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Isolate-specific S-antigen of Plasmodium falciparum contains a repeated sequence of eleven amino acids

Nature volume 306, pages 751–756 (1983)Cite this article

Abstract

Antibodies raised against a Plasmodium falciparum protein expressed in Escherichia coli reacted with a 220,000-molecular weight antigen of mature blood-stage parasites. The protein resembles the sporozoite surface antigen being composed of tandem repeats of 11 amino acids. However, it is isolate-specific and the encoding gene is not detectable in strains that do not express the protein.

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Authors and Affiliations

  1. The Walter and Eliza Hall Institute of Medical Research, Royal Melbourne Hospital, Post Office, Victoria, 3050, Australia

    Ross L. Coppel, Alan F. Cowman, Klaus R. Lingelbach, Graham V. Brown, Robert B. Saint, David J. Kemp & Robin F. Anders

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  1. Ross L. Coppel
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  2. Alan F. Cowman
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  3. Klaus R. Lingelbach
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  4. Graham V. Brown
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  6. David J. Kemp
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  7. Robin F. Anders
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Coppel, R., Cowman, A., Lingelbach, K. et al. Isolate-specific S-antigen of Plasmodium falciparum contains a repeated sequence of eleven amino acids. Nature 306, 751–756 (1983). https://doi.org/10.1038/306751a0

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