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  • 1
    Online-Ressource
    Online-Ressource
    Translational Neuroscience of Speech and Language Disorders (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Neurosciences. ; Neuroscience.
    Beschreibung / Inhaltsverzeichnis: 1. Translational Neuroscience of Speech and Language Disorders: State of the Art. -2. Translational Neuroscience of Aphasia and Adult Language Rehabilitation. -3. Treatment and intervention approaches for the improvement of language abilities in neurodegenerative diseases -- 4. Neural and Genetic Mechanisms of Dyslexia -- 5. The role of memory systems in neurodevelopmental disorders of language -- 6. Transcranial direct current stimulation (tDCS) and Language/Speech: Can patients benefit from a combined therapeutic approach? -- 7. Transcranial Magnetic Stimulation in Aphasia Rehabilitation -- 8. The Cerebellum: A Therapeutic Target in Treating Speech and Language Disorders -- 9. Navigated rTMS for Mapping the Language Network in Preoperative Settings: Current Status and Future Prospects -- 10. Presurgical Language fMRI in Epilepsy: An Introduction -- 11. Lesion-symptom mapping in speech and language disorders: a translational perspective.
    Kurzfassung: This edited volume provides the first presentation of the state-of-the-art in the application of modern Neuroscience research in predicting, preventing and alleviating the negative sequelae of neurodevelopmental, acquired, or neurodegenerative conditions on speech and language. It brings together contributions from several leading experts in a markedly broad range of disciplines, including Speech and Language Therapy, Neuropsychology and Neurology, but also Neurosurgery, Neuroimaging and Neurostimulation, as well as Engineering and Genetics.
    Materialart: Online-Ressource
    Seiten: XVII, 290 p. 18 illus., 8 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030356873
    Serie: Contemporary Clinical Neuroscience,
    URL: https://doi.org/10.1007/978-3-030-35687-3
    DOI: 10.1007/978-3-030-35687-3
    DDC: 612.8
    Sprache: Englisch
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  • 2
    Online-Ressource
    Online-Ressource
    Neurosecretion: Secretory Mechanisms (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Neurosciences. ; Anatomy. ; Internal medicine. ; Cytology. ; Biochemistry. ; Neuroscience. ; Anatomy. ; Internal Medicine. ; Cell Biology. ; Biochemistry.
    Beschreibung / Inhaltsverzeichnis: Neurosecretion: A Historical Overview -- Neurosecretion: Hypothalamic Somata versus Neurohypophysial Terminals -- Cyclic ADP-Ribose and Heat Regulate Oxytocin Release via CD38 and TRPM2 in the Hypothalamus -- Somato-Dendritic Secretion of Neuropeptides -- Neurosecretory Vesicles: Structure, Distribution, Release and Breakdown -- Molecular Controls on Regulated Neurotransmitter and Neurohormone Secretion -- Secretory Astrocytes -- Action Potential-Induced Ca2+ Influx for Both Acute and Sustained Insulin Secretion in Pancreatic Beta Cells -- Plasticity in the Morphology of Lactotrophs and Folliculo-Stellate Cells and Prolactin Secretion -- Neuroendocrine and Metabolic Regulation of Plasma Growth Hormone Secretory Profiles -- Role of the TWIK-Related Potassium (TREK)-1 Channels in the Regulation of Adrenocorticotropic Hormone (ACTH) Secretion from Pituitary Corticotropes -- How Do Bacterial Neurotoxins Affect Neurosecretion? -- Secretory Mechanisms in Paramecium.
    Kurzfassung: How do electrical activity and calcium signals in neurons influence the secretion of peptide hormones? This volume presents the current state of knowledge regarding the electrical, calcium signaling and synaptic properties of neuroendocrine systems from both vertebrate and invertebrate systems. The contributions span in vivo and in vitro studies that address: state‐dependent plasticity, relevance of firing patterns, membrane properties, calcium flux (including dynamic imaging and homeostasis), and molecular mechanisms of exocytosis, including from non-neuronal secretory cells. The chapters focus not only on research results but also on how experiments are conducted using state-of-the-art techniques, and how the resulting data are interpreted. While there are many books on the secretory properties of neurons, this is the first to focus on the distinctive secretory properties of neuroendocrine neurons. Accordingly, it offers an important text for undergraduate and graduate neuroscience students, and will also appeal to established scientists and postdoctoral fellows. This is the eighth volume in the Masterclass in Neuroendocrinology series* - now a co-publication between Springer Nature and the INF (International Neuroendocrine Federation). *Volumes 1-7 published by Wiley.
    Materialart: Online-Ressource
    Seiten: XIII, 307 p. 65 illus., 43 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030229894
    Serie: Masterclass in Neuroendocrinology, 8
    URL: https://doi.org/10.1007/978-3-030-22989-4
    DOI: 10.1007/978-3-030-22989-4
    DDC: 612.8
    Sprache: Englisch
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  • 3
    Online-Ressource
    Online-Ressource
    Aging and Hearing : Causes and Consequences (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Neurosciences. ; Otorhinolaryngology. ; Neuroscience. ; Otorhinolaryngology.
    Beschreibung / Inhaltsverzeichnis: Ch 1: Listening to All Voices: Interdisciplinary Approaches to Understanding Hearing in Aging -- Ch 2: Genetic and Molecular Aspects of the Aging Auditory System -- Ch 3: The Aging Cochlea and Auditory Nerve -- Ch 4: Age-Related Changes in the Auditory Brainstem and Inferior Colliculus -- Ch 5: Age related changes in the primate auditory cortex -- Ch 6: The Aging Auditory System: Electrophysiology -- Ch 7: Age-Related Changes in Segregation of Sound Sources -- Ch 8: Causes and Consequences of Age-Related Hearing Loss -- Ch 9: Age-Related Changes in Speech Understanding: Peripheral versus Cognitive Influences -- Ch 10: Aging, Hearing Loss, and Listening Effort: Imaging Studies of the Aging Listener -- Ch 11: Functional Consequences of Impaired Hearing in Older Adults and Implications for Intervention -- Ch 12: Emerging Clinical Translational Treatment Strategies for Age-Related Hearing Loss.
    Kurzfassung: This volume provides contemporary discussions on new developments in aging research. It serves as an important update on the current state of research on the aging auditory system. Listening to All Voices: Interdisciplinary Approaches to Understanding Hearing in Aging Karen S. Helfer and Edward L. Bartlett Genetic and Molecular Aspects of the Aging Auditory System Shinichi Someya and Mi-Jung Kim The Aging Cochlea and Auditory Nerve Kevin K. Ohlemiller and Christopher Spankovich Age-Related Changes in the Auditory Brainstem and Inferior Colliculus Josef Syka Age-Related Changes in the Primate Auditory Cortex Gregg Recanzone The Aging Auditory System: Electrophysiology Kelly C. Harris Age-Related Changes in Segregation of Sound Sources Frederick J. Gallun and Virginia Best Causes and Consequences of Age-Related Hearing Loss Jennifer A. Deal, Nicholas S. Reed, Emily C. Pedersen, and Frank R. Lin Age-Related Changes in Speech Understanding: Peripheral versus Cognitive Influences Sandra Gordon-Salant, Maureen J. Shader, and Arthur Wingfield Aging, Hearing Loss, and Listening Effort: Imaging Studies of the Aging Listener Stefanie E. Kuchinsky and Kenneth I. Vaden, Jr. Functional Consequences of Impaired Hearing in Older Adults and Implications for Intervention Larry E. Humes, M. Kathleen Pichora-Fuller, and Louise Hickson Emerging Clinical Translational Treatment Strategies for Age-Related Hearing Loss Robert D. Frisina, Carlos J. Cruz, Tanika T. Williamson, Xiaoxia Zhu, and Bo Ding .
    Materialart: Online-Ressource
    Seiten: XVII, 323 p. 62 illus. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030493677
    Serie: Springer Handbook of Auditory Research, 72
    URL: https://doi.org/10.1007/978-3-030-49367-7
    DOI: 10.1007/978-3-030-49367-7
    DDC: 612.8
    Sprache: Englisch
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  • 4
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    Prions and Diseases (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Human physiology. ; Neurology . ; Life sciences. ; Physiology. ; Neuroscience. ; Human Physiology. ; Neurology. ; Life Sciences. ; Animal Physiology. ; Life Sciences.
    Beschreibung / Inhaltsverzeichnis: Part I: HISTORY -- Chapter 1: Transmissible Spongiform Encephalopathy: from its beginnings to Daniel Carleton Gajdusek -- Part II: GENERAL ASPECTS OF PRIONS -- Chapter 2: The Rich Chemistry of the Copper and Zinc Sites in Cellular Prion Protein -- Chapter 3: Mammalian Prion Structures -- Chapter 4: Insoluble Cellular Prion Protein and Other Neurodegeneration-related Misfolded Protein Aggregates in the Brain of Asymptomatic Individuals -- Part III: CONVERSION AND STRAIN OF PRIONS -- Chapter 5: Prion Conversion and Deformed Templating -- Chapter 6: Prion Strain Interference -- Chapter 7: Molecular Mechanisms Encoding Strains of Prions and Prion-Like Misfolded Proteins -- Chapter 8: Cofactor Involvement in Prion Propagation -- Chapter 9: Prion Protein Conversion and Lipids -- Part IV: ENVIRONMENT AND TRANSMISSION OF PRIONS -- Chapter 10: Prions in the Environment -- Chapter 11: Environmentally Acquired Transmissible Spongiform Encephalopathy -- Chapter 12: Risk of Transmission of Creutzfeldt-Jakob Disease by Blood Transfusion -- Chapter 13: Species Barriers in Prion Disease -- Part V: MODELLING OF PRIONS -- Chapter 14: Modeling the Cell Biology of Prions -- Chapter 15: Transgenic Mice Modelling in Prion Diseases -- Chapter 16: Stem Cell Models in Prion Research -- Chapter 17: Drosophila Models of Prion Diseases -- Part VI: HUMAN PRION DISEASES AND OTHER PATHOLOGIES -- Chapter 18: Human Sporadic Prion Diseases -- Chapter 19 Genetic Creutzfeldt-Jakob and Gerstmann-Sträussler-Scheinker Diseases -- Chapter 20: Glycoform-selective Prions in Sporadic and Inherited Variably Protease-sensitive Prionopathies -- Chapter 21: The Spectrum of Tau Pathology in Human Prion Disease -- Chapter 22: Prion Protein Complex with mGluR5 Mediates Amyloid-ß Synaptic Loss in Alzheimer’s Disease -- Chapter 23: Prion and Cancers -- Chapter 24: Protective Role of Cellular Prion Protein in Tissue Ischemic/Reperfusion Injury -- Part VII: ANIMAL PRION DISEASES -- Chapter 25: Bovine Spongiform Encephalopathy -- Chapter 26: Classical and Atypical Scrapie in Sheep and Goats -- Chapter 27: Research models for studying chronic wasting disease -- Part VIII: YEAST PRIONS -- Chapter 28: Introduction to Yeast and Fungal Prions -- Chapter 29: Yeast Prions Are Folded, In-Register Parallel Amyloids Subject to Multiple Anti-prion Systems -- Part IX: DIAGNOSIS AND HUMAN PRION SURVEILLANCE -- Chapter 30: Real-time quaking-induced conversion (QuIC) assays for the detection and diagnosis of human prion diseases -- Chapter 31: Protein Misfolding Cyclic Amplification -- Chapter 32: Skin Misfolded Proteins as Biomarkers for Diagnosis of Prion and Prion-like Diseases -- Chapter 33: Diagnosis of Prion Disease: Conventional Approaches -- Chapter 34: Human Prion Disease Surveillance -- Part X: TREATMENT -- Chapter 35: Overview on Treatment of Prion Diseases and Decontamination of Prions -- Chapter 36: Gene Therapy Strategies for Prophylactic and Therapeutic Treatments of Human Prion Diseases -- Chapter 37: Immunomodulation.
    Kurzfassung: Transmissible spongiform encephalopathies (TSE), now known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. Modern studies, including protein-misfolding cyclic amplification (PMCA), have greatly advanced our understanding of the pathogenesis of prion diseases and facilitated the identification of new prion diseases in animals and humans. In the second edition of Prions and Diseases, more than 60 leading researchers and clinicians worldwide provide an up-to-date discussion of these unique infectious pathogens and their associated diseases. The book provides up-to-date knowledge about the etiology, pathogenesis, classification, histopathological, and clinical aspects of the full range of animal and human prion diseases. As a result, the book contains the most authoritative views about the past, present, and future of prions and prion diseases covering fresh perspectives on important emerging topics such as inherited human prion disease, stem-cell models in prion research, human prion disease surveillance, and gene therapy strategies.
    Materialart: Online-Ressource
    Seiten: XII, 793 p. 81 illus., 62 illus. in color. , online resource.
    Ausgabe: 2nd ed. 2023.
    ISBN: 9783031205651
    URL: https://doi.org/10.1007/978-3-031-20565-1
    DOI: 10.1007/978-3-031-20565-1
    DDC: 612.8
    Sprache: Englisch
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  • 5
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    Online-Ressource
    Flexible High Performance Magnetic Field Sensors : On-Scalp Magnetoencephalography and Other Applications (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Neurosciences. ; Biomedical engineering. ; Nanotechnology. ; Biophysics. ; Imaging systems in biology. ; Neuroscience. ; Biomedical Engineering and Bioengineering. ; Nanoengineering. ; Bioanalysis and Bioimaging. ; Biological Imaging.
    Beschreibung / Inhaltsverzeichnis: Part 1 -- Optically-Pumped Magnetometers Compatible with Large Transient Magnetic Fields -- Small animal biomagnetism applications -- Supine OPM-MEG in Multi-layer Cylindrical Shield -- Ambulatory MEG Arrays -- Part 2 -- "Tri-axial helium-4 optically-pumped -- magnetometers for MEG" -- Person-Sized Magnetoencephalography Systems with Optically Pumped Magnetometers -- On-scalp MEG with High-Tc SQUIDs -- "Fiber Coupled OPM in Purely Coil -- Shielded Environment" -- SERF-OPM usability for MEG in two-layer shielded rooms -- Turning OPM-MEG into a Wearable Technology -- Part 3 -- OPM Gradiometer for Magnetorelaxometry -- Unshielded High Bandwidth Magnetorelaxometry of Magnetic Nanoparticles with Optically Pumped Magnetometers -- Adult Magnetocardiography: Principles and Clinical Practice -- Fetal Magnetocardiography with OPMs -- Emerging MR sensors for biomagnetic measurements -- Index.
    Kurzfassung: This contributed volume reviews the latest advances in all the new technologies currently developed for MagnetoEncephaloGraphy (MEG) recordings, as well as sensor technologies and integrated sensor arrays for on-scalp MEG. The book gives an account of the first MEG imaging studies and explores the new field of feasible, experimental paradigms of on-scalp MEG. This is an ideal book for engineers, researchers, and students in the neurosciences interested in MEG imaging. .
    Materialart: Online-Ressource
    Seiten: IX, 315 p. 104 illus., 88 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031053634
    URL: https://doi.org/10.1007/978-3-031-05363-4
    DOI: 10.1007/978-3-031-05363-4
    DDC: 612.8
    Sprache: Englisch
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  • 6
    Online-Ressource
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    Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Neurosciences. ; Neuroscience.
    Beschreibung / Inhaltsverzeichnis: 1. Introduction Food and Brain -- 2. Food and Behavior -- 3. Food and Psychological Wellbeing -- 4. Food and Cognition -- 5. Autism and Food -- 6. Healthy Brains: Types of Food and their Active Pharmacological Ingredients -- 5. Dieting: Importance of Diet and Diet Types -- 6. Nutrigenomics -- 7. Epigenetics -- 8. Gut Microbiota (microbiome) -- 9. Personalized Nutrition -- 10. Vegetables -- 11. Fruits -- 12. Nuts, Seeds and Spices -- 13. Grains [Oats, Barley & Quinoa] -- 14. Seafood [fish like Salmon, Oyster, Sea vegetables (algae)] -- 15. Other -- 16. Autism Management through Food and Diet -- 17. Personalized Nutrition Therapy.
    Kurzfassung: The book focuses on implications of traditional and processed foods for autism spectrum disorder (ASD) intervention and management. Numerous phytonutrients and pharmacologically active compounds in edible natural products and diet could influence and offer protection to neuronal dysfunction that occurs due to ASD. The neuroprotective effects of various fruits, vegetables, nuts and seeds phytochemicals, and other natural bioactive ingredients against ASD and related conditions are discussed. Topics such as the possible neuroprotective mechanism of action of these foods and the therapeutic role of antioxidants in relation to ASD are addressed. This book also highlights the scope of using anti-inflammatory agents and antioxidants to promote neurogenesis and improve other symptoms in ASD. It emphasizes personalized nutritional approaches with dietary management of neurodevelopmental disorders/ASD cases. Information in this book is relevant to researchers in the field of complementary and alternative medicine, nutraceuticals, neuroscience, agriculture, nutrition, and food science. This volume is beneficial to students of varying levels, and across multiple disciplines.
    Materialart: Online-Ressource
    Seiten: XX, 693 p. 111 illus., 68 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030304027
    Serie: Advances in Neurobiology, 24
    URL: https://doi.org/10.1007/978-3-030-30402-7
    DOI: 10.1007/978-3-030-30402-7
    DDC: 612.8
    Sprache: Englisch
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  • 7
    Online-Ressource
    Online-Ressource
    Pharmacology in Clinical Neurosciences : A Quick Guide (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Neurosciences. ; Pharmacology. ; Anesthesiology. ; Neuroscience. ; Pharmacology. ; Anesthesiology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Analgosedation -- Chapter 2. Inhalational Anesthetics -- Chapter 3. Intravenous Anesthetic Agents -- Chapter 4. Local Anesthetics -- Chapter 5. Neuromuscular Blocking Drugs (nmbds) -- Chapter 6. Reversal Agents and Antagonists -- Chapter 7. Anticholinergics -- Chapter 8. Anti-epileptic Drugs (aeds) -- Chapter 9. Osmotherapy -- Chapter 10. Antibiotics -- Chapter 11. Anti-viral -- Chapter 12. Antifungal -- Chapter 13. Anticoagulants and Antiplatelets -- Chapter 14. Glucocorticoids -- Chapter 15. Antihypertensives -- Chapter 16. Vasopressors -- Chapter17. Antipsychotics -- Chapter 18. Miscellaneous drugs. .
    Kurzfassung: The pharmacodynamics and pharmacokinetics of several drugs is expected to be known to clinicians and researchers at all times. With advances in sciences and development of newer drugs very frequently, it is very important to keep your knowledge updated at all times. This title is a quick guide to researchers and clinicians for a quick reference. The title is also a vital resource for all streams of neurosciences (neuroanesthesia and neurointensive care) and is much different from a conventional pharmacology titles, being more reader friendly and to the point facilitated with numerous flowcharts and algorithms with each chapter being prepared in a standard structured manner.
    Materialart: Online-Ressource
    Seiten: VII, 1074 p. 331 illus., 108 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811535918
    URL: https://doi.org/10.1007/978-981-15-3591-8
    DOI: 10.1007/978-981-15-3591-8
    DDC: 612.8
    Sprache: Englisch
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  • 8
    Online-Ressource
    Online-Ressource
    Patterns of Parental Behavior : From Animal Science to Comparative Ethology and Neuroscience (2022)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Animal culture. ; Veterinary medicine. ; Neuroscience. ; Animal Science. ; Veterinary Science.
    Beschreibung / Inhaltsverzeichnis: Rodents -- Carnivores -- Sheep and goats -- Swine -- Rabbits -- Bovines -- Non-human primates -- Humans -- Squirrels.
    Kurzfassung: Modern neuroscience has presented new opportunities for exploring the molecular and neural mechanisms controlling specific social responses. This book reviews insights into the neural circuits underlying a particularly fascinating form of social interaction, parental behavior. This book presents a detailed review of maternal and paternal behavior of particular mammalian species. It offer neuroscientists a spectrum of specific mammals that can be used as experimental models to explore particular topics on the functions of the nervous system. It shows that results coming from the laboratory can be translated into useful information for raising mammals on the farm, and it stimulates biologists to gain insights into the underpinnings of the complex mechanisms governing mammalian behavior in the wild. It also discusses the implications of this research for human parental behavior. .
    Materialart: Online-Ressource
    Seiten: V, 309 p. 45 illus., 39 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030977627
    Serie: Advances in Neurobiology, 27
    URL: https://doi.org/10.1007/978-3-030-97762-7
    DOI: 10.1007/978-3-030-97762-7
    DDC: 612.8
    Sprache: Englisch
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  • 9
    Online-Ressource
    Online-Ressource
    Brain Development of Medaka Fish : A New Concept of Brain Morphogenesis in Vertebrates (2022)
    Singapore :Springer Nature Singapore :
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    Schlagwort(e): Neurosciences. ; Life sciences. ; Biology Technique. ; Evolution (Biology). ; Neuroscience. ; Life Sciences. ; Experimental Organisms. ; Evolutionary Biology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction -- Chapter 2.General Rules of Brain Morphogenesis in Vertebrates: An Hourglass Model -- Chapter 3.Neural Tube Formation -- Chapter 4.Subdivisions of Neural tube along the Dorsoventral Axis -- Chapter 5. Subdivisions of Neural Tube along the Rostrocaudal Axis: Neuromeric Models -- Chapter 6.Left-right Patterning of Neural Tube -- Chapter 7. Ventriculo-pial Patterning of Neural Tube -- Chapter 8.Development of Neural Circuits in Neural Tube -- Chapter 9.From Neural Tube to Larval Brain: Blood Vessels and Proliferative Zones -- Chapter 10. Development of Telencephalon -- Chapter 11. Development of Diencephalon, Optic Tectum, and Cerebellum -- Chapter 12. Nervous System in Medaka Larvae -- Chapter 13.From Larval Brain to Adult Brain and Summary of Telencephalic Ontogenesis -- Chapter 14. Adult Brain and General Brain Functions -- Chapter 15. Functional Neuroanatomy of Teleost Brains.
    Kurzfassung: This book describes the developmental process of the brain of the medaka fish. It aims to understand the brain structure of vertebrates, including humans, by taking the brain of the medaka fish as an example and showing its actual developmental process. From developmental and evolutionary viewpoints, the understanding of the brain proceeds from simple to complex structures. Fish retain the basic form of vertebrates, and their brain morphology is relatively simple. Therefore, the fish brain is useful in understanding the brain structure. This book is unique for describing the entire process of the brain development in a specific fish. In addition, the book introduces the readers to a new concept of “Hourglass of Brain Morphogenesis”, concerning the general rule of brain morphogenesis in vertebrates. The authors propose that the brain morphology is highly conserved at the middle developmental stage but diverges more extensively at earlier and later stages. The new concept challenges the accepted theory that has been widely shared for about 200 years since K. von Baer (1828, 1837) and K. von Kupffer (1906) who proposed that three primary brain vesicles at earlier developmental stages develop into five secondary brain vesicles at later developmental stages in all vertebrates. The book provides a basic understanding of the vertebrate brain and is useful for all readers who wish to understand the complex structure of the brain. .
    Materialart: Online-Ressource
    Seiten: XIV, 256 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811943249
    URL: https://doi.org/10.1007/978-981-19-4324-9
    DOI: 10.1007/978-981-19-4324-9
    DDC: 612.8
    Sprache: Englisch
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  • 10
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    Neuroimmune Interactions in Pain : Mechanisms and Therapeutics (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Pain medicine. ; Neurology . ; Anesthesiology. ; Neuroscience. ; Pain Medicine. ; Neurology. ; Anesthesiology.
    Beschreibung / Inhaltsverzeichnis: Introduction to Acute, Chronic, and Episodic Pain -- Inflammation and Pain -- Animal Models of Pain and Anti-inflammatory Treatments -- Inflammatory Mediators, Nociceptors, and Their Interactions in Pain -- Immune and Glial Cells in Pain and Their Interactions with Nociceptive Neurons -- Sex Differences in Neuroimmune Interactions and Pain -- Neuroimmune Interactions in Itch -- Toll-like Receptors in Pain and Itch -- Immunotherapy and Pain -- Cell Therapy and Regenerative Pain Medicine - Preclinical Studies -- Cell-based Therapies in Pain Management -- Platelet-Rich Plasma and Autologous Conditioned Serum: Non-Cellular Biologic Therapies for Neuroimmune Modulation and the Treatment of Arthritis Pain -- Exercise and Diet in the Control of Inflammation and Pain -- Mechanism-Based Pain Therapies -- Neuromodulation in Pain Management -- What Patients Need to Know about Pain Therapy?.
    Kurzfassung: As lifespans increase, more people around the world find themselves victims of chronic pain. In spite of this, treatment options continue to be severely limited. Anti-inflammatory drugs can only do so much, while painkillers like opioids have led to crippling addictions and fatal overdoses. The subject of the book is the role of immune cells, including glial cells, and neuroimmune interactions in chronic pain. The book begins by examining the preclinical and clinical evidence supporting the involvement of non-neuronal cells in chronic pain. It discusses the interactions between non-neuronal cells and neurons in the regulation of chronic pain. It then presents the implications of these findings, including promising and emerging treatments such as specialized pro-resolving mediators (SPMs, such as resolvins and protectins), immune cell therapy, and complementary and alternative medicine, as well as neuromodulation and regenerative medicine, which may prove to be the turning point for hundreds of millions of patients world-wide who struggle to escape from the shadow of chronic pain. The book presents ground-breaking research that will alter current perspectives on chronic pain.
    Materialart: Online-Ressource
    Seiten: X, 364 p. 45 illus., 41 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031292316
    URL: https://doi.org/10.1007/978-3-031-29231-6
    DOI: 10.1007/978-3-031-29231-6
    DDC: 612.8
    Sprache: Englisch
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  • 11
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    Sleep: Evolution and Functions (2020)
    Singapore :Springer Nature Singapore :
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    Schlagwort(e): Neurosciences. ; Neurology . ; Evolution (Biology). ; Psychobiology. ; Human behavior. ; Neuroscience. ; Neurology. ; Evolutionary Biology. ; Behavioral Neuroscience.
    Beschreibung / Inhaltsverzeichnis: Sleep: Basic and Historical Aspects -- Sleep: Findings in Invertebrates and Lower Vertebrates -- Sleep: Evolutionary and Adaptive Changes in Birds and Mammals -- Sleep Loss: What Does it do to our Brain and Body -- Sleep: Neural Optimization as An Ultimate Function for Memory Consolidation -- Sleep: Disorders and Clinical Implications.
    Kurzfassung: This book discusses the evolution of sleep and its possible function in the higher invertebrates and vertebrates, including humans. It describes the current concept of sleep and its functions, based on research on the mammalian system. To date, electrophysiological recordings of the brain waves, muscle activity, and eye movements are the only tools available for characterizing the sleep architecture in the majority of animals. In mammals and birds, only two distinct types of sleep are found – non-rapid eye movement (NREM) and rapid eye movement (REM) sleep. Since the discovery of REM sleep, studies have been performed to understand the purpose of the two distinct sleep states in higher vertebrates (birds and mammals), and how REM sleep was evolved. The book summarizes the role of both REM and NREM sleep in the proper functioning of the brain and body. It covers various aspects of the role of sleep in important physiological processes, including memory consolidation, induction of synaptic plasticity, energy restoration, enhancing immune response, and maturation of neuronal circuitries during early life. Lastly, the book reviews the effects of chronic/acute sleep deprivation on memory consolidation, obesity, and the immune system in animal models and humans.
    Materialart: Online-Ressource
    Seiten: XIV, 118 p. 30 illus., 26 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811571756
    URL: https://doi.org/10.1007/978-981-15-7175-6
    DOI: 10.1007/978-981-15-7175-6
    DDC: 612.8
    Sprache: Englisch
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  • 12
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    Modern Approaches to Augmentation of Brain Function (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Neurosciences. ; Neuroscience.
    Beschreibung / Inhaltsverzeichnis: 1. Using electrical stimulation to explore and augment the functions of parietal-frontal cortical networks in primates -- 2. Multi-system benefits of epidural stimulation following spinal cord injury. 3. Neurostimulator for hippocampal memory prosthesis -- 4. Modern approaches to augmenting the brain functions -- 5. Brain machine interfaces within a critical perspective -- 6. An implantable wireless device for ECoG and cortical stimulation -- 7. BCI Performance improvement by special low jitter quasi-steady State VEP paradigm -- 8. Communication with Brain-Computer Interfaces in Medical Decision-Making -- 9. Neuroprotection and neurocognitive augmentation by photobiomodulation -- 10. Avoiding partial sleep - the way for augmentation of brain function -- 11. Augmentation of brain functions by nanotechnology -- 12. The impact of ageing and age-related comorbidities on stroke outcome in animal models and humans -- 13. Diagnostic markers of sub-clinical depression based on functional connectivity -- 14. Transcranial magnetic stimulation in autism spectrum disorders: modulating brainwave abnormalities and behaviors -- 15. Neurofeedback training with concurrent psychophysiological monitoring in children with autism spectrum disorder with comorbid attention deficit/hyperactivity disorder -- 16. Augmentation through interconnection: brain-nets and telemedicine -- 17. Cognitive augmentation via a brain/cloud interface -- 18. Augmentation of neuro-marketing by neural technology -- 19. Augmentation of nutrition by nanotechnology -- 20. Neural spintronics: noninvasive augmentation of brain functions -- 21. Does the power to suppress an action make us free? -- 22. Deep brain stimulation for Parkinson’s disease-future directions for enhancing motor function -- 23. Neuromodulation for gait -- 24. Augmentation and rehabilitation with active orthotic devices -- 25. Effects of rTMS on behavioral and electrocortical measures of error monitoring and correction function in children with autism spectrum disorder -- 26. Affective Virtual Reality Gaming for Autism -- 27. A machine learning approach to automatic phobia therapy with virtual reality -- 28. Vision augmentation by pharmacological enhancement of the visual experience -- 29. Cognitive enhancing substances and the developing brain: risks and benefits -- 30. Pharmacological approaches in the augmentation and recovery of brain function.
    Kurzfassung: This book covers recent advances in the neural technology that produces enhancements for brain function. It addresses a broad range of neural phenomena occurring in the brain circuits for perception, cognition, emotion and action, representing the building blocks of the behavior and mind. Augmentation of brain function is achieved using brain implants for recordings, stimulation and drug delivery. Alternative methods include employing brain-machine interfaces, as well as noninvasive activation of certain brain areas. Existing methods of brain augmentation are evaluated, and new approaches are introduced. Brain circuitry and neuronal mechanisms that are candidates for augmentation are discussed. This volume provides novel insights into brain disorders, and new devices for brain repair. Information in this book is relevant to researchers in the field of neuroscience, engineering, and clinical practice. Philosophical and ethical implications of brain augmentation are also addressed. “This impressive book by leading experts in neuroscience and neuroengineering lays out the future of brain augmentation, in which the human mind and machine merge, leading to a rapid exponential growth of the power of humanity.” – Ray Kurzweil "This book employs a holistic approach in covering the recent advances in the fields of neuroscience, neuroinformatics, neurotechnology and neuro-psycho-pharmacology. Each chapter of the book covers major aspects of modern brain research in connection with the human mind and behavior, and is authored by researchers with unique expertise in their field. " – Ioan Dumitrache “This book presents compelling perspectives on what interactive neuroscience will look like in the future, delving into the innovatory ideas of a diverse set of neuroscientists, and speculating on the different ways computer chips implanted in the brains of humans can effect intelligence and communication.” – György Buzsáki.
    Materialart: Online-Ressource
    Seiten: XXII, 747 p. 189 illus., 153 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030545642
    Serie: Contemporary Clinical Neuroscience,
    URL: https://doi.org/10.1007/978-3-030-54564-2
    DOI: 10.1007/978-3-030-54564-2
    DDC: 612.8
    Sprache: Englisch
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  • 13
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    Neural Circuits of Innate Behaviors (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Neurosciences. ; Medicine Research. ; Biology Research. ; Psychology. ; Neuroscience. ; Biomedical Research. ; Behavioral Sciences and Psychology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Neural Circuits Underlying Innate Fear -- Chapter 2: Neurobiology and Neural Circuits of Aggression -- Chapter 3: Neural Regulation of Feeding Behavior -- Chapter 4: Neural Circuits for Reward -- Chapter 5: Neuronal response and behavioral modulation in social interaction -- Chapter 6: Neural circuit mechanisms that underlie parental care -- Chapter 7: Spatial navigation -- Chapter 8: Neural circuits for sleep-wake regulation.
