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  • 101
    Keywords: Microbiology. ; Renewable energy sources. ; Microbiology. ; Renewable Energy.
    Description / Table of Contents: Chapter 1. Advancements in Biofuel Production -- Chapter 2. Bionenergy: Sustainable Renewable Energy -- Chapter 3. Biofuel from Microalgae -- Chapter 4. Waste to bioenergy: Recent Technologies -- Chapter 5. Bioenergy from Agricultural Wastes -- Chapter 6. Bio-Processing: Biomass to Commercial Alcohol -- Chapter 7. Hydrogen Production by Utilizing Bio-Processing Techniques -- Chapter 8. Bacterial Hydrogen Production: Prospects and Challenges -- Chapter 9. Bioethanol Production from Biodiesel Derived Glycerol – A Case Study -- Chapter 10. Advancement on biomass classification, analytical methods for characterization and its economic importance.
    Abstract: This volume is fourth part of the five-part set on bioenergy research. This volume covers biomass to bioenergy production concept. The book is focused on the possible and versatile biomass options available for the generation of bioenergy. Additionally, the book also explores different types of biomass for bioenergy generation at a commercial level. Further, the book elaborates on different kind of cellulose and sugar rich waste which can also be utilized for bioenergy production. It covers other relevant issues such as recent technological advancement in biomass to bioenergy conversion, waste management in the context of biomass to biofuels production technologies, green methods of energy production, alternates of fossil fuels in the near future. It also explores biomass waste valorization, utilizing microbial processes in bioenergy production. This is a useful reading material for students, researchers, industry and policy experts. Other four volumes of this set explore basic concepts, latest progress, commercial opportunities and integrated solution for bioenergy concerns. .
    Type of Medium: Online Resource
    Pages: XI, 272 p. 35 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811618628
    Series Statement: Clean Energy Production Technologies,
    DDC: 579
    Language: English
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  • 102
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Internal medicine. ; Hematology. ; Biomedical Research. ; Cell Biology. ; Internal Medicine. ; Hematology.
    Description / Table of Contents: Live Donors of Tissue -- Deceased Tissue Donors -- Banking and Use of Umbilical Cord Blood -- Ocular tissue banking -- Banking of Heart Valves -- Cryopreservation and Banking of Haematopoietic Progenitor Cells -- Storage, Processing and Preservation -- Cryopreservation in tissue banking -- Sterilisation by Irradiation -- Screening the tissue donor for infectious agents -- Contamination in the Tissue Way -- Establishing a Quality System in a Tissue Establishment -- IT System requirements for Tissue and Cell Banking -- Ethical and Regulatory Aspects of Cell and Tissue Banking -- Human embryonic stem cell banking for clinical applications – 20 years from their isolation.
    Abstract: It has been 10 years since the first edition of ‘Essentials of Tissue Banking’ has been published. There is still relatively little published on the technical and scientific principles on routine tissue and cell banking based on scientific principles. The 1st edition was very successful and, after a 10 year gap, there is a need of an update and an expansion of the book’s remit. The format of the book follows that of the previous edition- split into 5 sections. Management of donors and the banking of common tissues and cells; Principles of storage and processing of tissues and cells; Ensuring the safety of the products by testing the donor, the tissues and the environment, supported by a quality system and an IT infrastructure- all working within the constraints of current regulatory and ethical environments. This edition however provides a significant update. Many the chapters have been completely rewritten by different experts. Like the 1st edition, they were given a free hand in the way they wrote their chapter, with a guideline that they had to be concise, clear and up to date. The authors were also asked to provide the scientific and technical basis that provides the rationale of the processes they describe. Also, the scope of the book has been somewhat extended. In view of the fact that many cellular therapies are now routinely practiced, 2 new chapters have been added: one on the banking of haematopoietic stem cells and one on human embryonic stem cells. They have been deliberately chosen to illustrate the extreme spectrum of cellular therapies from one of the simplest to one of the most complex. The intention of the book has remained the same: to cover and update banking of current practices in essential tissue and cell banking. It is therefore hoped that by keeping the book as concise and up to date as possible, it will find a place on the shelves of many tissue establishments.
    Type of Medium: Online Resource
    Pages: VIII, 288 p. 48 illus., 28 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030716219
    DDC: 610.72
    Language: English
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  • 103
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medical microbiology. ; Pharmacology. ; Pediatrics. ; Medical Microbiology. ; Pharmacology. ; Pediatrics.
    Description / Table of Contents: Part 1 General Vaccinology -- 1 Expected and Unexpected Effects of Vaccination -- 2 How Vaccinating People Can Also Protect Others -- 3 Childhood and Adolescent Immunization Programs in Europe -- 4 Vaccine Hesitancy, Acceptance, and Demand -- 5 Adjuvants in Pediatric Vaccines -- 6 Maternal Immunization -- 7 Neonatal Immunization -- Part 2 Viral Vaccines and Vaccinations -- 8 Poliovirus Vaccines -- 9 Measles–Mumps–Rubella Vaccine -- 10 Varicella Vaccines -- 11 Rotavirus Vaccine -- 12 Hepatitis A Vaccines -- 13 Hepatitis B Vaccines -- 14 Influenza Vaccines -- 15 Human Papillomavirus Vaccines -- 16 Tick-Borne Encephalitis Vaccines -- Part 3 Bacterial Vaccines and Vaccination -- 17 Tuberculosis Vaccines -- 18 Pertussis Vaccines -- 19 Haemophilus influenzae type b (Hib) Vaccines -- 20 Pediatric Combination Vaccines -- 21 Pneumococcal Vaccines -- 22 Meningococcal Vaccines -- 23 Pediatric Vaccines for Travel Outside Europe -- Part 4 New Vaccines in Pipeline Development -- 24 GBS and CMV Vaccines in Pipeline Development -- 25 Norovirus Vaccines in Pipeline Development -- 26 RSV Vaccines and Monoclonal Antibodies in Development -- 27 COVID-19 in Children and COVID-19 Vaccines -- 28 Registration of Vaccines, Safety Follow-Up, and Pediatric Investigation Plan.
    Abstract: This second fully updated and extended edition of the textbook serves as a highly readable guide on latest developments in vaccine development and vaccination programs in infants, children and adolescents from a European perspective. The first part of the book introduces to general vaccinology, immunization programs and formulation, effects and unwanted effects of vaccines. The second and third part provide an overview on current viral and bacterial vaccines. The fourth and last part of this book discusses new vaccines in the pipeline and gives insights into safety and regulatory matters. This second edition is extended by a whole new chapter on COVID-19 vaccines. This book serves as a reference textbook in the field and helps to standardize the information on vaccines and immunization programs in the WHO European Region.
    Type of Medium: Online Resource
    Pages: XIII, 319 p. 66 illus., 63 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030771737
    DDC: 616.9041
    Language: English
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  • 104
    Keywords: Ecology . ; Conservation biology. ; Biotic communities. ; Population biology. ; Plant ecology. ; Animal culture. ; Ecology. ; Conservation Biology. ; Community and Population Ecology. ; Plant Ecology. ; Animal Science.
    Description / Table of Contents: Section 1 -- Chapter 1. Introduction -- Section 2. Plant Diversity -- Chapter 2. Status, issues and challenges of biodiversity:Lower plants (Non-vascular) -- Chapter 3. Status, issues and Challenges of Biodiversity:Higher Plants -- Chapter 4. Status, issues and challenges of biodiversity: Trees and Shrubs -- Chapter 5. Underutilized Plant Strength of India -- Section 3. Faunal Diversity -- Chapter 6. Status, Issues and Challenges of Biodiversity: Invertebrate -- Chapter 7. Diversity, Distribution and Endemicity of Herpetofauna in Different Biogeographic Zones and Biodiversity Hotpots of India -- Chapter 8. Status, Issues, and Challenges of Biodiversity: Wild Animals -- Chapter 9. Indian Avian Diversity:Status, Challenges and Solutions -- Chapter 10. Status, Issues and Challenges of Indian Livestock Biodiversity -- Section 4. Ecosystem Diversity -- Chapter 11. Agricultural Crop Diversity: Status, Challenges and Solutions -- Chapter 12. Biodiversity of Agriculturally Important Insects: Status, Issues and Challenges -- Chapter 13. Biodiversity Issues and Challenges:Non-Agriculture Insects -- Chapter 14. Status, issues and challenges of biodiversity: Forest Insects -- Chapter 15. Status, Issues and Challenges of Biodiversity: Marine Biota -- Chapter 16. Diatoms the living jewels their biodiversity, phycosphere and associated phenotypic plasticity: a lesson to learn from current pandemic of corona virus -- Chapter 17. Plant Diversity at Ecosystems level in India: Dynamics and Status -- Chapter 18. Faunal Diversity at Ecosystems level in India: Dynamics and Status -- Section 5. Challenges and reasons of Biodiversity loss -- Chapter 19. Challenges on Account of Invasive Alien Terrestrial Plants -- Chapter 20. Alien Invasive Aquatic Fauna:Challenges and Mitigation -- Chapter 21. Reasons of Biodiversity Loss in India -- Section 6. Efforts Conservation -- Chapter 22. Conservation of National Biodiversity: Efforts of the Indian Government -- Chapter 23. Legal Framework for Conservation of Biodiversity in India -- Chapter 24. Index.
    Abstract: This contributed book is based on the current status of biodiversity in India, issues and challenges faced by the authorities involved in conservation efforts, and the imperative role of various direct and indirect stakeholders in biodiversity conservation. The book discusses the current status of different forms of biodiversity in India, challenges faced by stakeholders, issues and reasons for biodiversity losses, and efforts by government through various laws, policies, and programs in a concise and comprehensive manner throughout its many chapters. In this way, readers can access diverse information on Indian biodiversity through this book. It is compiled by leading experts in the field of conservation. In 18 chapters, it covers biodiversity of both fauna and flora, on land and in aquatic ecosystems, legal and policy aspects, as well as innovative conservation tool and techniques. It is useful for undergraduates and graduate students and also educates policy planners, bureaucrats, foresters, and researchers in India and abroad.
    Type of Medium: Online Resource
    Pages: X, 665 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811697777
    DDC: 577
    Language: English
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  • 105
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biophysics. ; Cell interaction. ; Biomedical engineering. ; Cardiovascular system. ; Physiology. ; Cardiography. ; Molecular biology. ; Clinical biochemistry. ; Mechanobiological Cell Signaling. ; Biomedical Engineering and Bioengineering. ; Cardiovascular Physiology. ; Cardiography. ; Molecular Biology. ; Medical Biochemistry.
    Description / Table of Contents: Part 1: Cardiac Signaling -- Chapter 1: Calcium-Dependent Signaling in Cardiac Myocytes -- Chapter 2: Organization of Ca2+ Signaling Microdomains in Cardiac Myocytes -- Chapter 3: Stress Kinase Signaling in Cardiac Myocytes -- Chapter 4: Cardiotoxicity and cardiac cell signaling -- Chapter 5: Protein Phosphatase Signaling in Cardiac Myocytes -- Chapter 6: Metabolic Regulation of Mitochondrial Dynamics and Cardiac Function -- Chapter 7: NADPH Oxidase System Mediates Cholesterol Secoaldehyde-Induced Oxidative Stress and Cytotoxicity in H9c2 Cardiomyocytes -- Chapter 8: Lipid Mediators in Cardiovascular Physiology and Disease -- Chapter 9: Cardiac Inflammasome and Arrhythmia -- Chapter 10: Myocardial Fibrosis: Cell Signaling and In Vitro Modeling -- Chapter 11: Neural regulation of cardiac rhythm -- Part 2: Vascular Signaling -- Chapter 12: Mechanisms of lipoproteins and reverse cholesterol transport in atherosclerotic cardiovascular disease -- Chapter 13: Atherosclerotic plaque regression: Future perspective -- Chapter 14: Role of Bioactive Lipid, Phosphatidic Acid in Hypercholesterolemia Drug-induced Myotoxicity – Statin-induced Phospholipase D (PLD) Lipid Signaling in Skeletal Muscle Cells -- Chapter 15: Cell-Cell Communication in the Vascular Endothelium -- Chapter 16: Lysophosphatidic acid regulates endothelial barrier integrity -- Chapter 17: Regulation of Vascular Endothelial Barrier Integrity and Function by Lipid-Derived Mediators -- Chapter 18: Hyperglycemic Oxoaldehyde (Glyoxal)-induced Vascular Endothelial Cell Damage through Oxidative Stress is protected by Thiol Iron Chelator, Dimercaptosuccinic Acid – Role of Iron in Diabetic Vascular Endothelial Dysfunction.
    Abstract: This contributed volume focuses on cardiovascular diseases (CVDs), and explores the ways in which signaling mechanisms at the biochemical, molecular, and cellular levels in the blood vessels (vascular) and heart contribute to the underlying causes of development and progression of the CVDs. This volume covers unique topics such as oxidant signaling in vascular and heart diseases and health, cytoskeletal signaling in vascular health and disease, phospholipase signaling in CVDs, lipid signaling in vascular and myocardial health and diseases, and drug discovery in cellular signaling for cardiovascular diseases. This book assembles the most important discoveries made by leaders on the cellular signaling mechanisms operating behind the development and progression of life-threatening CVDs. It is an extremely useful resource for the investigators in the field of CVDs, and opens the discussion for further discovery of efficient management and effective treatment of the CVDs.
    Type of Medium: Online Resource
    Pages: XVIII, 527 p. 83 illus., 59 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031083099
    DDC: 571.4
    Language: English
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  • 106
    Keywords: Aging. ; Cytology. ; Clinical biochemistry. ; Proteins . ; Ageing. ; Cell Biology. ; Medical Biochemistry. ; Protein Biochemistry.
    Description / Table of Contents: Chapter 1:Introduction: Historical Development and Progression of Clinical Research on Ageing -- Chapter 2:Bone Cells Metabolic Changes Induced by Ageing -- Chapter 3:Chronic Inflammation as an Underlying Mechanism of Ageing and Ageing-related Diseases -- Chapter 4: Heart Disease and Ageing: The roles of Senescence, Mitochondria and Telomerase in Cardiovascular Disease -- Chapter 5: Chronic Kidney Disease and the Exposome of Ageing -- Chapter 6: Sarcopenia and Ageing -- Chapter 7: Tendon Ageing -- Chapter 8: Virus Infections in Older People -- Chapter 9: Models and Biomarkers for Ovarian Ageing -- Chapter 10: Ageing and the Autonomic Nervous System -- Chapter 11: Astrocytes in Ageing -- Chapter 12: Hearing and Ageing -- Chapter 13: Melatonin and Ageing -- Chapter 14: Protein and Energy Supplements for the Elderly -- Chapter 15: Ageing, Metabolic Dysfunction, and the Therapeutic Role of Antioxidants -- Chapter 16: Clinical Ageing.
    Abstract: This book provides an up-to-date overview of key areas of ageing research and bridges the gap between the subcellular events and the reality of ageing as seen in clinical practice. To this end, the reader learns about the historical development and progression of clinical ageing research. All chapters address the biochemistry or cell biology of various ageing events (to the extent that the data are available) and work their way to the clinical understanding we have of ageing. The focus of this volume is on how dietary restriction, virus infection and chronic inflammation affect the ageing process. Additionally, this book discusses how phosphate metabolism and metabolic dysfunction contribute to ageing events and how various organs and tissues (e.g. tendons, ears, heart muscle, and the endocrine system) age. This book follows on from Parts I, II and III of Biochemistry and Cell Biology of Ageing within the Subcellular Biochemistry book series and aims to bring the subcellular and clinical areas into closer contact by including interesting and significant biomedical ageing topics that were not included in the earlier volumes. Comprehensive and cutting-edge, this book is a valuable resource for experienced researchers and early career scientist alike, who are interested in learning more about the fascinating and challenging question of why and how our cells age.
    Type of Medium: Online Resource
    Pages: VIII, 458 p. 48 illus., 46 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031265761
    Series Statement: Subcellular Biochemistry, 103
    DDC: 571.878
    Language: English
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  • 107
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Evolution (Biology). ; Biodiversity. ; Animal culture. ; Plant genetics. ; Climatology. ; Freshwater and Marine Ecology. ; Evolutionary Biology. ; Biodiversity. ; Animal Science. ; Plant Genetics. ; Climate Sciences.
    Description / Table of Contents: Part I: Introduction -- Marine Population Genomics: Challenges and Opportunities -- Part II: Marine Microbes -- Part III: Genetic Diversity, Population Structure, and Biogeography -- Population Genomics of Marine Zooplankton -- Population Genomics of Early-Splitting Lineages of Metazoans -- Population Genomics and Biogeography of the Northern Acorn Barnacle (Semibalanus balanoides) Using Pooled Sequencing Approaches -- Part IV: Seascape Genomics -- Seascape Genomics: Contextualizing Adaptive and Neutral Genomic Variation in the Ocean Environment -- Part V: Adaptation, Acclimation, and Speciation -- Clinal Adaptation in the Marine Environment -- The Population Genomics of Parallel Adaptation: Lessons from Threespine Stickleback -- Mechanisms of Adaptive Divergence and Speciation in Littorina saxatilis: Integrating Knowledge from Ecology and Genetics with New Data Emerging from Genomic Studies -- Ecological Speciation in Corals -- Environmental Epigenomics and Its Applications in Marine Organisms -- Part VI: Protection, Conservation, and Management of Marine Organisms -- Marine Invasion Genomics: Revealing Ecological and Evolutionary Consequences of Biological Invasions -- Population Genomics Applied to Fishery Management and Conservation -- Marine Conservation and Marine Protected Areas -- Index.
    Abstract: Population genomics has provided unprecedented opportunities to unravel the mysteries of marine organisms in the oceans' depths. The world's oceans, which make up 70% of our planet, encompass diverse habitats and host numerous unexplored populations and species. Population genomics studies of marine organisms are rapidly emerging and have the potential to transform our understanding of marine populations, species, and ecosystems, providing insights into how these organisms are evolving and how they respond to different stimuli and environments. This knowledge is critical for understanding the fundamental aspects of marine life, how marine organisms will respond to environmental changes, and how we can better protect and preserve marine biodiversity and resources. This book brings together leading experts in the field to address critical aspects of fundamental and applied research in marine species and share their research and insights crucial for understanding marine ecosystem diversity and function. It also discusses the challenges, opportunities and future perspectives of marine population genomics. .
    Type of Medium: Online Resource
    Pages: XVI, 456 p. 75 illus., 44 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030379360
    Series Statement: Population Genomics,
    DDC: 577.6
    Language: English
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  • 108
    Keywords: Biotechnology. ; Food science. ; Microbiology. ; Biotechnology. ; Food Science. ; Microbiology.
    Description / Table of Contents: Part 1. Microalgae in Food Product Development -- Chapter 1. Food and high value products from microalgae: market opportunities and challenges -- Chapter 2. Algae as a mainstream food ingredient: demand and supply perspective -- Chapter 3. Microalgae pigments: a source of natural food color -- Chapter 4. Algal biotechnology: a sustainable route for omega-3 fatty acids and carotenoids production -- Part 2. Microalgae in Health Product Development -- Chapter 5. Microalgae in human health and medicine -- Chapter 6. Astaxanthin production from microalgae -- Chapter 7. Microalgae nutraceuticals: the role of lutein in human health -- Part 3. Microalgae for Cosmetic Formulations -- Chapter 8. Algae and Aging -- Chapter 9. Extracts and bioactives from microalgae (sensu stricto): opportunities and challenges for a new generation of cosmetics -- Part 4. Other High Value Application -- Chapter 10. Microalgae as Vaccine Delivery System to Aquatic Organisms -- Chapter 11. Microalgal as a sustainable source for bioplastic -- Chapter 12. Microalgae as biofertillizer in modern agriculture -- Part 5. Biomass Production -- Chapter 13. Microalgae biomass production, drying and storage -- Chapter 14. Microalgal carbohydrate and proteins: synthesis, extraction, application and challenges -- Chapter 15. Pretreatment and lipid extraction from wet microalgae: Challenges, potential and application for industrial scale application.
    Abstract: "Microalgae Biotechnology for Food, Health and High Value Products” presents the latest technological innovations in microalgae production, market status of algal biomass-based products, and future prospects for microalgal applications. It provides stimulating overviews from different perspectives of application that demonstrate how rapidly the commercial production of microalgae-based food, health and high value products is advancing. It also addresses a range of open questions and challenges in this field. The book highlights the latest advances of interest to those already working in the field, while providing a comprehensive overview for those readers just beginning to learn about the promise of microalgae as a sustainable source of both specialty and commercial products. It offers a valuable asset for commercial algae producers, algae product developers, scientific researchers and students who are dedicated to the advancement of microalgae biotechnology for applications in health, diet, nutrition, cosmetics, biomaterials etc. .
    Type of Medium: Online Resource
    Pages: X, 483 p. 91 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811501692
    DDC: 660.6
    Language: English
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  • 109
    Keywords: Plant physiology. ; Botanical chemistry. ; Plants Development. ; Plant diseases. ; Plant Physiology. ; Plant Biochemistry. ; Plant Development. ; Plant Pathology.
    Description / Table of Contents: Studying miRNAs in plants -- Regulation of plant miRNA biogenesis -- Technologies to address plant miRNA functions -- Strategies and resources for the identification of microRNAs in non-model plants -- miRNAs in the formation of epigenetic memory in plants -- miRNAs in plant development -- miRNA regulation of fruit development -- miRNAs in plant embryogenesis -- Emerging of microRNAs as key regulators in plant secondary metabolism -- miRNAs in vascular development -- miRNAs in plant abiotic and biotic stresses -- Regulation of high-temperature stress response by small RNAs -- Role of microRNAs in plant-fungus interactions -- Plant miRNAs regulate innate immunity through diverse mechanisms.
    Abstract: This book summarizes the latest findings on the functions of microRNAs in the regulation of plant development and responses to the surrounding environment. MicroRNAs are an important class of molecules that can be found in diverse groups of organisms, including plants and animals, and the investigation of their roles is a highly dynamic and “hot” research topic. The respective chapters address four main aspects, namely: microRNA investigation and annotation, the regulatory roles of microRNAs in various developmental processes, in response to abiotic factors, and in the context of biotic stress response regulation. Systematically reviewing the most important findings in this field, the book offers an essential guide for undergraduate and graduate students, teachers, and plant science researchers. Due to the potential applications of microRNAs in crop breeding and plant protection, it also represents a valuable resource for scientists in academia and the private sector alike. .
    Type of Medium: Online Resource
    Pages: XXI, 238 p. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030357726
    Series Statement: Concepts and Strategies in Plant Sciences,
    DDC: 571.2
    Language: English
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  • 110
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Stem cells. ; Regenerative medicine. ; Medical genetics. ; Biotechnology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering. ; Clinical Genetics. ; Chemical Bioengineering.
    Description / Table of Contents: Application of iPSC to modelling of respiratory diseases -- Gene editing in human pluripotent stem cells: recent advances for clinical therapies -- Vascular wall as source of stem cells able to differentiate into endothelial cells -- Physiological and therapeutic roles of neuropeptide Y on biological functions -- Rho signaling-directed YAP/TAZ regulation encourages 3D spheroid colony formation and boosts plasticity of Parthenogenetic Stem Cells -- Transamniotic Stem Cell Therapy -- Regenerative medicine: Injectable cell-based therapeutics and approved products -- Stem Cell Therapy for Hepatocellular Carcinoma: Future Perspectives -- Potential of tribological properties of metalnanomaterials in biomedical applications -- The impact of the low frequency of the electromagnetic field on human.
    Abstract: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the seventh volume of a continuing series Chapter “Application of iPSC to Modelling of Respiratory Diseases” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: VIII, 153 p. 30 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030378455
    Series Statement: Cell Biology and Translational Medicine, 1237
    DDC: 571.6
    Language: English
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  • 111
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Nanotechnology. ; Cancer. ; Stem cells. ; Diseases. ; Biotechnology. ; Nanotechnology. ; Cancer Biology. ; Stem Cell Biology. ; Diseases.
    Description / Table of Contents: Chapter 1.Current Advances in Nanotechnology and Medicine -- Chapter 2. Least Explored Small Wonders: Nano-biotechnology -- Chapter 3. Modern Approaches in Nanomedicine for neuroAIDS and CNS drug delivery -- Chapter 4. Nanobiotechnology: Paving the way to personalized medicine -- Chapter 5. Nanomedicine in cancer stem cell therapy -- Chapter 6. Nanobiosensor: Current Trends and Applications -- Chapter 7. Transition Metal Oxide Nanoparticles: A New Horizon in Cancer Treatment -- Chapter 8. Nanomedicine meets microRNA expression and function in prostate cancer -- Chapter 9. Biomedical applications of Viral Nanoparticles in vaccine therapy -- Chapter 10. HIV: Biology to Nanomedicine -- Chapter 11. Current Advances in Phage Inspired Nanocarriers Based Therapy -- Chapter 12. Nanophytotherapeutic potential of Essential Oils against Candida infections -- Chapter 13. Molecular tests for the Diagnosis of Tuberculosis: Nanodiagnostics Approaches -- Chapter 14. Molecular Mechanisms of drug resistance in Mycobacterium tuberculosis: Role of nanoparticles against Multi-Drug Resistant tuberculosis (MDR-TB) -- Chapter 15. Nano-Mass spectrometry (nano-MS) based lipidomics -- Chapter 16. Techniques to understand Mycobacterial Lipids and use of Lipid Based Nanoformulations for Tuberculosis Management -- Chapter 17. Recent trends and challenges in Patches for cardiac tissue reengineering: role of Nanomaterials -- Chapter 18. Cyclic dinucleotides: Big roles of small molecules and its role in nanotechnology and medicine -- Chapter 19. Antibodies: Biology to Therapeutics and its role in nanomedicine -- Chapter 20. Nanotoxicology in Medicine -- Chapter 21. Antibody-targeted nanoparticles for cancer treatment -- Chapter 22. Nanoparticle mediated combined photothermal and photodynamic therapy -- Chapter 23. Nanotechnology based devices and its applications in medicine- Chapter 24. Opportunities in clinical translation and commercialization of nanomedicine. .
    Abstract: This book provides a comprehensive overview of the recent trends in various Nanotechnology-based therapeutics and challenges associated with its development. Nanobiotechnology is an interdisciplinary research that has wide applications in the various fields of biomedical research. The book discusses the various facets of the application of Nanotechnology in drug delivery, clinical diagnostics, Nanomedicine and treatment of infectious and chronic diseases. The book also highlights the recent advancements on important devices and applications that are based on Nanotechnology in medicine and brief the regulatory and ethical issues related to nanomedical devices. It also reviews the toxicological profile of various nanomaterials and emphasizes the need for safe nanomaterials for clinical use. Finally, the book discusses the recent developments of potential commercial applications of Nanotechnology. .
    Type of Medium: Online Resource
    Pages: XX, 517 p. 90 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789813298989
    DDC: 660.6
    Language: English
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  • 112
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Parasitology. ; Internal medicine. ; Microbiology. ; Parasitology. ; Internal Medicine. ; Microbiology.
    Description / Table of Contents: Chapter 1. Parasite taxonomy, Classification of Zoonoses -- Chapter 2. Host Parasite Relationship and Spectrum of Clinical Manifestations -- Chapter 3. Parasitic Immunology -- Chapter 4. Parasite Genomics -- Chapter 5. Parasite Proteomics -- Chapter 6. Epidemiology of Parasitic Zoonoses -- Chapter 7. Diagnosis of Parasitic Zoonoses -- Chapter 8. Treatment and Management of Parasitic Zoonoses -- Chapter 9. Drug Resistance in Parasites -- Chapter 10. Zoonotic potential of Bioterrorism -- Chapter 11. Prevention, Surveillance, and Control of Parasitic Zoonoses -- Chapter 12. Toxoplasmosis -- Chapter 13. Giardiasis -- Chapter 14. Leishmaniasis -- Chapter 15. Trypanosomiasis -- Chapter 16. Malaria -- Chapter 17. Babesiosis -- Chapter 18. Cryptosporidiosis -- Chapter 19. Sarcocystosis. -- Chapter 20. Balantidiasis -- Chapter 21. Schistosomiasis -- Chapter 22. Fascioliasis -- Chapter 23. Fasciolopsiasis -- Chapter 24. Paragonomiasis -- Chapter 25. Echinostomiasis -- Chapter 26. Ophistorchiasis -- Chapter 27. Clonerchiasis -- Chapter 28. Heterophyes, Metagonimus, Dirocelium, Trogolotrema, and Watsonia infections -- Chapter 29. Diphyllobothriasis -- Chapter 30. Taeniasis -- Chapter 31. Echinococciasis -- Chapter 32. Sparganosis -- Chapter 33. Dipyllidiosis -- Chapter 34. Hymenolepsiasis -- Chapter 35. Coenurosis -- Chapter 36. Bertiella, Inermicapsifer, and Raillietinal infections -- Chapter 37. Trichinellosis -- Chapter 38. Dracunculiasis -- Chapter 39. Capillariasis -- Chapter 40. Strongyloidosis -- Chapter 41. Ancylostomiasis -- Chapter 42. Ascariasis -- Chapter 43. Dioctophymasis -- Chapter 44. Angiostrongylus and Trichostrongylus infections -- Chapter 45. Toxocariasis -- Chapter 46. Anisakiasis -- Chapter 47. Gnathostomiasis -- Chapter 48. Dirofilariasis -- Chapter 49. Thelaziasis -- Chapter 50. Gongylonemiasis -- Chapter 51. Termidens infections -- Chapter 52. Larva Migrans -- Chapter 53. Oesophagostomum and Mammomonogamus infections -- Chapter 54. Pentastomiasis -- Chapter 55. Scabies -- Chapter 56. Myiasis -- Chapter 57. Tungiasis -- Chapter 58. Ticks, Mites, Fleas -- Chapter 59. Allergenic MitesInfestations caused by Ectoparasites.
    Abstract: This textbook, which is the first volume in the series Microbial Zoonoses, provides a comprehensive overview of the diagnosis, treatment and control of zoonotic parasitic diseases. The book is divided into two sections; the first section discusses the classification of parasitic zoonoses and includes general information on the diagnosis, treatment, epidemiology, prevention, and control of parasitic zoonoses. It also describes the biological features of these organisms, host-parasite interactions, and the disease spectrum, as well as the importance of public health control measures, such as surveillance, and prophylactic measures in controlling these diseases. The second section explores the important zoonotic diseases caused by ectoparasites, protozoan and helminths parasites. It also reviews the life cycle, pathogenesis, pathology, immunology and clinical manifestations, modern diagnostic methods, treatment regimen, prevention, control, and epidemiology of these parasites. Cutting across the disciplines, this book serves as a guide to postgraduate students, faculty members, public health experts, and medical administrators who are interested in the management of these parasitic zoonotic infections.
    Type of Medium: Online Resource
    Pages: XXVII, 655 p. 239 illus., 219 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811672040
    Series Statement: Microbial Zoonoses,
    DDC: 571.999
    Language: English
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  • 113
    Keywords: Agriculture. ; Botany. ; Agriculture. ; Plant Science.
