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Presence of a pineal nerve in sheep and rabbit fetuses

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Summary

The presence of a nerve located just caudal to the pineal gland in the mid-sagittal plane is demonstrated in sheep and rabbit fetuses. This nerve lies freely in the subarachnoid space and extends from the pineal gland to a region of the CNS located dorsal to the rostralmost part of the subcommissural organ (SCO). In rabbit fetuses the nerve is observed on days 23 and 24 of gestation; we suggest that it is an ontogenetic equivalent to the pineal nerve of anuran amphibians. The developmental fate of the mammalian fetal pineal nerve is discussed.

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References

  • Böttger, W. V., Böttger, E.-M.: Degenerationstudien am Nervus pinealis von Rana esculenta L. nach stirnorgannaher und -ferner Durchtrennung. Z. Zellforsch. 136, 365–391 (1973)

    Google Scholar 

  • David, G. F. X., Herbert, J.: Experimental evidence for a synaptic connection between habenula and pineal ganglion in the ferret. Brain Res. 64, 327–343 (1973)

    Google Scholar 

  • David, G. F. X., Herbert, J., Wright, G. D. S.: The ultrastructure of the pineal ganglion in the ferret. J. Anat. (Lond.) 115, 79–97 (1973)

    Google Scholar 

  • Diederen, J. H. B.: The subcommissural organ of Rana temporaria I. A cytological, cytochemical, cyto-enzymological and electron-microscopical study. Z. Zellforsch. 111, 379–403 (1970)

    Google Scholar 

  • Gardner, J. H.: Innervation of pineal gland in hooded rat. J. comp. Neurol. 99, 319–329 (1953)

    Google Scholar 

  • Hafeez, M. A., Zerihun, L.: Studies on central projections of the pineal nerve tract in rainbow trout, Salmo gairdneri Richardson, using cobalt chloride iontophoresis. Cell Tiss. Res. 154, 485–510 (1974)

    Google Scholar 

  • Kappers, J. Ariëns: The development, topographical relations and innervation of the epiphysis cerebri in the albino rat. Z. Zellforsch. 52, 163–215 (1960)

    Google Scholar 

  • Kappers, J. Ariëns: Survey of the innervation of the epiphysis cerebri and the accessory pineal organ of vertebrates. Progr. Brain Res. 10, 87–151 (1965)

    Google Scholar 

  • Kenny, G. C. T.: The “nervus conarii” of the monkey. An experimental study. J. Neuropath, exp. Neurol. 20, 563–570 (1961)

    Google Scholar 

  • Kolmer, W., Löwy, R.: Beiträge zur Physiologie der Zirbeldrüse. Pflügers Arch. ges. Physiol. 196, 1–14 (1922)

    Google Scholar 

  • Le Gros Clark, W. E.: The nervous and vascular relations of the pineal gland. J. Anat. (Lond.) 74, 471–492 (1940)

    Google Scholar 

  • Menaker, M., Oksche, A.: The avian pineal organ. In: Avian biology, Vol. 4 (eds.: Donald S. Farner and James R. King), p. 79–118. New York and London: Academic Press 1974

    Google Scholar 

  • Møllgård, K., Møller, M.: On the innervation of the human fetal pineal gland. Brain Res. 52, 428–432 (1973)

    Google Scholar 

  • Paul, E.: Innervation und zentralnervöse Verbindungen des Frontalorgans von Rana temporaria und Rana esculenta. Faserdegeneration nach operativer Unterbrechung des Nervus pinealis. Z. Zellforsch. 128, 504–511 (1971)

    Google Scholar 

  • Pines, L.: Über die Innervation der Epiphyse. Z. ges. Neurol. Psychiat. 111, 356–369 (1927)

    Google Scholar 

  • Rodríguez, E. M.: Ependymal specializations. III. Ultrastructural aspects of the basal secretion of the toad subcommissural organ. Z. Zellforsch. 111, 32–50 (1970)

    Google Scholar 

  • Romijn, H. J.: Structure and innervation of the pineal gland of the rabbit, Oryctolagus cuniculus (L.), with some functional considerations. Thesis (Amsterdam) 1972

  • Romijn, H. J.: Parasympathetic innervation of the rabbit pineal gland. Brain Res. 55, 431–436 (1973)

    Google Scholar 

  • Scharenberg, K., Liss, L.: The histologic structure of the human pineal body. Progr. Brain Res. 10, 193–217 (1965)

    Google Scholar 

  • Ueck, M., Vaupel-von Harnack, M., Morita, Y.: Weitere experimentelle und neuroanatomische Untersuchungen an den Nervenbahnen des Pinealkomplexes der Anuren. Z. Zellforsch. 116, 250–274 (1971)

    Google Scholar 

  • Wake, K., Ueck, M., Oksche, A.: Acetylcholinesterase-containing nerve cells in the pineal complex and subcommissural area of the frogs, Rana ridibunda and Rana esculenta. Cell Tiss. Res. 154, 423–442 (1974)

    Google Scholar 

  • Wurtman, R. J., Axelrod, J., Kelly, D. E.: The pineal. New York: Academic press 1968

    Google Scholar 

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Acknowledgement: The authors wish to thank Drs. N. Saunders, J. Reynolds and M. Reynolds, Department of Physiology, University College, London, for providing the sheep material.

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Møller, M., Møllgård, K. & Kimble, J.E. Presence of a pineal nerve in sheep and rabbit fetuses. Cell Tissue Res. 158, 451–459 (1975). https://doi.org/10.1007/BF00220212

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  • DOI: https://doi.org/10.1007/BF00220212

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