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  • Cell & Developmental Biology  (25,032)
  • Deutschland
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  • 1
    Publication Date: 2023-06-12
    Description: Soils and landscapes are bridges of space and time, as they simultaneously and authentically show essential aspects that were previously separated by time and space (such as cultural and activity-related aspects from past and present) to the trained observer - albeit only in excerpts. Therefore, this article presents a series of impact indicators for soil changes, starting with extreme (anthropogenic) interventions and ending with equally extreme ("natural") events. An essential difference to specifically planning-relevant or human ecological concepts, which, for example, specify land use/load categories, is that the following impact indicators perceive soils as a phenomenon in themselves and do not define them through attributed functions. Particular attention is focused on their changeability and vital development potential, as well as on their property as a sphere of penetration of living and material things, with emphasis on the noetic effect. The intervention or event spaces on the earth's surface can be differentiated quantitatively through the type, strength, and duration of the phenomena. The intensity of all processes can be described by amplitude (the strength of the interventions/events) and frequency (the repetition rate of the interventions/events) and can be specifically identified and quantified by, for example, material inputs or outputs per unit of time. For the first time, there would be a system for measuring the ecological quality of anthropogenic land use, which could serve as an "alert system for the external technological culture," and could help us become aware of our "inner" culture.
    Description: research
    Keywords: ddc:550 ; Boden ; Landschaft ; Bodendegeneration ; Deutschland ; Anthropogene Bodenveränderung
    Language: German
    Type: doc-type:article
    Format: 9
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  • 2
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    Deutsche Geophysikalische Gesellschaft, Hamburg
    In:  Herausgeberexemplar
    Publication Date: 2021-08-07
    Description: Die Jubiläumsschrift zum 75jährigen Bestehen der Deutschen Geophysikalischen Gesellschaft (DGG) enthält zahlreiche Beiträge von Mitgliedern zu vier Schwerpunkten: 1) Eine Aktualisierung der Geschichte der DGG vor allem zu den an Ereignissen reichen letzten 25 Jahren sowie Ergänzungen zu vorausgegangenen Darstellungen. 2) Die Darstellung der Geschichte geophysikalischer Institute und Institutionen in Deutschland inklusive eines Rückblicks auf das erfolgreiche Wirken ihrer verdienstvollen Persönlichkeiten. 3) Die Beschreibung einer Auswahl in der deutschen Geophysik angegangener Großprojekte der letzten 25 Jahre. 4) In Anlehnung an die Festschrift zum 50jährigen Gründungsjubiläum ist schließlich noch ein Kapitel zu geophysikalischen 'Detailthemen' ausgeführt. In ihm sind auch Beiträge enthalten, die Traditionslinien bzw. Arbeiten betreffen, die in der früheren DDR aufgenommen worden waren und z.T. keine direkte Fortsetzung an einer Nachfolgeinstitution gefunden haben.
    Description: commemorativepublication
    Keywords: 550 ; Geschichte der Geophysik ; Festschriften {Geophysik} ; Deutsche Geophysikalische Gesellschaft ; Deutschland ; Geophysik ; Geschichte ; FID-GEO-DE-7
    Language: German
    Type: anthology_digi
    Format: 226 S.
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  • 3
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    DGG, [Münster]
    In:  Herausgeberexemplar
    Publication Date: 2021-05-06
    Description: Wird heute genug für die wissenschaftliche und technologische Steuerung des sich immer rasanter vollziehenden globalen und regionalen Wandels der Bio- und Geosphäre getan? Hat die internationale Gemeinschaft die Kraft zu einem sinnvollen, übergreifenden "Umwelt-Management"? Geophysik kann auf Grund ihrer interdisziplinären Stellung innerhalb der Naturwissenschaften und mit ihren vielfältigen Beziehungen zur Technik zum effizienten Einsatz der Kräfte und Mittel beitragen - in einer Zeit weltweiter sozialer, politischer und eben auch ökologischer Konflikte. Geophysik kann notwendige Prioritäten wissenschaftlich begründen und verfechten und somit helfen, weittragende und konsensfähige Entscheidungen vorzubereiten, um gesellschaftliche Akzeptanz und Unterstützung für die Politik zu erreichen. Die Deutsche Geophysikalische Gesellschaft - getragen von ihrer Verantwortung um den Beitrag der Geophysik für die gemeinsame Zukunft - wendet sich im 75. Jahr ihres Bestehens mit dieser Denkschrift an die Öffentlichkeit. Teil I enthält einen Überblick zur Spezifik, zur Stellung, zu den Zielen und zur Bedeutung der Geophysik. Im Teil II stellen führende Geophysiker ausgewählte Beispiele moderner geophysikalischer Forschung vor. Teil III ist statistisch angelegt und gibt einen kurzen Überblick zu den in Deutschland angesiedelten Institutionen geophysikalischer Lehre und Forschung. Die Denkschrift "Mit Geophysik in die Zukunft" will Politiker, Industrielle, Wissenschaftler, Vertreter der Medien und interessierte Bürger erreichen, um im Interesse des Gemeinwohls zu angemessener Wissenschaftsförderung und kluger Zukunftsgestaltung beizutragen.
    Description: commemorativepublication
    Description: DFG, SUB Göttingen
    Keywords: 550 ; Wissenschaftsorganisation und -pflege {Geophysik} ; Geophysik ; Wissenschaft ; Forschung ; Deutschland ; FID-GEO-DE-7
    Language: German
    Type: anthology_digi
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  • 4
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    In:  fiz-fischerei@vti.bund.de | http://aquaticcommons.org/id/eprint/3141 | 1240 | 2012-11-10 14:05:04 | 3141 | Bundesforschungsanstalt für Fischerei
    Publication Date: 2021-06-25
    Description: Johann Heinrich von Thünen-Institute, Federal Research Institute for Rural Areas, Forestry and Fisheries began publishing the Informationen aus der Fischereiforschung = Information on Fishery Research in 2010.
    Keywords: Fisheries ; Information Management ; Gesamtproduktion 2000 ; Fischerei ; Deutschland ; Aquakulturproduktion 2000 ; Meeresfang
    Repository Name: AquaDocs
    Type: article , FALSE
    Format: application/pdf
    Format: application/pdf
    Format: 28-30
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  • 5
    Unknown
    Koblenz : Bundesanstalt für Gewässerkunde (BfG)
    Keywords: Germany ; hydrology ; Deutschland ; Hydrologie ; Atlas
    Description / Table of Contents: Der Atlas liefert kartographische Übersichten zu gewässerkundlichen Grunddaten sowie zu den Themenbereichen Hydrometeorologie, oberirdische Gewässer, Bodenwasser, Grundwasser, Wasserhaushalt und dem Themenkomplex Hydrologie-Ökologie-Mensch.
    Language: German
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  • 6
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    Inst. f. Physische Geographie, FU, Berlin
    In:  Herausgeberexemplar (FU Berlin) | ZB 20559:47
    Publication Date: 2021-03-29
    Description: Inhaltsverzeichnis : EHLERS, J. & MENSCHING, H.: Küstenversatz und Prielverlagerungen an der Nordseeküste. S. 9-22 ; FRÄNZLE, O.: Periglaziäre Formung der Altmoränengebiete Schleswig-Holsteins. S. 23-35 ; HEMPEL, L.: Rezente und fossile Mesoformen der Abtragung und Aufschüttung in Ausräumen von Schichtkammlandschaften im Teutoburger Wald. S. 37-47 ; LEHMEIER, F.: Zum Formenschatz der Schichtkammlandschaft im Niedersächsischen Bergland. S. 49-61 ; GARLEFF, K., BRUNOTTE, E. & STINGL, H.: Fußflächen im zentralen Teil der Hessischen Senke. S. 63-76 ; MÖLLER, K.: Das Eschweger Becken und seine Randbereiche — Ergebnisse geomorphographischer und hydrochemischer Analysen. S. 77-92 ; GLATTHAAR, D.: Vertikalbewegungen und ihre Bedeutung für die Formenentwicklung im Westerwald. S. 93-106 ; MÜLLER, M.J.: Periglaziärfluviale, solifluidale und abluale Formung im westlichen Hunsrück und am Ostrand der Trier-Bitburger Mulde. S. 107-118 ; BARSCH, D. & MÄUSBACHER, R.: Zur fluvialen Dynamik beim Aufbau des Neckarschwemmfächers. S. 119-128 ; LESER, H.: Schichtstufen und Talrandstufen in Südwestdeutschland. S. 129-147 ; FARRENKOPF, D.: Relief und Wasserhaushalt im Eyachtal, Nordschwarzwald. S. 149-154 ; LESER, H. & METZ, B.: Vergletscherungen im Hochschwarzwald. S. 155-175 ; HABBE, K.A.: Was kann eine geomorphologische Vollkartierung für die Stratigraphie des Quartärs leisten? S. 177-196 ; RATHJENS, C.: Jungglaziale Formung und spätglazialer Eisabbau im Chiemgau. S. 197-205 ; FISCHER, K.: Die würmzeitliche und stadiale Vergletscherung der Berchtesgadener Alpen. S. 207-225 ;
    Description: research
    Description: DFG, SUB Göttingen
    Keywords: 910.02 ; Deutschland ; Geologie ; Geomorphologie ; Glazial ; Gletscher ; Küste ; FID-GEO-DE-7
    Language: German
    Type: anthology_digi
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  • 7
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    Im Selbstverlag des Institutes für Physische Geographie der Freien Universität Berlin
    In:  Herausgeberexemplar (FU Berlin) | FB 23640:2
    Publication Date: 2021-03-29
    Description: Zur Vereinfachung wird die Vielfalt der Karstformenbezeichnungen bereinigt. Erdfall wird als Form, die in nicht verkarstungsfähigen Serien liegt, aber auf Tiefensubrosion zurückgeht, der Doline, einer Form, die in verkarstungsfähigem Material liegt, gegenübergestellt. Als Grundlage der Arbeit wurde eine detaillierte Kartierung der Auslaugungsformen durchgeführt. Hinsichtlich rezenter Subrosion erwies es sich als notwendig, die in Oberflächenwässern und wasserwirtschaftlich erfaßten Wässern gelösten Bestandteile von Chlorid, Sulfat und Karbonat zu ermitteln. Die Auswertung der gewonnenen Daten zeigt, daß ein Zusammenhang mit Gebieten besteht, die durch aktuelle Erdfälle und Dolineneinbrüche gekennzeichnet sind. Als Voraussetzung zur Reliefgenese gilt, daß das Gebiet des Unterwerra-Sattels entscheidend durch die saxonische Gebirgsbildung an der Wende Jura/Kreide und die nachfolgende klimageomorphologische Entwicklung geprägt ist. Anhand der geomorphographischen Analyse wird der Einfluß der Salz-, aber auch der Sulfatauslaugung auf die Landschaftsgenese belegt. Die Auslaugung des Salzes (Nal), dessen Mächtigkeit im Untersuchungsgebiet mit mindestens 120 m angenommen wird, und der unterlagernden ca. 130 m nächtigen Zechsteingipse (A 1 - A 3) zerrüttet die überlagernden triassischen Schichten weiter. Darüber hinaus wirkt die Subrosion von mehr als 30 m Rötgipsen und 50 m Gipsen des Mittleren Muschelkalkes im Hangenden des Zechsteins reliefformend. Die ermittelten Ergebnisse - rezente und subrezente Formen, Lösungswerte – werden zunächst in kleineren Gebietseinheiten analysiert. Die Ergebnisse der Nasseranalysen bestätigen das geomorphographische Ergebnis, so daß in Anlehnung an die Gipshorizonte von Stockwerkssubrosion gesprochen werden kann. Entscheidend geprägt ist die heutige Situation jedoch durch vorangegangene Zechsteinsalzauslaugung im tieferen Untergrund. Diese hat in den Hangendserien die Wasserwegsamkeit verstärkt, so daß die nachfolgende Sulfatsubrosion den Kleinformenschatz vor der Schichtstufe des Mittleren Buntsandsteins steuern konnte. Aufgrund ihrer für Auslaugungsgebiete typischen Ausprägung wird die Lage der Schichtstufe in weiten Teilen des Untersuchungsgebietes an das in Auslaugung befindliche Salz geknüpft. Das Auftreten von Subrosionsformen vor der Landstufe des Kaufunger Waldes, den östlichen Meißnerhängen, dem Anstieg des Schlierbachswaldes sowie vor dem Anstieg des Buntsandsteins zwischen Heldra, Frieda und Bad Sooden-Allendorf untermauert diese Interpretation. In der südlichen und südöstlichen Umrahmung des Untersuchungsgebietes wird der Salzhang aufgrund geomorphographischer Kriterien unter dem Steilanstieg des Unteren Muschelkalkes ausgewiesen. Aufgrund dieser Befunde wird die primäre Salzverbreitung als über den Unterwerra-Sattel reichend angenommen, womit sich, abgesehen von den Einflüssen der saxonischen Tektonik, alle Reliefentwicklungsprozesse allein durch Auslaugung und folgende geomorphologische Überprägung erklären lassen. Darüber hinaus ist dieses Gebiet in Nordhessen nicht nur durch eine über alle Schichten hinweggreifende Rumpfflächenbildung gekennzeichnet, sondern die Resistenzunterschiede wurden - unabhängig vom Klima - beständig herausgearbeitet. Aus diesen Ergebnissen wurde ein übergeordnetes Modell zur Reliefentwicklung erstellt. Danach existieren im Untersuchungsgebiet fünf Reliefgenerationen, wobei die postsaxonische Reliefentwicklung mit zerstörtem, die Auslaugung begünstigendem Hangendverband nach der Landhebung bzw. dem Einbruch der das Gebiet begrenzenden Grabenstrukturen, die bis ins Alttertiär reicht, nicht erfaßt werden konnte. [...]
    Description: research
    Description: DFG, SUB Göttingen
    Keywords: 910.02 ; Hessisch-thüringisches Bergland {Geologie} ; Morphogenese einzelner Regionen {Geomorphologie} ; Deutschland ; Hessen ; FID-GEO-DE-7
    Language: German
    Type: monograph_digi
    Format: 196
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  • 8
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    Im Selbstverlag des Institutes für Physische Geographie der Freien Universität Berlin
    In:  Herausgeberexemplar (FU Berlin) | ZB 20559:60
    Publication Date: 2021-03-29
    Description: In der vorliegenden Arbeit wurden Ergebnisse hydrologischer und stratigraphischer Studien zur Entwicklungsgeschichte von Brandenburger Kesselmooren vorgestellt. Für die Erfassung der aktuellen und historischen biotischen und abiotischen Standortfaktoren wurden verschiedene Methoden angewandt: floristische und vegetationskundliche Untersuchungen sowie hydrologische, hydrochemische, geochemische, geophysikalische und sedimentologische Untersuchungen und Makrorest-‚ Mikrorest- und Pollenanalyse. Der zeitlichen Einordnung der entwicklungsgeschichtlichen Prozesse dienten Radiocarbondatierungen und die pollenanalytischen Untersuchungen. Ziel der Arbeit war es, Entwicklungsstadien auszuscheiden, die von den untersuchten Mooren seit ihrer Entstehung durchlaufen wurden. Aufgrund der stratigraphischen Untersuchungen wurden Aussagen zur Beckengenese und zu den einzelnen See- und Moorentwicklungsphasen getroffen, zum Verlandungsvorgang, zu Moorbildungsbedingungen und Sukzessionsstadien. Den Entwicklungsstadien konnten über geochemische und -physikalische Untersuchungen abiotische Standortfaktoren zugeordnet werden. Die aktuellen Standortveränderungen wurden erfaßt und die vorgenommenen Erhaltungs- und Wiedervernässungsmaßnahmen dokumentiert und bewertet.
    Description: research
    Description: DFG, SUB Göttingen
    Keywords: 553.21 ; Teilfragen zu Brandenburg {Geographie} ; Moorkunde {Geomorphologie} ; Ostdeutschland, Berlin, Brandenburg {Hydrologie} ; Moorkunde {Geologie} ; Brandenburg ; Kessel-Moor ; Stratigraphie ; Hydrologie ; Geschichte ; Hochschulschrift ; Deutschland ; C/N ; Moor ; Pollen ; FID-GEO-DE-7
    Language: German
    Type: monograph_digi
    Format: 159
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  • 9
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    Friedr. Vieweg & Sohn, Braunschweig
    In:  SUB Göttingen | 8 GEOGR PHYS 203:10
    Publication Date: 2021-03-29
    Description: Dieser Band enthält 63 Artikel zu Themengebieten der Physik der festen Erde, zu magnetischen und elektrischen Feldern der Erde, zu der Physik der Atmophäre und der angewandten Geophysik veröffentlicht durch die Deutsche Geophysikalische Gesellschaft in dem Jahr 1934.