    Description / Table of Contents: Preface -- Part I: Leaves -- Chapter 1. Advances in Chicory (Cichorium intybus L.) Breeding Strategies (Laila Aldahak, Khaled F. M. Salem, Salih H. F. Al-Salim, and Jameel M. Al-Khayri) -- Chapter 2. Chinese Cabbage (Brassica rapa L. var. pekinensis) Breeding: Application of Molecular Technology (Takumi Okamoto, Xiaochun Wei, Hasan Mehraj, Mohammad Rashed Hossain, Ayasha Akter, Naomi Miyaji, Yoshinobu Takada, Jong-In Park, Ryo Fujimoto, Ill-Sup Nou, and Masao Watanabe) -- Chapter 3. Breeding Advances and Prospects in Rocket Salad (Eruca vesicaria ssp. sativa Mill.) Cultivation (Pasquale Tripodi, Paula Santos Coelho, and Carla Guijarro-Real) -- Chapter 4. Spring Onion (Allium fistulosum L.) Breeding Strategies (Fatimah Kayat, Ahmed Mahmood Ibrahim, and Arifullah Mohammed) -- Chapter 5. Water Spinach (Ipomoea aquatica Forsk.) Breeding (Moumita Gangopadhyay, Anup Kumar Das, Subhendu Bandyopadyay, and Samanwita Das) -- Chapter 6. Watercress (Nasturtium officinale R. Br.) Breeding (Mohammadreza Hassandokht, Sajad Jafari, and Raheleh Ebrahimi) -- Part II: Flowerheads and Green Pods -- Chapter 7. Advances in Cauliflower (Brassica oleracea var. botrytis L.) Breeding, with Emphasis on India (Pritam Kalia and Shrawan Singh) -- Chapter 8. Globe Artichoke (Cynara cardunculus var. scolymus L.) Breeding (Fernando López-Anido and Eugenia Martin) -- Chapter 9. Breeding Strategies of Garden Pea (Pisum sativum L.) (Amal M.E. Abdel Hamid and Khaled F.M. Salem) -- Chapter 10. Genetic Improvement of Yardlong Bean (Vigna unguiculata (L.) Walp. ssp. sesquipedalis (L.) Verdc.) (Pidigam Saidaiah, Thuraga Vishnukiran, Someswar Rao Pandravada, Natarajan Sivaraj, Adimulam Srivani, Amarapalli Geetha, Nimmarajula Srinivas, and Venkateswaran Kamala) -- Part III: Mushrooms -- Chapter 11. Enoki Mushroom (Flammulina velutipes (Curtis) Singer) Breeding (Ved P. Sharma, Anupam Barh, Rakesh Kumar Bairwa, Sudheer K. Annepu, Babita Kumari and Shwet Kamal) -- Chapter 12. Shiitake Mushroom (Lentinula edodes (Berk.) Sing.) Breeding in China (Quanju Xiang, Bilal Adil, Qiang Chen, Yunfu Gu, Xianfu Zeng, and Xinzhu Li) -- Part IV: Truffles -- Chapter 13. Desert Truffles (Terfezia spp.) Breeding (Asunción Morte, Francisco Arenas, José E. Marqués-Gálvez, Alberto Andrino, Ángel L. Guarnizo, Almudena Gutiérrez, Luis Miguel Berná, Manuela Pérez-Gilabert, Antonio Rodríguez, and Alfonso Navarro-Ródenas) -- Chapter 14. Enhancing White Truffle (Tuber magnatum Picco and T. borchii Vittad.) Cultivation through Biotechnology Innovation (Alessandra Zambonelli, Mirco Iotti, Federico Puliga, and Ian R. Hall).
    Abstract: Plant breeders and geneticists are under constant pressure to sustain and expand food production by using innovative breeding strategies and introducing minor crops, which are well adapted to marginal lands, provide a source of nutrition, and have abiotic and biotic stress tolerance, to feed an ever-increasing human population. The basic concept of this book is to examine the use of innovative methods, augmenting traditional plant breeding, towards the improvement and development of new crop varieties, under the increasingly limiting environmental and cultivation factors, to achieve sustainable agricultural production and enhanced food security. Three volumes of the book series Advances in Plant Breeding Strategies were published in 2015, 2016 and 2018, respectively: Volume 1. Breeding, Biotechnology and Molecular Tools; Volume 2. Agronomic, Abiotic and Biotic Stress Traits and Volume 3. Fruits. In 2019, the following four volumes were published: Volume 4. Nut and Beverage Crops, Volume 5. Cereals, Volume 6. Industrial and Food Crops and Volume 7. Legumes. Recent volumes published in 2021 include: Volume 8. Vegetable Crops: Bulbs, Roots and Tubers, Volume 9. Vegetable Crops: Fruits and Young Shoots and Volume 10. Vegetable Crops: Leaves, Flowerheads, Green Pods, Mushrooms and Truffles. This Volume 10, subtitled Vegetable Crops: Leaves, Flowerheads, Green Pods, Mushrooms and Truffles, consists of 14 chapters focusing on advances in breeding strategies using both traditional and modern approaches for the improvement of individual vegetable crops. Chapters are arranged in 4 parts according to the edible vegetable parts. Part I: Leaves - Chicory, Chinese cabbage, Rocket salad, Spring onion, Water spinach and Watercress; Pat II: Flowerheads and Green Pods - Cauliflower, Globe artichoke, Garden pea and Yardlong bean; Part III: Mushrooms - Enoki mushroom and Shiitake mushroom; Part IV: Truffles - Desert truffles and White truffle. Each chapter comprehensively reviews the contemporary literature on the subject and reflects the experiences of the authors. Chapters are written by internationally-reputable scientists and subjected to a review process to assure quality presentation and scientific accuracy. Each chapter begins with an introduction covering related backgrounds and provides in-depth discussion of the subject supported with high-quality color photos, illustrations and relevant data. The chapter concludes with recommendations for future research directions, a comprehensive list of pertinent references to facilitate further reading, and appendixes of genetic resources and concerned research institutes. This book series is a valuable resource for advanced students, researchers, scientists, commercial producers and seed companies as well as consultants and policymakers interested in agriculture, particularly in modern breeding technologies.
    Type of Medium: Online Resource
    Pages: XVII, 540 p. 98 illus., 76 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030669690
    DDC: 630
    Language: English
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  • 114
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cytology. ; Bioinformatics. ; Imaging systems in biology. ; Cell Biology. ; Computational and Systems Biology. ; Biological Imaging.
    Description / Table of Contents: Introduction -- Batch Processing Methods in ImageJ -- Python: Data Handling, Analysis and Plotting -- Building a Bioimage Analysis Workflow Using Deep Learning -- GPU-Accelerating ImageJ Macro Image Processing Workflows Using CLIJ -- How to Do the Deconstruction of Bioimage Analysis Workflows: A Case Study with SurfCut -- i.2.i. with the (Fruit) Fly: Quantifying Position Effect Variegation in Drosophila Melanogaster -- A MATLAB Pipeline for Spatiotemporal Quantification of Monolayer Cell Migration.
    Abstract: This open access textbook aims at providing detailed explanations on how to design and construct image analysis workflows to successfully conduct bioimage analysis. Addressing the main challenges in image data analysis, where acquisition by powerful imaging devices results in very large amounts of collected image data, the book discusses techniques relying on batch and GPU programming, as well as on powerful deep learning-based algorithms. In addition, downstream data processing techniques are introduced, such as Python libraries for data organization, plotting, and visualizations. Finally, by studying the way individual unique ideas are implemented in the workflows, readers are carefully guided through how the parameters driving biological systems are revealed by analyzing image data. These studies include segmentation of plant tissue epidermis, analysis of the spatial pattern of the eye development in fruit flies, and the analysis of collective cell migration dynamics. The presented content extends the Bioimage Data Analysis Workflows textbook (Miura, Sladoje, 2020), published in this same series, with new contributions and advanced material, while preserving the well-appreciated pedagogical approach adopted and promoted during the training schools for bioimage analysis organized within NEUBIAS – the Network of European Bioimage Analysts. This textbook is intended for advanced students in various fields of the life sciences and biomedicine, as well as staff scientists and faculty members who conduct regular quantitative analyses of microscopy images.
    Type of Medium: Online Resource
    Pages: X, 212 p. 265 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030763947
    Series Statement: Learning Materials in Biosciences,
    DDC: 571.6
    Language: English
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  • 115
    Keywords: Plant anatomy. ; Stress (Physiology). ; Plants. ; Plant physiology. ; Plant ecology. ; Plants Development. ; Agriculture. ; Plant Anatomy and Morphology. ; Plant Stress Responses. ; Plant Physiology. ; Plant Ecology. ; Plant Development. ; Agriculture.
    Description / Table of Contents: Crosstalk between autophagy and hormones for abiotic stress tolerance in plants -- Abscisic acid and plant response under adverse environmental conditions -- Auxins and plant response to adverse environmental conditions -- Jasmonic acid for sustainable plant growth and production under adverse environmental conditions -- Salicylic acid for vigorous plant growth and enhanced yield under harsh environment -- Strigolactones for sustainable plant growth and production under adverse environmental conditions -- Polyamines for sustainable plant growth and production under adverse environmental conditions -- Plant performance and defensive role of proline under environmental stress -- Plant performance and defensive role of β-amino butyric acid under environmental stress -- Plant performance and defensive role of γ-gamma amino butyric acid under environmental stress -- Nitric oxide: A key modulator of plant responses under environmental stress -- Functions of hydrogen sulfide in plant regulation and response to abiotic stress -- Silicon and plant responses under adverse environmental conditions -- Nanofertilizers as tools for plant nutrition and plant biostimulation under adverse environment -- Biostimulants and plant response under adverse environmental conditions: a functional interplay -- Biofertilizers-mediated sustainable plant growth and production under adverse environmental conditions -- Seed priming: A cost-effective strategy to impart abiotic stress tolerance -- Significance of cyanobacteria in soil-plant system and for ecological resilience -- Phytomicrobiome community: An agrarian perspective -- Adverse environment and pest management for sustainable plant production -- Eco-friendly approaches of using weeds for sustainable plant growth and production.
    Abstract: Global climate change is bound to create a number of abiotic and biotic stresses in the environment, which would affect the overall growth and productivity of plants. Like other living beings, plants have the ability to protect themselves by evolving various mechanisms against stresses, despite being sessile in nature. They manage to withstand extremes of temperature, drought, flooding, salinity, heavy metals, atmospheric pollution, toxic chemicals and a variety of living organisms, especially viruses, bacteria, fungi, nematodes, insects and arachnids and weeds. Incidence of abiotic stresses may alter the plant-pest interactions by enhancing susceptibility of plants to pathogenic organisms. These interactions often change plant response to abiotic stresses. Plant growth regulators modulate plant responses to biotic and abiotic stresses, and regulate their growth and developmental cascades. A number of physiological and molecular processes that act together in a complex regulatory network, further manage these responses. Crosstalk between autophagy and hormones also occurs to develop tolerance in plants towards multiple abiotic stresses. Similarly, biostimulants, in combination with correct agronomic practices, have shown beneficial effects on plant metabolism due to the hormonal activity that stimulates different metabolic pathways. At the same time, they reduce the use of agrochemicals and impart tolerance to biotic and abiotic stress. Further, the use of bio- and nano-fertilizers seem to hold promise to improve the nutrient use efficiency and hence the plant yield under stressful environments. It has also been shown that the seed priming agents impart stress tolerance. Additionally, tolerance or resistance to stress may also be induced by using specific chemical compounds such as polyamines, proline, glycine betaine, hydrogen sulfide, silicon, β-aminobutyric acid, γ-aminobutyric acid and so on. This book discusses the advances in plant performance under stressful conditions. It should be very useful to graduate students, researchers, and scientists in the fields of botanical science, crop science, agriculture, horticulture, ecological and environmental science.
    Type of Medium: Online Resource
    Pages: XIV, 606 p. 54 illus., 51 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030785215
    DDC: 571.32
    Language: English
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  • 116
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Food science. ; Food Analysis. ; Chemistry. ; Sustainability. ; Food Engineering. ; Food Science. ; Food Chemistry. ; Sustainability.
    Description / Table of Contents: Part I: Introduction -- 1.Sustainability in food science and food industry: where are we now? – Viewpoints of the EFFoST Working Group on Sustainable Food Systems -- 2. Innovative processing: from raw material (culture), harvesting, post harvesting, processing, and applications -- Part II: Mechanism of action of nonthermal processing technologies (NTP) -- 3. Fundamental mechanisms of action -- 4. Electro-technologies: pulsed electric fields, cold plasma, radio-frequency and oscillating magnetic fields, electrohydrodynamic processing, electron beam processing and ionizing radiation -- 5. Pressure-based technologies: high pressure processing; supercritical and subcritical fluid processing -- 6. Mechanical technologies: ultrasound, and hydrodynamic cavitation -- 7. Non-electro-technologies: gamma rays, UV light, pulsed light, ozonation, photodynamic and membrane processing -- 8. Non-electro-technologies: gamma rays, UV light, ozone, photodynamic and membrane processing -- Part 3: Implementation of novel nonthermal technologies in agri-food-bio sciences -- 9. Nonthermal Processing Technologies: Synergies and new applications in food engineering -- 10. Implementation of novel nonthermal plasma air cleaner in a plant factory -- 11. LED-based photosensitization – a prospect for visible light-driven nonthermal fresh produce sanitation -- 12. Electrospinning Technology: Its Process Conditions and Food Packaging Applications -- 13. Application of encapsulation technology in the agri-food sector -- Part 4. Nonthermal processing legislation -- 14. Overview of legislation across the globe, diagnostics and standards which provide a legal and regulatory framework in which NTP is used worldwide -- 15. Current technology readiness levels (TRL) of nonthermal technologies and research gaps for improved process control and integration into existing production lines -- 16. Industry implementation (scale-up): Clients’ experience towards understanding of how regulations are affecting novel product development -- 17. Supercritical fluids as a tool for sustainable manufacturing of added value products -- Part 5 Mechanisms of validation of nonthermal processes in biomaterials and agri-food applications -- 18. Current validation of NTP technologies and overview of their current and potential implementation in the production chain including agri-food wastes -- Part 6. Sustainable perspective of nonthermal technologies -- 19. New product development from marine sources and side streams valorization using nonthermal processing technologies -- 20. Efficient production of functional and bioactive compounds and foods for use in food, pharma, cosmetic and other industries -- 21. Decontamination of fruit juices by combination of high intensity pulsed light and other nonthermal technologies -- 22. Food-On-A-Chip: Relevance of Microfluidics in food processing -- Part 7. Food waste management and sustainable parameters analysis -- 21. Analysis and comparison of environmental impacts of nonthermal food technologies -- 22. Emerging non-thermal processing of food waste and by-products for sustainable food systems - selected cases -- 23. Strategies for commercializing scientific results and combining separate processes into complex technologies -- 24 Sustainable processing through efficient use of energy and minimizing waste production -- 25. Food Safety and Security (HACCP and HAZOP) for Consumers and Workers (Nonthermal Technologies and their use) -- Part 8. Success stories of industrial implementation of nonthermal technologies -- 26.: Innovative success stories on commercial non-thermal technologies - interviews of major food industries working in this area. .
    Abstract: This book addresses important questions on the legislation, regulations, sustainability, technology transfer, safety of biomaterials and mechanism of action of nonthermal processing on the molecular level of biomaterials and its impact on health. The chapters take an interdisciplinary approach that is of interest to specialists from engineering, physics, chemistry, agriculture, life sciences and beyond, with a focus on further development of existing and new applications of nonthermal processing and their combination with other methods in the processing of biomaterials, agriculture, biotechnology and the re-use of waste and by-products. Nonthermal Processing in Agri-Food-Bio Sciences: Sustainability and Future Goals aims to boost further developments and applications of nonthermal technologies to develop healthier products, to ensure consumer approval for these innovative technologies and to improve the sustainability of biomaterials production. The industrial application of nonthermal processing has led to an increase in innovative value products and the overall improvement of production capacity. Nonthermal processes use less energy and chemicals, reduce processing times, have less environmental impact, produce less waste and have the potential for industrial scale-up and a return-on-investment in under 5 years. According to The United Nations and the 2030 Agenda for Sustainable Development, 17 goals should be incorporated within development projects, and researchers are starting to use novel techniques to meet them. In covering the fundamental engineering theories underlying nonthermal processing, this book will aid in this mission. The book overviews the advantages and disadvantages of novel technologies, over to sustainability goals to correct steps for the scale-up and return on investment. The book includes the chemistry and physics of nonthermal processing technologies, dedicated to specialists and researchers from a wide range of subject areas. Interdisciplinary scientists and engineers, sustainability experts can use this text to aid in their work in green technologies.
    Type of Medium: Online Resource
    Pages: VIII, 791 p. 124 illus., 74 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030924157
    Series Statement: Food Engineering Series,
    DDC: 664
    Language: English
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  • 117
    Keywords: Neurosciences. ; Animal culture. ; Veterinary medicine. ; Neuroscience. ; Animal Science. ; Veterinary Science.
    Description / Table of Contents: Rodents -- Carnivores -- Sheep and goats -- Swine -- Rabbits -- Bovines -- Non-human primates -- Humans -- Squirrels.
    Abstract: Modern neuroscience has presented new opportunities for exploring the molecular and neural mechanisms controlling specific social responses. This book reviews insights into the neural circuits underlying a particularly fascinating form of social interaction, parental behavior. This book presents a detailed review of maternal and paternal behavior of particular mammalian species. It offer neuroscientists a spectrum of specific mammals that can be used as experimental models to explore particular topics on the functions of the nervous system. It shows that results coming from the laboratory can be translated into useful information for raising mammals on the farm, and it stimulates biologists to gain insights into the underpinnings of the complex mechanisms governing mammalian behavior in the wild. It also discusses the implications of this research for human parental behavior. .
    Type of Medium: Online Resource
    Pages: V, 309 p. 45 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783030977627
    Series Statement: Advances in Neurobiology, 27
    DDC: 612.8
    Language: English
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  • 118
    Keywords: Biotechnology. ; Microtechnology. ; Microelectromechanical systems. ; Enzymology. ; Nanotechnology. ; Biotechnology. ; Microsystems and MEMS. ; Enzymology. ; Nanotechnology.
    Description / Table of Contents: Immobilization: Then and Now -- Cell immobilization strategies for tissue engineering: Recent trends and future perspectives -- Strategies and advancement in growth factor immobilizable ECM for tissue engineering -- Prospects Of Cell Immobilization In Cancer Research And Immunotherapy -- Nano systems for repairing retinal degeneration -- Systemic drug delivery to the posterior segment of the eye: Overcoming blood-retinal barrier through smart drug design and nanotechnology -- The effects of irradiation with cold atmospheric-pressure plasma on cellular function -- Immobilization of biomolecules on plasma functionalized surfaces for biomedical applications -- A wide portray of Upconversion-nanoparticles: surface modification for bio-applications -- Advances in Amphiphilic Assemblies and its Immobilization in Room Temperature Supercooled Matrices. .
    Abstract: This book delves into the field of immobilizing biologically active and non-active molecules. It discusses the designing strategy of immobilization and the current state-of-the-art applications for advancing biomedical, agricultural, environmental and industrial practices. It focuses on aspects ranging from fundamental principles to current technological advances at multi-scale levels (macro, micro, and nano) which are suitable for cell, enzyme, and nano-catalyst based applications. Written by experts from across the globe, the contents deal with illustrated examples of molecular and cellular interactions with materials/scaffolds and discussions on factors that can affect the functionality and yield of the process. With its discussions on material science, design of delivery vehicles, separation science, additive manufacturing, agriculture and environmental science, this book will be a useful reference for researchers across multiple disciplines.
    Type of Medium: Online Resource
    Pages: X, 666 p. 143 illus., 126 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811579981
    Series Statement: Gels Horizons: From Science to Smart Materials,
    DDC: 660.6
    Language: English
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  • 119
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Biophysics. ; Cell interaction. ; Cytology. ; Cancer Microenvironment. ; Mechanobiological Cell Signaling. ; Cell Biology. ; Cancer Biology.
    Description / Table of Contents: Neuregulin signaling in the tumor microenvironment -- HGF/c-Met signalling in the tumor microenvironment -- Eph/ephrin signaling in the tumor microenvironment -- Src signaling in cancer and tumor microenvironment -- Purinergic signaling within the tumor microenvironment -- TGFβ signalling in the tumor microenvironment -- Wnt Signaling in the Tumor Microenvironment -- Lysophospholipid Signalling and the Tumour Microenvironment -- Adenosine signaling in the tumor microenvironment -- Androgen signaling in the tumor microenvironment -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on how different signaling pathways are important in the tumor microenvironment. Multiple signaling pathways are covered, including Src, Neuregulin, Adenosine, TGFβ, Androgen, Wnt, and more. Taken alongside its companion volumes, these books update us on what we know about various aspects of the tumor microenvironment as well as future directions. Tumor Microenvironment: Signaling Pathways – Part B is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
    Type of Medium: Online Resource
    Pages: XIII, 191 p. 31 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030471897
    Series Statement: Advances in Experimental Medicine and Biology, 1270
    DDC: 571.978
    Language: English
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  • 120
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Biochemistry. ; Genetics. ; Biomedical Research. ; Biochemistry. ; Genetics and Genomics.
    Description / Table of Contents: Central dogma of molecular biology -- Impact of chromatin structure -- Epigenetics enables gene expression -- Gene regulation in the context of nuclear architecture -- Core promoter -- TATA box and other core promoter elements -- Genome-wide core promoter identification -- TFIID and Mediator as paradigms of multi-protein complexes -- Site-specific transcription factors and their domains -- Classification of transcription factors -- Activation of transcription factors -- Programing cellular differentiation by transcription factors -- Inflammatory signaling via NF-KB -- Sensing cellular stress via p53 -- The nuclear receptor superfamily -- Molecular interactions of nuclear receptors -- Physiological role of nuclear receptors -- Next-generation sequencing -- Gene regulation in the context of Big Biology -- Exploring genome-wide transcription factor binding -- Integrating epigenome-wide datasets -- Cytosines and their methylation -- Histone modifications -- Gene regulation via chromatin modifiers -- Sensing energy metabolism via chromatin modifiers -- Epigenetics and chromatin -- Genome-wide understanding of epigenetics -- CTCF and genetic imprinting -- Epigenetics in health and disease -- Nucleosome positioning at promoters -- Chromatin remodeling -- Transcriptional dynamics in the presence of chromatin -- Organization of the nucleus -- Non-coding RNAs -- miRNAs and their regulatory potential -- Long ncRNAs -- Enhancer RNAs.
    Abstract: This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of gene expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. Th is pivotal role for the regulation of gene expression makes this textbook essential reading for students of all the biomedical sciences, in order to be better prepared for their specialized disciplines. A complete understanding of transcription factors and the processes that alter their activity is a major goal of modern life science research. The availability of the whole human genome sequence (and that of other eukaryotic genomes) and the consequent development of next-generation sequencing technologies have significantly changed nearly all areas of the biological sciences. For example, the genome-wide location of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is the description of the post-genome understanding of gene regulation.
    Type of Medium: Online Resource
    Pages: XVI, 149 p. 71 illus., 70 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030523213
    DDC: 610.72
    Language: English
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  • 121
    Keywords: Phylogeny. ; Biology Technique. ; Gene expression. ; Bioinformatics. ; Phylogenetics. ; Gene Expression Analysis. ; Bioinformatics.
    Description / Table of Contents: Introduction to phylogenetic trees -- A divergence time story: the rise and fall of the molecular clock -- Estimating phylogenetic trees -- Estimating divergence times -- Estimating common ancestors -- Testing theories of molecular evolution -- Recommendations for further reading -- Appendix A: Intermittent point processes -- Appendix B: Poisson processes with Lévy-stable substitution rates.
    Abstract: This book serves as a brief introduction to phylogenetic trees and molecular evolution for biologists and biology students. It does so by presenting the main concepts in a variety of ways: first visually, then in a history, next in a dice game, and finally in simple equations. The content is primarily designed to introduce upper-level undergraduate and graduate students of biology to phylogenetic tree reconstruction and the underlying models of molecular evolution. A unique feature also of interest to experienced researchers is the emphasis on simple ways to quantify the uncertainty in the results more fully than is possible with standard methods.
    Type of Medium: Online Resource
    Pages: XIII, 106 p. 21 illus., 14 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031119583
    Series Statement: SpringerBriefs in Systems Biology,
    DDC: 576.88
    Language: English
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  • 122
    Keywords: Freshwater ecology. ; Marine ecology. ; Conservation biology. ; Ecology . ; Geography. ; Environment. ; Power resources. ; Freshwater and Marine Ecology. ; Conservation Biology. ; Regional Geography. ; Environmental Sciences. ; Natural Resource and Energy Economics.
    Description / Table of Contents: Intro: Navigating Patagonian freshwaters- and this book -- 1: Are freshwaters wetlands? -- 2: Patagonian Andean lakes and climate change -- 3: Current state and recent changes of glaciers in the Patagonian Andes (35 °S to 55°S) -- 4: Biogeographical patterns of Patagonian freshwater microbiota -- 5: Extreme freshwater ecosystems from Patagonia: The Copahue-Agrio system -- 6: Mercury in aquatic systems of North Patagonia: sources, processes and trophic transfer -- 7: Diversity patterns across aquatic communities from peat bogs -- 8: Hydrologic Systems, water uses and emerging conflicts around freshwater availability in Patagonia -- 9: Land-use effects on aquatic ecosystems: An overview of environmental impacts and tools for ecological assessment -- 10: Patagonian wetlands: vertientes, vegas, mallines,turberas and lagunas -- 11: Fish and fisheries of the Patagonian steppe -- 12: Invasive species: The case of Didymosphenia geminata in Neuquén Province -- 13: Influence of the fish introduction in lakes of the arid Patagonia -- 14: Patagonian cultural limnology: knowledge and water management in Mapuche rural communities -- 15: Political Ecology, water valoration and Water Law deliberation in the Province of Tierra del Nacional de Tierra del Fuego -- 16: Freshwater systems in protected areas in Patagonia -- 17: Amphibians and waterbirds as bridges to conserve aquatic and terrestrial habitat in Patagonia -- 18: Integrated long term conservation strategies to recover the critically endangered Hooded Grebe (Podiceps gallardoi),an endemic waterbird of Austral Patagonia -- Conclusion: Reaching out for the UNDP Sustainable Development Goals in Patagonia.
    Abstract: The Freshwaters of Patagonia adopts a socioecological approach, in which experts from across Patagonia review recent, scientifically rigorous literature and data of their own, thus synthesizing the current knowledge directly relevant to understand the present state and future trends of icefields, freshwater and wetland ecosystems in this region. The book’s organization into three parts provides a studied and comprehensive view on the patterns and processes of the various ecosystems in Patagonia, and describes the sociological aspects of freshwater ecosystems, as well as characterizes the conservation of the freshwater and wetland ecosystems, in Patagonia. The chapters offer a broad, state-of-the-art overview of the current status of glaciers, freshwater and wetland ecosystems of this region, as well as studies of both local and large scale biodiversity patterns, and study cases of extreme and naturally polluted environments.The volume concludes with the current status of Patagonian freshwaters, and discusses the scientific, legal and administrative tools aimed at their sustainable management within the framework of the UNEP Sustainable Development Goals 2030 Agenda. A broad audience of students, scientists, engineers, environmental managers, and policy makers will be interested in this volume.
    Type of Medium: Online Resource
    Pages: XI, 541 p. 104 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031100277
    Series Statement: Natural and Social Sciences of Patagonia,
    DDC: 577.6
    Language: English
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  • 123
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medical genetics. ; Medicinal chemistry. ; Nanomedicine. ; Cancer Treatment. ; Medical Genetics. ; Medicinal Chemistry. ; Nanomedicine and Nanotoxicology. ; Cancer Therapy.
    Description / Table of Contents: The Democratization of RNA Therapeutics -- Supramolecular Strategies for mRNA Delivery -- In Vitro-Transcribed mRNAs as a New Generation of Therapeutics in the Dawn of 21st Century: Exploitation of Peptides as Carriers for their Intracellular Delivery -- Effective Delivery of mRNA Therapeutics and Vaccines Using Lipid Nanoparticles -- Messenger RNA Therapeutics -- Formulation, Delivery and Application of mRNA Therapeutics In Respiratory Diseases -- Clinical Applications of mRNA Formulated In Lipid Nanoparticles -- Preparation of Messenger RNA Loaded Nanomedicine Applied on Tissue Engineering And Regenerative Medicine -- Lipid Nanoparticle-Mediated Delivery of mRNA Therapeutics: Immune Activation By Ionizable Cationic Lipids -- Adjuvants, the Elephant in the Room for RNA Vaccines -- Addressing Skin with Modified mRNA Constructs for Novel Therapies -- mRNA-Based Cancer Immunotherapies -- From Bench to Bedside: The Journey of an mRNA Drug Candidate Into a Medicine -- Synthetic mRNA Gene Therapies for Chronic HBV Infection -- Delivery Vehicles for Self-Amplifying RNA -- Delivery Technologies of mRNA Vaccines -- Nanosystems: The Key in Formulations of mRNA for Several Pathologies -- Messenger RNA Nanoformulation For Cancer Vaccine -- Preparation of Synthetic mRNAs for In Vivo Applications – Overview and Considerations -- Messenger RNA for Prophylaxis -- Nuclear Export of mRNA with Disease Pathogenesis and Therapeutic Potentials -- Messenger RNA Therapeutics: Start of a New Era in Medicine -- mRNA Delivery Technologies for Therapeutic Applications.
    Abstract: This book focuses on the fundamentals and applications of messenger RNA (mRNA)-based therapeutics and discusses the strengths and key challenges of this emerging class of drugs. In the past 30 years, extensive research and technological development in many areas have contributed to the emergence of in vitro transcribed mRNA as a therapeutic that has now reached clinical testing. Formulations that protect the mRNA from nucleases and accelerate its cellular uptake, combined with improvements to the mRNA molecules themselves, have been critical advancements for mRNAs to become viable therapeutics. Though once regarded as a serious impediment, the transient nature of mRNA technology is now considered a major advantage in making mRNA therapies safe and, ultimately, a potential game changer in the field of medicine. This new book in the RNA Technologies series provides a state-of-the-art overview on the emerging field of mRNA therapeutics covering essential strategies for formulation, delivery, and application. It also reviews the promising role in cancer immunotherapy, respiratory diseases, and chronic HBV infection and discusses RNA vaccines in light of the current COVID-19 pandemic. mRNA-based approaches have great potential to revolutionize molecular biology, cell biology, biomedical research, and medicine. Thus, this handbook is an essential resource for researchers in academia and industry contributing to the development of this new area of therapeutics.
    Type of Medium: Online Resource
    Pages: XII, 446 p. 68 illus., 57 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031084157
    Series Statement: RNA Technologies, 13
    DDC: 616.042
    Language: English
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  • 124
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Oncology. ; Immunology. ; Metastasis. ; Cytology. ; Cancer Biology. ; Oncology. ; Immunology. ; Metastasis. ; Cell Biology.
    Description / Table of Contents: Chapter 1. A Systemic View of Metastatic Disease: Inter-organ Crosstalk and Therapeutic Implications -- Part I. Systemic Regulation in Metastatic Disease -- Chapter 2. Systemic Regulation of Metastatic Disease by Extracellular Vesicles and Particles -- Chapter 3. Bone Metastasis: Systemic Regulation and Impact on Host -- Chapter 4. Targeting Metastatic Disease: Challenges and New Opportunities -- Part II. Cachexia: A Debilitating Systemic Effect of Cancer -- Chapter 5. Signaling Pathways That Promote Muscle Catabolism in Cachexia -- Chapter 6. The Role of Interleukin-6 Cytokines in Cancer Cachexia -- Chapter 7. NF-kB Signaling in the Macroenvironment of Cancer Cachexia -- Part III. Therapy-induced Muscle Wasting -- Chapter 8. Therapy-induced Toxicities Associated with the Onset of Cachexia -- Chapter 9. Bone-muscle Crosstalk in Advanced Cancer and Chemotherapy -- Part IV. Preventing and Targeting Cachexia in Cancer -- Chapter 10. New Developments in Targeting Cancer Cachexia -- Chapter 11. Exercise: A Critical Component of Cachexia Prevention and Therapy in Cancer.