    Kurzfassung: This book summarizes the latest research findings in the neurocircuitry of innate behaviors, covering major topics such as innate fear, aggression, feeding, reward, social interaction, parental care, spatial navigation, and sleep-wake regulation. For decades, humans have been fascinated by wild animals’ instincts, like the annual two-thousand-mile migration of the monarch butterfly in North American, and the “imprint” behavior of newborn birds. Since these instincts are always displayed in stereotypical patterns in most individuals of a given species, the neural circuits processing such behaviors must be genetically hard-wired in the brain. Recently, with the development of modern techniques, including optogenetics, retrograde and anterograde virus tracing, and in vivo calcium imaging, researchers have been able to determine and dissect the specific neural circuits for many innate behaviors by selectively manipulating well-defined cell types in the brain. This book discusses recent advances in the investigation of the neural-circuit mechanisms underlying innate behaviors.
    Materialart: Online-Ressource
    Seiten: IX, 112 p. 13 illus., 10 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811570865
    Serie: Advances in Experimental Medicine and Biology, 1284
    URL: https://doi.org/10.1007/978-981-15-7086-5
    DOI: 10.1007/978-981-15-7086-5
    DDC: 612.8
    Sprache: Englisch
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  • 14
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    Online-Ressource
    Social and Affective Neuroscience of Everyday Human Interaction : From Theory to Methodology (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Cognitive neuroscience. ; Psychobiology. ; Human behavior. ; Sociology. ; Neuroscience. ; Cognitive Neuroscience. ; Behavioral Neuroscience. ; Sociology.
    Beschreibung / Inhaltsverzeichnis: Molecular imaging of the human emotion circuit -- The neurocognitive mechanisms of unconscious emotional responses -- Social and Affective Neuroscience of Embodiment -- The neuroscience of beauty -- Mirror Neurons … in action: ERPs and neuroimaging evidence -- Sex differences in social cognition -- Development of morality and emotional processing -- Trust in Social Interaction: From Dyads to Civilizations -- The time has come to be mindwanderful: Mind wandering and the intuitive psychology mode -- Social Cognition development and socio affective dysfunction in childhood and adolescence -- Clinical neuroscience meets second-person neuropsychiatry -- EEG and ERPs in the study of Language and Social Knowledge -- fMRI and fNIRS methods for social brain studies: hyperscanning possibilities -- Modulating the Social and Affective Brain with transcranial stimulation techniques -- What our eyes can tell us about our social and affective brain? -- Facial EMG – Investigating the interplay of facial muscles and emotions.
    Kurzfassung: This Open Access book presents the current state of the art knowledge on social and affective neuroscience based on empirical findings. This volume is divided into several sections first guiding the reader through important theoretical topics within affective neuroscience, social neuroscience and moral emotions, and clinical neuroscience. Each chapter addresses everyday social interactions and various aspects of social interactions from a different angle taking the reader on a diverse journey. The last section of the book is of methodological nature. Basic information is presented for the reader to learn about common methodologies used in neuroscience alongside advanced input to deepen the understanding and usability of these methods in social and affective neuroscience for more experienced readers.
    Materialart: Online-Ressource
    Seiten: XXXIII, 302 p. 55 illus., 48 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031086519
    URL: https://doi.org/10.1007/978-3-031-08651-9
    DOI: 10.1007/978-3-031-08651-9
    DDC: 612.8
    Sprache: Englisch
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  • 15
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    Online-Ressource
    Pharmacoresistance in Epilepsy : From Genes and Molecules to Promising Therapies (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Neurology . ; Pharmacology. ; Neuroscience. ; Neurology. ; Pharmacology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Why study Drug Resistant Epilepsy? -- Chapter 2: Pharmacoresistance in Epilepsy -- Chapter 3: Experimental models for the study of drug-resistant epilepsy -- Chapter 4: On Complexity and Emergence: Linking the Hypotheses of Pharmacoresistance in Epilepsy -- Chapter 5: Role of High-Frequency Oscillation Networks in Managing Pharmacoresistant Epilepsy -- Chapter 6: Transporter hypothesis in pharmacoresistant epilepsies. Is it at the central or peripheral level? -- Chapter 7: Changes in Targets as an Explanation for Drug Resistance in Epilepsy -- Chapter 8: Cellular and molecular mechanisms of neuroinflammation in drug-resistant epilepsy -- Chapter 9: Contribution of the antiepileptic drug administration regime to avoid the development and/or establishment of pharmacoresistant epilepsy -- Chapter 10: Pharmacogenetics in Epilepsy and Refractory Epilepsy -- Chapter 11: Seizures Induce Hypoxia or Hypoxia Induces Seizures. A Perverse Relationship that Increases the Risk of SUDEP -- Chapter 12: Neonatal excitotoxicity triggers degenerative processes related to seizure susceptibility and pharmacoresistance -- Chapter 13: Cerebrovascular remodeling and the role of vascular endothelial growth factor in the epileptic brain and pharmacoresistance -- Chapter 14: The Role of JNK3 in Epilepsy and Neurodegeneration -- Chapter 15: Application of proteomics in the study of molecular markers in epilepsy -- Chapter 16: GABAergic neurotransmission abnormalities in pharmacoresistant epilepsy: experimental and human studies -- Chapter 17: Genes involved in pharmacoresistant epilepsy -- Chapter 18: Drug-resistant Epilepsy and the Influence of Age, Gender and Comorbid Disorders -- Chapter 19: Indications for Intracerebral Recording in Candidates for Epilepsy Surgery -- Chapter 20: On the Development of New Drugs for the Treatment of Drug Resistant Epilepsy: An Update on Different Approaches to Different Hypotheses -- Chapter 21: Physical exercise as a strategy to reduce seizure susceptibility -- Chapter 22: Ketogenic Diet and Drug-resistant Epilepsy -- Chapter 23: Modulating P-glycoprotein Regulation as a Therapeutic Strategy for Pharmacoresistant Epilepsy -- Chapter 24: Vagus Nerve Stimulation for Intractable Seizures -- Chapter 25: Non Invasive Brain Stimulation as a potential Therapeutic Procedure in drug-resistant epilepsy -- Chapter 26: Effects of transcranial focal electrical stimulation via concentric ring electrodes on seizure activity.
    Kurzfassung: This new edition of Pharmacoresistance in Epilepsy addresses all issues relating to drug-resistance in epilepsy, including studies in patients as well in experimental models and presents the basis for an understanding of recent developments in the pathogenesis and treatment of this condition. Important issues associated with drug-resistant epilepsy are reviewed and updated, such as abnormalities in inhibitory mechanisms, neurotoxicity and changes the immune system associated with this disorder, and the development of drug-resistance as consequence of chronic exposure to antiseizure-medications. Considering that a major obstacle is that epilepsy associated with drug-resistance cannot be controlled with the traditional antiseizure medications, specific chapters describe therapeutic strategies to prevent or reduce the progression of the disease with complementary medical therapies, such as transcranial focal stimulation to promote neuroprotection. Pharmacoresistance in Epilepsy is a valuable resource for anyone working in the field, whether studying epilepsy in the lab or treating it in an office.
    Materialart: Online-Ressource
    Seiten: XV, 596 p. 84 illus., 79 illus. in color. , online resource.
    Ausgabe: 2nd ed. 2023.
    ISBN: 9783031365263
    URL: https://doi.org/10.1007/978-3-031-36526-3
    DOI: 10.1007/978-3-031-36526-3
    DDC: 612.8
    Sprache: Englisch
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  • 16
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    Development of the Cerebellum from Molecular Aspects to Diseases (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Neurosciences. ; Neurology . ; Developmental neurobiology. ; Neuroscience. ; Neurology. ; Development of the Nervous System.
    Beschreibung / Inhaltsverzeichnis: The development of the cerebellum: from the beginnings -- Part I: Responsibilities and liabilities -- Chapter2. The embryology and anatomy of the cerebellum -- Chapter 3. Cellular and genetic programs underlying cerebellum development -- Chapter 4. Early Purkinje Cell Development and the Origins of Cerebellar Patterning. - Chapter 5. Development of the Fish Cerebellum. -Chapter 6. Cerebellar developmental disorders and cerebellar nuclei -- Chapter 7. Motor circuit abnormalities during cerebellar development -- Chapter8. Developmental disorders of the cerebellum and neurotrophic factors -- Chapter9. Apoptosis, Autophagy, and Unfolded Protein Response and Cerebellar Development -- Chapter10. The ubiquitin proteasome system and cerebellar developmental disease -- Chapter11. Epigenetics and Cerebellar Neurodevelopmental Disorders -- Chapter12.. Hormonal regulation of cerebellar development and its disorders -- Chapter13. Infections of the Cerebellum -- Chapter14. Neuroimmune mechanisms of cerebellar development and its developmental disorders -- Chapter15. Teratogenic influences on cerebellar development -- Chapter16. Primary pediatric brain tumors of the posterior fossa -- Chapter17. Primary pediatric brain tumors of the posterior fossa -- Chapter18. Can cerebellar neurodevelopmental disorders affect behavioral disorders or vice versa -- Chapter19. Neurodevelopmental disorders of the cerebellum: autism spectrum disorder -- Chapter20. Congenital cerebellar disease -- Chapter21. Clinical features, assessment, and management of patients with developmental and other cerebellar disorders -- Chapter22. Epidemiology of cerebellar disorders -- Chapter23. Cerebellar transplantation: a potential model to study repair and development of neurons and circuits in the cerebellum. - Chapter 24. Non-coding RNAs and cerebellar development. - Chapter 25. Defining the Cerebellar Cytoarchitecture Using MRI. .
    Kurzfassung: This updated reference covers diverse aspects of cerebellar development from a full range of viewpoints, including the epidemiology of cerebellar genetic disorders, developmental anatomy, cell biology, genetics, epigenetics, infectious diseases, and mechanisms involved in the regulation of cell fate, while also focusing on information that is relevant to clinicians caring for patients with cerebellar disorders. The chapters are written by experts in the field of cerebellar development, and the chapters cover diseases related to the cerebellum, along with their epidemiology, clinical features, assessment, and management. In addition to updating the content to cover the significant developments in the field since the first edition, the second edition will include new chapters on Non-Coding RNAs and Cerebellar Development, Development of the Fish Cerebellum, the Role of nNOS/NO on Cerebellar Development in Health and Disease, and rehabilitation in cerebellar ataxia. The effect of the COVID-19 on the cerebellum has been included in related chapters. Development of the Cerebellum from Molecular Aspects to Diseases, 2nd edition, is designed to be valuable reference for both neuroscientists and clinicians.
    Materialart: Online-Ressource
    Seiten: IX, 639 p. 116 illus., 88 illus. in color. , online resource.
    Ausgabe: 2nd ed. 2023.
    ISBN: 9783031231049
    Serie: Contemporary Clinical Neuroscience,
    URL: https://doi.org/10.1007/978-3-031-23104-9
    DOI: 10.1007/978-3-031-23104-9
    DDC: 612.8
    Sprache: Englisch
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  • 17
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    Neuronal Oscillations of Wakefulness and Sleep : Windows on Spontaneous Activity of the Brain (2020)
    New York, NY :Springer New York :
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    Schlagwort(e): Neurosciences. ; Neurology . ; Neuroscience. ; Neurology.
    Beschreibung / Inhaltsverzeichnis: PART 1: WAKEFULNESS -- Chapter 1. Exploring Oscillations in Expert Sensorimotor Anticipation: the Tennis Return of Serve -- Chapter 2. Theta Rhythm in Hippocampus and Cognition -- Chapter 3. Oscillations and Synchrony in Attention -- Christian Keitel, Gregor Thut, and Joachim Gross -- Chapter 4. Pathological High-Frequency Oscillations in Mesial Temporal Lobe Epilepsy -- PART TWO: SLEEP -- Chapter 5. Cellular Mechanisms of Thalamocortical Oscillations in the Sleeping Brain -- Chapter 6. Neuroimaging of Brain Oscillations During Human Sleep -- Chapter 7. A Role for Neuronal Oscillations of Sleep in Memory and Cognition -- Chapter 8. Sleep Oscillations and Aging -- Chapter 9. Sleep Oscillations and Psychiatric Disorders.
    Kurzfassung: This edited volume reviews recent findings that highlight the mechanisms and functions of the neuronal oscillations that structure brain activity across the sleep-wake cycle. An increasing number of studies conducted in humans and animals use a variety of techniques, ranging from intracellular recording to functional neuroimaging, that provide important insight into the mechanisms and functional properties of these brain rhythms. This book explores how the studies of these rhythms are fundamental not only for basic neuroscience, but also for clinical neuroscience. At the basic science level, neuronal oscillations shape the interactions between different areas of the brain and profoundly impact neural responses to the environment, thereby mediating the processing of information in the brain. At the clinical level, brain oscillations are affected in numerous neurological conditions and might provide useful biomarkers that inform about patients’ evolution and vulnerability. During sleep, these brain rhythms could provide functional support to internal states that govern the basic maintenance of local circuit and systemic interactions. During wake, the rhythmicity of cortical and subcortical circuits have been linked with sensory processing, cognitive operations, and preparation for action.This volume attempts to link together these sleep and wake functional roles at the level of neuroimaging and electroencephalographic measures, local field potentials, and even at the cellular level. .
    Materialart: Online-Ressource
    Seiten: XXI, 277 p. 40 illus., 24 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9781071606537
    URL: https://doi.org/10.1007/978-1-0716-0653-7
    DOI: 10.1007/978-1-0716-0653-7
    DDC: 612.8
    Sprache: Englisch
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  • 18
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    Gregory Bateson on Relational Communication: From Octopuses to Nations (2020)
    Cham :Springer International Publishing :
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    Schlagwort(e): Psychobiology. ; Human behavior. ; Semiotics. ; Communication. ; Ethnology. ; Social sciences. ; Humanities. ; Behavioral Neuroscience. ; Semiotics. ; Media and Communication. ; Ethnography. ; Humanities and Social Sciences.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Bateson, Cybernetics, and Nonverbal Communication -- Chapter 2: Analog and Digital Communication, and Similar Contrasts -- Chapter3: The Slash Mark: Gregory Bateson’s Cybernetic Semiotic -- Chapter4: Intention Movements and Peacemaking Ceremonies -- Chapter5: Relational Communication in Octopus -- Chapter6: Cuban Missile Crisis -- Chapter7: False and True Lessons from the Cuban Missile Crisis -- Chapter8: A Level too Low.
    Kurzfassung: This book develops Gregory Bateson’s ideas regarding “communication about relationship” in animals and human beings, and even nations. It bases itself on Bateson’s theory of relational communication, as he described it in the zoosemiotics of octopus, mammals, birds, and human beings. This theory includes, for example, the roles of metaphor, play, analog and digital communication, metacommunication, and Laws of Form. It is organized around a letter from Gregory Bateson to his fellow cybernetic thinker Warren McCulloch at the time of the Cuban Missile Crisis. In this letter Bateson argued that what we would today call zoosemiotics, including Bateson’s own (previously unpublished) octopus research, should be made a basis for understanding the relationship between the two blocs of the Cold War. Accordingly the book shows how Bateson understood interactive processes in the biosemiotics of conflict and peacemaking, which are analyzed using examples from recent animal studies, from primate studies, and from cultural anthropology. The Missile Crisis itself is described in terms of Bateson’s critique of game theory which he felt should be modified by an understanding of the zoosemiotics of relational communication. The book also includes a previously unpublished piece by Gregory Bateson on wolf behavior and metaphor/ abduction.
    Materialart: Online-Ressource
    Seiten: XIX, 189 p. 7 illus. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030521011
    Serie: Biosemiotics, 20
    URL: https://doi.org/10.1007/978-3-030-52101-1
    DOI: 10.1007/978-3-030-52101-1
    DDC: 612.8
    Sprache: Englisch
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  • 19
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    Neuroendocrine Clocks and Calendars (2020)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Endocrine glands. ; Neuroscience. ; Endocrine System.
    Beschreibung / Inhaltsverzeichnis: Photoperiodism and Circannual Timing: Introduction and Historical Perspective.-The Pars Tuberalis and Seasonal Timing -- Tanycytes and Their Pivotal Role in Seasonal Physiological Adaptations -- Epigenetic Mechanisms in Developmental and Seasonal Programs -- Plasticity of Neuroendocrine Mechanisms Regulating Seasonal Reproduction in Sheep -- Clocks and Calendrars in Birds -- Calendar Timing in Teleost Fish -- Action of Light on the Neuroendocrine Axis -- Seasons, Clocks, and Mood -- Photoperiodic Modulation of Clock Gene Expression in the SCN -- Circadian Timekeeping in the Suprachiasmatic Nucleus: Genes, Neurotransmitters, Neurons and Astrocytes. .
    Kurzfassung: This book explores how daily and seasonal rhythmicity is generated, how these rhythms are synchronised by our environment, and how they regulate the neuroendocrine systems that impact our physiology and behaviour. The constraints of surviving in a seasonal environment have shaped human evolution and migration, have shaped our societies and cultures, and continue to influence our everyday lives, health and wellbeing. Identifying the mechanisms whereby seasonal rhythmicity is generated and regulates the brain and body is not only important for understanding the natural world and relevant to animal production, it also offers many insights into the human condition. Each chapter is written by an international expert in the field of chronobiology. A historical perspective on how research into photoperiodism and rhythmicity progressed is initially provided, but the main focus of this book is on the remarkable studies in the last few decades that have unravelled the molecular and cellular machinery underpinning circadian and circannual timing. Topics covered include the role of melatonin in communicating seasonal information to the brain and pituitary gland, the neuroanatomical pathways in mammals, birds and fish by which changes in photoperiod reach the hypothalamus, the role of glial cells (tanycytes) and thyroid hormone in seasonal rhythmicity, neuroplasticity across seasons, effects of changing day length on mood, regulation of “clock“ gene expression, and the role of the suprachiasmatic nucleus. This book will appeal to all students and researchers who wish to learn about current and past research on daily and seasonal rhythmicity. This is the tenth volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series (Volumes 1-7 published by Wiley) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology. .
    Materialart: Online-Ressource
    Seiten: XII, 244 p. 64 illus., 58 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030556433
    Serie: Masterclass in Neuroendocrinology, 10
    URL: https://doi.org/10.1007/978-3-030-55643-3
    DOI: 10.1007/978-3-030-55643-3
    DDC: 612.8
    Sprache: Englisch
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  • 20
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    Frontotemporal Dementias : Emerging Milestones of the 21st Century (2021)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Neurology . ; Medical genetics. ; Neuroscience. ; Neurology. ; Medical Genetics.
    Beschreibung / Inhaltsverzeichnis: 1. Behavioural variant FTD: recent advances in the diagnosis and understanding of the disorder -- 2. The neuropsychiatry of frontotemporal dementia -- 3. Nosology and Neuropathology of Language in Primary Progressive Aphasia -- 4. Measuring Behavior and Cognition in FTLD -- 5. Clinical update on C9orf72: FTD, ALS and beyond -- 6. Clinical aspects of familial FTLD associated with MAPT and GRN mutations -- 7. Neuroimaging in Frontotemporal Lobar Degeneration -- 8. The FTD Prevention Initiative - linking together genetic FTD cohort studies -- 9. Fluid Biomarkers of Frontotemporal Lobar Degeneration -- 10. Cross-cultural perspectives on frontotemporal degeneration -- 11. Clinical characteristics and Neuropathology of PSP, CBD and Related 4R-Tauopathies -- 12. Tau protein and frontotemporal dementias -- 13. FTLD-TDP pathological subtypes: clinical and mechanistic significance -- 14. Lysosomal dysfunction as a pathogenic mechanism in FTD: Evidence from PGRN and TMEM106B genetics and biology -- 15. Future trends in understanding the pathological role of TDP-43 and FUS proteins -- 16. Description of a new data resource for FTD including multiomic data on human post mortem brain (MAPT, GRN, C9orf72), matching mouse models and iPS models -- 17. Mendelian and sporadic FTD: avenues from genetics to disease pathways through in-silico prediction and modeling -- 18. FTLD treatment: Current Practice and Future Possibilities.
    Kurzfassung: Under the name of Frontotemporal Dementias (FTD) numerous hereditary and sporadic disorders are listed. FTD may take away speech and language, social skills and ethical judgement, wishes and will, empathy and emotions; it may also impair motor functions. FTD may affect men and women in midlife or during old age leading to the demolition of the uniqueness of the human mind. In the last decade of the 20th century and in the first two decades of the 21st century, progress in the understanding of clinical, neuropathological, biochemical, and genetic aspects of FTD has accelerated. The novel awareness about FTD has directed young generations of researchers toward the study of this complex group of disorders. This Volume has been formulated with the participation of some of the leading scientists who have contributed to the development of knowledge in the clinical and basic science arenas. It captures the current central elements that are relevant to an up-to-date understanding of causes and pathogenesis of multiple forms of FTD. The volume is an opus that represents a distillation of the work of many scientists and addresses the current directions in the study of one of the most complex groups of diseases. In view of its structure, the book could also be used as a textbook, that offers both a broad and deep analysis of major areas in FTD. This book, planned by the International Society for Frontotemporal Dementias, is distinctive as it opens a window to a wide landscape about the biology of FTD. Thus, the book represents a moment of reflection on the present state of our knowledge of FTD and a collective vision toward scientific progress. The authors of each chapter share their knowledge and vision aimed at reducing the suffering which is caused by FTD.
    Materialart: Online-Ressource
    Seiten: X, 320 p. 46 illus. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030511401
    Serie: Advances in Experimental Medicine and Biology, 1281
    URL: https://doi.org/10.1007/978-3-030-51140-1
    DOI: 10.1007/978-3-030-51140-1
    DDC: 612.8
    Sprache: Englisch
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  • 21
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    Current Thoughts on Dementia : From Risk Factors to Therapeutic Interventions (2022)
    Singapore :Springer Nature Singapore :
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    Schlagwort(e): Neurosciences. ; Zoology. ; Medical genetics. ; Biotechnology. ; Medicine Research. ; Biology Research. ; Neuroscience. ; Zoology. ; Medical Genetics. ; Biotechnology. ; Biomedical Research.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. ApoE: A Risk Factor for Dementia -- Chapter 2. Infection-Induced Systemic Inflammation and Dementia -- Chapter 3. Role of Impaired Insulin Signaling in the Pathogenesis of Dementia -- Chapter 4. Sex Hormones as Risk Factors of Dementia -- Chapter 5. Mitophagy Impairments as Culprit of Alzheimer’s Disease -- Chapter 6. Parkinson’s Disease: Neurochemistry and Pharmacological Treatment -- Chapter 7. Emerging Roles of TREM2 in Neurodegenerative Diseases -- Chapter 8. Molecular Mechanisms Underlying the Role of HSPB8 in Neurodegeneration -- Chapter 9. Molecular Insights into the Role of ER Stress in Neurodegenerative Diseases. Chapter 10. Role of Hypertension and Hyperlipidemia in the Pathogenesis of Dementia -- Chapter 11. Behavioral Abnormalities of Gut Microbiota and Progression of Dementia -- Chapter 12. Gut-Brain Axis in Alzheimer's Disease: Interplay between Cholecystokinin, Dysbiosis, and Brain-Derived Neurotrophic Factor -- Chapter 13. Cholesterol and Dementia: A Possible Therapeutic Approach -- Chapter 14. Therapeutic Potential of PPARs in Alzheimer’s Disease -- Chapter 15. Exploring the Role of Statins in Reversing the Cognitive and Neurovascular Dysfunctions in Dementia -- Chapter 16. Role of Immunotherapy in Ameliorating Proteopathic Dementia -- Chapter 17. Hypoxic-Hyperoxic Training in Dementia -- Chapter 18. Music Therapy in Dementia -- Chapter 19. Beneficial Effects of Citrus Flavonoids against Aβ Pathology in Alzheimer’s Disease -- Chapter 20. Therapeutic Potential of Phytochemicals: Lessons Learned from Streptozotocin-Induced Sporadic Alzheimer’s Disease -- Chapter 21. Concept of Amnesia and Dementia in Unani System of Medicine -- Chapter 22. Nanotechnological Applications in the Diagnosis and Treatment of Alzheimer’s Dementia.
    Kurzfassung: This informative book discusses the latest research on the risk factors and therapeutics in dementia. WHO calls dementia a public health priority. Dementia manifests as a group of symptoms associated with decline in memory or other thinking skills and is severe enough to reduce a person's ability to perform everyday activities. It occurs frequently among elderly people, but it is not necessarily part of the normal aging process. The book has been divided into two broad sections. The first section reviews the risk factors involved in developing dementia, including various medical conditions, lifestyle choices, as well as genetics. The latter section describes various therapeutic interventions in dementia. Although there is no known cure for dementia, this book underlines the current treatment strategies that could momentarily reduce the symptoms and improve the quality of life of the patients. This book highlights the global effort to find better ways to halt the progression of dementia and develop novel therapeutic strategies. The book would be an interesting read for advanced graduate students and researchers working in the field of neuroscience, genetics, and medicine. It will generate good interest to neurologists, psychiatrists, geriatricians, cardiologists, internal medicine practitioners, epidemiologist, and public health workers.
    Materialart: Online-Ressource
    Seiten: XV, 624 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811676062
    URL: https://doi.org/10.1007/978-981-16-7606-2
    DOI: 10.1007/978-981-16-7606-2
    DDC: 612.8
    Sprache: Englisch
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  • 22
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    Online-Ressource
    Regenerative Therapies in Ischemic Stroke Recovery (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Neurosciences. ; Stem cells. ; Nervous system Regeneration. ; Neuroscience. ; Stem Cell Biology. ; Regeneration and Repair in the Nervous System.
    Beschreibung / Inhaltsverzeichnis: 1 Regenerative Therapies in Ischemic Stroke Recovery -- 2 Application of Nanotechnology In Stroke Recovery -- 3 Nanotechnology: A daydream for advanced Imaging, Diagnosis and Therapeutic Approach for Cerebral Ischemia -- 4 Cell-Mediated Neurorestorative Mechanisms Underpinning Beneficial Effects in Ischemic Stroke -- 5 Induced Pluripotent Stem Cells for the Treatment of Neurodegenerative Disease: Current and Future Prospects -- 6 Imaging of Stem Cell Therapy for Stroke and Beyond -- 7 Nano-Medicine Mediated Stem Cell Therapeutics In Stroke -- 8 The Influence of Preconditioning on the Homing Behaviour of Stem Cells -- 9 Role of microRNAs in stroke pathology and recovery -- 10 Exosomes as a diagnostic tool and stem cells exosomes as a promising cell-based cell-free therapeutic tool for ischemic stroke 11 Role of nanomedicine in treating ischemic stroke -- 12 Insights into therapeutic targets in stroke -- 13 Signalling Pathways of Interest for Recovery from Ischemic Stroke.
    Kurzfassung: This book illustrates the importance and significance of regenerative medicine in stroke recovery. It discusses stem-cell-based treatment strategies and offers mechanistic insights into their role in neurological recovery. It also examines the challenges and advances in using adult stem cells for enhanced therapeutic efficacy. Further, it presents the strategies as well as the strengths and weaknesses of various delivery methods to administer stem cells in ischemic stroke. It examines the role of non-coding RNA in our understanding the stroke pathogenesis, their regulatory role in ischemic stroke and potential as biomarkers and therapeutic targets. Lastly, it explores exosomes in the treatment of stroke, and the underlying mechanism of their action as therapeutic vectors for stroke. Given its scope, it is an excellent resource for neurologists, neuroscientists and researchers involved in regenerative therapy for stroke.
    Materialart: Online-Ressource
    Seiten: XIII, 353 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811685620
    URL: https://doi.org/10.1007/978-981-16-8562-0
    DOI: 10.1007/978-981-16-8562-0
    DDC: 612.8
    Sprache: Englisch
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  • 23
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    Online-Ressource
    Advances in Cognitive Neurodynamics (VII) : Proceedings of the Seventh International Conference on Cognitive Neurodynamics – 2019 (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Neurosciences. ; Biotechnology. ; Cognitive psychology. ; Nonlinear Optics. ; Neuroscience. ; Biotechnology. ; Cognitive Psychology. ; Nonlinear Optics.
    Beschreibung / Inhaltsverzeichnis: Neural Dynamics in Motor and Sensory Systems and in Cognitive Functions -- Cognitive Network and Multi-Scale Neural Network Dynamics -- Neuroengineering, Neuroinformation and Brain Computer Interaction -- Modelling Higher-Order Functions and Dysfunctions -- Oscillation, Synchronization, Neural Plasticity, and Coordination Dynamics from Neural to Social Systems.
    Kurzfassung: This book contains original articles submitted to the Seventh International Conference on Cognitive Neurodynamics (ICCN 2019). The brain is an endless case study of a complex system characterized by multiple levels of integration, multiple time scales of activity, and multiple coding and decoding properties. The contribution of several disciplines, mathematics, physics, computer science, neurobiology, pharmacology, physiology, and behavioral and clinical sciences, is necessary in order to cope with such seemingly unattainable complexity that transforms the experimental information into a tricky puzzle which hides the correspondence with model predictions. This conference gathered active participants to discuss ideas and pose new questions from different viewpoints, ranging from single neurons and neural networks to animal/human behavior in theoretical and experimental studies. The conference is organized with plenary lectures, mini-symposia, interdisciplinary round tables, and oral and poster sessions.
    Materialart: Online-Ressource
    Seiten: XIX, 293 p. 97 illus., 71 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811603174
    Serie: Advances in Cognitive Neurodynamics,
    URL: https://doi.org/10.1007/978-981-16-0317-4
    DOI: 10.1007/978-981-16-0317-4
    DDC: 612.8
    Sprache: Englisch
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  • 24
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    Online-Ressource
    The Social Impulse : The Evolution and Neuroscience of What Brings Us Together (2022)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Cognitive neuroscience. ; Social evolution. ; Neuroscience. ; Cognitive Neuroscience. ; Social Evolution.
    Beschreibung / Inhaltsverzeichnis: Part I Differentiation-Integration Dynamics: Ultimate Causes -- Chapter 1: Introduction -- Chapter 2: Purposeless Design -- Chapter 3: Darwinian Evolutionary Theory -- Chapter 4: Principles of Differentiation and Integration -- Chapter 5: The Information Trend in Science -- Chapter 6: Is Social Cohesion a Different Mechanism of Evolution? -- Part II Roots and Mechanisms: Proximate Causes -- Chapter 7: Fundamental Physical Forces, Genes, and Epigenetics -- Chapter 8: Biological Origins -- Chapter 9: Neural Mechanisms of Sociality -- Chapter 10: Psychological Features -- Chapter 11: Cognitive Science Underpinnings -- Chapter 12: A Sociological Systems Theory -- Chapter 13: Developmental Roots -- Chapter 14: Metaphysical, Religious, and Spiritual Aspects -- Part III Survival Value -- Chapter 15: Sociality’s Survival Value -- Part IV Conclusions -- Chapter 16: A New Framework: A Theory of Integration.
    Kurzfassung: This book is an exploration of the integration-differentiation dynamics that result in a drive, or impulse, toward human sociality, arguing that our need to connect with other people is as fundamental as our need for food and shelter. In The Social Impulse: The Evolution and Neuroscience of What Brings Us Together, Jaime Pineda presents the evidence that social cohesion is a complementary force to natural selection, the Darwinian drive for differentiation and diversity. The book addresses the distinctive aspects of social behavior that arise from integration principles and seeks to answer the following questions: (1) Why does social cohesion arise? (2) What is the history of social dynamics? (3) How does social cohesion work? (4) When do the developmental aspects of social dynamics arise? A final section of the book addresses the value of sociality and social cohesion. By exploring the differences, similarities, and, most important, the interactivity between natural selection and social cohesion, this unique book provides a wealth of interesting, challenging, and unexpected insights.
    Materialart: Online-Ressource
    Seiten: XXV, 190 p. 7 illus., 6 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031084393
    URL: https://doi.org/10.1007/978-3-031-08439-3
    DOI: 10.1007/978-3-031-08439-3
    DDC: 612.8
    Sprache: Englisch
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  • 25
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    Meanings of Pain : Volume 3: Vulnerable or Special Groups of People (2022)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Pain medicine. ; Clinical psychology. ; Neuroscience. ; Pain Medicine. ; Clinical Psychology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Conceptualising Pain in Critically-Ill Neonates or Infants -- Chapter 2. Pain in the Fetus and the Preterm Baby -- Chapter 3. Developmental Influences on the Meanings of Pain in Children -- Chapter 4. “Ooh, You Got to Holler Sometime:” Pain Meaning and Experiences of Black Older Adults -- Chapter 5. Exploring the Meaning of Chronic Low Back Pain as a Life of ‘Living Death’ in Rural Nigeria -- Chapter 6. Painworld: A Phenomenological View of Veteran Experiences of Living with Chronic Pain -- Chapter 7. “It’s Just One of Them Things You’ve Got to Try and Manage”: Meanings of Pain for People with Brain Injury.
