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DNA homology between Candida albicans strains: Evidence to justify the synonymous status of C. stellatoidea

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Abstract

Genetic relatedness between strains of C. albicans and C. stellatoidea was studied by measuring G + C content and overall sequence homology. G + C contents determined by high-performance liquid chromatography were 32.6 to 34.2% for 26 strains of C. albicans and 33.0 to 33.9% for eight strains of C. stellatoidea. DNA-DNA hybridization with two C. albicans and two C. stellatoidea probes revealed that all 34 test strains formed a single cluster in which the extents of hybridization with the heterologous probes ranged between 77.9 and 105.6% of those with the homologous probes. These results give support to the unification of C. albicans and C. stellatoidea into a single species.

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Kamiyama, A., Niimi, M., Tokunaga, M. et al. DNA homology between Candida albicans strains: Evidence to justify the synonymous status of C. stellatoidea . Mycopathologia 107, 3–7 (1989). https://doi.org/10.1007/BF00437584

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