    Abstract: This textbook discusses the systemic consequences of cancer, covering a range of topics from tumor-promoting systemic effects to the development of cachexia, as summarized in the introductory chapter 1. Part I of this textbook focuses on tumor-promoting systemic effects and begins with a chapter on how tumor-derived extracellular vesicles and particles lay the foundation for future metastases (Chapter 2). Chapter 3 discusses how metastatic cells that have colonized the bone impact the local bone microenvironment, neighboring muscles, and host physiology. Chapter 4 summarizes the available strategies for targeting metastatic cancer and emphasizes the need to incorporate a systemic view of the disease. Following this overview of the systemic effects of cancer progression, Part II of the textbook discusses cancer-induced cachexia, a debilitating systemic effect of advanced cancer. Chapters 5-7 examine the key signaling pathways (interleukin-6/GP130, NF-kB, and muscle proteolysis) that drive the development of cancer cachexia. Chapters 8 and 9 in Part III of this textbook explore how toxicities from anti-cancer therapy are associated with the onset of cachexia in cancer patients, and provide insight into potential approaches to simultaneously target both cancer and cachexia. Chapters 10 and 11 (Part IV) conclude this textbook by outlining promising approaches for the diagnosis and treatment of cachexia as well as strategies to prevent the development of cachexia through exercise. An understanding of the systemic effects of cancer is essential for the design of effective anti-cancer and anti-cachexia treatment strategies. As such, this textbook provides key information for both students and scientists engaged in cancer research and oncology.
    Type of Medium: Online Resource
    Pages: VI, 203 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031095184
    DDC: 571.978
    Language: English
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  • 125
    Keywords: Human physiology. ; Medical education. ; Premedical education. ; Ultrasonics. ; Human Physiology. ; Medical Education. ; Premedical Education. ; Ultrasonics.
    Description / Table of Contents: Chapter 1: Using Ultrasound to Teach Physiology – An Introduction -- Chapter 2: The Basics of Ultrasound Physics -- Chapter 3: Ultrasound of the Vascular System -- Chapter 4: Ultrasound of the Heart -- Chapter 5: Ultrasound of the Respiratory System -- Chapter 6: Ultrasound of the Gastrointestinal System -- Chapter 7: Ultrasound of the Urinary System -- Chapter 8: Ultrasound of the Musculoskeletal System -- Chapter 9: Ultrasound of the Endocrine System -- Chapter 10: Ultrasound of the Reproductive System -- Chapter 11: Ultrasound of the Nervous System -- Chapter 12: Introducing Ultrasound into a Physiology Course from A to Z.
    Abstract: This book will be of interest to anyone who wants to use ultrasound to understand human physiology both in the clinical setting and the classroom. Tremendous advances in ultrasound technology have resulted in portable ultrasound systems that are easy to use, produce excellent images, and are affordable with quality hand-held and laptop-sized systems costing between $2K and $20K. These systems are now being used at the patient bedside or point of care by almost all medical and surgical specialities from primary care to orthopaedic surgery. These portable systems, especially the hand-held devices, are now being called the stethoscopes of the 21st century and will likely be used by many that are presently using stethoscopes including physicians, nurses, physician assistants, medics and other health professionals. Ultrasound began to be used in medical student education in the 1990s and is steadily becoming a common teaching tool for courses like anatomy and physiology. It is a visual, highly interactive learning tool that bridges the basic and clinical sciences and allows the learner to observe physiology principles in a living model. Ultrasound is also being used to teach other health professions students as well as undergraduate college students and high school students. Despite this interest there are no books available that provide an introduction to ultrasound and how it can be used to enhance the teaching of physiology. This e-book will do just that as well as offer “How to Scan” videos with example laboratory exercises to further engage learners.
    Type of Medium: Online Resource
    Pages: X, 323 p. 305 illus., 275 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9781071618639
    Series Statement: Physiology in Health and Disease,
    DDC: 612
    Language: English
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  • 126
    Keywords: Stress (Physiology). ; Plants. ; Molecular biology. ; Agriculture. ; Biotechnology. ; Plant Stress Responses. ; Molecular Biology. ; Agriculture. ; Biotechnology. ; Plant Signalling.
    Description / Table of Contents: 1. Targeted genome editing techniques in plant defense regulation -- 2. Synthetic promoters in regulating disease gene expression -- 3. Transcription factors associated with defense response against fungal biotrophs -- 4. Transcription factors associated with defense response against fungal necrotrophs -- 5. Transcription factors associated with defense response against viruses -- 6. Role of microbial bio-agents as elicitors in plant defense regulation -- 7. Transcriptional Factors Response under Biotic Stress in Wheat -- 8. Potential Transcription Factors for Biotic Stress Tolerance in Sugarcane -- 9. Role of transcription factors in response to biotic stresses in Maize -- 10. Role of transcription factors in response to biotic stresses in Pearl millet -- 11. Role of transcription factors in response to biotic stresses in Tomato -- 12. Role of transcription factors in response to biotic stresses in potato (Solanum tuberosum L.).
    Abstract: With the erratic changes in climate, crop plants are facing many forms of biotic stresses. When plants are under stress, among several gene families, regulatory genes play a vital role in signal transduction in modulating the expression of genes underpinning several defense pathways and targeting regulatory proteins (viz, transcription factors (TFs)) can be the alternative. Transcription factors directly regulate the downstream R genes and are excellent candidates for disease resistance breeding. Till date, numerous transcription factors have been identified and characterized structurally and functionally. Of them, TF families such as WRKY, NAC, Whirly, Apetala2 (AP2), ethylene responsive elements (ERF) etc. are found to be associated with transcriptional reprogramming of plant defense response. These TFs are responsive to the pathogen’s PAMPs/DAMPs - host’s PRR protein interactions and specifically binds to the cis-elements of defense genes and regulate their expression. With this background, realizing the importance of TFs in resistance breeding, this book discusses the recent research and developments in this field for various crops.
    Type of Medium: Online Resource
    Pages: VIII, 247 p. 26 illus., 25 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031129902
    DDC: 581.788
    Language: English
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  • 127
    Keywords: Neurosciences. ; Life sciences. ; Biology Technique. ; Evolution (Biology). ; Neuroscience. ; Life Sciences. ; Experimental Organisms. ; Evolutionary Biology.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2.General Rules of Brain Morphogenesis in Vertebrates: An Hourglass Model -- Chapter 3.Neural Tube Formation -- Chapter 4.Subdivisions of Neural tube along the Dorsoventral Axis -- Chapter 5. Subdivisions of Neural Tube along the Rostrocaudal Axis: Neuromeric Models -- Chapter 6.Left-right Patterning of Neural Tube -- Chapter 7. Ventriculo-pial Patterning of Neural Tube -- Chapter 8.Development of Neural Circuits in Neural Tube -- Chapter 9.From Neural Tube to Larval Brain: Blood Vessels and Proliferative Zones -- Chapter 10. Development of Telencephalon -- Chapter 11. Development of Diencephalon, Optic Tectum, and Cerebellum -- Chapter 12. Nervous System in Medaka Larvae -- Chapter 13.From Larval Brain to Adult Brain and Summary of Telencephalic Ontogenesis -- Chapter 14. Adult Brain and General Brain Functions -- Chapter 15. Functional Neuroanatomy of Teleost Brains.
    Abstract: This book describes the developmental process of the brain of the medaka fish. It aims to understand the brain structure of vertebrates, including humans, by taking the brain of the medaka fish as an example and showing its actual developmental process. From developmental and evolutionary viewpoints, the understanding of the brain proceeds from simple to complex structures. Fish retain the basic form of vertebrates, and their brain morphology is relatively simple. Therefore, the fish brain is useful in understanding the brain structure. This book is unique for describing the entire process of the brain development in a specific fish. In addition, the book introduces the readers to a new concept of “Hourglass of Brain Morphogenesis”, concerning the general rule of brain morphogenesis in vertebrates. The authors propose that the brain morphology is highly conserved at the middle developmental stage but diverges more extensively at earlier and later stages. The new concept challenges the accepted theory that has been widely shared for about 200 years since K. von Baer (1828, 1837) and K. von Kupffer (1906) who proposed that three primary brain vesicles at earlier developmental stages develop into five secondary brain vesicles at later developmental stages in all vertebrates. The book provides a basic understanding of the vertebrate brain and is useful for all readers who wish to understand the complex structure of the brain. .
    Type of Medium: Online Resource
    Pages: XIV, 256 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811943249
    DDC: 612.8
    Language: English
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  • 128
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Epigenetics. ; Developmental biology. ; Evolutionary developmental biology. ; Molecular Evolution. ; Zoology. ; Evolutionary genetics. ; Epigenetics. ; Developmental Biology and Stem Cells. ; Evolutionary Developmental Biology. ; Molecular Evolution. ; Zoology. ; Evolutionary Genetics.
    Description / Table of Contents: Chapter 1. An Introduction to Epigenetics, Development, Ecology and Evolution. Chapter 2. Epigenetic Regulation: The Cross-Talk among Development, Adaptive Strategies, and Microevolutionary Change -- Chapter 3. Epigenetics and Phenotypic Plasticity in Animals -- Chapter 4. Role of Environmentally Induced Epigenetic Transgenerational Inheritance in Evolutionary Biology -- Chapter 5. Transgenerational Epigenetic Programming -- Chapter 6. Epigenetics, Evolution and Development of Birds -- Chapter 7. Epigenetics and the Extreme Stress Response -- Chapter 8. Epigenetic Adaptation to Local Ecologies as a First Step toward Gene: Culture Co-evolution.
    Abstract: Epigenetic modifications comprise heritable gene expression changes that occur without alteration of the DNA sequence and 'co-act' with genetic factors to shape development processes and evolutionary trajectories. Multicellular organisms receive different types of environmental stimuli/stresses that trigger epigenetic modifications during development. These environmentally driven mechanisms represent an underlying cause of phenotypic diversity, especially in metazoans. This book aims to present some of the latest epigenetic insights into the development of metazoans (including humans) as an intersection between their ecology and evolution.
    Type of Medium: Online Resource
    Pages: XII, 232 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031137716
    DDC: 572.865
    Language: English
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  • 129
    Keywords: Zoology. ; Animal culture. ; Invertebrates. ; Zoology. ; Animal Science. ; Invertebrate Zoology.
    Description / Table of Contents: Chapter 1. Nature And Sources of Data For Inland Fisheries Management -- Chapter 2. Concept of Sampling Methodologies and Their Applications -- Chapter 3. Descriptive Statistics for Inland Fisheries Data -- Chapter 4. Basic Concept of Hypothesis Testing and Parametric Test -- Chapter 5. Chi–Square Test of Significance -- Chapter 6. Use of Non–Parametric Test in Fisheries Data -- Chapter 7. Analysis of Variance (Anova) and Design of Experiments -- Chapter 8. Concept of Simple Correlation and Regression -- Chapter 9. Analysis and Interpretation of Weight–Length Data of Fish -- Chapter 10. Some Multivariate Analysis Techniques for Fisheries Data -- Chapter 11. Introduction to Electronic Spreadsheet and Microsoft Excel -- Chapter 12. Introduction to R Software -- Chapter 13. Introduction To Graphics in R.
    Abstract: This authored book is primarily for the readers who are in search of how to use basic concepts of statistics in the field of fishery science. It has been written for the new comers coming in the fishery sector including university students, teachers and research scholars. It enriches the reader’s knowledge of data analysis step by step starting from data collection to its analysis and interpretation along with practical application with real example. It supports readers for enhancing theoretical and practical concept of application of fundamental statistics in fishery domain. Reader may also learn how to analyses data using different statistical software. Each chapter starts with an introduction of the topic followed by statistical concept with example and ends with chapter based question for comprehension purpose. This book is of interest to teachers, researchers, scientists, capacity builders in fishery sciences. Also the book serves as additional reading material for undergraduate and graduate students of fisheries and aquatic sciences.
    Type of Medium: Online Resource
    Pages: XXVIII, 257 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811944116
    DDC: 590
    Language: English
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  • 130
    Keywords: Zoology. ; Veterinary medicine. ; Freshwater ecology. ; Marine ecology. ; Zoology. ; Veterinary Science. ; Freshwater and Marine Ecology.
    Description / Table of Contents: Chapter 1. Who are the marine mammals? -- Chapter 2. Marine mammal acoustics -- Chapter 3. Whaling, seal culling, and the effect of fisheries on marine mammals -- Chapter 4. Plastic debris and its impacts on marine mammals -- Chapter 5. Chemical pollution and diseases of marine mammals -- Chapter 6. How to become a marine mammal scientist.
    Abstract: This highly-readable Open Access textbook provides basic background information about marine mammals and anthropogenic impacts on them. The book includes inspiring exercises for education school programs in natural sciences. The book also provides advice on career paths using case studies of marine scientists and veterinarians describing their journeys from student to profession. By sharing real-life career paths, readers find answers to questions such as “What needs to be considered when choosing a career in science?” and “What kind of tasks do scientists undertake on a daily basis?” Marine mammals are amongst some of the most celebrated creatures on Earth, with their high intelligence, social and communicating skills, and capacity for deep diving. Alongside general information about marine mammals, the book aims at generating awareness of the impact of litter and noise pollution on the marine environment using marine mammals as an example. Huge numbers of marine animals, including marine mammals, die every year from entanglement in fishing gear, by ingestion of litter or because of chemical pollution. In the last decade many technological and scientific tools have been developed to aid research, for instance miniaturised sound recorders which can be attached to cetaceans and seals and record noise levels around them, their vocal production as well as their diving behaviour. This Open Access textbook can be used by undergraduate students interested in the fundamentals of marine mammal biology and medicine, and in pursuing the profession of a marine scientist. .
    Type of Medium: Online Resource
    Pages: X, 95 p. 32 illus., 30 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031068362
    DDC: 590
    Language: English
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  • 131
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Plant diseases. ; Molecular biology. ; Genetics. ; Plant Pathology. ; Molecular Biology. ; Genetics and Genomics.
    Description / Table of Contents: 1. Genomics of crucifers’ host-pathosystem - Prologue -- 2. Crucifers’ pathogens genome -- 3. Genomics of host- pathogen interaction -- 4. Molecular detection and Identification of pathogens, pathotypes and genes -- 5. Pathogenomics of pathogenic variability -- 6. Bio-metabolomics of crucifer’s host-pathosystem -- 7. Genomics of crucifer’s host-pathosystem at a glance -- 8. Protocols to study host-pathosystem -- 9. Future research priorities of crucifers’ host pathosystem -- 10. Subject index.
    Abstract: The book deals with latest research achievements of Brassica scientists using omics approaches in understanding host-pathogen interaction, molecular detection, identification, and functional characterization of effectors/genes including pathogenomics and biometabolomics. Genomics of host-pathogen interaction is a source of information for the teachers, students, researchers, and policy makers to foster success in enhancing the Brassica production and productivity through the development of improved disease-resistant varieties with the use of omics technologies. It is a base and sound plate form for managing biological stresses of Brassica at global level. The book covers up-to-date information on genomics of host-pathogen interaction, pathogenomics of crucifers’ pathogen, and biometabolomics of host pathosystem supplemented with ample photographs, illustrations, and figures which make it stimulating, effective, and easy to comprehend for readers, researchers, biology students, teachers, and policy makers.
    Type of Medium: Online Resource
    Pages: XXIII, 930 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811938122
    DDC: 571.92
    Language: English
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  • 132
    Keywords: Ecology Methodology. ; Biotic communities. ; Plant ecology. ; Ecological Modelling. ; Ecosystems. ; Plant Ecology.
    Description / Table of Contents: 1. Modelling tools and plausible scenarios in science-policy to improve evidence based decision making for human-well-being -- 2. Basic Introduction to Species Distribution Modelling -- 3. Machine Learning based predictive modelling approaches for better understanding evolutionary history, distribution and niche occupancy: Experience from Western Ghats -- 4. Mapping the impact of climate change on eco-sensitive hotspots using species distribution modelling (SDMs) – Gaps, Challenges and Future Perspectives -- 5. Approaches for modelling the climate change impacts on ecosystems -- 6. Developing a Bayesian Model of Climate-Induced Lake Overturn in Talisay, Taal Lake -- 7. Global sensitivity and uncertainty analysis of MaxEnt model: Implications in species habitat projections -- 8. Tree species diversity and richness patterns reveal high priority areas for conservation in Eswatini -- 9. Improving the conservation status of a threatened tree (Acer sikkimensis Miq. syn. Acer hookeri Miq.) through standardization of seed germination protocol and using ecological niche modeling -- 10. Ecological Niche Modeling of the endemic Himalayan near-threatened treeline conifer Abies spectabilis (D.Don) Mirb. in the Indian Central Himalaya -- 11. Modeling the distribution of a medicinal plant Oroxylum indicum (L.) Kurz for its conservation in Arunachal Pradesh -- 12. Habitat Suitability and Niche Modeling for Conservation and Restoration of Aconitum heterophyllum Wall. in Temperate Himalayan Forest Ecosystem -- 13. Application of species distribution modeling for conservation and restoration of forest ecosystems -- 14. Habitat suitability analysis of Asiatic Elephants (Elephas maximus) in the Tropical Moist Deciduous Forest of Assam using Analytic Hierarchy Process (AHP) -- 15. Factors Affecting the Habitat Suitability of Eastern Swamp Deer (Rucervus duvaucelii ranjitsinhi Groves, 1982) in Manas National Park and Implication for Terai Grassland Restoration -- 16. Evaluating Potential Habitats of Chital, Sloth Bear and Jungle Cat in Selected Areas of Central Indian Landscape -- 17. Habitat suitability modeling of Tor tor (Hamilton, 1822) in the Indian drainage systems using MaxEnt -- 18. Modelling the influence of Marine Fishery Advisories on the reduction of Carbon Dioxide emissions for Odisha under varying Climate Change Scenarios using CMIP models – an evidence-based approach for policymaking -- 19. Impacts of pollution on tropical montane and temperate forests of South Asia: Preliminary studies by post graduate students in India and Sri Lanka -- 20. Selection of strategic sampling sites for river quality assessments near mined areas as a policy handle for low-impact development and biodiversity conservation – a case study of River Godavari -- 21. Ecological niche modeling predicts the potential area for cultivation of Melia dubia Cav. (Meliaceae): a promising tree species for agroforestry in India -- 22. Proportions of change in the airborne particulate matter (PM10) concentrations across selected states in Peninsular India - a study of decadal, pre-pandemic trends for planning restoration -- 23. Decomposition of Sunflower Cuttings and its Impact on Soil Fertility of Rice Terraces (Payoh) in Banaue, Ifugao, Philippines -- 24. Forest ecosystem modeling for policy planning: A review -- 25. Ecological Carrying Capacity Modelling and Sustainability Assessment of the Seven Lakes of San Pablo City, Laguna, Philippines -- 26. Assessment of the contribution of Fresh Water Ecosystem Services to the Hydropower Sector in the Kura-Araz basin -- 27. Eutrophication modelling of Chilika Lagoon using an artificial neural network approach.
    Abstract: This edited book is focused on SDG 15. This volume covers aspects of species and ecosystem modeling in understanding the complexity of ecological systems, restoration, protected area management, and species conservation. The book follows a systematic and situation-sensitive approach to discuss ecosystem and species modeling tools, approaches, science, case studies, opportunities, and gaps for enhancing conservation efforts, ensuring ecosystem resilience, and addressing sustainability issues. The book emphasizes on science, innovations, case studies, and strategic relevance as main pillars of using ecosystem and species modeling tools and implementing the outcomes and results. In addition, clear conceptual frameworks, elaborated methodologies, and their applications are included to support policy planning and interventions to reduce and reverse human encroachment in human-dominated natural ecosystems, their degradation, and loss of important species and ecosystem services. Essential information with a special focus on advances and opportunities in advancing the implementation of results and outputs of the modeling tools, challenges and constraints for addressing loss of ecosystem services, designing and implementing sustainable landscape restoration, environmental risk assessment, and finally understanding policy implications and concerns for mainstreaming modeling results in conservation planning and decision-making is included in the book. Further topics include ultimate translational value of modeling tools and efforts across transitional ecosystems and species habitat to provide better evidence to influence the nature-based solutions (NbS) and ecosystem health assessment using Red List of Ecosystems (RLE). The emerging roles of integrative socio-ecological as well as techno-cultural factors in promoting the relevance of ecosystem and species modeling is one of the key features of this book. This edited volume is of interest and useful to researchers, students, scholars, policy makers, forest managers, consultants, and policy makers in the fields of protected area management, forest department, conservation, modeling, climate change, and sustainability science, and also authors engaged in IPBES, IPCC, and several other assessments.
    Type of Medium: Online Resource
    Pages: XXXV, 570 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819901319
    DDC: 577
    Language: English
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  • 133
    Keywords: Neurosciences. ; Pain medicine. ; Neurology . ; Anesthesiology. ; Neuroscience. ; Pain Medicine. ; Neurology. ; Anesthesiology.
    Description / Table of Contents: Introduction to Acute, Chronic, and Episodic Pain -- Inflammation and Pain -- Animal Models of Pain and Anti-inflammatory Treatments -- Inflammatory Mediators, Nociceptors, and Their Interactions in Pain -- Immune and Glial Cells in Pain and Their Interactions with Nociceptive Neurons -- Sex Differences in Neuroimmune Interactions and Pain -- Neuroimmune Interactions in Itch -- Toll-like Receptors in Pain and Itch -- Immunotherapy and Pain -- Cell Therapy and Regenerative Pain Medicine - Preclinical Studies -- Cell-based Therapies in Pain Management -- Platelet-Rich Plasma and Autologous Conditioned Serum: Non-Cellular Biologic Therapies for Neuroimmune Modulation and the Treatment of Arthritis Pain -- Exercise and Diet in the Control of Inflammation and Pain -- Mechanism-Based Pain Therapies -- Neuromodulation in Pain Management -- What Patients Need to Know about Pain Therapy?.
    Abstract: As lifespans increase, more people around the world find themselves victims of chronic pain. In spite of this, treatment options continue to be severely limited. Anti-inflammatory drugs can only do so much, while painkillers like opioids have led to crippling addictions and fatal overdoses. The subject of the book is the role of immune cells, including glial cells, and neuroimmune interactions in chronic pain. The book begins by examining the preclinical and clinical evidence supporting the involvement of non-neuronal cells in chronic pain. It discusses the interactions between non-neuronal cells and neurons in the regulation of chronic pain. It then presents the implications of these findings, including promising and emerging treatments such as specialized pro-resolving mediators (SPMs, such as resolvins and protectins), immune cell therapy, and complementary and alternative medicine, as well as neuromodulation and regenerative medicine, which may prove to be the turning point for hundreds of millions of patients world-wide who struggle to escape from the shadow of chronic pain. The book presents ground-breaking research that will alter current perspectives on chronic pain.
    Type of Medium: Online Resource
    Pages: X, 364 p. 45 illus., 41 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031292316
    DDC: 612.8
    Language: English
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  • 134
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Stem cells. ; Hematology. ; Regenerative medicine. ; Biotechnology. ; Stem Cell Biology. ; Hematology. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: Hematopoietic Stem Cells -- Mesenchymal Stem Cells -- Cord Blood Stem Cells -- Neural Stem Cells and Their Niche -- Skeletal Muscle Stem Cells -- Heart Muscle Tissue Engineering -- Induced Pluripotent Stem Cells -- Epigenetics of Somatic Cell Reprogramming -- Human Pluripotent Stem Cells and Neural Regeneration -- Dopaminergic Neuron-Related Stem Cells -- Liver Disease Modelling -- Organoids in Developmental Biology Research and Application -- Extracellular Vesicles -- Ethics in Stem Cell Applications.
    Abstract: This textbook describes the biology of different stem cell types and outlines the current level of knowledge in the field. It clearly explains the basics of hematopoietic, mesenchymal cord blood, neural and muscle stem cells and also covers induced pluripotent stem cells and their applications. Further, it includes chapters on organoids, stem-cell based disease modelling, extracellular vesicles and one chapter on ethical aspects of human stem cell research, which promotes critical thinking and responsible handling of the material. Based on lectures of the international master program Molecular and Developmental Stem Cell Biology taught at Ruhr-University Bochum and participation of collaborating professors from Tongji University Shanghai, the book is a valuable source for students, postdocs and researchers, who would like to have introductory chapters on stem cell biology. It also offers essential insights for physicians and dentists wishing to expand their knowledge. This textbook is a valuable complement to Concepts and Applications of Stem Cell Biology, also published in the Learning Materials in Biosciences textbook series.
    Type of Medium: Online Resource
    Pages: XIV, 242 p. 37 illus., 35 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030339234
    Series Statement: Learning Materials in Biosciences,
    DDC: 660.6
    Language: English
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  • 135
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Agriculture. ; Plant biotechnology. ; Plants Development. ; Agriculture. ; Plant Biotechnology. ; Plant Development.
    Description / Table of Contents: Chapter 1. Plant Breeding & Indian Agriculture -- Chapter 2. Plant Breeding & Seed Industry in India -- Chapter 3. Role of Education to Strengthen Plant breeding Capacity -- Chapter 4. Strategies to Strengthen Plant Breeding Status in India.
    Abstract: Plant breeding has the potential to improve quality of life for millions of people, and to harmoniously link agriculture, societies and ecosystems. Global efforts have been made to improve awareness and create a better and brighter future for plant breeding worldwide. Though substantial international research funding is available, and tremendous efforts have been made to achieve food security and sustainability in agriculture, their success can only be ensured when they are complemented by counterparts at the national level. India is ideally poised to reap the benefits of plant breeding by integrating various parameters like adaptation, uncertainty, vulnerability and resilience into agriculture research strategies. Priorities include making agriculture more appealing to young talents, formulating farmer-friendly policies, combining advanced technologies with conventional plant breeding practices, and building the competencies needed to address emerging challenges in agriculture. This book provides an essential overview of modern plant breeding, and demonstrates how education, entrepreneurship training and professional approaches can help transform the image of agriculture from a poor and unattractive domain into a lucrative and business-oriented one. In addition, it presents strategies to help achieve sustainable, accessible and affordable outcomes with breeding programs. The book’s primary goal is to encourage policymakers, academics, private institutions and non-profit organizations to combine their efforts in order to achieve a major transition in plant breeding activities in Asia. Accordingly, it highlights the importance of partnerships and collaborations for making breeding programs more comprehensive and meaningful.
    Type of Medium: Online Resource
    Pages: XIII, 127 p. 24 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811519062
    DDC: 630
    Language: English
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  • 136
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Neurosciences. ; Neurology . ; Evolution (Biology). ; Psychobiology. ; Human behavior. ; Neuroscience. ; Neurology. ; Evolutionary Biology. ; Behavioral Neuroscience.
    Description / Table of Contents: Sleep: Basic and Historical Aspects -- Sleep: Findings in Invertebrates and Lower Vertebrates -- Sleep: Evolutionary and Adaptive Changes in Birds and Mammals -- Sleep Loss: What Does it do to our Brain and Body -- Sleep: Neural Optimization as An Ultimate Function for Memory Consolidation -- Sleep: Disorders and Clinical Implications.
    Abstract: This book discusses the evolution of sleep and its possible function in the higher invertebrates and vertebrates, including humans. It describes the current concept of sleep and its functions, based on research on the mammalian system. To date, electrophysiological recordings of the brain waves, muscle activity, and eye movements are the only tools available for characterizing the sleep architecture in the majority of animals. In mammals and birds, only two distinct types of sleep are found – non-rapid eye movement (NREM) and rapid eye movement (REM) sleep. Since the discovery of REM sleep, studies have been performed to understand the purpose of the two distinct sleep states in higher vertebrates (birds and mammals), and how REM sleep was evolved. The book summarizes the role of both REM and NREM sleep in the proper functioning of the brain and body. It covers various aspects of the role of sleep in important physiological processes, including memory consolidation, induction of synaptic plasticity, energy restoration, enhancing immune response, and maturation of neuronal circuitries during early life. Lastly, the book reviews the effects of chronic/acute sleep deprivation on memory consolidation, obesity, and the immune system in animal models and humans.
    Type of Medium: Online Resource
    Pages: XIV, 118 p. 30 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811571756
    DDC: 612.8
    Language: English
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  • 137
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Pharmacology. ; Pharmaceutical chemistry. ; Pharmacology. ; Pharmaceutics.
    Description / Table of Contents: 1 Principles of pharmaceutical analysis in drug stability and chemical kinetics -- 2 Guidelines for drug stability and stability testing -- 3 Chemical kinetics and its applications in drug stability -- 4 Methods and protocols for drug stability studies -- 5 Physical basis of degradation of pharmaceutical products -- 6 Role of microbiological degradation on drug stability -- 7 Role of decomposition on drug stability -- 8 Role of catalysis in drug stability -- 9 Analytical techniques for the assessment of drug stability -- 10 Stability of pharmaceutical products -- 11 Role of kinetic models in drug stability -- 12 Stability studies of vaccines -- 13 Stability studies of proteinous compounds -- 14 Stability studies of extemporaneous pharmaceutical products -- 15 Stability studies of parenteral products -- 16 Stability studies of solid dosage forms.
    Abstract: This book comprehensively reviews drug stability and chemical kinetics: how external factors can influence the stability of drugs, and the reaction rates that trigger these effects. Explaining the important theoretical concepts of drug stability and chemical kinetics, and providing numerous examples in the form of illustrations, tables and calculations, the book helps readers gain a better understanding of the rates of reactions, order of reactions, types of degradation and how to prevent it, as well as types of stability studies. It also offers insights into the importance of the rate at which the drug is degraded and/or decomposed under various external and internal conditions, including temperature, pH, humidity and light. This book is intended for researchers, PhD students and scientists working in the field of pharmacy, pharmacology, pharmaceutical chemistry, medicinal chemistry and biopharmaceutics. .
    Type of Medium: Online Resource
    Pages: XIV, 284 p. 22 illus., 13 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811564260
    DDC: 615
    Language: English
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  • 138
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Immunology. ; Medical sciences. ; Cytology. ; Biochemistry. ; Nutrition   . ; Immunology. ; Health Sciences. ; Cell Biology. ; Biochemistry. ; Nutrition.
    Description / Table of Contents: Preface -- Amino acids in intestinal physiology and health -- Amino acid metabolism in the liver: nutritional and physiological significance -- Amino acids in circulatory function and health -- Epithelial dysfunction in lung diseases: effects of amino acids and potential mechanisms -- Amino acid metabolism in the kidneys: nutritional and physiological significance -- Amino acids in health and endocrine function -- Amino Acids in Reproductive Nutrition and Health -- Impacts of amino acids on the intestinal defensive system -- Maternal nutrient restriction and skeletal muscle development: Consequences for postnatal health -- Metabolism of amino acids in the brain and their roles in regulating food intake -- Metabolism and functions of amino acids in the skin -- Metabolism and functions of amino acids in sense organs. .
    Abstract: This edited volume comprehensively highlights recent advances in the metabolism, nutrition, physiology, and pathobiology of amino acids in all the systems of humans and other animals (including livestock, poultry, companion animals, and fish). It enables readers to understand the crucial roles of amino acids and their metabolites in the health and diseases of the circulatory, digestive, endocrine, immune, muscular, nervous, reproductive, respiratory, skeletal, and urinary systems, as well as the sense organs (eyes, ears, nose, skin, and tongue). Readers will learn that amino acids are not only the building blocks of protein, but are also signalling molecules, as well as regulators of gene expression, metabolic processes and developmental changes in the body. This knowledge will guide nutritional practices to improve the growth, development and health of humans and other animals, as well as prevent and treat chronic (e.g., obesity, diabetes, and cardiovascular disorders) and infectious (e.g., bacterial, fungal, parasite, and viral) diseases. Editor of this volume is an internationally recognized expert in nutritional biochemistry. He has over 38 years of experience with research and teaching at world-class universities in the area of amino acid biochemistry, nutrition, and physiology. He has published more than 625 papers in peer-reviewed journals, 62 chapters in books, and authored two text/reference books, with an H-index of 117 and more than 55,000 citations in Google Scholar. This publication is a useful reference for professionals as well as undergraduate and graduate students in animal science, biochemistry, biomedical engineering, biology, human medicine, food science, kinesiology, nursing, nutrition, pharmacology, physiology, toxicology, veterinary medicine, and other related disciplines. In addition, all chapters provide general and specific references to amino acids in systems health for researchers and practitioners in biomedicine, animal and plant agriculture, and aquaculture, and for government policy makers.
