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Conditions influencing the Stability of Human Antihæmophilic Factor

Abstract

THE lability of human antihæmophilic factor in both plasma and concentrates is a major hazard during purification, even when the reaction of solutions is maintained within the rather restricted optimum range of stability, which we find to be pH 7.1–7.2, and when preparative procedures are conducted at temperatures close to 0°.

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KEKWICK, R., WALTON, P. Conditions influencing the Stability of Human Antihæmophilic Factor. Nature 194, 878–879 (1962). https://doi.org/10.1038/194878a0

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