    Description: 〈html〉 〈body〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0004.pdf"〉Titelseite〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0005.pdf"〉Autorenverzeichnis〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0006.pdf"〉Sachverzeichnis〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0007.pdf"〉Karl Mack †〈/a〉〈br〉(Hiller, W.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0008.pdf"〉Die südalbanischen Erdbeben 1930/31〈/a〉〈br〉(Nowack, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0009.pdf"〉Seismische Untersuchungen des Geophysikalischen Instituts in Göttingen〈/a〉〈br〉(Gräfe, H., v. zur Mühlen, W., Müller, H. K.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0017.pdf"〉Horizontalsicht bei örtlich veränderlicher Trübung und Beleuchtung〈/a〉〈br〉(Steinhäusser, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0018.pdf"〉Referate und Mitteilungen〈/a〉〈br〉(Haase, H., Köhler, R., Berroth, A.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0019.pdf"〉Beitrag zur Berechnung von Minimum-Stabpendeln〈/a〉〈br〉(Graf, A.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0020.pdf"〉Zur Theorie elastischer Pendel mit besonderer Berücksichtigung des Holweck-Lejayschen Stabpendels〈/a〉〈br〉(Graf, A.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0021.pdf"〉Eine neue Methode für sehr präzise magnetische Messungen〈/a〉〈br〉(Koulomzine, T., Bondaletoff, N.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0022.pdf"〉Zur Frage der mit dem temperaturkompensierten Magnetsystem erreichbaren Meßgenauigkeit〈/a〉〈br〉(Kohl, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0023.pdf"〉Die Höhenverteilung der Erd-, Luft- und Höhenstrahlung〈/a〉〈br〉(Suckstorff, G. A.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0024.pdf"〉Erdstrahlungsmessungen in Bad Nauheim nach der Gammastrahlenmethode〈/a〉〈br〉(Masuch, V.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0025.pdf"〉Referate〈/a〉〈br〉(Jung, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0026.pdf"〉Abschnitt〈/a〉〈br〉(Angenheister, G., Kohlschütter, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0027.pdf"〉Hergesell geb. 29. Mai 1859〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0028.pdf"〉Hecker geb. 21. Mai 1864〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0029.pdf"〉Sprengungen zur Forschungszwecken mit Unterstützung der Notgemeinschaft der Deutschen〈/a〉〈br〉(Duckert, P.)〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0037.pdf"〉Beiträge zu den Luftschallmessungen〈/a〉〈br〉(Meißer, O., Martin, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0039.pdf"〉Seismische Untersuchungen des Geophysikalischen Instituts in Göttingen〈/a〉〈br〉(Regula, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0042.pdf"〉Berechnung der Laufzeitkurven des anormalen Schalles für windstille Atmosphäre und Vergleich mit der Laufzeitkurve der Oldebroek-Sprengung vom 15. Dezember 1932〈/a〉〈br〉(Jung, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0043.pdf"〉Ergebisse der Registrierungen von Schallwellen an kreisförmig um den Sprengherd angeordneten Stationen〈/a〉〈br〉(Duckert, P.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0044.pdf"〉Beobachtungsergebnisse über den Einfluß der "akustischen Umkehrschicht" auf die Schallausbreitung〈/a〉〈br〉(Sandmann, B.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0045.pdf"〉Zur Frage der anomalen Schallausbreitung〈/a〉〈br〉(Kölzer, J.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0046.pdf"〉Schalluntersuchungen im Polargebiet〈/a〉〈br〉(Wölcken, K.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0049.pdf"〉Betrachtungen über ebene Pendel〈/a〉〈br〉(Hahnkamm, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0051.pdf"〉Außenraum und Innenraum (Schlichtung des Streites um die Schwerkraftreduktion)〈/a〉〈br〉(Schwinner, R.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0052.pdf"〉Bemerkungen zu den Geoiden von Ackerl und Hirvonen〈/a〉〈br〉(Ledersteger, K.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0053.pdf"〉Auto-Radio als Hilfsmittel geologischer Kartierung〈/a〉〈br〉(Cloos, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0054.pdf"〉Zur photographischen Registrierung von Stationsseismometern〈/a〉〈br〉(Meißer, O.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0056.pdf"〉Ein Horizontalseismometer für die Aufzeichnung von starken Orts- und Nahbeben〈/a〉〈br〉(Critikos, N. A.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0059.pdf"〉Die Bedeutung der Unstetigkeiten im Verlauf der Schallgeschwindigkeit mit der Höhe für die normale und anomale〈/a〉〈br〉(Sandmann, B.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0060.pdf"〉Referate und Mitteilungen〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0061.pdf"〉Die Relativität der Undulationen〈/a〉〈br〉(Hopfner, F.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0062.pdf"〉Ein detonierendes Meteor über dem Weserbergland am 2. Januar 1934〈/a〉〈br〉(Hartmann, W.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0063.pdf"〉Der Meteorfall bei Stadt Rehburg am 2. Januar 1934〈/a〉〈br〉(Trommsdorff, W.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0064.pdf"〉Vergleich zwischen der Intensität der kosmischen Ultrastrahlung über Grönland und über Deutschland〈/a〉〈br〉(Wölcken, K.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0065.pdf"〉Das Grundeis〈/a〉〈br〉(Jakuschoff, P.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0066.pdf"〉Le problème des microséismes et le déferlement des vagues〈/a〉〈br〉(Gherzi, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0067.pdf"〉Note on the Hayford-Bowie tables for calculation 〈i〉g〈/i〉〈/a〉〈br〉(Bullard, E. C.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0068.pdf"〉Kann die Laplacesche Differentialgleichung für das Schwerkraftpotential auch innerhalb der Erdkruste als erfüllt angesehen werden?〈/a〉〈br〉(Grabowski, L.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0069.pdf"〉Vorträge, gehalten auf der XI. Tagung der Deutschen Geophysikalischen Gesellschaft, am 13. bis 15. September 1934 in Pyrmont〈/a〉〈br〉(Jung, K.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0072.pdf"〉Der geophysikalische Nachweis des Zechsteindolomits〈/a〉〈br〉(Müller, M.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0073.pdf"〉Berichtigung〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0074.pdf"〉Vorträge, gehalten auf der XI. Tagung der Deutschen Geophysikalischen Gesellschaft, am 13. bis 15. September 1934 in Pyrmont〈/a〉〈br〉(von Seidlitz, W., Sieberg, A., Linke, F., Gerlach, W.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0079.pdf"〉Zur Frage der Geländekorrektion bei Drehwaagemessungen〈/a〉〈br〉(Tuchel, G.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0080.pdf"〉Emanation in Boden- und Freiluft〈/a〉〈br〉(Israël, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0081.pdf"〉Die Energie der Heliokathodenstrahlen in ihrer Beziehung zur fortschreitenden Bewegung der Elektronen in den Polarlichtstrahlen〈/a〉〈br〉(Rudolph, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0082.pdf"〉Weitere Untersuchungen mit dem Sanford-Elektrometer〈/a〉〈br〉(Stoppel, R.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0083.pdf"〉Das Strömungssystem der Luft über Mogadischu〈/a〉〈br〉(Bossolasco, M.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0084.pdf"〉Messungen mit transportablen statischen Schweremessern〈/a〉〈br〉(Schleusener, A.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0086.pdf"〉Über den Energietransport bei der Sprengseismik〈/a〉〈br〉(v. Schmidt, O.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0087.pdf"〉Formen der Bodenschwingung bei sinusförmiger Anregung〈/a〉〈br〉(Köhler, R.)〈/li〉 〈li〉〈a href=" https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0088.pdf"〉Die Ausbreitungsgeschwindigkeit sinusförmiger elastischer Wellen im Boden〈/a〉〈br〉(Ramspeck, A.)〈/li〉 〈li〉〈a href=" https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0089.pdf"〉Referate und Mitteilungen〈/a〉〈br〉(Haase, H.)〈/li〉 〈li〉〈a href=" https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0090.pdf"〉Bericht über die elfte Tagung der Deutschen Geophysikalischen Gesellschaft vom 13. bis 15. September 1934 in Bad Pyrmont〈/a〉〈br〉(Jung, K.)〈/li〉 〈li〉〈a href=" https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0091.pdf"〉Berichtigung〈/a〉〈/li〉 〈li〉〈a href=" https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0092.pdf"〉Geophysikalische Berichte〈/a〉〈/li〉 〈li〉〈a href=" https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0093.pdf.pdf"〉Register der Geophysikalischen Berichte〈/a〉〈/li〉 〈li〉〈a href=" https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0010/LOG_0094.pdf"〉Mitgliederverzeichnis der Deutschen Geophysikalischen Gesellschaft nach dem Stande vom 1. Dezember 1934〈/a〉〈/li〉 〈/body〉 〈/html〉
    Description: research
    Description: DGG, DFG, SUB Göttingen
    Keywords: 550 ; Geophysik ; Geomagnetismus ; Magnetismus ; Seismik ; Atmosphäre ; Gravitation ; Wellen ; Ionosphäre ; Strahlung ; Radioaktivität ; Erdbeben ; Waves ; Deformation ; Pendel ; Boden ; Deutschland ; Grönland ; FID-GEO-DE-7
    Language: German , English , French
    Type: anthology_digi
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  • 10
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    Jena G. Neuenhahn, G.m.b.H., Universitäts-Buchdruckerei
    In:  SUB Göttingen | 8 MIN III, 8552:3
    Publication Date: 2021-07-16
    Description: Deutschlands Erdbebentätigkeit pflegt unterschätzt zu werden, weil sie gewöhnlich so harmlos erscheint. Zwar bringt der Jahresverlauf nur wenige Beben, abgesehen von gelegentlichen Schwärmen mit vielen hunderten von Einzelstößen, wie sie besonders dem Vogtland eigentümlich sind. Zudem handelt es sich dabei vorwiegend um schadlose Erderschütterungen, die kaum Beobachtung finden. Aber der Fachmann kennt daneben auch bis in die neueste Zeit hinein Erdbeben mit erheblichen Schäden und selbst Zerstörungen, die für längere Zeit das öffentliche Leben völlig beherrscht haben; mitunter wurde fast Großbebencharakter erreicht.
    Description: research
    Description: DFG, SUB Göttingen
    Keywords: 551.2 ; Seismologie {Geophysik} ; Wissenschaftsorganisation und -pflege {Geophysik} ; Erdbeben ; Seismologie ; Deutschland ; Schwarmbeben ; FID-GEO-DE-7
    Language: German
    Type: monograph_digi
    Format: 12
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  • 11
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    Akad. Verl.-Ges., Leipzig
    In:  SUB Göttingenr | 8 MIN III, 8549:23
    Publication Date: 2021-03-29
    Description: Die nachstehenden neueren Untersuchungen auf verschiedenen Gebieten geophysikalischer Forschung, die von Mitgliedern der Reichsanstalt für Erdbebenforschung in Jena durchgeführt sind, wurden erstmalig in der Festschrift zum 70. Geburtstage des früheren Direktors der Reichsanstalt, Herrn Geheimrat Professor Dr. Oskar Hecker (Beitrage zur Angewandten Geophysik, Band 4, Heft 3, Leipzig 1934) veröffentlicht. Sämtliche Arbeiten, ausgenommen diejenigen von Krumbach, gehören zu den von der Notgemeinschaft der Deutschen Wissenschaft unterstützten geophysikalischen Forschungen. A. Sieberg
    Description: research
    Description: DFG, SUB Göttingen
    Keywords: 551.22 ; Geophysik ; Seismologie {Geophysik} ; Deutschland ; Seismik ; Pendel ; Schweremessung ; Erdbeben ; FID-GEO-DE-7
    Language: German
    Type: anthology_digi
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  • 12
    Publication Date: 2021-03-29
    Description: Am Beispiel des "Leegmoores" im Timpemoor - einem ehemaligen "Heidemoor" - wurde auf Grund von boden- und moorkundlichen Untersuchungen sowie von landeskundlich-historischen Recherchen die Entwicklung der Heidemoore überprüft. Dazu wurden erstmalig die flächenhaften Verluste an Moorsubstanz durch - wiederholte Moorbrandkultur, - Entnahme von Heidesoden (Abplaggen) und - Winderosion qualitativ und quantitativ erfaßt, dazu die Moorsackung errechnet. Aus den vorhandenen moorkundlichen Fakten konnte das natürliche Moorrelief des Timpemoores rekonstruiert werden. Die Autoren weisen nach, daß die von JONAS (1934, 1935) beschriebenen Heidemoore "durch den Menschen beeinflußte Moore" darstellen. Das untersuchte Timpemoor hat sich danach im Verlauf mehrerer Jahrhunderte aus einem natürlichen gewölbten Hochmoor gebildet.
    Description: On the basis of pedological, peatland and historical investigations the origin of raised bogs with heather vegetation ("Heidemoore")was examined at the example "Leegmoor", a part of the "Timpemoor". In addition to that for the first time the loss of peat substance by - burnt-over peatland cultivation, - cutaway heather sods, - erosion by wind and - bog subsidence was calculated. With the available peatland facts it was possible to reconstruct the natural bog relief. The authors are able to demonstrate that the "Heidemoore" described by JONAS (1934, 1935) are bogs influenced by man. During the last centuries the Timpemoor developed from a natural raised bog (with convex centre) to a raised bog with heather vegetation.
    Description: research
    Description: DFG, SUB Göttingen
    Keywords: 553.21 ; bog ; Deutschland ; Germany ; Hochmoor ; land-use ; mire ; Moor ; Niedersachsen ; palaeoenvironment ; peat mining ; peatland ; Torfabbau ; FID-GEO-DE-7
    Language: German
    Type: article_digi
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  • 13
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    Reimer, Berlin
    In:  Herausgeberexemplar (FU Berlin) | 4 Z GEOGR 107:3
    Publication Date: 2021-03-29
    Description: Vergleichende Darstellung und Analyse der Arbeitsvorgänge in den Agrarlandschaften der Erde. Dieser Aufgabe unterzieht sich in einem ersten Schritt die vorliegende Studie. Sie strebt an, mit der Darstellung und Analyse des jährlichen Arbeitsvorganges die bisher wenig berücksichtigte dynamische Seite der Agrarlandschaft – ihre Rhythmik nämlich – in exakter Weise erfassen zu können. Im Vordergrund steht zunächst weniger die regionale als vielmehr die sachliche Erörterung, auf der Beispielsgrundlage jedoch einer regionalen Kontrastierung innerhalb Deutschlands bzw. aus naheliegenden Gründen der Bundesrepublik Deutschland. Späteren großräumigen Untersuchungen erst kann es vorbehalten sein, von der hier geschaffenen Plattform aus auf eine speziell regionale Betrachtungsweise überzugehen.
    Description: research
    Description: DFG, SUB Göttingen
    Keywords: 910 ; Kulturgeographie der Bundesrepublik Deutschland ; Agrar- und Forstgeographie {Wirtschaftsgeographie} ; Agrarlandschaft ; Arbeitsvorgang ; Deutschland ; FID-GEO-DE-7
    Language: German
    Type: monograph_digi
    Format: 129
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  • 14
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    Gustav Fischer Verlag Jena
    In:  SUB Göttingen | 8 MIN III, 8549:12
    Publication Date: 2021-03-29
    Description: An der Hand von Erdbeben, die im Boden Deutschlands entstanden sind, sollen folgende Fragen untersucht werden: 1) Die Wirkungsweise der einzelnen Bebenherde, von denen anzunehmen ist, dass sie verschiedenartige Charaktereigenschaften haben. Hierfür ist es notwendig, festzustellen einmal Lage und geometrisches Bild des Herdes als geologische Störungsstelle, andererseits den das Erdbeben auslösenden Bewegungsvorgang in der Herdstörung. 2) Die Abhängigkeit der scheinbaren Bebenstarken innerhalb des Schüttergebietes von Bodenbeschaffenheit und Tektonik.
    Description: research
    Description: DFG, SUB Göttingen
    Keywords: 551.22 ; Europa {Seismologie} ; Deutschland {Geophysik} ; Erdbeben ; Deutschland ; Tektonik ; geol ; FID-GEO-DE-7
    Language: German
    Type: monograph_digi
    Format: 44
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  • 15
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    Friedr. Vieweg & Sohn, Braunschweig
    In:  SUB Göttingen | 8 GEOGR PHYS 203
    Publication Date: 2021-03-29
    Description: Dieser Band enthält 72 Beiträge zu Themengebieten der Physik der festen Erde, des magnetischen und elektrischen Felds der Erde, der Physik der Atmosphäre sowie der Angewandten Geophysik, veröffentlicht durch die Deutsche Geophysikalische Gesellschaft in den Jahren 1928.
    Description: 〈html〉 〈body〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0004.pdf"〉Titelseite〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0005.pdf"〉Gezeitenerscheinungen in der Atmosphäre〈/a〉〈br〉(Bartels, J.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0006.pdf"〉Erdmagnetische Säkularvariation und die Orientation alter Kultbauwerke〈/a〉〈br〉(Wehner, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0007.pdf"〉Über die Tiefenwirkung bei geoelektrischen Potentiallinienmethoden〈/a〉〈br〉(Hummel, J. N.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0008.pdf"〉Überblick über den Gang der magnetischen Vermessung der Ostsee〈/a〉〈br〉(v. Gernet, A.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0009.pdf"〉Die Wirkung der Kontinente und Ozeane auf die Differenz 〈i〉B – A〈/i〉 der Hauptträgheitsmomente der Erde im Äquator〈/a〉〈br〉(Gutenberg, B.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0011.pdf"〉Bemerkungen zu H. v. Iherings Kritik der Theorien der Kontinentverschiebungen und der Polwanderungen〈/a〉〈br〉(Wegener, A.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0012.pdf"〉Berichtigung〈/a〉〈br〉(Jung, K.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0013.pdf"〉Illustration〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0014.pdf"〉Über die Polhöhenschwankungen infolge der Lorentz-Kontraktion der Erde〈/a〉〈br〉(Courvoisier, L.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0015.pdf"〉Zum Uhrvergleich auf drahtlosem Wege nach der Koinzidenzhörmethode〈/a〉〈br〉(Martin, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0016.pdf"〉Physikalische Grundlagen einer neuen geoelektrischen Aufschlußmethode〈/a〉〈br〉(Hummel, J. N.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0017.pdf"〉Untersuchung der Potentialverteilung für einen speziellen Fall im Hinblick auf geoelektrische Potentiallinienverfahren〈/a〉〈br〉(Hummel, J. N.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0018.pdf"〉Mächtigkeitsbestimmung von Deckschichten über Spalten durch Radioaktivitätsmessungen〈/a〉〈br〉(Koenigsberger, J.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0019.pdf"〉Zur Frage der regionalen, magnetischen Anomalien Deutschlands, insbesondere derjenigen Norddeutschlands〈/a〉〈br〉(Reich, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0021.pdf"〉Untersuchungen über die seismische Bodenunruhe kurzer Periode〈/a〉〈br〉(Schneider, W.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0022.pdf"〉Zur Theorie elektrischer Bodenforschung〈/a〉〈br〉(Heine, W.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0023.pdf"〉Emil Wiechert †〈/a〉〈br〉(Angenheister, G.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0024.pdf"〉Die topographische Reduktion bei Drehwagenbeobachtungen〈/a〉〈br〉(Numerov, B.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0025.pdf"〉Angewandte Seismik (Zusammenfassender Bericht über Arbeiten von 1921 bis 1928)〈/a〉〈br〉(v. Schmidt, O.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0027.pdf"〉Le problème des microséismes à groupes〈/a〉〈br〉(Gherzi, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0028.pdf"〉Zur Empfindlichkeitsbestimmung von magnetischen Variometern und zur Eichung der magnetischen Felder von Spulen〈/a〉〈br〉(Koenigsberger, J.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0029.pdf"〉Die Schrumpfungsgeschwindigkeit des Erdradius aus astronomischen Beobachtungen〈/a〉〈br〉(Meyermann, B.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0030.pdf"〉Über eine Verbindung zwischen den mondentägigen und den sonnentägigen Variationen der magnetischen Deklination〈/a〉〈br〉(Egedal, J.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0031.pdf"〉Die Zone der anormalen Hörbarkeit im kleinen〈/a〉〈br〉(Hiller, W.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0032.pdf"〉Mitteilungen〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0033.pdf"〉Ein graphisches Verfahren für Drehwagenmessungen zur Berechnung der Geländewirkung und der Wirkung beliebig gestalteter Massenkörper〈/a〉〈br〉(Haalck, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0035.pdf"〉Beiträge zur geoelektrischen Methode〈/a〉〈br〉(Hummel, J. N.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0036.pdf"〉Zum Uhrvergleich auf drahtlosem Wege nach der Koinzidenzhörmethode〈/a〉〈br〉(Mahnkopf, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0037.pdf"〉Berichtigung〈/a〉〈br〉(Meyermann, B.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0038.pdf"〉Zur Frage nach der Ursache von lokalen gravimetrischen und erdmagnetischen Störungen und ihre wechselseitigen Beziehungen〈/a〉〈br〉(Haalck, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0040.pdf"〉Gemeinschaftliche Arbeit zwischen Seismologen und Baufachmann zur Verringerung von Erdbebenschäden〈/a〉〈br〉(Briske, R.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0042.pdf"〉Feldapparatur zur Registrierung von Zeitzeichen〈/a〉〈br〉(Köhler, R.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0043.pdf"〉Über die Schmidtsche Methode der Bestimmung der Parameter von Stabmagneten〈/a〉〈br〉(Bock, R.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0046.pdf"〉Referate der Vorträge auf der Tagung der Deutschen Geophysikalischen Gesellschaft in Hamburg vom 19. bis 21. September 1928〈/a〉〈br〉(Koenigsberger, J.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0048.pdf"〉Die Seismizität der Ozeane und Kontinente〈/a〉〈br〉(Tams, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0049.pdf"〉Bodenunruhe durch Brandung und durch Frost〈/a〉〈br〉(Gutenberg, B.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0050.pdf"〉Beitrag zur Schallausbreitung in der Atmospähre〈/a〉〈br〉(Kölzer, J.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0051.pdf"〉Das Magnetfeld einer elektrischen Strömung im anisotropen leitenden Halbraum〈/a〉〈br〉(Müller, M.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0052.pdf"〉Die geführten elastischen Zweimittel-Wellen〈/a〉〈br〉(Uller, K.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0053.pdf"〉Vom Jahre 1922 an im südlichen Norwegen aufgenommene Nordlichtphotogramme〈/a〉〈br〉(Störmer, C.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0055.pdf"〉Zur Frage nach der Ursache von lokalen gravimetrischen und erdmagnetischen Störungen und ihre wechselseitigen Beziehungen〈/a〉〈br〉(Haalck, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0057.pdf"〉Vorträge, gehalten auf der Tagung der Deutschen Geophysikalischen Gesellschaft vom 19. bis 21. September 1928〈/a〉〈br〉(Seilkopf, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0060.pdf"〉Statistische Mechanik der Atmosphäre〈/a〉〈br〉(Baur, F.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0061.pdf"〉Das Schwadorfer Beben vom 8. Oktober 1927〈/a〉〈br〉(Conrad, V.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0062.pdf"〉Das Periodogramm der internationalen erdmagnetischen Charakterzahlen〈/a〉〈br〉(Wenzel Pollak, L.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0064.pdf"〉Der Stand der erdmagnetischen Forschung〈/a〉〈br〉(Schmidt, A.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0065.pdf"〉Magnetische Anomalien im westlichen Mecklenburg〈/a〉〈br〉(Schuh, F.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0066.pdf"〉Bemerkungen zur numerischen und graphischen Behandlung der Krümmungsgröße〈/a〉〈br〉(Jung, K.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0067.pdf"〉Der Wasserhaushalt der Antarktis in der Eiszeit〈/a〉〈br〉(Meinardus, W.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0068.pdf"〉Übersicht über Neuerscheinungen〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0069.pdf"〉Vortrage, gehalten auf der Tagung der Deutschen Geophysikalischen Gesellschaft vom 19. bis 21. September 1928〈/a〉〈br〉(Tams, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0071.pdf"〉Über kartographische Darstellung der Seismizität〈/a〉〈br〉(Renquist, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0072.pdf"〉Ergebnisse von Pilotaufstiegen im Gebiete von Island〈/a〉〈br〉(Georgi, J.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0073.pdf"〉Referat über die Polarfront- und Äquatorialfronttheorien〈/a〉〈br〉(Stüve, G.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0074.pdf"〉Die Messung der Horizontal- und der Vertikalintensität mit dem Magnetron〈/a〉〈br〉(Rössiger, M.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0075.pdf"〉Untersuchungen über die lokalen Schwankungen des Erdpotentials〈/a〉〈br〉(Stoppel, R.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0076.pdf"〉Klima und Klimatafel von Hamburg〈/a〉〈br〉(Perlewitz, P.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0077.pdf"〉Neue Ergebnisse über die Struktur des Windes (Vorläufige Mitteilung)〈/a〉〈br〉(Schmidt, W.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0079.pdf"〉Lokale und regionale magnetische Anomalien in Schleswig-Holstein〈/a〉〈br〉(Reich, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0080.pdf"〉Die optische Station in Simferopol〈/a〉〈br〉(Tichanowsky, J.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0081.pdf"〉Das Strömungssystem der Luft über dem tropischen Atlantischen Ozean nach den Höhenwindmessungen der Meteor-Expedition〈/a〉〈br〉(Kuhlbrodt, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0082.pdf"〉Ergebnisse und Aufgaben der meteorologischen Strahlungsmessungen〈/a〉〈br〉(Süring, R.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0083.pdf"〉Ergebnisse von Drehwaagemessungen in Schlewig-Holstein〈/a〉〈br〉(Jung, K.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0085.pdf"〉Aufsätze〈/a〉〈br〉(Lotze, F., Brockamp, B., Haalck, H., Myrbach, O., Whipple, Cabannes, J., Dufay, J., Gherzi, E., Pochettino, A., Rostagni, A.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0096.pdf"〉Mitteilungen〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0097.pdf"〉Autorenverzeichnis〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0098.pdf"〉Sachverzeichnis〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0099.pdf"〉Literaturverzeichnis〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0100.pdf"〉Geophysikalische Berichte〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0004/LOG_0101.pdf"〉Register der Goephysikalische Berichte〈/a〉〈/li〉 〈/body〉 〈/html〉
    Description: research
    Description: DGG, DFG, SUB Göttingen
    Keywords: 550 ; Geophysik ; Physische Geografie ; Atmosphäre ; Aurora ; Deutschland ; Elektromagnetismus ; Erdebeben ; Geoelektrik ; Geomagnetismus ; Gravimetrie ; Gravitation ; Island ; Klima ; Meteorologie ; Norwegen ; Polwanderung ; Seismik ; Tektonik ; Zeit ; FID-GEO-DE-7
    Language: German , English , French
    Type: anthology_digi
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  • 16
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    Friedr. Vieweg & Sohn, Braunschweig
    In:  SUB Göttingen | 8 GEOGR PHYS 203
    Publication Date: 2021-03-29
    Description: Dieser Band enthält 77 Beiträge zu Themengebieten der Physik der festen Erde, des magnetischen und elektrischen Felds der Erde, der Physik der Atmosphäre sowie der Angewandten Geophysik, veröffentlicht durch die Deutsche Geophysikalische Gesellschaft in den Jahren 1930.