    Type of Medium: Online Resource
    Pages: VI, 220 p. 36 illus., 10 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030453282
    Series Statement: Advances in Experimental Medicine and Biology, 1265
    DDC: 571.96
    Language: English
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  • 139
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biotechnology. ; Engineering design. ; Heart Surgery. ; Control engineering. ; Robotics. ; Automation. ; Biotechnology. ; Engineering Design. ; Cardiac Surgery. ; Control, Robotics, Automation.
    Description / Table of Contents: Chapter 1. Evolution of Artificial Heart Technology -- Chapter 2. Mechanisms of Heart Failure -- Chapter 3. Basis of Artificial Heart Technologies -- Chapter 4. Artificial Heart: Rotary Pump -- Chapter 5. Artificial Heart: Volume-Displacement Pump -- Chapter 6. Total Artificial Heart -- Chapter 7. Evaluation of Artificial Hearts -- Chapter 8. Selection of Artificial Heart Devices -- Chapter 9. Therapy Management of VADs -- Chapter 10. Challenges of Artificial Heart Devices -- Chapter 11. A Primary Study for Biocompatible Ventricular Assist Devices.
    Abstract: This book provides a comprehensive introduction to artificial hearts, summarizing the latest advances in basic technologies, design, evaluation, and management. Featuring 11 chapters, it discusses the origins of the artificial heart, the mechanisms of heart failure, and the principles of artificial heart technologies. Further, it offers an overview of rotary pumps and volume-displacement pumps, and addresses total artificial hearts. Lastly, the book covers evaluation, selection, therapy management, challenges, and the latest innovations. Given its scope, it is a valuable resource for researchers and technicians in the area of biomedical engineering, as well as surgeons.
    Type of Medium: Online Resource
    Pages: XV, 212 p. 37 illus., 27 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811543784
    DDC: 660.6
    Language: English
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  • 140
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Cytology. ; Internal medicine. ; Biochemistry. ; Physiology. ; Biomedical Research. ; Cell Biology. ; Internal Medicine. ; Biochemistry. ; Physiology.
    Description / Table of Contents: Preface -- Part 1 Basics on coenzyme Q -- Introduction. The current coenzyme Q science and knowledge -- Molecular structure, biosynthesis, and distribution of coenzyme Q -- Coenzyme Q function in mitochondria -- Extramitochondrial coenzyme Q10 in aging -- Regulation of the synthesis of Coenzyme Q10 -- Part 2 Coenzyme Q in aging studies -- Coenzyme Q and aging in C. elegans -- Coenzyme Q and aging in the fruit fly Drosophila melanogaster -- The aging process and coenzyme Q: clk-1 mouse models -- Reduced coenzyme Q10 decelerates senescence and age-related hearing loss in senescence-accelerated mice by activating mitochondrial functions -- Part 3 Age-related diseases and coenzyme Q -- Coenzyme Q, mtDNA and mitochondrial dysfunction during aging -- Coenzyme Q10 and metabolic syndrome -- Coenzyme Q and age-related neurodegenerative disorders: Parkinson and Alzheimer diseases -- Immunosenescence and CoQ10 -- Coenzyme Q10 in fertility and reproduction -- Part 4 Prolongevity effectors and Coenzyme Q -- Calorie restriction, longevity and coenzyme Q -- Age dependent changes of coenzyme Q levels and its induction in experimental systems -- Effects of coenzyme Q10 supplementation on elderly people -- Index.
    Abstract: This book offers a comprehensive exploration of research on the essential relationship of the coenzyme Q10 and the process of aging in living organisms. CoQ10 is an important factor in two main aspects of cell physiology: bioenergetics and antioxidant protection. While primary deficiency of CoQ10 is associated with severe and lethal disease, secondary deficiency can be associated with the progression of mitochondrial dysfunction linked to the lessening of biological activities during aging. The book is organized in four sections. The first offers an overview of the function of CoQ10, highlighting the two main functions of CoQ10 in cells: its essential role as electron transport chain member in mitochondria, and the protection of cell membranes against oxidation as one of the main endogenous-synthesized antioxidants. The second section covers research on Coenzyme 10. Topics include studies involving invertebrate models, mammal studies and the influence of CoQ on longevity. Also covered is research involving the role of CoQ in senescence-accelerated mice. Section three examines the effects of reduced CoQ in human aging, as evident in mitochondrial dysfunction, metabolic syndrome, neurodegenerative disorders, immunosenescence and fertility and reproduction. The final section, Prolongevity effectors and Coenzyme Q, explores research into slowing or stopping the aging process. Coverage includes strategies including calorie restriction, and modulation of CoQ10 levels by induction of synthesis or by supplementation. Coenzyme Q in Aging benefits a broad readership of researchers, clinicians, educators and students interested in the biochemical and physiological effects of coenzyme Q and the importance of this molecule in aging process.
    Type of Medium: Online Resource
    Pages: XII, 369 p. 50 illus., 17 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030456429
    DDC: 610.72
    Language: English
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  • 141
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    Singapore :Springer Nature Singapore :
    Keywords: Biochemistry. ; Food science. ; Biochemistry. ; Food Science.
    Description / Table of Contents: Chapter 1. History of Starch Research -- Chapter 2. Botanical Sources of Starch -- Chapter 3. Fine Structure of Amylose and Amylopectin -- Chapter 4. Multi-scale Structures of Starch Granules -- Chapter 5. Amylose-Lipid Complex -- Chapter 6. Phase Transitions of Starch and Molecular Mechanisms -- Chapter 7. Rheological, Pasting and Textural Properties of Starch -- Chapter 8. Starch Modification and Application -- Chapter 9. In vitro Starch Digestion: Mechanisms and Kinetic Models.
    Abstract: The book summarizes the latest research on starch structures and how these structures occur during food processing and storage. Discussing the origins, multi-scale granule structures and functional properties of starch as well as starch digestion, it focuses on the relationship between starch structure and functionality, the phase transition mechanism, the molecular disassembly and self-assembly of starch during food processing and storage and their effects on starch digestion. As such, the book provides a comprehensive overview of starch structure and functionality for researchers and postgraduate students in the field of food chemistry, carbohydrate polymers, polymer chemistry, food ingredients and food processing as well as human nutrition and health.
    Type of Medium: Online Resource
    Pages: V, 179 p. 45 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811506222
    DDC: 572
    Language: English
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  • 142
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    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Human physiology. ; Urology. ; Biophysics. ; Human Physiology. ; Urology. ; Bioanalysis and Bioimaging.
    Description / Table of Contents: Introduction of human sperm ultrastructural morphology -- Ultrastructural morphology of human sperm head -- Ultrastructural morphology of human sperm neck -- Ultrastructural morphology of human sperm middle piece -- Ultrastructural morphology of human sperm principal piece -- Ultrastructural morphology of human sperm terminal piece -- Ultrastructural morphological measurement of human sperm -- Artefacts of human sperm ultrastructural morphology -- Phenomena related to inadequate preparation of human sperm.
    Abstract: This atlas provides ultrastructural morphological images of human spermatozoa. Sperm morphology plays an essential role in sperm-oocyte interactions and early embryonic development, and human sperm ultrastructural morphology offers a valuable reference tool for assessing certain etiologies of male infertility and reproductive failure. However, the ultrastructural morphology of human sperm has not been systematically evaluated or thoroughly described in the literature. Using 470 original and unpublished images, the book shows various ultrastructural morphological phenotypes; defects of the sperm head, neck, middle piece, principal piece, and terminal piece; as well as artifacts of sperm ultrastructural morphology and phenomena related to inadequate preparation, demonstrating several sperm phenotypes and surface structural appearances for the first time. As such, it helps researchers and practitioners in andrology, reproductive medicine, and reproductive pathology gain a better understanding of human sperm ultrastructural morphology.
    Type of Medium: Online Resource
    Pages: XIII, 276 p. 370 illus., 2 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811553257
    DDC: 612
    Language: English
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  • 143
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    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Toxicology. ; Pharmacology. ; Toxicology. ; Pharmacology.
    Description / Table of Contents: 1. Exposure Durations of Environmental Stresses or Toxicants -- 2. Exposure Stages of Environmental Stresses or Toxicants -- 3. Complex Exposures to Environmental Toxicants or Stresses -- 4. Transgenerational Toxicity of Environmental Toxicants or Stresses -- 5. Exposure Routes of Environmental Toxicants -- 6. Basic Endpoints for Toxicity Assessment of Environmental Toxicants or Stresses -- 7. Endpoints for Assessing the Toxicity on Primary Targeted Organs -- 8. Endpoints for Assessing the Toxicity on Secondary Targeted Organs -- 9. Endpoints for Assessing the Toxicity on Biochemical Processes -- 10. Endpoints for Assessing the Genotoxicity and the Genetic Toxicity -- 11. Role of Exposure Dose in Toxicity Induction of Environmental Toxicants or Stresses -- 12. Role of Environmental Factors in Toxicity Induction of Environmental Toxicants or Stresses -- 13. Effects of Environmental Sample Forms on Toxicity Induction -- 14. Roles of Physicochemical Properties of Toxicants in Toxicity Induction -- 15. Roles of Environmental Media and Chemical Transformations of Environmental Toxicants in Toxicity Induction -- 16. Bioavailability, Enrichment, and Translocation of Environmental Toxicants -- 17. Susceptibility to Toxicants or Stresses Induced by Genetic Mutations -- 18. Contributors to Amplify the Toxicity of Toxicants or Stresses -- 19. Exposure to Certain Environmental Stresses -- 20. High-Throughput Toxicity Assessment -- 21. Toxicity Assessment under the Pathological Conditions.
    Abstract: This book focuses on exposure toxicology in C. elegans. The nematode Caenorhabditis elegans is sensitive to various environmental toxicants and stresses, and has proven to be an important animal model in both molecular and target-organ toxicology. As a result, over the past 30 years, there has been extensive research on the exposure to environmental toxicants or stresses in nematodes. Based on the available data, the book offers an introduction to the exposure system established in nematodes, discussing various aspects of endpoints that can potentially be used to assess the toxicity of environmental toxicants or stresses. Also exploring various factors affecting toxicity induction, and exposure to environmental toxicants and stresses, it allows readers to gain a systematic understanding of exposure toxicology in C. elegans. .
    Type of Medium: Online Resource
    Pages: XIX, 682 p. 447 illus., 303 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811561290
    DDC: 615.90072
    Language: English
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  • 144
    Keywords: Fungi. ; Mycology. ; Microbiology. ; Agriculture. ; Plants Evolution. ; Plant biotechnology. ; Plants Development. ; Fungi. ; Agriculture. ; Plant Evolution. ; Plant Biotechnology. ; Plant Development.
    Description / Table of Contents: Preface -- Introduction to Agriculturally Important Fungi for Crop Protection -- Role of Fungi in Adaptation of Agriculture Crops to Abiotic Stresses -- Arbuscualr Mycorrhizae Associations and Role in Mitigation of Drought Stress in Plants -- Fungal Mediated Alleviation of Cold Stress for Growth and Yield of Cereal Crops -- Soil Salinity and their Alleviation Using Plant Growth Promoting Fungi -- Phytohormones Producing Fungal Communities -- Fungal Secondary Metabolites and Bioactive Compounds for Plant Defence -- Fungal Endophytes -- Aspergillus Mycotoxins -- Trichoderma -- Piriformospora indica -- Bioresources for Control of Plant Parasitic Nematodes -- Global Scenario of Advance Fungal Research in Biocontrol and Crop Protection -- Index -- .
    Abstract: Microbes are ubiquitous in nature. Among microbes, fungal communities play an important role in agriculture, the environment, and medicine. Vast fungal diversity has been found in plant systems. The fungi associated with any plant system are in the form of epiphytic, endophytic, and rhizospheric fungi. These associated fungi play important roles in plant growth, crop yield, and soil health. The rhizospheric fungi present in rhizospheric zones have a sufficient amount of nutrients released by plant root systems in the form of root exudates for growth, development, and activities of microbes. Endophytic fungi enter in host plants mainly through wounds that naturally occur as a result of plant growth, or develop through root hairs and at epidermal conjunctions. The phyllospheric fungi may survive or proliferate on leaves, depending on the extent of influences of material in leaf diffuseness or exudates. The diverse group of fungal communities is a key component of soil-plant systems, where they are engaged in an intense network of interactions in the rhizospheric, endophytic, and phyllospheric areas, and they have emerged as an important and promising tool for sustainable agriculture. These fungal communities help to promote plant growth directly or indirectly by mechanisms for plant growth-promoting (PGP) attributes. These PGP fungi can be used as biofertilizers, bioinoculants, and biocontrol agents in place of chemical fertilizers and pesticides in an environmentally and eco-friendly manner. This book covers the current knowledge of plant-associated fungi and their potential biotechnological applications in agriculture and allied sectors. This book should be useful to scientists, researchers, and students of microbiology, biotechnology, agriculture, molecular biology, environmental biology, and related subjects.
    Type of Medium: Online Resource
    Pages: XVIII, 370 p. 40 illus., 20 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030484743
    Series Statement: Fungal Biology,
    DDC: 579.5
    Language: English
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  • 145
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Nervous system Surgery. ; Blood-vessels Surgery. ; Neurology . ; Neurosurgery. ; Vascular Surgery. ; Neurology.
    Description / Table of Contents: Brief History of Cavernous Malformations -- Definition and structure of cerebral cavernous malformations -- Molecular Biology of CCM -- Presentation -- Neuroimaging of Cerebral Cavernous Malformations -- Natural history of cavernous malformations -- Hemispherical Cavernomas in non-eloquent and eloquent areas -- Cavernoma-Related Epilepsy -- Surgery of deep-seated cavernous malformations -- Surgery of brainstem and cerebellar cavernous malformations -- Stereotactic Radiosurgery of Cavernous Malformations -- Cavernomas in children -- Cavernomas During Pregnancy -- Spinal cavernous malformations -- Intraorbital cavernous malformations.
    Abstract: This book presents a complete up-to date description of cavernoma disease together with its known biology, genetics and variable clinical presentation. It facilitates improved decision-making on surgical intervention by presenting different cases, highlighting the particular features of lesions such as anatomical location, eloquences of adjacent brain and type of presentation that are important when making decisions. In addition, the reader is brought up to speed with developments in the neuroimaging and active treatment techniques, especially surgical resection and radiosurgery. Finally, the natural history of the disease is taken into account and compared to the possible benefits of surgical treatment. Cavernomas of the CNS: Basic Science to Clinical Practice provides a comprehensive overview from the fundamentals of this condition, to special patient groups such as children and pregnant women. Therefore, it is an indispensable resource for neurovascular surgeons, neurosurgical residents and neurologists.
    Type of Medium: Online Resource
    Pages: VIII, 245 p. 124 illus., 38 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030494063
    DDC: 617.48
    Language: English
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  • 146
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Microbial ecology. ; Biotechnology. ; Environment. ; Industrial microbiology. ; Bacteria. ; Microbial Ecology. ; Biotechnology. ; Environmental Sciences. ; Industrial Microbiology. ; Bacteria.
    Description / Table of Contents: Part 1. Climate Change and Microbial Ecology -- Chapter 1. Microbes and Climate: A tangled relation -- Chapter 2. Carbon sequestration in aquatic system using Microbial pump -- Chapter 3. Climate change extenuation by green house gas quenching microflora -- Chapter 4. Role of Methanotrophs in Mitigating Global Warming -- Chapter 5. Paradigm Ecological Shift and Succession in Microbiomes – A Climatic Advent -- Chapter 6. Exploring the diversity of marine microbiome in response to changes in the environment -- Chapter 7. Polar microbes as climate resilient pathways for mitigation of climate change -- Part 2. Climate Change and pathogens -- Chapter 8. Climate change and population health -- Chapter 9. Impact of Climate Change on the Incidence and Transfer of Food and Water borne Diseases -- Chapter 10. Climate change: any dangers from antimicrobial resistant bacteria? -- Chapter 11. Phyllosphere Microbiome: Plant defense strategies -- Part 3. Climate Change and Agriculture -- Chapter Chapter 12. Understanding Methanogens, Methanotrophs and Methane Emission in Rice Ecosystem -- Chapter 13. Soil micro-flora and its role in diminution of global climate change -- Chapter 14. Role of microorganisms in plant adaptation towards climate change for sustainable agriculture -- Chapter 15. Novel approaches for genome editing to develop climate smart crops -- Part 4. Climate change and the Environmental Microbiology -- Chapter 16. Role of soil microbial flora in remediation of hydrocarbon stressed soils -- Chapter 17. Biosurfactant Producing Bacteria as Potent Scavengers of Petroleum Hydrocarbons -- Chapter 18. Potent biotechnological applications of psychrozymes -- Chapter 19. Role of Green Nanotechnology in Alleviating Climate Change.
    Abstract: This book covers the contemporary environmental issues faced by life on the planet and the role planetary microbiomes play in such issues. Providing insights on the net favorable and adverse effect of microbial processes, this volume covers both the spontaneous and anthropocentric events that impact climate change and life on the planet. The book describes the ecological significance of microbiomes associated with the kingdoms Plantae and Animalia with respect to climate change, natural and anthropogenic causes of climate change, microbial interactions in nature, planetary microbiomes and food security, climate change in relation to disease epidemiology and human health and engineering microorganisms to mitigate the consequences of climate change. The individual chapters in the intended book provide both theoretical and practical exposure to the current issues and future challenges of climate change in relation to the microbiomes. This collection should serve as ready reference to the researchers working in the area to reshape their future research in addressing the challenges of global climate change.
    Type of Medium: Online Resource
    Pages: XIII, 374 p. 41 illus., 33 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813345089
    DDC: 579.17
    Language: English
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  • 147
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Genetics. ; Molecular biology. ; Cancer Biology. ; Genetics and Genomics. ; Molecular Biology.
    Description / Table of Contents: 1. Introduction to cancer -- 2. Oncogenes, signal transduction and the hallmarks of cancer -- 3. Tumor suppressor genes and cell fate control -- 4. Multi-step tumorigenesis and genome instability -- 5. Cancer genomics -- 6. Cancer epigenomics -- 7. Aging and cancer -- 8. Tumor microenvironment -- 9. Metastasis and cachexia -- 10. Cancer immunity -- 11. Architecture of cancer therapies.
    Abstract: Cancer is a collection of diseases that can affect basically every organ of our body, all of which have in common uncontrolled cellular growth. The cells forming our body have the potential to grow in the context of wound healing or for the constant replacement of cells in our blood, skin or intestine. Behind every newly diagnosed malignant tumor in adulthood there is an individual history of probably 20 or more years of tumorigenesis. Therefore, malignant tumor formation often takes time making cancer in most cases to an aging-related disease that we seem not to be able to evade. However, tumorigenesis is dependent on multiple environmental influences, many of which we have under control by lifestyle decisions, such as retaining from smoking, selecting healthy food and being physically active. Thus, cancer preventive interventions are the most effective way to fight against cancer. This textbook wants not only to describe basic mechanisms leading to cancer but also to provide the readers with a more holistic view including cancer surveaillance mechanisms of the immune system. We will place these insights in the context of the personal consequences of everyone’s lifestyle decisions. The content of the book is linked to the lecture course in “Cancer Biology”, which is given by Prof. Carlberg since 2005 at the University of Eastern Finland in Kuopio. Moreover, biological processes explained in this book will be set into a clinical context using the experience of Dr. Velleuer in the daily care in oncology. This book also relates to the textbooks “Mechanisms of Gene Regulation: How Science Works” (ISBN 978-3-030-52321-3), “Human Epigenetics: How Science Works” (ISBN 978-3-030-22907-8) and “Nutrigenomics: How Science Works” (ISBN 978-3-030-36948-4), the studying of which may be interesting to readers who like to get more detailed information.
    Type of Medium: Online Resource
    Pages: XVII, 167 p. 72 illus., 71 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030756994
    DDC: 571.978
    Language: English
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  • 148
    Keywords: Human physiology. ; Immune system. ; Cellular signal transduction. ; Respiratory organs. ; Physiology. ; Diseases. ; Human Physiology. ; Immune Cell Signalling. ; Respiratory Physiology. ; Diseases.
    Description / Table of Contents: Chapter 1. Introduction to Lung Diseases -- Chapter 2. Targeting molecular and cellular mechanisms in asthma.-Chapter 3. Various cellular and molecular axis involved in the pathogenesis of asthma -- Chapter 4. Targeting molecular and cellular mechanisms in steroid resistant asthma -- Chapter 5. Targeting molecular and cellular mechanisms in chronic obstructive pulmonary disease -- Chapter 6. Probing the cellular and molecular mechanisms underlying in the pathogenesis of Chronic Obstructive Pulmonary Disease (COPD) -- Chapter 7. Chronic obstructive pulmonary disease: Molecular basis of pathogenesis and targeted therapeutic approaches -- Chapter 8. Exploring the ‘dormancy-activation switch’ in the tumour microenvironment for metastatic lung cancer: The possible role of microRNA -- Chapter 9. Therapeutic strategies targeting signalling pathways in lung cancer -- Chapter 10. Modulation of signalling pathways by immunotherapeutics in lung cancer -- Chapter 11. Underpinning the Cellular and Molecular Mechanisms with Nanotheronstics for Lung Cancer -- Chapter 12. Targeting molecular and cellular mechanisms in Idiopathic Pulmonary Fibrosis.-Chapter 13. A refined approach to target the molecular and cellular mechanisms in pulmonary fibrosis.-Chapter 14. Targeting molecular and cellular mechanisms in tuberculosis -- Chapter 15. Cellular and Molecular Mechanisms of Repurposed antidiabetic drug as adjunctive treatment for tuberculosis -- Chapter 16. Targeting host and bacterial signaling pathways in tuberculosis: An effective strategy for the development of novel anti-tubercular therapies -- Chapter 17. Targeting molecular and cellular mechanisms in pulmonary hypertension -- Chapter 18. Targeting molecular and cellular mechanisms in pulmonary arterial hypertension -- Chapter 19. Potential cellular targets associated with the signaling and therapeutics of the pulmonary hypertension -- Chapter 20. Targeting molecular and cellular mechanisms in influenza A virus infections -- Chapter 21. Understanding the Biology of Non-typeable Haemophilus influenzae in Chronic Obstructive Pulmonary Disease through the Lens of Genomics -- Chapter 22. Targeting molecular and cellular mechanisms in rhinovirus infection -- Chapter 23. Targeting molecular and cellular mechanisms in respiratory syncytial virus (RSV) infection -- Chapter 24. Targeting molecular and cellular mechanisms SARS-CoV2 novel corona (COVID-19) virus infection -- Chapter 25. Underpinning the rudimentary mechanisms involved in the pathogenesis of SARS-CoV2 (COVID-19) in human lung cells -- Chapter 26. Targeting molecular and cellular mechanisms in SARS-CoV2 novel corona (COVID-19) virus infection -- Chapter 27. Special features of human lung ACE2 sensitivity to SARS CoV-2 spike glycoprotein -- Chapter 28. Implications of Phosphoinositide 3-kinase (PI3K) Signalling in cellular and molecular mechanisms of respiratory diseases -- Chapter 29. The role of the cholinergic system in lung diseases -- Chapter 30. The Nrf2-Keap1 signaling pathway in lung cancer -- Chapter 31. Role of Toll like receptor (LTR) in molecular and cellular mechanism of respiratory diseases -- Chapter 32. Biomarkers of Oxidative Stress -- Chapter 33. Targeting chronic lung diseases using advanced drug delivery systems -- Chapter 34. Plant based chemical moieties targeting cellular signalling pathways in chronic lung diseases -- Chapter 35. Role of phytoconstituents in targeting cytokines for managing pathophysiology of lung diseases -- Chapter 36. Targeting Cellular Signaling Pathways in Lung Cancer and Role of Phytochemicals as Novel Therapeutic Approach -- Chapter 37. Natural compounds targeting major signalling pathways in lung cancer -- Chapter 38. Drug delivery in respiratory diseases: Current opportunities, Molecular and cellular mechanism, and Future challenges -- Chapter 39. Future prospects and challenges in targeting cellular and molecular mechanisms in respiratory diseases.
    Abstract: The book comprehensively reviews and provides detailed insight into the cellular and molecular signalling mechanisms involved in pathophysiology of various respiratory diseases, towards developing effective therapeutic strategies in the management and treatment of lung disease. It also covers promising advances in the field of therapeutics that could lead to novel clinical therapies capable of preventing or reversing the disease features including novel strategies for targeting chronic lung diseases using advanced drug delivery systems. Importantly, the book examines the significance and relevance of the plant extracts and their constituents with therapeutic efficiencies against lung diseases. As such, the book offers a blend of translational, biological, chemical, and drug delivery aspects relevant to respiratory diseases, thus, offering a valuable resource for pulmonologists and translational researchers working in the field of pulmonary biology and respiratory medicine.
    Type of Medium: Online Resource
    Pages: XIV, 926 p. 149 illus., 107 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789813368279
    DDC: 612
    Language: English
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  • 149
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    Cham :Springer International Publishing :
    Keywords: Invertebrates. ; Parasitology. ; Veterinary microbiology. ; Invertebrate Zoology. ; Parasitology. ; Veterinary Microbiology.
    Description / Table of Contents: 1.Origin and evolution of Triatominae -- 2. Taxonomy -- 3. Speciation Processes in Triatominae -- 4. Chromosome structure and evolution of Triatominae: A review -- 5. Embryonic development of the kissing bug Rhodnius prolixus -- 6. Anatomy of the nervous system of triatomines -- 7. Biogenic monoamines in the control of triatomine physiology with emphasis on Rhodnius prolixus -- 8. Structure and physiology of the neuropeptidergic system of triatomines -- 9. Sensory biology of triatomines -- 10. The behaviour of kissing-bugs -- 11. Features of interaction between triatomines and vertebrates based on bug feeding parameters -- 12. Blood Digestion in Triatomine Insects -- 13. The physiology of sperm transfer and egg production in vectors of Chagas disease with particular reference to Rhodnius prolixus -- 14. The Immune System of Triatomines -- 15. Interaction of triatomines with their bacterial microbiota and trypanosomes -- 16. The ecology and natural history of wild Triatominae in the Americas -- 17. Eco-epidemiology of vector-borne transmission of Trypanosoma cruzi in domestic habitats -- 18. Chagas Disease Vector Control -- 19. Insecticide resistance in triatomines -- 20. Perspectives in triatomine biology studies: “Omics”- based approaches.
    Abstract: This book aims to present updated knowledge on various aspects of the natural history, biology, and impact of triatomines to all interested readers. Each chapter will be written by authorities in the respective field, covering topics such as behavior, neurophysiology, immunology, ecology, and evolution. The contents will consider scientific, as well as innovative perspectives, on the problems related to the role of triatomine bugs as parasite vectors affecting millions in the Latin American region.
    Type of Medium: Online Resource
    Pages: XXX, 620 p. 62 illus., 37 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030645489
    Series Statement: Entomology in Focus, 5
    DDC: 592
    Language: English
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  • 150
    Keywords: Cytology. ; Developmental biology. ; Zoology. ; Biochemistry. ; Evolution (Biology). ; Psychobiology. ; Human behavior. ; Cell Biology. ; Developmental Biology and Stem Cells. ; Zoology. ; Chemical Biology. ; Evolutionary Biology. ; Behavioral Neuroscience.
    Description / Table of Contents: Part 1 Pigments and pigment organelles -- 1 Pigments in insects -- 2 Melanins in vertebrates -- 3 Body color expression in birds -- 4 Pigments in teleosts and their biosynthesis -- 5 Bioluminescence and Pigments -- Part 2 Pigment cell and patterned pigmentation -- 6 Development of melanin-bearing pigment cells in birds and mammals -- 7 Pigment cell development in teleosts -- 8 Pigment patterning in teleosts -- 9 Theoretical studies of pigment pattern formation -- 10 Evolution of Pigment Pattern Formation in Teleosts -- 11 Mechanisms of feather structural coloration and pattern formation in birds -- 12 Mechanism of color pattern formation in insects -- Part 3 Color changes -- 13 Physiological and Morphological Color Changes in Teleosts and in Reptiles -- 14 Color change in cephalopods -- 15 Physiological and biochemical mechanisms of insect color change towards understanding molecular links.
    Abstract: This book comprehensively summarizes the biological mechanisms of coloration and pattern formation of animals at molecular and cellular level, offering up-to-date knowledge derived from remarkable progress in the last 10 years. The brilliant coloration, conspicuous patterns and spectacular color changes displayed by some vertebrates and invertebrates are generally their strategies of the utmost importance for survival. Consists of mainly three parts, starts with introductory chapter, such as Pigments and Pigment Organelles, Developmental Genetics of Pigment Cell Formation, Adult Pigment Patterns, and Color Changes, this book introduces new pigment compounds in addition to classically known pigments and organelles, explains how the generation of multiple types of pigment cell is genetically controlled, describes the mechanisms underlying the zebrafish stripe formation as well as other animals and also summarizes the mechanism of physiological and morphological color changes of teleost, amphibian and cephalopod. Written by experts in the field, this book will be essential reading for graduate students and researchers in biological fields who are interested in pigmentation mechanisms of animals.
    Type of Medium: Online Resource
    Pages: XII, 472 p. 192 illus., 153 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811614903
    DDC: 571.6
    Language: English
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  • 151
    Keywords: Nervous system Surgery. ; Neuropsychology. ; Neurology . ; Neurosurgery. ; Neuropsychology. ; Neurology.
    Description / Table of Contents: Foreword -- Preface -- Part I: Sensorimotor and visuo-spatial functions -- 1. Motor control -- 2. Vision -- 3. FEF -- 4. Spatial cognition -- Part II: Language functions -- 5. Lexical access -- 6. Spontaneous speech -- 7. Reading -- 8. Writing -- 9. Repeating -- 10. Syntactic abilities -- 11. Verbs versus nouns naming -- 12. Verbal short-term memory -- 13. Proper names retrieval -- 14. Bilingual patients -- Part III: Higher-order functions -- 15. From verbal to non-verbal semantics -- 16. Inhibition -- 17. Set-shifting -- 18. Social cognition -- 19. Multitask mapping -- Part IV: Prospects -- 20. Creativity -- 21. Psychiatric and behavorial traits -- 22. Awake surgery in patients with poor abilities of verbal communication -- 23. Can we map inner speech? -- 24. Beyond tasks: when experience shapes intuition.
    Abstract: This book aims to give the state-of-the-art of intraoperative brain function mapping for resection of brain tumors in awake conditions, and to become a reference for acquiring the fundamental expertise necessary to select the right intraoperative task at the right time of the surgery. The chapters, all focused on a specific brain function, are divided in 4 parts: sensori-motor and visuo-spatial functions, language functions, higher-order functions, and prospects. Each chapter follows the same outline, including a brief review of the current knowledge about the networks sustaining the function in healthy subjects, the description of the intraoperative tasks designed to monitor the function, a review of the literature describing the deficits in that function after surgery, and a critical appraisal of the benefit provided by intraoperative mapping of that function.
    Type of Medium: Online Resource
    Pages: XIV, 421 p. 93 illus., 90 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030750718
    DDC: 617.48
    Language: English
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  • 152
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Cancer. ; Diseases. ; Immunology. ; Bioinformatics. ; Cancer Biology. ; Diseases. ; Immunology. ; Bioinformatics.
