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Y-body in hair roots

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Summary

A method for identifying of the Y-Body in cells from hair root sheaths by fluorescent staining is described. In 52 normal males the Y-Body is found between 15 and 64%. 2 bodies were observed in 60 out of 5200 cells. In the female controls only rarely a fluorescent body was seen. The method is useful for screening tests in population genetics for identification of male sex-chromosome aberrations.

Zusammenfassung

Es wird über eine Methode zur Identifizierung von Y-Körperchen in Haarwurzelzellen mittels Fluorescenzfärbung berichtet. In den Zellen von 52 normalen Männern konnte das Y-Körperchen in einem Prozentsatz zwischen 15 und 64 nachgewiesen werden. 2 Y-Körperchen fanden sich unter 5200 Zellen nur 60mal. Bei normalen Frauen findet sich ein Fluorescenzkörperchen nur äußerst selten. Die Methode eignet sich für Screening-Untersuchungen zum Auffinden Y-chromosomaler Aberrationen.

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References

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Authors and Affiliations

  1. Institut für Gerich tliche Medizin der Universität Bonn, Bonn, Germany

    E. Schwinger, E. Rakebrand, H. -J. Müller, Erica M. Bühler & U. Tettenborn

  2. Abteilung Genetik, Universitäts-Kinderhospital, Basel, Switzerland

    E. Schwinger, E. Rakebrand, H. -J. Müller, Erica M. Bühler & U. Tettenborn

  3. Abteilung für Kinderpathologie, Pathologisches Institut der Universität Bonn, Bonn, Germany

    E. Schwinger, E. Rakebrand, H. -J. Müller, Erica M. Bühler & U. Tettenborn

Authors
  1. E. Schwinger
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  2. E. Rakebrand
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  3. H. -J. Müller
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  4. Erica M. Bühler
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  5. U. Tettenborn
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Additional information

Partly supported by Landesamt für Forschung des Landes Nordrhein-Westfalen.

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Schwinger, E., Rakebrand, E., Müller, H.J. et al. Y-body in hair roots. Hum Genet 12, 79–80 (1971). https://doi.org/10.1007/BF00291039

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  • DOI: https://doi.org/10.1007/BF00291039

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