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The production of Non-H-2 histocompatibility alloantibodies in the mouse

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Abstract

Alloantibodies specific for non-H-2 histocompatibility antigens of the mouse have been produced. Immunization (BALB/cJ×DBA/2J)F1 anti-B10.D2/n was conducted, followed by hemagglutination, immunofluorescence, and mixed hemabsorption tests on absorbed and unabsorbed sera. The results indicate that antibodies specific for H-3a and H-8a antigens are present. In addition, H-8a antigenic determinants were detected on erythrocyte membrane surfaces, as well as on cells of other body tissues.

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Zink, G.L., Heyner, S. The production of Non-H-2 histocompatibility alloantibodies in the mouse. Immunogenetics 4, 257–266 (1977). https://doi.org/10.1007/BF01575665

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