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  • Books  (6)
  • E-Books: Biomedical and Life Sciences (AWI only)  (6)
  • Biotechnology.  (6)
  • Cham :Springer International Publishing :  (6)
  • English  (6)
  • 612.028  (6)
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  • Books  (6)
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  • E-Books: Biomedical and Life Sciences (AWI only)  (6)
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  • Cham :Springer International Publishing :  (6)
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  • English  (6)
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  • 1
    Online Resource
    Online Resource
    Engineering Translational Models of Lung Homeostasis and Disease (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Regenerative medicine. ; Biomedical engineering. ; Cytology. ; Biomaterials. ; Cells. ; Biotechnology. ; Regenerative Medicine and Tissue Engineering. ; Biomedical Engineering and Bioengineering. ; Cell Biology. ; Biomaterials-Cells. ; Biotechnology. ; Biomaterials.
    Abstract: Cutting-edge engineering approaches towards modelling lung homeostasis and disease have created dynamic new opportunities for interdisciplinary collaboration and unprecedented progress toward understanding and treating lung disease. This text connects established research in lung biology and physiology to innovative engineering strategies for pulmonary modelling. This unique approach aims to encourage and facilitate progress among a greater audience of basic and translational scientists, clinicians, and medical practitioners. Engineering Translational Models of Lung Homeostasis and Disease illustrates the advances in lung tissue characterization, revealing dynamic changes in the structure, mechanics, and composition of the extracellular matrix. This information paves the way for tissue-informed engineering models of pulmonary tissue, improved design of clinical materials, and advances against a variety of common pathologies. Current translational challenges are highlighted, as are engineering opportunities to overcome these barriers. This foundational text holds valuable lessons for researchers and clinicians throughout the fields of engineering, materials science, cell biology, pulmonary medicine, and clinical science. Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: X, 326 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031266256
    Series Statement: Advances in Experimental Medicine and Biology, 1413
    URL: https://doi.org/10.1007/978-3-031-26625-6
    DOI: 10.1007/978-3-031-26625-6
    DDC: 612.028
    Language: English
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  • 2
    Online Resource
    Online Resource
    Bio-Materials and Prototyping Applications in Medicine (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Regenerative medicine. ; Biomedical engineering. ; Biomaterials. ; Biotechnology. ; Engineering design. ; Regenerative Medicine and Tissue Engineering. ; Biomedical Engineering and Bioengineering. ; Biomaterials. ; Biotechnology. ; Engineering Design.
    Description / Table of Contents: Metallic and Ceramic Biomaterials: Current and Future Developments -- Polymers, Composites and Nano Biomaterials: Current and Future Developments -- Polyurethane Based Materials with Applications in Medical Devices -- Rapid Prototyping of Hydrogels to Guide Tissue Formation -- Engineered Scaffold Architecture Influences Soft Tissue Regeneration -- Customized Implants for Bone Replacement and Growth -- Direct Digital Manufacturing of Complex Dental Prostheses -- Digital Design and Fabrication in Dentistry -- The Development of an Artificial Finger Joint -- Computer-Aided Development of Mega Endo-Prostheses -- Smart Insoles -- Medical Applications of Additive Manufacturing -- Additive Manufacturing in Craniofacial Applications -- Additive Manufacturing in Hearing Aids.
    Abstract: This second edition maintains a focus on integrated biomaterials, computer-aided design, and physical prototyping techniques as examples of the materials and applications that are found in medical environments. All original chapters, written by renowned experts in the field, have been updated along with the addition of four new chapters on: Smart insoles Medical applications of additive manufacturing Additive manufacturing in craniofacial applications Additive manufacturing in hearing aids This wide-ranging treatise on biomaterials and prototyping applications in medicine also focuses on solid freeform fabrication, rapid prototyping, layered manufacturing, and computer-aided design in the development of prosthetic devices. This book is a must-have for bioengineers seeking a comprehensive overview of this important subject and examples of medical applications, as well as researchers and academics in the same field. .
    Type of Medium: Online Resource
    Pages: XII, 200 p. 104 illus., 60 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030358761
    URL: https://doi.org/10.1007/978-3-030-35876-1
    DOI: 10.1007/978-3-030-35876-1
    DDC: 612.028
    Language: English
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  • 3
    Online Resource
    Online Resource
    An Introduction to Veterinary Medicine Engineering (2023)
    Cham :Springer International Publishing :
    Details
    Keywords: Regenerative medicine. ; Veterinary medicine. ; Animal biotechnology. ; Biomedical engineering. ; Biotechnology. ; Regenerative Medicine and Tissue Engineering. ; Veterinary Science. ; Animal Biotechnology. ; Biomedical Engineering and Bioengineering. ; Biotechnology.