    Description: 〈html〉 〈body〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0004.pdf"〉Titelseite〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0005.pdf"〉Ein neuer Vierpendelapparat für relative Schweremessungen〈/a〉〈br〉(Meisser, O.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0007.pdf"〉Geophysikalische Messungen unter Tage〈/a〉〈br〉(Meisser, O., Wolf, F.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0008.pdf"〉Die ersten Dickenmessungen des grönländischen Inlandeises〈/a〉〈br〉(Sorge, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0010.pdf"〉Die seismische Bodenunruhe in Hamburg und ihr Zusammenhang mit der Brandung〈/a〉〈br〉(Mendel, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0012.pdf"〉Die sonnenbelichteten Nordlichtstrahlen und die Konstitution der höheren Atmosphärenschichten〈/a〉〈br〉(Vegard, L.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0013.pdf"〉Nochmals: Zur Frage der Laufzeitkurven〈/a〉〈br〉(Gutenberg, B.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0014.pdf"〉Erwiderung zur vorstehenden Arbeit von Herrn Prof. Gutenberg〈/a〉〈br〉(Krumbach, G.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0015.pdf"〉Bemerkungen zu der vorstehenden Erwiderung〈/a〉〈br〉(Gutenberg, B.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0016.pdf"〉Einfluß des Mondes auf die erdmagnetischen Elemente in Samoa〈/a〉〈br〉(Fanselau, G.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0017.pdf"〉Ein Diagramm zur Bestimmung der Differenz der Schwerestörung 〈i〉Δg〈/i〉 in zwei Beobachtungspunkten〈/a〉〈br〉(Oserezky, W.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0018.pdf"〉Zur Ermittlung ausgedehnter Schichten verschiedener Leitfähigkeit〈/a〉〈br〉(Koenigsberger, J.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0019.pdf"〉Über tägliche erdmagnetische Variationen in zwei Alpentälern〈/a〉〈br〉(Koenigsberger, J.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0020.pdf"〉Die Wirkung der obersten Erdschicht auf die Anfangsbewegung einer Erdbebenwelle〈/a〉〈br〉(Hasegawa, M.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0021.pdf"〉Über die Elastizität von Gesteinen〈/a〉〈br〉(Breyer, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0023.pdf"〉Über den Horizontalabstand von Pendelstationen〈/a〉〈br〉(Schwinner, R.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0024.pdf"〉Die Belowsche Methode zur Bestimmung der Wirkung gegebener Massen auf Krümmungsgröße und Gradient, ihre Verallgemeinerung für beliebige Massenformen und ihre Anwendung auf "zweidimensionale" Massenanordnungen〈/a〉〈br〉(Jung, K.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0028.pdf"〉Harmonische Schwingungen des Untergrundes〈/a〉〈br〉(Köhler, R.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0029.pdf"〉Mitteilungen〈/a〉〈br〉(Fleming, I. A., Linke, F.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0030.pdf"〉Über die Ursache der erdmagnetischen Störung im Gebiet der Freien Stadt Danzig〈/a〉〈br〉(Haalck, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0031.pdf"〉Die kontinentalen Verschiebungen von Amerika und Madagaskar〈/a〉〈br〉(Livländer, R.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0032.pdf"〉Magnetische Vermessung einiger tertiärer Eruptivgänge und -stöcke im sächsischen Elbsandsteingebirge〈/a〉〈br〉(Schulze, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0033.pdf"〉Über die Existenz einer mondentägigen Variation in den Erdströmen〈/a〉〈br〉(Egedal, J.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0034.pdf"〉Zum Trübungsfaktor〈/a〉〈br〉(Feussner, K., Friedrichs, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0035.pdf"〉Temperature changes between Torsion balance readings in the State of Texas〈/a〉〈br〉(Harris, S.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0036.pdf"〉Über isostatische Schwereanomalien und deren Beziehung zu den totalen Anomalien〈/a〉〈br〉(Jung, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0037.pdf"〉Bemerkungen zu den Ausführungen von H. Jung〈/a〉〈br〉(Ansel, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0038.pdf"〉Mitteilungen〈/a〉〈br〉(Linke, F.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0040.pdf"〉Wesensgleiche und wesensverschiedene Darstellungen〈/a〉〈br〉(Nippoldt, A.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0041.pdf"〉Die Säkularvariation in der Rheinpfalz in den Jahren 1850 bis 1928〈/a〉〈br〉(Burmeister, F.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0042.pdf"〉Größenverhältnis von remanentem zu induziertem Magnetismus in Gesteinen; Größe und Richtung des remanenten Magnetismus〈/a〉〈br〉(Koenigsberger, J.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0043.pdf"〉Über eine magnetische Anomalie am Lebasee in Ostpommern〈/a〉〈br〉(Reich, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0045.pdf"〉Die Ergebnisse der magnetischen Messungen in der Ostsee in den Jahren 1924 bis 1929〈/a〉〈br〉(v. Gernet-Reval, A.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0047.pdf"〉Erdmagnetische Messungen in Bulgarien, Mazedonien, Trazien und in der Dobrudja〈/a〉〈br〉(Popoff, K.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0048.pdf"〉Einige Bemerkungen über erdmagnetische Messungen, welche in Feodossia ausgeführt wurden〈/a〉〈br〉(Palazzo, L.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0049.pdf"〉Possible causes of abnormal polarizations of magnetic formations〈/a〉〈br〉(Heiland, C.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0050.pdf"〉Die geologische Bedeutung der Schaffung einer Isanomalenkarte der magnetischen Vertikalintensität von Deutschland〈/a〉〈br〉(Schuh, F.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0051.pdf"〉Die innere Genauigkeit von Inklinationsmessungen mit dem Erdinduktor〈/a〉〈br〉(Venske, O.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0052.pdf"〉Theorie einer neuen galvanischen Waage〈/a〉〈br〉(Bock, R.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0053.pdf"〉Messungen im Luftschiff〈/a〉〈br〉(Haussmann, K.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0054.pdf"〉Une modification de l'enregistreur à marche rapide et à petite consommation de papier de Ad. Schmidt pour l'application aux stations de l'Anneé Polaire 1932–1933〈/a〉〈br〉(la Cour, D.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0056.pdf"〉Was sagen uns die Parameter eines Magneten?〈/a〉〈br〉(Fanselau, G.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0057.pdf"〉Über die Herleitung des Potentials des täglichen erdmagnetischen Variationsfeldes〈/a〉〈br〉(Egedal, J.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0058.pdf"〉Über den Vektor der magnetischen Störungen im aperiodischen Verlauf〈/a〉〈br〉(Keränen, J.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0059.pdf"〉Forschungsmethode über den Zusammenhang zwischen der Sonnenfleckentätigkeit und den erdmagnetischen Störungen〈/a〉〈br〉(Gehlinsch, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0060.pdf"〉Der Temperaturverlauf im Sandboden〈/a〉〈br〉(Süring, R.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0061.pdf"〉Die dominierende Luftdruckwelle des strengen Winters 1928/29〈/a〉〈br〉(Weickmann, L.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0063.pdf"〉Über einige meteorologische Begriffe〈/a〉〈br〉(Tetens, O.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0066.pdf"〉Über die Feinstruktur des Temperaturgradienten längs Berghängen〈/a〉〈br〉(Wagner, A.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0067.pdf"〉Das unperiodische Element im Tropenklima〈/a〉〈br〉(Knoch, K.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0068.pdf"〉Zur Theorie der Maxwellschen Geschwindigkeitsverteilung in turbulenten Strömungen〈/a〉〈br〉(Ertel, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0069.pdf"〉Wie tief dringen die Polarlichter in die Erdatmosphäre ein?〈/a〉〈br〉(Störmer, C.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0072.pdf"〉Gammastrahlen an Kaliumsalzen〈/a〉〈br〉(Kolhörster, W.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0073.pdf"〉Über die Form der Fernschallwelle〈/a〉〈br〉(Kühl, W.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0074.pdf"〉Die Seismizität des Südantillenbogens〈/a〉〈br〉(Tams, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0076.pdf"〉Eine neue württembergische Erdbebenwarte〈/a〉〈br〉(Kleinschmidt, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0077.pdf"〉Über den Zusammenhang zwischen Typhusmorbidität (bzw. Typhusmortalität) und Niederschlagsschwankungen nebst einer Kritik der Brücknerschen Klimaperiode〈/a〉〈br〉(Wenzel Pollak, L.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0079.pdf"〉Über die Abhängikeit der Schwerkraft vom Zwischenmedium〈/a〉〈br〉(Schlomka, T.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0080.pdf"〉On the Determination of the Lunar Atmospheric Tide〈/a〉〈br〉(Chapman, S.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0081.pdf"〉Die Wärmeumsatz durch die Wärmestrahlung des Wasserdampfes in der Atmosphäre〈/a〉〈br〉(Albrecht, F.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0082.pdf"〉Ein Universal-Induktionsmagnetometer〈/a〉〈br〉(Uljanin, W.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0083.pdf"〉Der große Staubfall vom 26. bis 29. April 1928 in Südosteuropa〈/a〉〈br〉(Stenz, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0085.pdf"〉Ein neues Verfahren der luftelektrischen Raumladungsmessung〈/a〉〈br〉(Wigand, A., Schubert, J., Frankenberger, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0086.pdf"〉Kurze Erwiderung auf Vegards Bemerkungen über sonnenbelichtete Nordlichtstrahlen〈/a〉〈br〉(Störmer, C.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0088.pdf"〉Die Invariabilität und Abstimmung von Minimumpendeln〈/a〉〈br〉(Kohlschütter, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0089.pdf"〉Bemerkung zu der Arbeit "Die Invariabilität und Abstimmung von Minimumpendeln" von E. Kohlschütter〈/a〉〈br〉(Meisser, O.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0090.pdf"〉Erwiderung〈/a〉〈br〉(Kohlschütter, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0091.pdf"〉Bemerkungen zu der Arbeit von Herrn Dr. O. Meisser: "Ein neuer Vierpendelapparat für relative Schweremessungen"〈/a〉〈br〉(Heiland, C.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0092.pdf"〉Bemerkungen zu den vorstehenden Ausführungen von Herrn Prof. Dr. C. A. Heiland〈/a〉〈br〉(Meisser, O.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0093.pdf"〉Das Epizentrum des südatlantischen Großbebens vom 27. Juni 1929〈/a〉〈br〉(Tams, E.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0094.pdf"〉Seismische Untersuchungen auf dem Pasterzegletscher. I〈/a〉〈br〉(Brockamp, B., Mothes, H.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0096.pdf"〉Bericht über die neunte Tagung der Deutschen Geophysikalischen Gesellschaft vom 11. bis 14. September 1930 in Potsdam〈/a〉〈br〉(Mügge, Linke, F.)〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0097.pdf"〉Autorenverzeichnis〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0098.pdf"〉Sachverzeichnis〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0099.pdf"〉Literaturverzeichnis〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0100.pdf"〉Geophysikalische Berichte〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0101.pdf"〉Register der Geophysikalischen Berichte〈/a〉〈/li〉 〈li〉〈a href="https://gdz.sub.uni-goettingen.de/download/pdf/PPN101433392X_0006/LOG_0102.pdf"〉Mitgliederverzeichnis der Deutschen Geophysikalischen Gesellschaft nach dem Stande vom 1. Oktober 1930〈/a〉〈/li〉 〈/body〉 〈/html〉
    Description: research
    Description: DGG, DFG, SUB Göttingen
    Keywords: 550 ; Geophysik ; Physische Geografie ; Atmosphäre ; Aurora ; Deutschland ; Erdbeben ; Geoelektrik ; Geologie ; Geomagnetismus ; Gravimetrie ; Gravitation ; Ionosphäre ; Magnetismus ; Pendel ; Seismik ; Tiden ; USA ; FID-GEO-DE-7
    Language: German , English , French
    Type: anthology_digi
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  • 17
    Call number: PIK C 329-19-92388
    Keywords: Deutschland ; Vergaberecht ; Deutschland ; Vergaberecht
    Type of Medium: Monograph available for loan
    Pages: LXIV, 614 Seiten , 20 cm
    Edition: 20. Auflage, Stand: 1. Januar 2018, Sonderausgabe
    ISBN: 9783423055956 , 9783406722059
    Series Statement: dtv 5595
    Language: German
    Branch Library: PIK Library
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  • 18
    Publication Date: 2021-03-29
    Description: Abstract: Current information on the potential distribution and condition of peatland soils are of great importance. This applies notably for actions with respect to climate and environmental protection. The Ministry of infrastructure and agriculture in the federal state of Brandenburg (MIL) therefore initiated a project to provide a complete and updated map of peatland soils for the federal state of Brandenburg, Germany, for the year 2013. Extensive legacy data on both, areal extent of peatland soils as well as soil profile information where made digitally available in a homogeneous map and a consistent database. Approximately 7.725 sites were randomly selected from legacy soil data and currently reinvestigated to draw inference on the current condition of peatland soils. Statistically derived peatland subsidence rates at grassland sites of 0.50 cm/yr and 0.57 cm/yr at arable sites fit well with published values in comparable regions of central Europe. Our results prove the great dynamics of soil development on agriculturally used peatlands. Concerning Brandenburg, the area of peatland soils decreased from 270.000 ha in the early 20th century (Prussian geological map) to actually 163.000 ha.
    Description: Zusammenfassung: Aktuelle Informationen zur Verbreitung und zum Zustand der Moorböden sind vor dem Hintergrund der geplanten Einführung von Agrarumwelt- und Klimamaßnahmen in der Landwirtschaft von besonderer Bedeutung. Das Ministerium für Infrastruktur und Landwirtschaft des Landes Brandenburg (MIL) hat hierzu das Projekt „Schaffung einer Datengrundlage für die Ableitung von Agrarumwelt- und Klimamaßnahmen auf Moorstandorten in Brandenburg“ initiiert. Mit dem Ziel der Bereitstellung einer auf das Jahr 2013 bezogenen Moorkarte wurden umfangreiche, bis dato nicht genutzte Datenbestände zur Verbreitung von Moorböden in Brandenburg zu einer überschneidungsfreien Karte und umfassenden Datenbank moorbodenkundlicher Bodenprofile verarbeitet. Um den aktuellen Zustand der Moorböden zu erfassen, wurden flächenrepräsentativ und zufällig an 7.725 Standorten mit ausreichender Datenbasis erneut bodenkundliche Erhebungen durchgeführt und statistisch ausgewertet. Im Ergebnis konnten Mächtigkeitsverlustraten für landwirtschaftlich genutzte Moorstandorte in Brandenburg abgeleitet werden. Für flachgründige Niedermoorstandorte unter Grünland liegen sie bei 0,50 cm/a, vergleichbare ackerbaulich genutzte Standorte liegen mit 0,57 cm/a darüber. Dies deckt sich gut mit publizierten Werten an vergleichbaren Standorten in Zentraleuropa. Die Fläche der Moorböden in Brandenburg hat sich von Anfang des 20. Jahrhunderts von 270.000 ha, ausgewiesen auf Basis der Preußisch geologisch-agronomische Karte (PGK), auf heute noch 163.000 ha reduziert.
