Abstract
DELAYED, or tuberculin-type, sensitivity occurs in the course of many bacterial infections. It is characterized by skin reactions appearing with 24–48 hr. after intracutaneous injections of bacteria or their soluble products. Like immunological reactions, delayed skin reactions are highly specific, but the products eliciting the reactions need not be antigenic per se. Circulating antibodies have not been demonstrated to play a part. Delayed sensitivity is not transferable passively by serum, but can be transferred with the cells of sensitized organisms.
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References
Raffel, S., J. Infect. Dis., 82, 267 (1948).
Braude, A. I., “A Comparison of Sensitivity to Tuberculin and Bacterial Endotoxin by means of Isotopes”, Ann. Rep. Research and Development Division, Office of the Surgeon General, October 31, 1958, pp. 27–52 (Department of the Army, Washington 25, D.C.).
Ovary, Z., Prog. Allergy, 5, 459 (1958).
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BLOCH, H., NORDIN, A. Production of Tuberculin Sensitivity. Nature 187, 434–435 (1960). https://doi.org/10.1038/187434a0
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DOI: https://doi.org/10.1038/187434a0
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