    Abstract: Do cephalopods change color when under distress? Is the reptilian heart analogous to a diaphragm positive displacement pump? Are digital twins the answer for animal experimentation? This book explores the new field of veterinary engineering science and discusses how to better measure vital signs in exotic and companion animals. A vast opportunity exists for developing novel technologies that target reductions to the number of invasive procedures patients are subjected to. We examine improvements to animal care and enhancement of animal welfare while creating a more sustainable veterinary healthcare ecosystem. The authors address the challenges engineers face in designing healthcare equipment for animals and how the field of veterinary engineering contributes to traditional veterinary medicine. This book brings a novel field of engineering to train future veterinarians and engineers on design and application of technology to veterinary medicine.
    Type of Medium: Online Resource
    Pages: XI, 156 p. 25 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031228056
    URL: https://doi.org/10.1007/978-3-031-22805-6
    DOI: 10.1007/978-3-031-22805-6
    DDC: 612.028
    Language: English
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  • 4
    Online Resource
    Online Resource
    Bone Tissue Engineering : Bench to Bedside Using 3D Printing (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Regenerative medicine. ; Biotechnology. ; Biomaterials. ; Biomedical engineering. ; Regenerative Medicine and Tissue Engineering. ; Biotechnology. ; Biomaterials. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: 1. Introduction (market, clinical need, bone grafts) a. Choice 1: Alan S Herford, DDS, MD (Loma Linda University) -- 2. Basic bone biology a. Choice 1: David T Scadden, MD (Massachusetts General Hospital) -- 3. Principles of bone tissue engineering a. Choice 1: Antonios G Mikos, PhD (Rice University) b. Choice 2: Susmita Bose, PhD (Washington State University) -- 4. Additive manufacturing technologies a. Choice 1: Anthony Atala, MD (Wake Forest School of Medicine) b. Choice 2: Jennifer A Lewis, ScD (Harvard University) -- 5. 3D printing scaffolds for oral and maxillofacial regeneration a. Choice 1: Fernando PS Guastaldi, PhD (Massachusetts General Hospital) and Maria J Troulis, MsC (Massachusetts General Hospital) -- 6. 3D printing scaffolds for orthopedic joint tissue engineering a. Choice 1: Anthony J Melchiorri, PhD (Rice University) -- 7. 3D bioprinting and nanotechnology for bone tissue engineering a. Choice 1: Bhushan Mahadik, PhD (University of Maryland) -- 8. Bioreactors and scale-up in bone tissue engineering a. Choice 1: John P Fisher, PhD (University of Maryland) -- 9. Commercialization, legal, and regulatory considerations to translate 3D printing-based products to the marketplace and the clinic a. Choice 1: Anthony Ratcliffe, PhD (Synthasome, Inc.) -- 10. Future directions and challenges a. Choice 1: James J Yoo, PhD (Wake Forest School of Medicine) b. Choice 2: Fernando PS Guastaldi, PhD (Massachusetts General Hospital) and Bhushan Mahadik, PhD (University of Maryland).
    Abstract: This book provides a comprehensive overview of the state-of-the-art research as well as current challenges and strategies to reconstruct large bone defects employing 3D printing technology. Various topics covered include different 3D printing technologies that can be applied for bioengineering bone, the aspects of basic bone biology critical for clinical translation, tissue engineering platforms to investigate the bone niche microenvironment, the pathway to clinical translation, and regulatory hurdles. Bone Tissue Engineering: State-of-the-Art in 3D Printing is an ideal book for students and researchers interested in learning more about the latest advances in employing different 3D printing technologies for bone tissue engineering. .
    Type of Medium: Online Resource
    Pages: XIII, 317 p. 81 illus., 74 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030920142
    URL: https://doi.org/10.1007/978-3-030-92014-2
    DOI: 10.1007/978-3-030-92014-2
    DDC: 612.028
    Language: English
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  • 5
    Online Resource
    Online Resource
    The Computational Mechanics of Bone Tissue : Biological Behaviour, Remodelling Algorithms and Numerical Applications (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Regenerative medicine. ; Biomedical engineering. ; Biotechnology. ; Mechanical engineering. ; Mathematics Data processing. ; Regenerative Medicine and Tissue Engineering. ; Biomedical Engineering and Bioengineering. ; Biotechnology. ; Mechanical Engineering. ; Computational Science and Engineering.
