Summary
The divergence pattern of mammalian ZFY-related genes from human (ZFY and ZFX) and mouse (Zfy-1 and Zfx) was reexamined on the basis of nucleotide substitutions at the synonymous codon-alternating positions. It is possible to explain the unusual divergence pattern of the mammalian Y-linked ZF genes by interchromosomal gene conversion by X-linked ZF genes. Furthermore, the rates of evolution of mammalian X- and Y-linked ZF genes were shown to agree well with those expected from our model.
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References
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Hayashida, H., Kuma, Ki. & Miyata, T. Interchromosomal gene conversion as a possible mechanism for explaining divergence patterns of ZFY-related genes. J Mol Evol 35, 181–183 (1992). https://doi.org/10.1007/BF00183228
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DOI: https://doi.org/10.1007/BF00183228