Abstract
IN the past, numerous attempts to select strains of different plasmodia resistant to 4-amino-quinoline have been unsuccessful1. Recently, a successful attempt was recorded for Plasmodium gallinaceum, in which the resistance to chloroquine was found to be two-fold2. We have now succeeded in selecting a strain of mammalian plasmodium which is 200 times as tolerant to chloroquine as the parent strain.
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Ray, A. P., and Sharma, G. K., Nature, 178, 1291 (1956).
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RAMAKRISHNAN, S., PRAKASH, S. & CHOUDHURY, D. Selection of a Strain of Plasmodium berghei highly resistant to Chloroquine (‘Resochin’). Nature 179, 975 (1957). https://doi.org/10.1038/179975a0
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DOI: https://doi.org/10.1038/179975a0
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