    Description / Table of Contents: Chapter 1. Obesity induced chronic low-level inflammation and cancers -- Chapter 2. Adipose tissue produced estrogen as risk factor for cancers -- Chapter 3. Insulin and Insulin-like growth factor-1 associated cancers.-Chapter 4. Adipokines play important role in cell proliferation and antiproliferation -- Chapter 5. mTOR and AMP-activated protein kinase in obesity and cancer -- Chapter 6. Immune response and oxidative stress in obesity induced cancer -- Chapter 7. Role of gene polymorphism in obesity and cancer -- Chapter 8. Therapeutic role of green tea in obesity and cancer -- Chapter 9. Effect of dietary phytochemicals in obesity and cancer -- Chapter 10. Resveratrol as anti-obesity and anticancer agent -- Chapter 11. EGCG as anti-obesity and anticancer agent -- Chapter 12. miRNAs as therapeutic target in obesity and cancer -- Chapter 13. In silico updates on lead identification for obesity and cancer -- Chapter 14. In vivo models for obesity and obesity related carcinogenesis -- Chapter 15. Estrogen signaling based current and potential therapies against obesity and related diseases -- Chapter 16. Autophagy at the crossroad of obesity mediated cancer progression.
    Abstract: This book highlights the concordance between signaling pathways that are involved in obesity and cancer cross-talks. It describes the role of cytokines, chemokines, growth factors, insulin, and adipokines in the development of obesity-associated cancers. The book reviews the role of inflammatory signaling pathways such as estrogen-mediated signaling, mTOR and AMP-activated protein kinase pathway and the involvement of adaptive and innate immunity, oxidative stress, gene polymorphism, dietary phytochemicals, and miRNAs in obesity and cancer. In addition, it covers the latest research on the drugs and natural therapeutic agents that target obesity-induced cancers and discusses various in vivo models for studying obesity and obesity-associated cancer. Lastly, it analyses the role of genetic polymorphisms in the obesity-related genes that influence cancer development. The book is a useful resource for researchers in the field of cancer, pharmacology, food chemistry, and clinical biochemistry. .
    Type of Medium: Online Resource
    Pages: IX, 361 p. 38 illus., 23 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811618468
    DDC: 571.978
    Language: English
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  • 153
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Artificial intelligence. ; Artificial Intelligence.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Literature Review -- Chapter 3. Data Analysis -- Chapter 4. SynTime: Token Types and Heuristic Rules -- 5. TOMN: Constituent-based Tagging Scheme -- Chapter 6. UGTO: Uncommon Words and Proper Nouns -- Chapter 7. Conclusion and Future Work.
    Abstract: This book presents a synthetic analysis about the characteristics of time expressions and named entities, and some proposed methods for leveraging these characteristics to recognize time expressions and named entities from unstructured text. For modeling these two kinds of entities, the authors propose a rule-based method that introduces an abstracted layer between the specific words and the rules, and two learning-based methods that define a new type of tagging scheme based on the constituents of the entities, different from conventional position-based tagging schemes that cause the problem of inconsistent tag assignment. The authors also find that the length-frequency of entities follows a family of power-law distributions. This finding opens a door, complementary to the rank-frequency of words, to understand our communicative system in terms of language use.
    Type of Medium: Online Resource
    Pages: XIX, 96 p. 17 illus., 11 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030789619
    Series Statement: Socio-Affective Computing, 10
    DDC: 006.3
    Language: English
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  • 154
    Keywords: Bioinformatics. ; Biology Technique. ; Life sciences. ; Bioinformatics. ; Computational and Systems Biology. ; Biological Techniques. ; Life Sciences.
    Description / Table of Contents: Chapter 1. Prelusion Significance of Livestock -- Chapter 2. Mass Balance concept in Livestock Farming -- Chapter 3. Goat and Sheep Farming -- Chapter 4. Cattle and Buffaloes Farming -- Chapter 5. Factors Influencing Livestock Way of Life -- Chapter 6. Sustainable Livestock Farming -- Chapter 7. Conceptual Development of Livestock Supply Chain Management.
    Abstract: Basic principles of applied life sciences such as recombinant DNA technology is used in most life sciences industries marketing bio-formulations for designing more effective protein-based drugs, such as erythropoietin and fast-acting insulin etc. In recent times genetically engineered host cells from mammal, animal and plants are also being used in life sciences industries to manufacture biologics. This book discusses the most basic as well advanced issues on biological products for successfully managing a life sciences industry. It elucidates the life cycle of biological molecules, right from the conceptual development of different types of biopolymers, and their subsequent transfer from the conical flasks in laboratory to life sciences industries for large scale production and marketing. It focuses on sustainable longevity in the life cycle of commercial biopolymers. Cumulative facts and figures in this volume would immensely help in inspiring life sciences industry promoters to monitor value chain transfer process of biologics for better profitability. Additionally, it would serve as a perusal document for the students and researchers interested in entrepreneurial ventures or having their own start-up projects for the commercialization of biologics. .
    Type of Medium: Online Resource
    Pages: XVI, 207 p. 101 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811620515
    Series Statement: New Paradigms of Living Systems, 2
    DDC: 570.285
    Language: English
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  • 155
    Keywords: Agriculture. ; Botany. ; Agriculture. ; Plant Science.
    Description / Table of Contents: Preface -- Part I: Bulbs -- Chapter 1. Traditional and Novel Approaches in Garlic (Allium sativum L.) Breeding (Einat Shemesh-Mayer and Rina Kamenetsky Goldstein) -- Chapter 2. Genetic Improvement of Leek (Allium ampeloprasum L.) (Fevziye Celebi-Toprak and Ali Ramazan Alan) -- Chapter 3. Shallot (Allium cepa L. Aggregatum group) Breeding (Haim D. Rabinowitch) -- Part II: Roots -- Chapter 4. Molecular Breeding Strategies of Beetroot (Beta vulgaris ssp. vulgaris var. conditiva Alefeld) (Farrag F.B. Abu-Ellail, Khaled F.M. Salem, Maysoun M. Saleh, Lina M. Alnaddaf, and Jameel M. Al-Khayri) -- Chapter 5. Carrot (Daucus carota L.) Breeding (Philipp W. Simon) -- Chapter 6. Parsnip (Pastinaca sativa L.) Breeding for the Future (Lauren H.K. Chappell and Adrian J. Dunford) -- Chapter 7. Radish (Raphanus sativus L.): Breeding for Higher Yield, Better Quality and Wider Adaptability (Binod Kumar Singh) -- Chapter 8. Sugar Beet (Beta vulgaris ssp. vulgaris L.) Improvement with Next-generation Breeding Technology (Chiara De Lucchi, Enrico Biancardi, George Skaracis, Marco De Biaggi, Ourania Pavli, Samathmika Ravi, Claudia Chiodi, Chiara Broccanello, and Piergiorgio Stevanato) -- Chapter 9. Turnip (Brassica rapa var. rapa L.) Breeding (Hesham S. Abdel-Razzak) -- Part III: Tubers -- Chapter 10. Recent Advances in Potato (Solanum tuberosum L.) Breeding (Emre Aksoy, Ufuk Demirel, Allahbakhsh Joiya, Muhammad Abu Bakar Zia, Muhammad Naeem Sattar, Faisal Saeed, Sevgi Çalışkan, and Mehmet Emin Çalışkan) -- Chapter 11. Application of Genome Editing Tools to Accelerate Potato (Solanum tuberosum L.) Breeding (Zafar Iqbal and Muhammad Naeem Sattar) -- Chapter 12. Sweet potato (Ipomoea batatas L.) Breeding (Jolien Swanckaert, Dorcus Gemenet, Noelle L. Anglin, and Wolfgang Grüneberg).
    Abstract: Plant breeders and geneticists are under constant pressure to sustain and expand food production by using innovative breeding strategies and introducing minor crops, which are well adapted to marginal lands, provide a source of nutrition, and have abiotic and biotic stress tolerance, to feed an ever-increasing human population. The basic concept of this book is to examine the use of innovative methods, augmenting traditional plant breeding, towards the improvement and development of new crop varieties, under the increasingly limiting environmental and cultivation factors, to achieve sustainable agricultural production and enhanced food security. Three volumes of the book series Advances in Plant Breeding Strategies were published in 2015, 2016 and 2018, respectively: Volume 1. Breeding, Biotechnology and Molecular Tools; Volume 2. Agronomic, Abiotic and Biotic Stress Traits and Volume 3. Fruits. In 2019, the following four volumes were published: Volume 4. Nut and Beverage Crops, Volume 5. Cereals, Volume 6. Industrial and Food Crops and Volume 7. Legumes. Recent volumes published in 2021 include: Volume 8. Vegetable Crops: Bulbs, Roots and Tubers, Volume 9. Vegetable Crops: Fruits and Young Shoots and Volume 10. Vegetable Crops: Leaves, Flowerheads, Green Pods, Mushrooms and Truffles. This Volume 8, subtitled Vegetable Crops: Bulbs, Roots and Tubers, consists of 12 chapters focusing on advances in breeding strategies using both traditional and modern approaches for the improvement of individual vegetable crops. Chapters are arranged in 3 parts according to the edible vegetable parts. Part I: Bulbs - Garlic, Leek and Shallot; Part II: Roots - Beetroot, Carrot, Parsnip, Radish, Sugar beet and Turnip, Part III: Tubers - Potato and Sweet potato. Each chapter comprehensively reviews the contemporary literature on the subject and reflects the experiences of the authors. Chapters are written by internationally-reputable scientists and subjected to a review process to assure quality presentation and scientific accuracy. Each chapter begins with an introduction covering related backgrounds and provides in-depth discussion of the subject supported with high-quality color photos, illustrations and relevant data. The chapter concludes with recommendations for future research directions, a comprehensive list of pertinent references to facilitate further reading, and appendixes of genetic resources and concerned research institutes. This book series is a valuable resource for advanced students, researchers, scientists, commercial producers and seed companies as well as consultants and policymakers interested in agriculture, particularly in modern breeding technologies.
    Type of Medium: Online Resource
    Pages: XV, 554 p. 105 illus., 86 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030669652
    DDC: 630
    Language: English
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  • 156
    Keywords: Neurosciences. ; Neuroscience.
    Description / Table of Contents: 1. Using electrical stimulation to explore and augment the functions of parietal-frontal cortical networks in primates -- 2. Multi-system benefits of epidural stimulation following spinal cord injury. 3. Neurostimulator for hippocampal memory prosthesis -- 4. Modern approaches to augmenting the brain functions -- 5. Brain machine interfaces within a critical perspective -- 6. An implantable wireless device for ECoG and cortical stimulation -- 7. BCI Performance improvement by special low jitter quasi-steady State VEP paradigm -- 8. Communication with Brain-Computer Interfaces in Medical Decision-Making -- 9. Neuroprotection and neurocognitive augmentation by photobiomodulation -- 10. Avoiding partial sleep - the way for augmentation of brain function -- 11. Augmentation of brain functions by nanotechnology -- 12. The impact of ageing and age-related comorbidities on stroke outcome in animal models and humans -- 13. Diagnostic markers of sub-clinical depression based on functional connectivity -- 14. Transcranial magnetic stimulation in autism spectrum disorders: modulating brainwave abnormalities and behaviors -- 15. Neurofeedback training with concurrent psychophysiological monitoring in children with autism spectrum disorder with comorbid attention deficit/hyperactivity disorder -- 16. Augmentation through interconnection: brain-nets and telemedicine -- 17. Cognitive augmentation via a brain/cloud interface -- 18. Augmentation of neuro-marketing by neural technology -- 19. Augmentation of nutrition by nanotechnology -- 20. Neural spintronics: noninvasive augmentation of brain functions -- 21. Does the power to suppress an action make us free? -- 22. Deep brain stimulation for Parkinson’s disease-future directions for enhancing motor function -- 23. Neuromodulation for gait -- 24. Augmentation and rehabilitation with active orthotic devices -- 25. Effects of rTMS on behavioral and electrocortical measures of error monitoring and correction function in children with autism spectrum disorder -- 26. Affective Virtual Reality Gaming for Autism -- 27. A machine learning approach to automatic phobia therapy with virtual reality -- 28. Vision augmentation by pharmacological enhancement of the visual experience -- 29. Cognitive enhancing substances and the developing brain: risks and benefits -- 30. Pharmacological approaches in the augmentation and recovery of brain function.
    Abstract: This book covers recent advances in the neural technology that produces enhancements for brain function. It addresses a broad range of neural phenomena occurring in the brain circuits for perception, cognition, emotion and action, representing the building blocks of the behavior and mind. Augmentation of brain function is achieved using brain implants for recordings, stimulation and drug delivery. Alternative methods include employing brain-machine interfaces, as well as noninvasive activation of certain brain areas. Existing methods of brain augmentation are evaluated, and new approaches are introduced. Brain circuitry and neuronal mechanisms that are candidates for augmentation are discussed. This volume provides novel insights into brain disorders, and new devices for brain repair. Information in this book is relevant to researchers in the field of neuroscience, engineering, and clinical practice. Philosophical and ethical implications of brain augmentation are also addressed. “This impressive book by leading experts in neuroscience and neuroengineering lays out the future of brain augmentation, in which the human mind and machine merge, leading to a rapid exponential growth of the power of humanity.” – Ray Kurzweil "This book employs a holistic approach in covering the recent advances in the fields of neuroscience, neuroinformatics, neurotechnology and neuro-psycho-pharmacology. Each chapter of the book covers major aspects of modern brain research in connection with the human mind and behavior, and is authored by researchers with unique expertise in their field. " – Ioan Dumitrache “This book presents compelling perspectives on what interactive neuroscience will look like in the future, delving into the innovatory ideas of a diverse set of neuroscientists, and speculating on the different ways computer chips implanted in the brains of humans can effect intelligence and communication.” – György Buzsáki.
    Type of Medium: Online Resource
    Pages: XXII, 747 p. 189 illus., 153 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030545642
    Series Statement: Contemporary Clinical Neuroscience,
    DDC: 612.8
    Language: English
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  • 157
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Botanical chemistry. ; Food science. ; Plant physiology. ; Biotechnology. ; Plant Biochemistry. ; Food Science. ; Plant Physiology. ; Biotechnology.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Search of Sweeteners, their general classification, synthesis, and saccharide sweeteners plant - animal interphases -- Chapter 3. Molecular basis of sweetness and recent concepts, An ideal sweetener and saccharide and non-saccharide sweet principles qualifying it -- Chapter 4. Saccharide sweet (SS) principles, classification and structural and functional details of SS sweeteners and plants -- Chapter 5. Non saccharide super sweet principles, their general characteristics, outline of synthesis, classification, ecological significance and eco-friendly adherence -- Chapter 6. Perillartine (Mono-terpenoid) -- Chapter 7. Steviosides (Diterpenoids) -- Chapter 8. Triterpenoids -- Chapter 9. Hernandulcin: (Sesquiterpene) -- Chapter 10. Falvonoid Super Sweet Principles Dihydrochalcone -- Chapter 11. PHYLLODULCIN -- Chapter 12. Osladin, Polypodoside A, B, and C (Steroidal saponins) -- Chapter 13. Monatin:(Super Sweet Amino acid) -- Chapter 14. Super sweet and taste modifier proteins -- Chapter 15. Vegetal Taste modifiers -- Chapter 16. Eco-Physiological difference between sacchariferous sweet (SS) and non sacchariferous super sweet (NSSS) principles and Plants -- Chapter 17. Molecular approaches for the improvement of Non sacchariferous super sweet (NSSS) plants -- Chapter 18. Commercial Production of natural NSSS sweeteners-A concised sketch.
    Abstract: This book gathers the latest information on various kinds of natural, plant-based sweet and super sweet sweeteners. A book on alternative, natural sweeteners with zero or very few calories is extremely timely and useful, especially in light of the decreasing amount of cultivable land, ever-increasing demand for sucrose, and the well-known risks of sugar consumption. Every year, more than five million people die due to diabetes and diabetes-associated diseases like cardiovascular conditions, kidney disorders, liver cancer, etc. This book describes the use of natural non-saccharide super sweet (NSSS) principles to avoid such maladies. Readers will gain an in-depth understanding of various sweeteners, the molecular basis of sweetness, sweeteners’ general classification, plant sources, etc. In turn, the book focuses on the propagation, cultivation and conservation of NSSS plants (NSSSP) and extraction of super sweet principles and granting of Generally Recognised As Safe (GRAS) certificates for sweeteners. The closing chapter describes the eco-physiological difference between sacchariferous sweet and non-sacchariferous super sweet plants and principles. This book will be of great interest to researchers, professors, graduate students and practitioners in the fields of food science, nutrition, ayurveda, plant physiology, unani, chemotaxonomy, naturopathy, biochemistry and plant breeding. It will also be of interest to industry and alternative sweetener manufacturers.
    Type of Medium: Online Resource
    Pages: XXIX, 773 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789813363502
    DDC: 572.2
    Language: English
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  • 158
    Keywords: Immunology. ; Molecular biology. ; Nutrition   . ; Cytology. ; Biology. ; Immunology. ; Molecular Biology. ; Nutrition. ; Cell Biology. ; Biological Sciences.
    Description / Table of Contents: Chapter 1. Nanotechnology based bacterial immunotherapy -- Chapter 2. Immunomodulatory properties of nutraceuticals and functional foods -- Chapter 3. Immunoregulatory bioactive phytoconstituents- recent trends and future challenges -- Chapter 4. Plant derived immunomodulators and immune system -- Chapter 5. Polyphenols and its effect on immune system -- Chapter 6. Mineral nutraceuticals and immunity enhancement -- Chapter 7. Nutraceuticals as disease preventive food and immunity boosters -- Chapter 8. Current and Future prospects of flavonoids for human Immune system -- Chapter 9. Resveratrol and immunomodulation -- Chapter 10. Immunomodulation impact of curcumin and its derivative as a natural ingredient -- Chapter 11. Colchicine and andrographolide as natural immunomodulators -- Chapter 12. Immune booster property of epigallocatechin-3-gallate and catechin -- Chapter 13. Recent advances of nutraceutical and functional foods in immune health -- Chapter 14.Therapeutic effects of Withania somnifera-an overview with special focus on Alzheimer’s disease and infertility among youth.
    Abstract: This book provides valuable coverage on various immunomodulatory research associated with nutraceutical studies, from plant to animal and marine sources. The book focuses on the various properties of nutraceutical and functional foods, from dietary fibers to fungus, marine sources, ginseng, and several others. Its content is also dedicated to the nutraceutical potential and applications of these modulators. The first section of this book focuses mainly on the recent developments in nutraceutical and functional food associated with various immunomodulators. The next section covers the micronutrients and macronutrients level in order to share important data and help readers gain a basic understanding of the techno-functional, nutraceutical potential and applications of nutritional treatment under specific disease conditions. A detailed overview providing the structural and functional properties related to immunomodulators will be highly beneficial for academics and advanced-level students in immunology, food science, clinical medicine, and life sciences.
    Type of Medium: Online Resource
    Pages: XII, 348 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811925078
    DDC: 571.96
    Language: English
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  • 159
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Toxicology. ; Machine learning. ; Artificial intelligence. ; Toxicology. ; Machine Learning. ; Artificial Intelligence.
    Description / Table of Contents: Machine Learning and Deep Learning Promotes Predictive Toxicology for Risk Assessment of Chemicals -- Multi-Modal Deep Learning Approaches for Molecular Toxicity prediction -- Emerging Machine Learning Techniques in Predicting Adverse Drug Reactions -- Drug Effect Deep Learner Based on Graphical Convolutional Network -- AOP Based Machine Learning for Toxicity Prediction -- Graph Kernel Learning for Predictive Toxicity Models -- Optimize and Strengthen Machine Learning Models Based on in vitro Assays with Mecha-nistic Knowledge and Real-World Data -- Multitask Learning for Quantitative Structure-Activity Relationships: A Tutorial -- Isalos Predictive Analytics Platform: Cheminformatics, Nanoinformatics and Data Mining Applications -- ED Profiler: Machine Learning Tool for Screening Potential Endocrine Disrupting Chemicals -- Quantitative Target-specific Toxicity Prediction Modeling (QTTPM): Coupling Machine Learning with Dynamic Protein-Ligand Interaction Descriptors (dyPLIDs) to Predict Androgen Receptor-mediated Toxicity -- Mold2 Descriptors Facilitate Development of Machine Learning and Deep Learning Models for Predicting Toxicity of Chemicals -- Applicability Domain Characterization for Machine Learning QSAR Models -- Controlling for Confounding in Complex Survey Machine Learning Models to Assess Drug Safety and Risk. .
    Abstract: This book is a collection of machine learning and deep learning algorithms, methods, architectures, and software tools that have been developed and widely applied in predictive toxicology. It compiles a set of recent applications using state-of-the-art machine learning and deep learning techniques in analysis of a variety of toxicological endpoint data. The contents illustrate those machine learning and deep learning algorithms, methods, and software tools and summarise the applications of machine learning and deep learning in predictive toxicology with informative text, figures, and tables that are contributed by the first tier of experts. One of the major features is the case studies of applications of machine learning and deep learning in toxicological research that serve as examples for readers to learn how to apply machine learning and deep learning techniques in predictive toxicology. This book is expected to provide a reference for practical applications of machine learning and deep learning in toxicological research. It is a useful guide for toxicologists, chemists, drug discovery and development researchers, regulatory scientists, government reviewers, and graduate students. The main benefit for the readers is understanding the widely used machine learning and deep learning techniques and gaining practical procedures for applying machine learning and deep learning in predictive toxicology. .
    Type of Medium: Online Resource
    Pages: XIX, 635 p. 149 illus., 124 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031207303
    Series Statement: Computational Methods in Engineering & the Sciences,
    DDC: 615.90072
    Language: English
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  • 160
    Keywords: Biology. ; Biotechnology. ; Biophysics. ; Renewable energy sources. ; Biological Sciences. ; Biotechnology. ; Biophysics. ; Renewable Energy.
    Description / Table of Contents: Chapter 1. Introduction -- Chapter 2. Biotechnology and Its Connection to Renewable Energies: Biofuels Production -- Chapter 3. Biotechnological Formation of Biogas -- Chapter 4. Biotechnology in Bioethanol Generation -- Chapter 5. Biological Methods for Diesel Formation -- Chapter 6. Biotechnological-based Production of Bio-Oil and Vegetable Oil -- Chapter 7. Biotechnology in Hydrogen Generation -- Chapter 8. Global Conclusions and Future Perspectives.
    Abstract: This book approaches biofuels from a new biotechnological perspective with the aim of equipping researchers with a thorough, up-to-date understanding of biofuel research and related technologies. Topics include biomethane, bioethanol, biobutanol, biomass, hydrolysis, bio-oil, microbiology, and many more. Biofuel research has evolved mechanisms to advance their utilization and their application in our system. The chapters will provide concise and up-to-date information to aid our understanding of biotechnology-related implications of biofuels development and its advancements. Readers in the areas of bioengineering, sustainability, renewable energies and biotechnology will find this work useful to widen their knowledge and perspectives on biofuels.
    Type of Medium: Online Resource
    Pages: X, 147 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811991875
    Series Statement: Interdisciplinary Biotechnological Advances,
    DDC: 570
    Language: English
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  • 161
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Botany. ; Plant anatomy. ; Biodiversity. ; Plant Science. ; Plant Anatomy and Morphology. ; Biodiversity.
    Description / Table of Contents: Part I – User manual and architectural concepts. Chapter 1. Introduction -- Chapter 2. How to use this book 6 -- Chapter 3. Architectural concepts and key to the models -- Part II. Identification keys -- Chapter 4. Key to the groups of families of trees and shrubs (groups 1 to 52) -- Chapter 5. Keys to families of trees and shrubs -- Chapter 6. Supplementary keys -- Chapter 7. Keys to the groups of families of lianas and woody epiphytic (groups 53 to 57) -- Chapter 8. Keys to families of lianas and woody epiphytes -- PART III. Description of the families -- Chapter 9. Acanthaceae to Asteraceae -- Chapter 10. Bignoniaceae to Buxaceae -- Chapter 11. Cactaceae to Cycadaceae -- Chapter 12. Dichapetalaceae to Dipterocarpaceae -- Chapter 13. Ebenaceae to Euphorbiaceae -- Chapter 14. Fagaceae -- Chapter 15. Gentianaceae to Goupiaceae -- Chapter 16. Hamamelidaceae to Humiriaceae -- Chapter 17. Icacinaceae s.l. to Irvingiaceae -- Chapter 18. Juglandaceae -- Chapter 19. Lamiaceae to Lythraceae -- Chapter 20. Magnoliaceae to Myrtaceae -- Chapter 21. Nyctaginaceae,- Chapter 22. Ochnaceae to Oxalidaceae -- Chapter 23. Pandaceae to Putranjivaceae -- Chapter 24. Rhabdodendraceae to Rutaceae -- Chapter 25. Sabiaceae to Symplocaceae -- Chapter 26. Tetramelaceae to Torricelliaceae -- Chapter 27. Ulmaceae s.l. to Urticaceae -- Chapter 28. Verbenaceae to Vochysiaceae -- Chapter 29. Zygophyllaceae s.l -- Chapter 30. Herbaceous versus arborescent habit in the families and orders of flowering plants - evolutionary trends.
    Abstract: This book provides an identification system permitting recognition of plant families in all seasons by means of morphological and macroanatomical features which are easily observable, such as bark, exudates, stems and leaves characters. Studies of forest vegetation may differ in their underlying objectives, but they all require taxonomic knowledge. The process of taxonomy begins with an inventory of the flora, which has been based to a large extent on reproduction-related organs, such as flowers and fruits. But, those are often difficult to observe and may not exist in the field at a given time. Unlike most such guides or keys, this book can be used anywhere in the tropics and provides, in a straightforward two or three-step process, identification to the level of families, which are now circumscribed according to molecular as well as morphological characters in the universally accepted scheme of the Angiosperm Phylogeny Group. Plant architecture is not a prerequisite theme for plant identification; however, we think that an introduction to this subject is not out of place in this book (architectural traits are taxonomically sound): it is now time for botanists working in the tropics to have an idea on how the whole organism keeps growing. Within the family accounts, there is information concerning important economic plants with notes on the larger genera and, particularly helpfully, discussion of families readily confused and how to separate them. Descriptions of the families rely on short diagnosis bolstered by many photographic pictures, lines drawings and extracts from the author’s field books, all showing features of plants as they are found in the forest.
    Type of Medium: Online Resource
    Pages: XVII, 494 p. 909 illus., 850 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031059421
    DDC: 580
    Language: English
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  • 162
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Veterinary medicine. ; Agriculture. ; Physiology. ; Agricultural genome mapping. ; Animal welfare Moral and ethical aspects. ; Veterinary Science. ; Agriculture. ; Animal Physiology. ; Agricultural Genetics. ; Animal Ethics.
    Description / Table of Contents: Chapter 1. Putting Smart into Nutrition -- Chapter 2. Mozatching Feed Characteristics to Animal Requirements Through Plant Breeding -- Chapter 3. Circular Feed Production and Consumption in The Context Of Smart Animal Nutrition -- Chapter 4. Assessment of The Nutritive Value of Individual Feeds and Diets by Novel Technologies -- Chapter 5. Large Scale Phenotyping and Genotyping: State of The Art and Emerging Challenges -- Chapter 6. Mathematical and Statistical Approaches to The Challenge of Forecasting Animal Performance for The Purposes of Precision Livestock Feeding -- Chapter 7. Smart Pig Nutrition in the Digital Era -- Chapter 8. Smart Poultry Nutrition -- Chapter 9. Advanced Technology in Aquaculture – Smart Feeding in Marine Fish Farms -- 10. Smart Nutrition of Extensively Kept Ruminants -- Chapter 11. The Potential Contribution of Smart Animal Nutrition in Reducing The Environmental Impacts of Livestock Systems.
    Abstract: This book highlights the latest findings and techniques related to nutrition and feed efficiency in animal agriculture. It addresses the key challenges facing the nutrition industry to achieve high animal productivity with minimal environmental impact. The concept of smart nutrition involves the use of smart technologies in the feeding and management of livestock. The first chapters focus on advances in biological fields such as molecular agriculture and genotype selection, as well as technologies that enhance or enable the collection of relevant information. The next section highlights applications of smart nutrition in a variety of livestock systems, ranging from intensive indoor housing of broilers and pigs to extensive outdoor housing of cattle and sheep, and marine fish farms. Finally, because of the worldwide attention to this issue, the authors address the environmental consequences. This work, which takes a serious look at how nutrition can be used to improve sustainability in animal agriculture, is a key literature for readers in animal and veterinary sciences, the food industry, sustainability research, and agricultural engineering.
    Type of Medium: Online Resource
    Pages: VIII, 336 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031225840
    Series Statement: Smart Animal Production, 1
    DDC: 636.089
    Language: English
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  • 163
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Agriculture. ; Agriculture.
    Description / Table of Contents: Chapter 1 The Role of Skepticism in Science? -- Chapter 2 Warnings for Skeptics -- Chapter 3 Photosynthesis -- Chapter 4 Seed Number -- Chapter 5 Nitrogen Use Efficiency -- Chapter 6 Water Use Efficiency -- Chapter 7 Water Loss -- Chapter 8 Unconfirmed Field Observations (UFOs).
    Abstract: Global food production and climate change among other concerns are societal issues that require major research input from crop science. While suggestions are abundant on how crop science can help to resolve these issues, many of the suggestions come from people who are not actually familiar with the challenges and requirements to modify crop plants grown under field conditions to achieve the necessary improvements. Efforts to alter a gene or even several genes have very rarely proven successful in having impact on crop production under realistic field conditions. This lack of success has not been addressed head on. This book serves as a reminder to crop scientists and others that open, clear-minded assessments of the entirety of evidence concerning a hypothesis is required before making claims of possible increases in crop performance. This attitude of skepticism is not a negative attitude but rather an employment of the cornerstone of scientific investigation based on formation and evaluation of hypotheses. Skeptical analyses are to be presented in the book on some of the common suggestions for improving crop plants. The six specific topics to be addressed are photosynthesis, seed number, nitrogen use efficiency, water use efficiency, crop water loss, and unconfirmed field observations. Each of the topics in this book, will first be reviewed to present the origins of the popular assumptions about how specific plant modification will result in improved crop performance. The review of the background information will be followed by an examination of the evidence, logic, and predicted outcomes for the assumed benefits of the modifications. Finally, each chapter will offer novel, alternate approaches to plant modification that have documented support for positively impacting crop performance. The book will not be written in specialized, detail language but offer access for those with a wide range of interests in options for increasing crop production in the future. The goal of the book is to provide information that is useful to those with interests ranging from climatologist to food-oriented sociologists. Of course, the topics covered will be of direct interest to those studying plant sciences, particularly crop scientists. The hope is to challenge a reader to re-examine some of her/his assumptions about crop improvement and approach the topic with a renewed practice of skepticism in formulating and evaluating hypotheses. .
    Type of Medium: Online Resource
    Pages: VI, 66 p. 32 illus., 17 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031144141
    Series Statement: SpringerBriefs in Agriculture,
    DDC: 630
    Language: English
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  • 164
    Keywords: Food science. ; Sustainability. ; Family-owned business enterprises. ; Economics. ; Food Science. ; Sustainability. ; Family Business. ; Economics.
    Description / Table of Contents: Chapter 1 Bread Industry Sustainability Life Cycle Assessment -- Chapter 2 Product Environmental Footprint and Bread Industry -- Chapter 3 Life Cycle Assessment and Product Environmental Footprint - recommendations for integral optimization of economic and environmental performance -- Chapter 4 Ensuring sustainability of baking industry in North Macedonia -- Chapter 5 Sustainability approach of the baking industry along the food supply chain -- Chapter 6 Sustainability assessment of the baking industry complying with standards requirements: a case of Romania -- Chapter 7 Across American overview on sustainability approach throughout baking industry: An analytical-descriptive approach -- Chapter 8 Asian Overview on Sustainability Approach in Baking Industry -- Chapter 9 African Experience in Ensuring Sustainability in Baking -- Chapter 10 Indian experience in ensuring sustainability in baking industry -- Chapter 11 Measuring Baking Business Performance -- Chapter 12 Forming the efficient business model for bakery -- Chapter 13 Assessment of the sustainable competitiveness of agricultural enterprises on the grain market: case of Ukraine -- Chapter 14 Economic viability and sustainability in baking industry/ Simeuna - bread producer with own grain production -- Chapter 15 Impact of Bakery Innovation on Business Resilience Growth -- Chapter 16 Innovation in the commercial system of the small bakery industry -- New business models in food systems for farmers and companies, based on multi-actor approach -- Chapter 18 The role of rural women in bread industry – Job creation and retention in rural areas.
