Abstract
As results of various surveys on the occurrence of hæmoglobinopathies in different countries become available it appears that the number of carriers of one of these hereditary aberrations is relatively high among the populations of many countries: Central and North Africa, Italy, Greece, the Middle Eastern countries, Iran, India, Pakistan, Ceylon, Burma, Thailand and Indonesia. In many of these countries malaria is common. There are positive indications that the presence of hæmoglobins S and F lowers the mortality-rate of young children infected with malaria. For the other abnormal hæmoglobins such a relation has not yet been established. Lie Injo Luan Eng1 found among the Sudanese and Javanese populations of Java respectively that 2.5 and 4.5 per cent were carriers of hæmoglobin E. Lehmann et al.2 found 13.1 and 5 per cent respectively in the Malaysian Malays of two districts. In the Dyaks of Sarawak the number of hæmoglobin E carriers was found to be very low3. Farther east, in the Celebes, the percentage of carriers of hæmoglobin E was found to be low (1 per cent). Lie Injo Luan Eng1 and Lehmann et al.4 found no abnormal hæmoglobin in the Australian aborigines.
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References
Lie Injo Luan Eng, thesis, Jakarta (1956).
Lehmann, H., and Rhagwan Singh, R., Nature, 178, 695 (1956).
Colbourne, M. J., Ikin, E. W., Mourant, A. E., Lehmann, H., and Thein, H., Nature, 181, 119 (1958).
Horsfall, W. R., and Lehmann, H., Nature, 177, 41 (1956).
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JONXIS, J., HUISMAN, T., DA COSTA, G. et al. Absence of Abnormal Hæmoglobins in Some Groups of the Papua Population of Dutch New Guinea. Nature 181, 1279 (1958). https://doi.org/10.1038/1811279a0
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DOI: https://doi.org/10.1038/1811279a0
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