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Neurosecretion: Secretory Mechanisms (2020)

Lemos, José R. [editor.] ; Dayanithi, Govindan. [editor.]

Cham :Springer International Publishing :

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Schlagwort(e): Neurosciences. ; Anatomy. ; Internal medicine. ; Cytology. ; Biochemistry. ; Neuroscience. ; Anatomy. ; Internal Medicine. ; Cell Biology. ; Biochemistry.

Beschreibung / Inhaltsverzeichnis: Neurosecretion: A Historical Overview -- Neurosecretion: Hypothalamic Somata versus Neurohypophysial Terminals -- Cyclic ADP-Ribose and Heat Regulate Oxytocin Release via CD38 and TRPM2 in the Hypothalamus -- Somato-Dendritic Secretion of Neuropeptides -- Neurosecretory Vesicles: Structure, Distribution, Release and Breakdown -- Molecular Controls on Regulated Neurotransmitter and Neurohormone Secretion -- Secretory Astrocytes -- Action Potential-Induced Ca2+ Influx for Both Acute and Sustained Insulin Secretion in Pancreatic Beta Cells -- Plasticity in the Morphology of Lactotrophs and Folliculo-Stellate Cells and Prolactin Secretion -- Neuroendocrine and Metabolic Regulation of Plasma Growth Hormone Secretory Profiles -- Role of the TWIK-Related Potassium (TREK)-1 Channels in the Regulation of Adrenocorticotropic Hormone (ACTH) Secretion from Pituitary Corticotropes -- How Do Bacterial Neurotoxins Affect Neurosecretion? -- Secretory Mechanisms in Paramecium.

Kurzfassung: How do electrical activity and calcium signals in neurons influence the secretion of peptide hormones? This volume presents the current state of knowledge regarding the electrical, calcium signaling and synaptic properties of neuroendocrine systems from both vertebrate and invertebrate systems. The contributions span in vivo and in vitro studies that address: state‐dependent plasticity, relevance of firing patterns, membrane properties, calcium flux (including dynamic imaging and homeostasis), and molecular mechanisms of exocytosis, including from non-neuronal secretory cells. The chapters focus not only on research results but also on how experiments are conducted using state-of-the-art techniques, and how the resulting data are interpreted. While there are many books on the secretory properties of neurons, this is the first to focus on the distinctive secretory properties of neuroendocrine neurons. Accordingly, it offers an important text for undergraduate and graduate neuroscience students, and will also appeal to established scientists and postdoctoral fellows. This is the eighth volume in the Masterclass in Neuroendocrinology series* - now a co-publication between Springer Nature and the INF (International Neuroendocrine Federation). *Volumes 1-7 published by Wiley.

Materialart: Online-Ressource

Seiten: XIII, 307 p. 65 illus., 43 illus. in color. , online resource.

Ausgabe: 1st ed. 2020.

ISBN: 9783030229894

Serie: Masterclass in Neuroendocrinology, 8

URL: https://doi.org/10.1007/978-3-030-22989-4

DOI: 10.1007/978-3-030-22989-4

DDC: 612.8

Sprache: Englisch

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The Secret Lives of Transcription Factors : In Heterochromatin Regulation (2023)

Li, Willis X. ; Silver-Morse, Louise.

Cham :Springer International Publishing :

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Schlagwort(e): Cytology. ; Physiology. ; Medical genetics. ; Cell Biology. ; Physiology. ; Medical Genetics.

Beschreibung / Inhaltsverzeichnis: Chapter 1 Introduction -- Chapter 2 Unconventional functions of transcription factors -- GAGA transcription factor -- Heterochromatin protein 1 -- Retinoblastoma protein -- STAT -- ATF-2 -- NF-kB -- Chapter 3 STAT and HP1, in their unconventional roles, promote longevity and protect against DNA damage and cancer -- STAT and HP1 promote longevity -- STAT and HP1 protect against DNA damage -- Increased levels of STAT and HP1 hinder carcinogenesis in a mouse xenograft model -- Chapter 4 The possible biological significance of transcription factors’ unconventional functions -- The epigenome -- Processes in the cell nucleus -- Future Work.

