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The biosynthesis of glycolipids during the differentiation of the slime mold dictyostelium discoideum

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Summary

In the slime mold Dictyostelium discoideum polyisoprenylphosphomannosides are substrates for membrane bound mannosyltransferases; the isolated and purified isoprenyl derivatives transfer mannose to protein in vitro in presence of membrane fractions. The biosynthesis of the mannolipids as well as the biosynthesis of a glucose containing cerebroside, which becomes synthesized in an early stage of the cell development proceeds under control of the cell differentiation. The isolation procedure and the properties of the glycolipids are described, and their functions for the cellular development are discussed.

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Rössler, H., Peuckert, W., Risse, H.J. et al. The biosynthesis of glycolipids during the differentiation of the slime mold dictyostelium discoideum. Mol Cell Biochem 20, 3–15 (1978). https://doi.org/10.1007/BF00229450

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  • DOI: https://doi.org/10.1007/BF00229450

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