    Kurzfassung: This book, the third and final volume in the Meaning of Pain series, describes what pain means to people with pain in “vulnerable” groups, and how meaning changes pain – and them – over time. Immediate pain warns of harm or injury to the person with pain. If pain persists over time, more complex meanings can become interwoven with this primitive meaning of threat. These cognitive meanings include thoughts and anxiety about the adverse consequences of pain. Such meanings can nourish existential sufferings, which are more about the person than the pain, such as loss, loneliness, or despair. Although chronic pain can affect anyone, there are some groups of people for whom particular clinical support and understanding is urgently needed. This applies to “vulnerable” or “special” groups of people, and to the question of what pain means to them. These groups include children, women, older adults, veterans, addicts, people with mental health problems, homeless people, or people in rural or indigenous communities. Several chapters in the book focus on the lived experience of pain in vulnerable adults, including black older adults in the US, rural Nigerians, US veterans, and adults with acquired brain injury. The question of what pain experience could mean in the defenceless fetus, neonate, pre-term baby, and child, is examined in depth across three contributions. This book series aspires to create a vocabulary on the “meanings of pain” and a clinical framework with which to use it. It is hoped that the series stimulates self-reflection about the role of meaning in optimal pain management. Meanings of Pain is intended for people with pain, family members or caregivers of people with pain, clinicians, researchers, advocates, and policy makers. Volume I was published in 2016; Volume II in 2019.
    Materialart: Online-Ressource
    Seiten: VII, 147 p. 5 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030958251
    URL: https://doi.org/10.1007/978-3-030-95825-1
    DOI: 10.1007/978-3-030-95825-1
    DDC: 612.8
    Sprache: Englisch
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  • 26
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    Neuroinflammation, Gut-Brain Axis and Immunity in Neuropsychiatric Disorders (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Neurosciences. ; Immunology. ; Physiology. ; Neuropsychology. ; Psychiatry. ; Neuroscience. ; Immunology. ; Physiology. ; Neuropsychology. ; Psychiatry.
    Beschreibung / Inhaltsverzeichnis: 1.How Immune-inflammatory processes link neurodegenerative and psychiatric disorders -- 2.Gut-Microbiota-Brain Axis: pathophysiological mechanism in neuropsychiatric disorders -- 3.Microbiome- induced autoimmunity and novel therapeutic intervention -- 4.The key role of microlia and circulating monocytes in etipathology neuropsychiatric disorders -- 5.Neuro-immuno-epigenetics of prenatal psychological stress -- 6.C-reactive protein (CRP): a potent inflammation biomarker in psychiatric disorders -- 7.Neuroinflammation, neurognesis and neuroprotection in schizophrenia -- 8.Autoimmue psycosis: concept, clinical manifestation and management -- 9.Stress, autonomic nervous system and kynurenine pathway in major depression -- 10.Brain-gut-microbiome axis in major depression : novel therapeutic approach -- 11.Glial-Neuronal Interaction in Synapses: A Possible Mechanism of the Pathophysiology of Bipolar Disorder -- 12.Neuroimmaging of inflammation in depression and anxiety disorders -- 13.Neuroinflammation and immune-kynureinine pathway in anxiety disorders -- 14.Inflammatory-mediated responses in development of neurogeneartive diseases -- 15.The connection between gut-brain axis and PTSD -- 16.Eating disorders : Gut microbiota-immune-brain interactions -- 17.Sleep-immune crosstalk and sleep disorders -- 18.Obsessive-compulsive disorder: immuno-inflammatory disorder? -- 19.Cytokine, neuroinflammation and neurodeneration in Alzheimer’s disease -- 20.Molecular imaging of neuroinflammation in Alzheimer's disease and MCI -- 21.The role of N-Methyl-D-Aspartate Receptor Neurotransmission and mictobiota in Alzheimer’s disease -- 22.Neuroglial activation and neuroinflammation in the brain of patients with autism -- 23.Suicide and inflammation -- 24.Anti-inflammatory effect of Traditional Chinese Medicine on the concept of Mind-body interface -- 25.Anti-inflammatory therapy as a promising target in neupsychiatric disorders.
    Kurzfassung: This book reviews the relationship between cytokines, glia, and neurons in the pathophysiology of neuropsychiatric disorders and examines the mechanisms of action of the drugs used for the treatment of these disorders. Increasing evidence has suggested that glia perform important roles in various brain functions, but much remains to be learned about these crucial cells and their interplay with neurons. In addition, a better understanding of the interaction between inflammatory mediators, such as cytokines, and the activated immune response will be of critical importance for the development of new therapeutic strategies. These key areas are the focus of this book, which documents the latest research findings in the field. Evidence is provided for the role of inflammation-induced toxic metabolites from the tryptophan pathway in a wide range of neuropsychiatric disorders, including depression, schizophrenia, and Alzheimer's disease. In presenting state of the art knowledge on the interactions between cytokines, glia, and neurons, the book will help to pave the way for the development of novel targets for the prevention and treatment of neuropsychiatric disorders.
    Materialart: Online-Ressource
    Seiten: XVII, 554 p. 28 illus., 20 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789811973765
    Serie: Advances in Experimental Medicine and Biology, 1411
    URL: https://doi.org/10.1007/978-981-19-7376-5
    DOI: 10.1007/978-981-19-7376-5
    DDC: 612.8
    Sprache: Englisch
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  • 27
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    Visceral Pain (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Neurophysiology. ; Gastroenterology. ; Neuroscience. ; Neurophysiology. ; Gastroenterology.
    Beschreibung / Inhaltsverzeichnis: Tools for optogenetic probing of nociceptive pathways; Monitoring activity -- An open science model to accelerate the generation, implementation and distribution of optogenetics and viral tools -- Vagal neuroinflammation accompanying respiratory viral infection: An overview of mechanisms and possible clinical significance -- Stress-induced Visceral Analgesia: Concept and Pathways -- Evidence of early life stress exposure and epigenetic modifications in functional chronic pain disorders -- EPIGENETIC REGULATION OF STRESS-INDUCED VISCERAL PAIN -- The biomechanics and mechanotransduction in visceral nociception -- VISCERAL NOCICEPTION IN GASTROINTESTINAL DISEASE -- Epithelial-Neuronal Communication in Visceral Pain -- Physiological Mechanisms Underpinning Heightened Perception of Visceral Afferent Signalling in Irritable Bowel Syndrome -- A fentanyl analogue that activates u-opioid receptors in acidified tissues inhibits colitis pain without opioid side effects -- Signalling in the Gut -- Translating colonic sensory afferent peripheral mechanosensitivity into the spinal cord dorsal horn -- Translating colonic afferent peripheral sensitivity into the spinal cord dorsal horn -- Neuron-Microglia Dynamic Duo in Chronic Abdominal Pain -- Pre-clinical Models of Endometriosis -- Spinal afferent innervation of the uterus -- Post-infectious bladder hypersensitivity in the development of Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS).
    Kurzfassung: The chapters in this book are based on the Visceral Pain conference in Adelaide, Australia, under the auspices of the International Federation for Neurogastroenterology and Motility in 2021. This is one of the hottest fields of science and includes mechanisms involving how the microbiome communicates with the brain and how, when disordered, these mechanisms contribute to clinical diseases such as Irritable Bowel Syndrome and Inflammatory Bowel Disease. Researchers from around the globe presented their latest findings as a review of the current state of the art in the field from both the clinical and scientific points of view. These systems are now appreciated as being critical for shaping our well-being and their disorders underlie chronic clinical conditions of significant morbidity and mortality. The author team includes long-established authorities who significantly contributed to the advances in visceral pain research over the past two decades and the new generation that will continue to contribute to advancing our understanding of the field.
    Materialart: Online-Ressource
    Seiten: VIII, 255 p. 37 illus., 33 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031257025
    URL: https://doi.org/10.1007/978-3-031-25702-5
    DOI: 10.1007/978-3-031-25702-5
    DDC: 612.8
    Sprache: Englisch
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  • 28
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    Advances in Brain Imaging Techniques (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Neurosciences. ; Materials Analysis. ; Imaging systems. ; Nervous system Diseases. ; Nervous system Radiography. ; Neuroscience. ; Imaging Techniques. ; Neurological Disorders. ; Neuroradiology.
    Beschreibung / Inhaltsverzeichnis: Optical coherence tomography in brain gliomas detection and peritumoral white matter state evaluation -- Two Photon Fluorescence Lifetime Imaging of Reduced nicotinamide adenine dinucleotide in Brain Research -- Types of Raman Scattering Techniques for Neurodegenerative Diseases -- Drosophila brain advanced multiphoton imaging -- Myelin imaging -- Brainbow: Principle, Technique and Applications -- Photoacoustic Imaging of Brain -- Photodynamic therapy of brain diseases -- Advanced Magnetic Resonance Imaging (MRI) of Brain -- Indirect imaging -- Multimodal Noninvasive Imaging Strategies for Clinically Monitoring Degenerative Disorders of the Brain -- Machine learning approach in brain imaging -- Transgenic Brain mapping Techniques in Drosophila melanogaster -- Behavioural phenotyping to study cognitive and non-cognitive symptoms in the rodent model of Alzheimer's disease.
    Kurzfassung: The book reviews the recent developments in brain imaging and their technological advancements to understand molecular mechanisms associated with neurological disorders and basic behaviors in humans and rodents at the structural, molecular, and functional levels. It discusses the usefulness of advanced optical microscopy techniques, including optical coherence tomography (OCT), miniscope, multiphoton fluorescence (2PF & 3PF), adaptive optics, harmonic generation, and Raman microscopy for understanding pathomechanism of brain disorders and pathological and physiological changes associated with neurodegenerative diseases. Also, the book presents conventional imaging modalities, including Magnetic Resonance Imaging (MRI), for delineating underlying mechanisms and precise early diagnosis of neurological disorders. This book is a useful resource for neuroscientists and researchers working in biomedical engineering and optics.
    Materialart: Online-Ressource
    Seiten: XII, 257 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811913525
    URL: https://doi.org/10.1007/978-981-19-1352-5
    DOI: 10.1007/978-981-19-1352-5
    DDC: 612.8
    Sprache: Englisch
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  • 29
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    Online-Ressource
    Sex Differences in Brain Function and Dysfunction (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Neuropsychology. ; Psychiatry. ; Neuroscience. ; Neuropsychology. ; Psychiatry.
    Beschreibung / Inhaltsverzeichnis: Part 1: Considering sex and gender in research studies -- Sex and Gender Science -- Best practices in the study of sex? -- Best practices in the study of Gender Differences -- The special case of a lack of sex differences – the naked mole rat? -- Lateralization and -- Part 2: Sex differences in cognitive and mental health across the lifespan -- Depression -- Schizophrenia -- Immune and neurodevelopmental disorders – autism? -- Social Cognition -- Cognition and cognitive ageing -- Part 3: Diseases of the brain and relevance of sex -- Epilepsy -- Stroke -- AD -- Parkinson’s -- Multiple Sclerosis.
    Kurzfassung: Does sex matter when it comes to brain function? This volume attempts to answer this very important question which is of relevance to the disciplines of psychology, neuroscience, psychiatry and neurology. Understanding how brain function and resultant behaviors may differ between the sexes impacts upon our knowledge of the pathology and development of treatments for various neurological and psychiatric disorders, particularly those that show significant sex differences in either prevalence and/or manifestation of symptoms. This volume covers three main themes of research into sex differences in basic neurobiology, psychology, preclinical research and clinical research. It begins by exploring our understanding of sex and gender in relation to both animal and human behaviors and discusses the relevance, and importance, of considering sex and gender when conducting research into brain function and behaviors. The second theme focuses on how sex and gender influence mental health and considers the impact of our immune system and the changes that occur with ageing. Finally, the third aspect focuses on examples of neurological disorder which show sex differences in terms of their aetiology and/or symptomology and considers the relevance in the development of treatment for these disorders including dementia, stroke and multiple sclerosis. This volume is of considerable interest to mental health and neurology professionals, including psychiatrists, neurologists, nurses, allied health clinicians and pharmacists. It is also helpful and important for preclinical researchers working in neuroscience, psychopharmacology and reproductive endocrinology.
    Materialart: Online-Ressource
    Seiten: X, 373 p. 70 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031267239
    Serie: Current Topics in Behavioral Neurosciences, 62
    URL: https://doi.org/10.1007/978-3-031-26723-9
    DOI: 10.1007/978-3-031-26723-9
    DDC: 612.8
    Sprache: Englisch
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  • 30
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    Trials for Cerebellar Ataxias : From Cellular Models to Human Therapies (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Neurology . ; Pharmaceutical chemistry. ; Cognitive neuroscience. ; Neuroscience. ; Neurology. ; Pharmaceutics. ; Cognitive Neuroscience.
    Beschreibung / Inhaltsverzeichnis: Part I: Basic Science of Cerebellum and Ataxias -- Functional anatomy of the cerebellum -- Cerebellar physiology -- Cerebellar biochemistry/pharmacology -- Genetics of dominant ataxias -- Autosomal and X-linked degenerative ataxias: from genetics to promising therapeutics -- Seeking therapies for Spinocerebellar Ataxia: from gene silencing to systems-based approaches -- Ion Channel Genes and Ataxia -- Part II: Biomarkers and tools of trials -- How to Design a Therapeutic Trial in SCAs -- Therapy development for spinocerebellar ataxia: Rating Scales and Biomarkers -- Clinical rating scales for ataxia -- Scale for Ocular motor Disorders in Ataxia (SODA): Procedures and Basic Understanding -- Cerebellar learning in the prism adaptation task -- Blood and CSF biomarkers in autosomal dominant cerebellar ataxias -- Part III: Autosomal Dominant Cerebellar Ataxias -- Riluzole in progressive cerebellar ataxias -- ASOs against ATXN2 in preclinical and phase 1 trials -- Antisense oligonucleotide therapy against SCA3 -- Spinocerebellar ataxia type 7: From mechanistic pathways to therapeutic opportunities -- Experimental neurotransplantation for cerebellar ataxias -- Development of mesenchymal stem cells therapy for the treatment of polyglutamine SCA: from bench to bedside -- Cerebello-Spinal tDCS as Rehabilitative Intervention in Neurodegenerative Ataxia -- Cerebellar Transcranial Magnetic Stimulation in Cerebellar Ataxias -- Physical therapy in Cerebellar Ataxia -- Part IV: Autosomal Recessive Cerebellar Ataxias -- Recent advances on therapeutic approaches for Friedreich’s Ataxia -- Therapeutic use of interferon gamma in Friedreich ataxia -- Metabolic treatments of cerebellar ataxia -- Clinical Trials in Fragile X-Associated Tremor/Ataxia Syndrome -- Part V: Sporadic Ataxias -- Therapeutic strategies in immune-mediated cerebellar ataxias -- Coenzyme Q10 in MSA -- State of the Art and History of Therapeutics in Ataxias.
    Kurzfassung: Despite the critical importance of the cerebellum in brain functions, the scientific community still lacks effective treatments for most cerebellar ataxias. This book provides a link between the pathogenesis and therapies of cerebellar ataxias while also providing a comprehensive assessment of the preclinical and clinical trials dedicated to cerebellar ataxias over the past 20 years of progress. This is the first book fully dedicated to the trials and therapies of these disorders. It is a truly authoritative and comprehensive reference and comes at a time of major advances in genetic tools and neuroimaging assessments. The coverage begins by laying a foundation of the basic science of the cerebellum and ataxias, proceeds to discuss biomarkers and the tools of trials, offers guidelines on conducting trials, and then explores the full range of therapeutics and their trials, including gene therapy and cell transplantation. The authors are top experts on cerebellar research and the contributing authors have all made seminal contributions in the field.
    Materialart: Online-Ressource
    Seiten: XI, 727 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031243455
    Serie: Contemporary Clinical Neuroscience,
    URL: https://doi.org/10.1007/978-3-031-24345-5
    DOI: 10.1007/978-3-031-24345-5
    DDC: 612.8
    Sprache: Englisch
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  • 31
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    Astrocytes in Psychiatric Disorders (2021)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Nervous system Diseases. ; Neurology . ; Neurophysiology. ; Neuropsychology. ; Neurons. ; Neuroscience. ; Neurological Disorders. ; Neurology. ; Neurophysiology. ; Neuropsychology. ; Cellular Neuroscience.
    Beschreibung / Inhaltsverzeichnis: Introduction: Neuroglia in psychiatric disorders -- Chapter 1. Astrocytes: The housekeepers and guardians of the CNS -- Chapter 2. Principles of astrogliopathology -- Chapter 3. Morphological appearance of astroglia in neuropsychiatric disorders -- Chapter 4. Astrocytes and neurotransmission: Glutamate and GABA in cognitive and mood disorders -- Chapter 5. Astroglia in bipolar disorder -- Chapter 6. Astroglia abnormalities in mood disorders -- Chapter 7. Astroglia in major depression and suicide -- Chapter 8. Neuroglia in Schizophrenia -- Chapter 9. Glutamate turnover in Schizophrenia -- Chapter 10. Astroglia and dopanime transmission in Schizophrenia -- Chapter 11. Kynurenic acid in Schyzophrenia -- Chapter 12. Astrocytes in addictive disorders -- Chapter 13. Astroglia in the vulnerability and maintenance of alcohol dependence -- Chapter 14. Astroglia in response to stress -- Chapter 15. Astroglia and Obsessive compulsive disorder -- Chapter 16. Astrocytes in regulation of food intake -- Chapter 17. Astrocytes in anorexia nervosa -- Chapter 18. Astroglial serotonin receptors as the central target of classic antidepressants -- Chapter 19. Lithium targets astrocytes -- Epilogue.
    Kurzfassung: This contributed volume discusses the multiple roles of astrocytes, which determine the progression and outcome of neuropsychiatric diseases. This emerging area of study examines the ways in which astrocytes are involved in various aspects of disease initiation, progression and resolution. This monograph aims to integrate the body of information that has accumulated in recent years revealing the active role of astrocytes in neuropsychiatric pathology and in psychiatric disorders. Understanding roles of astrocytes in pathology will provide new targets for medical intervention and aid the development of much needed therapeutics. This book will be valuable for researchers and workers in the fields of neurobiology, neurology, and psychiatry, as well as fill the need for a textbook used in advanced courses/graduate seminars in glial pathophysiology.
    Materialart: Online-Ressource
    Seiten: VI, 377 p. 36 illus. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030773755
    Serie: Advances in Neurobiology, 26
    URL: https://doi.org/10.1007/978-3-030-77375-5
    DOI: 10.1007/978-3-030-77375-5
    DDC: 612.8
    Sprache: Englisch
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  • 32
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    Neurobiological and Psychological Aspects of Brain Recovery (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Neuropsychology. ; Neurology . ; Neuroscience. ; Neuropsychology. ; Neurology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Understanding the Mechanisms of Dendritic Arbor Development: Integrated Experimental and Computational Approaches -- Chapter 2: Autophagy Mechanisms for Brain Recovery. Keep It Clean, Keep It Alive -- Chapter 3: Environmental enrichment and functional plasticity in the hippocampus, an update on the mechanisms involved -- Chapter 4: Translatable Models of Brain and Cognitive Reserve -- Chapter 5: Cognitive Reserve: A Life-Course Perspective -- Chapter 6: Neural Correlates of Brain Reserve: A Neuroimaging Perspective -- Chapter 7: Non-pharmacological Approaches Based on Mind-Body Medicine to Enhancement of Cognitive and Brain Reserve in Humans -- Chapter 8: Roles of Synaptic Plasticity in Functional Recovery After Brain Injury -- Chapter 9: Integrated Methods of Neuromodulation for Guiding Recovery Following Stroke -- Chapter 10: Resilience in Brain Networks After Stroke -- Chapter 11: Epigenetics and brain plasticity: back to function -- Chapter 12: Functional Role of Physical Exercise and Omega-3 Fatty Acids on Depression and Mood Disorders -- Chapter 13: BRAIN RECOVERY IN CHILDHOOD: THE INTERACTION BETWEEN DEVELOPMENTAL PLASTICITY AND REGENERATIVE MECHANISMS -- Chapter 14: Estrogen Neuroprotective Activity After Stroke and Spinal Cord Injury -- Chapter 15: Making Meaning of Acquired Brain Injury: Resources for Functional Recovery -- Chapter 16: An Update on Premorbid Personality Traits and Brain Recovery - Another Aspect of Resilience -- Chapter 17: Psychological Aspects of Recovery After Brain Injury: A Focus on Psychodynamic Factors -- Chapter 18: Artificial Intelligence applications for Traumatic Brain Injury research and clinical management.
    Kurzfassung: The importance of this unique book's approach lies in addressing the impact of neurobiological factors as well as psychological influences on brain recovery following injury. There is growing evidence that emotional, motivational, and cognitive factors along with personality traits play a crucial role in brain plasticity, resilience, and recovery. Topics include synaptic and neuronal plasticity, development of brain reserves, biological markers, environmental factors, emotional resilience, and personality traits. By combining the latest research on neural mechanisms and psychological resilience the authors present a book that will help lead to the development of better treatment strategies for functional recovery from brain damage. The new edition is fully updated throughout and contains completely new chapters on brain recovery in childhood, epigenetic aspects of brain recovery, and artificial intelligence techniques in traumatic brain injury research.
    Materialart: Online-Ressource
    Seiten: XXIV, 406 p. 1 illus. , online resource.
    Ausgabe: 2nd ed. 2023.
    ISBN: 9783031249303
    Serie: Contemporary Clinical Neuroscience,
    URL: https://doi.org/10.1007/978-3-031-24930-3
    DOI: 10.1007/978-3-031-24930-3
    DDC: 612.8
    Sprache: Englisch
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  • 33
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    Speech Perception (2022)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Neuroscience.
    Beschreibung / Inhaltsverzeichnis: 1. The Auditory Cognitive Neuroscience of Speech Perception in Context -- 2. Subcortical Processing of Speech Sounds -- 3. Cortical Representation of Speech Sounds: Insights from Intracranial Electrophysiology -- 4. A Parsimonious Look at Neural Oscillations in Speech Perception -- 5. Extracting Language Content From Speech Sounds: The Information Theoretic Approach -- 6. Speech Perception under Adverse Listening Conditions -- 7. Adaptive Plasticity in Perceiving Speech Sounds -- 8. Development of Speech Perception -- 9. Interactions Between Audition and Cognition in Hearing Loss and Aging.
    Kurzfassung: This volume reviews contemporary developments in the auditory cognitive neuroscience of speech perception, including both behavioral and neural contributions. It serves as an important update on the current state of research in speech perception. The Auditory Cognitive Neuroscience of Speech Perception in Context Lori L. Holt, and Jonathan E. Peelle Subcortical Processing of Speech Sounds Bharath Chandrasekaran, Rachel Tessmer, and G. Nike Gnanateja Cortical Representation of Speech Sounds: Insights from Intracranial Electrophysiology Yulia Oganian, Neal P. Fox, and Edward F. Chang A Parsimonious Look at Neural Oscillations in Speech Perception Sarah Tune, and Jonas Obleser Extracting Language Content From Speech Sounds: The Information Theoretic Approach Laura Gwilliams, and Matthew H. Davis Speech Perception under Adverse Listening Conditions Stephen C. Van Hedger, and Ingrid S. Johnsrude Adaptive Plasticity in Perceiving Speech Sounds Shruti Ullas, Milene Bonte, Elia Formisano, and Jean Vroomen Development of Speech Perception Judit Gervain Interactions Between Audition and Cognition in Hearing Loss and Aging Chad S. Rogers, and Jonathan E. Peelle .
    Materialart: Online-Ressource
    Seiten: XVI, 252 p. 33 illus., 29 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030815424
    Serie: Springer Handbook of Auditory Research, 74
    URL: https://doi.org/10.1007/978-3-030-81542-4
    DOI: 10.1007/978-3-030-81542-4
    DDC: 612.8
    Sprache: Englisch
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  • 34
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    Glial-Neuronal Signaling in Neuroendocrine Systems (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Neurosciences. ; Anatomy. ; Internal medicine. ; Neuroscience. ; Anatomy. ; Internal Medicine.
    Beschreibung / Inhaltsverzeichnis: PART I. Glial-Neuronal Interactions in the Control of Hypothalamic Development -- The Role of Microglia in the Developing Hypothalamus -- PART II. Glial-Neuronal Interactions in the Control of the Magnocellular Neuroendocrine System -- Functional Consequences of Morphological Plasticity in the Adult Hypothalamo-Neurohypophysial System -- Fenestrated Capillary and Dynamic Neuro-Glial-Vascula Reorganization of the Adult Neurohypophysis -- Astrocyte-Magnocellular Neuron Interactions in Hypothalamic Memory -- The Multifaceted Roles of Hypothalamic Astrocytes and Microglial Cells in Neuroendocrine and Autonomic Regulation in Health and Disease -- PART III. Gial-Neuronal Interactions in the Control of Metabolic Function -- Control of Systemic Metabolism by Astrocytes in the Brain -- Glia-Neuron Communication: Not a One-way Street -- PART IV. Glial-Neuronal Interactions in the Control of the Stress Response -- Retrograde Signaling Via Dendritic Activation of Glial-Neuronal Circuits -- PART V. Glial-Neuronal Interactions in the Control of Reproductive Function -- Microglia, Hormones, and Behavior -- Hypothalamic Astrocytes and the Role of Neuroprogesterone in Estrogen Positive Feedback -- PART VI. Glial-Neuronal Interactions that Link Brain and Periphery -- Unveiling the Importance of Tanycytes in the Control of the Dialogue Between the Brain and the Periphery -- Tanycyte Regulation of Hypophysiotropic TRH Neurons.
    Kurzfassung: This volume discusses current research on glial-neuronal interactions in several neuroendocrine systems. Glial-neuronal bidirectional transmission represents one of the fastest-growing areas of investigation in neuroscience today. Unraveling the interactions and signaling synergy between glial cells and neurons is critical to advancing our understanding of brain function. Consequently, this book summarizes the latest findings on the roles of astrocytes, microglia and tanycytes in the control of synaptic transmission, synaptic plasticity, blood-brain signaling, neuroinflammation and immune signaling. In addition, leading experts in the field discuss how reproductive function, the stress response and energy homeostasis are regulated by glial-neuronal communication. Given its scope, the book is essential reading for undergraduate and graduate students in the neurosciences, as well as postdoctoral fellows and established researchers who are looking for a comprehensive overview of glial-neuronal crosstalk in neuroendocrine systems. This is the eleventh volume in the International Neuroendocrine Federation (INF) Masterclass in Neuroendocrinology series (Volumes 1-7 published by Wiley), which aims to illustrate the highest standards and highlight the latest technologies in basic and clinical research, and aspires to provide inspiration for further exploration into the exciting field of neuroendocrinology. Chapter 6 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Materialart: Online-Ressource
    Seiten: XII, 324 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030623838
    Serie: Masterclass in Neuroendocrinology, 11
    URL: https://doi.org/10.1007/978-3-030-62383-8
    DOI: 10.1007/978-3-030-62383-8
    DDC: 612.8
    Sprache: Englisch
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  • 35
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    Glycobiology of the Nervous System (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Neurosciences. ; Zoology. ; Neurochemistry. ; Neuroscience. ; Zoology. ; Neurochemistry.
    Beschreibung / Inhaltsverzeichnis: 1. Introduction to the complexity of cell surface and tissue matrix glycoconjugates. -- 2. Introduction to cells comprising the nervous system. -- 3. Synthesis -- processing -- and function of N-glycans in N-glycoproteins. -- 4. Synthesis of O-linked glycoconjugates in the nervous system. -- 5. Chemistry and function of glycosaminoglycans in the nervous system. -- 6. Use of glycan-targeted antibodies/lectins to study the expression/function of glycosyltransferases in the nervous system. -- 7. Capillary electrophoresis and mass spectrometry-based glycosylation analysis in glycomics and glycoproteomics. -- 8. Structural analysis of oligosaccharides and glycoconjugates using NMR. -- 9. Glycolipid and glycoprotein expression during neural development. -- 10. Gangliosides and cell surface ganglioside glycohydrolases in the nervous system (request them to include gal-cer and sulfatide). -- 11. Role of myelin-associated glycoproteins in the peripheral nervous system. -- 12. Glycosignaling: a general review. -- 13. Glycosphingolipids in the regulation of the nervous system. -- 14. O-GlcNAcylation of neuronal proteins: Roles in neuronal functions and in neurodegeneration. -- 15. Glycoconjugates in nuclear membranes. -- 16. N-glycosylation in regulation of the nervous system. -- 17. Role of carbohydrates in the interaction of pathogens with neural cells. -- 18. Glycoconjugate changes in aging and age-related diseases. -- 19. Gangliosides and glycolipids in neurodegenerative disorders. -- 20. Inborn errors of glycosphingolipid catabolism and potential treatment. -- 21. Neurological aspects of human glycosylation disorders. -- 22. Glycoconjugates and neural tumors. -- 23. Galectins and neuroinflammation . -- 24. Glycoconjugates and neuroimmunological diseases. -- 25. Targeting nanoparticle drug carriers to the brain. -- 26. Use of quantum dots to treat inherited lysosomal storage diseases. -- 27. MALDI-FTICR MS imaging of nervous system glycoconjugates.
    Kurzfassung: This new edition provides comprehensive coverage of the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic fundamental principles as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. New topics include a detailed discussion of cells found within the nervous system, an extensive listing of congenital disorders of glycosylation of both proteins and lipids, the roles of glycans in neuronal axon growth/guidance and voltage-gated channels, the role of intra-lysosomal luminal vesicles in lysosomal storage disorders, and, in the time of the COVID-19 pandemic, the role of carbohydrates in infection by SARS-CoV-2. The breadth and depth of topics covered make this an essential reference for those new to the field as well as for more experienced investigators.
    Materialart: Online-Ressource
    Seiten: XII, 501 p. 96 illus., 73 illus. in color. , online resource.
    Ausgabe: 2nd ed. 2023.
    ISBN: 9783031123900
    Serie: Advances in Neurobiology, 29
    URL: https://doi.org/10.1007/978-3-031-12390-0
    DOI: 10.1007/978-3-031-12390-0
    DDC: 612.8
    Sprache: Englisch
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  • 36
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    Neuroscience of Social Stress (2022)
    Cham :Springer International Publishing :
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    Schlagwort(e): Psychobiology. ; Human behavior. ; Behavioral Neuroscience.
    Beschreibung / Inhaltsverzeichnis: Part I Preclinical Research: Neuroendocrine Mechanisms of Social Bonds and Separation Stress in Rodents, Dogs, and Other Species -- Methods and Challenges in Investigating Sex-Specific Consequences of Social Stressors in Adolescence in Rats: Is It the Stress or the Social or the Stage of Development?- Social stress-induced neuroinflammation and mitochondrial dysfunction as a link to depression and cardiovascular disease comorbidity -- Mean Girls: Social Stress Models for Female Rodents -- Development of Mixed Anxiety/ Depression-Like State as a Consequence of Chronic Anxiety: Review of Experimental Data -- Unravelling the Neuroinflammatory Mechanisms Underlying the Effects of Social Defeat Stress on Use of Drugs of Abuse -- Social Stress and Aggression in Murine Models -- More or less: glucocorticoid roles in aggression -- Neurobiological Bases of Urges for Alcohol Consumption After Social Stress -- Epigenetics of Aggression -- Part II Human Research: Early Life Stress and Neurodevelopment in Adolescence: Implications for Risk and Adaptation -- Effects of Parenting Environment on Child and Adolescent Social-Emotional Brain Function -- The Stressed Brain: Neural Underpinnings of Social Stress Processing in Humans -- Social Acts and Anticipation of Social Feedback -- Clinical Outcomes of Severe Forms of Early Social Stress -- Childhood Violence Exposure, Inflammation, and Cardiometabolic Health -- Social Support Effects on Neural Stress and Alcohol Reward Responses -- Neural Underpinnings of Social Stress in Human Addiction.
