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Native and reconstituted chromosome fiber fragments

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Abstract

The structure of hen erythrocyte chromatin fibers was studied with the electron microscope. Chromatin fiber fragments with a length of about 5,000 Å and an average diameter of 320 Å are composed of 13 globular subunits (superbeads) which contain different numbers of nucleosomes. Their number average corresponds to 17 nucleosomes. — The interaction of lysine-rich histones with nucleosome chains was investigated by reconstitution experiments and was found to be semi-cooperative.

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Meyer, G.F., Renz, M. Native and reconstituted chromosome fiber fragments. Chromosoma 75, 177–184 (1979). https://doi.org/10.1007/BF00292206

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  • DOI: https://doi.org/10.1007/BF00292206

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