Chiral separation of barbiturates and hydantoins by reversed-phase high-performance liquid chromatography using a 25 or 50 mm short ODS cartridge column via β-cyclodextrin inclusion complexes

https://doi.org/10.1016/0378-4347(92)80389-8Get rights and content

Abstract

A high-performance liquid chromatographic method on a 25 or 50 mm short ODS cartridge column has been developed for the resolution of the enantiomers of some optically active barbiturates and hydantoins in human serum. β-Cyclodextrin was used in the mobile phase. This method also seems to be an easy and effective way to test whether β-cyclodextrin would be a useful chiral discriminator for a particular racemate.

References (10)

  • S. Eto et al.

    J. Chromatogr.

    (1991)
  • M. Seno et al.

    J. Chromatogr.

    (1990)
  • D.W. Armstrong et al.

    J. Chromatogr. Sci.

    (1984)
  • M.H.H. Chandler et al.

    J. Chromatogr.

    (1987)
  • J. McClanahan et al.

    J. Chromatogr.

    (1986)
There are more references available in the full text version of this article.

Cited by (0)

View full text