This is a preview of subscription content, log in via an institution to check access.
References
Betke, K., Marti, H. R., and Schlicht, I. (1959). Estimation of small percentages of foetal haemoglobin. Nature 1841877.
Feingold, E. A., Collins, F. S., Weatherall, J. E., Stoeckert, C. J., Jr., Weissman, S. M., and Forget, B. G. (1985). Molecular analysis of deletion and nondeletion hereditary persistence of fetal hemoglobin and identification of a new mutation causing β-thalassemia. N.Y. Acad. Sci. 443159.
Gilman, J. G., and Huisman, T. H. J. (1984). Two independent genetic factors in the β-globin gene cluster are associated with high Gγ levels in the Hb F of SS patients. Blood 64452.
Gilman, J. G., and Huisman, T. H. J. (1985). DNA sequence variation associated with elevated fetal Gγ globin production. Blood 66783.
Harano, T., Reese, A. L., Ryan, R., Abraham, B. L., and Huisman, T. H. J. (1985). Five haplotypes in Black β-thalassaemia heterozygotes: Three are associated with high and two with low Gγ values in fetal haemoglobin. Br. J. Haematol. 59333.
Kutlar, A., Gardiner, M. B., Headlee, M. G., Reese, A. L., Cleek, M. P., Nagle, S., Sukumaran, P. K., and Huisman, T. H. J. (1984). Heterogeneity in the molecular basis of three types of hereditary persistence of fetal hemoglobin and the relative synthesis of the Gγ and Aγ types of γ chain. Biochem. Genet. 2221.
Orkin, S. H., Kazazian, H. H., Jr., Antonarakis, S. E., Goff, S. C., Boehm, C. D., Sexton, J. P., Waber, P. G., and Giardina, P. J. V. (1982). Linkage of β-thalassaemia mutations and β-globin gene polymorphisms with DNA polymorphisms in human β globin gene cluster. Nature 296627.
Poncz, M., Solowiejczyk, D., Harpel, B., Mory, Y., Schwartz, E., and Surrey, S. (1982). Construction of human gene libraries from small amounts of peripheral blood: Analysis of β-like globin genes. Hemoglobin 627.
Shelton, J. B., Shelton, J. R., and Schroeder, W. A. (1984). High performance liquid chromatographic separation of globin chains on a large-pore C4 column. J. Liq. Chromatogr. 71969.
Shimizu, K., Harano, T., Harano, K., Miwa, S., Amenomori, Y., Ohba, Y., Kutlar, F., and Huisman, T. H. J. (1986). Abnormal arrangements in the α and γ globin gene clusters in a relatively large group of Japanese newborns. Am. J. Hum. Genet. (in press).
Author information
Authors and Affiliations
Additional information
This research was supported by USDAS Research Grants HLB 05168 and HLB 15158. This is contribution 0932 of the Department of Cell and Molecular Biology, Medical College of Georgia, Augusta.
Rights and permissions
About this article
Cite this article
Bakioglu, I., Kutlar, A. & Huisman, T.H.J. Differences between the levels of Gγ chain in the fetal hemoglobin in two types of hereditary persistence of fetal hemoglobin are linked with a variation in the DNA sequence. Biochem Genet 24, 149–151 (1986). https://doi.org/10.1007/BF00502985
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF00502985