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Immunohistochemical demonstration of a dermorphin-like peptide in the rat brain

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Summary

The new opioid heptapeptide dermorphin, first isolated from frog skin, has been localized immunohistochemically in nerve cell bodies and nerve fibers of the arcuate-periarcuate region, around the organum vasculosum of the lamina terminalis (OVLT) and in the subfornical organ of the rat brain. A role of dermorphin in modulating LHRH release is suggested.

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Authors and Affiliations

  1. Center of Diagnostic Histopathology, University of Pavia at Varese, I-21100, Varese, Italy

    R. Buffa & E. Magnoni

  2. Institute of Pathologic Anatomy, University of Pavia, Via Forlanini 16, I-27100, Pavia, Italy

    E. Solcia & G. Rindi

  3. Institute of Pharmacology, University of Rome, Rome, Italy

    L. Negri & P. Melchiorri

Authors
  1. R. Buffa
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  2. E. Solcia
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  3. E. Magnoni
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  4. G. Rindi
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  5. L. Negri
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  6. P. Melchiorri
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Buffa, R., Solcia, E., Magnoni, E. et al. Immunohistochemical demonstration of a dermorphin-like peptide in the rat brain. Histochemistry 76, 273–276 (1982). https://doi.org/10.1007/BF00501929

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  • DOI: https://doi.org/10.1007/BF00501929

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