Online Resource
    Pages: XIX, 269 p. 87 illus., 14 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811591259
    DDC: 636.089
    Language: English
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  • 34
    Keywords: Pharmacology. ; Clinical biochemistry. ; Pharmacy. ; Biotechnology. ; Metabolism, Secondary. ; Plants. ; Pharmacology. ; Medical Biochemistry. ; Pharmacy. ; Biotechnology. ; Plant Secondary Metabolism.
    Description / Table of Contents: 1 In vitro approach and quantification of ‘puerarin and genistein’ - Valuable antidiabetic compounds from Pueraria tuberosa -- 2 In Vitro Exploitation of Medicinal Plants for Continuous Supply of Antidiabetic Bioactive Compounds -- 3 Lower plants as potential source of antidiabetic compounds: The present knowledge and future prospects -- 4 Tissue culture mediated biotechnological intervention in Centella asiatica: A potential antidiabetic plant -- 5 In Vitro Approaches for Mass-Propagation of Stevia rebaudiana -- 6 Swertia chirayita, an endangered anti-diabetic plant: trends in biotechnological interventions -- 7 In vitro propagation and biotechnological improvement strategies of plants with high-intensity sweetener and anti-diabetic activities -- 8 In Vitro Culture Techniques and Metabolite Engineering for Enhanced Anti-Diabetic Secondary Metabolite Production -- 9 Saffron: A prized herb with therapeutic potential against diabetes -- 10 New Insights to Enhance the Desired Anti-Diabetic Compounds in Medicinal and Aromatic Plants Exposed to Abiotic Stress Factors -- 11 Boosting of bioactive secondary metabolites in antidiabetic plants through elicitation: A simple technology for better future -- 12 Rhizobium rhizogenes mediated genetic transformation of antidiabetic plants -- 13 Production of anti-diabetic lignans in flax cell cultures -- 14 Artificial seed development of selected anti-diabetic plants, their storage and regeneration: Progress and prospect -- 15 Cryopreservation of Anti-diabetic plants. .
    Abstract: This book is a unique overview of insights on the genetic basis of anti-diabetic activity, chemistry, physiology, biotechnology, mode-of-action, as well as cellular mechanisms of anti-diabetic secondary metabolites from medicinal plants. The World Health Organization estimated that 80% of the populations of developing countries rely on traditional medicines, mostly plant drugs, for their primary health care needs. There is an increasing demand for medicinal plants having anti-diabetic potential in both developing and developed countries. The expanding trade in medicinal plants has serious implications on the survival of several plant species, with many under threat to become extinct. This book describes various approaches to conserve these genetic resources. It discusses the whole spectrum of biotechnological tools from micro-propagation for large-scale multiplication, cell-culture techniques to the biosynthesis and enhancement of pharmaceutical compounds in the plants. It also discusses the genetic transformation as well as short- to long-term conservation of plant genetic resources via synthetic seed production and cryopreservation, respectively. The book is enriched with expert contributions from across the globe. This reference book is useful for researchers in the pharmaceutical and biotechnological industries, medicinal chemists, biochemists, botanists, molecular biologists, academicians, students as well as diabetic patients, traditional medicine practitioners, scientists in medicinal and aromatic plants, Ayurveda, Siddha, Unani and other traditional medical practitioners.
    Type of Medium: Online Resource
    Pages: XVI, 469 p. 70 illus., 60 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811635298
    DDC: 615
    Language: English
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    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Drug delivery systems. ; Pharmacology. ; Pharmaceutics. ; Drug Delivery.
    Description / Table of Contents: 1. Synthesis, self-assembly and functional chemistry of Amphiphilic block copolymers -- 2. Advances in polymer optimisation for enhanced drug delivery -- 3. Dynamics of Micelle Formation -- 4. Types of Polymeric Micelles for Controlled Drug Release -- 5. Drug Solubilization and Drug Release from Polymeric Micelles -- 6. Physical and Analytical Techniques used for the Characterization of Polymeric Micelles -- 7.Stimuli-sensitive polymeric micelles for biomedical applications -- 8.Nucleic acid-based micellar therapy for the treatment of different diseases -- 9. Polymeric micelles in the delivery of therapeutic phytoconstituents -- 10. Diagnostic applications of surface-engineered polymeric micelles -- 11. Ligand conjugated polymeric micelles for targeted delivery of drug payloads in cancer therapy -- 12. Polymeric Micelles in the Delivery of Proteins -- 13. Regulatory aspects for polymeric micelles -- 14. Toxicological and regulatory challenges in design and development of polymeric micelles -- 15. Stability of polymeric micelles and their regulatory status.
    Abstract: This book thoroughly reviews the advancements in design and applications of Polymeric Micelles (PMs) in drug delivery. It provides information on the synthesis of amphiphilic block copolymers and their types, functional chemistry for targeting and sensing, and biomedical applications. The book further provides the possibilities for designing PMs in a range of drug delivery approaches. The book addresses the molecular parameters of amphiphilic block copolymers that are required for functionalizing PMs for drug delivery applications. Additionally, the book presents recent advances in applications of PMs such as co-delivery, sensing, theranostics, delivery of nucleic acids, and proteins. Towards the end, it discusses different physico-chemical strategies to enhance the stability and drug retention of polymeric micelles and reviews the preclinical and clinical toxicity and immunogenicity-related aspects of polymeric micelles. This book is an invaluable source for academics, research, and industry professionals working in the field of polymeric micelles and drug delivery.
    Type of Medium: Online Resource
    Pages: XV, 294 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819903610
    DDC: 615
    Language: English
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  • 36
    Keywords: Pharmacology. ; Food science. ; Medicinal chemistry. ; Pharmacology. ; Food Science. ; Medicinal Chemistry.
    Description / Table of Contents: Chapter 1. The Folklore Uses and Economic Importance of Some Selected Edible Medicinal, Plants Native to Oman. A Brief Review -- Chapter 2. Socio-economic Importance of Some Promising Edible Medicinal Plants from (Rajasthan) India -- Chapter 3. Traditional and Economic Valuation of Edible Plants Used for Treatment of Diabetes -- Chapter 4. Cultural and Socio-economic Perspective of Some Promising Edible Plants from Northern Pakistan -- Chapter 5. Medicinal Plants and their Contribution In Socio-Economic Upliftment of the Household in Gurez Valley (J&K) -- Chapter 6. Comprehensive overview of Some Edible Medicinal Plants from Kashmir Valley – Cultural, Economic and Pharmacological Importance -- Chapter 7. High Altitude Edible Plants: A Great Resource for Human Health and their Socio-economic Significance -- Chapter 8. Cultural, Practical and Socio-economic Importance of Edible Medicinal Plants Native to Central India -- Chapter 9. Cultural and Scio-economic Perspective of Some Promising Edible Plants from Uttarakhand Himalaya. Chapter 10. Edible Medicinal Plants from Chhattisgarh (India) and their Economic Significance -- Chapter 11. Ethno-botanical and Economic Significance of Edible Plants Used as Food by Tribal Community of the Western Himalaya -- Chapter 12. Cultural, Practical and Economic Value of Edible Plants used by Mizo Tribes of Mizoram -- Chapter 13. Isoflavones of Soy: Chemistry and Health Benefits -- Chapter 14. Account of Some Important Edible Medicinal Plants and their Socio-Economic Importance -- Chapter 15. Cultural, Practical and Economic Significance of Some Edible Medicinal Plants from Gilgit-Baltistan Pakistan.
