Skip to main content
Log in

Suppression of temperature sensitive mutations in oncogene-related CDC genes in Saccharomyces cerevisiae by catabolite repression resistance and cytoplasmic petite mutations

  • Published:
Current Genetics Aims and scope Submit manuscript

Summary

The “start” cell division control genes CDC36 and CDC28 have been reported to contain a certain sequence homology to tissue oncogenes (ets and some protein kinase encoding oncogenes respectively). Here we report that temperature sensitive mutations in these genes are suppressed in cytoplasmic “petite” mutants and catabolite repression resistant mutants.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Aisenberg AC (1961) The glycolysis and respiration of tumors. Academic Press, New York London, pp 1–31, 121–159

    Google Scholar 

  • Barnett JA (1976) Adv Carbohydr Chem Biochem 32:125–235

    Google Scholar 

  • Criss WE (1971) Cancer Res 31:1523–1542

    Google Scholar 

  • Deuel TF, Huang JS (1984) J Clin Invest 74:669–676

    Google Scholar 

  • Diamond I, Legg A, Schneider JA, Rozengurt E (1978) J Biol Chem 253:866–871

    Google Scholar 

  • Egilsson V, Evans IH, Wilkie D (1979) Mol Gen Genet 174:39–46

    Google Scholar 

  • Entian K-D, Fröhlich K-U (1984) J Bacteriol 158:29–35

    Google Scholar 

  • Fowell RR (1969) Sporulation and hybridization of yeast. In: Rose AH, Harrison JS (eds) The yeasts, vol 1. Academic Press, New York London, pp 303–383

    Google Scholar 

  • Furst A, Michels CA (1977) Mol Gen Genet 155:309–315

    Google Scholar 

  • Gudnason V, Ingvarsson S, Jonasdottir A, Andresdottir V, Egilsson V (1984) Int J Cancer 34:63–66

    Google Scholar 

  • Haussmann P, Zimmermann FK (1976) Mol Gen Genet 148:205–211

    Google Scholar 

  • Kataoka T, Powers S, McGill C, Fasano O, Strathern J, Broach J, Wigler M (1984) Cell 37:437–445

    Google Scholar 

  • Kolarov J, Kužela S, Krempasky V, Ujháky V (1973) Biochem Biophys Res Commun 55:1173–1179

    Google Scholar 

  • Lörincz AT, Reed SI (1984) Nature (London) 307:183–185

    Google Scholar 

  • Neal DE, Marsh C, Bennett MK, Abel PD, Hall RR, Sainsbury JRC, Harris AL (1985) Lancet 1:366–371

    Google Scholar 

  • Pedersen PL (1978) Prog Exp Tumor Res 22:194–274

    Google Scholar 

  • Peterson TA, Yochem J, Byers B, Nunn MF, Duesberg PH, Doolittle RF, Reed SI (1984) Nature (London) 309:556–558

    Google Scholar 

  • Rapp GR (1973) Cancer 31:357–360

    Google Scholar 

  • Reed SI (1980) Genetics 95:561–577

    Google Scholar 

  • Shuster JR (1982) J Bacteriol 151:1059–1061

    Google Scholar 

  • Warburg O (1926) Über den Stoffwechsel der Tumoren. Springer, Berlin

    Google Scholar 

  • Warburg O (1956) Science 123:309–311

    Google Scholar 

  • Wilkie D, Evans IH, Egilsson V, Diala ES, Collier D (1983) Int Rev Cytol [Suppl] 15:157–189

    Google Scholar 

  • Witt I, Kronau R, Holzer H (1966) Biochim Biophys Acta 118:522–537

    Google Scholar 

  • Wyke J (1975) Biochim Biophys Acta 417:91–121

    Google Scholar 

  • Zimmermann FK, Kaufmann I, Raisenberger H, Haussmann P (1977) Mol Gen Genet 151:95–103

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Egilsson, V., Gudnason, V., Jonasdottir, A. et al. Suppression of temperature sensitive mutations in oncogene-related CDC genes in Saccharomyces cerevisiae by catabolite repression resistance and cytoplasmic petite mutations. Curr Genet 10, 35–37 (1985). https://doi.org/10.1007/BF00418491

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00418491

Key words

Navigation