    Abstract: This timely and comprehensive text focuses on important recent advances in applied sustainability in the baking industry, connecting all of the current methods and strategies into a single book. Those involved in bread production will find the latest developments at the theoretical and practical levels, including information and communication requirements, reporting and regulatory aspects, economic and environmentally sustainable business models, supply chain management, life cycle assessment, product and organizational environmental footprints and more. For small bakery business owners to industry leaders and policymakers, governmental authorities, regulatory authorities and standardization bodies, this book offers a compilation of technical information about sustainability in the market for the bakery sector. Baking Business Sustainability Through Life Cycle Management begins by presenting basic information on the life cycle assessment and product environmental footprint of the bread industry, proposing an analysis of sustainability assessment using environmental and social footprints and providing recommendations for integral optimization of economic and environmental performance. A second section focuses on sustainability in the baking industry, providing a regional focus from Europe to the Americas to Africa and Asia. The third section takes a deep look at economic feasibility and efficiency in the bread industry, including the economic viability of different scenarios for bread-based value chains, and forming efficient business models for bakeries. A final section zeroes in on the most up-to-date innovations in the current bakery industry, including the impact of bakery innovation on business resilience growth, commercial systems, and new business models in regional food systems for farmers and companies, based on multi-actor approach. Innovations within the bakery industry are at an all-time high, with new sustainability and economic models being introduced, along with associated market risks. This timely and ambitious text aims to cover all the most recent advances and methods for successful incorporation into bakery businesses. .
    Type of Medium: Online Resource
    Pages: VIII, 313 p. 74 illus., 59 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031250279
    DDC: 641.3
    Language: English
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  • 165
    Keywords: Agriculture. ; Food science. ; Plant biotechnology. ; Agriculture. ; Food Science. ; Plant Biotechnology.
    Description / Table of Contents: Chapter 1. Global scenario of temperate nuts -- Chapter 2. Nutritional composition of temperate nuts -- Chapter 3. Development and selection of rootstocks -- Chapter 4. Cultivars and genetic improvement -- Chapter 5. Improved propagation techniques in temperate nuts -- Chapter 6. Pollination management -- Chapter 7. Mineral nutrition -- Chapter 8. Plant water relations and Irrigation -- Chapter 9. Canopy architecture -- Chapter 10. Biotechnological interventions for improvement of temperate nuts -- Chapter 11. Organic approaches in temperate nuts -- Chapter 12. Shelf life enhancement -- Chapter 13. Package and storage of temperate nuts -- Chapter 14. Physiological disorders -- Chapter 15. Diseases of temperate nuts -- Chapter 16. Integrated pest management of temperate nuts.
    Abstract: This book focuses on the production technology of temperate nuts. It explores cultivar and plant improvement, development and selection of rootstocks, plant–water relations and irrigation, canopy architecture, and postharvest packaging of nut fruits. It also deals with organic approaches, biotechnological interventions, diseases, and pest management. Contributing authors address nut fruits such as walnut, pecan nut, chestnut, and hazel nut on different recent aspects. The development achieved in the fruit sector is indicative of the fact that there is growing demand of fruit produce. Temperate nuts with health benefits and market acceptability have best sources of fat, fiber, protein, and mineral. They provide dietary fiber, potassium, and a variety of health-protective bioactive compounds. Apart from the health benefits, production of temperate nuts improves the economy of the country as these are very good source of income and employment. In addition, there is wide diversification in the production pattern of nuts globally. Increased production technology such as hybrids, high-yielding selections/ varieties, improved propagation techniques, and increased use of fertilizers and manures have brought spectacular increase in the production of nut fruits. This book is of interest to teachers, scientists, researchers, and scholars. Also, the book serves as additional reading material for undergraduate and postgraduate students of agriculture and horticulture. Horticulture nurseries and orchard industries also find this to be a useful read.
    Type of Medium: Online Resource
    Pages: XIII, 385 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811994975
    DDC: 630
    Language: English
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  • 166
    Keywords: Biodiversity. ; Freshwater ecology. ; Marine ecology. ; Grassland ecology. ; Biodiversity. ; Freshwater and Marine Ecology. ; Grassland Ecology.
    Description / Table of Contents: Chapter 1. Fish and fisheries of the temperate Himalayas: An overview and way-forward -- Chapter 2. Fishery resources and ichthyofaunal diversity in the temperate Himalayas -- Chapter 3. Mapping of the Himalayan surface waters using remote sensing and geographic information system tools: An overview of single band-based techniques -- Chapter 4. Fisheries development in open water resources of the temperate Himalaya -- Chapter 5. Diversity and threat to coldwater fishes of river Torsa at the Terai region of West Bengal, India -- Chapter 6. The endangered mighty mahseer (Tor putitora) in the Himalayan waters -- Chapter 7. Aquaculture practices in the temperate Himalayan region -- Chapter 8. Status and prospects of rainbow trout farming in Himalayan waters -- Chapter 9. Fisheries and aquaculture of snow trouts in the Trans-Himalayan region -- Chapter 10. Ornamental Fisheries in Hindu Kush Himalayan Region -- Chapter 11. Recirculating aquaculture system for intensive fish farming in Indian Himalayan region: An overview -- Chapter 12. Coldwater fish nutrition in the Indian Himalayas -- Chapter 13. Molecular characterization and population structure of the important Himalayan fish species -- Chapter 14. Prospects and challenges of molecular interventions for enhancing aquaculture production in the temperate Himalayas -- Chapter 15. An overview of coldwater fish diseases and their control measuresChapter 16. Oomycetes, fungal-like menace in coldwater aquaculture -- Chapter 17. Antimicrobial peptides: An alternative to antibiotics for environment-friendly hill aquaculture -- Chapter 18. Advances in detection techniques for fungus-like organisms of aquaculture importance -- Chapter 19. Nutritional quality and human health benefits of important coldwater fishes of the Indian Himalayas -- Chapter 20. En-route towards aquaponics in coldwater: Identifying the gaps in principles and system design -- Chapter 21. Impact of climate change in temperate fisheries of the Himalayas and possible adaptation approaches -- Chapter 22. Livelihood opportunities with recreational fisheries and ecotourism -- Chapter 23. Design and operational principle of re-circulatory aquaponic system in the Himalayas: Prospects and challenges -- Chapter 24. Farm design and layout for aquaculture operations in the temperate Himalayas -- Chapter 25. Hydroelectric projects: An inevitable challenge in fisheries of the temperate Himalaya.
    Abstract: This book covers all aspects of fisheries and aquaculture of the temperate Himalayas, including fisheries resources, fish biodiversity, aquaculture status, prospects, and potential. It also includes mapping of resources, health and disease management of cultured species, feed and nutritional aspects of the cultured fish species, ornamental fisheries aspects, etc. In addition, it elucidates the recent advances in biotechnological interventions for enhancing fisheries and aquaculture productivity in the region. Essential information on the application of Geo Information System (GIS) for resource mapping, the scope of adopting re-circulatory aquaculture system for productivity enhancement, and trout culture in the Himalayan waters are provided in the book. A detailed account of recreational fisheries and fish-based ecotourism in the temperate Himalayas for generating livelihood has been provided. The impact of climate change on the fisheries of the Himalayas has been dealt with separately. The book also covers the conservation and rehabilitation aspects of endangered species of the region. This book will become a ready reference for the scientists, teachers, researchers, students, policymakers, and other stakeholders for managing fishery resources in the temperate Himalayas.
    Type of Medium: Online Resource
    Pages: XVI, 488 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811983030
    DDC: 333.95
    Language: English
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  • 167
    Keywords: Agricultural biotechnology. ; Botany. ; Agriculture. ; Agricultural Biotechnology. ; Plant Science. ; Agriculture.
    Description / Table of Contents: Chapter 1: Global climate perturbations: sustainable microbial mitigation strategies -- Chapter 2: Soil microflora and their interaction with plants under changing climatic scenarios -- Chapter 3: Beneficial microbial consortia and their role in sustainable agriculture under climate change conditions -- Chapter 4: Unfolding the role of beneficial microbes and microbial techniques on improvement of sustainable agriculture under climatic challenges -- Chapter 5: Microbes and their role in alleviation of abiotic and biotic stress tolerance in crop plants -- Chapterb 6: Plant-microbe interaction and their role in mitigation of heat stress -- Chapter 7: Role of soil microbes against abiotic stresses induced oxidative stresses in plants -- Chapter 8: An overview of the multifaceted role of plant growth promoting microorganisms and endophytes in sustainable agriculture: Developments and prospects -- Chapter 9: Plant growth promoting rhizobacteria (PGPR): an indispensable tool for climate resilient crop production -- Chapter 10: Plant endophyte interactions- a driving phenomenon for boosting plant health in the face of climate change -- Chapter 11: Deciphering the role of growth promoting bacterial endophytes in harmonizing plant health -- Chapter 12: Endophytic microbes and their role in plant health -- Chapter 13: Multitrophic Reciprocity of AMF with Plants and Other Soil Microbes in Relation to Biotic Stress -- Chapter 14: Effect of temperature and defence response on the severity of dry root rot disease in chickpea caused by Macrophomina phaseolina -- Chapter 15: Emerging roles of plant growth promoting rhizobacteria in salt stress alleviation: applications in sustainable agriculture -- Chapter 16: Studies on orchidoid mycorrhizae and mycobionts. associated with orchid plants as plant growth promoters and stimulator in seed germination -- Chapter 17: Current status of mycorrhizal biofertilizer in crop improvement and its future prospects -- Chapter 18: New developments in techniques like metagenomics. metaproteomics for isolation. identification. and characterization of microbes from varied environment -- Chapter 19: Mushroom metagenome: tool to unravel interaction network of plant. mycorrhiza and bacteria -- Chapter 20: Extremophile bacterial and archaebacterial population: metagenomics and novel enzyme reserve -- Chapter 21: Microbial nanotechnology: a biocompatible technology for sustainable and green agriculture practice -- Chapter 22: Bacteriophage Assisted Diagnostics and Management of Plant Diseases.
    Abstract: This book provides a comprehensive understanding of the complex relationship between microbial symbionts and plants in the era of climate change. It focuses on the plant microbiome associated with different plant organs like roots, leaves, stems, fruit, and seeds, and showcases their significant role in the enhancement of crop yield and protection in a sustainable manner. Concomitantly, acumens to the most emerging trends in plant microbial research that includes rhizosphere engineering and metagenomics are also covered in this title. The association of microbial symbionts with the host offers a wide advantage in terms of acclimatization to varied environmental conditions. A large number of microbes such as cyanobacteria, PGPR, endophytes, and AMF have been shown to improve plant growth and production under the effect of various abiotic and biotic stresses. These microbial symbionts secrete several secondary metabolites, signaling molecules, and hydrolytic enzymes that play a multifarious role in improving plant growth and yield. Moreover, the symbionts have been known to regulate the host responses at the molecular level. Bioprospecting these microbial symbionts will provide an alternative to the chemical-based fertilizers and pave the path for the development of biofertilizers. The book is a suitable reading material for undergraduate and postgraduate students, researchers, and scientists working in the field of agricultural biotechnology, microbiology, mycology and plant pathology, and allied fields of plant and microbial sciences. The book in this context attempts to provide an integrative and exhaustive study as well as research material that would help the scientific community in wide respect. .
    Type of Medium: Online Resource
    Pages: XVIII, 582 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819900305
    Series Statement: Rhizosphere Biology,
    DDC: 630
    Language: English
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  • 168
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Nutrition   . ; Medical microbiology. ; Human physiology. ; Medicine, Preventive. ; Health promotion. ; Nutrition. ; Medical Microbiology. ; Human Physiology. ; Health Promotion and Disease Prevention.
    Description / Table of Contents: Chapter 1. Physiological and Metabolic Functions of the Intestinal Epithelium: From the Small to the Large Intestine -- Chapter 2. Intestine Offers Board and Lodging for Intestinal Microbes on a Short- or Long-Term Stay -- Chapter 3. Metabolism of Dietary Substrates by Intestinal Bacteria and Consequences for the Host Intestine -- Chapter 4. Alimentation, Bacterial Metabolites, and Host Intestinal Epithelium -- Chapter 5. Modification of the Bacterial Metabolites by the Host after Absorption, and Consequences for the Peripheral Tissues’ Metabolism, Physiology, and Pathophysiology -- Chapter 6. Lessons to Be Learned from Clinical and Experimental Research on the Intestinal Microbiota Metabolic Activity for Health Benefit and Perspectives.
    Abstract: This book provides an overview of the metabolism of dietary compounds by the intestinal microbiota, and on the consequences of such metabolic activity on host metabolism and physiological functions; both in intestinal and peripheral tissues. Over the last years, our understanding of the causal links between microbiota metabolic activity towards dietary and endogenous substrates and human health status has evolved extensively. In this context, the book starts with a comprehensive introduction devoted to the physiological and metabolic functions of the intestinal epithelium, followed by a part dedicated to the way intestine offers board and lodging for microbes being on a short- or long-term stay. The next chapters focus on the utilization of the available substrates from diet by the intestinal bacteria to produce numerous bacterial metabolites, and on the impact of such microbial activity, in the first place for communication between microbes, and for communication between microbes and lodging host. As will be detailed, this latter process of interkingdom communication leads to either beneficial or deleterious effects on intestinal physiology and metabolism. Special attention is given to selected pathophysiological processes namely chronic intestinal inflammation, colorectal carcinogenesis, and diarrhea. Then, the effects of modifications of bacterial metabolites and other bioactive compounds by the host after intestinal absorption, and consequences for peripheral tissue functions are presented. Summarizing the state of the art on what is known about the metabolic crosstalk between gut microbiota and human metabolism, as well as perspectives for further experimental and clinical research, this book provides a useful resource for researchers, professionals, and students with a background in biology, and/or nutrition, medicine, pharmacology, and for those which are involved in the agriculture and food production. By explaining technical terms all along the text, this book should be understandable also for interested non-specialists.
    Type of Medium: Online Resource
    Pages: XIII, 254 p. 57 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031263224
    DDC: 613.2
    Language: English
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  • 169
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Ecology . ; Environmental sciences Mathematics. ; Environment. ; Conservation biology. ; Statistics . ; Ecology. ; Mathematical Applications in Environmental Science. ; Environmental Sciences. ; Conservation Biology. ; Statistics.
    Description / Table of Contents: 0. Introduction - Ecologist in Wonderland -- Part 1. Linking Ecotoxicology and Ecology -- Chapter 1. Basic Concepts of Ecological Risk Assessment -- Chapter 2. Population-level assessment -- Chapter 3. Population models of extinction -- Chapter 4. Population level assessment using the canonical model -- Part 2. Models for ecotoxicology -- Chapter 5. Species Sensitivity Distribution in Ecological Risk Assessment -- Chapter 6. BLM: A model for predicting metal toxicities -- Chapter 7.Mathematical models for chemical mixtures -- Chapter 8.Statistics and related topics.
    Abstract: This book introduces various mathematical models used in ecological risk assessment, primarily discussing models used in hazard assessment. The book aims to link ecology and conservation biology with risk assessments, bringing together the knowledge of ecotoxicology and ecology for effective risk assessment. The first part describes population-level assessment in ecological risk assessment. The chapters cover current methodologies for ecological risk assessment, individual-level assessment, population dynamics models for population-level assessment, case studies, mathematical models for population extinctions, the derivation of mean time to extinction (MTE) and their case studies. The second part of the book discusses the mathematical models involved in hazard assessments. It introduces the method of risk assessment using species sensitivity distributions (SSDs), hazard assessment of metals, chemical mixtures using the Michaelis-Menten equation, basic elements of statistics and related topics. Expected readers are risk assessors in governments and public sectors, students and young researchers interested in environmental science. The book is made accessible and easy to follow by beginners in mathematical biology and theoretical ecology.
    Type of Medium: Online Resource
    Pages: XIV, 202 p. 90 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789819903092
    Series Statement: Theoretical Biology,
    DDC: 577
    Language: English
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  • 170
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Regenerative medicine. ; Biomedical engineering. ; Cytology. ; Biomaterials. ; Cells. ; Biotechnology. ; Regenerative Medicine and Tissue Engineering. ; Biomedical Engineering and Bioengineering. ; Cell Biology. ; Biomaterials-Cells. ; Biotechnology. ; Biomaterials.
    Abstract: Cutting-edge engineering approaches towards modelling lung homeostasis and disease have created dynamic new opportunities for interdisciplinary collaboration and unprecedented progress toward understanding and treating lung disease. This text connects established research in lung biology and physiology to innovative engineering strategies for pulmonary modelling. This unique approach aims to encourage and facilitate progress among a greater audience of basic and translational scientists, clinicians, and medical practitioners. Engineering Translational Models of Lung Homeostasis and Disease illustrates the advances in lung tissue characterization, revealing dynamic changes in the structure, mechanics, and composition of the extracellular matrix. This information paves the way for tissue-informed engineering models of pulmonary tissue, improved design of clinical materials, and advances against a variety of common pathologies. Current translational challenges are highlighted, as are engineering opportunities to overcome these barriers. This foundational text holds valuable lessons for researchers and clinicians throughout the fields of engineering, materials science, cell biology, pulmonary medicine, and clinical science. Chapter 4 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
    Type of Medium: Online Resource
    Pages: X, 326 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031266256
    Series Statement: Advances in Experimental Medicine and Biology, 1413
    DDC: 612.028
    Language: English
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  • 171
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Geriatrics. ; Geriatric nursing. ; Cardiology. ; Epidemiology. ; Geriatrics. ; Geriatric Care. ; Cardiology. ; Epidemiology.
    Description / Table of Contents: Preface -- Frailty: what is it?- Tools for assessing frailty in older people: general concepts -- Epidemiology of frailty in older people -- Epidemiology of cardiovascular diseases in the elderly -- The impact of frailty on the role of the classical cardiovascular risk factors -- Frailty as cardiovascular risk factor (and vice versa) -- Inflammation, frailty and cardiovascular disease -- Oxidative stress, frailty and cardiovascular disease: current evidence -- The importance of cellular senescence in frailty and cardiovascular diseases -- Comprehensive geriatric assessment in cardiovascular disease -- Frailty in cardiac surgery -- Physical exercise for frailty and cardiovascular disease -- Cardiac rehabilitation for frail older people -- Future perspectives.
    Abstract: This book aims to clarify the potential association between frailty and cardiovascular disease in older people. Covering the biological as well as the clinical point of view, it allows researchers and clinicians to discover the significance of this topic. The contributions cover the most important aspects in the potential relationship between frailty and cardiovascular disease. In particular, authoritative authors in this field have clarified the definition and the epidemiology of frailty and cardiovascular disease in older people. A large part of the volume is dedicated to the biological mechanisms of frailty and cardiovascular disease, trying to find those in common between these two conditions. Since this book is dedicated to both researchers and clinicians, we have proposed some chapters to the importance of comprehensive geriatric assessment in the evaluation and treatment of cardiovascular diseases and frailty. In this regard, the importance of geriatric evaluation in cardiac surgery for older people is well covered. Finally, the importance of cardiac rehabilitation and physical exercise is summarized, being, actually, the most important treatments for both frailty and cardiovascular disease. Written by many well-known and widely published experts in their respective fields, this book will appeal to a wide readership such as researchers in the field and clinicians, especially suited in geriatric medicine and cardiology who, every day, face frail older patients. .
    Type of Medium: Online Resource
    Pages: VIII, 154 p. 7 illus., 4 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030333300
    Series Statement: Advances in Experimental Medicine and Biology, 1216
    DDC: 618.97
    Language: English
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  • 172
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Immunology. ; Virology. ; Pharmacology. ; Human physiology. ; Immunology. ; Virology. ; Pharmacology. ; Human Physiology.
    Description / Table of Contents: Chapter 1. Significance and dynamics of immune responses during viral pathogenesis -- Chapter 2. Antibody-dependent enhancement of viral infections -- Chapter 3. Inflammation during virus infection: swings and roundabouts -- Chapter 4. Interferons and their role in Viral infection -- Chapter 5. Role of Cytokines in combating viral infections: Siginificance and relevance -- Chapter 6. B cells and their role in combating viral diseases -- Chapter 7. Significant role of Cellular activation in viral infections Bojjibabu Chidipi1 Samuel Ignatious Bolleddu,Ganugula Mohana Sheela and Alavala Mattareddy -- Chapter 8. Macrophages/Micro vesicles and their task in viral diseases Macrophages/Microvesicles and their task in viral diseases -- Chapter 9. T cells in viral infections: The myriad flavours of antiviral immunity -- Chapter 10. Potentiality of Toll Like Receptors (TLRs) in viral infections -- Chapter 11. Activation and immune evasion of viruses from Complement system -- Chapter 12. microRNAs and their role in viral infection -- Chapter 13. Evolution, Distribution and Diversity of Immunodeficiency Viruses -- Chapter 14. Role of immune cells in Hepatitis B infection -- Chapter 15. Role of RNA Sensors in Immunity against Viral Diseases -- Chapter 16. Role of DNA Sensors in Immunity against Viral Diseases -- Chapter 17. Advanced immunotechnological methods for detection and diagnosis of viral infections: Current applications and future challenges -- Chapter 18. Current advances in viral vaccines development and Research. .
    Abstract: This book discusses various components of the innate and adaptive immune response in combating viral infections, presenting the recent advances in our understanding of innate immunity recognition of viruses and highlighting the important role of inflammation, cytokines such as interferon, toll-like receptors and leukocytes in the initial detection of invading viruses and subsequent activation of adaptive immunity. It also summarizes the role of the adaptive immunity against viral infections through clearance of virus and establishment of memory response that protects against the recurrent infections. In addition, the book examines the role of DNA and RNA sensors in viral recognition and in controlling viral infection. Lastly, it reviews the latest developments in the development of the rational viral vaccines. As such it is a useful resource book for postgraduate and early researchers wanting to gain insights into the immune response to viral infections.
    Type of Medium: Online Resource
    Pages: XXIII, 283 p. 27 illus., 26 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811510458
    DDC: 571.96
    Language: English
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  • 173
    Keywords: Medicine Research. ; Biology Research. ; Microbial ecology. ; Biotic communities. ; Agriculture. ; Industrial microbiology. ; Biomedical Research. ; Microbial Ecology. ; Ecosystems. ; Agriculture. ; Industrial Microbiology.
    Abstract: The book explores the challenges and opportunities associated with high-altitude agro-ecosystems and the factors that influence them. It discusses the various indigenous agricultural practices and approaches, as well as the microbiology of mountain & hill agro-ecosystems, providing a comprehensive overview of the various factors that control the microbiome at high altitudes. The contributions examine microbiological advances, such as use of “omics” technologies for hill agriculture and environmental sustainability, and explore the use of nanotechnology for agricultural and environmental sustainability at higher altitudes. The book also describes various aspects of low-temperature microbiology in the context of high-altitude farming and environmental sustainability.
    Type of Medium: Online Resource
    Pages: XIII, 491 p. 62 illus., 49 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811519024
    Series Statement: Rhizosphere Biology,
    DDC: 610.72
    Language: English
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  • 174
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Cancer. ; Stem cells. ; Regenerative medicine. ; Cancer Biology. ; Stem Cell Biology. ; Regenerative Medicine and Tissue Engineering.
    Description / Table of Contents: The tumor microenvironment: focus on extracellular matrix -- Keratan Sulphate in the Tumour Environment -- Hyaluronan in the tumor microenvironment -- Fibronectin in the tumor microenvironment -- Matrix metalloproteinases role in tumor microenvironment -- Flipping the Molecular Switch: Influence of Perlecan and its Modifiers in the Tumor Microenvironment -- Heparan sulfate in the tumor microenvironment -- The role of Glypican-1 in the tumour microenvironment -- Index.
    Abstract: Revealing essential roles of the tumor microenvironment in cancer progression, this volume focuses on the extracellular matrix components with the tumor during cancer development. Further, it teaches readers about the roles of distinct constituents of the tumor microenvironment and how they affect cancer development. Topics include heparan sulphate, hyaluronan, fibronectin, perlecan, glypican, matrix metalloproteinases, and much more. Taken alongside its companion volumes, Tumor Microenvironment: Extracellular Matrix Components – Part A updates us on what we know about the different aspects of the tumor microenvironment, as well as apprises us on the future advances in the field. For the newer generation of researchers, this volume serves as a useful introduction to the history of scientists’ focus on the tumor microenvironment, and explores how this knowledge is currently applied in cancer treatments. The book will be an essential text for advanced cell biology and cancer biology students, as well as for scientists seeking an update on the developments in tumor microenvironment research. All of the chapter authors are renowned international experts in the field of cancer biology, and in the specific subfields that are the focus of their chapters.
    Type of Medium: Online Resource
    Pages: XI, 181 p. 29 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030401467
    Series Statement: Advances in Experimental Medicine and Biology, 1245
    DDC: 571.978
    Language: English
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  • 175
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    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Human physiology. ; Sports sciences. ; Medicine, Preventive. ; Health promotion. ; Human Physiology. ; Sport Science. ; Health Promotion and Disease Prevention.
    Description / Table of Contents: Chapter 1. An overview of the beneficial effects of exercise on health and performance -- Chapter 2. Type of exercise training and training methods -- Chapter 3. Molecular mechanisms mediating adaptation to exercise -- Chapter 4. Exercise and organ crosstalk -- Chapter 5. Exercise and Hyperlipidemia -- Chapter 6. Exercise and Type 2 diabetes -- Chapter 7. Exercise and Type 1 Diabetes -- Chapter 8. Exercise and Polycystic ovarian syndrome -- Chapter 9. Exercise and insulin resistance -- Chapter 10. Exercise and Hypertension -- Chapter 11. Exercise and Coronary heart disease -- Chapter 12. Exercise and Peripheral Arteriosclerosis -- Chapter 13. Exercise and Stroke -- Chapter 14. Exercise and cardiovascular protection -- Chapter 15. Exercise and Osteoarthritis -- Chapter 16. Exercise and Chronic Pain -- Chapter 17. Exercise and muscle atrophy -- Chapter 18. Exercise and Depressive disorder -- Chapter 19. Exercise and Parkinson’s disease -- Chapter 20. Exercise and Dementia -- Chapter 21. Exercise and Schizophrenia -- Chapter 22. Exercise and Multiple Sclerosis -- Chapter 23. Exercise and anxiety -- Chapter 24. Exercise and Chronic obstructive pulmonary disease (COPD) -- Chapter 25. Exercise and Asthma -- Chapter 26. Exercise and Cystic fibrosis -- Chapter 27. Exercise regulates the immune system -- Chapter 28. Effects of Exercise on the immune function, quality of life and mental health in HIV/AIDS individuals -- Chapter 29. Effects of Exercise on Memory Interference in Neuropsychiatric Disorders -- Chapter 30. Effects of Exercise on Long-Term Potentiation in Neuropsychiatric Disorders -- Chapter 31. Prospective advances in beneficial effects of exercise on human health.
    Abstract: This book shares the latest findings on exercise and its benefits in preventing and ameliorating numerous diseases that are of worldwide concern. Addressing the role of exercise training as an effective method for the prevention and treatment of various disease, the book is divided into eleven parts: 1) An Overview of the Beneficial Effects of Exercise on Health and Performance, 2) The Physiological Responses to Exercise, 3) Exercise and Metabolic Diseases, 4) Exercise and Cardiovascular Diseases, 5) Exercise and Musculoskeletal Diseases, 6) Exercise and Neurological and Psychiatric Diseases, 7) Exercise and the Respiration System, 8) Exercise and Immunity, 9) Exercise and HIV/AIDS, 10) Exercise and Neuropsychiatric Disorders, and 11) Future Prospects. Given its scope, the book will be particularly useful for researchers and students in the fields of physical therapy, physiology, medicine, genetics and cell biology, as well as researchers and physicians with a range of medical specialties.
    Type of Medium: Online Resource
    Pages: IX, 459 p. 12 illus., 9 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811517921
    Series Statement: Advances in Experimental Medicine and Biology, 1228
    DDC: 612
    Language: English
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  • 176
    Keywords: Plant physiology. ; Botanical chemistry. ; Plants Development. ; Agriculture. ; Plant Physiology. ; Plant Biochemistry. ; Plant Development. ; Agriculture.
    Description / Table of Contents: Chapter 1: Reproductive Ecology of Flowering Plants: An Introduction -- Chapter 2: Climate Change and Vegetation Phenology -- Chapter 3: The Pistil: Structure in Relation to its Function -- Chapter 4: Pollen-Pistil Interaction and Fertilization -- Chapter 5: Olfactory Cues as Functional Traits in Plant Reproduction -- Chapter 6: A Snapshot of Evolutionary History of Floral Nectaries across Angiosperm Lineages -- Chapter 7: Floral Symmetry – What it is, How it Forms, and Why it Varies -- Chapter 8: Resource Allocation in Flowering Plants: Concept and Implications -- Chapter 9: Dynamics of Eco-evolutionary Forces in Shaping Dioecy -- Chapter 10: Secondary Pollen Presentation in Flowering Plants -- Chapter 11: Outbreeding in Angiosperms: Floral Architecture and Sexuality -- Chapter 12: Sexual Selection in Angiosperms: Paradox Re-visited -- Chapter 13: Role of Apomixis in Perpetuation of Flowering Plants: Ecological Perspective -- Chapter 14: Biotic Seed Dispersal Mechanisms Of Tropical Rain Forests – Bats, Fishes And Migratory Birds -- Chapter 15: (Trans)gene Flow: Mechanisms, Biosafety Concerns and Mitigation for Containment -- Chapter 16: ‘Global Pollinator Crisis’ and its Impact on Crop Productivity and Sustenance of Plant Diversity.
    Abstract: Sexual reproduction is the predominant mode of perpetuation for flowering plant species. Investigating the reproductive strategies of plants has grown to become a vast area of research and, in crop plants, covers events from flowering to fruit and seed development; in wild species, it extends up to seed dispersal and seedling recruitment. Thus, reproduction determines the extent of yield in crop plants and, in wild plants, also determines the efficacy of recruiting new adults to the population, making this field important both from fundamental and applied plant biology perspectives. Moreover, in light of the growing concerns regarding food and nutritional security for the growing population and preserving biological diversity, reproductive biology of flowering plants has acquired special significance. Extensive studies on various facets of reproduction are being carried out around the world. However, these studies are scattered across research journals and reviews from diverse areas of biology. The present volume covers the whole spectrum of reproductive ecology, from phenology and floral biology, to sexuality and pollination biology/ecology including floral rewards, breeding systems, apomixis and seed dispersal. In turn, transgene flow, its biosafety and mitigation approaches, and the ‘global pollinator crisis’, which has become a major international concern in light of the urgent need to sustain crop yield and biodiversity, are discussed in detail. Given its scope, the book offers a valuable resource for students, teachers and researchers of botany, zoology, ecology, agriculture and forestry, as well as conservation biologists.
    Type of Medium: Online Resource
    Pages: XVII, 413 p. 38 illus., 24 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811542107
    DDC: 571.2
    Language: English
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  • 177
    Keywords: Agriculture. ; Cytology. ; Stress (Physiology). ; Genetics. ; Plant biotechnology. ; Plant physiology. ; Agriculture. ; Cellular Stress. ; Genetics and Genomics. ; Plant Biotechnology. ; Plant Physiology.
