Synthesis, siderophore, and antimicrobial evaluation of a spermidine-based tricatecholate siderophore and carbacephalosporin conjugate
References (16)
- et al.
J. Am. Chem. Soc.
(1979)et al.J. Med. Chem.
(1981) - et al.
Bioconj. Chem.
(1991) - et al.
J. Med. Chem.
(1989) - et al.
Biol. Metals
(1991)et al.J. Med. Chem.
(1990)et al.J. Med. Chem.
(1991)Chem. Rev.
(1989) - et al.
Biochemistry
(1968)
There are more references available in the full text version of this article.
Cited by (7)
Antimicrobial effects of novel siderophores linked to β-Lactam antibiotics
2000, Bioorganic and Medicinal ChemistryCitation Excerpt :For the majority of the bromomethyl derivatives, attachment to the cephalosporin nucleus at the 3-methylene could be achieved by a convergent route from intermediate 89 (Scheme 7). We also synthesized 90, 91 and 92 as control analogues lacking the siderophore, and 93 as a positive control.12,13 Siderophores 24 and 25 that were active as determined by growth promotion alone were able to give rise to antibiotics (104 and 105 respectively) having antipseudomonal activity.
Siderophore conjugates
2013, Annals of the New York Academy of SciencesStudies and syntheses of siderophores, microbial iron chelators, and analogs as potential drug delivery agents
2000, Current Medicinal ChemistryNovel anti-pseudomonas cephalosporins
1997, Current Pharmaceutical DesignSpecies selectivity of new siderophore-drug conjugates that use specific iron uptake for entry into bacteria
1996, Antimicrobial Agents and ChemotherapyAn access to optically active carbacephems
1996, Heterocycles
Copyright © 1991 Published by Elsevier Ltd.