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  • Articles  (703)
  • Open Access-Papers  (703)
  • MBL Courses  (698)
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  • 1
    Publication Date: 2021-05-19
    Description: Daily topical application of the aqueous ethanolic extract of the marine sea grass, Thalassia testudinum, on mice skin exposed to UVB radiation resulted in a dose dependent recovery of the skin macroscopic alterations over a 6-day period. Maximal effect (90%) occurred at a dose of 240 μg/cm2, with no additional effects at higher doses. Bioassay-guided fractionation of the plant extract resulted in the isolation of thalassiolin B (1). Topical application of 1 (240 μg/cm2) markedly reduces skin UVB-induced damage. In addition, thalassiolin B scavenged 2,2-diphenyl-2-picrylhydrazyl radical with an EC50=100 μg/ml. These results suggest that thalassiolin B is responsible for the skin regenerating effects of the crude extract of T. testudinum
    Description: Published
    Description: Flavonoids, Thalassiolin B, DPPH scavenged, antioxidant activity, Skin regenerating activity, Thalassia testudinum
    Keywords: Chemistry ; Pharmacology ; Chemistry ; Pharmacology
    Repository Name: AquaDocs
    Type: Journal Contribution
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  • 2
    Publication Date: 2021-05-19
    Description: Bioguided fractionation of Agelas cerebrum crude extract resulted in isolation of four bromopyrrole and four bromopyrrole aminoimidazole alkaloids, identified as 5-bromopyrrole-2-carboxylic acid (1), 4-bromopyrrole-2-carboxylic acid (2), 3,4-bromopyrrole-2-carboxylic acid (3), 4,5-bromopyrrole-2-carboxylic acid (4), oroidin (5), bromoageliferin (6), dibromoageliferin (7) and dibromosceptrin (8) on the basis of spectroscopic data analyses (UV, IR, HRMS, 1D and 2D NMR) and comparison with literature data. This is the first report of compounds 2 and 3 in a marine sponge belonging to the Agelas genus and the first evidence of the presence of 1 from a natural source.
    Description: Published
    Description: Agelas cerebrum, bromopyrrole alkaloids, antitumoral, antiprotozoal activity
    Keywords: Chemistry ; Alkaloids ; Sponges ; Alkaloids ; Sponges ; Chemistry
    Repository Name: AquaDocs
    Type: Journal Contribution
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  • 3
    Publication Date: 2021-05-19
    Description: La velocidad de descomposición de tres fenólicos, el p-hidroxibenzoico, el protocatecúico y el gálico, los cuales se diferencian en el número de grupos OH, fue investigada en el suelo. Con el aumento de grupos OH aumenta también la velocidad de descomposición microbial. El ácido gálico se descompone más rápido que el protocatecúico y este a su vez más rápido que el phidroxibenzoico.
    Description: The rate of decomposition of the three phenolics, p-hydroxybenzoic acid, protocatechuic acid and gallic acid, whose difference is the amount of OH-groups, was investigated in the soil. With the increase in OH-groups increases the rate of microbial decomposition. Gallic acid decomposes faster than protocatecuic acid and this again faster than p-hydroxybenzoic acid.