    Kurzfassung: Social stress has emerged as a research front in the neurosciences, and this volume highlights recent insights in brain mechanisms and methodological advances. The topics range from the evolutionary origins of coping with social challenges to neural mechanism-driven focus on novel treatment targets. The parallel presentation of work with animal models and human subjects is bound to be useful to a broad research community.
    Materialart: Online-Ressource
    Seiten: VIII, 515 p. 100 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031042560
    Serie: Current Topics in Behavioral Neurosciences, 54
    URL: https://doi.org/10.1007/978-3-031-04256-0
    DOI: 10.1007/978-3-031-04256-0
    DDC: 612.8
    Sprache: Englisch
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    Anhedonia: Preclinical, Translational, and Clinical Integration (2022)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Psychiatry. ; Neuroscience. ; Psychiatry.
    Beschreibung / Inhaltsverzeichnis: Section I. Anhedonia – History, Etiology, and Assessments -- 1. Historical Perspective -- 2. Clinical and Behavioral Assessments -- 3. Developmental Trajectories: Preclinical -- 4. Developmental Trajectories: Clinical -- 5. Genetics Contributions -- 6. Environmental Contributions -- Section II. Anhedonia in Psychiatric and Neurological Disorders -- 7. Depression and Bipolar Disorder -- 8. Schizophrenia -- 9. Substance Use Disorder -- 10. Nicotine Dependence -- 11. Posttraumatic Stress Disorder -- 12. Anxiety -- 13. Eating Disorders -- 14. Autism and Developmental Disorders -- 15. Neurodegenerative Disorders -- Section III. Reward Processing Systems in Anhedonia -- Reward Responsiveness -- 16. Pleasure -- 17. Anticipation -- Reward Valuation -- 18. Reward Value – Delay and Reward Magnitude -- 19. Effort/Motivation -- Reward Learning -- 20. Reward Prediction Error -- 21. Probabilistic and Reinforcement Learning -- Section IV. Treatments -- 22. Pharmacological Treatments for Anhedonia -- 23. Psychological Treatments for Anhedonia -- 24. Neurostimulation -- Section V. Special Topics -- 25. Inflammation and Anhedonia -- 26. Computational Modeling of Anhedonia -- 27. Anhedonia and Suicide.
    Kurzfassung: Anhedonia is a key symptom (and often risk factor) for various neuropsychiatric disorders, including depression, schizophrenia, substance use disorders, post-traumatic stress disorders, and Parkinson's Disease, among others. Across disorders, anhedonia has been associated with worse disease course, including poor response to pharmacological, psychological and neurostimulation treatments as well as completed suicide. Mounting evidence emerging from preclinical and translational sciences has clarified that "anhedonia" can be parsed into partially independent subcomponents, including incentive motivation, consummatory pleasure, reward learning, and effort-based decision making, pointing to distinct neurobiological substrates that could underlie anhedonic phenotypes. Taking an integrative approach that emphasizes cross-species integration and dimensional conceptualization of mental illnesses (e.g., Research Domain Criteria (RDoC)), this book represents the most comprehensive evaluation, synthesis and integration of theories and empirical findings focused on anhedonia. Organized across five parts, the handbook starts with chapters on the history, etiology, and assessments of anhedonia (Part I), followed by a section on the role of anhedonia in psychiatric and neurological disorders (Part II). Using the RDoC Matrix as a guide, Part III presents chapters synthetizing preclinical and clinical findings on different reward processing subdomains (e.g., reward responsiveness, reward valuation, reward learning). Part IV is focused on selected special topics, including historical and current perspectives on the transdiagnostic nature and importance of social anhedonia, the role of inflammation in the pathophysiology of anhedonia, the use of computational modeling to “dissect” anhedonia and improve its understanding, and links between anhedonia and suicide. Finally, Part V includes chapters on pharmacological, psychological and neurostimulation treatments for anhedonia.
    Materialart: Online-Ressource
    Seiten: XI, 535 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031096839
    Serie: Current Topics in Behavioral Neurosciences, 58
    URL: https://doi.org/10.1007/978-3-031-09683-9
    DOI: 10.1007/978-3-031-09683-9
    DDC: 612.8
    Sprache: Englisch
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    Dendritic Spines : Structure, Function, and Plasticity (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Neurophysiology. ; Developmental neurobiology. ; Neuroscience. ; Neurophysiology. ; Development of the Nervous System.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Introduction: What are dendritic spines? -- Chapter 2: Techniques to render dendritic spines visible in the microscope -- Chapter 3: Electrophysiology of dendritic spines: information processing, dynamic compartmentalization and synaptic plasticity -- Chapter 4: Dendritic spines, synaptogenesis and synaptic pruning for the developmental organization of brain circuits -- Chapter 5: Neurotrophic factors and dendritic spines -- Chapter 6: Glial cell modulation of dendritic spine structure and synaptic function -- Chapter 7: Dendritic spines in learning and memory: from first discoveries to current insights -- Chapter 8: Steroid hormone interaction with dendritic spines: implications for neuropsychiatric disease -- Chapter 9: Morphological features of human dendritic spines.
    Kurzfassung: This reference provides detailed coverage of dendritic spines, the fascinating neuronal components that modulate synaptic transmission, development, strength, and plasticity and are involved in the function of multiple areas of the nervous system. The density, shape, and function of spines may indicate the cellular connectivity and synaptic plasticity in normal and pathological conditions. This field has undergone dramatic advances in terms of techniques and experimental findings from in vitro to in vivo data, from animal models to human neurons, and computational models using artificial intelligence. To address these cutting-edge findings, the book provides state-of-the-art, comprehensive coverage with chapters written by the leading international researchers in the field. The authors consider the multiple implications for the study of dendritic spines with broad implications in the neurosciences and related areas.
    Materialart: Online-Ressource
    Seiten: XV, 499 p. 123 illus., 103 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031361593
    Serie: Advances in Neurobiology, 34
    URL: https://doi.org/10.1007/978-3-031-36159-3
    DOI: 10.1007/978-3-031-36159-3
    DDC: 612.8
    Sprache: Englisch
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  • 39
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    Fear Extinction : From Basic Neuroscience to Clinical Implications (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Neuropsychology. ; Clinical psychology. ; Psychiatry. ; Neuroscience. ; Neuropsychology. ; Clinical Psychology. ; Psychiatry.
    Beschreibung / Inhaltsverzeichnis: Preface -- PART 1: To fear or not -- Disambiguating fear as an emotional state vs. threat detection. Molecular and Neural circuits of fear extinction. Psychological and theoretical elements on the concept of fear extinction. Neural circuit of fear extinction: psychophysiology -- PART 2: Individual differences in fear extinction -- The impact of sex differences and sex hormones on fear extinction. Impact of sleep on fear extinction. Impact of stress and exercise on fear extinction. Intersect between the intrinsic and extrinsic factors that modulate fear extinction -- PART 3: Psychopathology -- Fear extinction and its relevance to psychopathology. Developmental fear and its extinction imaging. Fear extinction and adult psychopathology -- Part 4: Therapeutics and neuromodulations of fear extinction -- Exposure therapy and other behavioral therapeutics targeting fear extinction circuits. Novel pharmacotherapeutics targeting fear extinction circuits. Reconsolidation and its link and impact on fear extinction. Technological advances in exposure therapy: virtual and augmented reality. Novel approaches using neurostimulation targeting fear extinction.
    Kurzfassung: This book aims to provide the reader a neuroscientific understanding surrounding a very simple question: how do we learn not to fear? Exploring answers to this question is very important for two reasons. First, learning about the neural mechanisms of fear extinction is of relevance to everyone’s life - it is such a basic yet relevant question to our daily experiences. Therefore, understanding brain mechanisms of fear and its regulation is essential from a basic neuroscience point of view. Second, excessive fear and the inability to regulate its expression is one of the hallmarks of fear-, anxiety-, trauma-, and stressor-related psychopathologies. And as such, learning about how fear is acquired, stored, expressed, and regulated could help advance our understanding of the etiology of psychopathology, the maintenance of symptoms pertaining to failure to regulate fear, and could help us develop novel therapeutics to equip providers and patients with the tools to better quell their fears. The contributions contained in this book are provided by experts in the fields of basic and clinical neuroscience, experimental and clinical psychology, and neuropsychiatry. The contributions are organized to start the reader with basic definitions of how we define fear, how we study its neural circuits at the molecular and cellular levels, how to study human behavior and the brain using state-of-the art experimental and statistical tools, to how much fear contributes to psychopathology. This volume ends with current advances aimed to enhance the capacity to extinguish fear; a clinical result that would aid in the treatment of multiple psychiatric disorders, followed by a discussion on future directions of this highly important and relevant field.
    Materialart: Online-Ressource
    Seiten: VIII, 387 p. 100 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031430053
    Serie: Current Topics in Behavioral Neurosciences, 64
    URL: https://doi.org/10.1007/978-3-031-43005-3
    DOI: 10.1007/978-3-031-43005-3
    DDC: 612.8
    Sprache: Englisch
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    The Complexity of Bird Behaviour : A Facet Theory Approach (2020)
    Cham :Springer International Publishing :
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    Schlagwort(e): Psychobiology. ; Human behavior. ; Animal migration. ; Biology Technique. ; Physiology. ; Behavioral Neuroscience. ; Animal Migration. ; Experimental Organisms. ; Animal Physiology.
    Beschreibung / Inhaltsverzeichnis: Preface -- Chapter 1. Studying Birds -- Chapter 2. Mapping Sentences and Facet Theory -- Chapter 3. How to Develop a Mapping Sentence: The Example of Avian Sleep -- Chapter 4. Complex Avian Behaviour and Cognition: A Mapping Sentence Approach -- Chapter 5 -- Studying Avian Cognition in the Wild: Avian Psychometrics -- Chapter 6. Interpreting Avian Play, Murmuration of Starlings and Oology (Classifying Birds' Eggs) -- Chapter 7. Conclusion -- Glossary -- Index.
    Kurzfassung: This book presents the facet theoretical framework as a tool for facilitating the conception of complex animal behaviour research and the design of research procedures through employing mapping sentences. Using the facet theoretical framework, this book takes a holistic view of bird behaviour. Components of bird behavior are identified and then reassembled to facilitate an understanding of the behaviour in the context of its natural occurrence. This provides new insight on both the parts of the behaviour and how these interact as a whole. The multi-faceted approach to designing, evaluating and understanding bird behavior presented offers a template that is adaptable for investigating a wide variety of avian species and different forms of behaviour. Behavioural biologists, animal and comparative psychologists, other natural and behavioural scientists, as well as students of these disciplines will find this book to be an interesting and enlightening read.
    Materialart: Online-Ressource
    Seiten: XXXVII, 203 p. 29 illus., 6 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030121921
    URL: https://doi.org/10.1007/978-3-030-12192-1
    DOI: 10.1007/978-3-030-12192-1
    DDC: 612.8
    Sprache: Englisch
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  • 41
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    COVID-19 and Sleep: A Global Outlook (2023)
    Singapore :Springer Nature Singapore :
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    Schlagwort(e): Neurosciences. ; Public health. ; Medicine Research. ; Biology Research. ; Neuroscience. ; Public Health. ; Biomedical Research.
    Beschreibung / Inhaltsverzeichnis: 1. The effect of sleep disruption and circadian misalignment on the immune system -- 2. Changes in the sleep and circadian pattern of sleep during the COVID-19 pandemic -- 3. Anxiety and depression during the COVID-19 pandemic and their impact on sleep -- 4. Sleep problems during the COVID-19 pandemic in children and adolescents -- 5.Sleep problems during the COVID-19 pandemic in children and adolescents -- 6. Sleep disturbances among healthcare workers during the COVID-19 pandemic -- 7. Sleep disturbances among patients with COVID-19 infection -- 8. Sleep patterns and sleep disturbances during the lockdown periods -- 9. Impact of COVID-19 Mobility Restrictions on Sleep and Wellbeing -- 10. COVID-19 vaccines and sleep disturbances -- 11. Sleep during the COVID-19 pandemic: structural inequity and racial disparity -- 12. The effect of cognitive-behavioral therapy and coping strategies on sleep disturbances during the COVID-19 pandemic -- 13. Sleep and circadian rhythm in post-COVID-19 patients -- 14. COVID-19 and obstructive sleep apnea -- 15. The correlation between COVID-19 infection and restless legs syndrome -- 16. Impact of COVID-19 pandemic lockdown on disorders of hypersomnolence -- 17. Sleep, Physical Activity, and Diet Patterns During COVID-19 Pandemic -- 18. Impact of screen time during the pandemic of COVID-19 on sleep habits -- 19. Dreams and nightmares during the COVID-19 pandemic -- 20. The impact of the COVID-19 pandemic on sleep medicine services -- 21. Protocols for conducting sleep studies during pandemics -- 22. Management of hospital and home positive airway pressure machines during pandemics -- 23. Telemedicine and telemonitoring of sleep disorders during the COVID-19 pandemic -- 24.Changes in Positive Airway Pressure Application and Practices in Patients with Sleep-Related Breathing Disorder during the COVID-19 Pandemic -- 25. Potential Therapeutic Effects of Melatonin on SARS-CoV-2 Infection.
    Kurzfassung: This book examines the correlation of the coronavirus disease-19 [CE1] [AAS2] (COVID-19) infection with sleep, circadian rhythm, and sleep disorders. The chapters of the book explore sleep problems during the COVID-19 pandemic and its association with psychological distress and also review the prevalence of clinical cases of insomnia, anxiety, and depression in COVID-19 patients. The book further presents the correlation between sleep, circadian rhythms, and immunity that contributes toward more severe COVID-19. It summarizes the evidence on the interplay between circadian biology, sleep, and COVID-19. The chapters of the book discuss the relationship between obstructive sleep apnea (OSA) and adverse COVID-19 outcomes. Towards the end, the book presents studies on the anti-inflammatory, antioxidant, and immunotropic properties of melatonin and provides mechanistic insights into the potential therapeutic use of melatonin during the SARS-CoV-2 infection. The last chapter describes the publication output of sleep-related research during the pandemic and provides an overview and trends on sleep and covid-19 publication output. This book is an excellent source for neurologists, sleep specialists, and public health specialists.
    Materialart: Online-Ressource
    Seiten: XXVI, 430 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789819902408
    Serie: Progress in Sleep Research,
    URL: https://doi.org/10.1007/978-981-99-0240-8
    DOI: 10.1007/978-981-99-0240-8
    DDC: 612.8
    Sprache: Englisch
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    Hair Cell Regeneration (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Otorhinolaryngology. ; Neuroscience. ; Otorhinolaryngology.
    Beschreibung / Inhaltsverzeichnis: Sensory Regeneration in the Inner Ear: History, Strategies and Prospects -- Non-mammalian Hair Cell Regeneration: Cellular Mechanisms of Morphological and Functional Recovery -- Cell Junctions and the Mechanics of Hair Cell Regeneration -- Mammalian Hair Cell Regeneration -- Specification and Plasticity of Mammalian Cochlear Hair Cell Progenitors -- Inner Ear Cells from Stem Cells – a Path Towards Inner Ear Cell Regeneration -- Spiral ganglion neuron regeneration in the cochlea: regeneration of synapses, axons and cells -- Genetic and Epigenetic Strategies for Promoting Hair Cell Regeneration in the Mature Mammalian Inner Ear.
    Kurzfassung: This volume provides a detailed update on progress in the field of hair cell regeneration with emphasis on more "prospective" views of the various facets of regeneration research. Sensory Regeneration in the Inner Ear: History, Strategies and Prospects Mark E. Warchol, and Jennifer S. Stone Non-mammalian Hair Cell Regeneration: Cellular Mechanisms of Morphological and Functional Recovery Madeleine Hewitt, David W. Raible, and Jennifer S. Stone Cell Junctions and the Mechanics of Hair Cell Regeneration Mark A. Rudolf, and Jeffrey T. Corwin Mammalian Hair Cell Regeneration Ruth Taylor, and Andrew Forge Specification and Plasticity of Mammalian Cochlear Hair Cell Progenitors Melissa M. McGovern, and Andrew K. Groves Inner Ear Cells from Stem Cells – a Path Towards Inner Ear Cell Regeneration Amanda Janesick, Eri Hashino, and Stefan Heller Spiral ganglion neuron regeneration in the cochlea: regeneration of synapses, axons and cells Steven H. Green, Sepand Bafti, Benjamin M. Gansemer, A. Eliot Shearer, Muhammad Taifur Rahman, Mark E. Warchol, and Marlan R. Hansen Genetic and Epigenetic Strategies for Promoting Hair Cell Regeneration in the Mature Mammalian Inner Ear Brandon C. Cox, John V. Brigande, and Bradley J. WaltersDr. Mark Warchol is Professor of Otolaryngology at Washington University School of Medicine in St. Louis. Dr. Jennifer Stone is Research Professor of Otolgaryngolldy/Head and Neck Surgery, University of Washington School of Medicine, Seattle. Dr. Allison Coffin is an Associate Professor in the Department of Integrative Physiology and Neuroscience at Washington State University Vancouver. Dr. Arthur N. Popper is Professor Emeritus and research professor in the Department of Biology at the University of Maryland, College Park. Dr. Richard R. Fay (Deceased) was Distinguished Research Professor of Psychology at Loyola University Chicago.
    Materialart: Online-Ressource
    Seiten: XVI, 229 p. 44 illus., 35 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031206610
    Serie: Springer Handbook of Auditory Research, 75
    URL: https://doi.org/10.1007/978-3-031-20661-0
    DOI: 10.1007/978-3-031-20661-0
    DDC: 612.8
    Sprache: Englisch
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  • 43
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    IschemiRs: MicroRNAs in Ischemic Stroke : From Basics to Clinics (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Neurosciences. ; Medical genetics. ; Immunology. ; Cell death. ; Cytology. ; Stress (Physiology). ; Neuroscience. ; Medical Genetics. ; Immunology. ; Cell Death. ; Cellular Stress.
    Beschreibung / Inhaltsverzeichnis: Preface -- Chapter 1: microRNAs in normal brain physiology -- Chapter 2: Ischemic stroke: An imperative need for effective therapy -- Chapter 3: MicroRNAs in ischemic stroke pathophysiology: Special emphasis on early molecular events -- Chapter 4: microRNA regulation of ischemic stroke inflammatory and immune response -- Chapter 5: Regulatory role of microRNAs in ischemic cell death -- Chapter 6: The emerging role of microRNAs in post-ischemic angiogenesis and neurogenesis -- Chapter 7: MicroRNAs as potential diagnostic, prognostic and therapeutic biomarkers in ischemic stroke -- Chapter 8: Interplay between microRNAs and other cerebrovascular diseases -- Chapter 9: New insights into the regulatory role of lncRNA, circRNA, piRNAs, and ceRNAs in ischemic stroke -- Chapter 10: Computational resources for microRNA research -- Chapter 11: MicroRNA-targeted therapeutics for ischemic stroke: Status, gaps and the way forward.
    Kurzfassung: There has been an enormous increase in information relating to microRNA (miRNA) and its strategic role in numerous diseases. This book reviews the emerging role of microRNAs in cerebral ischemia, providing comprehensive details of the links between this small RNA molecule and ischemic stroke, the more prevalent of the two main types of stroke. The chapters address questions relating to microRNA’s function in various pathological features of stroke, like oxidative stress, excitotoxicity and cell death, as well as its role as a biomarker and diagnostic agent, and the current therapeutic interventions. Further, the book highlights the latest research on how miRNAs contribute to neuroregeneration following stroke, discussing the myriad computational tools and databases used in miRNA research, and decsribes how how miRNA modulates other cerebrovascular diseases. The book concludes with fresh insights into the effect of long non-coding RNA in cerebral ischemia.
    Materialart: Online-Ressource
    Seiten: XVI, 138 p. 7 illus., 6 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811547980
    URL: https://doi.org/10.1007/978-981-15-4798-0
    DOI: 10.1007/978-981-15-4798-0
    DDC: 612.8
    Sprache: Englisch
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  • 44
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    Online-Ressource
    New Therapies to Prevent or Cure Auditory Disorders (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Neurosciences. ; Otorhinolaryngology. ; Neuroscience. ; Otorhinolaryngology.
    Kurzfassung: This volume focuses on new molecular therapies that aim to prevent specific pathologies of the ear, like age-related hearing loss, noise-induced hearing loss and ototoxicity. The book discusses the regenerative capacity of hair cells in the inner ear, exploring the idea that hair cells’ capacity to regenerate appears “repressed” in adult mammals, but that it will be possible to re-activate regeneration with an appropriate therapeutic approach. The book provides an overview of inflammatory and immune cells in the cochlear lateral wall, the pathways involved in cochlear damage, and their potential as therapeutic targets. It also describes the significant advances in animal models which play an important role in revealing the underlying mechanisms and treatment for tinnitus and hyperacusis. Finally, the book describes two new automatic and robust measures to evaluate hearing loss and tinnitus in preclinical models.
    Materialart: Online-Ressource
    Seiten: VII, 186 p. 29 illus., 25 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030404130
    URL: https://doi.org/10.1007/978-3-030-40413-0
    DOI: 10.1007/978-3-030-40413-0
    DDC: 612.8
    Sprache: Englisch
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  • 45
    Online-Ressource
    Online-Ressource
    Neuroscience and the Problem of Dual Use : Neuroethics in the New Brain Research Projects (2020)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Bioethics. ; Security, International. ; Security systems. ; Neuroscience. ; Bioethics. ; International Security Studies. ; Security Science and Technology.
    Beschreibung / Inhaltsverzeichnis: 1. Modern Neuroscience -- 2. The Chemical and Biological Non-Proliferation Regime in 2018 -- 3. Neuroethics and the Regulation of Misuse -- 4. Dual-Use Neuroscience? -- 5. The EU Human Brain Project -- 6. The US BRAIN Initiative -- 7. Global Neuroethics in Early 2019 -- 8. Japan’s BRAIN/Minds Project -- 9. China’s Brain Project -- 10. Conclusion.
    Kurzfassung: After COVID-19 ensuring biological security will be a critical necessity. Neuroscience and the Problem of Dual Use focuses on the fact that benignly intended research in the life sciences could be misused for hostile purposes. It details the revolution that is taking place in neuroscience during this period of instability in international security, describes the new major State-funded brain research projects, and suggests ways in which hostile misuse could be prevented in coming decades.
    Materialart: Online-Ressource
    Seiten: XXV, 210 p. 4 illus., 3 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030537906
    Serie: Advanced Sciences and Technologies for Security Applications,
    URL: https://doi.org/10.1007/978-3-030-53790-6
    DOI: 10.1007/978-3-030-53790-6
    DDC: 612.8
    Sprache: Englisch
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  • 46
    Online-Ressource
    Online-Ressource
    Make Life Visible (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Neurosciences. ; Immunology. ; Cytology. ; Neuroscience. ; Immunology. ; Cell Biology.
    Beschreibung / Inhaltsverzeichnis: Part 1: Visualizing and Controlling Molecules for Life -- Chapter 1. Photoacoustic Tomography: Deep Tissue Imaging by Ultrasonically Beating Optical Diffusion -- Chapter 2. Regulatory Mechanism of Neural Stem Cells Revealed by Optical Manipulation of Gene Expressions -- Chapter 3. Eavesdropping on Biological Processes with Multi-Dimensional Molecular Imaging -- Chapter 4. Apical microtubules define the function of epithelial cell sheets consisting of non-ciliated or multi-ciliated cells -- Chapter 5. Illuminating the brain -- Chapter 6. Optogenetic assemblies of cortical force-generating complexes during mitosis -- Chapter 7. In vivo Imaging Probes with Tunable Chemical Switches -- Chapter 8. Circuit-dependent striatal PKA and ERK signaling underlying action selection -- Chapter 9. Electrophysiology, Unplugged: New Chemical Tools to Image Voltage -- Chapter 10. Molecular dynamics revealed by single-molecule FRET measurement -- Chapter 11. Comprehensive approaches using luminescence to studies of cellular functions -- Part II: Imaging Disease Mechanisms -- Chapter 12. Make Chronic Pain Visible -- Chapter 13. Cortical plasticity after spinal cord injury using resting-state functional magnetic resonance imaging -- Chapter 14. Multimodal Label-free imaging to assess compositional and morphological changes in cells during immune activation -- Chapter 15. Investigating in vivo myocardial and coronary molecular pathophysiology in mice with X-ray radiation imaging approaches -- Chapter 16. Visualizing the Immune Response to Infections -- Chapter 17. Imaging Sleep and Wakefulness -- Chapter 18. Abnormal local translation in dendrites impairs cognitive functions in neuropsychiatric disorders -- Chapter 19. Imaging synapse formation and remodeling in vitro and in vivo -- Part III: Imaging-based Diagnosis and Therapy -- Chapter 20. How MRI makes the Brain Visible -- Chapter 21. Intravital multiphoton imaging revealing cellular dynamics in vivo -- Chapter 22. Theranostic Near Infrared Photoimmunotherapy for Cancer -- Chapter 23. Novel and integrated imaging on Chronic Fatigue -- Chapter 24. Novel fluorescent probes for rapid tumor imaging and fast glutathione dynamics -- Chapter 25. Coronary Heart Disease Diagnosis: Engineering Triumphs, Economic Barriers -- Chapter 26. Live imaging of the skin immune responses -- Chapter 27. Development of a horizontal CT and its application to musculoskeletal disease -- Chapter 28. The Future of Precision Health & Integrated Diagnostics -- Chapter 29. Imaging and therapy against hypoxic tumors with 64Cu-ATSM.
    Kurzfassung: This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completely impossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology in the broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into three parts, the first of which addresses the topic of visualizing and controlling molecules for life. Th e second part is devoted to imaging of disease mechanisms, while the final part comprises studies on the application of imaging technologies to diagnosis and therapy. Th e book contains the proceedings of the 12th Uehara International Symposium 2017, “Make Life Visible” sponsored by the Uehara Memorial Foundation and held from June 12 to 14, 2017. It is written by leading scientists in the field and is an open access publication under a CC BY 4.0 license. .
    Materialart: Online-Ressource
    Seiten: IX, 292 p. 137 illus., 106 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811379086
    URL: https://doi.org/10.1007/978-981-13-7908-6
    DOI: 10.1007/978-981-13-7908-6
    DDC: 612.8
    Sprache: Englisch
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  • 47
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    Functional Brain-Heart Interplay : From Physiology to Advanced Methodology of Signal Processing and Modeling (2021)
    Cham :Springer International Publishing :
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    Schlagwort(e): Computational neuroscience. ; Biomedical engineering. ; Neurology . ; Neurophysiology. ; Neuroanatomy. ; Image processing. ; Computational Neuroscience. ; Biomedical Engineering and Bioengineering. ; Neurology. ; Neurophysiology. ; Nervous System. ; Image Processing.
    Beschreibung / Inhaltsverzeichnis: 1. Physiology of Brain-Heart Interplay -- 2. Brain and Heart Signal Processing Methodology -- 3. Quantification of Functional Brain-Heart Interplay -- 4. Exemplary Applications to Real Brain and Heartbeat Data -- 5. Future Direction of Research and Prospective Applications using Functional Brain-Heart Interplay Assessment.
    Kurzfassung: This monograph offers a cross-system exchange and cross-modality investigation into brain-heart interplay. Brain-Heart Interplay (BHI) is a highly interdisciplinary scientific topic, which spreads from the physiology of the Central/Autonomous Nervous Systems, especially Central Autonomic Network, to advanced signal processing and modeling for its activity quantification. Motivated by clinical evidence and supported by recent findings in neurophysiology, this monograph first explores the definition of basic Brain-Heart Interplay quantifiers, and then moves onto advanced methods for the assessment of health and disease states. Non-invasive use of brain monitoring techniques, including electroencephalogram and function Magnetic Resonance Imaging, will be described together with heartbeat dynamics monitoring through pulseoximeter and ECG signals. The audience of this book comprises especially of biomedical engineers and medical doctors with expertise in statistics and/or signal processing. Researchers in the fields of cardiology, neurology, psychiatry, and neuroscience in general may be interested as well.
    Materialart: Online-Ressource
    Seiten: X, 236 p. 109 illus. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030799342
    URL: https://doi.org/10.1007/978-3-030-79934-2
    DOI: 10.1007/978-3-030-79934-2
    DDC: 612.8
    Sprache: Englisch
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  • 48
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    Online-Ressource
    Neurogenetics : Current Topics in Cellular and Developmental Neurobiology (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Zoology. ; Life sciences. ; Behavior genetics. ; Neuroscience. ; Zoology. ; Life Sciences. ; Behavioral Genetics.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction to neurogenetics -- Chapter 2. Neurogenetic analysis in Caenorhabditis elegans -- Chapter 3. Regionalisation of the early nervous system -- Chapter 4. Early neurogenesis and gliogenesis in Drosophila -- Chapter 5. Neural stem cells and brain tumour models in Drosophila -- Chapter 6. Eye development in Drosophila: from photoreceptor specification to terminal differentiation -- Chapter 7. Neurogenetics of memory, learning and forgetting -- Chapter 8. Evolution and origins of nervous systems -- Chapter 9. Neural stem and progenitor cells in the mammalian brain -- Chapter 10. Models of neurodegenerative diseases.
    Kurzfassung: This textbook provides students with knowledge of neurogenetics, neurogenesis, neuronal specification and function, neuronal networks, learning and memory formation, brain evolution, and neurodegenerative diseases. Students are introduced to topics of classical developmental genetics as well as modern molecular and neurogenetic methods. Using a wealth of examples from current research, the textbook takes a strong applied approach. Using animal models such as Drosophila melanogaster and Caenorhabditis elegans as well as mammalian systems, the interrelationships between genes, neurons, nervous systems, and behaviour under normal and pathological conditions are illustrated. The textbook aims encourage students to address biological questions in neurogenetics and to think about the design of their own experiments. It targets primarily master and graduate students in neurobiology, but is also a valuable teaching tool for instructors in these fields.
    Materialart: Online-Ressource
    Seiten: VII, 212 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031077937
    Serie: Learning Materials in Biosciences,
    URL: https://doi.org/10.1007/978-3-031-07793-7
    DOI: 10.1007/978-3-031-07793-7
    DDC: 612.8
    Sprache: Englisch
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  • 49
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    Online-Ressource
    Brain and Lung Crosstalk (2020)
    Singapore :Springer Nature Singapore :
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    Schlagwort(e): Neurosciences. ; Human physiology. ; Neurology . ; Neuroscience. ; Human Physiology. ; Neurology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Neurophysiology and Respiratory system -- Chapter 2. Normal physiology of Respiratory System -- Chapter 3. Brain – Lung crosstalk.
    Kurzfassung: The central nervous system, which includes the brain and spinal cord, has a high metabolic demand. The physiology of the brain is such that it is easily affected by alterations in other systems, which in turn can compromise cerebral blood flow and oxygenation. Together the brain and spinal cord control the automatic function of our body systems. While other systems of body controls individual functions, central nervous system at the same time does many different functions, especially, controlling the function of other systems. This interaction between the brain and other systems is important when it comes to understanding how injuries to the brain can, at times, produce complications in remote organs or systems of the body, such as the lungs. This book explains the lesser-known crosstalks between acutely or chronically affected brain and lung, describing the pathophysiology of the lung following brain injury and discussing in detail the conflicts between the brain and lungs in relation to the tidal volumes, positive end-expiratory pressures, arterial carbon dioxide and oxygen levels, recruitment maneuvers and positioning, as well as potential therapeutic targets. .
    Materialart: Online-Ressource
    Seiten: XIII, 103 p. 27 illus., 26 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811523458
    Serie: Physiology in Clinical Neurosciences – Brain and Spinal Cord Crosstalks,
    URL: https://doi.org/10.1007/978-981-15-2345-8
    DOI: 10.1007/978-981-15-2345-8
    DDC: 612.8
    Sprache: Englisch
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  • 50
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    Neurodevelopmental Disorders : Employing iPSC Technologies to Define and Treat Childhood Brain Diseases (2020)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Neuroscience.
