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Chromatographic Behaviour of Hæmoglobin E

Abstract

RECENTLY, the chromatographic separation of four different human carboxyhæmoglobins (normal adult (A), sickle cell (B),C and fœtal (F) on the ion exchange resin ‘Amberlite IRC 50’ (XE 64) has been reported by us1. It was shown that these hæmoglobins move down the column at different rates in the sequence F > A > B > C. Now we are able to describe the behaviour of a third abnormal human hæmoglobin (E), using the same chromatographic method.

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References

  1. Prins, H. K., and Huisman, T. H. J., Nature, 175, 903 (1955).

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  2. Jonxis, J. H. P., Huisman, T. H. J., Van der Schaaf, P. C., and Prins, H. K., Nature [177, 627 (1956)].

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  3. Morrison, M., and Cook, J. L., Science, 122, 920 (1955).

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PRINS, H., HUISMAN, T. Chromatographic Behaviour of Hæmoglobin E. Nature 177, 840–841 (1956). https://doi.org/10.1038/177840b0

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