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  • Books  (12)
  • Journals
  • E-Books: Biomedical and Life Sciences (AWI only)  (12)
  • Neurosciences.  (12)
  • 2020-2024  (12)
  • 571.6  (7)
  • 660.6  (5)
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  • Books  (12)
  • Journals
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  • E-Books: Biomedical and Life Sciences (AWI only)  (12)
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  • 2020-2024  (12)
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  • 1
    Online Resource
    Online Resource
    Tight Junctions (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Cytology. ; Neurosciences. ; Medicine Research. ; Biology Research. ; Pharmacology. ; Cell Biology. ; Neuroscience. ; Biomedical Research. ; Pharmacology.
    Description / Table of Contents: A historical and evolutionary view of tight junctions -- Tricellular tight junctions -- Mechanosensitivity of tight junctions -- Intracellular traffic and non-canonical roles of ZO-2 protein -- Impact of claudin-2 and occludin expression in inflammation disorders -- Tight junctions in the inflamed gut -- Intestinal barrier disruption by enteropathogenic Escherichia coli -- Tight junction barrier function regulation by microbiota -- Claudin-7 participation in cell-substrate adhesion, cell migration, salt balance in the renal collecting duct and gut cell renewal and differentiation -- Regulation of the alveolar epithelial barrier by claudin-5 -- Regulation of the blood-retinal barrier by occludin phosphorylation, norrin and sonic hedgehog signaling -- Transmigration of metastatic cells through the blood-brain barrier -- Endocytosis of tight junction proteins -- Regulated degradation of claudins. .
    Abstract: This volume explores the dynamic topic of tight junctions. The book focuses on tight junctions' role in sealing adjacent epithelial cells in a narrow band just beneath their apical surface. The book explains how tight junctions consist of a network of claudins and other proteins, and delves into how they hold cells together and form functional and protective barriers, regulating the passage of molecules and ions through the space between cells. The book opens with a discussion of the evolution of research on tight junctions, discussing a range of primary areas of growth, including the current knowledge on the particular physiological function of different claudins due to the development of an array of knock out mice. The chapters also explore in-depth studies of tight junctions in specific tissues (gut, lung and endothelia). This book offers a comprehensive understanding on post-translational modifications of occludin and its impact on tight junction function, as well as the molecular composition and function of tricellular tight junctions. This volume is particularly relevant to students and scientists in neuroscience, cell biology, physiology, cell differentiation, and cancer research.
    Type of Medium: Online Resource
    Pages: XII, 334 p. 47 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030972042
    URL: https://doi.org/10.1007/978-3-030-97204-2
    DOI: 10.1007/978-3-030-97204-2
    DDC: 571.6
    Language: English
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  • 2
    Online Resource
    Online Resource
    Proteostasis and Disease : From Basic Mechanisms to Clinics (2020)
    Cham :Springer International Publishing :
    Details
    Keywords: Cytology. ; Neurosciences. ; Immunology. ; Medicine Research. ; Biology Research. ; Cancer. ; Cell Biology. ; Neuroscience. ; Immunology. ; Biomedical Research. ; Cancer Biology.
    Description / Table of Contents: Part I. Cancer -- Ubiquitin-Regulated Cell Proliferation and Cancer -- Ubiquitin, SUMO, and Nedd8 as Therapeutic Targets in Cancer -- The Proteasome System in Health and Disease -- Proteostasis Dysregulation in Pancreatic Cancer -- Divergent Modulation of Proteostasis in Prostate Cancer -- Resistance to the Proteasome Inhibitors: Lessons from Multiple Myeloma and Mantle Cell Lymphoma -- Part II. Neurodegeneration -- Altered Proteostasis in Neurodegenerative Tauopathies -- The Ubiquitin System in Alzheimer’s Disease -- The Interplay Between Proteostasis Systems and Parkinson’s Disease -- Machado–Joseph Disease: A Stress Combating Deubiquitylating Enzyme Changing Sides -- Part III. Infection, Inflammation and Developmental Disorders -- SUMO and Cytoplasmic RNA Viruses: From Enemies to Best Friends -- The Role of Proteostasis in the Regulation of Cardiac Intercellular Communication -- By the Tips of Your Cilia: Ciliogenesis in the Retina and the Ubiquitin-Proteasome System -- TRIM E3 Ubiquitin Ligases in Rare Genetic Disorders -- Part IV. Diet -- We Are What We Eat: Ubiquitin–Proteasome System (UPS) Modulation Through Dietary Products.
