Elsevier

Aquaculture

Volume 36, Issues 1–2, 1 January 1984, Pages 71-83
Aquaculture

Induction of ovulation in goldfish, Carassius auratus, by pimozide and analogues of LH-RH

https://doi.org/10.1016/0044-8486(84)90055-3Get rights and content

Abstract

The effects of intraperitoneal injections or pellet implantations of luteinizing hormone-releasing hormone analogues, des-Gly10-[D-ALA6]-LH-RH-ethylamide (LRH-Aa) or des-Gly10-[D-Trp6]-LH-RH-ethylamide (LRH-At), respectively, and the combination of these treatments with pimozide, a dopamine antagonist, on serum gonadotropin (GtH) and ovulation in goldfish held at 18–20°C were investigated. Injections of LRH-Aa (0.1 μg/g body weight) or pellet implants of LRH-At (25 and 125 μg/fish) alone increased serum GtH levels, but were relatively ineffective for inducing ovulation in goldfish (≅ 25% rate of occurrence). Pimozide greatly potentiated the GtH release response to LRH-Aa injections or LRH-At pellet implantations. A high rate of occurrence of ovulation (87%) was observed within 24 h when pimozide was injected prior to or with the first of two injections of LRH-Aa, or following implantations of LRH-At pellets that give continuous release of LRH-At. These results are consistent with the idea that dopamine acts directly at the pituitary level as a GtH release-inhibitory factor in goldfish.

References (25)

  • Cooperative Team for Hormonal Application in Pisciculture

    A new highly effective ovulating agent for fish reproduction — practical application of LH-RH analogue for the induction of spawning of farm fishes

    Sci. Sinica

    (1977)
  • L.W. Crim et al.

    Manipulation of the seasonal reproductive cycle of the landlocked salmon (Salmo salar) by LHRH analogues administered at various stages of gonadal development

    Can. J. Fish. Aquatic Sci.

    (1983)
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