An -Adrenergic Agonist: Protonated Oxymetazoline Hydrochloride Monohydrate

The title compound, 2-[tert-butyl-(2,6-dimethyl-5-hydroxyphenyl)methyl]- 4,5-dihydro-1H,3H⁺-imidazolium chloride monohydrate, C₁₆H₂₅N₂O⁺·Cl^-·H₂O, is a sympathomimetic amine containing an imidazole ring. The ring is protonated with the positive charge dispersed over both of the N atoms, which are involved in hydrogen bonding, one with the Cl^- ion and the other with a water-O atom. The dihedral angle between the phenyl and imidazole rings is 86.3 (3)°.