Skip to main content
SpringerLink
Log in

A human X-linked antigen defined by a monoclonal antibody

  • Published:
Somatic Cell Genetics

Abstract

We have constructed hybrids between human thymocytes and the mouse thymoma BW5147. These hybrids, and others, have been used to show that the expression of a thymocyte antigen is controlled by an X-linked gene.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature cited

  1. Puck, T.T., Wuthier, P., Jones, C., and Kao, F. (1971).Proc. Natl. Acad. Sci. U.S.A. 68:3102–3106.

    PubMed  Google Scholar 

  2. Goodfellow, P.N., Jones, E.A., van Heyningen, V., Solomon, E., Bobrow, M., Miggiano, V., and Bodmer, W.F. (1975).Nature 254:267–269.

    PubMed  Google Scholar 

  3. van Someran, H., Westerveld, A., Hagemeijer, A., Mees, J.R., Meera Khan, P., and Zaalberg, O.B. (1974).Proc Natl. Acad. Sci. U.S.A. 71:962–965.

    PubMed  Google Scholar 

  4. Buck, D., and Bodmer, W.F. (1975). Human gene mapping 2.Birth Defects: Orig. Artic. Ser. 11 3:87–89.

    Google Scholar 

  5. Buck, D., and Bodmer, W.F. (1976). Human gene mapping 3.Birth Defects: Orig. Artic. Ser. 127:376–377.

    Google Scholar 

  6. Aden, D.P., and Knowles B.B. (1976).Immunogenetics 3:209–211.

    Google Scholar 

  7. Fellous, M., Bengtsson, B., Finnegan, D., and Bodmer, W.F. (1974).Ann Hum. Genet. 37:421–430.

    PubMed  Google Scholar 

  8. Mann, J.D., Cahan, A., Gelb, A.G., Fisher, N., Hamper, J., Tippett, P., Sanger, R., and Race, R.R. (1962).Lancet 1:8–10.

    PubMed  Google Scholar 

  9. Hsu, H.S., Migeon, B.R., and Bias, W.B. (1976). Human gene mapping 3.Birth Defects: Orig. Artic. Ser. 127:382–385.

    Google Scholar 

  10. Dorman, B.P., Shimizu, N., and Ruddle, F.H. (1978).Proc. Natl. Acad. Sci. U.S.A. 75:2363–2367.

    PubMed  Google Scholar 

  11. Schwab, R., and Siniscalo, M. (1978). Human gene mapping 4.Birth Defects: Orig. Artic. Ser. 144:538–540.

    Google Scholar 

  12. Evans, H.J., Hamerton, J.L., Klinger, H.P., and McKusick, V.A. (eds.) (1979). Human gene mapping 5.Birth Defects: Orig. Artic. Ser. 1511:1–236.

    Google Scholar 

  13. Kohler, G., and Milstein, C. (1975).Nature 256:495–497.

    PubMed  Google Scholar 

  14. Barnstable, C.J., Bodmer, W.F., Brown, G., Galfre, G., Milstein, C., Williams, A.F., and Ziegler, A. (1979).Cell 14:9–20.

    Google Scholar 

  15. McMichael, A.J., Pilch, J.R., Galfre, G., Mason, D.Y., Fabre, J.W., and Milstein, C. (1979).Eur. J. Immunol. 9:205–211.

    PubMed  Google Scholar 

  16. Ziegler, A., and Milstein, C. (1979)Nature 279:243–294.

    PubMed  Google Scholar 

  17. Levy, R., Dilley, J., Fox, R.I. and Warnke, R. (1979).Proc. Natl. Acad. Sci. U.S.A. 76:6552–6556.

    PubMed  Google Scholar 

  18. Davidson, R.L. (1974).Annu. Rev. Genet. 8:195–218.

    PubMed  Google Scholar 

  19. Hyman, R., and Stallings, V. (1974).J. Natl. Cancer Inst. 52:429–436.

    PubMed  Google Scholar 

  20. Nabholz, M., Miggiano, V., and Bodmer, W.F. (1969).Nature 223:358–363.

    PubMed  Google Scholar 

  21. Oi, V.T., Jones, P.P., Goding, J.W., Herzenberg, L.A., and Herzenberg, L.A. (1979)Curr. Top. Microbiol. Immunol. 81:115–129.

    Google Scholar 

  22. Minowada, J., Ohnuma, T., and Moore, G.E. (1972).J. Natl. Cancer. Inst. 49:891–895.

    PubMed  Google Scholar 

  23. Royston, I., Smith, R.W., Buell, D.W., Huang, E.S., and Pagano, J.S. (1974).Nature 251:745–746.

    PubMed  Google Scholar 

  24. Solomon, E., Bobrow, M., Goodfellow, P.N., Bodmer, W.F., Swallow, D.M., Povey, S., and Noel, B. (1976).Somat. Cell Genet. 2:125–140.

