Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Presence of an Additional Metacentric Chromosome in AKR/TIALD Leukaemic Cells

Nature volume 225, pages 737–738 (1970)Cite this article

Abstract

THE cells of human and murine leukaemias are usually either diploid or very close to diploidy, even when their karyotypes show some specific morphological abnormalities. In a study of spontaneous and transplanted AKR leukaemias, Wakonig-Vaartaja and Stich1 found that most of the mitoses had a normal diploid set of forty chromosomes although there were forty-one chromosomes in one-third of the cases. Identical observations have been reported by Kurita and Yosida2.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Wakonig-Vaartaja, R., and Stich, H. F., J. Nat. Cancer Inst., 25, 295 (1960).

    Google Scholar 

  2. Kurita, Y., and Yosida, T. H., Gann, 52, 257 (1961).

    CAS  PubMed  Google Scholar 

  3. Leonard, A., and Deknudt, G. H., Nature, 214, 504 (1967).

    Article  ADS  CAS  Google Scholar 

  4. Koller, P. C., Europ. J. Cancer, 3, 279 (1967).

    Article  CAS  Google Scholar 

  5. Ford, C. E., in Tissue Grafting and Radiation (Academic Press, New York, 1966).

    Google Scholar 

  6. Duplan, J. F., Nouv. Revue Fr. Hémat., 2, 551 (1962).

    Google Scholar 

  7. Lejeune, J., and Berger, R., CR Acad. Sci., Paris, 263, 1880 (1966).

    CAS  Google Scholar 

  8. Lejeune, J., Berger, R., Haines, M., Lafourcade, J., Vialatte, J., Satge, P., and Turpin, R., CR Acad. Sci., Paris, 256, 1195 (1963).

    Google Scholar 

  9. De Grouchy, J., and Wolff, E., Europ. J. Cancer, 5, 159 (1969).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratoire Pasteur, 26 Rue d'Ulm, 75, Paris, 5°

    E. LEGRAND & J. F. DUPLAN

Authors
  1. E. LEGRAND
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. F. DUPLAN
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

LEGRAND, E., DUPLAN, J. Presence of an Additional Metacentric Chromosome in AKR/TIALD Leukaemic Cells. Nature 225, 737–738 (1970). https://doi.org/10.1038/225737a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/225737a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing