Perception of cold and hot is one of life's essentials. Three research teams find that, when a temperature-sensing receptor is deleted in mice, the animals lose their response to a range of cold temperatures.
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References
Bernstein, J. Die fünf Sinne des Menschen (Brockhaus, Leipzig, 1875).
Voets, T., Talavera, K., Owsianik, G. & Nilius, B. Nature Chem. Biol. 1, 85–92 (2005).
Dhaka, A., Viswanath, V. & Patapoutian, A. Annu. Rev. Neurosci. 29, 135–161 (2006).
Colburn, R. W. et al. Neuron 54, 379–386 (2007).
Dhaka, A. et al. Neuron 54, 371–378 (2007).
Bautista, D. M. et al. Nature 448, 204–208 (2007).
McKemy, D. D., Neuhausser, W. M. & Julius, D. Nature 416, 52–58 (2002).
Proudfoot, C. J. et al. Curr. Biol. 16, 1591–1605 (2006).
Chung, M. K. & Caterina, M. J. Neuron 54, 345–347 (2007).
Zimmermann, K. et al. Nature 447, 856–859 (2007).
Hensel, H. & Zotterman, Y. J. Neurophysiol. 14, 377–385 (1951).
Schmidt, R. F. & Thews, G. Physiologie des Menschen 214–217 (Springer, Heidelberg, 1990).
Lee, H. & Caterina, M. J. Pflügers Arch. Eur. J. Physiol. 451, 160–167 (2005).
Conti, B. et al. Science 314, 825–828 (2006).
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Nilius, B., Voets, T. Channelling cold reception. Nature 448, 147–148 (2007). https://doi.org/10.1038/448147a
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DOI: https://doi.org/10.1038/448147a
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