    Abstract: This book, written by members of the European network PROTEOSTASIS, provides an up-to-date review of the research regarding protein homeostasis in health and disease. With new discoveries contributing to the increasing complexity of this topic, the book offers a detailed overview of the pathways regulating protein homeostasis, including autophagy and the ubiquitin protein family. Following a basic introduction, it explains how defects in protein homeostasis contribute to numerous pathologies, including cancer, neurodegeneration, inflammation and a number of rare diseases. In addition, it discusses, the role of protein homeostasis in cellular development and physiology. Highlighting the latest research in the field of protein homeostasis and its implications for various clinically relevant diseases, the book appeals to researchers and clinicians, while also offering a reference guide for scholars who are new to the field.
    Type of Medium: Online Resource
    Pages: XII, 348 p. 42 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030382667
    Series Statement: Advances in Experimental Medicine and Biology, 1233
    URL: https://doi.org/10.1007/978-3-030-38266-7
    DOI: 10.1007/978-3-030-38266-7
    DDC: 571.6
    Language: English
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  • 3
    Online Resource
    Online Resource
    Cell Biology and Translational Medicine, Volume 16 : Stem Cells in Tissue Regeneration, Therapy and Drug Discovery (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Cytology. ; Stem cells. ; Medicine Research. ; Biology Research. ; Neurosciences. ; Cancer. ; Cell Biology. ; Stem Cell Biology. ; Translational Research. ; Neuroscience. ; Cancer Biology.
    Description / Table of Contents: Epithelial Stem Cells: Making, Shaping and Breaking the Niche -- Parathyroid Cell Differentiation from Progenitor Cells and Stem Cells: Development, Molecular Mechanism, Function, and Tissue Engineering -- Regenerative Medicine Application of Mesenchymal Stem -- Identification of Small Molecules That Enhance the Expansion of Mesenchymal Stem Cells Originating from Bone Marrow -- Human-Induced Pluripotent Stem Cell-Based Models for Studying Sex-Specific Differences in Neurodegenerative Diseases -- Current Status, Barriers, and Future Directions for Humanized Mouse Models to Evaluate Stem Cell-Based Islet Cell Transplant -- Mesenchymal Stem Cell Therapy for Osteoarthritis: Practice and Possible Promises -- The Historical Relationship Between Meis1 and Leukemia -- An Overview of Zebrafish Modeling Methods in Drug Discovery and Development -- Cellular Stress Responses in Oocytes: Molecular Changes and Clinical Implications.
    Abstract: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of Springer Nature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the 16th volume of a continuing series. Chapter "Epithelial Stem Cells: Making, Shaping and Breaking the Niche" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 193 p. 29 illus., 19 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031106385
    Series Statement: Cell Biology and Translational Medicine, 1387
    URL: https://doi.org/10.1007/978-3-031-10638-5
    DOI: 10.1007/978-3-031-10638-5
    DDC: 571.6
    Language: English
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  • 4
    Online Resource
    Online Resource
    Cell Biology and Translational Medicine, Volume 19 : Perspectives in Diverse Human Diseases and Their Therapeutic Options (2023)
    Cham :Springer Nature Switzerland :
    Details
    Keywords: Cytology. ; Virology. ; Neurosciences. ; Cancer. ; Stem cells. ; Sports medicine. ; Cell Biology. ; Virology. ; Neuroscience. ; Cancer Biology. ; Stem Cell Biology. ; Sports Medicine.
