Abstract
Carbon dioxide is shown to inhibit the generation of superoxide anion radical in bioptates both directly exposed to CO2 and after preliminary exposure of the whole organism to CO2. A similar effect is noted for gas mixtures similar in composition to arterial and venous blood. The results substantiate the important evolutionary role of CO2 for the maintenance of life on Earth with the appearance of potentially toxic oxygen.
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References
I. I. Borzenkova, M. I. Bud'ko, E. K. Byutner,et al., in:Man-Induced Changes of the Climate [in Russian], Leningrad (1987), p. 405.
A. Kh. Kogan, S. V. Grachev, and S. V. Eliseeva,Dokl. Ross. Akad. Nauk,340, No. 1, 132–134 (1995).
A. Kh. Kogan, B. M. Manuilov, S. V. Grachev,et al., Byull. Eksp. Biol. Med.,118, No. 10, 395–398 (1994).
A. Kh. Kogan, B. M. Manuilov, and S. V. Grachev,Fiziol. Cheloveka,21, No. 4, 128–136 (1995).
A. Kh. Kogan, I. V. Khapugina, M. I. Rasulov,et al., Byull. Izobret., No. 21 (1996).
R. F. Schmidt and G. Thews, in:Human Physiology, Berlin (1989), p. 507.
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Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, No. 4, pp. 407–410, April, 1996
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Kogan, A.K., Grachev, S.V. & Eliseeva, S.V. CO2 inhibition of the generation of reactive oxygen species in cells of internal organs and its biological importance. Bull Exp Biol Med 121, 371–373 (1996). https://doi.org/10.1007/BF02446730
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DOI: https://doi.org/10.1007/BF02446730