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Neurochemical characteristics of the effects of delta sleep-inducing peptide in wistar rats with hyperactivity of the dopaminergic system

  • Biophysics and Biochemistry
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Quantitative cytochemical assay showed that single injection of delta sleep-inducing peptide increased monoamine oxidase activity (substrates: serotonin and tryptamine) in the caudate and accumbens nuclei and glutamate dehydrogenase activity in the hippocampus of stress-resistant Wistar rats chronically treated with L-DOPA. Enzyme activities in the sensorimotor cortex did not change. Delta sleep-inducing peptide had no effects on acetylcholine esterase and aminopeptides activities in the brain of Wistar rats.

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References

  1. L. M. Gershtein,Tsitologiya,7, No. 6, 769–773 (1965).

    CAS  Google Scholar 

  2. V. M. Svetukhina,Arkh. Anat.,42, No. 2, 31–45 (1962).

    CAS  PubMed  Google Scholar 

  3. A. V. Sergutina,Morfologiya,113, No. 1, 51–53 (1998).

    CAS  Google Scholar 

  4. A. V. Sergutina, and V. I. Rakhmanova,,113, No. 6, 9–11 (1999).

    Google Scholar 

  5. N. S. Popova, E. L. Dovedova, and O. S. Adrianov,Fiziol. Zh. SSSR,23, No. 6, 730–737 (1987).

    Google Scholar 

  6. N. S. Popova, and L. M. Kachalova,Zh. Vyssh. Nervn. Deyat.,41, No. 1, 9–30 (1991).

    CAS  Google Scholar 

  7. G. G. Glenner, H. I. Burtner, and G. W. Brown,J. Histochem. Cytochem.,5, No. 6, 591–600 (1957).

    Article  CAS  PubMed  Google Scholar 

  8. M. J. Karnovsky, and J. Roots,,12, No. 3, 219–221 (1964).

    Article  CAS  PubMed  Google Scholar 

  9. L. J. Rubinstein, J. Klatso, and J. Miguel,J. Neuropathol. Exp. Neurol.,21, 116–136 (1962).

    Article  CAS  PubMed  Google Scholar 

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Translated fromByulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 130,No. 11, pp. 537–539, November, 2000

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Sergutina, A.V., Gershtein, L.M. Neurochemical characteristics of the effects of delta sleep-inducing peptide in wistar rats with hyperactivity of the dopaminergic system. Bull Exp Biol Med 130, 1074–1076 (2000). https://doi.org/10.1023/A:1002891517101

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  • DOI: https://doi.org/10.1023/A:1002891517101

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