    Description / Table of Contents: Monkeypox and Sexually Transmitted Diseases -- Clinical Manifestations of Monkeypox -- Laboratory Diagnosis for Monkeypox: Clinical Practice and Important Points to Be Recognized -- Regulatory Mechanisms of Muscle Mass: The Critical Role of Resistance Training in Children and Adolescent -- HSF1 and Its Role in Huntington's Disease Pathology -- Leveraging Tissue Engineering for Skin Cancer Models -- Application of Drug Repurposing-Based Precision Medicine Platform for Leukaemia Patient Treatment -- Stem Cell-Derived Extracellular Vesicles as a Potential Therapeutic Tool for Eye Diseases: From Benchtop to Bedside -- Cannabinoids as Prospective Anti-Cancer Drugs: Mechanism of Action in Healthy and Cancer Cells -- Direct Reprogramming of Somatic Cells into Induced β-Cells: An Overview.
    Abstract: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of Springer Nature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the 19th volume of a continuing series.
    Type of Medium: Online Resource
    Pages: VIII, 194 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031284205
    Series Statement: Cell Biology and Translational Medicine, 1410
    URL: https://doi.org/10.1007/978-3-031-28420-5
    DOI: 10.1007/978-3-031-28420-5
    DDC: 571.6
    Language: English
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  • 5
    Online Resource
    Online Resource
    Electrical Properties of Tissues : Quantitative Magnetic Resonance Mapping (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotechnology. ; Radiology. ; Biomedical engineering. ; Neurosciences. ; Biotechnology. ; Radiology. ; Biomedical Engineering and Bioengineering. ; Neuroscience.
    Description / Table of Contents: Electromagnetic Properties and the Basis for CDI, MREIT and EPT -- Modeling for Electromagnetic Characterization, Prediction and Reconstruction -- Magnetic Resonance Imaging Basics -- Phantom Construction and Equipment Configurations for Characterizing Electrical Properties using MRI -- MR Current Density and MREIT Data Acquisition -- Magnetic Resonance Current Density Imaging (MR-CDI) -- Magnetic Resonance Electrical Impedance Tomography -- Index.
    Abstract: This book covers the latest developments in tissue electrical conductivity and current density imaging, increasingly popular as well as challenging applications of MRI. These applications are enabled by the acquisition of high-quality MR phase images. This book provides a practical description of the MRI physics needed to understand and acquire phase images in MRI and the key details required to reconstruct them into conductivity, current density or electric field distributions. Comprehensive details are provided about the electrical properties of biological tissues, computational modeling considerations, experimental methods, construction of non-biological and biological phantoms and MRI pulse sequences. An inclusive review of image reconstruction algorithms, and their potential applications is provided for applications directed at determining current density or electric fields, such as in transcranial DC or AC stimulation techniques; as well as electrical conductivity reconstructions that may be of use in quantitative MRI applications used to detect cancer or other pathologies. This is an excellent book for undergraduate and graduate students beginning to explore phase, current density, and conductivity imaging in MRI, and will also be of great use to researchers interested in the area of MR-based electrical property imaging.
    Type of Medium: Online Resource
    Pages: VII, 206 p. 101 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031038730
    Series Statement: Advances in Experimental Medicine and Biology, 1380
    URL: https://doi.org/10.1007/978-3-031-03873-0
    DOI: 10.1007/978-3-031-03873-0
    DDC: 660.6
    Language: English
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  • 6
    Online Resource
    Online Resource
    Bioinspired Biomaterials : Advances in Tissue Engineering and Regenerative Medicine (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Biotechnology. ; Regenerative medicine. ; Pharmaceutical chemistry. ; Neurosciences. ; Biotechnology. ; Regenerative Medicine and Tissue Engineering. ; Pharmaceutics. ; Neuroscience. ; Chemical Bioengineering.
