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Linkage of diabetes insipidus and agouti genes in the rat

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Abstract

Linkage of the hooded (h), agouti (A), and diabetes insipidus (di) genes was found in (ACI×DI)F1×DI backcross rats. The genetic map distance A-di for females and for males was 19±5 and 28±5 cM, respectively. However, this difference was not significant. The combined data showed the map distance to be 25±4 cM. The three-point cross showed the following corrected distances and order of genes: h-42±4-A-25±4-di. However, the linkage of h and A, although significant (x2=9.03, P<0.001), is only tentative and must be confirmed by additional studies.

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  1. Department of Pathology, School of Medicine, University of Pittsburgh, 15261, Pittsburgh, Pennsylvania

    Viktor Stolc

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Stolc, V. Linkage of diabetes insipidus and agouti genes in the rat. Biochem Genet 22, 893–899 (1984). https://doi.org/10.1007/BF00499480

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  • DOI: https://doi.org/10.1007/BF00499480

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