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TheUbx syndrome ofDrosophila: the prothoracic transformation (ppx) is independent ofbx, bxd andpbx

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Summary

If, early in development, theUbx + gene is removed by mitotic recombination from cells of the meso-and metathoracic leg primordia, theseUbx cells develop as in the posterior prothoracic leg. We show that this transformation, termedpostprothorax, is a discrete genetic function that is independent of other homeotic transformations such asbx, pbx orbxd, which also result from the inactivation of theUbx gene.

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References

  • Bender W, Akam M, Karch F, Beachy PA, Peifer M, Spierer P, Lewis EB, Hogness DS (1983) Molecular genetics of the Bithorax complex inDrosophila melanogaster. Science221:23–29

    Google Scholar 

  • Hayes PH, Sato T, Denell RE (1984) Homoeosis inDrosophila: TheUltrabithorax larval syndrome. Proc Natl Acad Sci [USA] [in press]

  • Kerridge S, Morata G (1982) Developmental effects of some newly inducedUltrabithorax alleles ofDrosophila. J Embryol Exp Morphol68:211–234

    PubMed  Google Scholar 

  • Lindsley DL, Grell EM (1968) Genetic variations ofDrosophila melanogaster. Carnegie Inst Wash Publ No 627

  • Lewis EB (1963) Genes and developmental pathways. Am Zool3:33–56

    Google Scholar 

  • Lewis EB (1978) A gene complex controlling segmentation inDrosophila. Nature276:565–570

    PubMed  Google Scholar 

  • Lewis RA, Wakimoto BT, Denell RE, Kaufman TC (1980) Genetic analysis of the Antennapedia gene complex (ANT-C) ofDrosophila melanogaster. Polytene chromosome segments 84 A-84 B1-2. Genetics95:383–397

    Google Scholar 

  • Miñana FJ, García-Bellido A (1982) Preblastoderm mosaics of mutants of the Bithorax complex. Wilhelm Roux' Arch191:331–334

    Google Scholar 

  • Morata G, Botas J, Kerridge S, Struhl G (1983) Homeotic transformations of the abdominal segements ofDrosophila caused by breaking or deleting a central portion of the Bithorax complex. J Embryol Exp Morphol78:319–341

    PubMed  Google Scholar 

  • Morata G, Kerridge S (1980) An analysis of the expressivity of somebithorax transformations. In: Sidìqqi O, Babu P, Hall C, Hall H (eds) Development and Neurobiology of Drosophila. Plenum Press, London, pp 141–154

    Google Scholar 

  • Morata G, Kerridge S (1981) Sequential functions of the Bithorax complex ofDrosophila. Nature290:778–781

    PubMed  Google Scholar 

  • Morata G, Ripoll P (1975) Minutes: Mutants ofDrosophila autonomously affecting cell division rate. Dev Biol42:211–221

    PubMed  Google Scholar 

  • Struhl G (1981) A gene product required for correct initiation of segmental determination inDrosophila. Nature293:36–41

    PubMed  Google Scholar 

  • Struhl G (1982) Genes controlling segmental specification in theDrosophila thorax. Proc Natl Acad Sci79:7380–7384

    PubMed  Google Scholar 

Download references

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Sánchez-Herrero, E., Morata, G. TheUbx syndrome ofDrosophila: the prothoracic transformation (ppx) is independent ofbx, bxd andpbx . Wilhelm Roux' Archiv 193, 263–265 (1984). https://doi.org/10.1007/BF01260349

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  • DOI: https://doi.org/10.1007/BF01260349

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