    Description / Table of Contents: Part I. Novel Bioinspired Biomaterials for Regenerative Medicine -- Chapter 1. Natural Sources and Applications of Demineralized Bone Matrix in the Field of Bone and Cartilage Tissue Engineering -- Chapter 2. Application of Gellan Gum-based Scaffold for Regenerative Medicine -- Chapter 3. Natural Fibrous Protein for Advanced Tissue Engineering Applications: Focusing on Silk Fibroin and Keratin -- Part II. Bioinspired 3D Bioprinting Hydrogel for Regenerative Medicine -- Chapter 4. Silk Fibroin Bioinks for Digital Light Processing (DLP) 3D Bioprinting -- Chapter 5. 3D-Bioprinting of Tissue Models with Customized Bioinks -- Chapter 6. Visible Light-curable Hydrogel Systems for Tissue Engineering and Drug Delivery -- Part III. Regulation of Stem Cell Fate by Bioinspired Biomaterials -- Chapter 7. Scaffolds for Cartilage Regeneration: To Use or Not to Use -- Chapter 8. Bio-application of Inorganic Nanomaterials in Tissue Engineering -- Chapter 9. Directional Cell Migration Guide for Improved Tissue Regeneration -- Part IV. Cutting-Edge Enabling Technology for Regenerative Medicine -- Chapter 10. Extracellular Vesicles: The Next Frontier in Regenerative Medicine and Drug Delivery -- Chapter 11. Application of Tissue Engineering and Regenerative Medicine in Maternal-fetal Medicine -- Chapter 12. Fundamentals and Current Strategies for Peripheral Nerve Repair and Regeneration -- Chapter 13. Protein-based Drug Delivery in Brain Tumor Therapy -- Chapter 14. Human Hair: Scaffold Materials for Regenerative Medicine.
    Abstract: This book is the first of two volumes that together offer a comprehensive account of cutting-edge advances in the development of biomaterials for use within tissue engineering and regenerative medicine. Topics addressed in this volume, which is devoted to bioinspired biomaterials, range from novel biomaterials for regenerative medicine through to emerging enabling technologies with applications in, for example, drug delivery, maternal–fetal medicine, peripheral nerve repair and regeneration, and brain tumor therapy. New bioinspired hydrogels receive detailed attention in the book, and a further focus is the use of bioinspired biomaterials in the regulation of stem cell fate. Here the coverage includes the role of scaffolds in cartilage regeneration, the bioapplication of inorganic nanomaterials in tissue engineering, and guidance of cell migration to improve tissue regeneration. The authors are recognized experts in the interdisciplinary field of regenerative medicine and the book will be of value for all with an interest in regenerative medicine based on biomaterials. .
    Type of Medium: Online Resource
    Pages: X, 229 p. 45 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811532580
    Series Statement: Advances in Experimental Medicine and Biology, 1249
    URL: https://doi.org/10.1007/978-981-15-3258-0
    DOI: 10.1007/978-981-15-3258-0
    DDC: 660.6
    Language: English
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  • 7
    Online Resource
    Online Resource
    Biomimicked Biomaterials : Advances in Tissue Engineering and Regenerative Medicine (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Biotechnology. ; Regenerative medicine. ; Pharmaceutical chemistry. ; Neurosciences. ; Biotechnology. ; Regenerative Medicine and Tissue Engineering. ; Pharmaceutics. ; Neuroscience. ; Chemical Bioengineering.
    Description / Table of Contents: Part I. Novel Biomimicked Biomaterials for Regenerative Medicine -- Chapter 1. Bone Regeneration using Duck’s Feet Derived Collagen Scaffold as an Alternative Collagen Source -- Chapter 2. Decellularized Extracellular Matrices for Tissue Engineering and Regeneration -- Part II. Novel Biomimicked Hydrogel for Regenerative Medicine -- Chapter 3. Injectable in situ-forming Hydrogels for Protein and Peptide Delivery -- Chapter 4. Alginate Hydrogels as 3D Cell Encapsulation Matrices for Tissue Engineering and Regenerative Medicine -- Chapter 5. Design of Advanced Polymeric Hydrogels for Tissue Regenerative Medicine: Oxygen-controllable Hydrogel Materials -- Chapter 6. Enhancing Osteochondral Tissue Regeneration of Gellan Gum by Incorporating Gallus Gallus var Domesticus Derived Demineralized Bone Particle -- Part III. Control of Stem Cell Fate by Biomaterials for Regenerative Medicine -- Chapter 7. The Development of Extracellular Vesicles-Integrated Biomaterials for Bone Regeneration -- Chapter 8. In vivo Evaluation of the Biocompatibility of Biomaterial Device -- Chapter 9. Cell Response to Materials for Biomedical Engineering -- Chapter 10. Regulation of Stem Cell Functions by Micro-patterned Structures -- Part IV. Nano-Intelligent Biocomposites for Regenerative Medicine -- Chapter 11. Natural Polyphenols as Modulators of the Fibrillization of Islet Amyloid Polypeptide -- Chapter 12.Recent Advances of Biphasic Calcium Phosphate Bioceramics for Bone Tissue Regeneration -- Chapter 13. Surface-modifying Polymers for Blood-Contacting Polymeric Biomaterials.
