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NH2-terminal sequence of the α and β chains of human DC-1 antigen isolated from the JY cell line. Homology with murine I-A molecules

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Abstract

The DC-1 antigen has been isolated from the JY cell line (DR4, w6). The amino terminal sequences of its α and β chains are both reported and are homologous to the murine I-A antigens. The JY and previously reported LB DC-1 α chain sequences appear to be variants of the.DC α chains reported by other authors. The JY DC-1 β chain sequence appears to be identical with that deduced from a β chain cDNA clone and thus identifies this clone. The JY and LB DC-1 β-chains are clearly different since the latter has a blocked amino terminus.

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  1. Department of Biochemistry and Molecular Biology, Harvard University, 7 Divinity Avenue, 02138, Cambridge, Massachusetts

    M. Rosa Bono & Jack L. Strominger

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  1. M. Rosa Bono
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  2. Jack L. Strominger
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Bono, M.R., Strominger, J.L. NH2-terminal sequence of the α and β chains of human DC-1 antigen isolated from the JY cell line. Homology with murine I-A molecules. Immunogenetics 18, 453–459 (1983). https://doi.org/10.1007/BF00364387

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  • DOI: https://doi.org/10.1007/BF00364387

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