    Beschreibung / Inhaltsverzeichnis: 1. Modeling neurodevelopmental deficits in Tuberous Sclerosis Complex with stem cell-derived neural precursors and neurons -- 2. Advances in human stem cells and genome editing to understand and develop treatment for Fragile X syndrome -- 3. IPSC MODELS OF CHROMOSOME 15Q IMPRINTING DISORDERS: FROM DISEASE MODELING TO THERAPEUTIC STRATEGIES -- 4. Creating iPSC based models to understand the signaling and cellular phenotypes in idiopathic autism and 16p11.2 derived neurons -- 5. Dysregulation of Neurite Outgrowth and Cell Migration in Autism and other Neurodevelopmental Disorders -- 6. Investigation of Schizophrenia with Human Induced Pluripotent Stem Cells -- 7. Modeling Inflammation on Neurodevelopmental disorders using pluripotent stem cells -- 8. Astrocyte-derived exosomes in an iPSC model of bipolar disorder -- 9. Two- and there-dimensional stem cell models to define mechanisms underlying psychiatric disorders -- 10. Development of a 3-D organoid system using human induced pluripotent stem cells to model idiopathic autism.
    Kurzfassung: This book contains a compendium of induced pluripotent stem cells (iPSCs) articles and reviews concerning state of the art technologies and how they are being applied to human neurodevelopmental disorders. With the establishment of effective technologies to produce iPSCs and their derivatives, like neural precursors, neurons, and glia, researchers have new platforms to study neurodevelopmental disorders. iPSC technology enables researchers to study how human neurons develop in individuals with neurodevelopmental disorders, providing an unparalleled opportunity to investigate their etiology. In turn, researchers have now begun to understand the underlying molecular and cellular pathways that contribute to human diseases. iPSCs technologies also provide an emerging tool for future translational studies and disease classification. The chapters will emphasize how among the diverse idiopathic and genetic disorders, there are common clinical as well as cellular and molecular phenotypes.
    Materialart: Online-Ressource
    Seiten: IX, 305 p. 26 illus., 23 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030454937
    Serie: Advances in Neurobiology, 25
    URL: https://doi.org/10.1007/978-3-030-45493-7
    DOI: 10.1007/978-3-030-45493-7
    DDC: 612.8
    Sprache: Englisch
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  • 51
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    Nutrigenomics and the Brain (2022)
    Singapore :Springer Nature Singapore :
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    Schlagwort(e): Neurosciences. ; Nutrition   . ; Quantitative research. ; Nervous system Diseases. ; Neuroimmunology. ; Neuroscience. ; Nutrition. ; Data Analysis and Big Data. ; Neurological Disorders. ; Neuroimmunology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Nutrigenomics; a broader concept -- Chapter 2. Gene-environment interaction -- Chapter 3. Gene-gut-brain - axis (gene–based personalized medicine) -- Chapter 4. Nutrigenomics of aging -- Chapter 5. Nutrigenomics and Mental health -- Chapter 6. Nutrigenomics and neurodevelopmental disorders -- Chapter 7. Nutrigenomics and Alzheimer’s disease -- Chapter 8. Nutrigenomics and Parkinson’s Disease -- Chapter 9. Nutrigenomics, nutrigenetics and big data -- Chapter 10. Nutrigenomics and Development -- Chapter 11. Early Child malnutrition and neurodevelopment -- Chapter 12. The emerging role of vit D deficiency and Parkinson’s Disease risk -- Chapter 13. Nutrigenomics and autophagy crosstalk -- Chapter 14. Nanoparticles in food additives and brain health.
    Kurzfassung: This book highlights the effect of complex interactions between numerous genetic and environmental factors, including food intake, physical activity, age, and stress on brain physiology and function. It further discusses the mechanistic connection between nutrition and aging towards understanding the effect of the brain on longevity. The book also reviews the efficiency of nutraceutical compounds for treating and preventing of neurodevelopmental and neurodegenerative disorders. It also discusses the role of gut microbiota on the gut-brain axis and presents the role of nutrition in neurological inflammatory diseases.
    Materialart: Online-Ressource
    Seiten: VII, 234 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811692055
    Serie: Nutritional Neurosciences,
    URL: https://doi.org/10.1007/978-981-16-9205-5
    DOI: 10.1007/978-981-16-9205-5
    DDC: 612.8
    Sprache: Englisch
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  • 52
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    Neuroendocrine-Immune System Interactions (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Endocrine glands. ; Immunology. ; Neuroscience. ; Endocrine System. ; Immunology.
    Beschreibung / Inhaltsverzeichnis: Part I. Concepts -- Chapter 1. A History of Immune and Neuroendocrine System Interactions -- Chapter 2. Philosophical Perspectives on Neuroendocrine-Immune Interactions: The Building Block Model and Complementary Neuro-Endocrine-Immune-Microbiota Systems Approaches -- Chapter 3. The Behavioural Immune System of Lower Vertebrates -- Part II. Regulatory Pathways -- Chapter 4. Cytokines and Hypothalamo-Pituitary-Adrenal Axis Activation: Now a Classic of Immune-Neuroendocrine System Interactions -- Chapter 5. Catecholamines and Immunomodulation -- Chapter 6. Neuroendocrine-immune Interactions in Major Depressive Disorder: Glucocorticoids and Glucocorticoid Receptors -- Chapter 7. Brain Fluids, Blood-Brain Interfaces, and Their Involvement in Neuroimmune Regulation During Development and in Adulthood -- Chapter 8. Neuropeptide Binding Autoantibodies Regulating Neuroendocrine Communications -- Part III. Modulation -- Chapter 9. Postnatal Development of Neuroimmune Responses -- Chapter 10. Sex Differences in Neuroendocrine-Immune Interactions -- Chapter 11. Biological Clocks and Immune Function -- Chapter 12. Influence of the Gut Microbiota on Neuroendocrine-Immune Interactions -- Part IV. Disease -- Chapter 13. Energy Balance and Neuroendocrine-Immune Regulation in Chronic Inflammatory and Neoplastic Diseases: An Evolutionary Perspective -- Chapter 14. Autonomic, Immune, Metabolic and Neuroendocrine Dimensions of Anorexia Nervosa: An Integrative View.
    Kurzfassung: The concepts of the neuroendocrine system and the immune system emerged more or less simultaneously in the second half of the 20th century. Although these systems have a high degree of autonomy, it has also become clear that they interact in many ways and at different levels. This book focuses on the neuroendocrine and immune interactions that are fundamental to normal development and maintenance of health. The first introductory chapters are devoted to the historical and philosophical concepts within the field, as well as evolutionary considerations, offering critical interdisciplinary perspectives on the development of this field of research. Without attempting an exhaustive overview, the book then introduces some of the regulatory pathways that mediate interactions between the neuroendocrine and immune systems and examines modulating factors such as age and sex. In addition, several chapters address the importance of neuroendocrine-immune interactions in some disease states. Readers can expect to gain a broad perspective of neuroendocrine-immune interactions in development, health, and disease, along with a critical evaluation of current methods used in the field. Given its scope, the book is essential reading for undergraduate and graduate students with an interest in neuroendocrinology, neuroimmunology, and neuroscience, as well as postdoctoral fellows and established researchers seeking a comprehensive overview and historical perspective of the field of neuroendocrine-immune interactions.
    Materialart: Online-Ressource
    Seiten: XIII, 386 p. 29 illus., 26 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031213588
    Serie: Masterclass in Neuroendocrinology, 13
    URL: https://doi.org/10.1007/978-3-031-21358-8
    DOI: 10.1007/978-3-031-21358-8
    DDC: 612.8
    Sprache: Englisch
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    Neuro-Behçet’s Disease : Pathogenesis, Clinical Aspects, Treatment (2021)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Neuroscience.
    Beschreibung / Inhaltsverzeichnis: 1. Neuro-Behçet’s Disease: Epidemiology and Genetics -- 2. Immunology of Neuro-Behçet’s Disease -- 3. Autoantibodies in Neuro-Behçet Disease -- 4. Animal Models of Behçet’s Disease -- 5. Pathology of Neuro-Behçets Disease -- 6. Behçet’s Disease: Clinical Features -- 7. Neuro-Behçet Syndrome: Differential Diagnosis -- 8. Neuro-Behçet Syndrome: Clinical Features -- 9. The Cerebrospinal Fluid Presentations of Neuro-Behçet Disease -- 10. Imaging of Neuro-Behçet’s Disease -- 11. Neuropsychiatric Symptoms In Neuro-Behçet’s Disease -- 12. Treatment of Neuro-Behçet’s Disease -- 13. Prognosis of Behçet’s Syndrome.
    Kurzfassung: This contributed volume provides a complete overview of Neuro-Behçet’s disease (NBD), one of the most serious manifestations of Behçet’s disease. It serves as a comprehensive and critical review of the current scientific literature regarding NBD, covering the epidemiology, pathology, prognosis, and treatment of the disease. This book is an essential resource for both researchers and physicians working on neurology, rheumatology, and internal medicine fields.
    Materialart: Online-Ressource
    Seiten: VIII, 172 p. 26 illus., 15 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030552732
    URL: https://doi.org/10.1007/978-3-030-55273-2
    DOI: 10.1007/978-3-030-55273-2
    DDC: 612.8
    Sprache: Englisch
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  • 54
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    Optogenetics : Light-Sensing Proteins and Their Applications in Neuroscience and Beyond (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Neurosciences. ; Cytology. ; Biotechnology. ; Neuropsychology. ; Neurology . ; Neuroscience. ; Cell Biology. ; Biotechnology. ; Neuropsychology. ; Neurology.
    Beschreibung / Inhaltsverzeichnis: Part 1. Light-sensitive channels and transporters -- 1. History and Perspectives of Light-Sensing Proteins -- 2. Phototactic behavior of Chlamydomonas -- 3. Structure-Functional Analysis of rhodopsin light sensors -- 4. Molecular Dynamics of Channelrhodopsin -- 5. Photochemistry of Halorhodopsin -- 6. Spectroscopic Dynamics of Microbial Rhodopsins -- 7. Molecular Engineering of Retinylidene Proteins -- 8. A new optogenetic tools from deep ocean -- Part 2. Light-sensitive signaling molecules -- 9. Biology of Light-Sensing Proteins in Plants and Microorganisms -- 10. Optogenetic Potentials of Diverse Animal Opsins -- 11. Enzyme rhodopsins -- 12.Optogenetic photoswitches -- 13.Genetic, biochemical and biophysical studies on flavoprotein photoreceptors -- Part 3. Optogenetics in Biological System -- 14. General Description: Future Prospects of Optogenetics -- 15. Optogenetic Manipulation and Probing -- 16. Visualization and Manipulation Signaling Molecules In Vivo -- 17. Optical Manipulation of Gene Expression -- 18. Optical Manipulation of Intracellular Signaling -- 19. Single Molecule Optogenetics -- 20. Bioluminescence Imaging -- 21. Luminescence Optogenetics -- 22. Optogenetic Imaging of Protein Activity in the Synapse Using 2-Photon Fluorescence Lifetime Imaging Microscopy -- 23. Optogenetics in Drosophila -- 24. Optogenetics in Caenorhabditis elegans -- 25. Optogenetics in zebrafish -- 26. Optogenetics Research Using the Mouse as a Model System -- 27. Optogenetics Research Using Rat -- 28. Optogenetics Research Using Primates -- 29. Organelle Optogenetics -- Part 4. Optogenetics in Neuroscience -- 30. Neuroscientific Frontline of Optogenetics -- 31. Elucidation of Neuronal Circuitry Involved in the Regulation of Sleep/Wakefulness Using Optogenetics -- 32. Multiscale neural activity in the behaving brain -- 33. Optogenetic Analysis of Striatal Connections to Determine Functional Connectomes -- 34. Optogenetics for the Behavior Manipulation of Non-human Primates -- 35. Activity Regulation in the Study of Neural Plasticity -- 36. Optogenetic Control of Synaptic Plasticity -- 37. Casting Light on the Role of Glial Cells in Brain Function -- 38. Optogenetic manipulation of Respiratory Rhythm -- 39. Optogenetic mapping of brain circuitry -- 40. In vivo imaging of Arc transcription -- 41. Neural Circuits for the Formation and Retrieval of Episodic Memories -- Part 5. Medical Optogenetics -- 42. Medical Optogenetics, Overview -- 43. Towards Understanding the Neural Mechanism of Behavioral Phenotypes Seen in Psychiatric Disorders -- 44. Gene Therapy Using Channelrhodopsins to Treat Blindness -- 45. Optogenetic Approaches to Restoring Intrinsic Visual Processing Features in Retinal Ganglion Cells -- 46. Application of optogenetics to epilepsy research -- Part 6. Opto-electro-nano Technologies for Optogenetics -- 47. CMOS-Based Neural Interface Device for Optogenetics -- 48. OLED System for Optogenetics -- 49. Micro-imaging probes, Opto-electrodes, and Virtual Reality Systems for Optogenetics -- 50. Upconversion -- 51. Optical probes for in vivo optogenetics.
    Kurzfassung: This book, now in a thoroughly revised second edition, offers a comprehensive review of the rapidly growing field of optogenetics, in which light-sensing proteins are genetically engineered into cells in order to acquire information on cellular physiology in optical form or to enable control of specific network in the brain upon activation by light. Light-sensing proteins of various living organisms are now available to be exogenously expressed in neurons and other target cells both in vivo and in vitro. Cellular functions can thus be manipulated or probed by light. The new edition documents fully the extensive progress since publication of the first edition to provide an up-to-date overview of the physical, chemical, and biological properties of light-sensing proteins and their application in biological systems, particularly in neuroscience but also in medicine and the optical sciences. Underlying principles are explained and detailed information provided on a wide range of optogenetic tools for the observation and control of cellular signaling and physiology, gene targeting technologies, and optical methods for biological applications. In presenting the current status of optogenetics and emerging directions, this milestone publication will be a “must read” for all involved in research in any way related to optogenetics.
    Materialart: Online-Ressource
    Seiten: XII, 663 p. 241 illus., 197 illus. in color. , online resource.
    Ausgabe: 2nd ed. 2021.
    ISBN: 9789811587634
    Serie: Advances in Experimental Medicine and Biology, 1293
    URL: https://doi.org/10.1007/978-981-15-8763-4
    DOI: 10.1007/978-981-15-8763-4
    DDC: 612.8
    Sprache: Englisch
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    Neural Engineering (2020)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Biomedical engineering. ; Neurology . ; Radiology. ; Biophysics. ; Neuroscience. ; Biomedical Engineering and Bioengineering. ; Neurology. ; Radiology. ; Biophysics.
    Beschreibung / Inhaltsverzeichnis: Introduction to Neurophysiology -- Biopotential Measurements and Electrodes -- EEG Signal Processing: Theory and Applications -- Brain-Computer Interfaces -- Intracortical Brain Machine Interfaces -- Deep Brain Stimulation: Emerging Technologies and Applications -- Transcranial Magnetic Stimulation: Principles and Applications -- Transcranial Electrical Stimulation -- Optogenetics: Novel Brain Interface Technology that Originates in Bioprospecting -- Selective Chronic Recording in the Peripheral Nervous System -- Functional Magnetic Resonance Imaging -- Photoacoustic Tomography of Neural Systems -- Electrophysiological Mapping and Source Imaging -- Exploring Functional and Causal Connectivity in the Brain -- Deep Learning Models with Applications to Brain Image Analysis -- Neural Modeling -- Linear Dynamics & Control of Brain Networks -- Deciphering the Neuronal Population Code -- Machine Intelligence Based Epileptic Seizure Forecasting -- Retinal Prosthesis -- Retinal Bioengineering -- Neural Tissue Engineering -- Index.
    Kurzfassung: This third edition overviews the essential contemporary topics of neuroengineering, from basic principles to the state-of-the-art, and is written by leading scholars in the field. The book covers neural bioelectrical measurements and sensors, EEG signal processing, brain-computer interfaces, implantable and transcranial neuromodulation, peripheral neural interfacing, neuroimaging, neural modelling, neural circuits and system identification, retinal bioengineering and prosthetics, and neural tissue engineering. Each chapter is followed by homework questions intended for classroom use. This is an ideal textbook for students at the graduate and advanced undergraduate level as well as academics, biomedical engineers, neuroscientists, neurophysiologists, and industry professionals seeking to learn the latest developments in this emerging field. Advance Praise for Neural Engineering, 3rd Edition: “A comprehensive and timely contribution to the ever growing field of neural engineering. Bin He’s edited volume provides chapters that cover both the fundamentals and state-of-the-art developments by the world’s leading neural engineers." Dr. Paul Sajda, Department of Biomedical Engineering, Electrical Engineering and Radiology, Columbia University “Neural Engineering, edited by Prof. He, is an outstanding book for students entering into this fast evolving field as well as experienced researchers. Its didactic and comprehensive style, with each chapter authored by leading scientific authorities, provides the ultimate reference for the field.” Dr. Dario Farina, Department of Bioengineering, Imperial College London, London, UK "Neural Engineering has come of age. Major advances have made possible prosthesis for the blind, mind control for quadraplegics and direct intervention to control seizures in epilepsy patients. Neural Engineering brings together reviews by leading researchers in this flourishing field. Dr. Terrence Sejnowski, Salk Institute for Biolgical Studies and UC San Diego.
    Materialart: Online-Ressource
    Seiten: XVI, 699 p. 407 illus., 299 illus. in color. , online resource.
    Ausgabe: 3rd ed. 2020.
    ISBN: 9783030433956
    URL: https://doi.org/10.1007/978-3-030-43395-6
    DOI: 10.1007/978-3-030-43395-6
    DDC: 612.8
    Sprache: Englisch
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  • 56
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    GeNeDis 2018 : Geriatrics (2020)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Medical genetics. ; Neuroscience. ; Medical Genetics.
    Beschreibung / Inhaltsverzeichnis: A hypothesis of circulated microRnas implication in high incidence of atrial fibrillation and other electrocardiographic abnormalities in cancer patients -- Central Line-associated Bloodstream Infections (CLABSI) Incidence and the role of obesity: a prospective, observational study in Greece -- Number of brain states in an N-body dynamical scenario according to the universal Bekenstein entropy bound -- Burden and sleeping disorders of family caregivers of Hemodialysis patients with Chronic Kidney Disease-End Stage. A cross-sectional study -- Quality of life in type 2 diabetes mellitus patients with neuropsychological deficits -- A framework for assessing the impact of information seeking behavior on cancer patients’ long-term prognosis -- Sleeping Disorders and Health Related Quality of Life in Hemodialysis patients with Chronic Renal Disease in Greece -- Subjective Quality of Life, Religiousness and Spiritual Experience in Greek Orthodox Christians: Data from Healthy Aging and Patients with Cardiovascular Disease -- Mini-Mental State Examination: Greek normative data stratified by age and education in a large sample of 925 community-dwelling healthy participants -- The role of the family in the care of Alzheimer patients -- Prevalence of Stroke Cases in Warangal, Telangana Region, India: A Hospital-Based Case Study -- Compliance of Patients with Acute Coronary Syndrome with treatment following their hospitalization from the Cardiac Coronary Unit -- Using a Virtual Reality Serious Game to Assess the Performance of Older Adults with Frailty -- Characteristics and survival rates in ward patients requiring evaluation by Intensivist in Greece.
    Kurzfassung: The 3rd World Congress on Genetics, Geriatrics, and Neurodegenerative Disease Research (GeNeDis 2018), focuses on recent advances in genetics, geriatrics, and neurodegeneration, ranging from basic science to clinical and pharmaceutical developments. It also provides an international forum for the latest scientific discoveries, medical practices, and care initiatives. Advanced information technologies are discussed, including the basic research, implementation of medico-social policies, and the European and global issues in the funding of long-term care for elderly people.
    Materialart: Online-Ressource
    Seiten: X, 155 p. 10 illus., 4 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030326371
    Serie: Advances in Experimental Medicine and Biology, 1196
    URL: https://doi.org/10.1007/978-3-030-32637-1
    DOI: 10.1007/978-3-030-32637-1
    DDC: 612.8
    Sprache: Englisch
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  • 57
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    Essentials of Cerebellum and Cerebellar Disorders : A Primer For Graduate Students (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Neuroanatomy. ; Neurophysiology. ; Developmental neurobiology. ; Cognitive neuroscience. ; Neuroscience. ; Neuroanatomy. ; Neurophysiology. ; Development of the Nervous System. ; Cognitive Neuroscience.
    Kurzfassung: This monograph, now in its 2nd edition with 31 new chapters and significant updates, is the first book of its kind written specifically for graduate students and clinicians. The monograph is based on the 4-volume treatise, Handbook of the Cerebellum and Cerebellar Disorders (Springer, 2013; 2nd edition: 2022), the definitive reference for scientists and neurologists in the field of cerebellar neurobiology and related areas. There have been fundamental advances in the basic science and clinical neurology of the cerebellum and its role in sensorimotor function and cognition. Essentials of the Cerebellum and Cerebellar Disorders makes this large and expanding body of knowledge readily accessible to trainees and clinicians alike. It is organized into easy to read and short chapters that are ideal for students and clinicians. The most common cerebellar disorders encountered in the clinic are covered. The editors are world leaders in the field, and the chapters are authored by an international panel of experts drawn from cerebellar laboratories and ataxia clinics throughout North America, Europe and Asia. Essentials provides a solid grounding in the field of cerebellar research and ataxiology from cerebellar cellular biology and circuity to clinical practice, and it serves as a springboard to a deeper appreciation of both the principles and the complexities of cerebellar neurobiology. Clinicians are expected to have a deep appreciation of cerebellar disorders, not only in specialized ataxia clinics but also in adult and pediatric neurology, neurosurgery, psychiatry and neuropsychology practices, and in outpatient and inpatient rehabilitation settings. This book is an indispensable resource for students and practitioners navigating the evolving field of cerebellar motor and cognitive neurology. It also links to the more expansive Handbook for those who need to explore the topics in this monograph in greater depth.
    Materialart: Online-Ressource
    Seiten: XIV, 742 p. 182 illus., 127 illus. in color. , online resource.
    Ausgabe: 2nd ed. 2023.
    ISBN: 9783031150708
    URL: https://doi.org/10.1007/978-3-031-15070-8
    DOI: 10.1007/978-3-031-15070-8
    DDC: 612.8
    Sprache: Englisch
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    Cerebellum as a CNS Hub (2021)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Neuroscience.
    Kurzfassung: Based on the 75th Fujihara Seminar held in December 2018 in Tokyo, Japan, this volume explores the latest research on the cerebellum. Contributors seek to examine the cerebellum's role as a unique hub for brain activity and discover new information about its purpose. The discussion is broad, ranging from evolutionary topics to therapeutic strategy and addresses both physiology and pathology. Subjects covered include anatomy, information processing, complex spikes, plasticity, modeling, and spinocerebellar ataxias. The volume is intended to set the stage for the future of cerebellar research and guide both basic and clinical researchers.
    Materialart: Online-Ressource
    Seiten: XI, 553 p. 136 illus. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030758172
    Serie: Contemporary Clinical Neuroscience,
    URL: https://doi.org/10.1007/978-3-030-75817-2
    DOI: 10.1007/978-3-030-75817-2
    DDC: 612.8
    Sprache: Englisch
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    New Discoveries in the Behavioral Neuroscience of Attention-Deficit Hyperactivity Disorder (2022)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Psychobiology. ; Human behavior. ; Pharmacology. ; Psychiatry. ; Pain medicine. ; Neuroscience. ; Behavioral Neuroscience. ; Pharmacology. ; Psychiatry. ; Pain Medicine.
    Beschreibung / Inhaltsverzeichnis: CLINICAL PROFILE AND TREATMENTS -- ADHD in children and adults: diagnosis and prognosis -- Treatment strategies -- Psychostimulants – treatment efficacy and problems -- Recent developments and future options for pharmacological treatments for ADHD -- GENETICS -- Genetics of ADHD (including CNVs) -- Genes , cognitive function and ADHD -- Epigenetics and ADHD -- CO-MORBIDITY -- ADHD and comorbid depression -- ADHD and autism -- Aggression and ADHD -- Obesity and ADHD (+ cytokines?) -- Sleep circadian rhythms and ADHD -- Substance misuse -- ASSESSING BRAIN FUNCTION / DYSFUNCTION -- EEG and ADHD (the skeptical view) -- Update on imaging – with connectivity -- Visual processing substrates for ADHD -- Cortical microstructure / connectivity -- ANIMAL AND IN VITRO STUDIES -- Critique of animal models -- Update on circuits for impulsive behaviour -- Zebrafish -- Update on DA transporter and ADHD -- Arousal, noradrenaline and ADHD -- FUTURE DIRECTIONS -- Stem cells for disease modelling -- Microbiome and ADHD -- Adult ADHD.
    Kurzfassung: New Discoveries in the Behavioral Neuroscience of Attention Deficit Hyperactivity Disorder reviews the latest developments in preclinical and clinical research of Attention Deficit Hyperactivity Disorder. As well as updating key chapters that were included in an earlier edition, this volume includes some new topics that are attracting a great deal of interest and point the way to new and promising directions for future research. The chapters follow five main themes: Current perspectives on the clinical profile of ADHD and its treatment, common co-occurring conditions, neurobiological studies examining brain function and genetics, animal and in vitro studies, and future directions. This combination of topics emphasises the translational relevance and validity of preclinical research so as to enable a better understanding of ADHD and to highlight the promising strategies for developing new treatments.
    Materialart: Online-Ressource
    Seiten: VIII, 501 p. 100 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031118029
    Serie: Current Topics in Behavioral Neurosciences, 57
    URL: https://doi.org/10.1007/978-3-031-11802-9
    DOI: 10.1007/978-3-031-11802-9
    DDC: 612.8
    Sprache: Englisch
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    Role of Micronutrients in Brain Health (2022)
    Singapore :Springer Nature Singapore :
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    Schlagwort(e): Neurosciences. ; Nervous system Diseases. ; Cognitive neuroscience. ; Developmental neurobiology. ; Nutrition   . ; Neuroscience. ; Neurological Disorders. ; Cognitive Neuroscience. ; Development of the Nervous System. ; Nutrition.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Micronutrients and Neurogenesis -- Chapter 2. Vit-E and Cognitive functions: What is the Interplay? -- Chapter 3. Microbiome and micronutrients -- Chapter 4. Iodine and Brain -- Chapter 5. Tocotrienol and Brain -- Chapter 6. Micronutrients and Depression -- Chapter 7. Micronutrients and Epilepsy -- Chapter 8. Iron Deficiency and brain cognitive functions -- Chapter 9. Micronutrients and PD -- Chapter 10. Malnutrition of Micronutrients and the brain disorders -- Chapter 11. Connections between micronutrients, cerebral monoamines and related brain disorders -- Chapter 12. Micronutrients and Autism -- Chapter 13. Edible Bird’s Nest as Brain Food -- Chapter 14. Phytochemicals as Micronutrients: What is Their Therapeutic Promise in the Management of Traumatic Brain Injury? -- Chapter 15. Phytochemicals as Micronutrients: What is Their Therapeutic Promise in the Management of Alzheimer’s Disease? -- Chapter 16. Nutrigenomics and Brain.
    Kurzfassung: This book comprehensively reviews the relationship between micronutrients and brain in health and diseases. It explains the relationship between micronutrients and brain functions, neurogenesis, and cognitive functions. The book also explores the relationship between micronutrients and brain disorders including depression, epilepsy, PD, and Autism. It further explores the recent advancements in understanding the important role of micronutrients as therapeutics in various brain disorders like TBI and AD. Lastly, it presents an overview of micronutrients as neuroprotective agents along with the main principles of nutrigenomics.
    Materialart: Online-Ressource
    Seiten: XVII, 308 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811664670
    Serie: Nutritional Neurosciences,
    URL: https://doi.org/10.1007/978-981-16-6467-0
    DOI: 10.1007/978-981-16-6467-0
    DDC: 612.8
    Sprache: Englisch
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    The Rosetta Stone of the Human Mind : Three Languages to Integrate Neurobiology and Psychology (2022)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Cognitive psychology. ; Neuropsychology. ; Psychiatry. ; Philosophy of mind. ; Neurology . ; Neuroscience. ; Cognitive Psychology. ; Neuropsychology. ; Psychiatry. ; Philosophy of Mind. ; Neurology.
    Beschreibung / Inhaltsverzeichnis: Learning the Languages -- Humanity’s Search for Mind and the Subject: A Brief Review of the Evolution of Neuropsychobiology -- An “Ideographic,” Suprapersonal Language of Rules and Universal Symbols: Alwyn Scott and Nonlinear Dynamics -- A “Demotic,” First-Person Language of the Individual and the Social System: Apuleius and the Myth of Psyche -- The Language of the Objective Observer: Gerald Edelman and Neurodarwinism: Antonio Damasio and the Feeling of Knowing -- Seeking the Understanding -- Consciousness -- The Unconscious -- The Database -- Affectivity -- The Neural/Mental Gap: Intuition, Self and Ego, a Trilingual Map -- Applying the Knowledge -- The Three Languages and Science: A New Scientific Paradigm? -- The Three Languages and Treatment -- The Psychotherapeutic Dialogue: Intersubjectivity -- The Role of a New Science for Psyche Upon Society and Culture.
    Kurzfassung: The study of the brain-mind complex has been hampered by the dichotomy between objective biological neuroscience and subjective psychological science. The two antithetical avenues of research are partly responsible for the failure to unravel the transformation of neural events into mental images: how matter becomes imagination, and vice versa; is the brain’s consciousness equivalent to Ego consciousness? Is the ego the self? In its new and updated edition, “The Rosetta Stone of the Human Mind: Three Languages to Integrate Neurobiology and Psychology” illustrates how the simultaneous use of the languages of neurobiology, of mathematics, and of the humanities, enriches the understanding of the neural and mental realms and adds new dimensions to our perception of neuropsychological events. Dr. Sanguineti shows how the two seemingly dichotomous approaches are similar in what they describe, and he explores how the awareness and application of these perspectives are helpful in getting a deeper theoretical grasp on major mental events, giving us a better understanding of individual minds, and fostering a more integrated therapeutic intervention. The intended readers include neuroscientists, psychiatrists, psychologists, and anyone interested in the human mind. Describes a model integrating biological neuroscience principles, subjective psychological science, and nonlinear physics and mathematics Offers a wide-ranging, holistic exploration of the mind and its conscious and unconscious realms, using myth, art, philosophy, neurobiology and basic sciences Introduces the future new paradigm for emergent science, the Poem, to replace the outdated classical reductionistic paradigm of the Machine.
    Materialart: Online-Ressource
    Seiten: XXII, 167 p. 25 illus., 6 illus. in color. , online resource.
    Ausgabe: 2nd ed. 2022.
    ISBN: 9783030864156
    URL: https://doi.org/10.1007/978-3-030-86415-6
    DOI: 10.1007/978-3-030-86415-6
    DDC: 612.8
    Sprache: Englisch
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    A Dictionary of Hallucinations (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Psychiatry. ; Neurology . ; Neuroscience. ; Psychiatry. ; Neurology.
    Beschreibung / Inhaltsverzeichnis: A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- V -- W -- X -- Y -- Z.
    Kurzfassung: The Dictionary of Hallucinations, second edition, is an alphabetical listing of issues pertaining to hallucinations and other misperceptions. They can be roughly divided into four categories: 1. Definitions of individual hallucinatory symptoms 2. Medical conditions and substances associated with the mediation of hallucinations 3. Historical figures who are known to have experienced hallucinations 4. Miscellaneous issues Each of the definitions of individual hallucinatory symptoms includes: a definition of the term its etymological origin the year of introduction (if known) a reference to the author or authors who introduced the term (if known) a description of the current use a brief explanation of the etiology and pathophysiology of the symptom at hand (if known) references to related terms references to the literature The second edition of A Dictionary of Hallucinations serves as a reference manual for neuroscientists, psychiatrists, psychiatric residents, psychologists, neurologists, historians of psychiatry, general practitioners, and academics dealing professionally with concepts of hallucinations and other sensory deceptions. This new edition provides updated information and references, and includes newly discovered hallucinations, bringing together contributions by other authorities within the field, with all the entries edited by Prof. Blom.
    Materialart: Online-Ressource
    Seiten: XXVI, 790 p. 604 illus., 364 illus. in color. , online resource.
    Ausgabe: 2nd ed. 2023.