    Abstract: The book provides significant information on some of the promising edible medicinal plants and how these possess both nutritive as well as medicinal value. The significance of these edible plants in traditional medicine, their distribution in different regions and the importance of their chemical constituents are discussed systematically concerning the role of these plants in ethnomedicine in different regions of the world. The current volume focuses on the economic and culturally important medicinal uses of edible plants and a detailed survey of the literature on scientific researches of pharmacognostical characteristics, traditional uses, scientific validation, and phytochemical composition, and pharmacological activities. This book is a single-source scientific reference to explore the specific factors that contribute to these potential health benefits, as well as discussing how to maximize those potential benefits. Chemists, food technologists, pharmacologists, phytochemists as well as all professionals involved with quality control and standardization will find in this book a valuable and updated basis for their work.
    Type of Medium: Online Resource
    Pages: XI, 388 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811648809
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Medicine Research. ; Biology Research. ; Therapeutics. ; Pharmaceutical chemistry. ; Biomaterials. ; Pharmacology. ; Translational Research. ; Therapeutics. ; Pharmaceutics. ; Biomaterials.
    Description / Table of Contents: Chapter 1. Marine biomaterials: resources, categories and applications -- Chapter 2. Cross-linked marine biopolymers for delivery of therapeutics -- Chapter 3. Chitosan and Chitooligosaccharides: Preparation, Characteristics and their Potential Application as Therapeutic Agents -- Chapter 4. Marine collagen for delivery of therapeutics -- Chapter 5. Marine Biopolymers for delivery of Gene -- Chapter 6. Hydrogel scaffolds based on alginate, gelatin, and 2-hydroxyethyl methacrylate for tissue regeneration -- Chapter 7. Tissue Engineering application of marine based materials -- Chapter 8. Marine biopolymer for theranostic applications -- Chapter 9. Marine biomaterials as carrier of drugs/biomolecules for management of bone disorders -- Chapter 10. Expanding Role of Marine Natural Compounds in Immunomodulation: Challenges and Future Perspectives -- Chapter 11. Marine origin Bioactive Peptides: novel advances in the therapeutic potential.
    Abstract: This book provides updated information on marine-based biomedical carriers and their therapeutic potential. Marine biomaterials and bio-based carriers show wide application in pharmaceutical and biomedical fields to deliver small and large molecules. Biomaterial-based composites, scaffolds, or matrix systems are sound systems for controlled and prolonged drug release in target sites and control the premature release of drugs or bioactive compounds. This book discusses essential topics such as the therapeutic potential of marine collagen, management of bone disorders, gene delivery, natural marine compounds in immunomodulation, theranostic applications, tissue engineering, and regeneration. It also describes the use of marine biopolymers in cancer therapy. Different chapters describe the tissue engineering techniques to develop these carriers. Marine biomaterial-based systems are popular for tissue engineering and biomedical imaging. This book is ideal for industry experts, students, and researchers in pharmaceutical sciences and pharmacology.
    Type of Medium: Online Resource
    Pages: X, 392 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811653742
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Medical sciences. ; Drug development. ; Biologicals. ; Biopharmaceutics. ; Pharmacology. ; Preclinical Research. ; Biologics.
    Description / Table of Contents: Chapter 1_Introduction -- Chapter2_Systematic literature review (SLR) -- Chapter 3_Registration and software’s -- Chapter 4_Quality Assessment of Studies -- Chapter 5_Extraction and Analysis of data -- Chapter 6_Models in Meta-analysis -- Chapter 7_Heterogeneity and Publications bias -- Chapter 8_Sensitivity and subgroup analysis -- Chapter 9_Meta-regression -- Chapter 10_Plots in Meta-analysis -- Chapter 11_Network Meta-analysis -- Chapter 12_Common mistakes -- Chapter 13_Challenges -- Chapter 14_Future Perspectives -- Chapter 15_Future perspectives.
    Abstract: This book provides conceptual information on the various processes involved in meta-analysis. It examines the importance of meta-analysis for the analyses of clinical data to draw a valid conclusion using suitable software. The initial sections of the book introduce meta-analysis, how to perform a systematic literature review (SLR), quality assessment of studies, extraction, and analysis of data. The subsequent section of the book contains information on advanced topics including, meta-regression, network meta-analysis, issues, mistakes, and future perspectives. In summary, the book provides a statistical method for combining the results of different studies on the same topic and resolving conflicts among studies. This book is written with the intent to allow a wide range of readers including students, researchers, and health care professionals, including physicians, nurses, pharmacists, and paramedical, and is also helpful for a beginner who would like to do a meta-analysis.
    Type of Medium: Online Resource
    Pages: XXII, 119 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819923700
    DDC: 615
    Language: English
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    Keywords: Pharmacology. ; Medical care. ; Therapeutics. ; Neurology . ; Medicine Research. ; Biology Research. ; Pharmacology. ; Health Care. ; Therapeutics. ; Neurology. ; Biomedical Research.
    Description / Table of Contents: Chapter 1. A Complete Patent Analysis of Cannabis/Marijuana in Drug Delivery and Disease Conditions -- Chapter 2. Neuropharmacological Approaches to Modulate Cannabinoid Neurotransmission -- Chapter 3. Cannabinoids in Cancer: Cross-talk Between Cannabinoids and miRNAs -- Chapter 4. Cannabis As A Potent Therapeutic Agent For Pharmaceutical Drugs: Recent Advancement In Drug Discovery And Human Healthcare -- Chapter 5. Cannabinoid-Based Innovative Prophylactic and Therapeutic Interventions for Neuropathic Pain and Migraine -- Chapter 6. The Legality of Use and Consumption of Cannabis (Marijuana) in the United States of America -- Chapter 7. Cannabis in Healthcare: Ethnobotanical and Pharmaceutical Perspectives and Legal Status in Turkey and The Middle East -- Chapter 8. Understanding the Pharmacokinetics, Safety Profile, and Scope of the Concerned Issue to Evade the Consumption of Cannabis/Marijuana -- Chapter 9. Traditional Uses of Cannabis in The Middle East and The Pathway to Cannabis-Based Healthcare in Israel -- Chapter 10. Traditional and Modern Health Uses of Cannabis sativa L. in Africa and its Phytochemical and Pharmacological Profile -- Chapter 11. Traditional Claims on Cannabis: An Indian and Global Scenario -- Chapter 12. Cannabis (Bhanga) in Classical Text of Ayurveda: An Evidence-Based Rationale -- Chapter 13. Cannabis-Based Cosmetic Products and Their Uses -- Chapter 14. Cannabis as A Unique and Valuable Nutraceutical Formulation for the Current and Future Global Wellbeing -- Chapter 15. Traditional, Cultural, and Nutraceutical Aspects of Cannabis in India.
    Abstract: The book contains review articles providing a comprehensive overview of cannabis/marijuana’s diverse healing aspects in human healthcare (medicinal, nutraceutical, skincare, etc.). The research articles include the role of cannabis in cancer treatment, drug discovery, cosmeceutical potential, prophylactic and therapeutic use for treating neuropathic pain and migraine, pharmacokinetics, safety profile, and issues related to the consumption of cannabis/marijuana.Another salient feature of the book is a complete mapping and region- and sector-wise critical analysis of cannabis/marijuana patents on healthcare and future directions for the benefit of researchers and businesses/entrepreneurs interested in the rapidly advancing area of cannabis. The text describes cannabis/marijuana’s detailed legal aspects, production prospects, and applications for healthcare and recreational purposes in the USA. It traces the traditional roots of cannabis use in Turkey, Israel, the Middle East, Africa, and India. This unique compendium of articles will be useful as a reference book for students, researchers, academics, business houses, and all individuals interested in medicinal, nutraceutical, cosmeceutical, traditional, legal, and commercial aspects of cannabis usage.