    Description / Table of Contents: Part I: Biological Characterization of Bone Tissue -- Chapter 1. Bone: functions, structure and physiology -- Chapter 2. Bone Quality Assessment at the Atomic Scale -- Part II: Bone Remodelling algorithms -- Chapter 3. Meshless, Bone Remodelling and Bone Regeneration Modelling -- Chapter 4. Dynamic biochemical and cellular models of bone physiology: integrating remodeling processes, tumor growth and therapy -- Chapter 5. Mathematical Modelling of Spatio-Temporal cell dynamics observed during Bone Remodelling -- Chapter 6. A Mechanostatistical Approach to Multiscale Computational Bone Remodelling -- Part III: Numerical simulation of bone tissue and adjacent structures -- Chapter 7. Finite Element Analysis of Bone and Experimental Validation -- Chapter 8. Computational modelling of tissue engineered cartilage constructs -- Chapter 9. On the Computational Biomechanics of the Intervertebral Disc -- Index.
    Abstract: This book offers a timely snapshot of computational methods applied to the study of bone tissue. The bone, a living tissue undergoing constant changes, responds to chemical and mechanical stimuli in order to maximize its mechanical performance. Merging perspectives from the biomedical and the engineering science fields, the book offers some insights into the overall behavior of this complex biological tissue. It covers three main areas: biological characterization of bone tissue, bone remodeling algorithms, and numerical simulation of bone tissue and adjacent structures. Written by clinicians and researchers, and including both review chapters and original research, the book offers an overview of the state-of-the-art in computational mechanics of bone tissue, as well as a good balance of biological and engineering methods for bone tissue analysis. An up-to-date resource for mechanical and biomedical engineers seeking new ideas, it also promotes interdisciplinary collaborations to advance research in the field.
    Type of Medium: Online Resource
    Pages: XIV, 241 p. 68 illus., 45 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030375416
    Series Statement: Lecture Notes in Computational Vision and Biomechanics, 35
    URL: https://doi.org/10.1007/978-3-030-37541-6
    DOI: 10.1007/978-3-030-37541-6
    DDC: 612.028
    Language: English
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  • 6
    Online Resource
    Online Resource
    Cell-Inspired Materials and Engineering (2021)
    Cham :Springer International Publishing :
    Details
    Keywords: Regenerative medicine. ; Biomaterials. ; Medical microbiology. ; Biological transport. ; Cell membranes. ; Biotechnology. ; Biomedical engineering. ; Regenerative Medicine and Tissue Engineering. ; Biomaterials. ; Medical Microbiology. ; Membrane Trafficking. ; Biotechnology. ; Biomedical Engineering and Bioengineering.
    Description / Table of Contents: 1. Generation of hepatocytes for human ES/iPS cells for regenerative medicine -- 2. Construction of multi-step catalytic systems in protein assemblies -- 3. Machine learning and Monte Carlo methods for surface-assisted molecular self-assembly -- 4. DNA nanotechnology to disclose molecular events at the nanoscale and mesoscale levels -- 5. Materials designed for biological nitric oxide delivery -- 6. Designing bio-mimicking synthetic transcription factors for therapeutic gene modulation -- 7. Magnetic nanoparticles and alternating magnetic field for cancer therapy: From cells to clinics -- 8. Light-control of cell membrane potential and its environment -- 9. Physical concepts towards cell-material integration -- 10. Using stem cells and synthetic scaffolds to model ethically sensitive human placental tissue -- 11. Nanofiber extracellular matrices in regenerative medicine.
    Abstract: This book highlights cutting-edge studies in the development of cell-inspired biomaterials and synthetic materials that manipulate cell functions and provide the next generation with contemporary tools for treating complex human diseases. It explores the convergence of synthetic materials with cell and molecular biology and surveys how functional materials, when patterned with spatial and temporal precision, can be used effectively to maintain cell proliferation and phenotype in vitro, to trigger specific cell functions, and to redirect cell-fate decisions. Human stem cells are a frequently discussed subject in this book. This is an ideal book for students, cell biologists, researchers interested in interdisciplinary research, and biomedical engineers. This book also: Highlights successfully developed technologies in cell engineering that make possible new therapeutic development for previously untreatable conditions Covers topics including bio-inspired micro patterning, DNA origami technology, synthetic NOS inspired by compartmentalized signaling in cells, and light-induced depolarization of the cell membrane Illustrates in detail the use of stem cells and synthetic scaffolds to model ethically sensitive embryonic tissues and organs.
    Type of Medium: Online Resource
    Pages: VIII, 257 p. 89 illus., 74 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030559243
    Series Statement: Fundamental Biomedical Technologies,
    URL: https://doi.org/10.1007/978-3-030-55924-3
    DOI: 10.1007/978-3-030-55924-3
    DDC: 612.028
    Language: English
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