    Description: DFG, SUB Göttingen, DGMT
    Description: research
    Keywords: 553.21 ; Moor ; peatland ; Brandenburg ; Deutschland ; Germany ; FID-GEO-DE-7
    Language: German
    Type: article , publishedVersion
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  • 19
    Publication Date: 2021-03-29
    Description: Abstract: Peatlands are intensively exchanging greenhouse gases with the free atmosphere. Natural peatlands, mires, sequester carbon dioxide as carbon in the peat and emit methane. Peatlands under agriculture or forest are mostly drained and emit carbon dioxide due to peat mineralization and nitrous oxide due to fertilization and nitrogen mineralization. In order to characterize the actual situation and to evaluate measures for the reduction of greenhouse gas emissions measured values on gas exchange are needed. Within two national projects direct measurements of the greenhouse gas exchange have been conducted on a wide range of sites, covering different peatland types, land use forms and hydrological situations and using a standardized methodology. Between 2007 and 2012 22 sites have been studied in Lower Saxony over at least two years using the closed cover method. An overview on sites and results is given. Moreover, approaches to estimate the greenhouse gas emissions due to peat excavation and horticultural peat use are presented. Own emission factors and data from literature are used to estimate the contribution of peatlands and peat use to the greenhouse gas emissions of Lower Saxony. Finally measures for the reduction of greenhouse gas emissions are discussed and estimates on reduction costs are given from examples.
    Description: Zusammenfassung: Moore stehen in einem intensiven Gasaustausch mit der Atmosphäre. Natürliche Moore haben über Jahrtausende Kohlendioxid aufgenommen und den Kohlenstoff als Torf gespeichert. Dabei haben sie Methan abgegeben. Entwässerte und genutzte Moore setzen den Kohlenstoff als Kohlendioxid wieder frei und emittieren zudem klimarelevantes Lachgas als Ergebnis der Stickstoffdüngung und der Torfmineralisation. Zur Charakterisierung der Ist-Situation und zur Beurteilung von Maßnahmen ist es erforderlich, belastbare Daten über die Treibhausgasemissionen der Moore zu haben. Im Rahmen von zwei bundesweit angelegten Verbundvorhaben wurden an einer Vielzahl von Standorten unterschiedlichen Moortyps, unterschiedlicher Nutzung und unterschiedlicher Klima- und Wasserregime mit einer abgestimmten Methodik die Flüsse der wesentlichen Treibhausgase direkt gemessen. Im Rahmen dieser Verbundvorhaben wurden in Niedersachsen zwischen 2007 und 2012 an 22 Standorten mindestens zweijährige Messungen mit der Haubentechnik vorgenommen. Dieser Beitrag gibt einen Überblick über untersuchte Standorte und Messergebnisse. Darüber hinaus werden Ansätze zur Ermittlung der Treibhausgasemissionen aus der industriellen Torfgewinnung dargestellt. Unter Verwendung eigener Ergebnisse und von Literaturdaten wird eine Abschätzung der Treibhausgasemissionen aus Moor und Torfgewinnung für das Land Niedersachsen vorgenommen. Abschließend geht der Beitrag auf Maßnahmen zur Verminderung der Treibhausgasemissionen aus Mooren sowie beispielhaft auf Emissionsminderungskosten ein.
    Description: DFG, SUB Göttingen, DGMT
    Description: research
    Keywords: 553.21 ; Moor ; mire ; peatland ; emission ; CO2 ; N2O ; Germany ; Deutschland ; FID-GEO-DE-7
    Language: German
    Type: article , publishedVersion
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  • 20
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    Inst. für Phys. Geogr., Freie Univ., Berlin
    In:  Herausgeberexemplar (FU Berlin) | ZB 20559:36
    Publication Date: 2021-03-29
    Description: STÄBLEIN, G.: Regionale Geomorphologie ; KERTESZ, A.: Geomorphologische Kartierung in der Bundesrepublik Deutschland und in Ungarn. Ein Vergleich der Methodik ; BOLLMANN, I.: Geomorphologische Daten und kartographische Darstellung ; PACHUR, H.-J. & RÖPER, H.-P.: Geolimnologische Befunde des Berliner Raumes ; REMMELE, G.: Holozäne Morphodynamik an Schichtstufenhängen — Untersuchungen in Nordwest-Irland ; MÜLLER, MJ. & STRASSER, R.: Holozäne Geomorphodynamik und Landschaftsentwicklung am Ostrand der Trier-Luxemburger Mulde ; KLEBER, A.: Zur jungtertiären Reliefentwicklung im Vorland der südlichen Frankenalb ; HAMANN, C.: Windwurf als Ursache der Bodenbuckelung am Südrand des Tennengebirges, ein Beitrag zur Genese der Buckelwiesen ; ZÖLLER, L.: Neotektonik am Hunsrückrand ; SEPPÄLÄ, M.: Glazialhydrologie des Inlandeises, eine geomorphologische Interpretation der Verhältnisse in Finnland ; JÄKEL, D.: Untersuchungen und Analysen zur Entstehung der Hamada ; GARLEFF, K. & STINGL, H.: Neue Befunde zur jungquartären Vergletscherung in Cuyo und Patagonien ; STINGL, H. & GARLBFF, K.: Tertiäre und pleistozäne Reliefentwicklung an der interozeanischen Wasserscheide in Südpatagonien (Gebiet von Rio Turbio, Argentinien) ; SCHMIDT, K.H.: Nachweis junger Krustenbewegungen auf dem Colorado Plateau, USA ; KUHLE, M.: Zur Geomorphologie Tibets, Bortensander als Kennformen semiarider Vorlandvergletscherung . ; STÄBLEIN, G.: Deutscher Arbeitskreis für Geomorphologie ;
    Description: research
    Description: DFG, SUB Göttingen, FU Berlin
    Keywords: 550 ; 910.02 ; Geomorphologie ; Kartierung ; Holocene ; Irland ; Hunsrück ; Frankenalb ; Finnland ; Hamada ; Patagonien ; Cuyo ; Colorado ; Tektonik ; Gletscher ; glacier ; Tibet ; Deutschland ; Sahara ; Tibesti ; Darfur ; Sudan ; Libyen ; FID-GEO-DE-7
    Language: German
    Type: anthology_digi
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  • 21
    Publication Date: 2021-03-29
    Description: Abstract: In addition to the widespread use of peatlands for agricultural purposes, which is also common in other German states, the raised bogs in Lower Saxony are still also used up to the present day for housing, as well as for industrial peat extraction. The Peatland Conservation Programme in Lower Saxony launched in 1981 therefore only covered raised bogs to disentangle the different uses, and to systematise the nature protection activities in raised bogs. The priority areas for the extraction of peat defined in the Federal State Regional Planning Programme are to be rescinded. The new State Development Programme being formulated will not only include the nature conservation of peatlands, but also for the first time, deal with the climate protection afforded by these very important storage areas for carbon. An important aspect in this regard is the incorporation of fens, and the discharge from peatlands into underlying water bodies. The database and the conclusions which contribute to the implementation of climate protection in peatland conservation programmes, will be discussed and compared with the peatland conservation previously implemented pursuant to the Peatland Conservation Programme in Lower Saxony. An overview describes various approaches for peatland and climate protection implemented by private initiatives, nature conservation societies, EU-Life-Projects, contractual nature protection, publicly owned businesses and authorities in Lower Saxony, research projects on alternative uses, and climate certificate trading. These varied instruments are compared to highlight their relative areal effectiveness, and relevance, followed by an estimate of the potential for future peatland and climate protection in Lower Saxony.
    Description: Zusammenfassung: Neben der auch in anderen Bundesländern weit verbreiteten landwirtschaftlichen Nutzung von Mooren werden die niedersächsischen Hochmoore bis heute auch als Siedlungsraum und zur industriellen Torfgewinnung genutzt. Daher umfasste das niedersächsische Moorschutzprogramm von 1981 nur die Hochmoore, um diese verschiedenen Nutzungen zu entflechten und den Naturschutz in Hochmooren zu systematisieren. Die bisher im Landesraumordnungsprogramm ausgewiesenen Vorranggebiete für die Rohstoffgewinnung von Torf sollen gestrichen werden. In ein neu aufzustellendes Landesentwicklungsprogramm soll neben dem Naturschutz von Mooren erstmalig auch der Klimaschutz dieser wichtigen Kohlenstoffspeicher eingehen. Von besonderer Bedeutung sind hierbei die Einbeziehung der Niedermoore und der Stoffaustrag aus Mooren in unterliegende Gewässer. Die Datengrundlagen und Schlussfolgerungen, die zur Implementierung des Klimaschutzes in den Moorschutz beitragen, werden diskutiert und mit dem bisher umgesetzten Moorschutz nach dem niedersächsischen Moorschutzprogramm verglichen. Ein Überblick beschreibt verschiedene Ansätze zum Moor- und Klimaschutz von Privatinitiativen, von Naturschutzverbänden, mit EU-Life-Projekten, im Vertragsnaturschutz, von niedersächsischen Landesbetrieben und Behörden, von Forschungsprojekten zu alternativen Nutzungen und beim Handel mit Klima-Zertifikaten. Diese unterschiedlichen Instrumente werden in ihrer Flächenwirksamkeit und Relevanz in Beziehung gesetzt und das Potenzial für den künftigen Moor- und Klimaschutz in Niedersachsen abgeschätzt.
    Description: DFG, SUB Göttingen, DGMT
    Description: research
    Keywords: 553.21 ; Moor ; peatland ; mire ; nature conservation ; Germany ; Deutschland ; emission ; bog ; Niedersachsen ; FID-GEO-DE-7
    Language: German
    Type: article , publishedVersion
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  • 22
    Call number: IASS 15.89489
    Keywords: Deutschland ; Vergaberecht
    Type of Medium: Monograph available for loan
    Pages: CVII, 1774 S. , 240 mm x 160 mm
    ISBN: 9783406628597 (Gb.) , 3406628591
    Language: German
    Branch Library: IASS Library
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  • 23
    Monograph available for loan
    Monograph available for loan
    Köln : Bundesanzeiger-Verl.
    Call number: IASS 15.89492
    Keywords: Deutschland ; Vergaberecht ; Einführung
    Type of Medium: Monograph available for loan
    Pages: 247 S. , graph. Darst
    ISBN: 3846200123 , 9783846200124 , 9783846200131 (electr.; eBook)
    Series Statement: Vergabe
    Language: German
    Branch Library: IASS Library
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  • 24
    Call number: IASS 15.89620
    Keywords: Deutschland ; Großbritannien ; Klimaänderung ; Klimaschutz ; Technikbewertung ; Politische Auseinandersetzung
    Type of Medium: Monograph available for loan
    Pages: 263 S. , Ill., graph. Darst. , 210 mm x 148 mm, 351 g
    ISBN: 3658053658 (pbk.) , 9783658053659 (pbk.)
    Language: German
    Note: Univ., Diss.--Heidelberg, 2013
    Branch Library: IASS Library
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  • 25
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    In:  ???
    Publication Date: 2013
    Description: Simulationen mithilfe des Models 4C zu möglichen Auswirkungen der Klimaänderungen des RCP 8.5 Klimaszenariums auf Wälder in Deutschland Kiefer Fichte Eiche Buche KATASTER-BESCHREIBUNG: Auswirkungen des Klimawandels (Temperatur, Niederschlag, CO2-Gehalt der Atmosphäre) auf die Wälder KATASTER-DETAIL: Delta T (Frühjahr) + und Delta Nied (Frühjahr) -, dann Produktivität der Wälder -; Delta C02 + um 25 - 30 %, dann Produktion der Wälder + um 9 - 20%; Delta T + (an nicht wasserlimitierten Standorten), dann Produktivität der Wälder +; Delta CO2+, dann Wassernutzungseffizienz der Wälder +; Delta T (Sommer) +, dann Waldbrandgefahr +; Delta T (Sommer) + und Delta Nied (Sommer) - (= WaBi -), dann Trockenstress der Wälder + um bis zu 9% und dann Produktivität der Wälder -; Delta T (Sommer) + und Delta Nied (Sommer) -, dann Populationsdichte Kiefern-Großschädlinge +;
    Keywords: Deutschland ; 20. und 21. Jahrhundert ; Boden ; Buche ; Eiche ; Fichte ; Forst ; Kiefer ; Klima ; Niederschlag ; Pflanzenschädling ; Phänologie ; Sturmschaden ; Temperatur ; Trockenheit ; Verdunstung ; Waldbrand ; Waldwachstum ; Wassermangel ; Wind ; Grundwasser ; Modell
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  • 26
    Publication Date: 2012
    Description: Übersicht über bisherige, dokumentiere Zusammenhänge einer Klimaänderung und pilzliche Krankheiten in Raps, Abschätzungen über das Auftreten von Verticillium longisporum, Sclerotinia sclerotiorum, Alternaria brassicae und Phoma lingam an Raps in der Zukunft KATASTER-BESCHREIBUNG: Projektionen über das Auftreten von pilzlichen Pathogenen in Raps, Basiszeitraum 1971-2000, Szenario A1B, REMO, 2001-2030 und 2071-2100, Zusammenhang zwischen Grad-Tagen(〉0°C), Pflanzenentwicklung und Krankheitsparametern als Regressionsfunktionen im Artikel, jedoch sind feiner aufgelöste Projektion von RCM als Tageswerte erforderlich, um Wachstumszyklen zu simulieren und genauere Aussagen zu erhalten KATASTER-DETAIL: Delta T +, dann Zunahme von Verticillium longisporum, Sclerotinia sclerotiorum, Alternaria brassicae und Phoma lingam an Raps, Signal verstärkt im Szenarienzeitraum 2071-2100, Abnahme von Pyrenopeziza brassicae
    Keywords: Deutschland ; Sachsen, Niedersachsen, Norddeutschland ; 1971-2000 ; Szenarien ; Infektionskrankheiten ; Temperatur ; Raps
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  • 27
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    In:  Hattermann, F. F., Z. W. Kundzewicz, H. S., T. Vetter, W. Kron, O. Burghoff, Y. Hauf, V. Krysanova, F.-W. Gerstengarbe, P. Werner, B. Merz, A. Bronstert (2012a), Flood risk in holistic perspective - observed changes in Germany. In: Changes of flood risk in Europe, IAHS Press, Wallingford, 212-237.
    Publication Date: 2012
    Description: Simulierte und beobachtete Trends der jährlichen Hochwassermaxima KATASTER-BESCHREIBUNG: Trend der Zu- bzw. Abnahme der Andauer der jährlichen Hochwassermaxima in Deutschland für die Vergangenheit KATASTER-DETAIL: Abnahme des mittleren jährlichen Abflusses um 35 % in Baden-Württemberg (Pegel Achstetten/Baierzer Rot) bzw. 21 % in Brandenburg (Pegel Ketzin/Havel) Zunahme des mittleren jährlichen Abflusses um 84 % in Bayern (Pegel Breitenbachkamm/Breitach) bzw. 74 % in Bayern (Pegel Kalteneck/Ilz)
    Keywords: Deutschland ; 1951-2003 ; Witterungsextreme ; Hochwasser
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  • 28
    Call number: IASS 15.89488
    Keywords: Deutschland ; Forschung und Entwicklung ; Vertragsrecht
    Type of Medium: Monograph available for loan
    Pages: 183 S. , Ill., graph. Darst. , 22 cm
    ISBN: 9783415046658 (Pp.)