    Description / Table of Contents: Chapter 1. Origin and Evolution of Rice as Domesticated Food Crop -- Chapter 2. Major constraints for global rice production: Changing climate, abiotic and biotic stresses -- Chapter 3. Germplasm and genetic diversity studies in rice for stress response and quality traits -- Chapter 4. Potentiality of wild rice in quality improvement of cultivated rice varieties -- Chapter 5. Improvement of Rice Quality: The New Revolution -- Chapter 6. Sequencing the Rice Genome: Gateway to Agricultural Development -- Chapter 7. Genomics approaches to understand varietal differences in rice species and genotypes with respect to stress response and quality traits -- Chapter 8. Selection and hybridization techniques for stress management and quality improvement in rice -- Chapter 9. Transformation techniques and molecular analysis of transgenic rice -- Chapter 10. New approaches for improving salt stress tolerance in rice -- Chapter 11. Genomics and biotechnological approaches in generating salinity and drought tolerance in rice -- Chapter 12. An integrated approach for drought tolerance improvement in rice -- Chapter 13. Genomics and genetic engineering to develop metal/metalloid stress tolerant rice -- Chapter 14. Potential biotechnological strategies to improve quality and productivity of rice under arsenic stress -- Chapter 15. Genetic engineering: A powerful tool to abrogate the effect of metal/metalloid toxicity in rice -- Chapter 16. Genomics and genetic engineering of rice for tolerance to ozone and anoxia -- Chapter 17. Physiological and genetic basis of submergence tolerance in rice -- Chapter 18. Transgenic rice for survival in nutrient-deficient soil -- Chapter 19. Genetic engineering in rice to survive in nutrient-deficient soil -- Chapter 20. Developing C4 rice for higher photosynthetic efficiency and environmental stress tolerance -- Chapter 21. Rice tolerance to high light intensity and UV radiation: Genomics, breeding and genetic engineering -- Chapter 22. Improving rice tolerance to low and high temperature stress through biotechnological approaches -- Chapter 23. Biotechnological approaches to develop rice tolerance to low and high temperature stress -- Chapter 24. Influence of night temperature on rice yield and quality -- Chapter 25. Rice tolerance to multiple abiotic stress: Genomics and genetic engineering -- Chapter 26. Targeting metabolic pathways for genetic engineering abiotic stress tolerance in rice -- Chapter 27. Targeting phytohormone levels for genetic engineering abiotic stress tolerance in rice -- Chapter 28. The effect of exposure to a combination of stressors on rice productivity and grain yields -- Chapter 29. Rice Grain Quality Traits: Neglected or Less Addressed? -- Chapter 30. Rice grain quality and abiotic stress: Genomics and biotechnological perspectives -- Chapter 31. Increasing rice grain yield under abiotic stresses: mutagenesis, genomics and transgenic approaches.-.
    Abstract: This book focuses on the conventional breeding approach, and on the latest high-throughput genomics tools and genetic engineering / biotechnological interventions used to improve rice quality. It is the first book to exclusively focus on rice as a major food crop and the application of genomics and genetic engineering approaches to achieve enhanced rice quality in terms of tolerance to various abiotic stresses, resistance to biotic stresses, herbicide resistance, nutritional value, photosynthetic performance, nitrogen use efficiency, and grain yield. The range of topics is quite broad and exhaustive, making the book an essential reference guide for researchers and scientists around the globe who are working in the field of rice genomics and biotechnology. In addition, it provides a road map for rice quality improvement that plant breeders and agriculturists can actively consult to achieve better crop production.
    Type of Medium: Online Resource
    Pages: XVII, 777 p. 75 illus., 48 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811541209
    DDC: 630
    Language: English
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  • 178
    Keywords: Zoology. ; Environment. ; Bioinformatics. ; Ecology . ; Biodiversity. ; Physical geography. ; Zoology. ; Environmental Sciences. ; Computational and Systems Biology. ; Ecology. ; Biodiversity. ; Earth System Sciences.
    Description / Table of Contents: Introduction -- Historical review of research on Arctic and Subarctic Aleocharinae -- Material and methods -- Impact of climate change on northern fauna and flora -- Aleocharinae as indicators of change -- Faunal analysis and discussion -- Key to tribes occurring in Arctic and Subarctic zones -- Tribe Gymnusini Heer, 1839 -- Tribe Aleocharini Fleming, 1821 -- Tribe Oxypodini C.G. Thomson, 1859 -- Tribe Tachyusini C.G. Thomson, 1859 -- Tribe Hypocyphtini Laporte, 1835 -- Tribe Myllaenini Ganglbauer, 1895 -- Tribe Liparocephalini Fenyes, 1918 -- Tribe Homalotini Heer, 1839 -- Tribe Placusini Mulsant and Rey, 1871 -- Tribe Athetini Casey, 1910 -- Tribe Falagriini Mulsant and Rey, 1873.
    Abstract: Arctic and Subarctic North America is particularly affected by climate change, where average temperatures are rising three times faster than the global average. Documenting the changing climate/environment of the north requires a structured knowledge of indicator taxa that reflect the effects of climate changes. Aleocharine beetles are a dominant group of forest insects, which are being used in many projects as indicators of environmental change. Many species are forest specialists restricted to certain microhabitats, some are generalists and others are open habitat specialists. They represent many ecological niches and, as such, are good indicators for many other species as well. The majority of Canadian aleocharine beetle species (about 600 spp.) has been studied and published by Jan Klimaszewski et al. (2018, 2020), mainly from southern, central, and western Canada, while the northern taxa remain poorly known and documented. The aim of the present book is to summarize the knowledge on this insect group in the Arctic and Subarctic North America and to provide a diagnostic and ecological tool for scientists studying and monitoring insects in northern Canada and Alaska. The book includes a review of the literature, information on 238 species and their habitats, taxonomic review, images, and identification tools.
    Type of Medium: Online Resource
    Pages: XIV, 712 p. 315 illus., 307 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030681913
    DDC: 590
    Language: English
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  • 179
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Reproductive health. ; Cytology. ; Biomedical Research. ; Reproductive Medicine. ; Cell Biology.
    Description / Table of Contents: Ch 1: The seminiferous epithelial cycle of spermatogenesis: Role of non-receptor protein kinases -- Ch 2: Sertoli cells: immunology and spermatogenesis -- Ch 3: Innate immunity and spermatogenesis -- Ch 4: Cell apoptosis and spermatogenesis -- Ch 5: Transcriptional regulation of spermatogenesis -- Ch 6: Sertoli cell cytoskeleton and spermatogenesis -- Ch 7: Leydig cell and spermatogenesis -- Ch 8: Cross-talk of cell junctions to support spermatogenesis -- Ch 9: Coordination of F-actin- and MT-based cytoskeletons to support spermatogenesis -- Ch 10: Regulation of the blood-testis barrier by basement membrane laminin-α2 chain -- Ch 11: Regulation of spermatogenesis by collagens -- Ch 12: Androgen regulation of spermatogenesis -- Ch 13: Use of molecular modeling to study spermatogenesis -- Ch 14: Acrosome biogenesis during spermatogenesis -- Ch 15: Stem cells and spermatogenesis -- Ch 16: Advances in our understanding of spermatogenesis in humans -- Ch 17: Leydig cell function in aging men -- Ch 18: Regulation of human spermatogenesis.
    Abstract: This new edition provides an update on the molecular mechanisms that regulate spermatogenesis. In addition to the rodent as a study model, chapters also include research on studies in humans. It includes the latest approaches of studying spermatogenesis, such as the use of bioinformatics, molecular modeling and others which are not commonly found in published materials. It also reviews the latest developments in the field, such as studies on the role of regulatory RNAs on spermatogenesis. Due to the declining fertility rate among men, a brand new chapter highlights the impact of environmental toxicants on spermatogenesis.
    Type of Medium: Online Resource
    Pages: X, 319 p. 44 illus., 40 illus. in color. , online resource.
    Edition: 2nd ed. 2021.
    ISBN: 9783030777791
    Series Statement: Advances in Experimental Medicine and Biology, 1381
    DDC: 610.72
    Language: English
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  • 180
    Keywords: Botany. ; Plant biotechnology. ; Plant cells and tissues. ; Plant Science. ; Plant Biotechnology. ; Plant Cell Biology.
    Description / Table of Contents: Bamboo: origin, habitat, distributions and global prospective -- Molecular markers in bamboos: understanding reproductive biology, genetic structure, interspecies diversity and clonal fidelity for conservation and breeding -- Standard protocols for in vitro propagation of bamboo with emphasis on axillary shoot proliferation -- Somatic embryogenesis in bamboos: advances and prospects -- Initiation and establishment of cell suspension culture in bamboo -- Micro-morpho-anatomical alterations in micropropagated plants of endrocalamus strictus -- Micropropagation of bamboos and clonal fidelity assessment using molecular markers -- Standardization of laboratory to land transfer strategies of micropropagated plantlets of bamboo -- Management of bamboo genetic resources and clonal production systems -- Polymorphism and phylogenetic relationships in bamboo -- Transgenics approaches in Bamboo -- Advances in Conservation of Bamboo Genetic Resources through Whole Seeds Cryopreservation -- Application of Biotechnological Tool in Bamboo Improvement -- Ethnobamboology: traditional uses of bamboos and opportunities to exploit genomic resources for better exploitation -- Bamboo flowering in South America: what the past tells about the future -- Molecular Markers in Bamboo Genotyping: Prospects for Conservation and Breeding -- Application of bamboo in the food and pharmaceutical industry -- Functional pasta: a comparative study of the use of bamboo shoot fiber and white fibers -- Bamboo fiber as a substitute for fat and/or sugar in cookies -- Practical application of bamboo as a building material: trends and challenges.
    Abstract: “Green gold” or “Poor Man’s Timber” are commonly used terms for bamboo that is a valuable and renewable resource of the world, and has always been an elemental part of human beings in terms of social and economic value. Bamboo is considered a multipurpose plant and has a prolonged history as an adaptable and extensively used renewable resource in conventional and commercial applications. Therefore, the annual demands for bamboos have already out-crossed the annual yields across the world. And the current scenario has forced scientists to pay more attention to the utilization of biotechnological tools for better understanding and improving bamboos. The book provides an overview of the different biotechnological approaches to advance bamboo research and better utilization of bamboo resources for human beings. Various applications of biological techniques in relation to bamboo have been discussed in details, for example, plant tissue culture techniques, somatic embryogenesis, germplasm conservation techniques, use of the molecular markers, transcriptomics, polymorphism, and phylogenetic relations in bamboo. It also addresses the novel industrial applications of bamboo in structural, food, and pharmaceuticals along with traditional uses. The aggregated information in this book demonstrates the way for the improved and sustainable practice of bamboos to fulfill the future needs of the world. This book is intended for use in both the industry and academia.
    Type of Medium: Online Resource
    Pages: XV, 481 p. 82 illus., 72 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9789811613104
    DDC: 580
    Language: English
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  • 181
    Keywords: Food science. ; Food Analysis. ; Chemistry. ; Nutrition   . ; Food Safety measures. ; Food Science. ; Food Chemistry. ; Nutrition. ; Food Safety.
    Description / Table of Contents: Chapter 1 Introduction -- Chapter 2.Global Scenario of Coconut and Coconut Water -- Chapter 3 Tender Coconut Varieties -- 4 Composition, Properties and Reactions of Coconut Water -- Chapter 5 Processing of Coconut Water -- Chapter 6 Packing, Storage and Transport of Coconut Water -- Chapter 7 Standards of Coconut Water -- Chapter 8 Value addition in Coconut Water -- Chapter 9 Health Benefits of Coconut Water -- Chapter 10 Contamination and Adulteration of Coconut Water -- Chapter 11 Patents Granted on Coconut Water -- Chapter 12 Coconut Water- The Way Forward.
    Abstract: Coconut water, a naturally-canned tropical beverage, has been gaining popularity in recent years and has drawn the attention world over as a natural and nutritional wellness beverage. The research published thus far on coconut water has mainly focused on its specific uses, biochemical composition and health benefits as well as processing and preservation techniques and has been published mostly in journal articles. Only a few books covering a wide spectrum of coconut water for health and wellness are currently available. This work offers a comprehensive and fully updated overview of coconut water from processing techniques to value addition to safety to nutritional benefits and beyond. Coconut Water: Processing, Distribution & Nutritional Benefits provides in-depth details on all of the major processing techniques required to produce and maintain a quality product free of contamination and adulteration. The book covers the standards of coconut water production and distribution in various countries enabling the processors and exporters to manufacture and export for better revenue realization. The book also provides details of patents related to coconut water granted to researchers. Another important aspect of this work is comprehensive coverage on the various nutritional and health benefits of coconut water consumption as well as on the value addition (traditional and innovative products). In markets across the world, consumers of all ages have been turning to coconut water for its taste and nutritional benefits. This book will provide researchers, processors and exporters the comprehensive information needed to produce and market quality, nutritional coconut water for consumers. .
    Type of Medium: Online Resource
    Pages: XXXV, 507 p. 57 illus., 56 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031107139
    DDC: 641.3
    Language: English
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  • 182
    Keywords: Medical sciences. ; Ethics. ; Medical education. ; Social sciences. ; Humanities. ; Health Sciences. ; Moral Philosophy and Applied Ethics. ; Medical Education. ; Humanities and Social Sciences.
    Description / Table of Contents: Part 1: Defining Medical Professionalism -- Chapter 1. Professionalism and Medical Practice – Introduction (Luis Vivanco) -- Chapter 2. Medical Professionalism – A Developmental View from the Trenches (Renzo Pegoraro) -- Chapter 3. The Need for a Common Set of Competencies as Ingredients for Medical Professionalism, Paired with a Common Program of Assessment (Aaron R. Douglas) -- Part 2: Medical Professionalism from Broader Perspectives -- Chapter 4. Medical Professionalism – legal framework (Sunčana Roksandić) -- Chapter 5. Medical Professionalism – Sociological Framework (Gordana Cerjan Letica) -- Part 3: The Moral Foundations of Medical Professionalism -- Chapter 6. Medical Professionalism – Philosophical Framework (Marko Ćurković) -- Chapter 7. Medical Professionalism from Virtue Ethics Perspective (Claudia Ruiz Sotomayor) -- Part 4. Medical Professionalism – Interpersonal Views and Considerations -- Chapter 8. Interpersonal or Relational Professionalism (Marko Ćurković) -- Chapter 9. The Physician Patient Relationship: a Philosophical Perspective on Medical Professionalism and Virtues (Roberto Dell’Oro) -- Chapter 10. Physicians Towards Fellow Colleagues (Marko Ćurković) -- Chapter 11. Physicians Towards Other Healthcare Professionals (and Vice Versa) (Marko Ćurković) -- Chapter 12. Interdisciplinary Challenges to Interprofessional Practice (Jos V. M. Welie) -- Part 5. Medical Professionalism – Unique Challenges and Duties -- Chapter 13. The Impact of Uncertainties on Physicians’ Health and Wellbeing (Marko Ćurković) -- Chapter 14. Physicians and Organization: For a Reflective Organizational Professionalism (Jean-Philippe Cobbaut) -- Chapter 15. Victims or Actors? Can Professionalism Shape Physicians’ Roles Inside the Health Care System? (Bernice Elger) -- Chapter 16. What do Doctors and Society Owe Each Other? A Scanlonian Reflection on Medical Professionalism (Andrew Papanikitas) -- Chapter 17. Physicians Towards Society (and Vice Versa) (Sabine Salloch) -- Part 6: Medical Professionalism Across Contemporary and Cultural Landscapes -- Chapter 18. Professionalism and Medical Practice - Cultural Perspectives (Marko Ćurković) -- Chapter 19. Physicians as Citizens of the World (Henk ten Have) -- Chapter 20. Physicians as Agents in Evolving Knowledge Landscapes (Srećko Gajović) -- Chapter 21. Afterthoughts: Towards a Realpolitik of Professionalism (Nathan Emmerich).
    Abstract: This book provides insights into dynamic and complex interrelationships between professionalism and medical practice. It does so by looking into the most relevant and recent theoretical and practical frameworks and by systematizing and integrating extensive and growing literature on medical professionalism. Through honest and prudent contributions from very diverse backgrounds and contexts, this book provides an understanding of medical professionalism derived from a broader historical and cultural context in order to contribute to everyday professional life and practice – the very place of its existence. The book presents the conflicting and sometimes irreconcilable demands and challenges physicians face in everyday practice. A better understanding of these fundamental issues is the only way for medicine to maintain and preserve its unique morality, the same one that enabled its existence in the first place. The book is relevant for everyone immersed and interested in the subject of medical professionalism as a resource, which may ease or guide them through the complexities of issues at hand. It will also contribute to the ongoing debate on medical professionalism, medical ethics, bioethics, and professionalism and ethics in general.
    Type of Medium: Online Resource
    Pages: XXI, 493 p. 59 illus., 51 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031097331
    Series Statement: The International Library of Bioethics, 98
    DDC: 610
    Language: English
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  • 183
    Keywords: Biomaterials. ; Nanotechnology. ; Biomedical engineering. ; Polymers. ; Microfluidics. ; Biomaterials. ; Nanotechnology. ; Biomedical Engineering and Bioengineering. ; Biomedical Materials. ; Polymers. ; Microfluidics.
    Description / Table of Contents: Introduction to high resolution manufacturing from 2D to 3D/4D printing -- Technologies evolutions and Design Considerations -- Vat photopolymerization -- Stereolithography -- Digital Light Processing -- Continuous liquid interface production -- Materials -- Multi-photon polymerization -- 2PP -- Materials -- Powder bed fusion -- Selective Laser Sintering -- Materials -- Commodity Polymers -- Engineering Polymers -- High-Performance Polymers -- Thermoplastic Elastomers -- The role of fillers -- Ink-jet printing -- Polyjet printing -- Aerosol jet printing -- Materials -- Volumetric 3D printing -- Computed Axial Lithography -- Xolography -- Materials -- Impact on different research fields and case studies -- Biomedical applications -- Cells culture, Microfluidics, rapid diagnostic tools -- Electronic applications -- Sensors and biosensors, actuators, integrated circuits -- Energy applications -- Supercapacitors, Energy harvesting -- Photonic applications -- Woodpile structures, light guides, optical fiber -- Future outlook.
    Abstract: This book provides a comprehensive presentation of the most frequently used high resolution manufacturing techniques available, as well as the polymeric materials used for each of the techniques. Divided into two parts covering the technologies and materials used and the impact on different research fields and case studies, High Resolution Manufacturing from 2D to 3D/4D Printing: Applications in Engineering and Medicine addresses issues like throughput improvement by volumetric 3D printing and presenting novel applications and case studies. In addition, this book also covers the latest breakthrough developments and innovations to help readers understand the future applications of this technology across various disciplines, including biomedicine, electronics, energy, and photonics.
    Type of Medium: Online Resource
    Pages: X, 300 p. 128 illus., 112 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031137792
    DDC: 620.19
    Language: English
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  • 184
    Keywords: Medicine Research. ; Biology Research. ; Cardiovascular system. ; Physiology. ; Cardiology. ; Clinical biochemistry. ; Biomedical Research. ; Cardiovascular Physiology. ; Cardiology. ; Medical Biochemistry.
    Description / Table of Contents: Past, present and future perspectives of renin angiotensin system -- Biochemical pathways of renin angiotensin system -- Structure-function relationships of angiotensin II receptors -- Signal transduction mechanism of angiotensin II -- Renin angiotensin system: Pathophysiology and clinical implications in cardiovascular disease COVID-19 infection -- Angiotensin II and the pathogenesis of hypertension -- Signaling transduction of angiotensin II in hypertension -- Role of angiotensin II type 1 receptors in vascular remodeling in hypertension -- Molecular and cellular mechanisms of renin-angiotensin system in hypertension -- Tissue renin-angiotensin system and risks in hypertension -- Oxidative stress and angiotensin II-induced hypertension -- Angiotensin II: inflammatory system disorder and hypertension -- Therapeutic approaches for angiotensin receptor blockers in hypertension -- Renin-angiotensin systems: A pivotal role in the development of atherosclerosis -- Angiotensin II induced intracellular signaling pathways in pathogenesis of atherosclerosis -- Cellular and molecular mechanisms of Ang II: Contribution to atherosclerotic plaque vulnerability -- Role of angiotensin II, nitric oxide and reactive oxygen species in atherosclerosis -- The renin-angiotensin system and inflammatory processes in atherosclerotic lesion formation -- Role of renin-angiotensin system in alterations in blood lipids and gene expression in atherogenesis -- Effects of angiotensin-converting enzyme and receptors in atherosclerosis -- Effects of angiotensin II on cardiac arrhythmia and signal transduction -- Angiotensin II induced oxidative stress contribute to ventricular arrhythmias -- Modulation of renin angiotensin system: Beneficial effect on ventricular arrhythmias -- ACE inhibitor and ventricular arrhythmia in ischemic heart disease -- The renin-angiotensin system modulators and cardiac arrhythmias -- Angiotensin receptor blockers in the treatment of arrhythmias -- Angiotensin II induced cardiac hypertrophy and heart failure -- Renin-angiotensin system: Role in cardiac remodeling and subcellular defects in heart failure -- Renin-angiotensin system: Molecular and cellular mechanisms in heart failure -- Role of angiotensin II receptor mRNA expression in heart failure -- Renin angiotensin system: Mitochondrial dysfunction in the progression of heart failure -- Angiotensin II type 1 receptor: Genetic polymorphisms and heart failure -- Angiotensin converting enzyme 2 and angiotensin metabolism in heart failure -- Cellular and molecular mechanisms of renin-angiotensin system blockade in heart failure: An update -- Angiotensin II receptor antagonists: Modulation of the extracellular matrix regulatory system in heart failure.
    Abstract: This book on “Renin-Angiotensin System in Cardiovascular Disease” includes 25 chapters, which are organized in three sections, namely (i) modulatory aspects, (ii) pathophysiological aspects, and (iii) pharmacotherapeutic aspects. It includes an updated as well as comprehensive knowledge about molecular and cellular aspects for the role of the renin-angiotensin system (RAS) in the pathophysiology and therapy of cardiovascular diseases such as hypertension, atherosclerosis, ischemic heart disease, and heart failure. This book emphasizes the molecular and cellular mechanisms, signaling transduction pathways involved in the development of different cardiovascular diseases due to the prolonged activation of RAS. Furthermore, biochemical mechanisms are outlined for the inhibition of this system by the blockade of angiotensin converting enzyme as well as angiotensin II type 1 receptors in patients suffering from cardiovascular abnormalities. Since cardiovascular disease is the number one cause of death worldwide, leading to approximately 17.9 million deaths each year, there is a keen interest in understanding the pathogenesis and improving its therapy. In this regard, we can attest that this book provides ample information about essential components of RAS and their role in the development of cardiovascular disease. From the selection of recognized global experts in their area of investigation, this book can be seen to cover diverse cardiovascular aspects and molecular and cellular mechanisms of angiotensin II action for the development of different cardiovascular abnormalities. It is our contention that this book will be most suitable for promoting knowledge in the field of RAS biology and will be of great interest to health professionals involved in both experimental and clinical cardiology as well as academic investigators and cardiovascular scientists, graduate students, and fellows worldwide.
    Type of Medium: Online Resource
    Pages: XVIII, 452 p. 71 illus., 54 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031149528
    Series Statement: Advances in Biochemistry in Health and Disease, 24
    DDC: 610.72
    Language: English
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  • 185
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Biodiversity. ; Ecology . ; Forestry. ; Biodiversity. ; Ecology. ; Forestry.
    Description / Table of Contents: 1. Climbers - a general overview -- 2. Overview of the research on climbers from the past to the present: a global analysis -- 3. Ecology of Lianas: Diversity and distribution -- 4. Current status and future prospects -- 5. Taxonomic diversity of climbing flora in India – A compendium -- 6. Climber radiations in Angiosperms: How many families have climbers?
    Abstract: This book brings out the most comprehensive and up-to-date information on the taxonomy, biodiversity, and ecology of climbers in India. Climbing is one of the principal plant growth habits that have long attracted the interests of ecologists and evolutionary biologists. Climbing plants can add significantly to the species richness of many tropical forests ecosystems, yet they receive relatively lesser attention than trees in ecological studies. The difficulties in taxonomic assertions and lack of standard methodologies overlook climbers in plant inventories, resulting in the underrepresentation of climbers in regional floras. There is a growing consensus about the increasing abundance of climbers and their multifaceted role in tropical forests worldwide. Therefore, it is essential to understand the taxonomic diversity and ecology of climbers at the regional scale to substantiate our efforts towards constructing a global climber database, which serves as a reference for fundamental research in climber ecology and evolution. This book is of interest to biodiversity researchers, taxonomists, ecologists, and evolutionary biologists. Field biologists, forest managers, and naturalists will also find this a useful read.
    Type of Medium: Online Resource
    Pages: XI, 922 p. 1 illus. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9789811986451
    DDC: 333.95
    Language: English
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  • 186
    Online Resource
    Online Resource
    Cham :Springer Nature Switzerland :
    Keywords: Food science. ; Agriculture. ; Economic geography. ; Botany. ; Environmental management. ; Food Science. ; Agriculture. ; Economic Geography. ; Plant Science. ; Environmental Management.
    Description / Table of Contents: Chapter 1: Saffron and Tulasi -- Chapter 2: Aniseed, Shallot and Caraway -- Chapter 3: European Fill and Indian Dill -- Chapter 4: Poppy Seed.-Chapter 5: Star Anise and Japanese Star Anise -- Chapter 6: Sage -- Chapter 7: Savory and Tarragon -- Chapter 8: Thyme -- Chapter 9: Calamus or Sweet Flag -- Chapter 10: Horse Radish, Long Pepper or Pipli, Galangal -- Chapter 11:Quality Control.
    Abstract: This book is a compendium of rare and unique spices, which have been least researched but hold immense economic potential on a global scale. They are Aniseed, Shallot, Saffron, Caraway or Siah Zira, European or Indian Dill, Poppy, Star Anise and Japanese Star Anise, Sage, Savory, Tarragon, Thyme, Calamus or Sweet Flag, Horse Radish, Galangal, and Long Pepper or Pipli. Some of these are seed spices and others, like Saffron, are grown in the hills of Jammu and Srinagar, India and have varied uses, ranging from being very popular food flavorants to being used for religious purposes. Even within India, the country of the origin for most of the spices listed, many Indians are simply unaware of their immense economic potential. This is also the case with other countries, like Iran, where some spices, like Saffron, is widely used as a food flavorant. The book aims to be a unique compendium of these rare and unique spices to primarily enable researchers to tap into their great economic potential and, on a wider scale, help developmental agencies to tap into their immense potential in global spice trade. The book provides a cross-sectoral multi-scale assessment of developmental possibilities, globally, for rare and unique spices of immense economic importance. .
    Type of Medium: Online Resource
    Pages: IX, 141 p. 5 illus., 4 illus. in color. , online resource.
    Edition: 1st ed. 2023.
    ISBN: 9783031202490
    DDC: 641.3
    Language: English
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  • 187
    Keywords: Agriculture. ; Soil science. ; Plant biotechnology. ; Agronomy. ; Stress (Physiology). ; Plants. ; Plant diseases. ; Agriculture. ; Soil Science. ; Plant Biotechnology. ; Agronomy. ; Plant Stress Responses. ; Plant Pathology.
    Description / Table of Contents: 1. Soybean: A Key player for global food security -- 2. Dissection of Physiological and Biochemical Bases of Drought tolerance in Soybean (Glycine max) Using recent Phenomics approach -- 3. Soybean Improvement for Water-logging Tolerance -- 4. Salinity tolerance in Soybeans: Physiological, molecular and genetic perspectives -- 5. Utility of Network Biology Approaches to Understand the Aluminium Stress Responses in Soybean -- 6. Advances in Molecular markers to develop Soybean cultivars with increased protein and oil content -- 7. Soybean Breeding for Rust Resistance -- 8. Molecular breeding for resistance against pythium root rot (PRR) in soybean -- 9. Molecular Breeding for Resistance against Phytophthora in Soybean -- 10. Mitigation of Soybean Mosaic Virus Using an Efficient Molecular Approach -- 11. Transgenic Approach: A Key to Enrich Soybean Oil Quality -- 12. miRNAs in soybean improvement -- 13. Genome Editing Advances in Soybean Improvement against Biotic and Abiotic stresses.
    Abstract: Soybean (Glycine max L. (Merr)) is one of the most important crops worldwide. Soybean seeds are vital for both protein meal and vegetable oil. Soybean was domesticated in China, and since last 4-5 decades it has become one of the most widely grown crops around the globe. The crop is grown on an anticipated 6% of the world’s arable land, and since the 1970s, the area in soybean production has the highest percentage increase compared to any other major crop. It is a major crop in the United States, Brazil, China and Argentina and important in many other countries. The cultivated soybean has one wild annual relative, G. soja, and 23 wild perennial relatives. Soybean has spread to many Asian countries two to three thousand years ago, but was not known in the West until the 18th century. Among the various constraints responsible for decrease in soybean yields are the biotic and abiotic stresses which have recently increased as a result of changing climatic scenarios at global level. A lot of work has been done for cultivar development and germplasm enhancement through conventional plant breeding. This has resulted in development of numerous high yielding and climate resilient soybean varieties. Despite of this development, plant breeding is long-term by nature, resource dependent and climate dependent. Due to the advancement in genomics and phenomics, significant insights have been gained in the identification of genes for yield improvement, tolerance to biotic and abiotic stress and increased quality parameters in soybean. Molecular breeding has become routine and with the advent of next generation sequencing technologies resulting in SNP based molecular markers, soybean improvement has taken a new dimension and resulted in mapping of genes for various traits that include disease resistance, insect resistance, high oil content and improved yield. This book includes chapters from renowned potential soybean scientists to discuss the latest updates on soybean molecular and genetic perspectives to elucidate the complex mechanisms to develop biotic and abiotic stress resilience in soybean. Recent studies on the improvement of oil quality and yield in soybean have also been incorporated.
    Type of Medium: Online Resource
    Pages: VIII, 276 p. 37 illus., 36 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9783031122323
    DDC: 630
    Language: English
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  • 188
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Fungi. ; Mycology. ; Microbiology. ; Plant genetics. ; Plant biotechnology. ; Plants Evolution. ; Plants Development. ; Fungi. ; Plant Genetics. ; Plant Biotechnology. ; Plant Evolution. ; Plant Development.
    Description / Table of Contents: Foreword -- Part 1. Chaetomium: Biology to biotechnology -- Chapter 1. Taxonomy and Biodiversity of the Genus Chaetomium in Different Habitats -- Chapter 2. Developmental Morphology of Chaetomium and Chaetomiopsis -- Chapter 3. Molecular approaches for analyzing environmental Chaetomium diversity and exploitation of Chaetomium thermophilum for biochemical analyses -- Chapter 4. Recent advances on occurrence of genus Chaetomium on dung -- Chapter 5. Chaetomium in indoor environment and medically important species of Chaetomium -- Part 2. Metabolites of Chaetomium, the good, the bad and the ugly -- Chapter 6. Recent advancements on the role of biologically active secondary metabolites from Chaetomium -- Chapter 7. Chaetomium’s alkaloids -- Chapter 8. Applications of Chaetomium functional metabolites with special reference to antioxidants -- Chapter 9. Chaetomium enzymes and their applications -- Chapter 10. The use of Chaetomium taxa as biocontrol agents -- Chapter 11. Nanoparticles mediated Chaetomium, unique multifunctional Bullets: What Do We Need for Real Applications in Agriculture? -- Chapter 12. Biodegradation of agricultural wastes by Chaetomium species -- Chapter 13. Bioconversion of lignocellulosic residues into Single-Cell Protein (SCP) by Chaetomium -- Chapter 14. LIGHT, Electromagnetic Spectrum and Photostimulation of Microorganisms with special reference to Chaetomium -- Chapter 15. Chaetomium as potential soft rot degrader of woody and papery cultural heritage -- Chapter 16. Thermophilic Chaetomium in biotechnology -- Index.
