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Stimulation by Insulin of in vitro Fat Synthesis by Mammary Tissue studied with Carbon-14 and Tritium

Nature volume 168, pages 1083–1084 (1951)Cite this article

Abstract

RESPIRATORY observations have been interpreted1 as indicating that lactating mammary gland slices are able to utilize acetate for net fatty-acid synthesis in vitro, either as sole substrate (ruminants: sheep, goat, cow) or in the presence of glucose (non-ruminants: rat, rabbit). Tissue respiration measurements have, moreover, led to the further conclusion2–4 that insulin, added in vitro, causes a marked stimulation of fat synthesis by lactating mammary gland slices from rat, rabbit and mouse.

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References

  1. Folley, S. J., and French, T. H., Biochem. J., 46, 465 (1950).

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  2. Balmain, J. H., French, T. H., and Folley, S. J., Nature, 165, 807 (1950).

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  3. Balmain, J. H., and Folley, S. J., Biochem. J., 48, i (1951).

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Authors and Affiliations

  1. National Institute for Research in Dairying, Shinfield, Nr. Reading

    JUDITH H. BALMAIN, S. J. FOLLEY & R. F. GLASCOCK

Authors
  1. JUDITH H. BALMAIN
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  2. S. J. FOLLEY
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  3. R. F. GLASCOCK
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BALMAIN, J., FOLLEY, S. & GLASCOCK, R. Stimulation by Insulin of in vitro Fat Synthesis by Mammary Tissue studied with Carbon-14 and Tritium. Nature 168, 1083–1084 (1951). https://doi.org/10.1038/1681083a0

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