Abstract
SOME striking toxic effects have been described for certain antibilharzial compounds1,2,3. These consist of visual impairment and loss of hair in laboratory animals. More recently4, the activity and toxicity of some N-p-aminophenoxy-alkylamides have been described in experimental schistosomiasis. One of these compounds*, 1-p-aminophenoxy-5-phthalimidopentane, (M and B 2948A)(I), has been tested for its effect against liver fluke in sheep and the purpose of this note is to describe the toxic effects observed. When given orally to sheep this compound was observed to produce a remarkable loss of wool.
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References
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HUGHES, D. Loss of Wool in Sheep caused by 1-p-Amino-phenoxy-5-phthalimidopentane. Nature 184, 1644–1645 (1959). https://doi.org/10.1038/1841644a0
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DOI: https://doi.org/10.1038/1841644a0
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