    Type of Medium: Online Resource
    Pages: XIX, 319 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811688225
    DDC: 615
    Language: English
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    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Medicinal chemistry. ; Pharmacology. ; Pharmaceutics. ; Medicinal Chemistry.
    Description / Table of Contents: Chapter 1: Radiation biology: historical background, sources and complications -- Chapter 2: Algal radioprotective phytochemicals: Sources and potential applications -- Chapter 3: Bio-prospecting of photoprotective compounds in algae -- Chapter 4: Unraveling fungal radioprotectants and their applications -- Chapter 5: Recent advances in metabolomics and molecular genomics for the production of photoprotective compounds -- Chapter 6: Bioprospecting and evolutionary significance of radioprotectors in non-flowering lower plants -- Chapter 7: Radioprotective phytochemicals: diversity, efficacy, application and commercialization -- Chapter 8: Impacts of climate alterations in the biosynthesis of defensive natural products -- Chapter 9: Cancer therapeutics: mechanism of action, radiation toxicity and drug formulation -- Chapter 10: Role of nanotechnology in the development of radioprotective formulations -- Chapter 11: Radioprotective effects of nutraceuticals and food products -- Chapter 12: Bioprospecting of radioprotective compounds in bacterial community -- Chapter 13: Pharmacology of synthetic and natural radioprotactants: application and consequences in cancer therapeutics -- Chapter 14: Immunochemistry: consequences and mechanism of protection in chemotherapeutics -- Chapter 15: Radioprootective therapeutics: recent trends and future applications.
    Abstract: This book illustrates the role of photoprotective and radioprotective metabolites from natural sources. Various classes of radioprotective metabolites derived from cyanobacteria, algae, fungi, bryophytes, pteridophytes, gymnosperms, and higher plants have been explained to reinforce the current knowledge in this field. In addition, the book elucidates the potential applications of these metabolites in pharmaceutics, cosmetics, and biomedical sciences that will help develop commercial products in modern anti-radiation therapeutics. Topics such as stress tolerance environmental strategies, evolutionary tendency, and biosynthetic route of radioprotective compounds for cost-effective large-scale industrial production of the metabolites are also covered in the book. This book will add to the understanding of radioprotective mechanisms and curative measures for various deleterious diseases leading to cancer development. This volume also offers the latest insights into current and upcoming issues that arise from solar and atomic radiations and their amelioration by inherent radioprotective mechanisms of green plants. This book benefits readers from academia, industry, colleges, and research students to better understand the impacts of various radiations and the development of radioprotective green compounds.
    Type of Medium: Online Resource
    Pages: XIII, 264 p. 62 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819907496
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Veterinary medicine. ; Veterinary microbiology. ; Zoology. ; Veterinary Science. ; Veterinary Microbiology. ; Zoology.
    Description / Table of Contents: PART I.Microbiome of Finfish -- Chapter 1_ Introduction to fish microbiome and its importance -- Chapter 2_Isolation and Identification of Fish Gut Microbiome -- Chapter 3_ Gut Microbiome and Fish Health: An overview in Finfish Aquaculture Prospective -- Chapter 4_Fish microbiome and metagenomics -- Chapter 5_Fish and Shellfish microbiome and bioinformatics Skills -- Chapter 6_Microbiome applications for the growth and development of the aquaculture/biopharma industry.-PART II.Microbiome of Shellfish -- Chapter 7_Shellfish Microbiome -- Chapter 8_Shellfish microbiome and its significant role in immune response and health management -- Chapter 9_Microbiome and shrimp health -- Chapter 10_Microbial Metagenomics and the Shellfish Microbiome -- Chapter 11_Shellfish microbiome and Probiotics: A Decade in Review -- Chapter 12_Impact of climate change on the gut microbiome of fish and shellfish. .
    Abstract: This book helps us to understand the importance of the microbiome associated with finfish and shellfish inhabiting different locations and varied environmental and biological situations. It covers modern molecular tools for identifying microbiome composition and their precise identification at the species level. The book also covers the molecular structural composition of individual microbes, metabolite resources from microbiome species, their functional properties, and production aspects. Notable, the book covers the microbiome applications in the gut systems of finfish and shellfish to the digestion, nutrition, growth, reproduction, immune system, and vulnerability of the host to diseases. It also reviews diversity and functional properties, relationships with diseases, health status, data on species-specific metagenomics, and probiotic research. It highlights the relevance of microbial communities for the development of new and innovative bio-products to build bio and pharmaceutical industries, including aquaculture. This book is an invaluable source for researchers and professionals involved in fishery science, fisheries and aquaculture, fish biotechnology, and fish microbiology and pathology .
    Type of Medium: Online Resource
    Pages: XV, 294 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819908523
    DDC: 636.089
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Pharmacy. ; Medical sciences. ; Drug development. ; Pharmacology. ; Pharmacy. ; Preclinical Research.
    Description / Table of Contents: Chapter 1. Introduction to mammalian circadian clock system -- Chapter 2. Introduction to pharmacokinetics -- Chapter 3. Circadian clock and metabolic diseases -- Chapter 4. Circadian clock and CYP metabolism -- Chapter 5. Circadian clock and non-CYP phase I metabolism -- Chapter 6. Circadian clock and phase II metabolism -- Chapter 7. Circadian clock and uptake transporters -- Chapter 8. Circadian clock and efflux transporters -- Chapter 9. Role of pharmacokinetics in chronotherapeutics -- Chapter 10. Role of non-pharmacokinetic factors in chronoefficacy.
    Abstract: This book summarizes the recent advances for the understanding of circadian clock system in the regulation of drug metabolism and pharmacokinetics. Basic knowledge in the field of circadian clock and pharmacokinetics are systemically introduced to make it easier for readers to understand the entire book's contents. The rhythmic expression of DMEs (drug-metabolizing enzymes) and transporters are summarized, and the underlying mechanisms thereof (i.e., regulation by circadian oscillators) are discussed. Typically, evidence for the DME- and transporter-mediated chronopharmacokinetics, chronotoxicity and chronoefficacy are highlighted in this book.
    Type of Medium: Online Resource
    Pages: VII, 253 p. 59 illus., 46 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811588075
    DDC: 615
    Language: English
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    Keywords: Pharmacology. ; Immunology. ; Metabolism, Secondary. ; Plants. ; Botany. ; Pharmacology. ; Immunology. ; Plant Secondary Metabolism. ; Plant Science.