    ISBN: 9783031252488
    URL: https://doi.org/10.1007/978-3-031-25248-8
    DOI: 10.1007/978-3-031-25248-8
    DDC: 612.8
    Sprache: Englisch
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    Proteins Associated with Neurodevelopmental Disorders (2022)
    Singapore :Springer Nature Singapore :
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    Schlagwort(e): Neurosciences. ; Proteins. ; Nervous system Diseases. ; Genetics. ; Neuroscience. ; Proteins. ; Neurological Disorders. ; Genetics.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Proteins Commonly Linked to Autism Spectrum Disorder -- Chapter 2. Protein Aggregation and Recycling -- Chapter 3. Neuron Membrane and Trafficking Protein Kinases (PKA&B) involved in ASD -- Chapter 4. Proteomic profiling in children with ASD -- Chapter 5. Molecular Protein biomarkers for developing diagnostics and therapeutic interventions.Gene Regulation in Autism. OR Neurodevelopmental Epigenomics -- Chapter 6. Chromatin and Epigenetic Regulation in ASD -- Chapter 7. Autism and the Scaffolding Protein Neurobeachin -- Chapter 8. Genomic Profiling in ADHD subjects -- Chapter 9. ADHD and Epigenetics Regulation -- Chapter 10. Proteomic Approach in ADHD -- Chapter 11. DHD and the Dopamine Transporter (DAT) -- Chapter 12. Protein Kinases involved in ADHD -- Chapter 13. ADHD and Cell Adhesion Molecule 1 – CAM 1 (CADM1 gene) -- Chapter 14. ASD and Cell Adhesion Molecule Astrotactin -- Chapter 15. Possible therapeutic interventions through proteins in ADHD.
    Kurzfassung: This book comprehensively reviews the proteins associated with neurodevelopmental disorders, including autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). It also discusses the interactions of the associated-proteins, like bromodomain-containing proteins (BCPs), kinases, synaptic proteins, scaffolding proteins, transcriptional factors, and DNA-binding proteins at the subcellular and molecular levels. The book also explores the potential of these proteins as a druggable target and a biomarker in the neurodevelopmental disorders. The book further explores the recent advancements in understanding the important role of epigenetic factors in predisposition to these diseases. Lastly, it presents genetic factors that lead to variation in gene expression in these diseases, disorders management via diet intervention and the future potential of stem cell therapy.
    Materialart: Online-Ressource
    Seiten: XV, 339 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811597817
    Serie: Nutritional Neurosciences,
    URL: https://doi.org/10.1007/978-981-15-9781-7
    DOI: 10.1007/978-981-15-9781-7
    DDC: 612.8
    Sprache: Englisch
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    Glutamate and Neuropsychiatric Disorders : Current and Emerging Treatments (2022)
    Cham :Springer International Publishing :
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    Schlagwort(e): Neurosciences. ; Neurology . ; Neuropsychology. ; Pharmacology. ; Neuropharmacology. ; Psychiatry. ; Neuroscience. ; Neurology. ; Neuropsychology. ; Pharmacology. ; Neuropharmacology. ; Psychiatry.
    Beschreibung / Inhaltsverzeichnis: Treatments Against Glutamatergic Excitotoxicity in Ischemic Stroke -- Definitions and Concepts of Stress -- Role of Glutamatergic Neurotransmission in the Pathophysiology of Stress-Related Disorders and Chronic Stress Response -- Current Glutamatergic Treatments and Future Directions for Glutamate-Based Management of Chronic Stress and Stress-Related Disorders -- The Role of the Glutamate System in Posttraumatic Stress Disorder and Glutamate-Based Treatments -- Glutamate in Migraine Neurobiology and Treatment -- Astrocyte Glutamate Transporter EAAT2 in Alzheimer Dementia -- The Glutamatergic System as a Target for the Development of New Pharmacological Treatments of Bipolar Disorder -- CNS Glutamate in Impulsive Aggression -- Glutamatergic Treatments for Parkinsons' Disease -- The Modulation of Glutamatergic Signaling as a Potential Therapeutic Strategy for Major Depression -- Glutamate-Based Treatment for Amyotrophic Lateral Sclerosis/Motor Neuron Disease -- Modulation of Glutamate for Chronic Pain Management -- Pharmacological Role of Glutamate Transporters in Substance Use Disorders -- Glutamate in Multiple Sclerosis: From Pathophysiology to Treatments -- The Role of Glutamate Dysregulation in the Etiology of ADHD -- Glutamate, Glutamatergic Drugs and Schizophrenia -- Glutamate and Epilepsy: An Insight from Temporal Lobe Epilepsy -- Glutamate Function in Anxiety Disorders and OCD: Evidence from Clinical and Translational Studies -- Modulators of Glutamatergic Signaling as Potential Treatments for Autism Spectrum Disorders.
    Kurzfassung: This volume provides a comprehensive overview of recent advances in targeting glutamate signaling for the treatment of major psychiatric and neurological disorders. It draws on the latest findings in glutamate neurobiology and offers valuable insights into the application of translational principles in neuroscience drug discovery and development. In each chapter, glutamate as a neurotransmitter, its receptors and transporters, and their interplay with other neurotransmitters and neurotrophic factors, are discussed in the context of a specific, highly prevalent and disabling CNS disease. Most recent and detailed information is provided on Ischemic Stroke, Chronic Stress, Major Depressive Disorder, Bipolar Disorder, Autism Spectrum Disorders (ASD), Posttraumatic Stress Disorder (PTSD), Alzheimer’s Dementia, Schizophrenia, Impulsive Aggression, Substance Use Disorders (SUD), Amyotrophic Lateral Sclerosis (ALS), Chronic Pain, Multiple Sclerosis, Parkinson’s Disease, Attention Deficit Hyperactivity Disorder (ADHD), Migraine, Epilepsy and Anxiety disorders. Moreover, the book includes an extensive overview of glutamatergic treatments already available on the market, and those which are currently in pharmaceutical drug development pipelines. The primary beneficiaries will be neurology and psychiatry specialists and residents, neuroscientists, neuropharmacologists, pharmaceutical industry and clinical research organization professionals, academics, and clinicians working with psychiatric and neurological patients with comorbidities such as cardiologists, pulmonologists, and endocrinologists. This book will also appeal to psychiatry and neurology subspecialists and clinicians working in neuroscience labs seeking an easy-to-understand yet comprehensive overview of contemporary evidence-based clinical insights backed by basic science (preclinical) research evidence. Given its scope, the book is also a unique and indispensable resource for both preclinical and clinical neuroscientists, medical advisors, and clinical research specialists in the pharmaceutical industry. In addition, it will appeal to neuroscience and neuropsychopharmacology students and guide them through the complexities of glutamate involvement in the pathophysiology of the most common debilitating brain diseases with high unmet medical needs.
    Materialart: Online-Ressource
    Seiten: XXXV, 600 p. 43 illus., 40 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030874803
    URL: https://doi.org/10.1007/978-3-030-87480-3
    DOI: 10.1007/978-3-030-87480-3
    DDC: 612.8
    Sprache: Englisch
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    Computational Modelling of the Brain : Modelling Approaches to Cells, Circuits and Networks (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Neurosciences. ; Neural circuitry. ; Bioinformatics. ; Computer science. ; Neuroscience. ; Neural Circuits. ; Computational and Systems Biology. ; Computer Science.
    Beschreibung / Inhaltsverzeichnis: PART I. Cellular Scale -- Chapter 1. Modelling Neurons in 3D at the Nanoscale -- Chapter 2. Modelling Dendrites and Spatially-Distributed Neuronal Membrane Properties -- Chapter 3. A User's Guide to Generalized Integrate-and-Fire Models -- Chapter 4. Neuron-glia Interactions and Brain Circuits -- Chapter 5. Short-term Synaptic Plasticity: Microscopic Modelling and (some) Computational Implications -- PART II. Molecular Scale -- Chapter 6. The Mean Field Approach for Populations of Spiking Neurons -- Chapter 7. Multidimensional Dynamical Systems with Noise -- Chapter 8. Computing Extracellular Electric Potentials from Neuronal Simulations -- Chapter 9. Bringing Anatomical Information into Neuronal Network Models -- PART III. Network Scale -- Chapter 10. Computational Concepts for Reconstructing and Simulating Brain Tissue -- Chapter 11. Reconstruction of the Hippocampus -- Chapter 12. Challenges for Place and Grid Cell Models -- Chapter 13. Whole-Brain Modelling: Past, Present, and Future.
    Kurzfassung: This volume offers an up-to-date overview of essential concepts and modern approaches to computational modelling, including the use of experimental techniques related to or directly inspired by them. The book introduces, at increasing levels of complexity and with the non-specialist in mind, state-of-the-art topics ranging from single-cell and molecular descriptions to circuits and networks. Four major themes are covered, including subcellular modelling of ion channels and signalling pathways at the molecular level, single-cell modelling at different levels of spatial complexity, network modelling from local microcircuits to large-scale simulations of entire brain areas and practical examples. Each chapter presents a systematic overview of a specific topic and provides the reader with the fundamental tools needed to understand the computational modelling of neural dynamics. This book is aimed at experimenters and graduate students with little or no prior knowledge of modelling who are interested in learning about computational models from the single molecule to the inter-areal communication of brain structures. The book will appeal to computational neuroscientists, engineers, physicists and mathematicians interested in contributing to the field of neuroscience. Chapters 6, 10 and 11 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com. .
    Materialart: Online-Ressource
    Seiten: XII, 359 p. 115 illus., 94 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030894399
    Serie: Cellular Neuroscience, Neural Circuits and Systems Neuroscience, 1359
    URL: https://doi.org/10.1007/978-3-030-89439-9
    DOI: 10.1007/978-3-030-89439-9
    DDC: 612.8
    Sprache: Englisch
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    Neurotoxicity of Aluminum (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Neurosciences. ; Pharmacology. ; Neuroscience. ; Pharmacology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1 Overview of the relationship between aluminum exposure and health of human being.-Chapter 2 The Chemistry of Human Exposure to Aluminum -- Chapter 3 Entry and Deposit of Aluminum in Brain -- Chapter 4 Aluminum as a CNS and immune system toxin across the life span.-Chapter 5 Occupational exposure to aluminum and cognitive impairment -- Chapter 6 Debated relationship between Exposure to Aluminum in Daily Life and Alzheimer’s Disease -- Chapter 7 Animal Model of Aluminum-Induced Alzheimer’s like Disease -- Chapter 8 Aluminum-induced AD-like Pathological Features.-Chapter 9 Aluminum induced neural cells death -- Chapter 10 Aluminum-Induced Electrophysiological Variation, Synaptic Plasticity Impairment, and Related Mechanism.-Chapter 11 Cross Talk Between Aluminum and Genetic Susceptibility -- Chapter 12 Epigenetic modification in aluminum-induced neuron death and synaptic impairment -- Chapter 13 Neurotoxic effects of aluminum and aluminum alloy nanoparticles(TBD) -- Chapter 14 Alumina nanoparticles induced neurotoxic and neurodevelopmental toxic effects.
    Kurzfassung: This book reviews the scientific literature and the authors’ own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer’s disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, its relation to neurofibrillary tangles and amyloid beta—the pathological features of AD, and the possible mechanism of aluminum inducing these pathological features. Further, the book stresses the importance of aluminum’s complex speciation chemistry in relation to biology, and details aluminum’s mechanism in oxidative stress and cell death, especially in connection with apoptosis and necroptosis. The electrophysiological variation and synaptic plasticity induced by aluminum are covered, while the metal’s debatable role in AD and the cross-talk between aluminum and genetic susceptibility are also discussed, and more recently the relationship between aluminum-induced epigenetic modification on DNA and non-coding RNAs and neuron death and synaptic impairment. The second edition updates eight chapters according to the most recent researches. Content about aluminum-induced AD-like pathological features, neurotoxic effects of aluminum and aluminum alloy nanoparticles(TBD) and alumina nanoparticles induced neurotoxic and neurodevelopmental toxic effects is also added. In closing, this book provides readers with a systematic summary of aluminum neurotoxicity.
    Materialart: Online-Ressource
    Seiten: XVIII, 313 p. 1 illus. , online resource.
    Ausgabe: 2nd ed. 2023.
    ISBN: 9789819915927
    URL: https://doi.org/10.1007/978-981-99-1592-7
    DOI: 10.1007/978-981-99-1592-7
    DDC: 612.8
    Sprache: Englisch
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    Autism Spectrum Disorder and Alzheimer's Disease : Advances in Research (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Neurosciences. ; Neurology . ; Neuroscience. ; Neurology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Behavioral pathophysiology and psychological implications for sleep disorder in dementia -- Chapter 2. Mitochondrial dysfunction is a key player in the pathogenesis of autism spectrum disorders and Alzheimer's disease -- Chapter 3. The pathogenesis and complications associated with autism spectrum disorder and Alzheimer ’s disease: A Comparative study -- Chapter 4. Impact of common natural compound in the treatment of Alzheimer's disease -- Chapter 5. Mapping a link between mercury-toxicity and Alzheimer disease -- Chapter 6. Drug therapy of Alzheimer's disease: Cholinesterase inhibitors, NMDA Antagonists -- Chapter 7. Therapeutic potential of polyphenols in Alzheimer's therapy: Broad-spectrum and minimal side effects as key aspects -- Chapter 8. recent advances in Alzheimer's disease in relation to cholinesterase inhibitors and NMDA receptor antagonists -- Chapter 9. Genetic basis of psychotic illnesses: A comprehensive overview RNA Secondary structures in neurodegeneration -- Chapter 10. RNA secondary structures in neurodegeneration -- Chapter 11. Immunotherapy: An approach to treat Alzheimer's disease and autism spectrum disorders -- Chapter 12. Alzheimer's disease (AD) - Physiological barriers for therapy and Nanotechnological applications in the treatment -- Chapter 13. Autism spectrum disorder relationship between sleep and behavior: The effect of sleep variability exploration -- Chapter 14. Role of impaired ABC transporters in Alzheimer’s disease -- Chapter 15. Cognitive impairment and rehabilitation of children and adults with autism spectrum disorder.
    Kurzfassung: This book talks about the multidimensional biological etiology of Alzheimer’s disease and autism spectrum disorder which leads to distinctive ways of perception, thinking and learning in affected individuals. It provides a deeper emphasis on the need for early diagnosis, continuous assessment of patients and the proper educational methods and environment required towards enabling people affected with these disorders capable of evolving and learning. This book explores alternative solutions for autism spectrum disorder based on the theory of brain plasticity, the relationship between the gut microbiota and the central nervous system along with genetic factors and toxic metal exposures which are responsible for the oxidative damage resulting in a decreased ability of the patients to use objects or response to auditory stimuli. It also identifies and provides the latest research towards dealing with memory loss, which is the first sign of cognitive impairment followed by behavioral disturbances. These symptoms are associated with a rigorous neuronal decline and the appearance of two brain lesions, senile plaques and neurofibrillary tangles, which are mainly composed of Aβ and hyper phosphorylated tau protein respectively. This book also provides the latest research towards reducing autism disorder severity such as targeting the disease with symptomatic treatments such as cholinesterase inhibitors, NMDA receptor antagonist, β-secretase and γ-secretase inhibitors, α-secretase stimulators, tau inhibitors, immunotherapy, nutraceuticals, and nano drugs. This book will not only be a good resource for professors and lecturers teaching in the area of neuroscience, medicine, biochemistry, neuroinformatics, and nanotechnology, etc. but also for professionals working in the field of occupational therapy and geriatric clinics and rehabilitation.
    Materialart: Online-Ressource
    Seiten: XI, 314 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811645587
    URL: https://doi.org/10.1007/978-981-16-4558-7
    DOI: 10.1007/978-981-16-4558-7
    DDC: 612.8
    Sprache: Englisch
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    Vertebrate Motoneurons (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Neurosciences. ; Neuroscience.
    Beschreibung / Inhaltsverzeichnis: Establishing the molecular and functional diversity of spinal motoneurons -- Chloride homeostasis in developing motoneurons -- Normal development and pathology of motoneurons: anatomy, electrophysiological properties, firing patterns and circuit connectivity -- Homeostatic regulation of motoneuron properties in development -- Homeostatic plasticity of the mammalian neuromuscular junction -- Diversity of mammalian motoneurons and motor units -- Synaptic projections of motoneurons within the spinal cord -- Recruitment of motoneurons -- Electrical properties of adult mammalian motoneurons.-The cellular basis for the generation of firing patterns in human motor units -- Motoneuronal regulation of central pattern generator and network function -- Extraocular motoneurons and neurotrophism -- Motoneuron diseases -- Electrical and morphological properties of developing motoneurons in postnatal mice and early abnormalities in sod1 transgenic mice -- From physiological properties to selective vulnerability of motor units in amyotrophic lateral sclerosis. .
    Kurzfassung: This book aims to provide a comprehensive and timely review of new findings in motoneuron research. Recent findings have revealed that motoneurons are more complex and have more extensive functions than previously imagined. Some of the molecular and genetic pathways that orchestrate the development of motoneurons have been discovered, as have the mechanisms responsible for the selective innervation of muscles by specific pools of motoneurons. These novel findings are revolutionizing ideas about the function of motoneurons and have important implications for motoneuron disease. Chapters from several of the foremost figures in the field are included in this book and will emphasize how basic science is the engine driving the discovery of novel treatments for degenerative motoneuron diseases. Cutting edge developments in the use of pluripotent stem cells to correct motoneuron disease will be also be covered. This book would be useful to students of basic motoneuron physiology, locomotor behavior and motor control. This book would also be of interest to professional neuroscientists, neurologists, and neurosurgeons.
    Materialart: Online-Ressource
    Seiten: XII, 400 p. 81 illus., 64 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031071676
    Serie: Advances in Neurobiology, 28
    URL: https://doi.org/10.1007/978-3-031-07167-6
    DOI: 10.1007/978-3-031-07167-6
    DDC: 612.8
    Sprache: Englisch
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    Nutrition and Psychiatric Disorders (2022)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Neurosciences. ; Cognitive psychology. ; Nutrition   . ; Neuropsychology. ; Neuroscience. ; Cognitive Psychology. ; Nutrition. ; Neuropsychology.
    Beschreibung / Inhaltsverzeichnis: SECTION I Food, Brain function, and Behavior- Chapter 1: Food and brain development (Ramya Nadig) -- Chapter 2: Nutrition and brain functions in Health and Disease (Heba Mansour) -- Chapter 3: Nutrition, cognitive functions, and emotions (Rasoul Ghasemi) -- Chapter 4: Ketogenic diet: Implications for treatment and injury in neuropsychiatry and motor functioning (fatima dakroub) -- Chapter 5: Effects of malnutrition on brain development (Pranshul Sethi) -- Chapter 6: Nutrition, neurotransmitters, and behavior (Sumit Srivastav) -- Chapter 7: OMICS in Schizophrenia and Alzheimer’s Disease (Sumit Srivastav) -- SECTION II Psychiatric disorders related to nutrition: deficiency or overload -- Chapter 8: Effects of Depression and Antidepressant Therapy on Serum Zinc Levels (Samer El Hayek) -- Chapter 9: Nutrition and Depression (Ramdas Ransing) -- Chapter 10: Nutritional Deficiencies in Obsessive-Compulsive Disorder and Possible Treatment Interventions (Samer El Hayek) -- Chapter 11: Caffeine, Mental wellbeing, and Psychiatric Disorders (Ahmed Radwan) -- Chapter 12: Biopsychology of chocolate craving (Laura Orsolini) -- Chapter13: Food addiction (Samer El Hayek) -- Chapter 14: Nutrition and Anxiety disorders (Ramli Musa) -- Chapter 15: Nutrition and substance use disorder (Zehra Batool) -- Chapter 16: Nutrition and Psychiatric Disorders: Focus on Schizophrenia (Heba Mansour) -- Chapter 17: High fat diet and psychiatric disorders: what is the interplay? (Pranshul Sethi).
    Kurzfassung: The book comprehensively reviews the role of nutrition in psychiatric disorders. It provides mechanistic insights into the effects of nutrition on metabolic pathways, mitochondrial nutrients, neurodegeneration and CNS disorders, cell signaling, and neuronal functions. The book further highlights the role of diet in preventing and treating mental health and modifying drug treatment effects. Further, it explores the relationship between nutrition and psychiatric disorders, including depression, autism, anxiety, Attention-Deficit / Hyperactivity Disorder, and OCD. The book further explores the recent advancements in understanding the important role of nutrients as therapeutics in various psychiatric disorders. Lastly, it presents an overview of nutrients as neuroprotective agents along with the main principles of nutrigenomics. The book is essential reading for neuroscientists interested interest in food therapeutic strategies.
    Materialart: Online-Ressource
    Seiten: XVIII, 383 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9789811950216
    Serie: Nutritional Neurosciences,
    URL: https://doi.org/10.1007/978-981-19-5021-6
    DOI: 10.1007/978-981-19-5021-6
    DDC: 612.8
    Sprache: Englisch
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    Biomarkers for Huntington's Disease : Improving Clinical Outcomes (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Neurosciences. ; Neurology . ; Neurophysiology. ; Neuropharmacology. ; Neuroscience. ; Neurology. ; Neurophysiology. ; Neuropharmacology.
    Beschreibung / Inhaltsverzeichnis: Molecular Biomarkers.Somatic instability/Telomeres,- Genetic modifiers -- Current clinical trial biomarkers.-Pharmacodynamic biomarkers for Htt-lowering therapeutics.-Inflammatory biomarkers.-Sleep dysregulation markers.-Mitochondrial/Oxidative stress biomarkers.-Microbiomics -- Metabolomics.-Proteomics.-Transcriptomics.-Lipidomics.-Imaging marker overview.-Retinal imaging biomarkers -- MRI - non-invasive functional MRI measures -- The evolution of clinical trial methodology.-Digital biomarkers -- The future of telehealth -- Summary and future trends.
    Kurzfassung: Huntington’s disease (HD) is a fatal, inherited, neurodegenerative disorder, characterized by chorea, motor instabilities, psychiatric manifestations and cognitive decline. Early genetic testing provides an opportunity for clinical interventions aimed at delaying onset and/or slowing progression of disease; however, current treatments for HD are limited, with only two FDA-approved drugs available to manage chorea. Encouragingly, however, several disease-modifying treatment approaches are in the therapeutic pipeline, with more than 200 clinical studies, and many more preclinical studies, in the works. Robust and reliable biomarkers are needed to predict disease onset, monitor disease progression and assess treatment responses. More specifically, biomarkers to stratify patients for clinical trials and biomarkers to track drug efficacy will certainly lead to improved clinical trial design and success. This book represents the first book focused solely on biomarkers for HD and represents a distinct resource that will be informative, not only for clinicians and those involved in clinical trial design, but also for a wide range of neurodegenerative disease researchers. This edited volume is written by top leaders in the field, and takes a cross-disciplinary approach to cover a broad spectrum of biomarker types, in order to provide the latest advances in the development of biochemical, molecular, imaging and digital biomarkers that have been investigated for HD. With the ultimate goal of treating patients, the development of disease-associated biomarkers has never been more important.
    Materialart: Online-Ressource
    Seiten: XVI, 475 p. 42 illus., 39 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031328152
    Serie: Contemporary Clinical Neuroscience,
    URL: https://doi.org/10.1007/978-3-031-32815-2
    DOI: 10.1007/978-3-031-32815-2
    DDC: 612.8
    Sprache: Englisch
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    Human iPSC-derived Disease Models for Drug Discovery (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Neurosciences. ; Regenerative medicine. ; Stem cells. ; Neuroscience. ; Regenerative Medicine and Tissue Engineering. ; Stem Cell Biology.
    Beschreibung / Inhaltsverzeichnis: Part 1 General considerations -- Human iPS for clinical applications and cellular products -- 3D-printed iPS disease models -- Part 2 CNS iPSC and organoids -- iPS-derived neurons and brain organoids from patients (brain) -- iPS-derived RGCs (eye) -- iPS-derived glia (brain) -- iPSC to model blood-brain barrier endothelial cells -- Part 3 iPSC-derived nociceptive neurons -- IPSC-based peripheral nerve modeling -- Part 4 Non-neuronal specialized cell types -- iPSC-based drug screening of differentiated cardiomyocyte subtypes -- iPSC-based cardiac disease modeling: from cell to tissue -- iPSC-derived corneal endothelial cell -- iPSC-derived trabecular meshwork (eye) -- iPSC for in vitro disease modeling of diabetes.
    Kurzfassung: Since their development a decade ago, human induced pluripotent stem cells (iPSC) have revolutionized the study of human disease, given rise to regenerative medicine technologies, and provided exceptional opportunities for pharmacologic research. These cells provide an essentially unlimited supply of cell types that are difficult to obtain from patients, such as neurons or cardiomyocytes, or are difficult to maintain in primary cell culture. iPSC can be obtained from patients afflicted with a particular disease but, in combination with recently developed gene editing techniques, can also be modified to generate disease models. Moreover, the new techniques of 3 Dimensional printing and materials science facilitate the generation of organoids that can mirror organs under disease conditions. These properties make iPSC powerful tools to study how diseases develop and how they may be treated. In addition, iPSC can also be used to treat conditions in which the target cell population has been lost and such regenerative approaches hold great promise for currently untreatable diseases, including cardiac failure or photoreceptor degenerations.
    Materialart: Online-Ressource
    Seiten: VIII, 332 p. 100 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031423499
    Serie: Handbook of Experimental Pharmacology, 281
    URL: https://doi.org/10.1007/978-3-031-42349-9
    DOI: 10.1007/978-3-031-42349-9
    DDC: 612.8
    Sprache: Englisch
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    Structural Geological Atlas (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Geology. ; Mineralogy. ; Geology. ; Mineralogy.
    Beschreibung / Inhaltsverzeichnis: Barmer basin -- Deccan Traps -- Lesser Himalaya -- Ladakh Himalaya -- Aravalli.
    Kurzfassung: This book presents more than 600 eye-catching structural geological photographs and explanatory descriptions, from different Indian terrains. This book will enable easy identification of deformation features, one of the most important tasks in structural geology at the meso- and micro-scales. The book focuses on ductile and brittle shear sense indicators. This book suits for the undergraduate and graduate geoscience students. The book will be of considerable interest to tectonicians and structural geologists, given the enormous international importance of Indian terrains for exploration and other purposes.
    Materialart: Online-Ressource
    Seiten: VII, 623 p. 609 illus., 608 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811398254
    URL: https://doi.org/10.1007/978-981-13-9825-4
    DOI: 10.1007/978-981-13-9825-4
    DDC: 551
    Sprache: Englisch
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    Transformation Processes of Metals in Urban Road Dust : Implications for Stormwater Reuse (2020)
    Singapore :Springer Nature Singapore :
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    Schlagwort(e): Pollution. ; Water. ; Hydrology. ; Engineering geology. ; Pollution. ; Water. ; Geoengineering.
    Beschreibung / Inhaltsverzeichnis: Chapter 1: Metals in urban stormwater environments -- Chapter 2: Research design -- Chapter 3: Metal transformation and stormwater quality -- Chapter 4: Risk evaluation based on the metal transformation and bioavailability -- Chapter 5: Practical implications and recommendation for future research -- Appendices -- Index.
    Kurzfassung: This book discusses the physicochemical changes (transformations) that metals deposited on urban road surfaces undergo during dry weather periods, in order to provide insights into their potential impacts on stormwater quality. Based on extensive field experiments, and laboratory and data analyses, it examines transformation characteristics of metals with respect to the particle size of road dust, antecedent dry days and land uses. Further, it proposes a new risk-assessment methodology, improving the original human health-risk indices based on the transformation characteristics and potential bioavailability of metals in order to evaluate the risks posed by metals in stormwater. This book is of interest to researchers and decision-makers developing appropriate pollution mitigation measures to enhance the quality of stormwater, targeting the effective reuse of stormwater in urban areas.
    Materialart: Online-Ressource
    Seiten: VI, 50 p. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811520785
    Serie: SpringerBriefs in Water Science and Technology,
    URL: https://doi.org/10.1007/978-981-15-2078-5
    DOI: 10.1007/978-981-15-2078-5
    DDC: 363.73
    Sprache: Englisch
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    Empty Buckets and Overflowing Pits : Urban Water and Sanitation Reforms in Sub-Saharan Africa – Acknowledging Decline, Preparing for the Unprecedented Wave of Demand (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pollution. ; Refuse and refuse disposal. ; Sociology, Urban. ; Economic policy. ; Developmental psychology. ; Medical sciences. ; Pollution. ; Waste Management/Waste Technology. ; Urban Sociology. ; Economic Policy. ; Developmental Psychology. ; Health Sciences.
    Beschreibung / Inhaltsverzeichnis: Part 1: Urban Water and Sanitation (W+S) - Separating fiction from reality -- Chapter 1. Introduction to urban W+S in the developing world -- Chapter 2. Considerations for general W+S issues -- Chapter 3. Beyond the usual debate -- PART 2: Design and validation of the sector development model -- Chapter 4. An effective orientation and approach for development -- Chapter 5. What sector reforms in four countries teach us? -- Chapter 6. Reasons for the different reform outcomes in the four countries -- Part 3: At least full buckets and clear pits on the way forward -- Chapter 7. Ending the ‘urban W+S divide’ by serving the poor -- Chapter 8. Conclusions: The quintessence of W+S sector reforms in Sub-Saharan Africa -- Chapter 9. Recommendations: Guidance to master the coming wave of challenges.
    Kurzfassung: This book provides a multi-level and multi-dimensional insight into urban water and sanitation development by analyzing sector reforms in Africa. With the recent events in mind - water shortages in Cape Town, widespread cholera in Haiti, mass-migration from low-income countries, etc. – it elaborates a pressing topic which is directly linked to the precarious living conditions of the urban poor in the developing countries. It is urgent to acknowledge the proposed findings and recommendations of the book which will help to improve the situation of potential refugees in their home countries with a realistic vision for the development of the most basic of all life supporting services. So many efforts to reverse the negative trend in water and sanitation development have failed or targets have been repeatedly missed by far without notable consequences for decision makers on different levels and institutions. It has unnecessarily consumed many young lives, contributed to keep billions in poverty until today and fostered discrimination of women. The knowledge gap and the confusion in the sector lined out in the book becomes evident when a national leader in a low-income country declares a state of emergency in urban water and sanitation while at the same time global monitoring publishes an access figure for urban water of over 90% for the same country. It is time to change this with an effective sector development concept for our partner countries and a more realistic discourse on global level. The book argues for a sweeping rethinking and combines extended local knowledge, lessons learned from history in advanced countries and thorough research on reforms in Francophone and Anglophone developing countries. This was possible because the writer was working in Sub-Saharan partner countries for almost 30 years as an integrated long term advisor in different sector institutions (ministry, regulator, financing basket and different sizes of utilities) and had the opportunity to cooperate closely with the main development partners. The reader has the opportunity to obtain a comprehensive understanding of how the sector works and sector institutions in low-income countries function and can discover the reasons behind success and failures of reforms. The book also covers issues which have a significant influence on urban water and sanitation development but are hardly the subject of discussions. It helps to make the shortcomings of the water and sanitation discourse more apparent and assist institutions to move beyond their present perceptions and agendas. All of this makes the book different from other literature about urban water and sanitation in the developing world.
    Materialart: Online-Ressource
    Seiten: XXII, 285 p. 24 illus., 3 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030313838
    Serie: Springer Water,
    URL: https://doi.org/10.1007/978-3-030-31383-8
    DOI: 10.1007/978-3-030-31383-8
    DDC: 363.73
    Sprache: Englisch
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    Online-Ressource
    Glaciers and Ice Sheets in the Climate System : The Karthaus Summer School Lecture Notes (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Geology. ; Climatology. ; Environment. ; Physical geography. ; Geology. ; Climate Sciences. ; Environmental Sciences. ; Physical Geography.
    Beschreibung / Inhaltsverzeichnis: Flow of ice -- Thermal structure -- Basal processes -- Tidewater glaciers -- Ice shelves D ocean interaction -- Polar meteorology -- Mass balance -- Numerical methods -- Inverse modeling -- Analytic ice sheet models and climate change -- Firn -- Ice cores -- Remote sensing -- Geophysics -- Geodynamics -- Paleo-ice sheets -- Geomorphology -- Glacier fluctuations -- Tropical glaciers -- Historical glaciology.
    Kurzfassung: Our realisation of how profoundly glaciers and ice sheets respond to climate change and impact sea level and the environment has propelled their study to the forefront of Earth system science. Aspects of this multidisciplinary endeavour now constitute major areas of research. This book is named after the international summer school held annually in the beautiful alpine village of Karthaus, Northern Italy, and consists of twenty chapters based on lectures from the school. They cover theory, methods, and observations, and introduce readers to essential glaciological topics such as ice-flow dynamics, polar meteorology, mass balance, ice-core analysis, paleoclimatology, remote sensing and geophysical methods, glacial isostatic adjustment, modern and past glacial fluctuations, and ice sheet reconstruction. The chapters were written by thirty-four contributing authors who are leading international authorities in their fields. The book can be used as a graduate-level textbook for a university course, and as a valuable reference guide for practising glaciologists and climate scientists.