    Description: Published
    Keywords: Chemical decomposition ; OH Groups ; Microbes ; Phenols ; Chemistry ; Phenols ; Chemistry
    Repository Name: AquaDocs
    Type: Journal Contribution
    Format: pp.141-143
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  • 4
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    Massachusetts Institute of Technology and Woods Hole Oceanographic Institution
    Publication Date: 2022-05-25
    Description: Submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at the Massachusetts Institute of Technology and the Woods Hole Oceanographic Institution May 1998
    Description: Planktonic protozoan grazers have the potential to significantly affect the chemistry of particle-associated trace metals. This is due both to the importance of protists as consumers of bacterial-sized particles, and to the unique low-pH, enzyme-rich microenvironment of the grazer food vacuole. This thesis examines the role of protozoan grazers in the marine geochemistry of strongly hydrolyzed, particle-reactive trace metals, in particular Th and Fe. A series of tracer experiments was carried out in model systems in order to determine the effect of grazer-mediated transformations on the chemical speciation and partitioning of radioisotopes C9Fe, 234Th, 51Cr) associated with prey cells. Results indicate that protozoan grazers are equally able to mobilize intracellular and extracellular trace metals. In some cases, protozoan regeneration of trace metals appears to lead to the formation of metal-organic complexes. Protozoan grazing may generate colloidal material that can scavenge trace metals and, via aggregation, lead to an increase in the metal/organic carbon ratio of aggregated particles. Model system experiments were also conducted in order to determine the effect of grazers on mineral phases, specifically colloidal iron oxide (ferrihydrite). Several independent techniques were employed, including size fractionation ors9Fe-labeled colloids, competitive ligand exchange, and iron-limited diatoms as "probes" for bioavailable Fe. Experimental evidence strongly suggests that protozoan grazing can affect the surface chemistry and increase the dissolution rate of iron oxide phases through phagotrophic ingestion. In further work on protozoan-mediated dissolution of colloidal Fe oxides, a novel tracer technique was developed based on the synthesis of colloidal ferrihydrite impregnated with 133Ba as an inert tracer. This technique was shown to be a sensitive, quantitative indicator for the extent of ferrihydrite dissolution/alteration by a variety of mechanisms, including photochemical reduction and ligand-mediated dissolution. In field experiments using this technique, grazing by naturally occuring protistan assemblages was shown to significantly enhance the dissolution rate of colloidal ferrihydrite over that in non-grazing controls. Laboratory and field results indicate that, when integrated temporally over the entire euphotic zone, protozoan grazing may equal or exceed photoreduction as a pathway for the dissolution of iron oxides.
    Description: This work was financially supported by a Department of Defense ONR-NDSEG Graduate Fellowship, Office ofNaval Research AASERT Award (N00014-94-1-0711), and the National Science Foundation EGB Program (OCE-9523910).
    Keywords: Protozoa ; Water chemistry ; Trace elements in water ; Marine zooplankton ; Chemistry
    Repository Name: Woods Hole Open Access Server
    Type: Thesis
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  • 5
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    Marine Biological Laboratory Archives
    In:  MBL Photographic Collection, Box 2, Folder 3
    Publication Date: 2023-01-11
    Description: Faculty and students in the 1924 Botany course at the Marine Biological Laboratory in Woods Hole, MA
    Description: Photographs
    Keywords: Marine Biological Laboratory (Woods Hole, Mass.) ; MBL Courses
    Repository Name: Woods Hole Open Access Server
    Type: Still Image
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  • 6
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    Marine Biological Laboratory Archives
    In:  MBL Photographic Collection, Box 32
    Publication Date: 2023-01-11
    Description: Faculty and students in the 1992 Microbial Diversity course at the Marine Biological Laboratory in Woods Hole, MA. 2nd view in front of Alvin
    Description: Photographs
    Keywords: Marine Biological Laboratory (Woods Hole, Mass.) ; MBL Courses
    Repository Name: Woods Hole Open Access Server
    Type: Still Image
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  • 7
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    Marine Biological Laboratory Archives
    In:  MBL Photographic Collection, Box 32
    Publication Date: 2023-01-11
    Description: Faculty and students in the 1988 Biology of Parasitism course at the Marine Biological Laboratory in Woods Hole, MA. 2nd view with autoclave bags.
    Description: Photographs
    Keywords: Marine Biological Laboratory (Woods Hole, Mass.) ; MBL Courses
    Repository Name: Woods Hole Open Access Server
    Type: Still Image
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  • 8
    Publication Date: 2023-01-12
    Description: Dedicated to Louis Agassiz
    Description: 1 black and white video; sound (musical accompaniment only); reformatted digital
    Description: By the 1930s, the MBL had become "the" place to go during the summer for biological research and training. Luminaries such as Frank Lillie, Edmund Beecher Wilson, Edwin Grant Conklin, and Thomas Hunt Morgan took their students, packed up their families and research labs, and headed to the MBL. They worked in labs, ate together in the Mess, and they often lived in the limited on-campus housing. Life at the MBL was a life where fun, family, and science intertwined. This film, taken in 1935 by B. R. Coonfield of Brooklyn College, captures snippets of life at the MBL. Though the science and equipment are considerably updated and the faces and families have changed, many features remain the same today.
