Abstract
Streptavidin and avidin were adsorbed onto graphite surfaces and images of their structures were obtained using a scanning tunnelling microscope. Individual protein molecules and their subunits were observed, and their sizes were found to agree closely with measurements from a subunit model based upon the crystal structure of streptavidin. The process of adsorption of streptavidin-FITC and avidin succinylfluorescein isothiocyanate onto the graphite surface was also investigated using fluorescence microscopy.
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Cooper, J.M., Shen, J., Young, F.M. et al. The imaging of streptavidin and avidin using scanning tunnelling microscopy. J Mater Sci: Mater Electron 5, 106–110 (1994). https://doi.org/10.1007/BF00187121
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DOI: https://doi.org/10.1007/BF00187121