    Materialart: Online-Ressource
    Seiten: XXVII, 530 p. 283 illus., 214 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030425845
    Serie: Springer Textbooks in Earth Sciences, Geography and Environment,
    URL: https://doi.org/10.1007/978-3-030-42584-5
    DOI: 10.1007/978-3-030-42584-5
    DDC: 551
    Sprache: Englisch
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  • 76
    Online-Ressource
    Online-Ressource
    Sustainable Groundwater Management : A Comparative Analysis of French and Australian Policies and Implications to Other Countries (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Geology. ; Environmental management. ; Power resources. ; Environment. ; Water. ; Hydrology. ; Geology. ; Environmental Management. ; Natural Resource and Energy Economics. ; Environmental Sciences. ; Water.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Sustainable Groundwater Management in France and Australia: Setting Extraction Limits, Allocating Rights and Reallocation -- Chapter 2. Groundwater in France: Resources, Use and Management Issues -- Chapter 3. Groundwater Policy in France: From Private to Collective Management -- Chapter 4. Groundwater Management Planning at the River Basin District Level: Comparative Analysis of the Adour-Garonne and Loire-Bretagne River Basins -- Chapter 5. Lessons from Twenty Years of Local Volumetric Groundwater Management: The case of the Beauce Aquifer, Central France -- Chapter 6. Groundwater in Australia: Occurrence and Management Issues -- Chapter 7. The Evolution of Groundwater Management Policy in the States of Australia -- Chapter 8. Developing a Coordinated Groundwater Management Plan for the Interstate Murray-Darling Basin -- Chapter 9. Information Systems for Sustainable Management of Groundwater Extraction in France and Australia -- Chapter 10. The Challenge of Making Ground-water Visible: A Review of Communication Approaches and Tools in France -- Chapter 11. Conceptual Approaches, Methods and Models used to Assess Abstraction Limits for Unconfined Aquifers in France -- Chapter 12. Setting Sustainable Abstraction Limits in Confined Aquifers: Example from Deep Confined Aquifers in the Bordeaux Region, France -- Chapter 13. A tool to Determine Annual Ground-Water Allocations in the Tarn-et-Garonne Alluvial Aquifer (France) -- Chapter 14. Conceptual Approaches, Methods and Models used to Assess Extraction Limits in Australia: From Sustainable to Acceptable Yield -- Chapter 15. Case Study: An Integrated Approach to Determining Sustainable Abstraction Limits in Perth’s North West Urban Growth Corridor -- Chapter 16. Using Resource Condition Limits to Define Groundwater Management Objectives in the Barossa Valley, South Australia -- Chapter 17. Reducing Entitlements when Groundwater has been Over-allocated: Policy Issues and Options -- Chapter 18. Developing Substitution Resources as Compensation for Reduced Groundwater Entitlements: The Case of the Poitou Marshes (France) -- Chapter 19. New Approaches for Allocation Reductions and Groundwater Salinity Management in South Australia -- Chpater 20. Reducing Groundwater Entitlements in the Lower Murrumbidgee Groundwater Management Area -- Chapter 21. Development of Groundwater Markets in Australia: Insights from Victoria in the Murray Darling Basin -- Chapter 22. Groundwater Regulation, Compliance and Enforcement: Insights on Regulators, Regulated Actors and Frameworks in New South Wales, Australia -- Chapter 23. Compliance and Enforcement: the Achilles Heel of French Water Policy -- Chapter 24. The Role of Sectoral Policies to Restore Groundwater Balance: The Impact of Agricultural Policies on Irrigation Water Demand in France -- Chapter 25. Groundwater Management Lessons from Chile -- Chapter 26. California’s 2014 Sustainable Groundwater Management Act – From the Back Seat to the Driver Seat in the (Inter)National Groundwater Sustainability Movement -- Chapter 27. Changing from Unrestricted access to Sustainable Abstraction Management Regimes: Lessons Learnt from France and Australia. .
    Kurzfassung: This book describes and analyses the diversity of possible approaches and policy pathways to implement sustainable groundwater development, based on a comparative analysis of numerous quantitative management case studies from France and Australia. This unique book brings together water professionals and academics involved for several decades in groundwater policy making, planning or operational management to reflect on their experience with developing and implementing groundwater management policy. The data and analysis presented accordingly makes a significant contribution to the empirical water management literature by providing novel, real world insights unpublished elsewhere. The originality of the contributions also lies in the different disciplinary perspectives (hydrogeology, economics, planning and social sciences in particular) adopted in many chapters. The book offers a unique comparative analysis of France, Australia and experiences in countries such as Chile and the US to identify similarities, but also fundamental differences, which are analysed and presented as alternative policy options – these differences being mainly related to the role of the state, the community and market mechanisms in groundwater management.
    Materialart: Online-Ressource
    Seiten: XVII, 562 p. 149 illus., 143 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030327668
    Serie: Global Issues in Water Policy, 24
    URL: https://doi.org/10.1007/978-3-030-32766-8
    DOI: 10.1007/978-3-030-32766-8
    DDC: 551
    Sprache: Englisch
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  • 77
    Online-Ressource
    Online-Ressource
    Technological and Modern Irrigation Environment in Egypt : Best Management Practices & Evaluation (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pollution. ; Agriculture. ; Environmental management. ; Environment. ; Geographic information systems. ; Sustainability. ; Pollution. ; Agriculture. ; Environmental Management. ; Environmental Sciences. ; Geographical Information System. ; Sustainability.
    Beschreibung / Inhaltsverzeichnis: An Overview of Modern Irrigation system in Egypt -- Irrigation: Water Resources, Types and Common Problems in Egypt -- Need for Irrigation System Evaluation -- Evolution of irrigation system, tools and Technologies -- Smart Sensing System for Precision Irrigation -- Development of Recent Information on Irrigation Technology and Management.
    Kurzfassung: This book gathers contributions on modern irrigation environments in Egypt from an environmental and agricultural perspective. Written by leading experts in the field, it discusses a wide variety of modern irrigation problems. In the context of water resources management in Egypt, one fundamental problem is the gap between growing water demand and limited supply. As such, improving irrigation systems and providing farmers with better control over water are crucial to increasing productivity. The book presents state-of-the-art technologies and techniques that can be effectively used to address a range of problems in modern irrigation, as well as the latest research advances. Focusing on water sensing and information technologies, automated irrigation technologies, and improved irrigation efficiency. It brings together a team of experts who share their personal experiences, describe the various applications, present recent advances, and discuss possibilities for interdisciplinary collaboration and implementing the techniques covered.
    Materialart: Online-Ressource
    Seiten: X, 369 p. 66 illus., 45 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030303754
    Serie: Springer Water,
    URL: https://doi.org/10.1007/978-3-030-30375-4
    DOI: 10.1007/978-3-030-30375-4
    DDC: 363.73
    Sprache: Englisch
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  • 78
    Online-Ressource
    Online-Ressource
    Mineral Micro-Geochemistry Constraints on Petrogenesis and Genesis of Gold Deposit (2021)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Geology. ; Mineralogy. ; Geochemistry. ; Geology. ; Mineralogy. ; Geochemistry.
    Beschreibung / Inhaltsverzeichnis: Introduction -- Geological setting -- Micro-geochemistry of clinopyroxene of the mafic dykes in the Jiaodong peninsula: Implications for petrogenesis and geodynamic -- Micro-geochemistry of pyrite and gold mineral in Jiaodong gold deposits: Implications for genesis of gold deposit.
    Kurzfassung: Minerals respond texturally and compositionally to changing magmatic environments and preserve a wealth of information regarding magmatic processes and compositions in their crystal-growth stratigraphy. This book reports the detailed petrography and in-situ geochemistry of the clinopyroxene phenocrysts of the mafic dykes in the Jiaodong Peninsula, southeastern North China Craton, including in-situ determinations of major elements, trace elements, Sr isotopic compositions, and H2O contents with further constraints on the petrogenesis and geodynamics of the mafic dykes. Systematic analyses of mineralogical, major, and trace elements, Sr–Nd isotopes, and in-situ S isotopes on the pyrite of the main gold-bearing mineral assemblages and visible gold were conducted, aiming to explore the source of ore-forming materials and the process of Au element migration and deposition. The geodynamic setting of mineralization in the studied region is also summarized.
    Materialart: Online-Ressource
    Seiten: VIII, 203 p. 63 illus., 59 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9789811610226
    URL: https://doi.org/10.1007/978-981-16-1022-6
    DOI: 10.1007/978-981-16-1022-6
    DDC: 551
    Sprache: Englisch
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  • 79
    Online-Ressource
    Online-Ressource
    Geology of the Cayman Islands : Evolution of Complex Carbonate Successions on Isolated Oceanic Islands (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Geology. ; Water. ; Hydrology. ; Sedimentology. ; Earth sciences. ; Geography. ; Geology. ; Water. ; Sedimentology. ; Earth Sciences. ; Geography.
    Beschreibung / Inhaltsverzeichnis: Introduction -- Tectonic Setting of Cayman Islands -- Stratigraphic framework -- The Bluff Group -- The Ironshore Formation -- Modern marine sediments of the Cayman Islands -- Dolomitization of the Bluff Group -- Karst and caves -- Phosphates, terra rossa and mangrove peat -- Modern Hydrology -- Summary Information Database.
    Kurzfassung: Grand Cayman, Little Cayman, and Cayman Brac are, in reality, the summits of independent fault blocks that rise from the depths of the Caribbean Sea. This book traces the geological evolution of these islands over the last 30 to 35 million years. The balance between deposition of carbonate sediments and karst development of the exposed land was dictated by the interaction between ever-changing sea levels and vertical tectonic movement of the fault blocks. Today, drinking water needed for the ever-increasing populations of the islands is supplied largely by desalinization plants that are located in accord with a detailed knowledge of the bedrock. This book is based on an extensive data base that has been assembled over the last 40 years of field work and laboratory analyses. Noteworthy aspects of this database include: Approximately 60 visits to the islands over last 40 years – sampling and documentation of virtually every accessible outcrop on the islands (including some that no longer exist). Most samples have been fully documented petrographically and geochemically. Data from 120 wells that have been drilled to depths up to 245 m (most less than 125 m). Wells have been cored and/or chip sampled. Full documentation of drilling histories, XRD analyses of samples, extensive geochemical analyses for major and minor elements, stable isotopes, 87Sr/86Sr ratios, and Rare Earth Elements from numerous samples. Mapping and sampling of modern sediments, including sediment cores, from most of the lagoons around Grand Cayman. Extensive thin section petrography, scanning electron microscope, and electron microprobe analyses of the dolostones and limestones that form the bedrock of the islands. Samples and data collected from numerous caves on Grand Cayman and Cayman Brac have been used to track their developmental history. Detailed analyses of phosphates collected from Little Cayman. Detailed analyses of terra rossa collected from each of the islands.
    Materialart: Online-Ressource
    Seiten: XIII, 291 p. 247 illus., 232 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031082306
    URL: https://doi.org/10.1007/978-3-031-08230-6
    DOI: 10.1007/978-3-031-08230-6
    DDC: 551
    Sprache: Englisch
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  • 80
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    Online-Ressource
    Seasonal Flood Forecasts and Warning Response Opportunities : ENSO Applications in Bangladesh (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Natural disasters. ; Environment. ; Physical geography. ; Environmental management. ; Natural Hazards. ; Environmental Sciences. ; Earth System Sciences. ; Environmental Management.
    Beschreibung / Inhaltsverzeichnis: TABLE OF CONTENTS Preface: Why ENSO-based seasonal forecasts are important in Bangladesh Acknowledgements -- About the author -- Chapter 1: Introduction—Seasonal Flood Potential in Bangladesh -- Chapter 2: Basin-wide Hydro-Meteorological Variability and Opportunity for Seasonal -- Forecasts in Bangladesh -- Chapter 3: History of Flood Forecasts and Early Warning in Bangladesh -- Chapter 4: Overview of Weather, ENSO, and Climate Scale -- Chapter 5: The El Niño-Southern Oscillation (ENSO) and Seasonal Flooding in Bangladesh -- Chapter 6: Seasonal Flood Potential in Bangladesh -- Chapter 7: Overview of Eastern, Mixed, and Central Pacific El Niño -- Chapter 8: Seasonal Sea Level Information and Flood Forecast Potential in Bangladesh -- Chapter 9: Consensus Seasonal Flood Forecasts and Warning Response in Bangladesh -- Chapter 10: ENSO Impacts, Applications, and Conclusions.
    Kurzfassung: This book explores the feasibility of using El Niño-Southern Oscillation (ENSO)-based forecasts and early warning systems to prevent losses from floods and droughts in Bangladesh. Despite advances in short-range flood forecasting and information dissemination systems in Bangladesh, the present system is less than satisfactory. This is due to short lead-time products, outdated dissemination networks, and lack of direct feedback from the end-user. One viable solution is to produce long-lead seasonal forecasts—the demand for which is significantly increasing in Bangladesh— and disseminate these products through appropriate channels. As observed in other regions, the success of seasonal forecasts, in contrast to short-term forecasts, depends on consensus among the participating institutions. Therefore, the primary objective of the book is to revisit and modify the framework of an ideal warning response system for issuance of consensus seasonal flood forecasts in Bangladesh. The book discusses issues related to the 5-stage Flood Forecasts, Warning, and Response System (FFWRS) and emphasizes the role of the seasonal ‘Climate Outlook Forum (COF)’ in Bangladesh. The book also identifies ways to improve forecasting and early warning systems by utilizing ENSO-based climate data and models, and discusses a comprehensive and participatory approach to seasonal flood hazard management in Bangladesh. Several successful case examples of ENSO-based seasonal forecasts and early warning systems from other ENSO-sensitive regions have been documented. The primary audience includes academics and students, government policymakers, engineers, and business leaders.
    Materialart: Online-Ressource
    Seiten: XXX, 201 p. 84 illus., 56 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783031178252
    Serie: Disaster Risk Reduction, Methods, Approaches and Practices,
    URL: https://doi.org/10.1007/978-3-031-17825-2
    DOI: 10.1007/978-3-031-17825-2
    DDC: 551
    Sprache: Englisch
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  • 81
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    Online-Ressource
    Water Quality Index Prediction Using Multiple Linear Fuzzy Regression Model : Case Study in Perak River, Malaysia (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pollution. ; Water. ; Hydrology. ; Computational intelligence. ; Pollution. ; Water. ; Computational Intelligence.
    Beschreibung / Inhaltsverzeichnis: Introduction -- Fuzzy Multiple Linear Regression -- Water Quality Index (WQI) -- Data Collection and Study Sites -- Water Quality Index Using Fuzzy Regression.
    Kurzfassung: This book addresses the prediction of the Water Quality Index (WQI) at Perak River, State of Perak, Malaysia, using a fuzzy multiple linear regression model to tackle the uncertainty in the measurements of six key parameters – dissolved oxygen (DO), biological oxygen demand (BOD), chemical oxygen demand (COD), suspended solids (SS), pH value (pH) and ammoniacal nitrogen (NH3-NL). Given its scope, the book is suitable for graduate students, researchers and water quality scientists.
    Materialart: Online-Ressource
    Seiten: XII, 55 p. 18 illus., 16 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811534850
    Serie: SpringerBriefs in Water Science and Technology,
    URL: https://doi.org/10.1007/978-981-15-3485-0
    DOI: 10.1007/978-981-15-3485-0
    DDC: 363.73
    Sprache: Englisch
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  • 82
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    Online-Ressource
    Marine Oil and Gas Exploration in China (2020)
    Berlin, Heidelberg :Springer Berlin Heidelberg :
    Details
    Schlagwort(e): Geology. ; Sedimentology. ; Oceanography. ; Cogeneration of electric power and heat. ; Fossil fuels. ; Geology. ; Sedimentology. ; Ocean Sciences. ; Fossil Fuel.
    Beschreibung / Inhaltsverzeichnis: Regional tectonic setting and prototype basin evolution -- Characteristics and evolution of Lithofacies Paleogeography -- Major source rocks and distribution -- Reservoir type and origin -- Regional cap rock and hydrocarbon preservation -- Reservoir type and spatial distribution.
    Kurzfassung: This book systematically introduces the petroleum geological characteristics and exploration theory of marine strata in China. On the basis of four major basins, 14 typical cases have been studied in which 13 cases are from conventional oil and gas fields and 1 case is from shale gas field, along with their hydrocarbon generation, migration, accumulation, and distribution characteristics. The book provides a reference for geologists around the globe to understand the exploration history, methods and advances in marine strata oil and gas exploration in China.
    Materialart: Online-Ressource
    Seiten: XXII, 570 p. 322 illus., 295 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783662611470
    URL: https://doi.org/10.1007/978-3-662-61147-0
    DOI: 10.1007/978-3-662-61147-0
    DDC: 551
    Sprache: Englisch
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  • 83
    Online-Ressource
    Online-Ressource
    Suriname Revisited: Economic Potential of its Mineral Resources (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Geology. ; Mineralogy. ; Power resources. ; Geology. ; Mineralogy. ; Natural Resource and Energy Economics.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction -- Chapter 2. Geology of Suriname -- Chapter 3. A Brief History of Exploration Work -- Chapter 4. Modeling Potential: Minimal Economic Resource Parameters -- Chapter 5. Gold -- Chapter 6. Bauxite -- Chapter 7. Base metals -- Chapter 8. Other Metallic Minerals -- Chapter 9. Critical Raw Materials -- Chapter 10. Other Minerals -- Chapter 11. Looking ahead.
    Kurzfassung: This book summarizes the exploration history and provides a framework for assessing the economic potential of the country’s minerals by defining minimal deposit parameters for the various commodities present. Suriname was explored extensively for mineral occurrences in the course of the previous century, indicating the presence of a range of commodities. The country mined and processed bauxite for a century (until 2016), and has an even longer history of small-scale alluvial gold mining; it is currently home to two major gold producers. However, exploration activities have been limited during the past 4 decades as most parts of Suriname’s interior are difficult to access, making geological fieldwork both difficult and expensive. Further, the markets and prices have changed in the interim, which calls for a fresh look at the historic data. .
    Materialart: Online-Ressource
    Seiten: XV, 90 p. 33 illus., 29 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030402686
    Serie: SpringerBriefs in Earth Sciences,
    URL: https://doi.org/10.1007/978-3-030-40268-6
    DOI: 10.1007/978-3-030-40268-6
    DDC: 551
    Sprache: Englisch
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  • 84
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    Online-Ressource
    Slate as Dimension Stone : Origin, Standards, Properties, Mining and Deposits (2020)
    Cham :Springer International Publishing :
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    Schlagwort(e): Geology. ; Mineralogy. ; Conservation biology. ; Ecology . ; Geotechnical engineering. ; Geology. ; Mineralogy. ; Conservation Biology. ; Geotechnical Engineering and Applied Earth Sciences.
    Beschreibung / Inhaltsverzeichnis: 1.Slate in architecture -- 2.The origin of slate -- 3.Methodology and standards -- 4.Properties of slate -- 5.Weathering of slate -- 6.Mining of slate and production -- 7.Slate deposits.
    Kurzfassung: This book offers a comprehensive review devoted exclusively to slate as dimension stone. Beginning with a description of the slate as dimension stone, the book describes the origin of slate and related geological phenomena. It thoroughly explains key data acquisition methods and techniques, which are accompanied by extensive data. In turn, slate standards are introduced and compared with regard to their importance for product quality. The book covers in detail the specific petrographical, fabric, strength, physical properties and weathering behaviour of slates. The chapter on mining and production provides an overview of the different forms of exploitation and related geotechnical aspects, together with production and workflow design, from the beginning to the final product. The second part comprises a thorough description of worldwide slate deposits and their geology, properties and appearance as well as a brief introduction of the history. Given its scope and accessible format, the book represents an essential guide for scientists, engineers, and professionals in geology, conservation science, architecture, and mining, as well as readers who are active in the slate industry.
    Materialart: Online-Ressource
    Seiten: XI, 492 p. 305 illus., 283 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030356675
    Serie: Springer Mineralogy,
    URL: https://doi.org/10.1007/978-3-030-35667-5
    DOI: 10.1007/978-3-030-35667-5
    DDC: 551
    Sprache: Englisch
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  • 85
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    Online-Ressource
    Microbial Bioremediation & Biodegradation (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pollution. ; Environmental chemistry. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Environmental health. ; Pollution. ; Environmental Chemistry. ; Environmental Engineering/Biotechnology. ; Environmental Health.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Bioremediation Approaches for Treatment of Pulp and Paper Industry Wastewater: Recent Advances and Challenges -- Chapter 2. Microbial remediation of Heavy Metals -- Chapter 3. Dyes: Effect on the Environment and Biosphere and Their Remediation Constraints -- Chapter 4. Microbial Bioremediation and Biodegradation of Hydrocarbons, Heavy Metals, and Radioactive Wastes in Solids and Wastewaters -- Chapter 5. Advancement of Omics: Prospects for Bioremediation of Contaminated Soils -- Chapter 6. Microbial Biotransformation of Hexavalent Chromium [Cr(VI)] in Tannery Wastewater -- Chapter 7. Bioremediation: A Low-Cost and Clean-Green Technology for Environmental Management -- Chapter 8. Microbial Degradation of Pharmaceuticals and Personal Care Products from Wastewater -- Chapter 9. Extremophiles: A Powerful Choice for Bioremediation of Toxic Oxyanions -- Chapter 10. Conventional and Nonconventional Biodegradation Technologies for Agro-Industrial Liquid Waste Management -- Chapter 11. White Rot Fungi: Nature’s Scavenger -- Chapter 12. Nanobioremediation: An Emerging Approach for a Cleaner Environment -- Chapter 13. Bioelectrochemical System for Bioremediation and Energy Generation -- Chapter 14. Ligninolysis: Roles of Microbes and Their Extracellular Enzymes -- Chapter 15. Biosorption of Heavy Metals by Cyanobacteria: Potential of Live and Dead Cells in Bioremediation -- Chapter 16. Bioremediation of pharmaceuticals in water and wastewater -- Chapter 17. Bioremediation Of Saline Soil by Cyanobacteria -- Chapter 18. Advancement in Treatment Technologies of Biopharmaceutical Industrial Effluents.-Chapter 19. Marine Bacteria: A Storehouse of Novel Compounds for Biodegradation -- Chapter 20. Energy-Efficient Anaerobic Ammonia Removal: From Laboratory to Full-Scale Application -- Chapter 21. Microbial Degradation of Natural and Synthetic Rubbers.-.
    Kurzfassung: Microbial or biological degradation has long been the subject of active concern, and the rapid expansion and growing sophistication of various industries in the last century has significantly increased the volume and complexity of toxic residues of wastes. These can be remediated by plants and microbes, either natural origin or adapted for a specific purpose, in a process known as bioremediation. The interest in microbial biodegradation of pollutants has intensified in recent years in an attempt to find sustainable ways to clean contaminated environments. These bioremediation and biotransformation methods take advantage of the tremendous microbial catabolic diversity to degrade, transform or accumulate a variety of compounds, such as hydrocarbons, polychlorinated biphenyls, polaromatic hydrocarbons pharmaceutical substances, radionuclides and metals. Unlike conventional methods, bioremediation does not physically disturb the site. This book describes the basic principles of biodegradation and shows how these principles are related to bioremediation. Authored by leading, international environmental microbiologists, it discusses topics such as aerobic biodegradation, microbial degradation of pollutants, and microbial community dynamics. It provides valuable insights into how biodegration processes work and can be utilised for pollution abatement, and as such appeals to researchers and postgraduate students as well as experts in the field of bioremediation.
    Materialart: Online-Ressource
    Seiten: IX, 550 p. 69 illus., 48 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811518126
    URL: https://doi.org/10.1007/978-981-15-1812-6
    DOI: 10.1007/978-981-15-1812-6
    DDC: 363.73
    Sprache: Englisch
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  • 86
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    Online-Ressource
    The Geology of Kuwait (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Geology. ; Sedimentology. ; Paleontology . ; Geophysics. ; Geology. ; Sedimentology. ; Paleontology. ; Geophysics.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Surface Geology of Kuwait -- Chapter 2. Subsurface stratigraphy of Kuwait -- Chapter 3. Sand dunes in Kuwait, morphometric and chemical characteristics -- Chapter 4. Marine Geology of Kuwait -- Chapter 5. Structures and Tectonics of Kuwait.
    Kurzfassung: This open access book contains a set of chapters covering all aspects of geosciences related to Kuwait and adjactent regions, including Iran, Saudi Arabia and the Arab Gulf states. It covers basic information about the geology including a wide range of geoscientific disciplines such as marine geology, structural geology, hydrogeology and geophysics related to the region. This book is aimed at researchers and students, as well as professionals in the field of hazard mitigation and petroleum exploration.
    Materialart: Online-Ressource
    Seiten: XII, 242 p. 211 illus., 177 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031167270
    Serie: Regional Geology Reviews,
    URL: https://doi.org/10.1007/978-3-031-16727-0
    DOI: 10.1007/978-3-031-16727-0
    DDC: 551
    Sprache: Englisch
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  • 87
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    Online-Ressource
    Atmospheric Reactive Nitrogen in China : Emission, Deposition and Environmental Impacts (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pollution. ; Environmental health. ; Sustainability. ; Biotic communities. ; Biodiversity. ; Pollution. ; Environmental Health. ; Sustainability. ; Ecosystems. ; Biodiversity.
    Beschreibung / Inhaltsverzeichnis: Chapter 1 Overview of atmospheric reactive nitrogen in China from a global perspective -- Part I Reactive nitrogen emission and deposition in China -- Chapter 2 Anthropogenic emissions of SO2, NOx and NH3 emissions in China -- Chapter 3 Monitoring nitrogen deposition in China -- Chapter 4 Modelling nitrogen deposition in China -- Chapter 5 Reactive nitrogen budgets in China -- Part II Contribution of atmospheric reactive nitrogen to China’s air pollution -- Chapter 6 Contribution of atmospheric reactive nitrogen to haze pollution in China -- Chapter 7 Contribution of reactive nitrogen to ozone pollution in China -- Chapter 8 Contribution of atmospheric nitrogen to acid deposition in China -- Part III Impacts of nitrogen deposition on China’s ecosystems Chapter 9 Impacts of nitrogen deposition on forest ecosystems in China -- Chapter 10 Impact of nitrogen deposition on China’s grassland ecosystems -- Chapter 11 Impact of nitrogen deposition on China’s desert ecosystems -- Chapter 12 Impact of nitrogen deposition on China’s lake ecosystems: Taking Lake Dianchi as an example -- Part IV Reactive N Regulation Chapter 13 Nitrogen regulation in China’s agricultural systems -- Chapter 14 National regulation of SO2 and NOX emissions in China.
    Kurzfassung: Atmospheric reactive nitrogen (N) emissions, as an important component of global N cycle, have been significantly altered by anthropogenic activities, and consequently have had a global impact on air pollution and ecosystem services. Due to rapid agricultural, industrial, and urban development, China has been experiencing an increase in reactive N emissions and deposition since the late 1970s. Based on a literature review, this book summarizes recent research on: 1) atmospheric reactive N in China from a global perspective (Chapter 1); 2) atmospheric reactive N emissions, deposition and budget in China (Chapters 2-5); 3) the contribution of atmospheric reactive N to air pollution (e.g., haze, surface O3, and acid deposition) (Chapters 6-8); 4) the impacts of N deposition on sensitive ecosystems (e.g., forests, grasslands, deserts and lakes) (Chapters 9-12); and 5) the regulatory strategies for mitigation of atmospheric reactive N pollution from agricultural and non-agricultural sectors in China (Chapters 13-14). As such it offers graduate students, researchers, educators in agricultural, ecological and environmental sciences, and policy makers a glimpse of the environmental issues related to reactive N in China .
    Materialart: Online-Ressource
    Seiten: XVII, 331 p. 99 illus., 72 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811385148
    URL: https://doi.org/10.1007/978-981-13-8514-8
    DOI: 10.1007/978-981-13-8514-8
    DDC: 363.73
    Sprache: Englisch
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  • 88
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    Online-Ressource
    Water Availability and Management in Mexico (2020)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pollution. ; Statistics . ; Geology. ; Geographic information systems. ; Pollution. ; Statistics in Engineering, Physics, Computer Science, Chemistry and Earth Sciences. ; Geology. ; Geographical Information System.
    Beschreibung / Inhaltsverzeichnis: 1. Preface -- 2. Acknowledgment -- 3. Part I: Water Availability 1 Overview of the water condition in México -- 4. 2 Hydrological watersheads in Mexico. Division and legal definition -- 5. 3 The Groundwater condition in Mexico -- 6. 4 Runoff simulation under future climate change and uncertainty -- 7. 5 Hydraulic fracking of not conventional reservoirs in Mexico: The issue of water and waste control -- 8. Part II. Water Quality 6 Pollution in wastewater used for irrigation in the Mezquital Valley, México: case study -- 9. 7 Mining industry in Mexico: Recycling of flotation effluents to the process using anaerobic sulfate-reducing consortia in UASB reactors for the elimination dissolved metals -- 10. 8 Water body trophic state determinations. Case study Tecocomulco lagoon, Hidalgo, Mexico -- 11. 9 Water quality management for a sustainable supply. The diagnosis of the State of San Luis Potosi, Mexico -- 12. 10 The wetland of Cajititlán Lake severely deteriorated and in danger of dying out -- 13. 11 Water quality of the Nexapa River: a diagnosis -- 14. 12 Impacts on the groundwater quality that supplies the Puebla City by the effect of aquifer intensive exploitation -- 15. Part III: Water Allocation 13 Water resources allocation with supply and demand uncertainties -- 16. 14 An overview of aquaculture activity in Hidalgo state -- 17. 15 Drinking Water Services Situation by the Region in the State of Nuevo León, Mexico -- 18. 16 Population and tourism dynamics, its effects on the future demand for water. Case study from Los Cabos, Baja California Sur -- 19/ Part IV: Water Governance 17 Water governance in 16 Mexican National Parks -- 20. 18 Conflict in border condition: the dispute over the use of water in the Mexicali valley -- 21. 19 The institutional challenges of the municipalities of Zacatecas in the wastewater treatment -- 22. Part V: Water Management 20 The institutional challenges of the municipalities of Zacatecas in the wastewater treatment -- 23. 21 Improving environmental services of Candelaria River basin by restoring ecological connectivity -- 24. 22 Transdisciplinary approach to assessing socio-hydrological resilience in urban metropolitan environments: a Mexican perspective -- 25. 23 The 80% paradigm: An appointment with the sewage in Cuernavaca.
    Kurzfassung: This book presents several complex case studies related to water management and planning in the context of pollution, growing demands, and global climate change in Mexico, but which are also relevant for other countries in Latin America. These concerns are of critical importance for policymakers who are coping with multiple conflicting interests. Water availability in Mexico is polarized, with abundant rainfall and large rivers in the south, and desert-like conditions in the north. The central region, which is the most industrialized, is overpopulated. Mexico City pours millions of cubic meters of “blackwater” into the northern valley daily and receives its clean water from the south. To address these unsustainable conditions, the world's 4th biggest water treatment plant went into operation in 2018. The water infrastructure and governance must satisfy the demands of all sectors, including agricultural, urban, and economic activities. At the same time, water resources are affected by drought, and climate change puts constraints on the supply. As such, regulation and monitoring are important when it comes to adherence to agreed plans and priorities. The book is divided into four sections. 1: Water Availability discusses quantitative aspects, such as supply, methods of calculation, and fracking. 2: Water Quality highlights pollution risks and diagnosis of water resources. 3: Water Allocation examines the sectoral demands and vulnerability due to unsustainable irrigation. 4: Water Management and Governance focuses on laws, urban rules, national parks, planning, and integrated water resources management, among other topics. The chapters include illustrative case studies in Mexico, such as basins, cities, reservoirs, and aquifers, water supply demand assessment, planning, and management.
    Materialart: Online-Ressource
    Seiten: X, 516 p. 155 illus., 108 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9783030249625
    Serie: Water Science and Technology Library, 88
    URL: https://doi.org/10.1007/978-3-030-24962-5
    DOI: 10.1007/978-3-030-24962-5
    DDC: 363.73
    Sprache: Englisch
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  • 89
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    Introduction to GNSS Geodesy : Foundations of Precise Positioning Using Global Navigation Satellite Systems (2022)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Geology. ; Measurement. ; Measuring instruments. ; Geographic information systems. ; Geotechnical engineering. ; Geology. ; Measurement Science and Instrumentation. ; Geographical Information System. ; Geotechnical Engineering and Applied Earth Sciences.
