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No evidence for linkage between the loci for coagulation factor XIII-A and HLA

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Summary

The linkage analysis between the locus for coagulation factor XIII-A (F13A) and HLA region genes (HLA-A,-C,-B) was performed. In males, the maximum of lod scores between F13A and HLA was 0.33 at θ=0.30, and in females lod scores were negative at all values of θ. The results provided no evidence for close linkage between F13A and HLA genes.

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Authors and Affiliations

  1. Department of anthropology, Faculty of Science, The Universtiy of Tokyo, Hongo, Bunkyo-Ku, 113, Tokyo, Japan

    Toshinori Nishigaki, Katsushi Tokunaga, Chikara Ishii & Keiichi Omoto

  2. Tissue Typing Laboratory, Nagoya Daini Red Cross Hospital, Nagoya, Japan

    Tatsuo Akaza

  3. Department of Organ Transplantation, Institute of Medical Science, University of Tokyo, Tokyo, Japan

    Nobuo Akiyama

  4. Blood Transfusion Service, Tokyo University Hospital, Tokyo, Japan

    Takeo Juji

  5. Department of Research, Kumagaya Red Cross Blood Center, Kumagaya, Japan

    Sunao Murata

  6. Department of Internal Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan

    Setsuya Naito

  7. Department of Technology, Kyoto Red Cross Blood Center, Kyoto, Japan

    Hiroo Saji

  8. Central Clinical Laboratory, Kyushu University Hospital, Fukuoka, Japan

    Hiroyuki Satoh

  9. Aichi Red Cross Blood Center, Nagoya, Japan

    Tohru Shiraki

  10. Fukuoka Red Cross Blood Center, Fukuoka, Japan

    Kazuo Tokunaga

  11. Division of Genetics, National Institute of Radiological Sciences, Chiba, Japan

    Norikazu Yasuda

Authors
  1. Toshinori Nishigaki
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  2. Katsushi Tokunaga
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  3. Chikara Ishii
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  4. Keiichi Omoto
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  5. Tatsuo Akaza
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  6. Nobuo Akiyama
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  7. Takeo Juji
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  8. Sunao Murata
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  9. Setsuya Naito
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  10. Hiroo Saji
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  11. Hiroyuki Satoh
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  12. Tohru Shiraki
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  13. Kazuo Tokunaga
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  14. Norikazu Yasuda
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Nishigaki, T., Tokunaga, K., Ishii, C. et al. No evidence for linkage between the loci for coagulation factor XIII-A and HLA. Hum Genet 72, 266–267 (1986). https://doi.org/10.1007/BF00291893

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  • DOI: https://doi.org/10.1007/BF00291893

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