Kurzfassung: This SpringerBrief explores unconventional functions of eight different transcription factors and concludes with a discussion of their biological significance and impact, including effects on processes within the cell nucleaus during development and in adult organisms. Chapter One details unconventional functions of the transcription factors GAGA, HP1, Rb, STAT, ATF-2 and NF-kB. Surprisingly, all of these transcription factors can be found in association with heterochromatin as well as euchromatin, and in some cases unconventional functions have been demonstrated for these heterochromatin-associated factors. Chapter Two focuses on the unconventional functions of STAT and HP1 and discusses their roles in the promotion of longevity, and in protection from cancer and DNA damage. Chapter Three explores the biological significance of the findings presented in the first two chapters and considers how global changes in the epigenome brought about by factors such as STAT and HP1 might affect processes within the cell nucleus during development and in adult organisms. This succinct yet thorough SpringerBrief is essential for researchers studying epigenetics, and to instructors of the subject. It should also appeal to people interested in the control of gene transcription and other processes in the cell nucleus, and to those interested in development.

Materialart: Online-Ressource

Seiten: VI, 45 p. 6 illus., 5 illus. in color. , online resource.

Ausgabe: 1st ed. 2023.

ISBN: 9783031290299

Serie: SpringerBriefs in Biochemistry and Molecular Biology,

URL: https://doi.org/10.1007/978-3-031-29029-9

DOI: 10.1007/978-3-031-29029-9

DDC: 571.6

Sprache: Englisch

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Molecular Biochemical Aspects of Cancer (2020)

Das, Undurti N.

New York, NY :Springer US :

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Schlagwort(e): Cytology. ; Cancer. ; Medicine Research. ; Biology Research. ; Cell Biology. ; Cancer Biology. ; Biomedical Research.

Beschreibung / Inhaltsverzeichnis: Introduction to genes, oncogenes, and anti-oncogenes -- Introduction to free radicals (including nitric oxide), antioxidants, lipid peroxidation and their effects on cell proliferation -- Immune system, inflammation and essential fatty acids and their metabolites in cancer -- PUFAs and their metabolites in carcinogenesis -- Molecular mechanism of anti-cancer action of PUFAs with particular reference to GLA in glioma -- Bioactive lipids (BAL)-based therapeutic approach to cancer that enhances anti-tumor action and ameliorates cytokine release syndrome of immune check point inhibitors -- A new therapeutic strategy to treat cancer based on bioactive lipids (BAL) -- Index.

Kurzfassung: This book discusses the role of genes, oncogenes, anti-oncogenes, free radicals, PUFAs, anti-oxidants, lipid peroxidation process, telomere, and angiogenesis on the origin of cancer, cell proliferation, and cancer in general. It includes a broad introduction to cancer cells; genes, oncogenes, and anti-oncogenes; and free radicals. In later chapters, it discusses in depth the relationship among free radicals, lipid peroxidation and anti-oxidants in cell proliferation. It also discusses aerobic and anaerobic metabolism and their relationship to cancer, as well as the Warburg effect and its potential in the development of new targets for cancer management. Based on these and other evidences, Molecular Biochemical Aspects of Cancer introduces a novel concept that suggests that selective enhancement of free radical generation in tumor cells could form a strategy to induce apoptosis of cancer cells employing bioactive lipids. It presents a new method of treatment of cancer using in vitro, in vivo and clinical data. This book will interest oncologists, scientists, molecular biologists, life scientists.

Materialart: Online-Ressource

Seiten: XIII, 254 p. 58 illus., 42 illus. in color. , online resource.

Ausgabe: 1st ed. 2020.

ISBN: 9781071607411

URL: https://doi.org/10.1007/978-1-0716-0741-1

DOI: 10.1007/978-1-0716-0741-1

DDC: 571.6

Sprache: Englisch

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Bioimage Data Analysis Workflows ‒ Advanced Components and Methods (2022)

Miura, Kota. [editor.] ; Sladoje, Nataša. [editor.]

Cham :Springer International Publishing :

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Schlagwort(e): Cytology. ; Bioinformatics. ; Imaging systems in biology. ; Cell Biology. ; Computational and Systems Biology. ; Biological Imaging.

Beschreibung / Inhaltsverzeichnis: Introduction -- Batch Processing Methods in ImageJ -- Python: Data Handling, Analysis and Plotting -- Building a Bioimage Analysis Workflow Using Deep Learning -- GPU-Accelerating ImageJ Macro Image Processing Workflows Using CLIJ -- How to Do the Deconstruction of Bioimage Analysis Workflows: A Case Study with SurfCut -- i.2.i. with the (Fruit) Fly: Quantifying Position Effect Variegation in Drosophila Melanogaster -- A MATLAB Pipeline for Spatiotemporal Quantification of Monolayer Cell Migration.

Kurzfassung: This open access textbook aims at providing detailed explanations on how to design and construct image analysis workflows to successfully conduct bioimage analysis. Addressing the main challenges in image data analysis, where acquisition by powerful imaging devices results in very large amounts of collected image data, the book discusses techniques relying on batch and GPU programming, as well as on powerful deep learning-based algorithms. In addition, downstream data processing techniques are introduced, such as Python libraries for data organization, plotting, and visualizations. Finally, by studying the way individual unique ideas are implemented in the workflows, readers are carefully guided through how the parameters driving biological systems are revealed by analyzing image data. These studies include segmentation of plant tissue epidermis, analysis of the spatial pattern of the eye development in fruit flies, and the analysis of collective cell migration dynamics. The presented content extends the Bioimage Data Analysis Workflows textbook (Miura, Sladoje, 2020), published in this same series, with new contributions and advanced material, while preserving the well-appreciated pedagogical approach adopted and promoted during the training schools for bioimage analysis organized within NEUBIAS – the Network of European Bioimage Analysts. This textbook is intended for advanced students in various fields of the life sciences and biomedicine, as well as staff scientists and faculty members who conduct regular quantitative analyses of microscopy images.

Materialart: Online-Ressource

Seiten: X, 212 p. 265 illus. in color. , online resource.

Ausgabe: 1st ed. 2022.

ISBN: 9783030763947

Serie: Learning Materials in Biosciences,

URL: https://doi.org/10.1007/978-3-030-76394-7

DOI: 10.1007/978-3-030-76394-7

DDC: 571.6

Sprache: Englisch

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Pigments, Pigment Cells and Pigment Patterns (2021)

Hashimoto, Hisashi. [editor.] ; Goda, Makoto. [editor.] ; Futahashi, Ryo. [editor.] ; [weitere]

Singapore :Springer Nature Singapore :

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Schlagwort(e): Cytology. ; Developmental biology. ; Zoology. ; Biochemistry. ; Evolution (Biology). ; Psychobiology. ; Human behavior. ; Cell Biology. ; Developmental Biology and Stem Cells. ; Zoology. ; Chemical Biology. ; Evolutionary Biology. ; Behavioral Neuroscience.

Beschreibung / Inhaltsverzeichnis: Part 1 Pigments and pigment organelles -- 1 Pigments in insects -- 2 Melanins in vertebrates -- 3 Body color expression in birds -- 4 Pigments in teleosts and their biosynthesis -- 5 Bioluminescence and Pigments -- Part 2 Pigment cell and patterned pigmentation -- 6 Development of melanin-bearing pigment cells in birds and mammals -- 7 Pigment cell development in teleosts -- 8 Pigment patterning in teleosts -- 9 Theoretical studies of pigment pattern formation -- 10 Evolution of Pigment Pattern Formation in Teleosts -- 11 Mechanisms of feather structural coloration and pattern formation in birds -- 12 Mechanism of color pattern formation in insects -- Part 3 Color changes -- 13 Physiological and Morphological Color Changes in Teleosts and in Reptiles -- 14 Color change in cephalopods -- 15 Physiological and biochemical mechanisms of insect color change towards understanding molecular links.

Kurzfassung: This book comprehensively summarizes the biological mechanisms of coloration and pattern formation of animals at molecular and cellular level, offering up-to-date knowledge derived from remarkable progress in the last 10 years. The brilliant coloration, conspicuous patterns and spectacular color changes displayed by some vertebrates and invertebrates are generally their strategies of the utmost importance for survival. Consists of mainly three parts, starts with introductory chapter, such as Pigments and Pigment Organelles, Developmental Genetics of Pigment Cell Formation, Adult Pigment Patterns, and Color Changes, this book introduces new pigment compounds in addition to classically known pigments and organelles, explains how the generation of multiple types of pigment cell is genetically controlled, describes the mechanisms underlying the zebrafish stripe formation as well as other animals and also summarizes the mechanism of physiological and morphological color changes of teleost, amphibian and cephalopod. Written by experts in the field, this book will be essential reading for graduate students and researchers in biological fields who are interested in pigmentation mechanisms of animals.

