Abstract
Only one molecular form of trehalase (E.C. 3.2.1.28) was detectable in adult Drosophila melanogaster by polyacrylamide gel electrophoresis and isoelectric focusing. An examination of duplication- and deletion-bearing aneuploids exhibiting do sage sensitivity indicated that the enzyme is encoded by a gene, Treh +, located between 55B and 55E of the second chromosome. The tissue-specific soluble and particulate forms of trehalase appear to be manifestations of a single protein encoded by a single gene.
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This work was supported by NRC Grants A5860 to J. H. Williamson and A4691 to R. E. Huber.
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Oliver, M.J., Huber, R.E. & Williamson, J.H. Genetic and biochemical aspects of trehalase from Drosophila melanogaster . Biochem Genet 16, 927–940 (1978). https://doi.org/10.1007/BF00483744
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DOI: https://doi.org/10.1007/BF00483744