Abstract
In 2,4-dichloro-5-ethylthiomethylpyrimidines3a, b and in (2,4-dichloro-5-pyrimidinylmethyl)ethyl sulfones5a, b, resp., by reaction with ammonia, diethyl-amine, isopropylamine, sodium methanolate and sodium ethylthiolate, resp., the halogen atoms have been substituted by amino, methoxy or ethylthio groups, resp., and thus the compounds4a–4r and5c–5f have been obtained.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literatur
Chemie der Pflanzenschutz- und Schädlingsbekämpfungsmittel (Wegler R., Hrsg.), Bd. 8, S. 406. Berlin-Heidelberg-New York: Springer. 1982.
Produits Chimiques Ugine Kuhlmann (Erf.Balde D. H.,Boutemy G. E. M.), Eur. Pat. Appl. 21 939 (10. 6. 1980) [Chem. Abstr.95, 7391 f (1981)].
Ciba-Geigy A.-G. (Erf.Hoegerle K.,Tobler H.), Eur. Pat. Appl. 24 260 (11. 8. 1980) [Chem. Abstr.95, 97836 z (1985)].
Eichberger G.,Hayden W.,Schwarz W.,Griengl H., Chemietage der GöCh, Linz, 25.–27. September 1985.
Cline R. E., Fink R. M., Fink K., J. Amer. Chem. Soc.81, 2581 (1959).
Kircher W., Liebigs Ann. Chem.385, 293 (1911).
Giner-Sorolla A., Medrek L., J. Med. Chem.9, 27 (1966).
Brossmer G., Röhm E., Liebigs Ann. Chem.692, 119 (1966).
Hasegawa M., Pharm. Bull. (Japan)1, 387 (1953).
Mattioda G., Obellianne P., Gauthier H., Loiseau G., Millischer R., Donadieu A., Mestre M., J. Med. Chem.18, 553 (1975).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Eichberger, G., Hayden, W., Schwarz, W. et al. 5-Ethylthiomethyl- und 5-Ethylsulfonylmethylpyrimidine. Monatsh Chem 117, 385–392 (1986). https://doi.org/10.1007/BF00816533
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00816533