Materialart: Online-Ressource

Seiten: XII, 472 p. 192 illus., 153 illus. in color. , online resource.

Ausgabe: 1st ed. 2021.

ISBN: 9789811614903

URL: https://doi.org/10.1007/978-981-16-1490-3

DOI: 10.1007/978-981-16-1490-3

DDC: 571.6

Sprache: Englisch

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Cell Biology and Translational Medicine, Volume 10 : Stem Cells in Tissue Regeneration (2020)

Turksen, Kursad. [editor.]

Cham :Springer International Publishing :

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Schlagwort(e): Cytology. ; Cell Biology.

Beschreibung / Inhaltsverzeichnis: Apelin Receptor Signaling During Mesoderm Development -- Epidermal stem cells in regenerative medicine -- The cellular and molecular patterns involved in the neural differentiation of adipose-derived stem cells -- Biomatrices for heart regeneration and cardiac tissue modelling in vitro -- Dentin-Pulp Tissue Regeneration Approaches in Dentistry: An Overview and Current Trends -- Stem Cell Culture under Simulated Microgravity -- Smart Polymeric Systems: A Biomedical Viewpoint -- Acute lung injury: Disease modelling and the therapeutic potential of stem cells -- COVID-19 and Mesenchymal Stem Cell Treatment; Mystery or Not -- PCDH19 pathogenic variants in males: Expanding the phenotypic spectrum.

Kurzfassung: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the tenth volume of a continuing series.

Materialart: Online-Ressource

Seiten: VII, 191 p. 1 illus. , online resource.

Ausgabe: 1st ed. 2020.

ISBN: 9783030600129

Serie: Cell Biology and Translational Medicine, 1298

URL: https://doi.org/10.1007/978-3-030-60012-9

DOI: 10.1007/978-3-030-60012-9

DDC: 571.6

Sprache: Englisch

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Tight Junctions (2022)

González-Mariscal, Lorenza. [editor.]

Cham :Springer International Publishing :

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Schlagwort(e): Cytology. ; Neurosciences. ; Medicine Research. ; Biology Research. ; Pharmacology. ; Cell Biology. ; Neuroscience. ; Biomedical Research. ; Pharmacology.

Beschreibung / Inhaltsverzeichnis: A historical and evolutionary view of tight junctions -- Tricellular tight junctions -- Mechanosensitivity of tight junctions -- Intracellular traffic and non-canonical roles of ZO-2 protein -- Impact of claudin-2 and occludin expression in inflammation disorders -- Tight junctions in the inflamed gut -- Intestinal barrier disruption by enteropathogenic Escherichia coli -- Tight junction barrier function regulation by microbiota -- Claudin-7 participation in cell-substrate adhesion, cell migration, salt balance in the renal collecting duct and gut cell renewal and differentiation -- Regulation of the alveolar epithelial barrier by claudin-5 -- Regulation of the blood-retinal barrier by occludin phosphorylation, norrin and sonic hedgehog signaling -- Transmigration of metastatic cells through the blood-brain barrier -- Endocytosis of tight junction proteins -- Regulated degradation of claudins. .

Kurzfassung: This volume explores the dynamic topic of tight junctions. The book focuses on tight junctions' role in sealing adjacent epithelial cells in a narrow band just beneath their apical surface. The book explains how tight junctions consist of a network of claudins and other proteins, and delves into how they hold cells together and form functional and protective barriers, regulating the passage of molecules and ions through the space between cells. The book opens with a discussion of the evolution of research on tight junctions, discussing a range of primary areas of growth, including the current knowledge on the particular physiological function of different claudins due to the development of an array of knock out mice. The chapters also explore in-depth studies of tight junctions in specific tissues (gut, lung and endothelia). This book offers a comprehensive understanding on post-translational modifications of occludin and its impact on tight junction function, as well as the molecular composition and function of tricellular tight junctions. This volume is particularly relevant to students and scientists in neuroscience, cell biology, physiology, cell differentiation, and cancer research.

