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Application of HPLC column-switching in pesticide residue analysis

  • Methods For Pesticide Residue Analysis
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Summary

An overview is given of the applicability of HPLC with column-switching in pesticide residue analysis. The main advantage of HPLC with column-switching is the enhancement of both sensitivity and selectivity combined with a high potential for automation. The selection of optimal conditions such as column dimensions, mobile phase compositions and multi step gradient elution is discussed.

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Author notes

  1. C. E. Goewie

    Present address: DHV Raadgevend Ingenieursbureau BV, P.O. Box 85, NL-3800 AB, Amersfoort, The Netherlands

Authors and Affiliations

  1. National Institute of Public Health and Environmental Protection, P.O. Box 1, NL-3720 BA, Bilthoven, The Netherlands

    E. A. Hogendoorn, C. E. Goewie & P. van Zoonen

Authors
  1. E. A. Hogendoorn
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  2. C. E. Goewie
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  3. P. van Zoonen
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Hogendoorn, E.A., Goewie, C.E. & van Zoonen, P. Application of HPLC column-switching in pesticide residue analysis. Fresenius J Anal Chem 339, 348–356 (1991). https://doi.org/10.1007/BF00322347

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  • DOI: https://doi.org/10.1007/BF00322347

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