    PubMed  Google Scholar 

  25. Bobrow, M., and Cross, J. (1974).Nature 257:77–79.

    Google Scholar 

  26. Harris, H., and Hopkinson, D.A. (1976).Handbook of Enzyme Electrophoresis in Human Genetics, Suppl. 1977 and 1978. (North Holland Publishing Co., Amsterdam).

    Google Scholar 

  27. Goodfellow, P.N., Levinson, J.R., Williams, V.E., and McDevitt, H.O. (1979).Proc. Natl. Acad. Sci. U.S.A. 76:377–380.

    PubMed  Google Scholar 

  28. Charron, D.J., and McDevitt, H.O. (1979).Proc. Natl. Acad. Sci. U.S.A. 76:6567–6571.

    PubMed  Google Scholar 

  29. Tan, Y.H., Tischfield, J., and Ruddle, F.H. (1973).J. Exp. Med. 137:317–330.

    PubMed  Google Scholar 

  30. Fisher, R.A., Povey, S., Bobrow, M., Solomon, E., Boyd, Y., and Carritt, B. (1977).Ann. Hum. Genet. 41:150–155.

    Google Scholar 

  31. van Heyningen, V., Bobrow, M., Bodmer, W.F., Gardiner, S.E., Povey, S., and Hopkinson, D.A. (1975).Ann. Hum. Genet. 38:295–303.

    PubMed  Google Scholar 

  32. Jones, E.A., Goodfellow, P.N., Kennett, R.H., and Bodmer, W.F. (1976).Somat. Cell Genet. 2:483–496.

    Google Scholar 

  33. Goodfellow, P.N. (1976). D. Phil. Thesis, Oxford University, Oxford, U.K.

    Google Scholar 

  34. Suomalainen, H.A., Goldsby, R.A., Osborne, B.A., and Schroder, J. (1980).Scand. J. Immunol. 11:163–168.

    PubMed  Google Scholar 

  35. Buck, D., Goss, S.J., and Bodmer, W.F. (1976). Human gene mapping 3.Birth Defects: Orig. Artic. Ser. 127:99–100.

    Google Scholar 

  36. Shapiro, L.J., Weiss R., Buxman, M.M., Vidgoff, J., Dimond, R.L., Roller, J.A., and Wells, R.S. (1978).Lancet 2:756–757.

    PubMed  Google Scholar 

  37. Adam, A., Ziprkowsks, L., Fenstein, A., Sanger, R., Tippett, P., Gavin, J., and Race R.R. (1969).Ann. Hum. Genet. 32:323–332.

    PubMed  Google Scholar 

  38. Mohandas, T., Shapiro, L.J., Sparkes, R.S., and Sparkes, M.C. (1979). Human gene mapping 5.Birth Defects: Orig. Artic. Ser. 1511:187.

    Google Scholar 

  39. Shapiro, L.J., Mohandas, T., Weiss, R., and Romer, G. (1979).Science 204:1224–1226.

    PubMed  Google Scholar 

  40. Balazs, I., Filippi, G., Rinaldi, A., Grzeschik, K.H., and Siniscalco, M. (1979). Human gene mapping 5.Birth Defects: Orig. Artic. Ser. 1511:133.

    Google Scholar 

  41. Huber, B., Gershon, R.K., and Cantor, H. (1976).J. Exp. Med. 145:10–20.

    Google Scholar 

  42. Zeicher, M., Mozes, E., Reisner, Y., and Lonai, P. (1979).Immunogenetics 9:119–124.

    Google Scholar 

  43. Seligman, M., Fudenberg, H.H., and Good, R.A. (1968).Am. J. Med. 45:817–825.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Central Research Division, Imperial Cancer Research Fund, Lincoln's Inn Fields, WC2, London, England

    P. Goodfellow & G. Banting

  2. Division of Oncology, Department of Medicine, Stanford Medical Center, Stanford, California

    R. Levy

  3. MRC Human Biochemical Genetics Unit, Galton Laboratory, University College, London, England

    S. Povey

  4. Nuffield Department of Medicine, Radcliffe Infirmary, University of Oxford, England

    A. McMichael

Authors
  1. P. Goodfellow
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. Banting
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. R. Levy
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. S. Povey
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. A. McMichael
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Goodfellow, P., Banting, G., Levy, R. et al. A human X-linked antigen defined by a monoclonal antibody. Somat Cell Mol Genet 6, 777–787 (1980). https://doi.org/10.1007/BF01538976

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01538976

Keywords

Search

Navigation