Materialart: Online-Ressource

Seiten: XII, 334 p. 47 illus., 44 illus. in color. , online resource.

Ausgabe: 1st ed. 2022.

ISBN: 9783030972042

URL: https://doi.org/10.1007/978-3-030-97204-2

DOI: 10.1007/978-3-030-97204-2

DDC: 571.6

Sprache: Englisch

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Proteostasis and Disease : From Basic Mechanisms to Clinics (2020)

Barrio, Rosa. [editor.] ; Sutherland, James D. [editor.] ; Rodriguez, Manuel S. [editor.]

Cham :Springer International Publishing :

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Schlagwort(e): Cytology. ; Neurosciences. ; Immunology. ; Medicine Research. ; Biology Research. ; Cancer. ; Cell Biology. ; Neuroscience. ; Immunology. ; Biomedical Research. ; Cancer Biology.

Beschreibung / Inhaltsverzeichnis: Part I. Cancer -- Ubiquitin-Regulated Cell Proliferation and Cancer -- Ubiquitin, SUMO, and Nedd8 as Therapeutic Targets in Cancer -- The Proteasome System in Health and Disease -- Proteostasis Dysregulation in Pancreatic Cancer -- Divergent Modulation of Proteostasis in Prostate Cancer -- Resistance to the Proteasome Inhibitors: Lessons from Multiple Myeloma and Mantle Cell Lymphoma -- Part II. Neurodegeneration -- Altered Proteostasis in Neurodegenerative Tauopathies -- The Ubiquitin System in Alzheimer’s Disease -- The Interplay Between Proteostasis Systems and Parkinson’s Disease -- Machado–Joseph Disease: A Stress Combating Deubiquitylating Enzyme Changing Sides -- Part III. Infection, Inﬂammation and Developmental Disorders -- SUMO and Cytoplasmic RNA Viruses: From Enemies to Best Friends -- The Role of Proteostasis in the Regulation of Cardiac Intercellular Communication -- By the Tips of Your Cilia: Ciliogenesis in the Retina and the Ubiquitin-Proteasome System -- TRIM E3 Ubiquitin Ligases in Rare Genetic Disorders -- Part IV. Diet -- We Are What We Eat: Ubiquitin–Proteasome System (UPS) Modulation Through Dietary Products.

Kurzfassung: This book, written by members of the European network PROTEOSTASIS, provides an up-to-date review of the research regarding protein homeostasis in health and disease. With new discoveries contributing to the increasing complexity of this topic, the book offers a detailed overview of the pathways regulating protein homeostasis, including autophagy and the ubiquitin protein family. Following a basic introduction, it explains how defects in protein homeostasis contribute to numerous pathologies, including cancer, neurodegeneration, inflammation and a number of rare diseases. In addition, it discusses, the role of protein homeostasis in cellular development and physiology. Highlighting the latest research in the field of protein homeostasis and its implications for various clinically relevant diseases, the book appeals to researchers and clinicians, while also offering a reference guide for scholars who are new to the field.

Materialart: Online-Ressource

Seiten: XII, 348 p. 42 illus., 24 illus. in color. , online resource.

Ausgabe: 1st ed. 2020.

ISBN: 9783030382667

Serie: Advances in Experimental Medicine and Biology, 1233

URL: https://doi.org/10.1007/978-3-030-38266-7

DOI: 10.1007/978-3-030-38266-7

DDC: 571.6

Sprache: Englisch

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Cellular Nanomachines : From Discovery to Structure-Function and Therapeutic Applications (2020)

Jena, Bhanu P.

Cham :Springer International Publishing :

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Schlagwort(e): Cytology. ; Proteins . ; Biophysics. ; Biochemistry. ; Cell Biology. ; Protein Biochemistry. ; Bioanalysis and Bioimaging. ; Chemical Biology. ; Biophysics.

Beschreibung / Inhaltsverzeichnis: Introduction -- Porosome: Cells Secretory Nanomachine -- Ubiquitin-Proteasome Machinery: Cells Garbage Disposal -- Chaperonin: Protein Folding Machinery in Cells -- ATP Synthase: Energy Generator of the Cell -- Ribosome: Cells Protein Synthetic Machinery -- Nuclear Pore: A Bidirectional Transport Machinery -- Myosin: Cellular Molecular Motor -- Assembly of Cellular Nanomachines. Index.

