Summary
A mutation (modG) was selected on the basis of the suppression of a defect resulting from a mutation of modD gene. The modG mutation shows the same developmental consequences as modD mutations: the absence of protoperithecia and aerial hyphae, the non-renewal of growth from stationary cells and the non-germination of ascospores. Investigations of heterokaryotic mycelia showed that the action of modD and modG mutations on the formation of protoperithecia and aerial hyphae is autonomous. Furthermore, taking advantage of the thermosensitivity of a modD mutation, it was shown that the mutations have no incidence on cell differentiation prior to the achievement of stationary physiology. These findings lead to suggest the existence, in Podospora anserina, of a stage of cell totipotency, which we call the switch stage, that derives from the stationary state through the action of modD and mode genes. Accordingly, the switch stage would be the intermediate in the process of growth renewal from stationary cells and the basic stage for the selection of the developmental alternatives (aerial hyphae, protoperithecia ...) of Podospora mycelia.
Similar content being viewed by others
References
Bégueret J, Labarère J (1971) Ann Gen Vol: la recombinaison bactérienne, hémotypologie et cytogénétique, p 97–102
Belcour L, Bernet J (1969) CR Acad Sci (Paris) D 269:712–714
Bernet J (1965) Ann Sci Natl Bot 6:611–768
Bernet J (1971) CR Acad Sci (Paris) D 273:1120–1122
Bernet J, Belcour L (1967) CR Acad Sci (Paris) D 265:1536–1539
Boucherie H (1979) Thesis Université Bordeaux II
Boucherie H, Bernet J (1974) Mol Gen Genet 135:163–174
Boucherie H, Bernet J (1980) Genetics 96:399–411
Delettre YM, Bernet J (1976) Mol Gen Genet 144:191–197
Durrens P, Laigret F, Labarère J, Bernet J (1979) J Bacteriol 140: 835–842
Esser K (1974) Podospora anserina. In: King RC (ed) Handbook of Genetics, vol 1. Plenum Press, New York, London p 531–551
Johnson TE (1978) Genetics 88:27–47
Labarère J, Bernet J (1977) Genetics 87:249–257
Labarère J, Bernet J (1978) J Gen Microbiol 109:187–189
Labarère J, Bernet J (1979a) J Gen Microbiol 113/19–28
Labarère J, Bernet J (1979b) Genetics 93/525–537
Mylyk OM, Threlkeld SFH (1974) Genet Res 24:91–102
Srb AM, Nasrallah JB, Basl M (1973) Brookhaven Symp Biol 25:40–50
Tan ST, Ho CC (1970) Mol Gen Genet 107:158–161
Wheeler HE, McGahen JW (1952) Am J Bot 39:110–119
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Durren, P., Berne, J. Podospora anserina mutations inhibiting several developmental alternatives and growth renewal. Curr Genet 5, 181–186 (1982). https://doi.org/10.1007/BF00391803
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00391803