    Language: German
    Branch Library: IASS Library
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  • 29
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    In:  Internes Arbeitsmaterial des PIK, .... fs01/guests\Martin.Wodinski\PIK-COLLECTION\SLIDES-POOL\RD2\
    Publication Date: 2010
    Description: Kalkulation der Hitzetage (Tmax 〉 30°C) anhand es PIK/DWD Datensatzes für 1951-2006 im Jahr, und für den Zeitraum 2051-60, Szenario A1B, als Mittel und Differenzkarten KATASTER-BESCHREIBUNG: Hitzetage (Tmax 〉 30°C) in Deutschland KATASTER-DETAIL: Zunahme der Hitzetage (Tmax 〉 30°C) 2051-2060 vs. 1951-2006 um bis zu 16 Tagen im Jahr, stärkste Zunahme Rheingragben, Rheinland-Pfalz, Niederrhein, Kölner Bucht und Mitteldeutschland
    Keywords: Deutschland ; 1951-2006, 2051-60 ; Temperatur ; Witterungsextreme
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  • 30
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    In:  Internes Arbeitsmaterial des PIK, .... fs01/guests\Martin.Wodinski\PIK-COLLECTION\SLIDES-POOL\RD2\
    Publication Date: 2010
    Description: Kalkulation der Klimatischen Wasserbilanz (mm) anhand es PIK/DWD Datensatzes für 1951-2006 im Jahr, und für den Zeitraum 2051-60, Szenario A1B, als Mittel und Differenzkarten KATASTER-BESCHREIBUNG: Jährliche Klimatischen Wasserbilanz WABI (Niederschlag - pot. Verdunstung nach Turc-Ivanov) für Deutschland KATASTER-DETAIL: Zu- bzw. Abnahme der (WABI) 2051-2060 vs. 1951-2006 von 200 - (-100) im Westen der BRD, in Ostdeutschland stärkere, einheitliche Abnahme der WABI um bis zu 300mmm
    Keywords: Deutschland ; 1951-2006, 2051-60 ; Niederschlag ; Temperatur ; Witterungsextreme
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  • 31
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    In:  In: BfS/BfR/RKI/UBA (Hrsg.): Klimawandel und Gesundheit. UMID – UmweltMedizinischerInformationsDienst, Ausgabe 3 (Themenheft), Dezember 2009, 13-16
    Publication Date: 2009
    Description: Beispiele Ambrosia, Eichenprozessionsspinner KATASTER-BESCHREIBUNG: KATASTER-DETAIL:
    Keywords: Deutschland ; Umweltmedizin ; Phänologie
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  • 32
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    In:  In: BfS/BfR/RKI/UBA (Hrsg.): Klimawandel und Gesundheit. UMID – UmweltMedizinischerInformationsDienst, Ausgabe 3 (Themenheft), Dezember 2009, 17-20
    Publication Date: 2009
    Description: ausgedehnte Ambrosiaareale auch in der Lausitz und dem Berliner Raum KATASTER-BESCHREIBUNG: Neben Sensibilisierung gegen Ambrosia auch Kreuzreationen bei Sensibilisierung gegen Beifuß möglich KATASTER-DETAIL:
    Keywords: Deutschland ; Umweltmedizin ; Phänologie
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  • 33
    Publication Date: 2009
    Description: einheimische und importierte  vektorassoziierte  Infektionen, Gastrointestinale  Infektionskrankheiten KATASTER-BESCHREIBUNG: KATASTER-DETAIL:
    Keywords: Deutschland ; Umweltmedizin ; Infektionskrankheiten
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  • 34
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    In:  In: BfS/BfR/RKI/UBA (Hrsg.): Klimawandel und Gesundheit. UMID – UmweltMedizinischerInformationsDienst, Ausgabe 3 (Themenheft), Dezember 2009, 21-23
    Publication Date: 2009
    Description: weltweite Verbreitung der Asiatischen Tigermücke Aedes albopictus innerhalb der letzten zwei Jahrzehnte im Zusammenhang mit Chikungunya-Ausbruch im Sommer 2007 in Italien KATASTER-BESCHREIBUNG: Transportwege der Globalisierung als wesentlicher Faktor neben Klimaänderungen KATASTER-DETAIL:
    Keywords: Deutschland ; Umweltmedizin ; Infektionskrankheiten
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  • 35
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    In:  In: BfS/BfR/RKI/UBA (Hrsg.): Klimawandel und Gesundheit. UMID – UmweltMedizinischerInformationsDienst, Ausgabe 3 (Themenheft), Dezember 2009, 24-28
    Publication Date: 2009
    Description: Gesundheitliche Bewertung ultravioletter Strahlung KATASTER-BESCHREIBUNG: KATASTER-DETAIL:
    Keywords: Deutschland ; Umweltmedizin ; UV-Strahlung
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  • 36
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    In:  Kappas, M. (Hrsg): Klimawandel und Hautkrebs, Interdisziplinäre Projektgruppe CLIMAderm, Stuttgart, ibidem-Verlag, 25-51
    Publication Date: 2008
    Keywords: Deutschland ; Umweltmedizin ; UV-Strahlung
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  • 37
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    In:  JDDG - Journal der Deutschen Dermatologischen Gesellschaft, 2008, 6(8), 632-639
    Publication Date: 2008
    Description: Klärung der Studienlage zum potentiellen Einfluss des Klimawandels auf die Prävalenz von Haut- und Allergieerkrankungen in Deutschland KATASTER-BESCHREIBUNG: klimabedingte Veränderungen vor allem bei allergischen Erkrankungen, Hautkrebs und einzelnen erregerbedingten Dermatosen KATASTER-DETAIL:
    Keywords: Deutschland ; Umweltmedizin ; Phänologie ; UV-Strahlung
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  • 38
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    In:  In: Lozán, J.L.; Graßl, H.; Jendritzky, G.; Karbe, L.; Reise, K. (Hrsg.) Warnsignal Klima: Gesundheitsrisiken. Gefahren für Pflanzen, Tiere und Menschen.Wissenschaftliche Auswertungen, Hamburg, 121-125
    Publication Date: 2008
    Description: Fallbeispiel Sommer 2003 KATASTER-BESCHREIBUNG: Zunahme von Ozon in der Troposphäre bei stationären sommerlichen Hochdruckwetterlagen mit hohen Lufttemperaturen und intensiver Sonneneinstrahlung, indirekt Zunahme von Feinstaub bei Hitze (〉30°C) und Ozonbelastung (〉200 Mikrogramm pro Kubikmeter) KATASTER-DETAIL:
    Keywords: Deutschland ; Umweltmedizin ; Luftverunreinigungen
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  • 39
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    In:  Kappas, M. (Hrsg): Klimawandel und Hautkrebs, Interdisziplinäre Projektgruppe CLIMAderm, Stuttgart, ibidem-Verlag, 1-11
    Publication Date: 2008
    Description: UV-Strahlungsbeeinflussende Faktoren Azimutwinkel, Bewölkung, Aerosole, stratosphärisches Ozon, biologische Wirkung in Abhängigkeit vom Hauttyp und Sensibilisierung (Jahreszeit) KATASTER-BESCHREIBUNG: Einfluss klimatischer Veränderungen auf die Häufigkeit von Hautkrebserkrankungen sehr wahrscheinlich, bei vermutlich hoher Bedeutung des (thermisch motivierten) Expositionsverhaltens KATASTER-DETAIL:
    Keywords: Deutschland ; Umweltmedizin ; UV-Strahlung
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  • 40
    Publication Date: 2008
    Description: zeitliche Trends und geografische Ursprünge der Vektor-übertragenen Krankheiten in Deutschland im Hinblick auf Stärken der bestehenden Krankheitsüberwachung für Hantavirus Infektion (endemisch in Deutschland), Chikungunya-Fieber (vor kurzem Schwellenländer in Europa) und Dengue-Fieber (importiert aus tropischen Regionen) KATASTER-BESCHREIBUNG: KATASTER-DETAIL:
    Keywords: Deutschland ; 2001-2007 ; Umweltmedizin ; Infektionskrankheiten
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  • 41
    Publication Date: 2008
    Description: Studie zu einer prognostizierten Anzahl von Tagen mit Wärme- und mit Kältestress, basierend auf Klimaszenarien für den Zeitraum 2071 bis 2100 KATASTER-BESCHREIBUNG: schätzungsweise durchschnittlicher Anstieg der Zahl der wärmeinduzierten Krankheitsfälle um einen Faktor von mehr als 3 und für hitzebedingte Krankenhausaufenthalte 6, Verlust von 0,1% bis 0.5% des BIP durch krankheitbedingten Arbeitsausfall KATASTER-DETAIL:
    Keywords: Deutschland ; Umweltmedizin
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  • 42
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    In:  In: Gostomzyk, J.G.; Enke, M. (Hrsg.): Globaler Klimawandel und Gesundheit. Schriftenreihe der Landeszentrale für Gesundheit in Bayern, Band 19, München, 2008, 75 – 85
    Publication Date: 2008
    Description: Pollensaison, -auftreten und -arten, sowie Veränderungen der Allergenität von Pollen unter Klimawandel KATASTER-BESCHREIBUNG: zunehmende Polysensibilisierungen gegenüber Inhalationsallergien durch zunehmend invasives Traubenkraut Ambrosia artemisiifolia KATASTER-DETAIL:
    Keywords: Deutschland ; Umweltmedizin ; Phänologie
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  • 43
    Publication Date: 2007
    Description: Studie zu einer prognostizierten Anzahl von Tagen mit Wärme- und mit Kältestress, basierend auf Klimaszenarien für den Zeitraum 2071 bis 2100 KATASTER-BESCHREIBUNG: Prognose: größere Zahl an Todesfällen durch Hitze im Süden gegenüber dem Norden Deutschlands und zugleich größerer Rückgang der Todesfälle durch Kälte im Norden, Anstieg der Todesopferzahl durch zunehmende Hitze insgesamt größer als Rückgang der Opferzahl durch weniger Kälte KATASTER-DETAIL:
    Keywords: Deutschland ; Umweltmedizin ; Temperatur
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  • 44
    Publication Date: 2006
    Keywords: Elementarschadenversicherung ; Natural disaster insurance ; Versicherungspflicht ; Mandatory insurance ; Katastrophenhilfe ; Emergency aid ; Marktversagen ; Market failure ; Überschwemmung ; Flood ; Theorie ; Theory ; Deutschland ; Germany ; Hochschulschrift ; Thesis ; Dissertation
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  • 45
    Publication Date: 2006
    Description: Autochthone Malaria in Deutschland, Historischer Abriss, Nachkriegsmalaria, Aktuelle malariaepidemiologische Situation KATASTER-BESCHREIBUNG: klimatische Bedingungen ermöglichen Ausreifung von Sporozoiten in heimischen Anophelesmücken, historisch erwiesen KATASTER-DETAIL:
    Keywords: Deutschland ; Umweltmedizin ; Infektionskrankheiten
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  • 46
    Publication Date: 2006
    Description: Herleitung einer Formel zur Berechnung der Plasmodium-Sporozoitenreifungszeit KATASTER-BESCHREIBUNG: Ausreifung von Pl. vivax- und Pl. falciparum-Sporozoiten im deutschen Raum möglich, Zustandekommen endemischer Malariaerregerübertragung bzw. Entstehung epidemiologisch wirksamer malariogener Potentiale dabei gebunden an das Vorhandensein von Gametozytenträgern und Überträgermücken KATASTER-DETAIL:
    Keywords: Deutschland ; Umweltmedizin ; Infektionskrankheiten
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  • 47
    Publication Date: 2005
    Keywords: Deutschland ; Umweltmedizin
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  • 48
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    In:  In: Klimastatusbericht 2003, DWD, Offenbach, 152-162
    Publication Date: 2003
    Keywords: Deutschland ; 2003 ; Umweltmedizin ; Temperatur
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  • 49
    Publication Date: 2003
    Description: Erfassung aller tatsächlichen oder vermuteten vektorassoziierten Krankheiten und Vektoren KATASTER-BESCHREIBUNG: viele Pathogene in Deutschland bereits vorhanden bzw. geeignete Vektoren stehen zur Verfügung, bei Einschleppung durch Reservoirwirte oder erkrankte Reisende sind autochthone Fälle zu erwarten KATASTER-DETAIL:
    Keywords: Deutschland ; Umweltmedizin ; Infektionskrankheiten
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  • 50
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    In:  Beiträge für Forstwirtschaft und Landschaftsökologie 2001(4): 4
    Publication Date: 2001
    Description: deutliche Verschiebungen der phänologischen Jahreszeiten, besonders der Frühjahrsphasen; für jede phänologische Phase negative und auch positive Trends entdeckt, z.T. auf engen Raum; Verschiebung auf Variation der Lufttemperatur zurückzuführen; Verlängerung der Vegetationsperiode, hauptsächlich durch Veränderungen im Frühjahr KATASTER-BESCHREIBUNG: KATASTER-DETAIL:
    Keywords: Deutschland ; 1951-1996
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  • 51
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    In:  International Journal of Biometeorology 42, 84-88
    Publication Date: 1998
    Description: Abnahme des thermischen Einflusses auf den saisonalen Verlauf der Mortalität KATASTER-BESCHREIBUNG: sich verbessernde Bedingungen im Gesundheitswesen und bei der Innenraumtemperatur bedingen Abnahme des thermischen Einflusses insb. für Mortalitätszunahme bei niedrigen Temperaturen KATASTER-DETAIL:
    Keywords: Deutschland ; 1946-1995 ; Umweltmedizin ; Temperatur
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  • 52
    Electronic Resource
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    Journal of Cellular Physiology 177 (1998), S. 377-386 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Apoptosis in cells of different lineages is restrained by survival signals which depend upon cell-to-cell communication. The aim of this study was to determine whether colonic cells deprived of crypt ambient are doomed to die prior to their normal chronological demise. Apoptosis was studied in rat whole colonic tissue, in isolated intact crypts, and in colonic cell populations collected from the crypt axis at different stages of proliferation and differentiation. In a number of experiments, cell harvest was performed in the presence of either a tetrapeptide (YVAD-CMK) inhibitor of interleukin-1β-converting enzyme (ICE), or tyrphostin A25, a protein tyrosine kinase inhibitor, or sodium-orthovanadate, a phosphatase inhibitor. DNA fragmentation was assessed by electrophoretic and nonisotopic-labeling procedures. The ultrastructure of colonic tissue specimens and isolated cells was examined by transmission electron microscopy. Apoptosis in whole colonic tissue and in isolated crypts was confined predominantly to cells resident in the upper crypt regions. In contrast, extensive apoptotic death was observed in isolated colonic cells, irrespective of their developmental stage and positional hierarchy within the crypt continuum at harvest time. An apoptotic gradient, however, was evident. Exposure to YVAD-CMK resulted in a marked decrease in the number of apoptotic cells. Treatment with tyrphostin A25 caused a sharp rise in the apoptotic index; conversely, vanadate significantly impeded apoptosis. Cumulatively, these results indicate that disordered intercellular communication provokes unscheduled ICE-mediated apoptosis of colonocytes, and that local signals along the crypt continuum control both the reprieve from death and the timely demise of distinct colonic cell populations. Attenuation of tyrosine phosphorylation may be a contributory event in the acquisition of the apoptotic phenotype. J. Cell. Physiol. 177:377-386, 1998. © 1998 Wiley-Liss, Inc.
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  • 53
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    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 177 (1998), S. 518-524 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: No abstract.
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  • 54
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    Journal of Cellular Physiology 177 (1998), S. 525-534 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: No abstract.
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  • 55
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    Journal of Cellular Physiology 177 (1998), S. 575-584 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The role of hsp27 as an inhibitor of actin polymerization was considered in the context of the actin cytoskeleton and its relationship with focal adhesion formation. The aim of this study was to evaluate the potential effects of hsp27 on focal adhesion formation as a relevant biological consequence of actin stress fiber formation. When hsp27 was overexpressed in stably transfected cells, cell attachment was delayed and recovery of disrupted stress fibers and focal adhesions was limited. In ROS 17/2.8 cells, heat shock caused the reversible disruption of stress fibers and focal adhesions. The loss of stress fibers and focal adhesions was associated with reduced phosphotyrosine on the focal adhesion kinase (FAK). Microinjection of recombinant 6-His hsp27 and phosphorylated 6-His hsp27 was used to demonstrate that nonphosphorylated hsp27 prevented the recovery of stress fibers and focal adhesions. These results provide in vivo evidence that hsp27 acts as an inhibitor of actin polymerization that can alter cellular interactions with extracellular environments by perturbation of stress fibers, and subsequently focal adhesions. J Cell Physiol 177:575-584, 1998. © 1998 Wiley-Liss, Inc.
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  • 56
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Hepatocytes entrapped in collagen gel and cultured in serum-free conditions survived longer than cells cultured on plastic (5 days vs. 3 weeks), showed fewer signs of early cell senescence (no increase in c-fos oncoprotein expression), and maintained the expression of differentiated hepatic metabolic functions over a longer period of time. Cells cultured in collagen gels retained their ability to respond to hormones. The insulin-stimulated glycogen synthesis rate remained fairly constant during 18 days in culture (between 5.4 ± 0.37 and 9 ± 2.7 nmol glucose/h/μg DNA). Collagen-cultured hepatocytes recovered glycogen stores to levels similar to those found in liver, or in hepatocytes isolated from fed rats. Urea synthesis from ammonia remained stable for more than 2 weeks (average value, 23 ± 4 nmol urea/h/μg DNA). The rate of albumin synthesis in collagen-entrapped cells was maintained above the day-1 level during 18 days in culture. Cells showed high levels of glutathione (GSH) (1,278 ± 152 pmol/μg DNA). Biotransformation activities CYP4501A1, CYP4502A2, CYP4502B1, and CYP4503A1 remained fairly stable in collagen-cultured hepatocytes. CYP4502E1 and CYP4502C11 decreased but were still measurable after 18 days. After 4 days in culture, GST activity returned to levels observed in isolated hepatocytes. In contrast with plastic cultures, cells responded to CYP450 inducers (methylcholanthrene for CYP4501A1, CYP4501A2, and gluthatione-transferase, and ethanol for CYP4502E1) for more than 2 weeks. CYP4501A1, CYP4501A2, and glutathione-transferase A2 (GST A2) induction was preceded by an increase in specific mRNA, while the effects on CYP4502E1 seemed to be at a posttranslational level. Analysis of the expression of relevant hepatic genes by reverse Northern and semiquantitative reverse transcriptase-polymerase chain reaction (RT-PCR) revealed that culturing hepatocytes in collagen gels results in a sustained higher expression of key liver transcription factor genes DBP, C/EBP-α and -β, and HNF-1 and -4, as well as specific liver enzyme genes (phosphoenol pyryvate carboxykinase, and carbamoylphosphate-synthetase I). J Cell Physiol 177:553-562, 1998. © 1998 Wiley-Liss, Inc.
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  • 57
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    Journal of Cellular Physiology 177 (1998), S. 535-552 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The viral Crk oncogene (v-Crk) is known to induce sarcomas in chicken and its cellular homologs c-Crk I, c-Crk II, and Crk-like (CRKL) have been implicated in many signal transduction events. These include cell differentiation, cell migration, and the induced nonresponsiveness of T-cells to stimulation of the T-cell receptor (TCR), a state known as anergy. CRKL is also the most prominent substrate of the Bcr-Abl oncoprotein which causes human chronic myelogenous leukemias (CML). The modular composition of the Crk family adapters which largely consist of Src homology (SH2 and SH3) domains has prompted an intensive search for physiological and pathological upstream and downstream signalling partners which selectively bind to these adapters. Upstream proteins include various receptors and large multisite docking proteins, while several protein kinases and guanine nucleotide release proteins (GNRPs) have been suggested to function downstream of c-Crk and CRKL. Most Crk/CRKL SH2- and SH3-binding proteins contain several docking sites with considerable sequence similarity. Thus the binding requirements of Crk/CRKL SH2 and SH3 domains are now well defined, providing a basis for the design of small inhibitory molecules to block the function of these adapter proteins. The enzymatic cascades activated through Crk family adapters are only partially known, but stress kinases (SAPKs/JNKs) and the GTPase Rap1, as well as the B-Raf isoform of the Raf protein kinases, are affected in some systems. Several yet unidentified, highly selective Crk interacting proteins detectable in specific cell types remain to be studied. More detailed analyses of the enzymatic activities triggered through Crk-type adapters will also be crucial to fully define the signalling pathways controlled by this protein family. J Cell Physiol 177:535-552, 1998. © 1998 Wiley-Liss, Inc.
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  • 58
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: We have previously described a specific, saturable receptor for rat collagenase-3 in the rat osteosarcoma cell line, UMR 106-01. Binding of rat collagenase-3 to this receptor is coupled to the internalization and eventual degradation of the enzyme and correlates with observed extracellular levels of the enzyme. In this study we have shown that decreased binding, internalization, and degradation of 125I-rat collagenase-3 were observed in cells after 24 h of parathyroid hormone treatment; these activities returned to control values after 48 h and were increased substantially (twice control levels) after 96 h of treatment with the hormone. Subcellular fractionation studies to identify the route of uptake and degradation of collagenase-3 localized intracellular accumulation of 125I-rat collagenase-3 initially in Golgi-associated lysosomes and later in secondary lysosomes. Maximal lysosomal accumulation of the radiolabel and stimulation of general lysosomal activity occurred after 72 h of parathyroid hormone treatment. Preventing fusion of endosomes with lysosomes (by temperature shift, colchicine, or monensin) resulted in no internalized 125I-collagenase-3 in either lysosomal fraction. Treatment of UMR cells with the above agents or ammonium chloride decreased excretion of 125I-labeled degradation products of collagenase-3. These experiments demonstrated that degradation of collagenase-3 required receptor-mediated endocytosis and sequential processing by endosomes and lysosomes. Thus, parathyroid hormone regulates the expression and synthesis of collagenase-3 as well as the abundance and functioning of the collagenase-3 receptor and the intracellular degradation of its ligand. The coordinate changes in the secretion of collagenase-3 and expression of the receptor determine the net abundance of the enzyme in the extracellular space. J Cell Physiol 177:563-574, 1998. © 1998 Wiley-Liss, Inc.
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  • 59
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    Journal of Cellular Physiology 177 (1998), S. 585-592 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The effect of metabolic inhibitors on nontransferrin bound iron transport by K562 cells was investigated. Incubation with 1 μM rotenone, 10 μM antimycin, or 0.5 mM 2,4-dinitrophenol effectively reduced ATP levels by ∼50%. Both the rate and extent of Fe+3 uptake were impaired in ATP-depleted cells, which display a reduced Vmax for uptake. K562 cell ferrireductase activity was also lowered by metabolic inhibitors, suggesting that the apparent energy requirements for transport reside in the reduction of Fe+3 to Fe+2. However, ATP depletion was found to inhibit the rate and extent of Fe+2 uptake as well. Thus, the transbilayer passage of Fe+2 and/or Fe+3 appears to be an energy-requiring process. These features possibly reflect properties of the transport mechanism associated with a recently identified K562 cell transport protein, called SFT for “Stimulator of Fe Transport,” since exogenous expression of its activity is also affected by ATP depletion. J Cell Physiol 177:585-592, 1998. © 1998 Wiley-Liss, Inc.