    Beschreibung / Inhaltsverzeichnis: Chapter 1-Introduction -- Chapter 2-Reference systems in GNSS geodesy -- Chapter 3-Estimating geodetic parameters from GNSS -- Chapter 4-GNSS satellite tracking and observation models -- Chapter 5-Geodetic CORS and tracking networks -- Chapter 6-Satellite orbit determination -- Chapter 7-GNSS data processing and biases -- Chapter 8-GNSS software and online tools -- Chapter 9-GNSS geodetic solution exchange formats -- Chapter 10-GNSS time series combinations and data products -- Chapter 11-Geospatial applications of GNSS geodesy -- Chapter 12-Scientific applications of GNSS geodesy.
    Kurzfassung: Introduction to GNSS Geodesy is a concise reference for beginners and experts in GNSS-based satellite geodesy. It covers all of the important concepts in almost a third of the space of the other GNSS books. Th e book begins with a case study in Augmented Reality to set the stage for what is to come and then moves on to the key elements of GNSS geodesy that make accurate and precise geopositioning possible. For example, it is important to understand the geodetic reference systems and the associated GNSS data processing strategies that enable both accurate and high-precision geopositioning. Chapter 2 gives an overview of GNSS constellations and signals, highlighting important characteristics. Chapter 3 then introduces reference systems in geodesy, covering such topics as time systems, geodetic datums, coordinate systems, coordinate conversions and transformations, and International Terrestrial Reference Frame. Th is lays the framework for the rest of the book. Chapters 4 and 5 dig deep into mathematical formulation of GNSS parameter estimation and observation models. All the concepts are presented clearly and concisely, with diagrams to assist reader comprehension. Chapter 6 describes Continuously Operating Reference Station (CORS) networks and their role in geodesy and definition of reference frames. Various global and regional CORS networks are presented in this section. Th e chapter also covers GNSS data and common formats such as RINEX and RTCM. Chapter 7 introduces the whole cycle of GNSS data processing, including preprocessing, ambiguity fixing, and solution reprocessing methods as commonly used in both epoch solutions and time series data. Th e book concludes with appendices on orbit modelling, GNSS linear combinations, application examples, and an example linear model.
    Materialart: Online-Ressource
    Seiten: XV, 166 p. 43 illus., 38 illus. in color. , online resource.
    Ausgabe: 1st ed. 2022.
    ISBN: 9783030918217
    URL: https://doi.org/10.1007/978-3-030-91821-7
    DOI: 10.1007/978-3-030-91821-7
    DDC: 551
    Sprache: Englisch
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  • 90
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    Online-Ressource
    The African Marine Litter Outlook (2023)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pollution. ; Refuse and refuse disposal. ; Water. ; Hydrology. ; Africa Economic conditions. ; Oceanography. ; Sustainability. ; Pollution. ; Waste Management/Waste Technology. ; Water. ; African Economics. ; Ocean Sciences. ; Sustainability.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Introduction to Marine Litter in Africa -- Chapter 2. Marine litter sources and distribution pathways -- Chapter 3. Impacts and Threats of Marine Litter to Africa Chapter -- Chapter 4. Legal and Policy Frameworks to address marine litter through improved livelihoods -- Chapter 5. The way forward, building upon-the-ground innovation.
    Kurzfassung: This open access book provides a cross-sectoral, multi-scale assessment of marine litter in Africa with a focus on plastics. From distribution, to impacts on environmental and human health, this book looks at what is known scientifically. It includes a policy analysis of the instruments that currently exist, and what is needed to help Africa tackle marine litter—including local and transboundary sources. Across 5 chapters, experts from Africa and beyond have put together a summary of the scientific knowledge currently known about marine litter in Africa. The context of the African continent and future projections form a backdrop on which the scientific knowledge is built. This scientific knowledge incorporates quantities, distributions, and pathways of litter into the marine environment, highlighting where the impacts of marine litter are most felt in Africa. These impacts have widespread effects, with ecological, social, economic, and human health repercussions. While containing detailed scientific information, this book provides a sound knowledge base for policymakers, NGOs and the broader public.
    Materialart: Online-Ressource
    Seiten: XXII, 224 p. 33 illus., 29 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031086267
    URL: https://doi.org/10.1007/978-3-031-08626-7
    DOI: 10.1007/978-3-031-08626-7
    DDC: 363.73
    Sprache: Englisch
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  • 91
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    Structural Geology and Tectonics Field Guidebook—Volume 2 (2023)
    Cham :Springer International Publishing :
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    Schlagwort(e): Geology. ; Sedimentology. ; Paleontology . ; Petrology. ; Geology. ; Sedimentology. ; Paleontology. ; Petrology.
    Beschreibung / Inhaltsverzeichnis: Chapter 1 - Field guide for a complete cross-section of the Central Andes along main roads (Carla Cristine Porcher, Márcia Elisa Boscato Gomes, Amós Martini, Giuseppe Betino De Toni, João Pacífico Machado) -- Chapter 2 – Structures associated with the dynamics of granitic rock emplacement (NW Portugal) (Jorge Pamplona, Benedito C. Rodrigues, Mark Peternell, Alex Lorenz, Alex Schimdt, Melissa Mengert, Thomas Altmeyer, Jonas Köpping) -- Chapter 3 - Tectonically significant fault zones in Central Europe (Germany, Czech Republic and Poland) and their surface and subsurface outcrops: Franconian Line, Hronov-Porici Fault, Sudetic Marginal Fault and Lusatian Fault (Lucie Novakova) -- Chapter 4 - Geological field observations along the Pandoh Syncline:the Mandi-Kataula-Bajura section of Himachal Pradesh, NW-India (Paramjeet Singh, Pratap Chandra Sethy, Hrithik Rastogi, M. Rajanikanta Singh, A. Krishnakanta Singh, Satyajit Singh Thakur, Saurabh Singhal) -- Chapter 5 - The rock outcrops at Raghunathdi, SE of Ghatsila (Jharkhand, India): A spectacular preservation of polyphase folding (Srinanda Ganguly, Arpita Samanta, Abhik Kundu) -- Chapter 6 - Spectacular soft-sediment deformation structures in sedimentary rock outcrops of Damodar Valley Basin, West Bengal, India: A field guide (Arpita Samanta, Abhik Kundu) -- Chapter 7 - Structural geological field guide: Bhuj area (Gujarat, India) (Nidhi Lohani, Soumyajit Mukherjee, Seema Singh, Aashu Pawar, Mohamedharoon Shaikh) -- Chapter 8 - Structural and sedimentary field studies in Angul District, Odisha, India (Subhajit Sinha, Ananya Ghosh, Somnath Mishra) -- Chapter 9 - New Structural geological input from the Barmer Basin, Rajasthan (India) (Mohit Kumar Puniya, Ashish Kumar Kaushik, Soumyajit Mukherjee, Swagato Dasgupta, Nihar Ranjan Kar, Mery Biswas, Ratna Choudhary) -- Chapter 10 - Structural geology and stability issue of the Giral lignite mine, Rajasthan, India (Mohit Kumar Puniya, Ashish Kumar Kaushik, Soumyajit Mukherjee, Nihar Ranjan Kar, Mery Biswas, Ratna Choudhary) -- Chapter 11 - Relationship between deformation structures and rock mass rating: A case study of underground power house, Andhra Pradesh- India (Mohit Kumar Puniya, Sohan Kumar, Ashish Kumar Kaushik, Nikhil Puniya) -- Chapter 12 - Macrostructures mimic Meso-structures (Harsh Bhu, Ritesh Purohit, Riya Dutta) -- Chapter 13 - Review on Role of multi-constellation Global Navigation Satellite System-Reflectometry (GNSS-R) for real-time sea-level measurements (Kutubuddin Ansari) -- Chapter 14 - Architecture and structures of Kiradu temple (Barmer region, Rajasthan, India) (Paramita Haldar,, Mohit Kumar Puniya, Mery Biswas, Soumyajit Mukherjee, Nihar Ranjan Kar, Ratna Choudhary).
    Kurzfassung: This book is the second volume of an edited work aiming to help novice geologists to explore terrains independently. Geoscience fieldwork with focus on structural geology and tectonics has become more important in the last few years from both academic and industrial perspectives. This book also works as a resource material for batches of students or geological survey professionals undergoing training as parts of their course curriculum/training. Industry persons, on the other hand, can get a first-hand idea about what to expect in the field, in case no academic persons are available with the team. This book focuses on structural geology and tectonics and compiles terrains from several regions of the globe. This book also includes field guide chapters for primary sedimentary structures.
    Materialart: Online-Ressource
    Seiten: XVI, 418 p. 323 illus., 304 illus. in color. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9783031195761
    Serie: Springer Geology Field Guides, FieldGuides,
    URL: https://doi.org/10.1007/978-3-031-19576-1
    DOI: 10.1007/978-3-031-19576-1
    DDC: 551
    Sprache: Englisch
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    The Tectonics and Metallogenesis of Asia (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Geology. ; Geophysics. ; Mineralogy. ; Geology. ; Geophysics. ; Mineralogy.
    Beschreibung / Inhaltsverzeichnis: Introduction -- Tectonic Domains and Tectonic Units in Asian Continent -- The Tectonic Evolution of Asian Continental Lithosphere -- Tectono-Metallogenesis in Asian Continent.
    Kurzfassung: The purpose of this book is to provide a review of tectonic outlines of the Asian continent, metallogenesis rules of 242 large deposits or fields in 67 tectonic units of 6 tectonic domains in the Asia, and guidelines for the mining companies to effectively prospect the large deposits in the Asia in future. The main contents include the tectonic evolution of every tectonic unit in Asia at different geological periods, the mechanism of growth and intraplate deformation of the Asian continental lithosphere, the lithospheric types of the Asian continent, and relationship between tectonic evolution and mineralization process in the Asian continent. .
    Materialart: Online-Ressource
    Seiten: XI, 319 p. 201 illus., 190 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811530326
    URL: https://doi.org/10.1007/978-981-15-3032-6
    DOI: 10.1007/978-981-15-3032-6
    DDC: 551
    Sprache: Englisch
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  • 93
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    Water Resources of Pakistan : Issues and Impacts (2021)
    Cham :Springer International Publishing :
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    Schlagwort(e): Geology. ; Water. ; Hydrology. ; Geology. ; Water.
    Beschreibung / Inhaltsverzeichnis: Chapter 1 Pakistan’s Water Resources: Overview and Challenges -- Chapter 2 Pakistan’s Water Resources: From Retrospect to Prospect -- Chapter 3 Pakistan’s Transboundary Water Challenge -- Chapter 4 Water Security in Pakistan: Availability, Accessibility and Utilisation -- Chapter 5 Climate Change in the Mountains of Pakistan and its Water Availability Implications -- Chapter 6 Pakistan’s Water Resources in the Era of Climate Change -- Chapter 7 Unlocking Economic Growth Under a Changing Climate: Agricultural Water Reforms in Pakistan -- Chapter 8 Sustainability Analysis of Irrigation Water Management in Punjab -- Chapter 9 Examining Irrigated Agriculture in Pakistan with a Water-Energy-Food Nexus Approach -- Chapter 10 Groundwater Crisis: a Crisis of Governance? -- Chapter 11 Spatial Variability of Groundwater Storage in Pakistan -- Chapter 12 Impacts of Water Quality on Human Health in Pakistan -- Chapter 13 Improving Water Management in Pakistan using Social-Ecological Systems Research -- Chapter 14 A Roadmap for a Comprehensive Water Resources Forecast System for Pakistan -- Chapter 15 Ways Forward to Improve Water Security in Pakistan.
    Kurzfassung: This book presents the first comprehensive assessment of water resources in Pakistan including surface water resources and groundwater resources. It gives a detailed overview of issues and challenges related to water which have not been adequately addressed e.g. water resource vulnerability to climate change, groundwater depletion and contamination, and water governance etc. It includes a collection and compilation of unpublished and scattered data from the archives and repositories of various national institutions and organization. Given the literature dearth, this book will not only be a comprehensive assessment of water resources in Pakistan but can also can as outstanding textbook on water resource management in Pakistan. It will attract a great range of readership including water specialists, researchers, undergraduate and post graduate students and policy makers from Pakistan as well as from overseas.
    Materialart: Online-Ressource
    Seiten: XVI, 318 p. 72 illus., 68 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030656799
    Serie: World Water Resources, 9
    URL: https://doi.org/10.1007/978-3-030-65679-9
    DOI: 10.1007/978-3-030-65679-9
    DDC: 551
    Sprache: Englisch
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  • 94
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    Online-Ressource
    Groundwater in Egypt’s Deserts (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Geology. ; Sustainability. ; Energy policy. ; Energy and state. ; Geophysics. ; Geochemistry. ; Geology. ; Sustainability. ; Energy Policy, Economics and Management. ; Geophysics. ; Geochemistry.
    Beschreibung / Inhaltsverzeichnis: Overview of the Egyptian Deserts' Ground Water Resources and Their Qualities -- Fault zone hydrogeology and structural control on groundwater flow in the Egyptian aquifers -- Hydrogeology and Waterlogging problem in Egypt's Deserts, Case Study: Abu Meina Archaeological site , Burg Al-Arab -- Conceptual Models for Groundwater Management in Egypt's Deserts -- Characterizing ecosystem services to human well-being in groundwater dependent desert environments.
    Kurzfassung: This book brings together contributions from groundwater researchers and scientists on underground water resources in Egypt's deserts. The aquifers' quantity and quality are evaluated in many regions of the Egyptian deserts using established methods that can be effectively employed to investigate the potential for sustainable development in Egypt and similarly arid countries. The water resources in Egypt's deserts are subject to deterioration, mainly by land salinization and water deficiency. This book presents the best management practices, water quantity and quality, and optimal and sustainable usage of available groundwater. The book offers a unique guide for all readers interested in groundwater, modeling, and assessment for sustainable development in Egypt and countries with similar weather and water conditions. .
    Materialart: Online-Ressource
    Seiten: X, 442 p. 178 illus., 162 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030776220
    Serie: Springer Water,
    URL: https://doi.org/10.1007/978-3-030-77622-0
    DOI: 10.1007/978-3-030-77622-0
    DDC: 551
    Sprache: Englisch
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  • 95
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    Fresh Water Pollution Dynamics and Remediation (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pollution. ; Water. ; Hydrology. ; Environmental engineering. ; Biotechnology. ; Bioremediation. ; Freshwater ecology. ; Marine ecology. ; Pollution. ; Water. ; Environmental Engineering/Biotechnology. ; Freshwater and Marine Ecology.
    Beschreibung / Inhaltsverzeichnis: The Concerns for Global Sustainability of Freshwater Ecosystems -- Freshwater Pollution: Effects on Aquatic Life and Human Health -- Freshwater contamination: sources and hazards to aquatic biota -- Correlation Between Pollution Trends of Freshwater Bodies and Bacterial Disease of Fish Fauna -- Impact of Pollution on Quality of Freshwater Ecosystems -- Heavy metal intrusion and accumulation in aquatic ecosystems -- Impact of climate change on freshwater ecosystem and its sustainable management -- Role of biotools in restoration of freshwater ecosystems Bioremediation -- A Sustainable and Emerging Tool for Restoration of Polluted Aquatic Ecosystems -- Biosorption as Environmentally Friendly Technique for Heavy Metal Removal from Wastewater -- Biotechnological interventions as an aquatic clean up tool -- Analysis of hydrology, sediment retention, biogenic-calcification and -scavenging as self-remediative lacustrine functions -- Remediation of pesticides through microbial and phytoremediation techniques -- Trends in Phyto-management of Aquatic Ecosystems and Evaluation of Factors Affecting Removal of Inorganic Pollutants from Water Bodies -- Urban Pond Ecosystems: Preservation and Management Through Phytoremediation -- Aquatic Pollution Stress and Role of Biofilms as Environment Cleanup Technology -- Wonders of Nanotechnology for Remediation of Polluted Aquatic Environs.
    Kurzfassung: Freshwater is a finite resource and is being deteriorated directly and indirectly by anthropogenic pressures. Preserving the quality and availability of freshwater resources is becoming one of the most pressing environmental challenges on the international horizon. To ensure the preservation as well as availability of freshwater resources, there is a need to understand the ecology of the freshwater systems, pollution problems, their impacts, restoration techniques to be opted and the conservation measures. In this backdrop the present book on ‘Freshwater Pollution Dynamics and Remediation’ has been compiled. The book provides an understanding about the present state of art, pollution impacts including the changes in the environmental quality as well as the shift in the aquatic biological communities of the fragile freshwater ecosystems. Besides, the impact of deteriorating quality of the freshwater ecosystems on the animal and human health is also discussed in detail. This book provides a comprehensive account of the techniques based on updated research in biotechnology, bio-remediation, phyto-remediation and nano-bioremediation. The role of biosorpers and biofilms as a remediation tool has also been detailed. The book is a ready reference for researchers, scientists and educators who are involved in the freshwater pollution, remediation and management studies. The book editors with an expertise in diverse research fields in freshwater ecosystems have congregated the most inclusive research accounts on the freshwater pollution and remediation and thus developed a repository of diverse knowledge on the subject.
    Materialart: Online-Ressource
    Seiten: XV, 339 p. 49 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811382772
    URL: https://doi.org/10.1007/978-981-13-8277-2
    DOI: 10.1007/978-981-13-8277-2
    DDC: 363.73
    Sprache: Englisch
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  • 96
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    Agricultural Implications of Fukushima Nuclear Accident (IV) : After 10 Years (2023)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Pollution. ; Agriculture. ; Radiation dosimetry. ; Forestry. ; Physiology. ; Environmental monitoring. ; Pollution. ; Agriculture. ; Radiation Dosimetry and Protection . ; Forestry. ; Animal Physiology. ; Environmental Monitoring.
    Beschreibung / Inhaltsverzeichnis: 1. An Overview of our research -- 2. Recovery of Food Production from Radioactive Contamination Caused by the Fukushima Nuclear Accident -- 3. Annual Reduction of Transfer Factors of Radiocesium from Soil to Rice Cultivated in a KCl Fertilized and Straw Plowed-in Paddy Field from 2015 to 2021 -- 4. Effects of radiocesium from suspended matter and fallout on agricultural products -- 5. Verification of Uptake and Transport Properties of Cesium in Hydroponically Cultivated Quercus Serrata -- 6. Candidates for breeding target genes related to cesium transport in plants after the Fukushima Daiichi Nuclear Power Plant accident -- 7. Evaluation of the Absorption of Different Forms of Cesium from Soil -- 8. Structure, Composition, and Physicochemical Properties of Radiocesium-Bearing Microparticles Emitted by the Fukushima Daiichi Nuclear Power Plant Accident -- 9. Verification of Effects on Crops and Surrounding Environment in Agriculture Using Radioactively Contaminated Grass Silage Compost Made by Aerobic Ultra-High Temperature Fermentation -- 10. Transport of 137Cs into Fruits after External Deposition onto Japanese Persimmon Trees -- 11. Progress Towards Managing Radiocesium Contamination in Orchards -- 12. Overview of Radiocesium Dynamics in Forests: First Decade and Future Perspectives -- 13. Toward the Estimation of Radiocesium Activity Concentration in Trunks of Coppiced Quercus Serrata: Leaf Availability Instead of Felling -- 14. Decomposition of Organic Matters in a Forest Floor Enhanced Downward Migration of Radioactive Cs after the Accident of the FDNPP -- 15. Effect of exchangeable and non-exchangeable potassium in soil on cesium uptake by Quercus serrata seedlings -- 16. Ten-year Transition of Radiocesium Contamination in Wild Mushrooms in the University of Tokyo Forests after the Fukushima Accident -- 17. Challenge to resume production of mushroom bed logs by potassium fertilizer application -- 18. Studies on the revitalization of radioactive-contaminated mushroom log forests: focus on shoots -- 19. Contribution of cesium-bearing microparticles to cesium in soil and river water of the Takase River watershed and their effect on the distribution coefficient -- 20. Global Fallout: Radioactive Materials from Atmospheric Nuclear Tests That Fell Half a Century Ago and Where to Find Them -- 21. Resilience Education Program in Iitate Village for the Young Generation.
    Kurzfassung: This open access book presents the findings from on-site research into radioactive cesium contamination in various agricultural systems affected by the Fukushima Daiichi Nuclear Power Plant accident in March 2011. This fourth volume in the series reports on studies undertaken at contaminated sites such as farmland and forests, focusing on soil, water, mountain, agricultural products, and animals. It also provides additional data collected in the subsequent years to show how the radioactivity levels in agricultural products and their growing environments have changed with time and the route by which radioactive materials entered agricultural products as well as their movement between different components (e.g., soil, water, and trees) within an environmental system (e.g., forests). The book covers various topics, including radioactivity testing of food products; decontamination trials for rice and livestock production; the state of contamination in, trees, mushrooms, and timber; the dynamics of radioactivity distribution in paddy fields and upland forests; damage incurred by the forestry and fishery industries; and the change in consumers’ attitudes. In the series of this book, a real-time radioisotope imaging system has been introduced, a pioneering technique to visualize the movement of cesium in soil and in plants. This is the only book to provide systematic data on the actual change of radioactivity, which is of great value to all researchers who wish to understand the effect of radioactive fallout on agriculture. In addition, it helps the general public better understand radio-contamination issues in the environment. The project is ongoing; the research groups from the Graduate School of Agricultural and Life Sciences of The University of Tokyo continue their work in the field further to evaluate the long-term effects of the Fukushima accident.
    Materialart: Online-Ressource
    Seiten: XIII, 276 p. 1 illus. , online resource.
    Ausgabe: 1st ed. 2023.
    ISBN: 9789811993619
    URL: https://doi.org/10.1007/978-981-19-9361-9
    DOI: 10.1007/978-981-19-9361-9
    DDC: 363.73
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 97
    Online-Ressource
    Online-Ressource
    Water Resources Management of the People’s Republic of China : Framework, Reform and Implementation (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Pollution. ; Water. ; Hydrology. ; Environmental management. ; Energy policy. ; Energy and state. ; Pollution. ; Water. ; Environmental Management. ; Energy Policy, Economics and Management.
    Beschreibung / Inhaltsverzeichnis: Chapter 1. Physical settings and water challenges -- Chapter 2. Water resources management framework -- Chapter 3. Water resources management institutions -- Chapter 4. River basin management -- Chapter 5. Water resources allocation and regulation -- Chapter 6. Water rights system -- Chapter 7. Water pricing -- Chapter 8. Groundwater management -- Chapter 9 Water quality management -- Chapter 10. Recycled water use management -- Chapter 11. The strictest water resources management strategy and three redlines -- Chapter 12 River and lake leadership system -- Chapter 13. Water resources asset management -- Chapter 14. Water resources allocation and regulation in Yellow River basin -- Chapter 15. Agricultural water management in northern China -- Chapter 16 Integrated urban and rural water affair management reform: Shanghai and Beijing -- Chapter 17 -- Environmental flow definition and management: a case study of Jiaojiang River -- Chapter 18. Climate change and water resources -- Chapter 19 Conclusions and outlook.
    Kurzfassung: This book explores water resources management issues in China and possible solutions. It analyzes a wide range of general and specific topics, providing case studies and a balanced review of the past and present situation as well as future developments. The book begins with a general introduction and an overview of hydrology, water resources, and development issues in China. It then presents a management framework, including a management system, management institutions, river basin management, water pricing, water rights, and groundwater management, and discusses its implementation, covering water resources allocation and regulation in the Yellow River, integrated water affair management reforms, and agricultural water management in northern China. The last section focuses on the current reforms and hot topics, with strong emphasis on stringent water resource strategies applied to the river and lake principle system, recycled water use and water resources asset management, as well as climate change impacts, and concludes with a summary of the many changes in the water sector in China and a look at the road ahead and the areas that still need to be reformed.
    Materialart: Online-Ressource
    Seiten: XIX, 455 p. 42 illus., 30 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030619312
    Serie: Global Issues in Water Policy, 26
    URL: https://doi.org/10.1007/978-3-030-61931-2
    DOI: 10.1007/978-3-030-61931-2
    DDC: 363.73
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 98
    Online-Ressource
    Online-Ressource
    Heat-Mass Transfer and Geodynamics of the Lithosphere (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Geology. ; Thermodynamics. ; Heat engineering. ; Heat transfer. ; Mass transfer. ; Natural disasters. ; Geotechnical engineering. ; Geology. ; Engineering Thermodynamics, Heat and Mass Transfer. ; Natural Hazards. ; Geotechnical Engineering and Applied Earth Sciences.
    Beschreibung / Inhaltsverzeichnis: Preface -- The processes of heat and mass transfer in the Earth's mantle -- Thermo-gravity model for sedimentary basins -- Prospects for identifying and applied use of hydro and petrothermal energy sources in geodynamically active structures of the eastern segment of the Central Caucasus -- Models of geothermal areas: new insights from electromagnetic geothermometry -- Explosive processes in permafrost areas - new type of geocryological hazard -- Borehole temperature measurements under free thermal convection -- Geothermal regime of groundwater in Moscow under anthropogenic impact -- Geothermy of the continental margins of Eastern Russia -- Geothermal evidence of cyclic back-arc spreading in the marginal seas of the North-West Pacific -- Heat flow asymmetry on the mid-oceanic ridges of northern and southern earth hemispheres -- The correlation between Earth heat flow and oil and gas potential – fundamental pattern of Western Siberia -- Influence of hydrodynamic conditions on the mass transfer of pollutants in the areas of liquidated mines -- Factor modeling of mass transfer of pollutants in the areas of hydrogeological windows -- Hydraulic fracture problem for poroelastic medium with double porosity -- Incompletely coupled equations of hydraulic fracturing in poroelastic medium -- Geomechanical model for large scale hydraulic fracture dynamics -- Thermodynamic properties of geothermal fluids from South Russiai Kayakent and Kizlyar hot sources -- Thermodynamic properties of geothermal fluids from South Russia: Izberbash and Thernair hot sources -- ROSA Database and GIS Project: accumulation of the world largest oil and gas deposits in geological history -- Lithosphere of the West Transbaikalian sector of the Central Asian fold belt according to electromagnetic studies -- Caucasian-Arabian segment of Alpine-Himalayan convergence: an example of continental collision above mantle plume -- Geothermics and seismicity of the Caucasus region and the inverse problem of geodynamics -- Geothermics and geodynamics of the back-arc basins of the Alpine and Pacific belts -- Structure and dynamics of the lithosphere for the Eurasia-Pacific transition zone -- Recognition of Strong Earthquake–Prone Areas with a Single Learning Class Caucasus, М ≥ -- Evaluation of the influence of soils resonant properties during seismic microzoning work -- Seismotectonic model of the western margin of the South American Plate -- Permeability of the Continental Crust –Possible High Values from Laboratory Measurements and Seismological Data -- Endogenous and exogenous manifestations of geodynamic activity in the Central Caucasus.
    Kurzfassung: This volume is devoted to investigation of all aspects of heat-mass transfer processes at different scales and from various origins, as well as the formation and evolution of geological structures. These phenomena are linked to geophysical properties of rocks, geothermal resources, geothermics, fluid dynamics, stress-state of the lithosphere, deep geodynamics, plate tectonics, and seismicity, among others. The book consists of two main parts. The first concerns heat-mass transfer associated with natural and technogenic processes in the upper lithosphere. The second deals with geodynamics and seismicity. The collection of over 25 chapter from leading investigators in Russia is thus an important contribution to research on the lithosphere in connection with formation and evolution of geological structures; heat and mass transfer processes in the lithosphere and their connection with deep Earth geodynamics. Collects a range of research methodologies including application of modelling, seismic tomography, geological field works, geological-geophysical methods, and in situ measurements through instrumentation; Explains how a wide range of geological and geophysical phenomena arising in the Earth’s lithosphere can be investigated under the umbrella of a common approach to heat-mass transfer processes; Includes the latest research by more than 60 leading scientists from Russia.
    Materialart: Online-Ressource
    Seiten: X, 549 p. 205 illus., 149 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030635718
    Serie: Innovation and Discovery in Russian Science and Engineering,
    URL: https://doi.org/10.1007/978-3-030-63571-8
    DOI: 10.1007/978-3-030-63571-8
    DDC: 551
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 99
    Online-Ressource
    Online-Ressource
    Ecological Tourism in the Republic of Kazakhstan (2021)
    Cham :Springer International Publishing :
    Details
    Schlagwort(e): Geology. ; Cultural property. ; Archaeology. ; Conservation biology. ; Ecology . ; Geology. ; Heritage Management. ; Conservation Biology.
    Beschreibung / Inhaltsverzeichnis: 1. Scientific and Methodological Basis of the Ecological Tourism Development -- 2. The Natural and Recreational Potential of Kazakhstan for the Ecological Tourism Development -- 3. Social and Economic Tourism Potential of Kazakhstan -- 4. Potential Geoparks of Kazakhstan -- 5. Evaluation of Tourist-Resource Potential On Ecological Tourism At Scale Of Kazakhstan Regions -- 6. Current State and Prospects for The Ecological Tourism Development of Kazakhstan -- 7. Conclusion -- 8. References.
    Kurzfassung: This book analyses the theoretical and methodological foundations of ecotourism and geotourism and examines the essence, content, factors, and models of ecotourism development. The authors conducted research to assess the tourist and recreational potential of ecotourism in Kazakhstan. The study analyses the current state and describes the problems of the long-term development of ecotourism. Besides, the authors also show the role of specially protected natural areas in ecotourism development, including a list of organizations that can create tourist products in the environmental direction. This book also defines the primary conditions necessary for ecotourism in protected natural and rural areas. The resulting cartographic material visualizes the geospatial potential of the regions of Kazakhstan, aiming a more targeted expenditure of financial resources allocated to tourism development. Thus, the presented book is relevant from a practical perspective to scientists and researchers and is of value to business structures and stakeholders.
    Materialart: Online-Ressource
    Seiten: VIII, 281 p. 113 illus., 108 illus. in color. , online resource.
    Ausgabe: 1st ed. 2021.
    ISBN: 9783030774622
    URL: https://doi.org/10.1007/978-3-030-77462-2
    DOI: 10.1007/978-3-030-77462-2
    DDC: 551
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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  • 100
    Online-Ressource
    Online-Ressource
    Disaster Risk Communication : A Challenge from a Social Psychological Perspective (2020)
    Singapore :Springer Nature Singapore :
    Details
    Schlagwort(e): Natural disasters. ; Environmental sciences Social aspects. ; Climatology. ; Computer simulation. ; Natural Hazards. ; Environmental Social Sciences. ; Climate Sciences. ; Computer Modelling.
    Beschreibung / Inhaltsverzeichnis: Pitfall of Disaster Information: From the Perspective of Double-bind Theory -- Single-person Drill for Tsunami Evacuation and Disaster Education -- Using Computer Simulation for Effective Tsunami Risk Communication -- Gaming Approach to Disaster Risk Communication: Development and application of "Crossroad Game" -- Local Weather Information: Collaboration between Weather Forecasters and Information Users -- Disaster Education based on Legitimate Peripheral Participation Theory: A New Model of Disaster Science Communication -- Do Developed Countries Learn DRR from Developing Countries? -- Communicating Warnings in an Immanent Time Frame: Earthquake Early Warning and Short-Term Forecasting in Japan and the US.
    Kurzfassung: This book provides a unique blend of integrated disaster risk communication research conducted by authors with diverse backgrounds, including social psychology, sociology, civil engineering, informatics, and meteorology. It reports on the latest advances in collaborative and participatory action research on community-based disaster management from the frontline in Japan, Nepal, China and the USA. In addition, it employs and integrate a broad range of methodologies, including mathematical analyses, computer simulations, questionnaire surveys, gaming approaches, and participatory observation. Each chapter deals with disaster risk communication initiatives to address various hazards, such as earthquakes, tsunamis, floods and landslides, which are uniquely integrated from a social psychological perspective.
    Materialart: Online-Ressource
    Seiten: XXXV, 153 p. 35 illus., 21 illus. in color. , online resource.
    Ausgabe: 1st ed. 2020.
    ISBN: 9789811323188
    Serie: Integrated Disaster Risk Management,
    URL: https://doi.org/10.1007/978-981-13-2318-8
    DOI: 10.1007/978-981-13-2318-8
    DDC: 551
    Sprache: Englisch
    Standort Signatur Erwartet Verfügbarkeit
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