Skip to main content
SpringerLink
Log in

Genetically controlled chromosome breakage and reunions in the meiosis

  • Published:
Chromosoma Aims and scope Submit manuscript

Abstract

Three mutants of Pisum sativum showing anomalies in the conjugation phase of meiosis, were investigated cytogenetically. Inspite of apparent normal chromosome pairing there is a strong reduction of chiasma number resulting into univalent formation. Simultaneously, chromosome aberrations appear as consequence of breakage and reunions in the prophase stage. The combined occurrence of these anomalies and their respective quantitative relationships to each other have been explained in the light of “breakage-reunion hypothesis” through the action of following factors: pairing behaviour, breakage frequency, number of breakages at one locus in the chromatid tetrads, behaviour of breakage ends and effects of environment. Due to the interaction of these factors all the anomalies found in our mutants are explainable.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Haga, T.: Meiosis in Paris. II. Spontaneous breakage and fusion of chromosomes. Cytologia (Tokyo) 18, 50–66 (1953).

    Google Scholar 

  • Jones, G. H.: The control of chiasma distribution in rye. Chromosoma (Berl.) 22, 69–90 (1967).

    Google Scholar 

  • Klein, H. D.: Desynapsis und Chromosomenbrüche in einer Mutante von Pisum sativum. Mutation Res. 8, 277–284 (1969).

    Google Scholar 

  • Lewis, K. R., John, B.: The meiotic consequences of spontaneous chromosome breakage. Chromosoma (Berl.) 18, 287–304 (1966).

    Google Scholar 

  • Matsuura, H.: Chromosome studies on Trillium kamtschaticum Pall. and its allies. XIX. Chromosome breakage and reunion at chiasmata. Cytologia (Tokyo) 16, 48–57 (1950).

    Google Scholar 

  • McClintock, B.: Cytological observations of deficiences involving known genes, translocations and inversions in Zea mays. Univ. Coll. Agr. Exp. Stat. Res. Bull. 163, 1–30 (1931).

    Google Scholar 

  • Rees, H., Thompson, J. B.: Localisation of chromosome breakage in rye. Heredity 9, 399–407 (1955).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Genetics, University of Bonn, Germany

    H. D. Klein & S. R. Baquar

  2. P.C.S.I.R. Laboratories, Karachi

    H. D. Klein & S. R. Baquar

Authors
  1. H. D. Klein
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S. R. Baquar
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

This study was supported by the Euratom I.T.A.L. and the Ministry of Science and Education, BRD. The second author is presently on a post doctoral fellowship of the Humboldt-Foundation.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Klein, H.D., Baquar, S.R. Genetically controlled chromosome breakage and reunions in the meiosis. Chromosoma 37, 223–231 (1972). https://doi.org/10.1007/BF00284941

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00284941

Keywords

Search

Navigation