    Description / Table of Contents: Chapter 1. Immune system and mechanism of Immuno-modulation -- Chapter 2. Insights into the modulation of immune response, chemistry, and mechanisms of action of immuno-modulatory phytomolecules -- Chapter 3. Bioprospection and Clinical Investigations of Immunomodulatory Molecules -- Chapter 4. Pathway and genomics of immunomodulator natural products -- Chapter 5. Phytomolecules and metabolomics of immunomodulation - Recent Trends and Advances -- Chapter 6. Knowledge of African Traditional Medicine System: Immunomodulation -- Chapter 7. Middle Eastern diets as a potential source of immunomodulators -- Chapter 8. Immuno-Stimulant Properties of Some Commonly Used Indian Spices and Herbs with Special Reference to Region Specific Cuisines -- Chapter 9. Traditional Indian Knowledge of immunity from plants -- Chapter 10. Select Global Immune-Boosting Plants Used in Folklore Medicine -- Chapter 11. Immunomodulatory role of terpenoids and phytosteroids -- Chapter 12. Rhizomatous Plants – Curcuma longa and Zingiber officinale in affording immunity -- Chapter 13. Fruits as Boosters of Immune System -- Chapter 14. Solanaceous Plants for Immunomodulation -- Chapter 15. Food and vegetables as source of phytoactives for immunomodulation -- Chapter 16. Immunomodulation potential of woody plants -- Chapter 17. Biotechnological approaches for the production of immunomodulating phytomolecules -- Chapter 18. Technological mapping of plant-derived immunomodulator drugs: A patent-guided overview about species and its main compounds.
    Abstract: This book describes the process of immunomodulation and the plants which possess immunomodulation properties to boost the immune system. The immunomodulation process is highly relevant to address emerging as well as existing diseases in humans. A better immune system triggers the cellular responses for neutralizing and combating the onset of disease conditions. Chapters in the book discuss plants that have profound effects on the health and well-being of humans. They discuss the natural phytochemicals that have immense diversity and uniqueness of molecules. Molecules belonging to phenylpropanoids, terpenoids, steroids, alkaloids, and tannins etc possess a variety of pharmacological activities. The chapters describe how bioactive exert effects even when taken as part of the diet, supplement, and or as traditional herbal medicine. This book provides up-to-date scientific knowledge about the activities and mechanisms and leads in the area of medicinal plants and phytochemicals with immunomodulation properties. This book is meant for students, academics, researchers, and industry professionals interested in pharmacology, immunology, and plant secondary metabolites.
    Type of Medium: Online Resource
    Pages: XV, 541 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811681172
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Proteins . ; Human physiology. ; Biological transport. ; Cell membranes. ; Pharmacology. ; Protein Biochemistry. ; Human Physiology. ; Membrane Trafficking.
    Description / Table of Contents: 1. Classification and Gene Structure of Aquaporins -- 2. Protein Structure and Modification of Aquaporins -- 3. Expression Regulation and Trafficking of Aquaporins -- 4. Transport Characteristics of Aquaporins -- 5. Non-transport Functions of Aquaporins -- 6. The Evolutionary Aspects of Aquaporin Superfamily -- 7. Aquaporins in Nervous System -- 8. Aquaporins in Cardiovascular System -- 9. Aquaporins in Respiratory System -- 10. Aquaporins in Digestive System -- 11. Aquaporins in Urinary System -- 12. Aquaporins in Reproductive System -- 13. Aquaporins in Immune System.-14. Aquaporins in Eye -- 15. Aquaporins in Skin -- 16. Aquaporins in Glandular Secretion -- 17. Aquaporins in Fetal Development -- 18. Aquaporins in Diabetes Insipidus -- 19. Aquaporins in Edema -- 20. Aquaporins in Obesity.-21. Aquaporins in Tumor -- 22. Aquaporin Inhibitors -- 23. Non-aquaporin Water Channels.-24. Methods to Measure Water Permeability.
    Abstract: This book provides a state-of-the-art report on our current understanding of aquaporins and the future direction of the field. Aquaporins (AQPs) are a group of water-channel proteins that are specifically permeable to water and other small molecules, such as glycerol and urea. To date thirteen water-channel proteins (AQP0 – AQP12) have been cloned and the mechanisms and physiological functions of water transport across biological membranes have long been the subject of interest. Recent advances in the molecular biology and physiology of water transport have yielded new insights into how and why water moves across cell membranes, and studies on aquaporin knockout mouse models suggest that aquaporins are involved in the development of some diseases and they may be useful targets of research into selective-inhibitor drugs. By focusing on the advances made over the last 30 years in the biophysics, genetics, protein structure, molecular biology, physiology, pathophysiology and pharmacology of aquaporins in mammalian cell membranes, this book provides novel insights into further mechanisms and the physiological significance of water and some small molecule transport in mammals in order to stimulate further research in new directions. In the second version, fourteen chapters will be updated base on the most recent research articles. Ten new chapters will be added.
    Type of Medium: Online Resource
    Pages: VIII, 365 p. 1 illus. , online resource.
    Edition: 2nd ed. 2023.
    ISBN: 9789811974151
    Series Statement: Advances in Experimental Medicine and Biology, 1398
    DDC: 615
    Language: English
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    Keywords: Pharmacology. ; Pharmacy. ; Medical microbiology. ; Neurosciences. ; Pharmacology. ; Pharmacy. ; Medical Microbiology. ; Neuroscience.
    Description / Table of Contents: Part 1. Autonomic Nervous System -- Chapter 1. Cholinoceptor Agonists and Anticholinesterase Agents -- Chapter 2. Cholinoceptor Antagonists -- Chapter 3. Adrenergic Agonists -- Chapter 4. Adrenergic Antagonists -- Part 2. Central and Peripheral Nervous System -- Chapter 5. Neurotransmitters and Neurotransmission. Chapter 6. Hypnotics and Sedatives -- Chapter 7. Pharmacotherapy of Seizures -- Chapter 8. General Anesthetics -- Chapter 9. Drug Therapy of Psychosis and Mania -- Chapter 10. Pharmacotherapy of Depression and Anxiety Disorders Chapter 11. Pharmacotherapy of Neurodegenerative Disorders -- Chapter 12. Opioid Agonists and Antagonists -- Chapter 13. Cognition enhancers, Psychostimulants and Psychedelic Drugs -- Chapter 14. Drug Dependence and Abuse -- Chapter 15. Local Anesthetics -- Chapter 16. Skeletal muscle relaxants. Part 3. Autacoids and Other Chemical Mediators -- Chapter 17. Histamine, Serotonin, Bradykinin, and the Ergot Alkaloids -- Chapter 18. Prostaglandins, Leukotrienes and Related Compounds -- Chapter 19. Non-Steroidal Anti-Inflammatory Medicines -- Chapter 20. Drugs Used in Rheumatoid Arthritis -- Chapter 21. Pharmacotherapy of Gout -- Chapter 22. Nitric oxide, Vasoactive Peptides and Purines -- Part 4. Cardiovascular and Renal Pharmacology -- Chapter 23. Drugs Affecting Renal Excretory Function -- Chapter 24. Antihypertensive Agents -- Chapter 25. Treatment of Ischemic Heart Disease -- Chapter 26. Drugs Used in Heart Failure -- Chapter 27. Drugs Used in Cardiac Arrhythmias -- Chapter 28. Pharmacotherapy of Shock and Drugs Used in Cardiopulmonary Resuscitation -- Chapter 29. Treatment of Pulmonary Arterial Hypertension -- Chapter 30. Antiplatelets, Anticoagulants and Fibrinolytics -- Chapter 31. Drugs Used in Dyslipidemias -- Part 5. Pulmonary Pharmacology -- Chapter 32. Treatment of