    Description: Includes (approximate starting time given): Panorama of the Woods Hole area [1:09], view from Cayadetta Wharf [3:12]; Activities in the harbor: passenger plane arrives [4:19], the "Naushon" (a coastal steamer ship operated as a ferry) [4:36], fog [5:05], fishermen [5:33], pleasure boats [7:12]; Oceanographic research vessel "Atlantis" [8:04]; Management: Dr. M. H. Jacobs, Director [9:43], Mr. MacNaught, Business Manager [9:59]; M.B.L. Trustees [10:28]; Unloading supplies [11:10]; Preparing specimens [12:02]; Mending nets [12:43]; Mr. George Gray [13:08]; Instruction: Invertebrate Class collecting expedition [13:55] to North Falmouth [15:15] and Nobska Point [16:54], Embryology Class [17:45], Protozoology Class [18:05], Physiology Class [18:24]; Investigation: Dr. F. R. Lillie [18:51], Dr. E. B. Wilson [19:20], Dr. T. H. Morgan [19:57], Dr. E. G. Conklin [20:22], Dr. C. R. Stockard [20:51], Dr. G. N. Calkins [21:19], Dr. G. H. Parker [21:50], and Dr. R. Chambers [22:13].
    Description: Video
    Keywords: Marine Biological Laboratory (Woods Hole, Mass.) ; Jacobs, M. H. (Merkel Henry) ; MacNaught, Frank M ; Gray, George Milton ; Lillie, Frank Rattray ; Wilson, Edmund B. (Edmund Beecher) ; Morgan, Thomas Hunt ; Conklin, Edwin Grant ; Stockard, Charles R. (Charles Rupert) ; Calkins, Gary N. (Gary Nathan) ; Parker, George Howard ; Chambers, Robert ; People ; Organisms ; Campus ; MBL Courses ; Local Area ; People ; Places ; Organizations
    Repository Name: Woods Hole Open Access Server
    Type: Moving Image
    Format: 23m
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  • 9
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    Marine Biological Laboratory | Arizona Board of Regents
    In:  MBL Archives, Trinkaus Collection, Box 13, Folder 4
    Publication Date: 2023-01-12
    Description: Notes from Oscar Schotte's lecture. Trinkaus continues notes from page 86 on the metamorphosis of echinoderms with five more diagrams (labeled 3-7).
    Description: Lecturer: O. Schotte, Lecture "Metamorphosis of Echinoderms" (Information taken from the 1939 Embryology Course Book)
    Description: Page 88 of 113 from the first notebook of lecture and laboratory notes that John P. Trinkaus took during his time as a student in the Marine Biological Laboratory Embryology Course in 1939 in Woods Hole, MA
    Description: Notes
    Keywords: MBL Courses
    Repository Name: Woods Hole Open Access Server
    Type: Still Image
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  • 10
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    Marine Biological Laboratory | Arizona Board of Regents
    In:  MBL Archives, Trinkaus Collection, Box 13, Folder 4
    Publication Date: 2023-01-12
    Description: Notes from Hubert Goodrich's lecture. Final page of notes from June 20, 1939 lecture, including 'Diff. between two species of Fundulus". Start of notes from Hubert Goodrich's lecture on June 21, 1939, including 'Promorphology of the egg'
    Description: Lecturer: H.B. Goodrich, Lecture "Introductory Announcements. Fish Spawning. Fertilization in Fundulus." (Information taken from the 1939 Embryology Course Book)
    Description: Page 5 of 113 from the first notebook of lecture and laboratory notes that John P. Trinkaus took during his time as a student in the Marine Biological Laboratory Embryology Course in 1939 in Woods Hole, MA
    Description: Notes
    Keywords: MBL Courses
    Repository Name: Woods Hole Open Access Server
    Type: Still Image
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