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Flow cytometry in toxicity analysis

Abstract

The well-established clinical research tool of flow cytometry has now been applied to the detection of toxic injury to the cells of organisms exposed to environmental contaminants

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References

  1. Deaven, L.L. in Cytogenetic Assays of Environmental Mutagens (ed. Hsu, T.C.) 325–351 (Allanheld, Osmun & Co.,Totowa, NJ, 1982).

    Google Scholar 

  2. Siegel, E. B. Regul. Tox. Pharmac. 4, 287–304 (1984).

    Article  CAS  Google Scholar 

  3. Gray, J. et al. Clin. Chem. 21, 1258–1262 (1975).

    CAS  PubMed  Google Scholar 

  4. Laerum, O. D. & Farsund, T. Cytometry 2, 1–13 (1981).

    Article  CAS  Google Scholar 

  5. Everson, D., Traganos, F., Darzynkiewicz, Z., Staiano-Colco, L. & Melamed, M. J. natn. Cancer Inst. 64, 857–863 (1980).

    Google Scholar 

  6. Olszewski, W., Darzynkiewicz, Z., Rosen, P., Schwartz, M. & Melamed, M. Cancer 48, 980–984 (1981).

    Article  CAS  Google Scholar 

  7. Otto, F. & Oldiges, H. Cytometry 1, 13–17 (1980).

    Article  CAS  Google Scholar 

  8. Deaven, L., Oka, M. & Tobey, R. J. natn. Cancer Inst. 60, 1155–1161 (1978).

    Article  CAS  Google Scholar 

  9. Otto, F., Oldiges, H., Gohde, W. & Jain, V.K. Cytometry 2, 189–191 (1981).

    Article  CAS  Google Scholar 

  10. Dallas, C. E., Mellard, D. N., Theiss, J. C., Pentecost, A. R. & Fairchtld, E. J. Envir. Res. 43, 191–202 (1987).

    Article  CAS  Google Scholar 

  11. McBee, K. & Bickham, J. W. Bull. Envir. Contam. Tox. 40, 343–349 (1988).

    Article  CAS  Google Scholar 

  12. Lamb, T., Bickham, J. W., Gibbons, J. W., Smolen, M. J. & McDowell, S. Arch. Envir. Contam. Tox. (in the press) (1990).

  13. George, L. S., Dallas, C. E., Brisbin, I. L. & Evans, D. L. Toxicologist 10, 248 (1990).

    Google Scholar 

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Dallas, C., Evans, D. Flow cytometry in toxicity analysis. Nature 345, 557–558 (1990). https://doi.org/10.1038/345557a0

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