Kurzfassung: In this book, the major paradigm-shifting discoveries made in the past century on key cellular nanomachines are described in great detail: their complex yet precise and elegant design and function, as well as the diseases linked to their dysfunction and the therapeutic approaches to overcome them. The major focus of this book is the “porosome” nanomachine, the universal secretory portal in cells. This is an ideal book for students, researchers, and professionals in the fields of nanoscience and nanotechnology.

Materialart: Online-Ressource

Seiten: XVIII, 109 p. 41 illus., 40 illus. in color. , online resource.

Ausgabe: 1st ed. 2020.

ISBN: 9783030444969

URL: https://doi.org/10.1007/978-3-030-44496-9

DOI: 10.1007/978-3-030-44496-9

DDC: 571.6

Sprache: Englisch

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Regulatory Aspects of Gene Therapy and Cell Therapy Products : A Global Perspective (2023)

Galli, Maria Cristina. [editor.]

Cham :Springer International Publishing :

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Schlagwort(e): Cytology. ; Medical genetics. ; Genetics. ; Cell Biology. ; Medical Genetics. ; Clinical Genetics. ; Genetics.

Beschreibung / Inhaltsverzeichnis: Introduction (MCG and FN) -- Updates on ATMP regulations from EU: experience with PRIME procedure and list of approved ATMP -- EU portal for clinical trials application -- European Pharmacopoeia texts on gene therapy medicinal products -- Updates on ATMP regulations from UK after Brexit and list of approved ATMP -- Updates on ATMP regulations from Switzerland and list of approved ATMP -- Updates on ATMP regulations from US FDA: experience with breakthrough/accelerated procedures and list of approved ATMP -- Updates on ATMP regulations from Canada and list of approved ATMP -- Updates on ATMP regulations from Brasil and list of approved ATMP -- Updates on ATMP regulations from Singapore and list of approved ATMP -- Updates on ATMP regulations from Japan: experience with new law and list of approved ATMP -- Updates on ATMP regulations from South Korea and list of approved ATMP -- Updates on ATMP regulations from Taiwan and list of approved ATMP -- Updates on ATMP regulations from Thailand and list of approved ATMP -- ATMP regulations in China and list of approved ATMP -- ATMP regulations in Australia and list of approved ATMP -- ATMP regulations in India and list of approved ATMP -- International harmonization programs. .

Kurzfassung: This book discusses the different regulatory pathways for Advanced Therapy Medicinal Products implemented by national agencies in North and South America, Europe and Asia and by international bodies in the effort of international harmonization. This book represents an update of the first edition, as it covers regulatory novelties and accumulated experience in the regions already addressed. In addition, this new edition offers a wider international perspective: new chapters are included covering Advanced Therapy Medicinal Products regulations in India, Malaysia, Spain and Thailand, the European Pharmacopoeia texts for gene therapy medicinal products as well as international harmonization programs. Each chapter, authored by experts from various regulatory bodies throughout the international community, walks the reader through the applications of nonclinical research to translational clinical research to licensure and therapeutic use of these innovative products. More specifically, each chapter offers insights into fundamental considerations that are essential for developers of Advanced Therapy Medicinal Products in the areas of product quality, pharmacology and toxicology, clinical trial design and HTA pathways, as well as pertinent ‘must-know’ guidelines and regulations. Regulatory Aspects of Gene Therapy and Cell Therapy Products: a Global Perspective is part of the American Society of Gene & Cell Therapy sub-series of the highly successful Advances in Experimental Medicine and Biology series. It is essential reading for graduate students, clinicians, and researchers interested in gene and cell therapy and the regulation of pharmaceuticals.

Materialart: Online-Ressource

Seiten: IX, 242 p. 37 illus., 36 illus. in color. , online resource.

Ausgabe: 2nd ed. 2023.

ISBN: 9783031345678

Serie: Advances in Experimental Medicine and Biology, 1430

URL: https://doi.org/10.1007/978-3-031-34567-8

DOI: 10.1007/978-3-031-34567-8

DDC: 571.6

Sprache: Englisch

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