Asthma and COPD -- Chapter 33. Drugs Used in Cough and Rhinitis -- Part 6 Gastrointestinal Pharmacology -- Chapter 34. Drugs Used in Acid-Peptic Disorders -- Chapter 35. Drugs Affecting Gastrointestinal Motility -- Chapter 36. Antiemetics -- Chapter 37. Drug Therapy for Constipation -- Chapter 38. Antidiarrheal Agents -- Chapter 39. Irritable Bowel Syndrome -- Chapter 40. Pharmacotherapy of Inflammatory Bowel Disease -- Chapter 41. Miscellaneous Drugs Acting on the Gastrointestinal System -- Part 7. Endocrine Pharmacology -- Chapter 42. Hypothalamic and Pituitary Hormones -- Chapter 43. Pharmacotherapy of Diabetes Mellitus -- Chapter 44. Thyroid and Antithyroid Drugs -- Chapter 45. Adrenocorticosteroids and Their Antagonists -- Chapter 46. Gonadal Hormones and Their Inhibitors -- Chapter 47. Pharmacotherapy of Obesity -- Chapter 48. Drugs Affecting Bone Mineral Homeostasis -- Part 8. Hematopoietic System -- Chapter 49. Pharmacotherapy of Iron Deficiency and Other Related Anaemias -- Chapter 50. Pharmacotherapy of Vitamin B12 and Folic Acid Deficiency -- Chapter 51. Drug-Induced Blood Dyscrasias -- Part 9. Chemotherapy of Microbial Diseases -- Chapter 52. General Principles of Antimicrobial Therapy -- Chapter 53. Sulfonamides, Quinolones and Agents For Urinary Tract Infections -- Chapter 54. Penicillins, Cephalosporins and Other β-Lactam Antibiotics -- Chapter 55. Protein Synthesis Inhibitors -- Chapter 56. Antimycobacterial Drugs -- Chapter 57. Antifungal Drugs -- Chapter 58. Antiviral Drugs -- Chapter 59. Miscellaneous Antimicrobial Agents -- Chapter 60. Chemotherapy of Malaria and Other Protozoal Diseases -- Chapter 61. Chemotherapy of Helminthiasis -- Part 10. Pharmacotherapy of Neoplastic Disease -- Chapter 62. General Principles of Cancer Chemotherapy -- Chapter 63. Cytotoxic Drugs -- Chapter 64. Targeted Chemotherapy -- Chapter 65. Hormones Agents in the Pharmacotherapy of Cancer -- Chapter 66. Immunopharmacology -- Chapter 67. Dermatological Pharmacology -- Chapter 68. Ocular Pharmacology -- Chapter 69. Nutritional Supplements and Herbal Medicines -- Chapter 70. Immunoglobulins and Vaccines. .
    Abstract: This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences. .
    Type of Medium: Online Resource
    Pages: XXIV, 1175 p. 152 illus., 117 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813360099
    DDC: 615
    Language: English
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    Keywords: Pharmacology. ; Invertebrates. ; Medicine Research. ; Biology Research. ; Epidemiology. ; Biochemistry. ; Pharmacology. ; Invertebrate Zoology. ; Biomedical Research. ; Epidemiology. ; Biochemistry.
    Description / Table of Contents: Chapter 1. Introduction: The snakebite problem -- Chapter 2. Evolution of snakes and systematics of Big Four venomous snakes of India -- Chapter 3. Snake venom: Composition, evolution, function, and biomedical applications -- Chapter 4. Indian spectacled cobra (Naja naja) -- Chapter 5. Indian common Krait (Bungarus cerelus) -- Chapter 6. Indian Russell’s viper (Daboia russelii) -- Chapter 7. Indian Saw-scaled viper (Echis carinatus) -- Chapter 8. Prevention and Treatment of Big Four Snakebite in India.
    Abstract: This book provides detailed and updated knowledge about medically important ‘Big Four’ venomous snakes of India (Indian spectacled cobra, Indian common krait, Indian Russell’s viper, and Indian saw-scaled viper). This book essentially covers the snakebite problem in the world with particular reference to Asia and India. It discusses the evolution and systematics of venomous snakes, emphasizing ‘Big Four’ venomous snakes of India; the evolution and composition of venoms determined by traditional biochemical and modern proteomic analyses. It also describes the pharmacological properties of enzymatic and non-enzymatic toxins of ‘Big Four’ venomous snakes of India. Different chapters discuss exciting topics such as species-specific and geographical differences in venom composition and its impact on pathophysiology and clinical manifestations of snakebite envenomation in India, biomedical application of Indian snake venom toxins; production and quality assessment of commercial antivenom, prevention, and treatment of snakebite in India, adverse effects of antivenom including strategies to combat antivenom reactions inpatient. This book caters to toxinologists, pharmacologists, zoologists, antivenom manufacturers, biochemists, clinicians, evolutionary biologists, herpetologists, and informed non-specialists interested to know about the Indian snake venoms. .
    Type of Medium: Online Resource
    Pages: XI, 161 p. 55 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811628962
    DDC: 615
    Language: English
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    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Drug delivery systems. ; Biologicals. ; Biopharmaceutics. ; Toxicology. ; Biotechnology. ; Pharmacology. ; Drug Delivery. ; Biologics. ; Toxicology. ; Biotechnology.
    Description / Table of Contents: Chapter 1. Traditional Medical System (TMS) for Sustainable Healthcare in India -- Chapter 2. Modern Drug Discovery and Development for TB- The India Narrative -- Chapter 3. Indian Discovery Effort in the Quest of Novel Antibiotics -- Chapter 4. New Drug Discovery and Development in India to Counter Malaria -- Chapter 5. Modern Drug Discovery and Development in the area of Leishmaniasis -- Chapter 6. Modern Drug Discovery and Development: Diabetes and lifestyle disorders Part I – Introduction to Diabetes and Prevalence in India -- Chapter 7. Modern Drug Discovery and Development: Diabetes and lifestyle disorder Part II Type 2 Diabetes Mellitus: Marketed drugs and mechanisms -- Chapter 8. Modern Drug Discovery and Development: Diabetes and lifestyle disorders Part III Anti-diabetes research in India: Contributions from industrial organizations -- Chapter 9. Modern Drug Discovery and Development: Diabetes and lifestyle disorders Part IV Indian Academia Tryst with Cardio-metabolic Drug Discovery and Development -- Chapter 10. Modern drug discovery and development in the area of Cancer: Indian context -- Chapter 11. Biopharmaceutical development in India: recommendations on collaboration and innovation to enable affordable healthcare -- Chapter 12. Regulatory requirements and Quality Standards in India’s Clinical Trials Journey -- Chapter 13. Indian Pharma Perspective: New Drug Discovery and Development- Indian Pharmaceutical Industry.
    Abstract: Over the years, India has attained a prominent global position in the manufacture of Generic Drugs. This success can be attributed to its synthetic organic chemistry and chemical engineering strengths, nurtured by the timely policies of the Government of India. However, breakthrough successes in New Drug Discovery have remained elusive, despite the brilliant and sustained efforts of many Indian researchers and Pharma establishments. The Indian National Science Academy thought it appropriate to document India’s New Drug Discovery Research (NDDR) journey to date. Gathering contributions from prominent researchers in the Indian Pharma Industry and Academia, this book highlights their efforts, achievements, and the status quo of Indian NDDR. .
    Type of Medium: Online Resource
    Pages: XIII, 376 p. 191 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811580024
    DDC: 615
    Language: English
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  • 48
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Medicinal chemistry. ; Cancer. ; Microtechnology. ; Microelectromechanical systems. ; Pharmacovigilance. ; Pharmacology. ; Medicinal Chemistry. ; Cancer Biology. ; Microsystems and MEMS. ; Drug Safety and Pharmacovigilance.
