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Urinary Excretion Patterns of Individual Acid Mucopolysaccharides

Nature volume 213, pages 1132–1133 (1967)Cite this article

Abstract

DURING recent years several authors have shown that certain hereditary dysostoses are caused by an abnormal deposition in bone and various parenchymatous organs of acid mucopolysaccharides (AMP). Maroteaux and Lamy1 subdivided these mucopolysaccharidoses into five different types according to their characteristic excretion patterns of AMP. In this communication we present our results of a comparable investigation of urinary excretion of individual AMP in normal persons and patients with different types of mucopolysaccharidoses. Through the introduction of column chromatography the determination of AMP pattern in the urine has become an especially valuable tool in the biochemical identification and classification of atypical cases of hereditary dysplasias of bone.

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References

  1. Maroteaux, P., and Lamy, M., J. Pediat., 67, 312 (1965).

    Article  Google Scholar 

  2. Schiller, S., Slover, G. A., and Dorfman, A., J. Biol. Chem., 236, 983 (1961).

    CAS  PubMed  Google Scholar 

  3. Dische, Z., J. Biol. Chem., 167, 189 (1947).

    CAS  PubMed  Google Scholar 

  4. Roe, J. H., J. Biol. Chem., 212, 335 (1955).

    CAS  PubMed  Google Scholar 

  5. Teller, W., and Ziemann, A., Klin. Wschr., 44, 1142, (1966).

    Article  CAS  Google Scholar 

  6. Balazs, E. A., and Jeanloz, R. W., The Aminosugars, IIa (Academic Press, New York–London, 1965).

    Google Scholar 

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Authors and Affiliations

  1. Department of Pediatrics, University of Marburg a.d. Lahn, Germany

    W. M. TELLER

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  1. W. M. TELLER
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TELLER, W. Urinary Excretion Patterns of Individual Acid Mucopolysaccharides. Nature 213, 1132–1133 (1967). https://doi.org/10.1038/2131132a0

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