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  • 60
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    Journal of Cellular Physiology 177 (1998), S. 593-605 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Clusterin (ApoJ) is an extracellular glycoprotein expressed during processes of tissue differentiation and regression that involve programmed cell death (apoptosis). Increased clusterin expression has also been found in tumors, however, the mechanism underlying this induction is not known. Apoptotic processes in tumors could be responsible for clusterin gene activation. Alternatively, oncogenic mutations could modulate signal transduction, thereby inducing the gene. We examined the response of the rat clusterin gene to two oncogenes, Ha-ras and c-myc, in transfected Rat1 fibroblasts. While c-myc overexpression did not modify clusterin gene activity, the Ha-ras oncogene produced a seven to tenfold repression of clusterin mRNA; this down-regulation was also observed in the presence of c-myc. Since no induction of the clusterin gene was observed by the two oncogenes, we tested the alternative mechanism involving apoptosis. Growth factor withdrawal induced apoptosis, as shown by DNA degradation and micronuclei formation in the floating cells. Concomittantly we observed a three to tenfold increase in the amount of clusterin mRNA in the adhering cells of Rat1 and the c-myc transformed cell lines, and a weaker induction in the Ha-ras transformed cell line. On the basis of our results, we suggest that clusterin gene induction in the vital cells is produced by signaling molecules that are generated by the apoptotic cells. We conclude that apoptotic processes, not oncogenic mutations, are responsible for increased clusterin expression in tumors. J Cell Physiol 177:593-605, 1998. © 1998 Wiley-Liss, Inc.
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  • 61
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    Journal of Cellular Physiology 177 (1998), S. 618-627 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: We previously reported that the enterocytic differentiation of human colonic Caco-2 cells correlated with down-regulation of fibronectin (FN) and laminin (LN), two extracellular matrix components interacting with cell surface integrin receptors. We now investigated whether Caco-2 cell differentiation was associated with alterations in integrin signaling with special interest in the expression and activity of focal adhesion kinase (FAK) and mitogen-activated protein (MAP) kinase. The differentiation of Caco-2 cells was associated with: (1) down-regulation of β1 integrin expression at the mRNA and protein levels; (2) increased FAK expression together with decreased FAK autophosphorylation; (3) decreased FAK's ability to associate with PI3-kinase and pp60c-src; and (4) increased MAP kinase expression along with decreased MAP activity. In addition, we show that FAK and MAP kinase belong to distinct integrin signaling pathways and that both pathways remain functional during Caco-2 cell differentiation since the coating of differentiating cells on FN and LN but not on polylysine increased the tyrosine phosphorylation of FAK and of its endogenous substrate paxillin, and stimulated MAP kinase activity. In conclusion, our results provide evidence that FAK and MAP kinase, two signaling molecules activated independently by β1 integrins in Caco-2 cells, undergo alterations of both expression and activity during the enterocytic differentiation of this cell line. J Cell Physiol 177:618-627, 1998. © 1998 Wiley-Liss, Inc.
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  • 62
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Salivary glands contain two major epithelial cell types: acinar cells which produce the primary salivary secretion, including amylase, and ductal cells which reabsorb electrolytes but also secrete kallikrein. Here we investigated salivary acinar cell differentiation in vitro using the activity of the salivary amylase and tissue kallikrein promoters as markers of acinar cell and ductal cell differentiation, respectively. Each of the promoter sequences was cloned into a replication-deficient adenoviral vector containing the luciferase reporter gene. Previous studies showed that a human submandibular gland cell line (HSG) differentiated into acinar cells when cultured on a reconstituted basement membrane matrix (Matrigel). The luciferase activity of the amylase promoter vector (AdAMY-luc) was low in HSG cells cultured on plastic, where they grow as an epithelial monolayer. The promoter activity increased approximately tenfold when HSG cells were cultured on Matrigel and developed an acinar phenotype. Under the same conditions, the luciferase activity of the kallikrein promoter (AdKALL-luc) was not induced. Because HSG cells demonstrate acinar cell morphology, but not amylase gene expression, when cultured on laminin-1, certain soluble components of Matrigel were tested for their ability to induce the amylase promoter during in vitro differentiation of acinar cells. We find that epidermal growth factor (EGF) and transforming growth factor-alpha (TGF-α), which are present in the basement membrane, and hepatocyte growth factor (HGF) increase activity of the amylase promoter. Other basement membrane-derived growth factors such as TGF-β, basic fibroblast growth factor (bFGF), and platelet-derived growth factor (PGDF), as well as tumor necrosis factor (TNF-α), keratinocyte growth factor (KGH), nerve growth factor (NGF) and interferon gamma (IFN-γ) were inactive. This system will be further exploited to study the mechanisms by which extracellular matrix molecules and growth factors regulate salivary acinar cell differentiation. J Cell Physiol 177:628-635, 1998. Published 1998 Wiley-Liss, Inc.
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  • 63
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The role of HSP27 in cell growth and resistance to stress was investigated using murine fibrosarcoma L929 cells (normally devoid of constitutively expressed small HSPs) and human osteoblast-like SaOS-2 cells stably transfected with a human hsp27 expression vector. Our data showed that our L929 cells were more resistant to oxidative stress than generally observed for this line. Production of HSP27 in these cells led to a marked decrease in growth rate associated with a series of phenotypical changes, including cell spreading, cellular and nuclear hypertrophy, development of an irregular outline, and a tremendous accumulation of actin stress fibers. By contrast, none of these changes was observable in SaOS-2/hsp27 transfectants overexpressing the protein product. Together, these observations are consistent with a cause-to-effect cascade relationship between increased (or induced) HSP27 expression, changes in cytoskeletal organization, and decreased growth. On the other hand, whereas the transfection of the hsp27 gene increased the cell resistance to heat in both cell lines, only in SaOS-2 cells was this associated with protection to the cytotoxic action of tumor necrosis factor-alpha (TNF-α) and etoposide. Unexpectedly, L929/hsp27 transfectants exhibited an increased sensitivity to both agents and also to H2O2. These data thus imply that different mechanisms are involved in the cell resistance to heat shock and to the cytotoxic action of TNF-α, etoposide, and H2O2. They also plead against the simple view that overexpression of a phosphorylatable HSP27 would necessarily be beneficial in terms of increased cell resistance to any type of stress. Our data further indicate that the role of HSP27 in cellular resistance to stress and in cell proliferation involves different targets and that the ultimate result of its interference with these processes depends on the intracellular context in which the protein is expressed. J Cell Physiol 177:606-617, 1998. © 1998 Wiley-Liss, Inc.
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  • 64
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Using an expression cloning approach, we identified and cloned a novel intracellular protein produced by osteoclasts that indirectly induces osteoclast formation and bone resorption, termed OSF. Conditioned media from 293 cells transiently transfected with the 0.9 kb OSF cDNA clone stimulated osteoclast-like cell formation in both human and murine marrow cultures in the presence or absence 10-9 M 1,25-dihydroxyvitamin D3. In addition, conditioned media from 293 cells transfected with the OSF cDNA clone enhanced the stimulatory effects of 1,25-(OH)2D3 on bone resorption in the fetal rat long bone assay. In situ hybridization studies using antisense oligomers showed expression of OSF mRNA in highly purified osteoclast-like cells from human giant cell tumors of the bone. Northern blot analysis demonstrated ubiquitous expression of a 1.3 kb mRNA that encodes OSF in multiple human tissues. Sequence analysis showed the OSF cDNA encoded a 28 kD peptide that contains a c-Src homology 3 domain (SH3) and ankyrin repeats, suggesting that it was not a secreted protein, but that it was potentially involved in cell signaling. Consistent with these data, immunoblot analysis using rabbit antisera against recombinant OSF demonstrated OSF expression in cell lysates but not in the culture media. Furthermore, recombinant OSF had a high affinity for c-Src, an important regulator of osteoclast activity. Taken together, these data suggest that OSF is a novel intracellular protein that indirectly enhances osteoclast formation and osteoclastic bone resorption through the cellular signal transduction cascade, possibly through its interactions with c-Src or other Src-related proteins. J Cell Physiol 177:636-645, 1998. © 1998 Wiley-Liss, Inc.
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  • 65
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The addition of dexamethasone (dex) to human fibroblast cultures has been found to elicit enhanced proliferation. This enhancement is manifested by an increase in the initial growth rate, saturation density, and proliferative life span of WI-38 fibroblast cultures grown in the presence of dex. We examined the acute effects of dex on a number of growth-related genes in WI-38 cells. Our results show a decrease in the level of the cyclin-dependent kinase inhibitor p21Waf1/Cip1/Sdi1 in response to dex. In addition, the level of the insulin-like growth factor type 1 receptor (IGF-1R) is increased in dex-treated cells. These changes are correlated with changes in the activity of the p21Waf1/Cip1/Sdi1 and IGF-1R promoters. The results presented in this report suggest that dex may delay growth arrest in response to contact inhibition, as well as during cellular senescence. Thus, dex may act at multiple levels to enhance cellular proliferation in WI-38 cells: first, to decrease the level of an inhibitor of cell-cycle progression, and second, to increase the sensitivity of WI-38 cells to the proliferative effects of IGF-1. These acute effects may cooperate with other, as yet uncharacterized effects, to result in the enhanced proliferation seen in the presence of dex. J. Cell. Physiol. 177:396-401, 1998. © 1998 Wiley-Liss, Inc.
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  • 66
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    Journal of Cellular Physiology 177 (1998), S. 402-410 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Potassium (K+) conductances are known to be involved in cell proliferation of a number of nonexcitable cell types. The nature of the mechanism by which K+ channel inhibition reduces cell proliferation has remained elusive despite intensive search. We investigated whether such a phenomenon could be demonstrated in excitable cells, using the GH3 pituitary cell line as a cell model. Our aims were: (1) to study the effect of K+ channel inhibition on the proliferation of GH3 cells; and (2) to investigate the putative intracellular signals involved in this inhibition. Tetraethylammonium chloride (TEA), a blocker of the calcium (Ca2+)-dependent K+ conductances of GH3, was found to reversibly inhibit cell proliferation, as measured by 3H-thymidine incorporation. Cell cycle block specifically occurred at the G1/S phase of the cell cycle. This inhibition of proliferation was observed for 1-4 mM TEA, which suppressed most of the Ca2+-activated K+ current and part of the inward rectifying K+ current, as shown by electrophysiological experiments. Increasing extracellular K+ concentrations with KCl also inhibited cell proliferation in a dose-dependent manner. Both TEA and KCl depolarized the cells and increased intracellular Ca2+ levels ([Ca2+]i), showing that, in this type of excitable cell, inhibition of cell proliferation can be associated with elevated Ca2+ levels. Ca2+ and membrane resting potential (MRP) were considered as possible messengers of this inhibition. Our results suggest that cell cycle arrest of GH3 cells by K+ channel block probably involves an additional pathway, distinct from those of Ca2+ and MRP. J. Cell. Physiol. 177:402-410, 1998. © 1998 Wiley-Liss, Inc.
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  • 67
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    Journal of Cellular Physiology 177 (1998), S. 387-395 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Previously, we reported that unaggressive, growth factor-dependent FET human colon carcinoma cells downregulated their transforming growth factor alpha (TGFα) expression in a quiescent state (G0/G1) induced by growth factor and nutrient deprivation (Mulder, 1991, Cancer Res., 51:2256-2262). In contrast, highly aggressive, growth factor-independent HCT116 human colon carcinoma cells aberrantly upregulated this autocrine activity in the quiescent state (Mulder, 1991, Cancer Res., 51:2256-2262; Howell et al., 1998, Mol. Cell. Biol., 18:303-313). In this report, the role of autocrine TGFα and the mechanism of its regulation of expression during reentry into the cell cycle from a noncycling growth state were determined in FET cells. Optimal induction of DNA synthesis from a quiescent state in FET cells is dependent upon autocrine TGFα as well as exogenous transferrin and insulin. Reentry into the cell cycle resulting from treatment with exogenous transferrin and insulin resulted in ∼3-fold induction of TGFα expression within 1 hr. TGFα induction was controlled at the transcription level, and the cis-controlling element was localized to the region between bp -370--201 relative to the translation start codon within the TGFα promoter. Thus neutralization of autocrine TGFα protein revealed that the induced TGFα autocrine activity was necessary for DNA synthesis and acted only in the early G1 phase of the cell cycle. Blockade of autocrine TGFα expression early in the cell cycle resulted in the reduction of DNA synthesis, whereas treatment with neutralization antibody at later times had no effect. This suggested that autocrine TGFα functions to initiate cell growth from noncycling states. This was further confirmed by the dependence of FET cells upon autocrine TGFα for colony formation in experiments where the plating density was sufficiently low to generate a lag phase in tissue culture. In contrast, TGFα autocrine activity was not required for exponential phase cells, as evidenced by the failure of TGFα neutralizing antibody to inhibit proliferation in this growth state. Taken together, these results suggest that autocrine TGFα acts primarily in the process of growth initiation by moving cells from a noncycling state back into the cell cycle, rather than supporting cell growth already initiated. J. Cell. Physiol. 177:387-395, 1998. © 1998 Wiley-Liss, Inc.
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  • 68
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Basic fibroblast growth factor (bFGF, FGF-2) is progressively lost from mammary epithelial cells as they become malignant. To investigate the effects of restoring the expression of bFGF in breast cancer cells, we constructed MCF-7 cells that permanently overexpress 18-kD cytoplasm-localizing bFGF (MCF-7/ΔAFGF(18) cells) and cells that express both the 18-kD along with the 22- and 24-kD nucleus-localizing bFGF peptides (MCF-7/NCFFGF(18,22,24) cells), using retroviral transduction. These stable cell constructs grew more slowly and had a larger fraction of their populations in the G0/G1 phase of the cell cycle than control cells. All forms of bFGF were eluted from MCF-7/NCFFGF(18,22,24) cell monolayers with 2 M NaCl, in contrast to fibroblasts that were demonstrated to secrete only the 18-kD bFGF isoform. High-affinity binding of 18-kD 125I-bFGF to these cells was significantly decreased, probably because of competitive binding by the autocrine-secreted bFGF. Recombinant 18-kD bFGF that was previously demonstrated in our laboratory to inhibit proliferation, activate MAP kinase, and induce the cyclin-dependent kinase inhibitor p21WAF1/CIP1 in MCF-7 cells, further inhibited MCF-7/ΔAFGF(18) cells but had no effect on MCF-7/NCFFGF(18,22,24) cells. The total cellular content of the high-affinity FGF receptors 1-3 was unchanged, but FGF receptor 4 was decreased in MCF-7/NCFFGF(18,22,24) cells. Both cell types overexpressing bFGF isoforms had elevated levels of the cyclin-dependent kinase inhibitor p27Kip1 but not that of p21WAF1/CIP1. In MCF-7/ΔAFGF(18) cells, FGFR1 and MAP kinase were constitutively phosphorylated. Exogenous recombinant 18-kD bFGF did not accentuate these effects but did induce an increase in the levels of p21WAF1/CIP1 corresponding to the further inhibition induced by exogenous bFGF in these cells. In MCF-7/NCFFGF(18,22,24) cells, FGFR1 and MAP kinase were not phosphorylated at baseline nor upon stimulation with recombinant bFGF, and exogenous bFGF only had a minimal effect on low steady-state p21WAF1/CIP1 levels. However, stimulation of these cells with phorbol ester or insulin did result in MAP kinase phosphorylation. While growth-inhibited in the G1 phase of the cell cycle, MCF-7/NCFFGF(18,22,24) cells retained active isoforms of cdk2 and the hyperphosphorylated form of Rb. These data suggest that high molecular weight forms of bFGF overexpressed in MCF-7 cells do not activate the receptor-mediated MAP kinase pathway, and do not induce p21WAF1/CIP1 in an autocrine manner, but inhibit proliferation through other, possibly direct nuclear signalling mechanisms. J. Cell. Physiol. 177:411-425, 1998. © 1998 Wiley-Liss, Inc.
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  • 69
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Bone marrow stromal cells (BMSCs) are a heterogeneous population of cells derived from colony-forming units-fibroblastic (CFU-Fs). These cells reside in the bone marrow cavity and are capable of differentiating into several cell phenotypes including osteoblasts, chondroblasts, hematopoiesis-supporting stromal cells, and adipocytes. However, the factors that regulate the proliferation and differentiation of the BMSC population are for the most part unknown. Since many members of the receptor tyrosine kinase (RTK) family have been shown to participate in growth control of various mesenchymal cell populations, in this study we examined the expression and function of RTKs in the BMSC population. Degenerate oligonucleotides corresponding to two conserved catalytic domains of the RTK family and RT-PCR were used initially to determine which RTKs are expressed in the human BMSC (hBMSC) system. After subcloning the amplification product generated from mRNA of a multicolony-derived hBMSC strain, PDGF receptor (β), EGF receptor, FGF receptor 1, and Axl were identified by DNA sequencing of 26 bacterial colonies. Furthermore, PDGF and EGF were found to enhance BMSC growth in a dose-dependent manner and to induce tyrosine phosphorylation of intracellular molecules, including the PDGF and EGF receptors themselves, demonstrating the functionality of these receptors. On the other hand, bFGF was found to have little effect on proliferation or tyrosine phosphorylation. Since single colony-derived hBMSC strains are known to vary from one colony to another in colony habit (growth rate and colony structure) and the ability to form bone in vivo, the expression levels of these RTKs were determined in 18 hBMSC clonal strains by semiquantitative RT-PCR and were found to vary from one clonal strain to another. While not absolutely predictive of the osteogenic capacity of individual clonal strains, on average, relatively high levels of PDGF-receptor were found in bone-forming strains, while on average, nonbone-forming strains had relatively high levels of EGF-receptor. Taken together, these results indicate that RTKs play a role in the control of hBMSC proliferation, and that the differential pattern of RTK expression may be useful in correlating the biochemical properties of individual clonal strains with their ability to produce bone in vivo. J. Cell. Physiol. 177:426-438, 1998. © 1998 Wiley-Liss, Inc.
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  • 70
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Vascular endothelial growth factor-C (VEGF-C) is a recently characterized member of the VEGF family of angiogenic polypeptides. We demonstrate here that VEGF-C is angiogenic in vitro when added to bovine aortic or lymphatic endothelial (BAE and BLE) cells but has little or no effect on bovine microvascular endothelial (BME) cells. As reported previously for VEGF, VEGF-C and basic fibroblast growth factor (bFGF) induced a synergistic in vitro angiogenic response in all three cells lines. Unexpectedly, VEGF and VEGF-C also synergized in the in vitro angiogenic response when assessed on BAE cells. Characterization of VEGF receptor (VEGFR) expression revealed that BME, BAE, and BLE cell lines express VEGFR-1 and -2, whereas of the three cell lines assessed, only BAE cells express VEGFR-3. We also demonstrate that VEGF-C increases plasminogen activator (PA) activity in the three bovine endothelial cell lines and that this is accompanied by a concomitant increase in PA inhibitor-1. Addition of α2-antiplasmin to BME cells co-treated with bFGF and VEGF-C partially inhibited collagen gel invasion. These results demonstrate, first, that by acting in concert with bFGF or VEGF, VEGF-C has a potent synergistic effect on the induction of angiogenesis in vitro and, second, that like VEGF and bFGF, VEGF-C is capable of altering endothelial cell extracellular proteolytic activity. These observations also highlight the notion of context, i.e., that the activity of an angiogenesis-regulating cytokine depends on the presence and concentration of other cytokines in the pericellular environment of the responding endothelial cell. J. Cell. Physiol. 177:439-452, 1998. © 1998 Wiley-Liss, Inc.