    Description / Table of Contents: Chapter 1. Cancer -- Chapter 2. Types of cancer -- Chapter 3. Classification -- Chapter 4. Cancer or tumor nomenclature -- Chapter 5. Heterogeneity -- Chapter 6. Invasion and metastasis -- Chapter 7. How cancer arises? -- Chapter 8. Epidemiology -- Chapter 9. Economic burden -- Chapter 10. Treatment modalities -- Chapter 11. Chemotherapy -- Chapter 12. Properties of metals and metal complexes -- Chapter 13. Platinum based anticancer agents -- Chapter 14. Chemistry of cisplatin -- Chapter 15. Mechanism of action of platinum drugs -- Chapter 16. Non-platinum anticancer agents -- Chapter 17. Chemistry of gold -- Chapter 18. Gold and its complexes in medicine -- Chapter 19. Auranofin and its analogues -- Chapter 20. Classes of gold complexes -- Chapter 21. Mechanisms of action of anticancer gold complexes -- Chapter 22. Perspectives.
    Abstract: This book presents an overview of cancer and the genesis, and development of different treatment strategies and modalities against cancer. The emergence of gold and its complexes as promising anticancer chemotherapeutic agents have the potential to substitute or replace the platinum based chemotherapeutic agents. Gold complexes have demonstrated considerable anti-proliferative properties, chiefly attributed to their anti-mitochondrial effects, they make gold complexes excellent candidates as anti-cancer agents compared to their platinum-based counterparts. This book provides a critical review of recent advances made in the development of gold complexes as anti-cancer agents. In this context, it examines a number of different ligand architectures, provides comprehensive information on gold complexes’ mechanism of action and toxicity issues and, in closing, outlines future research directions.
    Type of Medium: Online Resource
    Pages: IX, 173 p. 124 illus., 29 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813363144
    DDC: 615
    Language: English
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    Keywords: Pharmacology. ; Drug delivery systems. ; Biotechnology. ; Pharmacology. ; Drug Delivery. ; Biotechnology.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Synthetic Strategies for the Generation of Molecularly Imprinted Polymers -- Chapter 3. Special Control by Molecular Imprinting Materials-zero-order Sustained Release, Enantioselective MIPs and Self-regulated Drug Delivery Microdevices -- Chapter 4. Water Compatible Molecularly Imprinted Polymers -- Chapter 5. Stimuli Responsive Imprinted DDS -- Chapter 6. MIP as Drug Delivery Systems for Dermal Delivery -- Chapter 7. MIP as Drug Delivery Systems of Anticancer Agents -- Chapter 8. MIP as Dug Delivery Systems of Ophthalmic Drugs -- Chapter 9. MIP as Drug Delivery Systems for Special Application -- Chapter 10. Outlook.
    Abstract: This book summarizes the recent advancements for drug delivery systems (DDS) in terms of fundamental principles, rapidly emerging techniques and developing frontiers of molecular imprinting. Especially with the combination of enantioselective molecularly imprinted polymers and water compatible molecularly imprinted polymers, stimuli responsive imprinted DDS have been innovated and applied to dermal delivery, ophthalmic drugs and cancer treatment. This philosophy comprehensively revolutionizes the treatment strategy of human healthcare and provides the possibility to re-trigger in vivo an exhaust system after the complete release of the starting drug cargo, thus enabling precision medicine. To this end, the following unique features will be discussed and concluded: 1) State-of-the-art definition of MIP as drug delivery systems. 2) Advanced techniques and clinical applications of MIP as drug delivery systems in the past decade. 3) Novel frontiers and brand-new technologies, for example, drug delivery devices for zero-order sustained release and stimuli responsive imprinted DDS. 4) Revolutionary impact on dermal delivery, ophthalmic drugs and cancer treatment. 5) Future challenges and perspectives.
    Type of Medium: Online Resource
    Pages: VII, 216 p. 108 illus., 68 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811602276
    DDC: 615
    Language: English
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  • 50
    Keywords: Pharmacology. ; Metabolism, Secondary. ; Plants. ; Agricultural biotechnology. ; Plant biotechnology. ; Pharmacology. ; Plant Secondary Metabolism. ; Agricultural Biotechnology. ; Plant Biotechnology.
    Description / Table of Contents: Chapter 1. Plant Secondary Metabolites: An Introduction of their Chemistry and Biological significance with Physico-Chemical aspect -- Chapter 2. Natural sources of plant secondary metabolites and role of plant polyphenols in the green photosynthesis of metallic nanoparticles -- Chapter 3. Plant secondary metabolites determination through analytical chromatographic techniques: Recent trends and advancement -- Chapter 4. Role of plant secondary metabolites as Anticancer and Chemopreventive agent -- Chapter 5. Plant Secondary Metabolites: Natural Compounds As Cosmetic Ingredients And Their Potential Activity In Skin Cancer -- Chapter 6. Natural remedies for a healthy heart. The evidence based beneficial effects of polyphenols -- Chapter 7. Kauranes as Anti-inflammatory and Immunomodulatory Agents: An Overview of In Vitro and In Vivo Effects -- Chapter 8. Role of plant secondary metabolites in metabolic disorders -- Chapter 9. Metal Complexes of plant secondary metabolites with therapeutic potential. Chapter 10. Phytoalexins: Implications in plant defense and human health -- Chapter 11. Secondary metabolites from plants: Role in plant diseases and health care -- Chapter 12. Plant Secondary metabolites: Their food and therapeutic importance -- Chapter 13. Role of plant secondary metabolites as modulators of multidrug resistance in cancer thera -- Chapter 14. Plant Secondary Metabolites: functions in plants and pharmacological importance -- Chapter 15. Plant Secondary Metabolities in Antiviral Applications.
    Abstract: Plant secondary metabolites are plant-based natural products that display a variety of pharmacological effects. This book discusses the invaluable bioactivity and multifaceted potential of these compounds. The book describes the physico-chemical and biochemical aspects of the plant secondary metabolites along with the chemistry, therapeutics and future perspectives of these plant secondary metabolites. Moreover, the book also discusses about various sources of plant secondary metabolites, and the metabolite determination through various analytical techniques. It further describes the potential applications of plant secondary metabolites as anticancer and chemo preventive agents, their role as cosmetic ingredients and activity in skin cancer therapy. Further chapters emphasize upon the plethora of roles of plant secondary metabolites, including those as antivirals, anti-bacterial, anti-inflammatory drugs, cardioprotective agents etc. The book culminates with chapters on the impact of certain plant secondary metabolites in plant defence and human healthcare. This book is meant for researchers and students in the field of pharmacology and plant sciences. Moreover, this book is also useful for industry experts especially working in the field of herbal therapeutics.
    Type of Medium: Online Resource
    Pages: IX, 482 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811647796
    DDC: 615
    Language: English
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  • 51
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Veterinary medicine. ; Stem cells. ; Veterinary Science. ; Veterinary Clinical Medicine. ; Stem Cell Biology.
