Abstract
PRELIMINARY linkage tests with the house mouse mutant ‘crinkled’1 showed a deficiency of recombinations between crinkled and flexed-tail2 in repulsion inter-cross matings. Owing to a serious shortage of flexed-tail segregants, back-cross matings in coupling and repulsion were set up to estimate the percentage recombination between these loci. Because of the lack of vigour of crinkled flexed-tail homozygotes, these could only be used as male parents. Consequently, the recombination observed refers to that of doubly heterozygous females. Flexed-tail was classified within 24 hr. of birth by the transient anæmia visible at that age, and crinkled at 1–2 weeks of age by the appearance of the coat and tail. The number of offspring from the back-cross matings are given in Table 1.
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References
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KING, J. Linkage Group XIV of the House Mouse. Nature 178, 1126–1127 (1956). https://doi.org/10.1038/1781126a0
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DOI: https://doi.org/10.1038/1781126a0
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