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  • 71
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Cell cycle control of histone H4 gene transcription is mediated by the multipartite promoter domain H4-Site II, which supports transcriptional activation at the G1/S phase transition and modulates basal H4 gene transcription. Proliferation-specific transcription is determined by the integrated activities of three distinct promoter factors interacting with H4-Site II: the interferon regulatory factor IRF-2 (synonymous with HiNF-M), HiNF-D (a complex between the homeodomain protein CDP-cut and the cell cycle mediators CDC2, cyclin A and pRB), as well as HiNF-P/H4TF-2. However, the contribution of HiNF-D to the enhancement and/or suppression of H4 gene transcription at specific cell cycle stages remains to be established. We used a panel of synchronized HeLa S3 cell lines containing stably integrated H4 promoter/CAT reporter gene constructs with mutations in H4-Site II. The temporal regulation of CAT mRNA accumulation under the control of the H4 promoter was analyzed by RNase protection analysis. Our main finding is that mutation of the HiNF-D/CDP-cut binding site alters the timing of histone gene activation during the cell cycle. Furthermore, our data indicate that HiNF-P/H4TF-2 may functionally compensate for HiNF-M/IRF-2 at Site II to regulate histone H4 gene transcription in HeLa S3 cervical carcinoma cells during early S phase. We postulate that HiNF-D (CDP-cut/cyclin A/CDC2/pRB containing complex) promotes HiNF-M/IRF-2 (and/or HiNF-P/H4TF-2) dependent histone H4 gene activation at the G1/S phase transition and attenuates H4 gene transcription at later cell cycle stages. The mechanistic division in the gene regulatory functions of the three H4-Site II binding proteins may ensure that histone H4 gene expression is stringently coupled with the onset of S phase in response to growth factor/cytokine-induced cell cycle progression. J. Cell. Physiol. 177:453-464, 1998. © 1998 Wiley-Liss, Inc.
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  • 72
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    Journal of Cellular Physiology 177 (1998), S. 465-473 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Human dermal fibroblasts suspended in a collagen matrix exhibit a 4-day delay in cell division, while the same cells in monolayer divided by day 1. The initial rates of 3H-thymidine incorporation by cells in monolayer or suspended in collagen were not significantly different. When suspended in collagen, there was a threefold increase in the proportion of cells in a tetraploidal (4N) DNA state compared to the same cells in monolayer. Flow cytometry analysis and 3H-thymidine incorporation studies identified the delay of cell division as a consequence of a block in the G2/M of the cell cycle and not an inhibition of DNA synthesis. The inclusion of 150 μ/ml of hyaluronic acid (HA) in the manufacture of fibroblast populated collagen lattices (FPCL) caused a stimulation of cell division, as determined by cell counting; increased the expression of tubulin, as determined by Western blot analysis; and reduced the proportion of cells in a 4N state, as determined by flow cytometry. HA added to the same cells growing in monolayer produced a minimal increase in the rate of cell division or DNA synthesis. HA supplementation of FPCLs stimulated cell division as well as tubulin concentrations, but it did not enhance lattice contraction. The introduction of tubulin isolated from pig brain or purchased tubulin into fibroblasts by electroporation prior to their transfer into collagen lattices promoted cell division in the first 24 hours and enhanced FPCL contraction. It is proposed that tubulin protein, the building blocks of microtubules, is limited in human fibroblasts residing within a collagen matrix. When human fibroblasts are suspended in collagen, one effect of added HA may be to stimulate the synthesis of tubulin which assists cells through the cell cycle. J. Cell. Physiol. 177:465-473, 1998. © 1998 Wiley-Liss, Inc.
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  • 73
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    Journal of Cellular Physiology 177 (1998), S. 474-482 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: In this study we examined the regulation of cdk1 expression in normal human epidermal keratinocytes (HEKs) and neoplastic keratinocytes. Keratinocytes were growth-arrested by allowing the cells to grow to confluence or by treating them with interferon-gamma (IFNγ) or 12-O-tetradecanoyl phorbol-13-acetate (TPA). RT-PCR and Western blot analysis demonstrated that cdk1 was profoundly reduced in growth-arrested HEKs when compared with dividing HEKs. In contrast, a squamous carcinoma cell line, SCC25, did not growth-arrest in response to growth inhibitors and did not downregulate cdk1 expression. Transfection of HEKs with a reporter gene driven off a 2.5-kb fragment of the human cdk1 promoter indicated that the downregulation of cdk1 upon growth arrest was transcriptional. Deletion mapping of the cdk1 promoter indicated that a repressor region was located between -949--722 bp. This repressor region was not operative in the SCC25 cells. Examination of DNA:protein binding complexes by gel-shift analysis indicated that nuclear factors from both proliferative and growth-arrested cells bound to the DNA fragment spanning -949--722 bp. Further analysis revealed that this binding could be resolved into a constitutive and growth arrest-specific complex that bound in a similar fashion to regions spanning -892--831 bp and -831--774 bp, respectively. The putative growth arrest-specific complex was not found in contact-inhibited fibroblasts and was found at very low levels in SCC25 cells, indicating that the putative repressor binding was growth arrest-specific and possibly keratinocyte-specific. The binding complexes bound to these two fragments were localized, by competition analysis, to regions -874--853 bp and -830--800 bp. This is the first report of a transcriptional repressor being operative during keratinocyte growth arrest. J. Cell. Physiol. 177:474-482, 1998. © 1998 Wiley-Liss, Inc.
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  • 74
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    Journal of Cellular Physiology 177 (1998), S. 483-492 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Treatment with the sulfhydryl oxidant diamide denatures and aggregates cellular proteins, which prior studies have implicated as an oxidative damage that activates the heat shock transcription factor and induces thermotolerance. This study was initiated to further characterize cellular response to diamide-denatured proteins, including their involvement in diamide cytotoxicity. Cytotoxic diamide exposures at 37.0°C denatured and aggregated cellular proteins in a manner that was proportional to cell killing, but this correlation was different than that established for heated cells. Diamide exposures at 24.0°C were orders of magnitude less cytotoxic, with little additional killing occurring after diamide was removed and cells were returned to 37.0°C. Thus, protein denaturation that occurred at 37.0°C, after proteins were chemically destabilized by diamide at 24.0°C [Freeman et al., J. Cell. Physiol., 164:356-366 (1995) Senisterra et al., Biochemistry 36: 11002-11011 (1997)], had little effect on cell killing. Thermotolerance protected cells against diamide cytotoxicity but did not reduce the amount of denatured and aggregated protein observed immediately following diamide exposure. However, denatured/aggregated proteins in thermotolerant cells were disaggregated within 17 h following diamide exposure, while no disaggregation was observed in nontolerant cells. This more rapid disaggregation of proteins may be one mechanism by which thermotolerance protects cells against diamide toxicity, as it has been postulated to do against heat killing. As with heat shock, nontoxic diamide exposures induced maximal tolerance against heat killing; however, there was no detectable, increased synthesis of heat shock proteins. Thus, diamide treatment proved to be a reproducible procedure for inducing a phase of thermotolerance that does not require new heat shock protein (HSP) synthesis, without having to use transcription or translation inhibitors to suppress HSP gene expression.These results complement those from studies with other stresses to establish the importance of protein denaturation/aggregation as a cytotoxic consequence of stress and a trigger for thermotolerance induction. The data also illustrate that differences in how proteins are denatured and aggregated can affect their cytotoxicity and the manner in which thermotolerance is expressed. J. Cell. Physiol. 177:483-492, 1998. © 1998 Wiley-Liss, Inc.
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  • 75
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    Journal of Cellular Physiology 177 (1998), S. 499-499 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: No abstract.
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  • 76
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    Journal of Cellular Physiology 177 (1998), S. 501-506 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: CDK9 is a cdc2-related kinase protein. Previously named PITALRE, this protein is a serine-threonine kinase involved in many physiological processes. Unlike most of the cdc2-like kinases, its activity is not cell cycle-regulated. CDK9 acts preferentially in processes different from cell-cycle regulation, such as differentiation. Its cyclin partners, cyclins of T family, recently have been isolated. CDK9 immunoprecipitates with several unidentified polypeptides that may regulate its kinase activity. CDK9 has been shown to associate with the HIV-Tat protein, suggesting a possible involvement in AIDS. CDK9 recently was shown to be responsible for the kinase activity associated with the TAK complex and with the P-TEFb complex, suggesting activity also in the transcription process. J Cell Physiol 177:501-506, 1998. © 1998 Wiley-Liss, Inc.
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  • 77
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    Journal of Cellular Physiology 177 (1998), S. 493-498 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Ultraviolet light A (UVA) is shown to play an augmentative or synergistic role with UVB in pathophysiological conditions induced by solar radiation. Thus, UVA would contribute significantly to the development of skin malignancies. It remains unclear, however, how UVA contributes to solar radiation-induced immune suppression. Keratinocytes (KC) produce cytokines which are a significant mediator of inflammatory and immunologic reactions in skin exposed to solar radiation and are a potent mediator in the induction of immune suppression. To examine if UVA alters the expression and production of cytokines from KC, normal human keratinocytes (HuSK) were cultured and exposed to UVA at doses ranging between 2.5 and 20 kJ/m2. Constitutive expression of the p35 subunit of interleukin (IL)-12 was detected by reverse transcription-polymerase chain reaction (RT-PCR) and the p40 subunit was induced by UVA irradiation dose dependently. IL-12 protein was also detected in the supernatants from UVA-irradiated HuSK by enzyme-linked imuunosorbent assay (ELISA) and confirmed by a bioassay. On the other hand, the same doses of UVA did not induce IL-10 mRNA or IL-10 protein which has been shown to be one of the cytokines responsible for the induction of UVB-induced immunosuppression. Considering that IL-12 promotes activation of Th1 cells and prevents the activation of Th2 cells and that administration of IL-12 has been shown to block the induction of immune suppression in UV-irradiated animals, our results suggest that UVA modulates skin immune function distinctively from UVB by affecting the balance between IL-10 and IL-12 produced from KC. J. Cell. Physiol. 177:493-498, 1998. © 1998 Wiley-Liss, Inc.
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  • 78
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    Journal of Cellular Physiology 177 (1998), S. 507-517 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Neuropeptides, including mammalian bombesin-like peptides, act as potent cellular growth factors and have been implicated in a variety of normal and abnormal processes, including development, inflammation, and malignant transformation. These signaling peptides exert their characteristic effects on cellular processes by binding to specific G protein-coupled receptors (GPCR) on the surface of their target cells. Typically, the binding of a neuropeptide to its cognate GPCR triggers the activation of multiple signal transduction pathways that act in a synergistic and combinatorial fashion to relay the mitogenic signal to the nucleus and promote cell proliferation. A rapid increase in the synthesis of lipid-derived second messengers with subsequent activation of protein phosphorylation cascades is an important early response to neuropeptides. An emerging theme in signal transduction is that these agonists also induce rapid and coordinate tyrosine phosphorylation of cellular proteins including the nonreceptor tyrosine kinase p125fak and the adaptor proteins p130cas and paxillin. This tyrosine phosphorylation pathway depends on the integrity of the actin cytoskeleton and requires functional Rho. The purpose of this article is to review recent advances in unraveling the pathways that play a role in transducing mitogenic and migratory responses induced by G protein-coupled neuropeptide receptor agonists. J Cell Physiol 177:507-517, 1998. © 1998 Wiley-Liss, Inc.
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  • 79
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: The pentameric B subunit of verotoxin (VT) mediates the attachment to cell surface globotriaosyl ceramide (Gb3) to facilitate receptor-mediated endocytosis of the toxin. In highly toxin-sensitive tumor cells, the holotoxin and VT1 B subunit is targeted intracellularly to elements of the endoplasmic reticulum (ER)/nuclear membrane. In less sensitive cells, the toxin is targeted to components of the Golgi apparatus. We have studied two cell systems: the induced VT hypersensitivity of human astrocytoma cell lines cultured in the presence of sodium butyrate (compared to sodium propionate and capronate) and the increased VT sensitivity of multiple drug-resistant mutants as compared to parental human ovarian carcinoma cells. In both cases, a difference in the intracellular retrograde transport of the receptor-bound internalized toxin to the ER/nuclear envelope, as opposed to the Golgi, correlated with a 〉1,000-fold increase in cell sensitivity to VT. This change in intracellular routing may be due to sorting of Gb3 fatty acid isoforms, since nuclear targeting was found in turn to correlate with the preferential synthesis of Gb3 containing shorter chain (primarily C16) fatty acid species. We propose that the isoform-dependent traffic of Gb3 from the cell surface to the ER/nuclear membrane provides a new signal transduction pathway for Gb3 binding proteins. J Cell Physiol 177:646-660, 1998. © 1998 Wiley-Liss, Inc.
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  • 80
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    Journal of Cellular Biochemistry 71 (1998), S. 313-327 
    ISSN: 0730-2312
    Keywords: articular cartilage repair ; tissue engineering ; collagen type II ; collagen type IX ; collagen network ; pyridinium crosslinks ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: The function of articular cartilage as a weight-bearing tissue depends on the specific arrangement of collagen types II and IX into a three-dimensional organized collagen network that can balance the swelling pressure of the proteoglycan/ water gel. To determine whether cartilage engineered in vitro contains a functional collagen network, chondrocyte-polymer constructs were cultured for up to 6 weeks and analyzed with respect to the composition and ultrastructure of collagen by using biochemical and immunochemical methods and scanning electron microscopy. Total collagen content and the concentration of pyridinium crosslinks were significantly (57% and 70%, respectively) lower in tissue-engineered cartilage that in bovine calf articular cartilage. However, the fractions of collagen types II, IX, and X and the collagen network organization, density, and fibril diameter in engineered cartilage were not significantly different from those in natural articular cartilage. The implications of these findings for the field of tissue engineering are that differentiated chondrocytes are capable of forming a complex structure of collagen matrix in vitro, producing a tissue similar to natural articular cartilage on an ultrastructural scale. J. Cell. Biochem. 71:313-327, 1998. © 1998 Wiley-Liss, Inc.
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  • 81
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    Journal of Cellular Biochemistry 71 (1998), S. 328-339 
    ISSN: 0730-2312
    Keywords: insulin ; heart ; development ; PI 3-kinase ; protein kinase B ; S6 kinase ; casein kinase 2 ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: The control of glucose uptake and glycogen metabolism by insulin in target organs is in part mediated through the regulation of protein-serine/ threonine kinases. In this study, the expression and phosphotransferase activity levels of some of these kinases in rat heart ventricle were measured to investigate whether they might mediate the shift in the energy dependency of the developing heart from glycogen to fatty acids. Following tail-vein injection of overnight fasted adult rats with 2 U of insulin per kg body weight, protein kinase B (PKB), the 70-kDa ribosomal S6 kinase (S6K), and casein kinase 2 (CK2) were activated (30-600%), whereas the MAP/ extracellular regulated kinases (ERK)1 and ERK2 were not stimulated under these conditions. When the expression levels of the insulin-activated kinases were probed with specific antibodies in ventricular extracts from 1-, 10-, 20-, 50-, and 365-day-old rats, phosphatidylinositol 3-kinase (PI3K), PKB, S6K, and CK2 were downregulated (40-60%) with age. By contrast, ventricular glycogen synthase kinase-3β (GSK3β) protein levels were maintained during postnatal development. Similar findings were obtained when the expression of these kinases was investigated in freshly isolated ventricular myocytes, where they were detected predominantly in the cytosolic fraction of the myocytes. Compared to other adult rat tissues such as brain and liver, the levels of PI3K, PKB, S6K, and GSK3β were relatively low in the heart. Even though CK2 protein and activity levels were reduced by ∼60% in 365 day as compared to 1-day-old rats, expression of CK2 in the adult heart was as high as detected in any of the other rat tissues. The high basal activities of CK2 in early neonatal heart may be associated with the proliferating state of myocytes. J. Cell. Biochem. 71:328-339, 1998. © 1998 Wiley-Liss, Inc.
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  • 82
    ISSN: 0730-2312
    Keywords: vitamin D analogues ; vitamin D receptor ; ligand binding ; limited protease digestion ; ligand-dependent gel shift assay ; gene regulation ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: The nuclear hormone 1α,25-dihydroxyvitamin D3 (VD) has important cell-regulatory functions but also a strong calcemic effect. Therefore, various VD analogues have been synthesized and screened for their biological profile. In order to gain more insight into the molecular basis of the high antiproliferative but low calcemic action of the VD analogue EB1089, we characterized this compound in comparison to five structurally related VD analogues. The activities of the six VD analogues in in vitro assays (limited protease digestion assays for determining interaction with monomeric vitamin D receptor (VDR), ligand-dependent gel shift assays for showing the increase of DNA binding of VDR-retinoid X receptor (RXR) heterodimers, and reporter gene assays on different types of VD response elements for demonstrating the efficacy in nuclear VD signalling) were found to represent their biological potency (antiproliferative effect on different malignant cell lines). In this series, EB1089 proved to be the most potent VD analogue; that is, every structural modification (20-epi configuration, cis-configuration at position C24, or changes at the ethyl groups at position C25) appeared to reduce the determined activities mediated through the VDR of these analogues. Moreover, the modifications of EB1089 resulted in a loss of VD response element selectivity, suggesting that this parameter is very critical for the biological profile of this VD analogue. J. Cell. Biochem. 71:340-350, 1998. © 1998 Wiley-Liss, Inc.
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    Journal of Cellular Biochemistry 71 (1998), S. 363-374 
    ISSN: 0730-2312
    Keywords: nuclear matrix proteins ; preparation method ; two-dimensional polyacrylamide gel electrophoresis ; heterogeneous nuclear ribonucleoproteins ; vanadyl ribonucleoside complexes ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Comparative analysis of nuclear matrix proteins by two-dimensional electrophoresis may be greatly impaired by copurifying cytoskeletal proteins. The present data show that the bulk of adhering cytofilaments may mechanically be removed by shearing of nuclei pretreated with vanadyl ribonucleoside complexes. Potential mechanisms of action not based on ribonuclease inhibition are discussed. To individually preserve the integrity of nuclear structures, we developed protocols for the preparation of nuclear matrices from three categories of cells, namely leukocytes, cultured cells, and tissue cells. As exemplified with material from human lymphocytes, cultured amniotic cells, and liver tissue cells, the resulting patterns of nuclear matrix proteins appeared quite similar. Approximately 300 spots were shared among the cell types. Forty-nine of these were identified, 21 comprising heterogeneous nuclear ribonucleoproteins. Heterogeneous nuclear ribonucleoproteins L and nuclear lamin B2 isoforms were identified by amino acid sequencing and mass spectrometry. However, individually expressed proteins, such as the proliferating cell nuclear antigen, also pertained following application of the protocols. Thus, enhanced resolution and comparability of proteins improve systematic analyses of nuclear matrix proteins from various cellular sources. J. Cell. Biochem. 71:363-374, 1998. © 1998 Wiley-Liss, Inc.