    Description / Table of Contents: Chapter 1: Mesenchymal stem cells therapeutic applications in cartilage regeneration -- Chapter 2: Mesenchymal stem cells therapeutic applications in bone regeneration -- Chapter 3: Mesenchymal stem cells therapeutic applications in muscle, tendon and ligament regeneration -- Chapter 4: Mesenchymal stem cells therapeutic applications in peripheral nervous system disorders -- Chapter 5: Mesenchymal stem cells therapeutic applications in central nervous system disorders -- Chapter 6: Mesenchymal stem cells therapeutic applications in cardiovascular disorders -- Chapter 7: Mesenchymal stem cells therapeutic applications in gastrointestinal disorders -- Chapter 8: Mesenchymal stem cells therapeutic applications in lung disorders -- Chapter 9: Mesenchymal stem cells in reproductive system: reproductive and therapeutic applications -- Chapter 10: Mesenchymal stem cells therapeutic applications in urinary system disorders -- Chapter 11: Mesenchymal stem cells therapeutic applications in integumentary system disorders -- Chapter 12: Mesenchymal stem cells therapeutic applications in endocrine disorders -- Chapter 13: Mesenchymal stem cells therapeutic applications in eye and adnexa ailments.
    Abstract: This book reviews the potential therapeutic and reproductive applications of mesenchymal stem cells in veterinary regenerative and reproductive medicine. The systemic approach focuses on musculoskeletal structures like cartilage, bone, muscle, tendon, ligaments and nervous tissues. It also focuses on other body systems like gastrointestinal, cardiovascular, urogenital, respiratory and integumentary system. Besides, the special glands or organs like endocrine glands and eye and its adnexa are also focused. The book chapters discusses the problems and the need for regenerative medicine employing MSCs. It provides an ex vivo basis of MSCs therapeutics and reproductive potential followed by their in vivo applications. The book further provides an understanding on the behavior and mechanisms of action of mesenchymal stem cells. The book also abridges challenges and provides future prospects of mesenchymal stem cells in clinical and reproductive applications. As such, the book offers a valuable resource for students, veterinarians, and scientists working in the regenerative and reproductive sciences in human and veterinary medicine.
    Type of Medium: Online Resource
    Pages: XVII, 408 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811932779
    DDC: 636.089
    Language: English
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  • 52
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Alternative medicine. ; Pharmacy. ; Pharmacology. ; Complementary and Alternative Medicine. ; Pharmacy.
    Abstract: This book describes the essential and cutting-edge concepts based on the frontier of pharmaceutical research in TCM, underlying scientific principles, and current advancements of drug delivery systems for Chinese medicines, including sustained-release drug delivery systems, trans-nasal drug delivery systems, dermal and transdermal drug delivery systems, etc. Novel carriers and emerging technologies (such as 3D printing) are also covered. The book provides readers with an overall picture of drug delivery systems for Chinese medicines and also yields benefits for the pharmaceutical industry with regard to TCM-based drug development.
    Type of Medium: Online Resource
    Pages: XIII, 336 p. 1 illus. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811634444
    DDC: 615
    Language: English
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  • 53
    Keywords: Veterinary medicine. ; Physiology. ; Bioclimatology. ; Veterinary Science. ; Animal Physiology. ; Climate Change Ecology.
    Abstract: This book describes the importance of sustainable livestock production from a food security perspective in the changing climate scenario. It covers the amelioration of climate change impacts and describes the various mitigation strategies to reduce enteric methane emissions. The book targets sustainable livestock production by covering diverse concepts of amelioration, mitigation, and policy up-gradation. Further, it examines various adverse impacts of climate change on growth, meat, milk, and reproduction in livestock. Most importantly, the book covers novel aspects of quantifying heat stress response of livestock based on non-invasive methodologies, including infrared thermal imaging, sensor-based applications, hair, urine, and fecal cortisol estimation. Particular emphasis was given to describing the skin-based novel approaches to establish climate resilience in indigenous breeds. The book provides detailed descriptions of alleviating climate change impacts on shelter management, nutritional interventions, and genetics-based strategies involving advanced genomic tools. Lastly, it highlights the livestock species which could be considered ideal climate-resilient animal models to withstand the adversities associated with climate change.
    Type of Medium: Online Resource
    Pages: XXV, 321 p. 48 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811698361
    DDC: 636.089
    Language: English
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  • 54
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Veterinary medicine. ; Genetics. ; Biotechnology. ; Fertility, Human. ; Veterinary Science. ; Genetics and Genomics. ; Biotechnology. ; Fertility.
    Description / Table of Contents: Chapter 1. Buffalo in the World: Situation and Perspectives -- Chapter 2. Water buffalo genomic diversity -- Chapter 3. Advances in Buffalo Breeding: A Journey from classical Breeding to Genomic Selection -- Chapter 4. Reproductive Management of Dairy Buffaloes -- Chapter 5. Behavior and welfare of dairy buffaloes: calving, weaning and milking -- Chapter 6. Buffalo’s milk and its products: Composition, Nutrition, and Benefits -- Chapter 7. Welfare of buffaloes at slaughter -- Section-II Omics approaches to understand buffalo’s genome, physiology, and reproduction -- Chapter 8. Molecular evolution and genome architecture of water buffalo (Bubalus bubalis), the ‘living bank’ for marginal farmers in developing countries -- Chapter 9. Fertility biomarkers in buffalo -- Chapter 10. Being Sweet is Being Smart: Lessons Learnt from Buffalo Spermatozoa -- Chapter 11. Protein signatures of lactation and early pregnancy diagnosis in buffalo (Bubalus bubalis) -- Chapter 12. Induced pluripotent stem cells in buffalo: Basics to translation applications -- Chapter 13. Domesticated buffalo- A model for human biomedical research -- Section-III Reproductive Biotechnologies -- Chapter 14. Advances in embryo production in buffaloes: in vivo versus in vitro procedures -- Chapter 15. Application of Fixed-Time Artificial Insemination in Water Buffaloes -- Chapter 16. Semen sexing in buffalo -- Chapter 17. Advances in cryopreservation of buffalo semen -- Chapter 18. Advances in Semen Quality Assessments in AI Programs in Buffalo -- Chapter 19. Reproductive ultrasonography in buffalo – Basic concepts and recent advances -- Chapter 20. Spermatogonial stem cells and testis-tissue cryopreservation as a tool for conservation of buffalo germplasm -- Chapter 21. Somatic Cell Nuclear Transfer and its Applications in Buffalo (Bubalus bubalis).
    Abstract: This book comprehensively reviews the advancements in biotechnological applications for the enhanced production and conservations of buffalo (Bubalus bubalis). The book discusses developments in assisted reproduction to improve productivity and the produce novel products for applications to human health and nutrition. The initial chapters of the book discuss the global distribution and domestications of buffalo, and nutritive values of buffalo milk, while the subsequent sections examine the applications of the genome-wide association traits to identify potential genetic variants affecting important economic traits. It identifies predictive biomarkers for postpartum or peripartum diseased-state and presents potential protein biomarkers for the diagnosis of early pregnancy in buffalo. Lastly, it discusses recent scientific developments such as induced pluripotent stem cells, spermatogonial stem cells, somatic cell nuclear transfer, and buffalo as a model for human biomedical research. This book is a useful source to students, academicians, researchers, and policymakers who are involved in buffalo science and industry.
    Type of Medium: Online Resource
    Pages: XII, 457 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811675317
    DDC: 636.089
    Language: English
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  • 55
    Keywords: Veterinary medicine. ; Genetics. ; Biotechnology. ; Veterinary Science. ; Genetics and Genomics. ; Biotechnology.