    Abstract: Chaetomium genus was established by Gustav Kunze in 1817. According to Index Fungorum Partnership, there are 273 Chaetomium species accepted till now. Members of the genus Chaetomium are capable of colonizing various substrates and are well-known for their ability to degrade cellulose and to produce a variety of bioactive metabolites. More than 200 compounds have been reported from this genus. A huge number of new and bioactive secondary metabolites associated with unique and diverse structural types, such as chaetoglobosins, epipolythiodioxopiperazines, azaphilones, depsidones, xanthones, anthraquinones, chromones, and steroids, have been isolated and identified. Many of the compounds have been reported to possess significant biological activities, such as antitumor, antimalarial, cytotoxic, enzyme inhibitory, antimicrobial, phytotoxic, antirheumatoid and other activities. Chaetomium taxa are frequently reported to be cellulase and ligninase producers with the ability to degrade cellulosic and woody materials. This is the first, comprehensive volume covering Chaetomium genus in detail. It includes the latest research, methods, and applications, and was written by scholars working directly in the field. The book also contains informative illustrations and is fully referenced for further reading.
    Type of Medium: Online Resource
    Pages: XVI, 452 p. 121 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030316129
    Series Statement: Fungal Biology,
    DDC: 579.5
    Language: English
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  • 189
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Plant genetics. ; Plant biotechnology. ; Agriculture. ; Plant Genetics. ; Plant Biotechnology. ; Agriculture.
    Description / Table of Contents: Importance of duckweeds in basic research and its industrial applications -- Background history of the international Spirodela genome sequencing initiatives -- Cytogenetics and karyotype evolution of duckweeds -- Duckweed organelle genomes -- Repetitive sequences: Impacts and uses in the Spirodela genome -- Genotyping by sequencing of duckweeds -- Genome and transcriptome of Landoltia punctata -- Transcriptome responses of Spirodela polyrhiza -- Strategies & tools for sequencing duckweeds -- Transformation development in duckweeds.
    Abstract: This book tells the story behind the first Spirodela genome sequencing project. Further, it describes the current genomics applications of these findings, and efforts to sequence new genomes within the family. The closing chapters address the sequencing of the over 1 Gigabase Wolffia genomes, which could have major impacts on genome evolution and agricultural research. The duckweed or Lemnaceae family is a collection of 5 genera and 37 species of the smallest, fastest-growing flowering plants. Many of these aquatic monocotyledonous plants can grow all over the world, in a variety of climates. Given their simplified and neotenous morphology, duckweeds have been researched for several decades as a model species for plant physiology and ecotoxicological research, contributing to our understanding e.g. of flowering response, plant circadian systems, sulfur assimilation pathways and auxin biosynthesis. In addition, duckweed-based treatment has been a favorite and feasible means, especially in developing countries, of removing phosphorus and pharmaceutical chemicals from sewage and wastewater. With a dry annual mass yield per hectare of up to 80 tonnes (equivalent to 10 tonnes of protein), duckweed is also a promising aquatic crop in new modern and sustainable agriculture. Besides being an excellent primary or supplemental feedstock for the production of livestock and fish, duckweed biomass can be utilized as a potential resource for human nutrition, biofuel, or bioplastics, depending on water quality as well as protein or starch accumulating procedures. These academic and commercial interests have led to international efforts to sequence the Spirodela polyrhiza genome, the smallest and most ancient genome in the family.
    Type of Medium: Online Resource
    Pages: XVIII, 185 p. 30 illus., 21 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030110451
    Series Statement: Compendium of Plant Genomes,
    DDC: 581.35
    Language: English
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  • 190
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Biotechnology. ; Biomedical engineering. ; Radiology. ; Bioinformatics. ; Biotechnology. ; Biomedical Engineering and Bioengineering. ; Radiology. ; Computational and Systems Biology.
    Description / Table of Contents: Deep Learning in Medical Image Analysis -- Medical Image Synthesis via Deep Learning -- Deep Learning for Pulmonary Image Analysis: Classification, Detection, and Segmentation -- Deep Learning Computer Aided Diagnosis for Breast Lesion in Digital Mammogram -- Decision support system for lung cancer using PET/CT and microscopic images -- Lesion Image Synthesis using DCGANs for Metastatic Liver Cancer Detection -- Retinopathy analysis based on deep convolution neural network -- Diagnosis of Glaucoma on retinal fundus images using deep learning: detection of nerve fiber layer defect and optic disc analysis -- Automatic segmentation of multiple organs on 3D CT images by using deep learning approaches -- Techniques and Applications in Skin OCT Analysis -- Deep Learning Technique for Musculoskeletal Analysis -- Index.
    Abstract: This book presents cutting-edge research and applications of deep learning in a broad range of medical imaging scenarios, such as computer-aided diagnosis, image segmentation, tissue recognition and classification, and other areas of medical and healthcare problems. Each of its chapters covers a topic in depth, ranging from medical image synthesis and techniques for muskuloskeletal analysis to diagnostic tools for breast lesions on digital mammograms and glaucoma on retinal fundus images. It also provides an overview of deep learning in medical image analysis and highlights issues and challenges encountered by researchers and clinicians, surveying and discussing practical approaches in general and in the context of specific problems. Academics, clinical and industry researchers, as well as young researchers and graduate students in medical imaging, computer-aided-diagnosis, biomedical engineering and computer vision will find this book a great reference and very useful learning resource.
    Type of Medium: Online Resource
    Pages: VIII, 181 p. 131 illus., 114 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030331283
    Series Statement: Advances in Experimental Medicine and Biology, 1213
    DDC: 660.6
    Language: English
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  • 191
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Plant genetics. ; Plant biotechnology. ; Agriculture. ; Plant Genetics. ; Plant Biotechnology. ; Agriculture.
    Description / Table of Contents: Background and History of Tobacco -- Biodiversity of tobacco -- Genetics of tobacco -- The genome and transcriptome of tobacco and its ancestors -- SGN Tobacco resources and Nicotiana metabolic databases -- Leaf curing: a key step for tobacco chemistry -- Repetitive DNA dynamics and polyploidization in the genus Nicotiana (Solanaceae) -- Interspecific introgression in Nicotiana species -- Nicotine biosynthesis, transpssort, and regulation in tobacco: insights into the evolution of a metabolic pathway.
    Abstract: This book describes the history of tobacco genomics, from its “discovery” by Europeans to next-generation omics approaches in plant science. The authors primarily focus on the allotetraploid common tobacco plant (N. tabacum); however, separate chapters are dedicated to closely related Nicotiana species, such as N. benthamiana and N. attenuata, for which substantial progress in omics data analysis has been already achieved. While genetic maps, transcriptomes, and physical maps of BAC libraries have significantly enhanced our understanding of the tobacco plant, the genome of tobacco and related Nicotiana species has opened a new era in modern tobacco research. This book addresses current and future industrial and research applications as well as central challenges in tobacco science, including diseases, low variability of cultivars, the genome’s large size, polyploidy, and gene duplication.
    Type of Medium: Online Resource
    Pages: XIV, 263 p. 57 illus., 43 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030294939
    Series Statement: Compendium of Plant Genomes,
    DDC: 581.35
    Language: English
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  • 192
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Evolution (Biology). ; Paleontology . ; Anatomy, Comparative. ; Vertebrates. ; Animal migration. ; Physiology. ; Evolutionary Biology. ; Paleontology. ; Animal Anatomy. ; Vertebrate Zoology. ; Animal Migration. ; Animal Physiology.
    Description / Table of Contents: 1. Introduction to the morphology, development, and ecology of feathers -- 2. Molecular and cellular mechanisms of feather development provide a basis for diverse evolution of feather forms -- 3. The origin of birds: current consensus, controversy, and the occurrence of feathers -- 4. Integumentary structures in Kulindadromeus zabaikalicus, a basal neornithischian dinosaur from the Jurassic of Siberia -- 5. Filamentous integuments in non-avialan theropods and their kin: advances and future perspectives for understanding the evolution of feathers -- 6. Two of a feather: A comparison of the preserved integument in the juvenile theropod dinosaurs Sciurumimus and Juravenator from the Kimmeridgian Torleite Formation of southern Germany -- 7. Feather evolution in Pennaraptora -- 8. The feathers of the Jurassic Urvogel Archaeopteryx -- 9. The plumage of basal birds -- 10. A morphological review of the enigmatic elongated tail feathers of stem birds -- 11. Review on color patterns of fossil feathers -- 12. On the ancestry of feathers in Mesozoic dinosaurs.
    Abstract: Feathers are one of the most unique characteristics of modern birds and represent the most complex and colourful type of skin derivate within vertebrates, while also fulfilling various biological roles, including flight, thermal insulation, display, and sensory function. For years it was generally assumed that the origin of flight was the main driving force for the evolution of feathers. However, various discoveries of dinosaur species with filamentous body coverings, made over the past 20 years, have fundamentally challenged this idea and produced new evolutionary scenarios for the origin of feathers. This book is devoted to the origin and evolution of feathers, and highlights the impact of palaeontology on this research field by reviewing a number of spectacular fossil discoveries that document the increasing morphological complexity along the evolutionary path to modern birds. Also featuring chapters on fossil feather colours, feather development and its genetic control, the book offers a timely and comprehensive overview of this popular research topic. .
    Type of Medium: Online Resource
    Pages: VIII, 243 p. 80 illus., 71 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030272234
    Series Statement: Fascinating Life Sciences,
    DDC: 576.8
    Language: English
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  • 193
    Keywords: Plant diseases. ; Invertebrates. ; Agriculture. ; Plant Pathology. ; Invertebrate Zoology. ; Agriculture.
    Description / Table of Contents: Introduction . M.L. Gullino, R. Albajes, P. Nicot, J.C. van Lenteren -- Chapter1. Viral diseases. E. Moriones, E. Verdin -- Chapter2. Bacterial diseases. V. Catara, P. Bella -- Chapter3. Fungal diseases. M. Bardin, M.L. Gullino -- Chapter4. Insect and mite pests. M. Knapp, E. Palevsky, C. Rapisarda -- Chapter 5. Nematodes. F.X. Sorribas, C. Djian-Caporalino, T. Mateille -- Chapter6. Integrated Pest Management methods and considerations concerning implementation in greenhouses. J. Van Lenteren, P. Nicot -- Chapter7. 1. Epidemiology and population dynamics: modelisation, monitoring and management. G. Marchand, P.C. Nicot, R. Albajes, O. Carisse -- Chapter8. Diagnostics and identification of diseases, insects and mites. D. Spadaro, N. Agustí, S. F. Ortega, M.A. Hurtado Ruiz -- Chapter9. Host plant resistance to pests and pathogens, the genetic leverage in integrated pest and disease management. V. Lefebvre, N. Boissot, J-L. Gallois -- Chapter10. Cultural methods for greenhouse pest and disease management. M. Kruidhof, W.H. Elmer -- Chapter11Seed and Propagative material. G. Munkvold, M.L. Gullino -- Chapter12. Soil and substrate health. A. Gamliel -- Chapter13. Biocontrol agents against diseases. M. Bardin, M. Pugliese -- Chapter14. Biological control agents for control of pests in greenhouses. J. Van Lenteren, Ò. Alomar, W. Ravensberg, A. Urbaneja -- Chapter15. Chemical and natural pesticides in IPM: side-effects and application. M.L. Gullino, L. Tavella -- Chapter16. Implementation of IPDM in greenhouses: from research to the consumer. J. Riudavets, E. Moerman, E. Villa -- Chapter17. Tomatoes. C. Castañé, J. Van der Bloom, P.C. Nicot -- Chapter18. Sweet peppers. G. Messelink, R. Labbe, G. Marchand, L. Tavella -- Chapter19. Cucurbits. G. Messelink, F.J. Calvo, F. Marín, D.Janssen -- Chapter20. IPM for protecting leafy vegetables under greenhouses. B. Gard, G. Gilardi -- Chapter21. Implementation of IPDM in strawberries and other berries. S.K. Dara -- Chapter22. Ornamentals. M. Daughthrey, R. Buitenhuis -- Chapter23. Implementation of IPDM in greenhouses: customer value as guideline. J.S. Buurma and N.J.A. van der Velden -- Conclusion.
    Abstract: This book represents a new, completely updated, version of a book edited by two of the current editors, published with Springer in 1999. It covers pest and disease management of greenhouse crops, providing readers the basic strategies and tactics of integrated control together with its implementation in practice, with case studies with selected crops. The diversity of editors and authors provides readers a complete picture of the world situation of IPM in greenhouse crops. .
    Type of Medium: Online Resource
    Pages: IX, 691 p. 56 illus., 44 illus. in color. , online resource.
    Edition: 2nd ed. 2020.
    ISBN: 9783030223045
    Series Statement: Plant Pathology in the 21st Century, 9
    DDC: 571.92
    Language: English
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  • 194
    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Applied ecology. ; Forestry. ; Plant ecology. ; Ecology . ; Applied Ecology. ; Forestry. ; Plant Ecology. ; Theoretical and Statistical Ecology.
    Description / Table of Contents: Preface -- List of symbols -- 1. Introduction -- 2. Descriptive Models -- 3. Carbon Balance -- 4. Tree Structure -- 5. Carbon Balance and Structure -- 6. Competition -- 7. Tree structure revisited: Eco-evolutionary models -- 8. Predicting stand growth: parameters, drivers and modular inputs -- 9. Calibration -- 10. Applications and future outlook -- Solutions to Exercises -- References -- Author Index -- Index.
    Abstract: The book is designed to be a textbook for university students (MSc-PhD level) and a reference for researchers and practitioners. It is an introduction to dynamic modelling of forest growth based on ecological theory but aiming for practical applications for forest management under environmental change. It is largely based on the work and research findings of the authors, but it also covers a wide range of literature relevant to process-based forest modelling in general. The models presented in the book also serve as tools for research and can be elaborated further as new research findings emerge. The material in the book is arranged such that the student starts from basic concepts and formulations, then moves towards more advanced theories and methods, finally learning about parameter estimation, model testing, and practical application. Exercises with solutions and hands-on R-code are provided to help the student digest the concepts and become proficient with the methods. The book should be useful for both forest ecologists who want to become modellers, and for applied mathematicians who want to learn about forest ecology. The basic concepts and theory are formulated in the first four chapters, including a review of traditional descriptive forest models, basic concepts of carbon balance modelling applied to trees, and theories and models of tree and forest structure. Chapter 5 provides a synthesis in the form of a core model which is further elaborated and applied in the subsequent chapters. The more advanced theories and methods in Chapters 6 and 7 comprise aspects of competition through tree interactions, and eco-evolutionary modelling, including optimisation and game theory, a topical and fast developing area of ecological modelling under climate change. Chapters 8 and 9 are devoted to parameter estimation and model calibration, showing how empirical and process-based methods and related data sources can be bridged to provide reliable predictions. Chapter 10 demonstrates some practical applications and possible future development paths of the approach. The approach in this book is unique in that the models presented are based on ecological theory and research findings, yet sufficiently simple in structure to lend themselves readily to practical application, such as regional estimates of harvest potential, or satellite-based monitoring of growth. The applicability is also related to the objective of bridging empirical and process-based approaches through data assimilation methods that combine research-based ecological measurements with standard forestry data. Importantly, the ecological basis means that it is possible to build on the existing models to advance the approach as new research findings become available. .
    Type of Medium: Online Resource
    Pages: XVI, 310 p. 116 illus. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030357610
    DDC: 333.9516
    Language: English
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  • 195
    Keywords: Agricultural biotechnology. ; Subsistence farming. ; Agricultural genome mapping. ; Agricultural Biotechnology. ; Subsistence Agriculture. ; Agricultural Genetics.
    Description / Table of Contents: Chapter 1. Evolution of the Knowledge and Practice of Endophytic Microorganisms for Enhanced Agricultural Benefit and Environmental Sustainability -- Chapter 2. The Mycorrhizosphere Revisited – Multitrophic Interactions -- Chapter 3. Conservation Strategies for Rhizobiome in Sustainable Agriculture -- Chapter 4. Exploring the rhizosphere microbiome for sustainable agriculture production -- Chapter 5. From Rhizosphere to Endosphere: Bacterial-Plant Symbiosis and its impact on Sustainable Agriculture -- Chapter 6. Arbuscular Mycorrhizal fungal symbiosis for mutual benefit: More than expectation -- Chapter 7. Rhizodeposits- An essential component for microbial interactions in rhizosphere -- Chapter 8. Rhizospheric Microbial Diversity: Organic Vs. Inorganic Farming System -- Chapter 9. Rhizomicrobes: The underground life for sustainable agriculture -- Chapter 10. Synthetic biology tools in cyanobacterial biotechnology: recent developments and opportunities -- Chapter 11. The potential of rhizobacteria for plant growth and stress adaptation -- Chapter 12. Mycoremediation – An emerging technology for mitigating environmental contaminants -- Chapter 13. Exploration of Plant growth-promoting rhizobacteria (PGPR) for improving productivity and soil fertility under sustainable agricultural practices -- Chapter 14. Rhizosphere engineering for systemic resistance/tolerance to biotic and abiotic stress -- Chapter 15. Understanding the Microbiome Interactions across the Cropping System -- Chapter 16. Role of rhizosphere microorganisms in endorsing overall plant growth and development -- Chapter 17. Rhizospheric microbial community as drivers of soil ecosystem: Interactive microbial communication and its impact on plants -- Chapter 18. Rhizospheric Microbes and Plant Health -- Chapter 19. Omics approaches to unravel the features of rhizospheric microbiome -- Chapter 20. Rhizo-deposit and their role in rhizosphere interactions among the plant, microbe and other ecological components for crop management -- Chapter 21. Effects of Irrigation with Municipal Wastewater on the Microbiome of the Rhizosphere of Agricultural Lands -- Chapter 22. Plant-Rhizosphereic microbes interactions: enhancing plant growth and improving soil biota -- Chapter 23. Microbes mediated rhizospheric engineering for salinity stress mitigation -- Chapter 24. Metatranscriptomics of plant rhizosphere: A promising tool to decipher the role of microorganisms in plant growth and development -- Chapter 25. Rhizospheric engineering for sustainable production of horticultural crops.
    Abstract: The present book entitled, “Re-visiting the Rhizosphere Eco-system for Agricultural Sustainability” written by experts in the field, provides a comprehensive and consolidated state-of art overview of various aspects of rhizosphere biology, ecology and functioning. The role of rhizosphere microbial diversity in enhancing plant health and plant-microbe beneficial symbioses is discussed. Main topics include the diversity of plant-associated microbes in the rhizosphere, below-ground communication among the plant, soil, insects and microbes, rhizosphere ecosystem functioning, rhizosphere engineering, recruitment of microorganisms in the rhizosphere, mycorrhizal fungal symbiosis, positive interaction of the plants with the beneficial soil microorganisms for inducing the plant growth, conferring abiotic and biotic stress tolerance and modulating several pathways of the plants for the proper establishment and revitalization in the degraded and contaminated soils or negative likes the host-pathogen interactions leading to the disease development in plants. Further chapters focus on the role of signaling during the different stages of the plant-microbe coexistence, in symbiotic or pathogenic relationships, in quorum sensing, microbial signaling and cross-talk, bio-film formation, and antimicrobial peptides. The book also discusses the application of microbes in biodegradation of xenobiotic contaminants, bioremediation of heavy metals, sustainable agriculture and soil health, biological control of insect pests and plant pathogens, and the latest tools of omics which offer pioneering approaches to the exploration of microbial structure and function, secretome, holobiome, below-ground interaction, and microbial cooperation for sustainable food production and enhanced resource acquisition. Descriptions of cutting-edge techniques and novel approaches make this book unique in the area of rhizosphere biology. This is a useful reading material for researchers and students of microbiology, agriculture, ecology, and rhizosphser studies.
    Type of Medium: Online Resource
    Pages: XXI, 537 p. 37 illus. in color. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811941016
    Series Statement: Rhizosphere Biology,
    DDC: 630
    Language: English
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  • 196
    Online Resource
    Online Resource
    Singapore :Springer Nature Singapore :
    Keywords: Botany. ; Agriculture. ; Plant molecular biology. ; Botanical chemistry. ; Plant Science. ; Agriculture. ; Plant Molecular Biology. ; Plant Biochemistry.
    Description / Table of Contents: Chapter 1. Plant Metal and Metalloid Transport -- Chapter 2. Heavy Metals: Transport in Plants and their Physiological and Toxicological Effects -- Chapter 3. The Role of ABC Transporter in Metal Tranasport in Plants -- Chapter 4. Cadmium, A Non-Essential Heavy Metal: Uptake, Translocation, Signaling, Detoxification, and Impact on Amino Acid Metabolism -- Chapter 5. Natural Resistance Associated Macrophage Proteins (NRAMP): Functional Significant of Metal Transport in Plants -- Chapter 6. Role of Heavy Metal Atpases in Transport of Cadmium and Zinc in Plants -- Chapter 7. The Versatile Role of Plant Aquaglyceroporins in Metalloid Transport -- Chapter 8. The Multidrug and Toxic Compound Extrusion (MATE) Family in Plants and Their Significance in Metal Transport -- Chapter 9. Molecular Mechanism of Aluminium Tolerance in Plants: An Overview -- Chapter 10. Functional, Structural, and Transport Aspects of ZIP in Plant -- Chapter 11. The Function of HAK as K+ Transporter and AKT as Inward Rectifying Agent in The K+ Channel -- Chapter 12. The Mechanism of Silicon Transport in Plants -- Chapter 13. The Copper Transport Mechanism in Plants -- Chapter 14. Plant Metal Tolerance Proteins: Insight Into their Roles in Metal Transport and Homeostasis for Future Biotechnological Applications -- Chapter 15. Co-Transport Mechanism in Plants for Metals and Metalloids -- Chapter 16. Metal Nanoparticles Implication, Transport, and Detection in Plants -- Chapter 17. Transcription Factors and Metal Stress Signalling in Plants -- Chapter 18. Heavy Metal Transporters, Phytoremediation Potential and Biofortification -- Chapter 19. Phytoremediation and Biofortification: Contrasting Yet Similar Approaches of Manipulating Plant Metal(Loid) Homeostasis for Societal Benefit.
    Abstract: This edited book stands as a one place knowledge hub for plant metal(loid) transporters. The book comprehensively covers holistic aspect of metal(loid) transporters involved in uptake and translocation of essential as well as toxic metal(loid)s. Essential and beneficial metal(loid)s are required in every biological process for normal plant growth and development, however in excess they are toxic. There are toxic metal(loid)s also whose accumulation in plants interferes with normal cellular functioning and hampers growth of plants. Hence, metal(loid) uptake and accumulation in plants is a highly regulated phenomenon involving the role of several transporters, enzymes, metabolites, transcription factors and post translational modifications. The book contains chapters from the experts and the contents of the book are presented in simple language and represented through beautiful and scientifically informative figures and tables. This book is of interest to teachers, researchers, doctoral and graduate students working in the area of plant physiology, environmental biotechnology, plant biotechnology metal(loid) stress, phytoremediation and crop biofortification.
    Type of Medium: Online Resource
    Pages: XIII, 454 p. 1 illus. , online resource.
    Edition: 1st ed. 2022.
    ISBN: 9789811961038
    DDC: 580
    Language: English
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  • 197
    Keywords: Veterinary medicine. ; Medicine Research. ; Biology Research. ; Biometry. ; Veterinary Science. ; Biomedical Research. ; Biostatistics.
    Description / Table of Contents: An introduction to reproducibility in the context of animal research -- Rodent Genetics -- Animal and environmental factors that influence reproducibility -- Microbiology and Microbiome -- Effects of untreated pain, anesthesia and analgesia in animal experimentation -- Why do we need a statistical experiment design -- Statistical tests and Sample size calculations -- Design of experiments -- Scholarly Publishing and Scientific Reproducibility -- Systematic reviews -- Planning animal experiments.
    Abstract: This highly-readable text provides grounds on how to plan and conduct animal experiments that can be reproduced by others. The book touches on factors that may impact the reproducibility of animal studies including: the animal genetic background, the animal microbial flora, environmental and physiological variables affecting the animal, animal welfare, statistics and experimental design, systematic reviews of animal studies, and the publishing process. The book addresses advanced undergraduates, graduate students and all scientists working with animals.
    Type of Medium: Online Resource
    Pages: VI, 277 p. 52 illus., 39 illus. in color. , online resource.
    Edition: 1st ed. 2021.
    ISBN: 9783030661472
    Series Statement: Laboratory Animal Science and Medicine, 1
    DDC: 636.089
    Language: English
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  • 198
    Keywords: Developmental biology. ; Zoology. ; Cytology. ; Developmental Biology and Stem Cells. ; Zoology. ; Cell Biology.
    Description / Table of Contents: Foreword - A brief history of Spermatology -- Part I: Overview -- Chapter 1: Overview of reproduction systems in aquatic animals -- Part II: Basic knowledge of male gametes in aquatic animals -- Chapter 2: Introduction to sperm motility of aquatic animals -- Chapter 3: Sperm activation and chemotaxis of invertebrates -- Chapter 4: Fish sperm activation -- Chapter 5: Sperm guidance in Teleosts -- Part III: Basic knowledge of female gametes and sperm-egg interaction in aquatic animals -- Chapter 6: Structure of mature oocytes -- Chapter 7: Oocyte maturation and fertilization in Mollusks and other Protostomes -- Chapter 8: Reproduction of the corals Acropora -- Chapter 9: Self- and nonself-recognition of gametes in Ascidians -- Chapter 10: Reproduction of Elasmobranchs -- Chapter 11: Fertilization in Amphibians -- Part IV: Behavior, ecology and reproductive strategies -- Chapter 12: Sperm motility and fertilization of sea urchins -- Chapter 13: Behavior and fertilization of Squids -- Part V: Biotechnology in aquatic species -- Chapter 14: Improvements on the reproductive control of the European eel -- Chapter 15: Sperm cryopreservation of aquatic species -- Chapter 16: Germ cells transplantation in Sturgeon -- Chapter 17: Germ cell transplantation in tuna.
    Abstract: This book provides an up-to-date overview of the various reproductive systems of a variety of aquatic animals, from invertebrates to fishes. While all terrestrial animals use internal fertilization, aquatic animals have diverse reproductive systems. Some are internal fertilizers with or without mating, but many perform external fertilization. Because of this diversity, the reproductive systems of aquatic animals represent excellent models for the study of adaptive evolution and the species specificity of fertilization. In addition, many aquatic animals, including fish, crustaceans, and mollusks, are important as fishery and aquaculture resources. In this book, up-and-coming researchers examine reproductive systems in representative aquatic animals, covering both the basic knowledge and late-breaking results. Reproduction in Aquatic Animals: From Basic Biology to Aquaculture Technology will be of interest to graduate and postgraduate students in biology and agricultural sciences, as well as to researchers and technicians in the fields of reproductive biology and fishery science and to non-academics.
    Type of Medium: Online Resource
    Pages: VIII, 379 p. 63 illus., 34 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9789811522901
    DDC: 571.8
    Language: English
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    Online Resource
    Online Resource
    Cham :Springer International Publishing :
    Keywords: Freshwater ecology. ; Marine ecology. ; Plant physiology. ; Biotic communities. ; Population biology. ; Plant ecology. ; Freshwater and Marine Ecology. ; Plant Physiology. ; Community and Population Ecology. ; Plant Ecology.
    Description / Table of Contents: Antarctic Seaweeds: Biogeography, Adaptation and Ecosystem Services -- Diversity of Antarctic Seaweeds -- Biogeographic Processes Influencing Antarctic and Sub-Antarctic Seaweeds -- Detached Seaweeds as Important Dispersal Agents Across the Southern Ocean.-Biogeography of Antarctic Seaweeds Facing Climate Changes -- Comparative Phylogeography of Antarctic Seaweeds: Genetic Consequences of Historical Climatic Variations -- Underwater Light Environment of Antarctic Seaweeds -- Production and Biomass of Seaweeds in Newly Ice-Free Areas: Implications for Coastal Processes in a Changing Antarctic Environment -- Carbon Balance Under a Changing Light Environment -- Life History Strategies, Photosynthesis and Stress Tolerance in Propagules of Antarctic Seaweeds -- Form and Function in Antarctic Seaweeds: Photobiological Adaptations, Zonation Patterns and Ecosystem Feedbacks -- Successional Processes in Antarctic Benthic Algae -- Seaweed-Herbivore Interactions: Grazing as Biotic Filtering in Intertidal Antarctic Ecosystems -- Diversity and Functioning of Antarctic Seaweed Microbiomes -- Seaweeds in the Antarctic Marine Coastal Food Web -- Trophic Networks and Ecosystem Functioning -- Chemical Mediation of Antarctic Macroalgal-Grazer Interactions -- Brown Algal Phlorotannins: An Overview of their Functional Roles.
    Abstract: Seaweeds (macroalgae) represent the most striking living components in the Antarctic’s near-shore ecosystems, especially across the West Antarctic Peninsula and adjacent islands. Due to their abundance, their central roles as primary producers and foundation organisms, and as sources of diverse metabolically active products, seaweed assemblages are fundamental to biogeochemical cycles in Antarctic coastal systems. In recent years, the imminence of climate change and the direct impacts of human beings, which are affecting vast regions of the Antarctic, have highlighted the importance of seaweed processes in connection with biodiversity, adaptation and interactions in the benthic network. Various research groups have been actively involved in the investigation of these topics. Many of these research efforts have a long tradition, while some “newcomers” have also recently contributed important new approaches to the study of these organisms, benefiting polar science as a whole. This book provides an overview of recent advances and insights gleaned over the past several years. Focusing on a timely topic and extremely valuable resource, it assesses the challenges and outlines future directions in the study of Antarctic seaweeds.
    Type of Medium: Online Resource
    Pages: XIV, 397 p. 68 illus., 63 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030394486
    DDC: 577.6
    Language: English
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    Online Resource
    Cham :Springer International Publishing :
    Keywords: Medicine Research. ; Biology Research. ; Geriatrics. ; Ophthalmology. ; Pathology. ; Cytology. ; Pharmacy. ; Biomedical Research. ; Geriatrics. ; Ophthalmology. ; Pathology. ; Cell Biology. ; Pharmacy.
    Description / Table of Contents: Chapter 1. Literature review -- Chapter 2. Results of experimental studies of short peptides (cytogens) in ophthalmology -- Chapter 3. Results of the clinical study of short peptides (cytogens) in ophthalmology -- Conclusion.
    Abstract: This book discusses the pathology of the retina, and reviews current research on the use of cell replacement therapy and short peptides to restore functional activity in retinal neurons. As the book describes, pathologies of the retina, including age-related macular degeneration, diabetic retinopathy, and retinitis pigmentosa, present a long-standing challenge in the practice of clinical ophthalmology. Modern treatment for these conditions, which lead to irreversible blindness, includes laser exposure, surgical intervention, and drugs. These treatments aim to reduce the risk of new complications in the eye; pathogenetic therapy of degenerative diseases of the retina is practically absent in current ophthalmic practice. The first section of the book reviews the molecular mechanisms of age-related macular degeneration, diabetic retinopathy, and retinitis pigmentosa, and reports on methods of treatment. The second section presents the results of recent experimental studies of the effects of short peptides on pluripotent embryonic cells; on proliferative activity in retinal cells and pigment epithelium; on expression of markers of differentiation or retinal neurons and pigment epithelium; and on the course of hereditary retinal pigmentation in Campbell rats. The third section offers results of clinical studies on the effectiveness of short peptides in patients with macular degeneration, and in patients with retinitis pigmentosa. The author concludes that the regular use of peptides in the treatment of degenerative diseases of the retina can slow the progression of the pathological process and preserve the patient’s vision for some 10-15 years. In addition, in 80 percent of patients, it is possible to increase visual function by increasing visual acuity, improving the boundaries of the visual field and the fundus.
    Type of Medium: Online Resource
    Pages: VI, 90 p. 17 illus., 11 illus. in color. , online resource.
    Edition: 1st ed. 2020.
    ISBN: 9783030501600
    DDC: 610.72
    Language: English
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