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  • 84
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    Journal of Cellular Biochemistry 71 (1998), S. 375-381 
    ISSN: 0730-2312
    Keywords: insulin-like growth factor-I ; insulin-like growth factor binding protein-5 ; smooth muscle cells ; atherosclerosis ; substratum ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Insulin-like growth factor binding protein-5 (IGFBP-5) is synthesized and secreted by smooth muscle cells (SMC). IGFBP-5 synthesis is stimulated five- to sixfold by IGF-I, and IGFBP-5 has been shown to augment IGF-I-stimulated DNA synthesis in this cell type. The ability of IGFBP-5 to augment the SMC response to IGF-I is dependent upon its binding to extracellular matrix. A highly charged region of IGFBP-5 that contains amino acids in positions 201-218 has been shown to mediate binding of IGFBP-5 to human fibroblast extracellular matrix (ECM), and a synthetic peptide containing this sequence inhibits IGFBP-5 binding to fibroblast ECM. In this study we show that exposure of SMC cultures that are constituitively synthesizing IGFBP-5 to a synthetic peptide (termed peptide A) containing this sequence has no effect on its synthesis but reduces its abundance within the ECM. The addition of increasing concentrations of the peptide to SMC cultures resulted in a concentration-dependent reduction in ECM-associated IGFBP-5. In contrast, a control peptide (peptide B), which contained the region of amino acids in positions 131-141 and had a similar charge-to-mass ratio, caused a minimal decrease in ECM binding. This effect was functionally significant since the addition of 10 μg/ ml of peptide A inhibited the cellular replication response to 10 ng/ ml IGF-I by 51%, and peptide B had no effect. The effects of peptide A were not due to nonspecific cytotoxicity since it had no inhibitory effect on the response of these cells to human serum and was associated with only minimal inhibition of the cellular response to platelet-derived growth factor. The findings suggest that inhibiting IGFBP-5 binding to porcine SMC ECM results in reduced cellular responses to IGF-I. J. Cell. Biochem. 71:375-381, 1998. © 1998 Wiley-Liss, Inc.
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  • 85
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    Journal of Cellular Biochemistry 71 (1998), S. 382-391 
    ISSN: 0730-2312
    Keywords: dexamethasone ; bone marrow cell cultures ; IGF-I ; vertebrae ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Osteoblast-like cell cultures have been established from the marrow of adult rat vertebrae. We have simultaneously examined the response to dexamethasone (dex) treatment in cultures of young adult female vertebral and femoral marrow cells. Alkaline phosphatase (AP) activity was analyzed as well as the expression of mRNAs for osteocalcin (OC) and insulin-like growth factor I (IGF-I). The vertebral and femoral marrow cells were maintained for 7 days in primary culture with or without 10-8 M dex and then 6 days in secondary culture without dex or with 10-8 M or 10-7 M dex. All cells were examined on day 6 of secondary culture. Vertebral and femoral cultures each expressed the highest AP enzyme levels when grown with dex in primary culture (10-8 M) and secondary culture (10-7 M). Under all experimental conditions, vertebral cultures had lower AP enzyme activity than femoral cultures. When dex was omitted from secondary culture, OC gene expression was not detected in either vertebral or femoral passaged cells even if dex was present in primary culture. For dex conditions where OC was expressed, vertebral cultures had higher OC mRNA steady-state levels than femoral cultures. IGF-I gene expression was detected by Northern analysis in both vertebral and femoral secondary cultures. However, vertebral marrow cultures had much higher IGF-I mRNA levels compared to femoral cultures whether or not dex was present in primary culture. These findings demonstrate that dex supports the differentiation of both vertebral and femoral adult marrow osteogenic cells into osteoblasts. Our results support the hypothesis that osteoblastic marrow cultures differ depending upon which location in the skeleton they are from and that there are skeletal site-dependent differences in the insulin-like growth factor system components. J. Cell. Biochem. 71:382-391, 1998. © 1998 Wiley-Liss, Inc.
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  • 86
    ISSN: 0730-2312
    Keywords: apoptosis ; necrosis ; phospholipases ; tumor necrosis factor ; Fas ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Phospholipases generate important secondary messengers in several cellular processes, including cell death. Tumor necrosis factor (TNF) can induce two distinct modes of cell death, viz. necrosis and apoptosis. Here we demonstrate that phospholipase D (PLD) and cytosolic phospholipase A2 (cPLA2) are differentially activated during TNF-induced necrosis or apoptosis. Moreover, a comparative study using TNF and anti-Fas antibodies as cell death stimuli showed that PLD and cPLA2 are specifically activated by TNF. These results indicate that both the mode of cell death and the type of death stimulus determine the potential role of phospholipases as generators of secondary messengers. J. Cell. Biochem. 71:392-399, 1998. © 1998 Wiley-Liss, Inc.
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  • 87
    ISSN: 0730-2312
    Keywords: IGFBP ; cAMP ; PKA ; prostaglandin ; bone ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Insulin-like growth factor (IGF)-I and IGF-II are expressed at biologically effective levels by bone cells. Their stability and activity are modulated by coexpression of IGF binding proteins (IGFBPs). Secreted IGFBPs may partition to soluble, cell-associated, and matrix-bound compartments. Extracellular localization may sequester, store, or present IGFs to appropriate receptors. Of the six IGFBPs known, rat osteoblasts synthesize all but IGFBP-1. Of these, IGFBP-3, -4, and -5 mRNAs are induced by an increase in cAMP. Little is known about extracellular IGFBP localization in bone and nothing about IGFBP expression by nonosteoblastic periosteal bone cells. We compared basal IGFBP expression in periosteal and osteoblast bone cell cultures and assessed the effects of changes in cAMP-dependent protein kinase A or protein kinase C. Basal IGFBP gene expression differed principally in that more IGFBP-2 and -5 occurred in osteoblast cultures, and more IGFBP-3 and -6 occurred in periosteal cultures. An increase in cAMP enhanced IGFBP-3, -4, and -5 mRNA and accordingly increased soluble IGFBP-3, -4, and -5 and matrix-bound IGFBP-3 and -5 in both bone cell populations. In contrast, protein kinase C activators suppressed IGFBP-5 mRNA, and its basal protein levels remained very low. We also detected low Mr bands reactive with antisera to IGFBP-2, -3, and -5, suggesting proteolytic processing or degradation. Our studies reveal that various bone cell populations secrete and bind IGFBPs in selective ways. Importantly, inhibitory IGFBP-4 does not significantly accumulate in cell-associated compartments, even though its secretion is enhanced by cAMP. Because IGFBPs bind IGFs less tightly in cell-bound compartments, they may prolong anabolic effects by agents that increase bone cell cAMP. J. Cell. Biochem. 71:351-362, 1998. © 1998 Wiley-Liss, Inc.
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  • 88
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    Journal of Cellular Biochemistry 72 (1998), S. 8-17 
    ISSN: 0730-2312
    Keywords: eukaryote ; DNA replication ; replication origin ; pre-replication complex ; initiation proteins ; origin recognition complex ; DNA unwinding ; nuclear structure ; chromatin structure ; DNA methylation ; animal development ; metazoa ; mammal ; frog ; fly ; yeast ; Xenopus ; Drosophila ; Sciara ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Our understanding of the process by which eukaryotes regulate initiation of DNA replication has made remarkable advances in the past few years, thanks in large part to the explosion of genetic and biochemical information on the budding yeast, Saccharomyces cerevisiae. At least three major concepts have emerged: 1) The sequence of molecular events that determines when replication begins and how frequently each replication site is used are conserved among most, if not all, eukaryotes; 2) specific replication origins are used in most, if not all, eukaryotes that consist of a flexible modular anatomy; and 3) epigenetic factors such as chromatin structure and nuclear organization determine which of many potential replication origins are used at different stages in animal development. Thus, the current state of our knowledge suggests a simple unifying concept - all eukaryotes utilize the same basic proteins and DNA sequences to initiate replication, but the metazoa can change both the number and locations of replication origins in response to the demands of animal development. J. Cell. Biochem. Suppls. 30/31:8-17, 1998.
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  • 89
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    Journal of Cellular Biochemistry 72 (1998), S. 168-176 
    ISSN: 0730-2312
    Keywords: cadherin ; catenin ; differentiation ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Cadherins form a family of cell-cell adhesion proteins that are critical to normal embryonic development. Expression of the various family members is regulated in a complex pattern during embryogenesis. Both reduced and inappropriate expression of cadherins have been associated with abnormal tissue formation in embryos and tumorigenesis in mature organisms. Evidence is accumulating that signals unique to individual members of the cadherin family, as well as signals common to multiple cadherins, contribute to the differentiated phenotype of various cell types. While a complete understanding of the regulation of cadherin expression of the molecular nature of intracellular signaling downstream of cadherin adhesion is essential to an understanding of embryogenesis and tumorigenesis, our knowledge in both areas is inadequate. Clearly, elucidating the factors and conditions that regulate cadherin expression and defining the signaling pathways activated by cadherins are frontiers for future research. J. Cell. Biochem. Suppls. 30/31:168-176, 1998. © 1998 Wiley-Liss, Inc.
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  • 90
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    Journal of Cellular Biochemistry 72 (1998), S. 129-136 
    ISSN: 0730-2312
    Keywords: protein kinase CK2 ; holoenzyme ; α- and β-subunits ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Protein kinase CK2 is a ubiquitous eukaryotic ser/thr protein kinase. The active holoenzyme is a heterotetrameric protein composed of catalytic (α and α′) and regulatory (β) subunits that phosphorylates many different protein substrates and appears to be involved in the regulation of cell division. Despite important structural studies, the intimate details of the interactions of the α catalytic subunits with the β regulatory subunits are unknown. Recent evidence that indicates that both CK2 subunits can interact promiscuously with other proteins in a manner that excludes the binding of their complementary CK2 partners has opened the possibility that the phosphorylating activity of this enzyme may be regulated in a novel way. These alternative interactions could limit the in vivo availability of CK2 subunits to generate fully active holoenzyme CK2 tetramers. Likewise, variations in the ratio of α- and β-subunits could determine the activity of several phosphorylating and dephosphorylating activities. The promiscuity of the CK2 subunits can be extrapolated to a more widespread phenomenon in which “wild-card” proteins could act as general switches by interacting and regulating several catalytic activities. J. Cell. Biochem. Suppls. 30/31:129-136, 1998. © 1998 Wiley-Liss, Inc.
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  • 91
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    Journal of Cellular Biochemistry 72 (1998), S. 177-184 
    ISSN: 0730-2312
    Keywords: nucleosome ; chromosomes ; DNA ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: No abstract.
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  • 92
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    Journal of Cellular Biochemistry 72 (1998), S. 194-202 
    ISSN: 0730-2312
    Keywords: acute leukemias ; hematopoietic cells ; histone deacetylase complexes ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Accumulating evidence points to a connection between cancer and transcriptional control by histone acetylation and deacetylation. This is particularly true with regard to the acute leukemias, many of which are caused by fusion proteins that have been created by chromosomal translocations. Genetic rearrangements that disrupt the retinoic acid receptor-α and acute myeloid leukemia-1 genes create fusion proteins that block terminal differentiation of hematopoietic cells by repressing transcription. These fusion proteins interact with nuclear hormone co-repressors, which recruit histone deacetylases to promoters to repress transcription. This finding suggests that proteins within the histone deacetylase complexes may be potential targets for pharmaceutical intervention in many leukemia patients. J. Cell. Biochem. Suppls. 30/31:194-202, 1998. © 1998 Wiley-Liss, Inc.
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  • 93
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    Journal of Cellular Biochemistry 72 (1998), S. 185-193 
    ISSN: 0730-2312
    Keywords: steroid receptor action ; co-repressors ; co-activators ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: During the past few years, our understanding of nuclear receptor action has dramatically improved as a result of the identification and functional analysis of co-regulators such as factors involved in chromatin remodeling, transcription intermediary factors (co-repressors and co-activators), and direct interactions with the basal transcriptional machinery. Furthermore, the elucidation of the crystal structures of the empty ligand-binding domains of the nuclear receptor and of complexes formed by the nuclear receptor's ligand-binding domain bound to agonists and antagonists has contributed significantly to our understanding of the early events of nuclear receptor action. However, the picture of hormone- and hormone receptor-mediated mechanisms of gene regulation remain incomplete and extremely complicated when one also considers the “nontraditional” interactions of hormone-activated nuclear receptors, for example, interactions between the activated steroid receptors and components of the chromatin/nuclear matrix; and finally the nongenomic effects that steroid hormones can exhibit with other signaling pathways. In this prospectus on steroid receptors, we discuss the implications of various steroid hormone and nuclear receptor interactions and potential future directions of investigation. J. Cell. Biochem. Suppls. 30/31:185-193, 1998. © 1999 Wiley-Liss, Inc.
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  • 94
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    Journal of Cellular Biochemistry 72 (1998), S. 214-219 
    ISSN: 0730-2312
    Keywords: nucleus ; nuclear envelope ; nuclear export ; nuclear import ; regulation ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: The control of transcription and translation is of fundamental importance in cell biology. In this regard, the nuclear envelope is in a unique position to contribute to the regulation of these events, by directing macromolecular exchanges between the nucleus and cytoplasm. Such exchanges occur through the nuclear pore complexes, mainly by signal-mediated processes. Different signals are required for import and export. Specific cytoplasmic or nuclear receptors initially bind the signal-containing substrate, and the complex subsequently interacts with the pores. Additional factors then assist in translocation across the envelope. Current research is focused mainly on further characterization of transport receptors, translocation factors, as well as components of the nuclear pore complex, i.e., the nucleoporins. The ultimate goal is to understand the molecular interactions that occur among the different components of the transport apparatus, the energy sources for transport, and how variations in transport capacity are generated. J. Cell. Biochem. Suppls. 30/31:214-219, 1998. © 1998 Wiley-Liss, Inc.
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  • 95
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    Journal of Cellular Biochemistry 72 (1998), S. 220-231 
    ISSN: 0730-2312
    Keywords: nuclear architecture ; gene expression ; tumor cells ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Functional interrelationships between components of nuclear architecture and control of gene expression are becoming increasingly evident. There is growing appreciation that multiple levels of nuclear organization integrate the regulatory cues that support activation and suppression of genes as well as the processing of gene transcripts. The linear organization of genes and promoter elements provide the potential for responsiveness to physiological regulatory signals. Parameters of chromatin structure and nucleosome organization support synergism between activities at independent regulatory sequences and render promoter elements accessible or refractory to transcription factors. Association of genes, transcription factors, and the machinery for transcript processing with the nuclear matrix facilitates fidelity of gene expression within the three-dimensional context of nuclear architecture. Mechanisms must be defined that couple nuclear morphology with enzymatic parameters of gene expression. The recent characterization of factors that mediate chromatin remodeling and intranuclear targeting signals that direct transcription factors to subnuclear domains where gene expression occurs, reflect linkage of genetic and structural components of transcriptional control. Nuclear reorganization and aberrant intranuclear trafficking of transcription factors for developmental and tissue-specific control that occurs in tumor cells and in neurological disorders provides a basis for high resolution diagnostics and targeted therapy. J. Cell. Biochem. Suppls. 30/31:220-231, 1998. © 1998 Wiley-Liss, Inc.
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  • 96
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    Journal of Cellular Biochemistry 72 (1998), S. 232-237 
    ISSN: 0730-2312
    Keywords: cytoskeleton, mechanotransduction, integrins, cell architecture, tensegrity ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: The field of molecular cell biology has experienced enormous advances over the last century by reducing the complexity of living cells into simpler molecular components and binding interactions that are amenable to rigorous biochemical analysis. However, as our tools become more powerful, there is a tendency to define mechanisms by what we can measure. The field is currently dominated by efforts to identify the key molecules and sequences that mediate the function of critical receptors, signal transducers, and molecular switches. Unfortunately, these conventional experimental approaches ignore the importance of supramolecular control mechanisms that play a critical role in cellular regulation. Thus, the significance of individual molecular constituents cannot be fully understood when studied in isolation because their function may vary depending on their context within the structural complexity of the living cell. These higher-order regulatory mechanisms are based on the cell's use of a form of solid-state biochemistry in which molecular components that mediate biochemical processing and signal transduction are immobilized on insoluble cytoskeletal scaffolds in the cytoplasm and nucleus. Key to the understanding of this form of cellular regulation is the realization that chemistry is structure and hence, recognition of the importance of architecture and mechanics for signal integration and biochemical control. Recent work that has unified chemical and mechanical signaling pathways provides a glimpse of how this form of higher-order cellular control may function and where paths may lie in the future. J. Cell. Biochem. Suppls. 30/31:232-237, 1998. © 1998 Wiley-Liss, Inc.
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  • 97
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    Journal of Cellular Biochemistry 72 (1998), S. 250-263 
    ISSN: 0730-2312
    Keywords: signal transduction ; cell adhesion complexes ; membrane skeleton ; nucleo-cytoplasmic translocation ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Understanding how the information is conveyed from outside to inside the cell is a critical challenge for all biologists involved in signal transduction. The flow of information initiated by cell-cell and cell-extracellular matrix contacts is mediated by the formation of adhesion complexes involving multiple proteins. Inside adhesion complexes, connective membrane skeleton (CMS) proteins are signal transducers that bind to adhesion molecules, organize the cytoskeleton, and initiate biochemical cascades. Adhesion complex-mediated signal transduction ultimately directs the formation of supramolecular structures in the cell nucleus, as illustrated by the establishment of multi complexes of DNA-bound transcription factors, and the redistribution of nuclear structural proteins to form nuclear subdomains. Recently, several CMS proteins have been observed to travel to the cell nucleus, suggesting a distinctive role for these proteins in signal transduction. This review focuses on the nuclear translocation of structural signal transducers of the membrane skeleton and also extends our analysis to possible translocation of resident nuclear proteins to the membrane skeleton. This leads us to envision the communication between spatially distant cellular compartments (i.e., membrane skeleton and cell nucleus) as a bidirectional flow of information (a dynamic reciprocity) based on subtle multilevel structural and biochemical equilibria. At one level, it is mediated by the interaction between structural signal transducers and their binding partners, at another level it may be mediated by the balance and integration of signal transducers in different cellular compartments. J. Cell. Biochem. Suppls. 30/31:250-263, 1998. © 1998 Wiley-Liss, Inc.
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  • 98
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    Journal of Cellular Biochemistry 72 (1998), S. 284-285 
    ISSN: 0730-2312
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: No abstract.
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  • 99
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    Journal of Cellular Biochemistry 72 (1998), S. 297-303 
    ISSN: 0730-2312
    Keywords: tissue engineering ; biomaterials ; cell culture ; polymers ; transplants ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: This article reviews the important developments in the field of tissue engineering over the last 10 years. Research in the area of biomaterials is examined from the perspective of providing the foundation for the development of tissue engineering. Early efforts combining cells with biocompatible materials are described and applications of this technology presented, with particular focus on uses in orthopaedics and maxillofacial surgery. The basic principles of tissue engineering and state-of-the-art technology in cell biology and materials science as used currently in the field are presented. Finally, futures challenges are outlined from the perspective of integrating technologies from medicine, biology, and engineering, in hopes of translating tissue engineering to clinical applications. J. Cell. Biochem. Suppls. 30/31:297-303, 1998. © 1998 Wiley-Liss, Inc.
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  • 100
    ISSN: 0730-2312
    Keywords: EST ; cDNA microarray ; RDA ; osteoblast differentiation ; pax-6 ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Elucidation of the changes in gene expression associated with biological processes is a central problem in biology. Advances in molecular and computational biology have led to the development of powerful, high-thoughput methods for the analysis of differential gene expression. These tools have opened up new opportunities in disciplines ranging from cell and developmental biology to drug development and pharmacogenomics. In this review, the attributes of five commonly used differential gene expression methods are discussed: expressed sequence tag (EST) sequencing, cDNA microarray hybridization, subtractive cloning, differential display, and serial analysis of gene expression (SAGE). The application of EST sequencing and microarray hybridization is illustrated by the discovery of novel genes associated with osteoblast differentiation. The application of subtractive cloning is presented as a tool to identify genes regulated in vivo by the transcription factor pax-6. These and other examples illustrate the power of genomics for discovering novel genes that are important in biology and which also represent new targets for drug development. The central theme of the review is that each of the approaches to identifying differentially expressed genes is useful, and that the experimental context and subsequent evaluation of differentially expressed genes are the critical features that determine success. J. Cell. Biochem. Suppls. 30/31:286-296, 1998. © 1998 Wiley-Liss, Inc.
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