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Nonspecific cross reacting antigen as a marker for human polymorphs, macrophages and monocytes

Nature volume 255, pages 714–716 (1975)Cite this article

Abstract

WE have described1 an antigen able to cross react with the carcinoembryonic antigen of the digestive system (CEA) and named it nonspecific cross reacting antigen (NCA) because of its reaction with CEA and its lack of tissue and cancer specificity. NCA was found in perchloric extracts of gastrointestinal tumours and in lesser amounts in those of non-cancerous mucosa, lung and spleen. The same antigen has been described under different names (NGP, CCEA II) in other laboratories2,3. We pointed out that NCA bore a specific antigenic determinant not shared by CEA1.

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Authors and Affiliations

  1. Laboratoire d'Immunochimie, Institut de Recherches sur le Cancer, Villejuif, France

    P. BURTIN, P. C. QUAN & M. C. SABINE

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  1. P. BURTIN
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  2. P. C. QUAN
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  3. M. C. SABINE
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BURTIN, P., QUAN, P. & SABINE, M. Nonspecific cross reacting antigen as a marker for human polymorphs, macrophages and monocytes. Nature 255, 714–716 (1975). https://doi.org/10.1038/255714a0

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