    Abstract: This book is the second of two volumes that together offer a comprehensive account of cutting-edge advances in the development of biomaterials for use within tissue engineering and regenerative medicine. In this volume, which is devoted to biomimetic biomaterials, the opening section discusses bone regeneration by means of duck’s feet-derived collagen scaffold and the use of decellularized extracellular matrices. The role of various novel biomimetic hydrogels in regenerative medicine is then considered in detail. The third section focuses on the control of stem cell fate by biomimetic biomaterials, covering exosome-integrated biomaterials for bone regeneration, cellular responses to materials for biomedical engineering, and the regulation of stem cell functions by micropatterned structures. Finally, the use of nano-intelligent biocomposites in regenerative medicine is addressed, with discussion of, for example, recent advances in biphasic calcium phosphate bioceramics and blood-contacting polymeric biomaterials. The authors are recognized experts in the interdisciplinary field of regenerative medicine and the book will be of value for all with an interest in regenerative medicine based on biomaterials.
    Type of Medium: Online Resource
    Pages: X, 198 p. 60 illus., 58 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811532627
    Series Statement: Advances in Experimental Medicine and Biology, 1250
    URL: https://doi.org/10.1007/978-981-15-3262-7
    DOI: 10.1007/978-981-15-3262-7
    DDC: 660.6
    Language: English
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  • 8
    Online Resource
    Online Resource
    Role of Oxidative Stress in Pathophysiology of Diseases (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Cytology. ; Stress (Physiology). ; Human physiology. ; Cancer. ; Diseases. ; Neurosciences. ; Nanotechnology. ; Cellular Stress. ; Human Physiology. ; Cancer Biology. ; Diseases. ; Neuroscience. ; Nanotechnology.
    Description / Table of Contents: Chapter 1. Oxidative stress and oral diseases -- Chapter 2. Role of Oxidative stress in Chronic Liver Diseases -- Chapter 3. In-vitro and In-vivo Antioxidant activity of nanoparticles -- Chapter 4. Oxidative stress in neurology and neurodegenerative processes -- Chapter 5. The role of oxidative stress in respiratory diseases -- Chapter 6. Role of Synbiotics in alleviating oxidative stress in colorectal cancer -- Chapter 7. Oxidative Stress and Immunological Complexities in Multi-Drug Resistant Tuberculosis -- Chapter 8. Infection-induced Oxidative Stress in Chronic Respiratory Diseases -- Chapter 9. Oxidative stress in neuropsychiatric and neurodegenerative diseases -- Chapter 10. Oxidative stress monitoring in in vitro and in vivo models -- Chapter 11. Effects of Yoga on Aging.
    Abstract: This book illustrates the importance and significance of oxidative stress in the pathophysiology of various human diseases. The book initially introduces the phenomenon of oxidative stress, basic chemical characteristics of the species involved and summarizes the cellular oxidant and anti-oxidant system and the cellular effects and metabolism of the oxidative stress. In addition, it reviews the current understanding of the potential impact of oxidative stress on telomere shortening, aging, and age-related diseases. It also examines the role of oxidative stress in chronic diseases, including cancer, diabetes, cardiovascular diseases, and neurodegenerative disorders. Further, the book presents novel technologies for the detection of oxidative stress biomarkers using nanostructure biosensors, as well as in vitro and in vivo models to monitor oxidative stress. Lastly, the book addresses the drug delivery carriers that can help in combating oxidative stress.
    Type of Medium: Online Resource
    Pages: X, 297 p. 48 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811515682
    URL: https://doi.org/10.1007/978-981-15-1568-2
    DOI: 10.1007/978-981-15-1568-2
    DDC: 571.6
    Language: English
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  • 9
    Online Resource
    Online Resource
    Stem Cell-based Therapy for Neurodegenerative Diseases (2020)
    Singapore :Springer Nature Singapore :
    Details
    Keywords: Stem cells. ; Neurosciences. ; Neurology . ; Stem Cell Biology. ; Neuroscience. ; Neurology.
    Description / Table of Contents: Chapter 1: General Introduction -- Chapter 2: Clinical-grade stem cells for the treatment of neurodegenerative diseases -- Chapter 3: Stem cell treatment for Parkinson's disease -- Chapter 4: Stem cell treatment for Alzheimer's disease -- Chapter 5: Stem cell treatment for Huntington’s disease -- Chapter 6: Stem cell treatment for amyotrophic sclerosis disease -- Chapter 7: Stem cell treatment for multiple sclerosis -- Chapter 8: Stem cell treatment for muscular dystrophy -- Chapter 9: Stem cell treatment for spinal muscular atrophy -- Chapter 10: Stem cell treatment for Retinal Degeneration -- Chapter 11: Conclusion and future perspective.
    Abstract: This book reviews the state-of-the-art in stem-cell-based therapies for neurodegenerative diseases, and highlights advances in both animal models and clinical trials. It comprehensively discusses most neurodegenerative diseases, including such as Parkinson's, Alzheimer's and Huntington’s diseases, amyotrophic sclerosis, multiple sclerosis, muscular dystrophy and retinal degeneration, in which stem cells could potentially be used for therapy in the future. It also addresses the challenges and problems relating to the translation of stem-cell-based therapies into treatments. As such, the book will appeal to research scientists, physicians, graduate students, and medical professionals in the field of stem cells, neuroscience, neurology, neurorestoratology and major neurological disorders.
    Type of Medium: Online Resource
    Pages: V, 145 p. 20 illus., 19 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811543708
    Series Statement: Advances in Experimental Medicine and Biology, 1266
    URL: https://doi.org/10.1007/978-981-15-4370-8
    DOI: 10.1007/978-981-15-4370-8
    DDC: 571.6
    Language: English
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  • 10
    Online Resource
    Online Resource
    Engineering Biomaterials for Neural Applications : Targeting Traumatic Brain and Spinal Cord Injuries (2022)
    Cham :Springer International Publishing :
    Details
    Keywords: Biotechnology. ; Neurosciences. ; Biomaterials. ; Biotechnology. ; Neuroscience. ; Biomaterials.
    Description / Table of Contents: General aspects of neural diseases and requirements of CNS implantable biomaterials as diagnostic and/or therapeutic tools -- Characteristics of the traumatic brain and spinal cord injured patients as a host of a CNS implanted biomaterial -- Electrophysiological recording at the damaged neural tissue -- Mechanical aspects of biomaterials and neural tissues -- Nanostructures to potentiate axon navigation and regrowth in CNS damaged tissue.-Electrical stimulation-based approaches focused on electrodes -- Engineered 2D and 3D biomaterials for neural applications -- Magnetic nanoparticles for the treatment of neural pathologies -- Magnetic devices for sensing at the neural tissue -- Cell therapies for neural applications -- Basics on electrical modeling of the electrode/tissue interface -- CNS therapeutic approaches in implantable devices for neurological diseases -- Index.
    Abstract: This book describes past and present advances in engineering materials for neural applications, with special emphasis on their usefulness for traumatic brain and spinal cord injuries. The book presents major physio-pathological features of traumatic injuries at the brain and spinal cord as examples of diseases hampering the central nervous tissue. By incorporating knowledge from the perspective of experts with diverse backgrounds, this book gives insight into the understanding of these multifaceted pathologies and the materials science approaches that aim to cure them. The interdisciplinary nature of this book makes it a perfect candidate for the interest of a broad audience, from clinicians working on neural diseases to scientists whose work focuses on the nervous tissue (neuroscientists) and/or materials science. Undergraduate and PhD students can also benefit from the knowledge and discussion included in this book.
    Type of Medium: Online Resource
    Pages: XXVI, 310 p. 77 illus., 73 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030814007
    URL: https://doi.org/10.1007/978-3-030-81400-7
    DOI: 10.1007/978-3-030-81400-7
    DDC: 660.6
    Language: English
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