    Description / Table of Contents: Module 1_Functional Genomics and Proteomics -- Module 2_Microbial Genomics and Novel Biotechnological approaches to enhance animal health -- Module 3_Bioinformatics, Big Data, and Integrated Omics.
    Abstract: This book comprehensively discusses the applications of molecular genetics, functional and structural genomics, and proteomics vis-a-vis bioinformatics, artificial intelligence, and robotics in livestock healthfulness and productivity. It reviews the biotechnological approaches in veterinary sciences for increasing productivity and resistance to disease. The book emphasizes the approaches based on artificial intelligence to analyze the data collected on animals, pathogens, and their environment. It underscores artificial intelligence applications in disease diagnosis, epidemiological studies, and detecting biological phenomena, including heat-detection, pregnancy, docility, and infections. Further, the book examines the genomics and proteomics approaches for understanding the gut microbiota and the role of pathogen-host interactions in animal health and disease. Lastly, it explores both pathogenic and non-pathogenic microbial transfer between humans, animals, and the environment across one health spectrum.
    Type of Medium: Online Resource
    Pages: XXVI, 451 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819922093
    Series Statement: Livestock Diseases and Management,
    DDC: 636.089
    Language: English
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  • 56
    Keywords: Veterinary medicine. ; Animal culture. ; Animal biotechnology. ; Veterinary Science. ; Animal Science. ; Animal Biotechnology.
    Description / Table of Contents: Chapter 1_Vitellogenin: Outline and History -- Chapter 2_Previtellogenesis and Vitellogenesis -- Chapter 3_Diversification and classification of Vitellogenin in fishes -- Chapter 4_State-of-art of multiple vitellogenin systems in fishes -- Chapter 5_Tools for identification and characterization of Vitellogenin -- Chapter 6_Functional aspects of Vitellogenin in oogenesis and its regulatory mechanism -- Chapter 7_Role of Vitellogenin as immunocompetent molecule -- Chapter 8_Vitellogenesis and Reproductive Strategies -- Chapter 9_Vitellogenin: as a hormone -- Chapter 10_Vitellogenin as a biomarker -- Chapter 11_Fish vitellogenin induction and its related egg yolk proteins -- Chapter 12_Vitellogenin receptors in fishes -- Chapter 13_Molecular cloning and induction of vitellogenins -- Chapter 14_Significance of Vitellogenin in egg yolk production and egg quality -- Chapter 15_Concentration of Vitellogenin and disruption of the endocrine system in Fish -- Chapter 16_Biological activities of Vitellogenin and its mechanism -- Chapter 17_Multivalent properties of Vitellogenin in marine and freshwater fishes. -Chapter 18_Effect of Vitellogenin in growth of ornamental fishes -- Chapter 19_Future prospective of Vitellogenin research. .
    Abstract: This book provides basic and advanced information on vitellogenin in fish. The proposed book discusses the history of vitellogenin, previtellogenesis, their diversification and classification in fishes, and tools for their identification and characterization. Further, their functional aspects in oogenesis and its regulatory mechanism, role as the immunocompetent molecule, and reproductive strategies are discussed. The book further examines vitellogenin as a hormone and biomarker, its related egg yolk proteins, and its mechanism on molecular cloning and induction. In addition, the book discusses its role in the disruption of the endocrine system in fish, its biological activities, its multivalent mechanism in marine and freshwater fishes, and its impact on the growth of ornamental fishes. Moreover, this book elaborates on the multiple vitellogenin genes, each with unique promoter regions and varying sensitivity to induction by estradiol, and multiple Vtg proteins themselves, with variable degrees of post-translational modification. As such, this book is helpful for researchers and students interested in the reproduction of fishes and reproductive biology. .
    Type of Medium: Online Resource
    Pages: XVI, 281 p. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819953400
    DDC: 636.089
    Language: English
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  • 57
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Veterinary medicine. ; Orthopedics. ; Veterinary Science. ; Veterinary Clinical Medicine. ; Orthopaedics.
    Description / Table of Contents: Module 1_Basic Considerations -- Module 2_Principles of Fracture Fixation Techniques -- Module 3_ Management of Specific Fractures in Small Animals -- Module 4_Management of Specific Fractures in Large Animals.
    Abstract: This textbook emphasizes the fundamentals of bone fracture and its fixation, including advanced techniques of osteosynthesis in both small and large animals. Various fracture fixation techniques and devices have been described in simple language with the help of sketches and photographs. The chapter on the basic considerations in fracture fixation narrates bone structure and types, bone development and growth regulation, types of fracture and fracture healing, first aid and emergency treatment, selection of fracture fixation technique, anesthetic management, and fracture fixation implants and instruments. The book highlights principles of different external, internal, and external skeletal fixation techniques. It also presents various basic and advanced techniques used to manage specific fractures in different bones, separately for small and large animal patients. It also includes specific topics like fracture fixation in young, osteoporotic, and avian bones, open fracture management, bone grafts and scaffolds, and fracture fixation complications. Towards the end, the book elucidates miscellaneous but essential topics in veterinary orthopedics such as metabolic bone diseases, antebrachial bone deformities, joint luxations, arthritis, common tendon, and ligament injuries, bone tumors, and physiotherapy and rehabilitation of patients. This textbook is essential reading for veterinary students, practitioners, and researchers working in veterinary orthopedic surgery.
    Type of Medium: Online Resource
    Pages: XVIII, 459 p. 342 illus., 118 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819925759
    DDC: 636.089
    Language: English
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  • 58
    Keywords: Pharmacology. ; Epigenetics. ; Respiratory organs. ; Physiology. ; Pharmacology. ; Epigenetics. ; Respiratory Physiology.
    Description / Table of Contents: Chapter 1. Introduction to Lung Diseases -- Chapter 2. Introduction to Epigenetics -- Chapter 3._Epigenetic mechanisms in Inflammation -- Chapter 4. Epigenetic regulator of inflammatory gene expression -- Chapter 5. Epigenetics of Asthma -- Chapter 6_. Epigenetic optimization in chronic obstructive pulmonary disease (COPD -- Chapter 7. Epigenetics of Lung Cancer -- Chapter 8. Epigenetics of Pulmonary Tuberculosis -- Chapter 9. Epigenetics of Idiopathic Pulmonary Fibrosis -- Chapter 10. Epigenetics of influenza-A virus infection -- Chapter 11. Epigenetics of rhinovirus -- Chapter 12. Epigenetics of SARS-Cov2 (Covid-19) -- Chapter 13. Epigenetics of Haemophilus Influenzae -- Chapter 14. Future Prospects and Challenges -- Chapter 15. Targeting epigenetics in pulmonary arterial hypertension.
    Abstract: This book discusses the role of epigenetics in pathogenesis of different pulmonary diseases, including chronic obstructive pulmonary disease, lung cancer, pulmonary tuberculosis, idiopathic pulmonary fibrosis and pulmonary infections. It also explores post-translational modifications in DNA and histones for improving the understanding of lung diseases. This book helps in understanding the epigenetic mechanisms towards the development of novel diagnostic and therapeutic approaches. Further, the book provides insight into the underlying molecular mechanisms involved in the epigenetic regulation of inflammation, which may have novel implications in designing small molecule inhibitors that target the epigenetic machinery for the effective treatment of a variety of inflammation‑related diseases. This book is a valuable resource for academics, research and industry professionals working in respiratory biology.
    Type of Medium: Online Resource
    Pages: XV, 266 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819947805
    DDC: 615
    Language: English
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